Takayasu Hajime 高安肇

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TAKAYASU Hajime 高安肇

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Researcher Number	10359614
Affiliation (Current)	2025: 北里大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022: 北里大学, 医学部, 講師 2017 – 2021: 筑波大学, 医学医療系, 准教授 2013 – 2015: 筑波大学, 医学医療系, 講師 2003 – 2005: 獨協医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Pediatric surgery / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Pediatric surgery
Keywords	Principal Investigator ナイトロフェン / 肺高血圧 / ラットモデル / 先天性横隔膜ヘルニア / 胎児薬物治療 / 胎児治療 / エリスロポエチン / 薬物療法 / ナイトロフェンラットモデル / Rho阻害剤 … More / 肺低形成 / 新生児先天性横隔膜ヘルニア / CD47 / TSP1 / Wntシグナル伝達系 / Rho Kinase阻害剤 / 横隔膜ヘルニア / Rhoキナーゼ / RhoA … More Except Principal Investigator Oxidative DNA damage / Low birth weight infants / Hepatoblastoma / β-catenin / Superoxide dismutase / 8-OHdG / βカテニン / 酸素 / AFP / 遺伝子発現 / 胎児ラット / 酸化ストレス / DNA酸化障害 / 低出生体重児 / 肝芽腫 Less

Candidate Drugs Exploration for Congenital Diaphragmatic Hernia Fetal TreatmentPrincipal Investigator
- Principal Investigator
  
  高安肇
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kitasato University
  University of Tsukuba
Investigation of candidate drugs for pulmonary hypertension associated with congenital diaphragmatic herniaPrincipal Investigator
- Principal Investigator
  
  Takayasu Hajime
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  University of Tsukuba
The effectiveness of erythropoietin for the pulmonary hypertension with the congenital diaphragmatic hernia patientsPrincipal Investigator
- Principal Investigator
  
  Takayasu Hajime
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  University of Tsukuba
Mechanisms of Hepatoblastoma Carcinogenesis in Low Birth Weight Infants
- Principal Investigator
  
  IKEDA Hitoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Dokkyo Medical University

All 2023 2022 2021 2019 2016 2015 2014 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Upregulated TSP1 and CD47 expression in the lung in nitrofen‐induced congenital diaphragmatic hernia2023
- Author(s)
  Takayasu Hajime
- Journal Title
  
  Pediatrics International
  
  Volume: 65 Issue: 1
- DOI
  10.1111/ped.15447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08592
[Journal Article] Growth Assessment and the Risk of Growth Retardation in Congenital Diaphragmatic Hernia: A Long-Term Follow-Up Study from the Japanese Congenital Diaphragmatic Hernia Study Grou2016
- Author(s)
  Terui K, Nagata K, Hayakawa M, Okuyama H, Goishi K, Yokoi A, Tazuke Y, Takayasu H, Yoshida H, Usui N.
- Journal Title
  
  Eur J Pediatric Surg.
  
  Volume: 26 Issue: 01 Pages: 60-6
- DOI
  10.1055/s-0035-1566094
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462769, KAKENHI-PROJECT-26462709, KAKENHI-PROJECT-26293252, KAKENHI-PROJECT-16K15534
[Journal Article] Japanese Congenital Diaphragmatic Hernia Study Group. Musculoskeletal abnormalities in congenital diaphragmatic hernia survivors: Patterns and risk factors: report of a Japanese multicenter follow-up survey.2016
- Author(s)
  Takayasu H, Masumoto K, Goishi K, Hayakawa M, Tazuke Y, Yokoi A, Terui K, Okuyama H, Usui N, Nagata K, Taguchi T
- Journal Title
  
  Pediatr Int.
  
  Volume: 未定 Issue: 9 Pages: 877-880
- DOI
  10.1111/ped.12922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462769, KAKENHI-PROJECT-26293252, KAKENHI-PROJECT-16K15534
[Journal Article] Analysis of risk factors of long-term complications in congenital diaphragmatic hernia: A single institution's experience.2015
- Author(s)
  Takayasu H, Masumoto K, Jimbo T, Sakamoto N, Sasaki T, Uesugi T, Gotoh C, Urita Y, Shinkai T.
- Journal Title
  
  Asian J Surg.
  
  Volume: in Press Issue: 1 Pages: 1-5
- DOI
  10.1016/j.asjsur.2015.02.005
- NAID
  120007134917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462769
[Journal Article] Increased pulmonary RhoA expression in the nitrofen-induced congenital diaphragmatic hernia rat model.2015
- Author(s)
  Takayasu H, Masumoto K, Hagiwara K, Sasaki T, Ono K, Jimbo T, Uesugi T, Gotoh C, Urita Y, Shinkai T, Tanaka H.
- Journal Title
  
  J Pediatr Surg.
  
