SHIMIZU Nobutaka 清水信貴

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Shimizu Nobutaka 清水信貴

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Researcher Number	10368326
Other IDs
Affiliation (Current)	2026: 高知大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 高知大学, 教育研究部医療学系臨床医学部門, 准教授 2018 – 2020: 近畿大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related Except Principal Investigator Basic Section 56030:Urology-related / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 中枢神経 / 経鼻投与 / 過活動膀胱 / 後根神経根 / TRPV1 / 排尿筋過活動 / 脊髄損傷 / Laser Microdissection / β3 agonist / 脊髄後根神経節 … More / 膀胱求心路 / laser microdissection / β３アゴニスト / ウイルスベクター / TRP channel / 下部尿路機能障害 / 脊髄損傷マウス … More Except Principal Investigator VEGF / 低活動膀胱 / 排尿機能 / 脳・神経 / 薬理学 / プロスタグランジンE2 / ヒスタミン / 一酸化窒素 / ニコチン受容体 / 膀胱機能 / 頻尿 / 脳 / ストレス Less

経鼻投与で中枢神経系に迫る新規過活動膀胱治療薬の開発Principal Investigator
- Principal Investigator
  
  清水信貴
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kochi University
血管内皮増殖因子を用いた低活動膀胱治療法の開発
- Principal Investigator
  
  齊藤源顕
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kochi University
ストレス誘発性頻尿の脳内機序を標的とした頻尿治療法開発に向けた基盤構築
- Principal Investigator
  
  清水孝洋
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kochi University
Gene therapy with herpes simplex virus vectors improves lower urinary tract dysfunction in mice with spinal cord injuryPrincipal Investigator
- Principal Investigator
  
  Shimizu Nobutaka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kindai University

All 2025 2024 2020 2019 2018

All Journal Article Presentation

[Journal Article] Brain nitric oxide plays an inhibitory role in suppression of the rat micturition reflex induced by activation of brain α7 nicotinic acetylcholine receptors2024
- Author(s)
  Shimizu N, Shimizu T, Fukuhara H, Inoue K, Saito M
- Journal Title
  
  Continence
  
  Volume: 12S Pages: 101463-101463
- DOI
  10.1016/j.cont.2024.101463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06887
[Journal Article] Role of p38 MAP kinase signaling pathways in storage and voiding dysfunction in mice with spinal cord injury2020
- Author(s)
  Shimizu N, Wada N, Shimizu T, Suzuki T, Kurobe M, Kanai AJ, de Groat WC, Hashimoto M, Hirayama A, Uemura H, Yoshimura N
- Journal Title
  
  Neurourology and urodynamics
  
  Volume: 39 Pages: 108-115
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Journal Article] Effects of a new β3-adrenoceptor agonist, vibegron, on neurogenic bladder dysfunction and remodeling in mice with spinal cord injury2020
- Author(s)
  Daisuke Gotoh, Nobutaka Shimizu, Naoki Wada, Katsumi Kadekawa, Tetsuichi Saito , Shinsuke Mizoguchi , Yosuke Morizawa , Shunta Hori , Makito Miyake , Kazumasa Torimoto , William C de Groat , Kiyohide Fujimoto , Naoki Yoshimura
- Journal Title
  
  Neurourology and urodynamics
  
  Volume: 39 Pages: 2120-2127
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Journal Article] Efficacy of vibegron, a novel β3-adrenoreceptor agonist on storage and voiding dysfunction in mice with spinal cord injury.2020
- Author(s)
  Shimizu N, Nishimoto M, Hashimoto M, Saito T, Gotoh D, Hirayama A, Yoshimura N, Uemura H
- Journal Title
  