  Volume: 50 Issue: 9 Pages: 1467-71
- DOI
  10.1016/j.jpedsurg.2015.02.063
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462769
[Journal Article] Hypoxia-hyperoxia stress affects fetal rat hepatocyte differentiation2005
- Author(s)
  Takayasu H
- Journal Title
  
  J Jpn Soc Pediatr Surg 41(3)
  
  Pages: 347-347
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591892
[Journal Article] Hypoxia-hyperoxia stress affects fetal rat hepatocyte differentiation2005
- Author(s)
  Takayasu H
- Journal Title
  
  日本小児外科学会雑誌 41・3
  
  Pages: 347-347
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591892
[Journal Article] Oxidative DNA damage and β-catenin status under hypoxia-hyperoxia stresses in newborn rat hepatocytes2004
- Author(s)
  Takayasu H
- Journal Title
  
  Pediatr Blood Cancer 43(4)
  
  Pages: 382-382
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591892
[Journal Article] Oxidative DNA damage and β-catenin status under hypoxia-hyperoxia stresses in newborn rat hepatocytes2004
- Author(s)
  Takayasu H
- Journal Title
  
  Pediatr Blood Cancer 43・4
  
  Pages: 382-382
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591892
[Journal Article] 肝芽腫とβ-カテニン異常2003
- Author(s)
  高安肇
- Journal Title
  
  小児外科 35・5
  
  Pages: 522-527
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591892
[Journal Article] β-catenin abnormality found in hepatoblastomas2003
- Author(s)
  Takayasu H
- Journal Title
  
  Jpn J Pediatr Surg 35(5)
  
  Pages: 522-527
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591892
[Presentation] Upregulated TSP1 and CD47 Expression in the Lung in Nitrofen-induced Congenital Diaphragmatic Hernia2022
- Author(s)
  Hajime Takayasu
- Organizer
  第35回International Symposium on Pediatric Surgical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08592
[Presentation] 先天性横隔膜ヘルニアRatモデルにおけるCD47とTSP1の高発現2021
- Author(s)
  高安　肇、増本幸二
- Organizer
  第58回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08592
[Presentation] 先天性横隔膜ヘルニアRatモデルにおけるCD47とTSP1の高発現2021
- Author(s)
  高安　肇、増本幸二
- Organizer
  第112回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11505
[Presentation] Long-term Follow-up in Surgical Newborns: A single institution’s experience2019
- Author(s)
  Hajime Takayasu, Kouji Masumoto, Kazuki Shirane, Yasunari Tanaka, Tsubasa Aiyoshi, Takato Sasaki, Kentaro Ono, Fumiko Chiba, Chikashi Gotoh, Yasuhisa Urita, Toko Shinkai
- Organizer
  52nd PAPS Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11505
[Presentation] 当院における新生児外科手術症例の長期フォローの状況について2019
- Author(s)
  高安肇, 増本幸二, 田中保成, 相吉翼, 佐々木理人, 小野健太郎, 千葉史子, 五藤周, 瓜田泰久, 新開統子
- Organizer
  第55回日本周産期・新生児医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11505
[Presentation] Long-term Follow-up in Surgical Newborns: A single institution’s experience2019
- Author(s)
  Hajime Takayasu, Kouji Masumoto, Kazuki Shirane, Yasunari Tanaka, Tsubasa Aiyoshi, Takato Sasaki, Kentaro Ono, Fumiko Chiba, Chikashi Gotoh, Yasuhisa Urita, Toko Shinkai
- Organizer
  Pacific Association of Pediatric Surgeons 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11505
[Presentation] 当院における新生児外科手術症例の長期フォローの状況について2019
- Author(s)
  高安肇, 増本幸二, 田中保成, 相吉翼, 佐々木理人, 小野健太郎, 千葉史子, 五藤周, 瓜田泰久, 新開統子
- Organizer
  第56回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11505
[Presentation] 先天性横隔膜ヘルニアラットモデル腎臓におけるエリスロポエチン産生の抑制2016
- Author(s)
  高安　肇　増本幸二　萩原幸輝　南　洋輔　後藤悠大　千葉史子　坂元直哉　五藤　周　瓜田泰久　新開統子　田中秀明
- Organizer
  第53回日本小児外科学会
- Place of Presentation
  博多、ヒルトン福岡シーホーク
- Year and Date
  2016-05-24
- Data Source
  KAKENHI-PROJECT-25462769
[Presentation] Musculoskeletal Abnormalities in Congenital Diaphragmatic Hernia Survivors: Patterns and Risk Factors - Report From A Multicenter Follow-up Survey -2015
- Author(s)
  Hajime Takayasu, Kouji Masumoto, Keiji Goishi, Masahiro Hayakawa, Yuko Tazuke, Akiko Yokoi, Keita Terui, Hiroomi Okuyama, Noriaki Usui, Kouji Nagata, and Tomoaki Taguchi
- Organizer
  第52回日本小児外科学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-25462769
[Presentation] Growth Assessments and The Risk of Growth Retardation In Congenital Diaphragmatic Hernia: The Multicenter Follow-Up Study2015
- Author(s)
  Keita Terui , Tomoaki Taguchi, Masahiro Hayakawa, Hiroomi Okuyama, Keiji Goishi, Akiko Yokoi, Yuko Tazuke, Hajime Takayasu, Hideo Yoshida, Noriaki Usui and The Japanese Congenital Diaphragmatic Hernia Study Group
- Organizer
  第16回ヨーロッパ小児外科学会
- Place of Presentation
  リャブナ、スロベニア
- Year and Date
  2015-06-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462769
[Presentation] Suppressed Erythropyetin Expression in the Liver in Nitrofen-induced Congenital Diaphragmatic Hernia.2015
- Author(s)
  Hajime Takayasu, Kouji Masumoto, Koki Hagiwara, Takato Sasaki, Fumiko Chiba, Naoya Sakamoto, Chikashi Gotoh, Yasuhisa Urita, Makoto Nakao, Toko Shinkai, Hideaki Tanaka
- Organizer
  アジア太平洋小児外科学会2015
- Place of Presentation
  チェジュ島、韓国
- Year and Date
  2015-05-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462769
[Presentation] NitrofenラットモデルにおけるWnt4遺伝子発現の検討2014
- Author(s)
  高安　肇、増本幸二、新開統子、田中秀明、瓜田泰久、五藤　周、上杉　達、神保教広、小野健太郎、佐々木理人
- Organizer
  第51回日本小児外科学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25462769
[Presentation] INCREASED PUMONARY RHOA EXPRESSION IN THE NITROFEN-INDUCED CONGENITAL DIAPHRAGMATIC HERNIA.2014
- Author(s)
  Hajime Takayasu ,Kouji Masumoto Kouki Hagiwara Takahiro Jimbo Takato Sasaki Kentaro Ono Toru Uesugi Chikashi Gotoh Yasuhisa Urita Toko Shinkai Hideaki Tanaka
- Organizer
  ヨーロッパ小児外科学会
- Place of Presentation
  ダブリン、アイルランド
- Data Source
  KAKENHI-PROJECT-25462769
[Presentation] Suppressed Erythropyetin Expression in the Liver in Nitrofen-induced Congenital Diaphragmatic Hernia.
- Author(s)
  Hajime Takayasu, Kouji Masumoto, Koki Hagiwara, Shunsuke Fujii, Tsubasa Aiyoshi, Takato Sasaki, Fumiko Chiba, Naoya Sakamoto, Chikashi Gotoh, Yasuhisa Urita, Makoto Nakao, Toko Shinkai, Hideaki Tanaka
- Organizer
  太平洋小児外科学会
- Place of Presentation
  チェジュ島、韓国
- Year and Date
  2015-05-17 – 2015-05-21
- Data Source
  KAKENHI-PROJECT-25462769
[Presentation] Increased pulmonary RhoA expression in the nitrofen-induced congenital diaphragmatic hernia
- Author(s)
  Hajime Takayasu, Kouji Masumoto, Kouki Hagiwara, Takahiro Jimbo, Takato Sasaki, Kentaro Ono, Toru Uesugi, Chikashi Gotoh, Yasuhisa Urita, Toko Shinkai Hideaki Tanaka
- Organizer
  ヨーロッパ小児外科学会2014
- Place of Presentation
  アイルランド、ダブリン
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25462769

1. MASUMOTO Kouji (20343329)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. GOTOH Chikashi (80598889)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. UESUGI Toru (30380421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. IKEDA Hitoshi (10326928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISHIMARU Yuki (30233430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 瓜田泰久 (90361352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Takayasu Hajime 高安 肇

TAKAYASU Hajime 高安 肇

Research Projects

Research Products

Co-Researchers

Candidate Drugs Exploration for Congenital Diaphragmatic Hernia Fetal TreatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of candidate drugs for pulmonary hypertension associated with congenital diaphragmatic herniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effectiveness of erythropoietin for the pulmonary hypertension with the congenital diaphragmatic hernia patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of Hepatoblastoma Carcinogenesis in Low Birth Weight Infants

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Upregulated TSP1 and CD47 expression in the lung in nitrofen‐induced congenital diaphragmatic hernia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Growth Assessment and the Risk of Growth Retardation in Congenital Diaphragmatic Hernia: A Long-Term Follow-Up Study from the Japanese Congenital Diaphragmatic Hernia Study Grou2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Japanese Congenital Diaphragmatic Hernia Study Group. Musculoskeletal abnormalities in congenital diaphragmatic hernia survivors: Patterns and risk factors: report of a Japanese multicenter follow-up survey.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of risk factors of long-term complications in congenital diaphragmatic hernia: A single institution's experience.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Increased pulmonary RhoA expression in the nitrofen-induced congenital diaphragmatic hernia rat model.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypoxia-hyperoxia stress affects fetal rat hepatocyte differentiation2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hypoxia-hyperoxia stress affects fetal rat hepatocyte differentiation2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Oxidative DNA damage and β-catenin status under hypoxia-hyperoxia stresses in newborn rat hepatocytes2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Oxidative DNA damage and β-catenin status under hypoxia-hyperoxia stresses in newborn rat hepatocytes2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] 肝芽腫とβ-カテニン異常2003

Author(s)

Journal Title

Description

Data Source

Takayasu Hajime 高安肇

TAKAYASU Hajime 高安肇