  Neurourology and urodynamics
  
  Volume: 39
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16751
[Journal Article] Effects of nerve growth factor neutralization on TRP channel expression in laser-captured bladder afferent neurons in mice with spinal cord injury2018
- Author(s)
  Shimizu N1, Wada N2, Shimizu T2, Suzuki T2, Takaoka EI2, Kanai AJ3, de Groat WC4, Hirayama A5, Hashimoto M6, Uemura H6, Yoshimura N7.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 683 Pages: 100103-100103
- DOI
  10.1016/j.neulet.2018.06.049
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Presentation] 脳内α7型ニコチン受容体刺激による排尿抑制に脳内一酸化炭素が関与する2025
- Author(s)
  手嶋勇斗、清水孝洋、齊藤源顕
- Organizer
  APPW2025（第１３０回日本解剖学会/第１０２回日本生理学会/第９８回日本薬理学会合同大会）
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] ラット脳室内へ投与されたヒスタミンは排尿を促進する2025
- Author(s)
  武内結生、清水孝洋、齊藤源顕
- Organizer
  APPW2025（第１３０回日本解剖学会/第１０２回日本生理学会/第９８回日本薬理学会合同大会）
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] 脳内一酸化窒素は脳内α7型ニコチン受容体を介した排尿抑制を負に制御する2025
- Author(s)
  清水孝洋、清水信貴、井上啓史、齊藤源顕
- Organizer
  APPW2025（第１３０回日本解剖学会/第１０２回日本生理学会/第９８回日本薬理学会合同大会）
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] 脳内α7型ニコチン受容体刺激による排尿抑制を脳内一酸化窒素は抑制性に制御する2024
- Author(s)
  清水孝洋、清水信貴、福原秀雄、井上啓史、齊藤源顕
- Organizer
  第７７回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] コラボ演題：泌尿器薬理学研究の盛り上げを目指す若手研究者たちからのメッセージ2024
- Author(s)
  清水孝洋、堀田祐志
- Organizer
  第８回黒潮カンファレンス
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] 脳内一酸化窒素は脳内α7型ニコチン受容体刺激による排尿抑制を負に制御する2024
- Author(s)
  清水信貴、清水孝洋、福原秀雄、井上啓史、齊藤源顕
- Organizer
  第３１回日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] ラット脳室内投与ヒスタミンは排尿促進に関与する2024
- Author(s)
  武内結生、清水孝洋、齊藤源顕
- Organizer
  第８回日本臨床薬理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] Brain nitric oxide plays an inhibitory role in suppression of the rat micturition reflex induced by activation of brain α7 nicotinic acetylcholine receptors2024
- Author(s)
  Shimizu N, Shimizu T, Fukuhara H, Inoue K, Saito M
- Organizer
  International Continence Society 54th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] 脳内α7型ニコチン受容体刺激による排尿抑制に対し脳内一酸化窒素は抑制性に関与する2024
- Author(s)
  清水孝洋、清水信貴、福原秀雄、井上啓史、齊藤源顕
- Organizer
  第４５回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06887
[Presentation] 脊髄損傷マウスモデルの膀胱機能障害に対するビベグロンの効果2020
- Author(s)
  清水信貴(近畿大学医学部泌尿器科), 西本光寿, 後藤大輔, 橋本士, 平山暁秀, 吉村直樹, 植村天受
- Organizer
  日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-18K16751
[Presentation] Efficacy of vibegron, a novel β3-adrenoreceptor agonist on storage and voiding dysfunction in mice with spinal cord injury2020
- Author(s)
  Shimizu N, Nishimoto M, Hashimoto M, Saito T, Gotoh D, Hirayama A, Yoshimura N, Uemura H
- Organizer
  50th International Continence Society (ICS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Presentation] Gene therapy with herpes simplex virus vectors encoding poreless TRPV1 or protein phosphatase 1α reduces detrusor overactivity in mice with spinal cord injury2020
- Author(s)
  清水信貴, 齋藤徹一, 後藤大輔, 馬嶋剛, 平山暁秀, 吉村直樹, 植村天受
- Organizer
  第108回　日本泌尿器科学会総会　international session
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Presentation] Therapeutic effects of PDE9 inhibitor on lower urinary tract dysfunction (LUTD) in mice with spinal cord injury (SCI)2019
- Author(s)
  Nobutaka Shimizu
- Organizer
  EAU
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Presentation] Therapeutic effects of p38 MAP kinase inhibitor on bladder dysfunction in mice with spinal cord injury (SCI)2019
- Author(s)
  Nobutaka Shimizu
- Organizer
  EAU
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Presentation] Gene therapy with replication-deficient herpes simplex virus vectors encoding poreless TRPV1 or protein phosphatase 1α (PP1α) reduces detrusor overactivity in mice with spinal cord injury2019
- Author(s)
  Nobutaka Shimizu
- Organizer
  International continence society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751
[Presentation] Therapeutic effects of PDE9 inhibitor on lower urinary tract dysfunction (LUTD) following spinal cord injury (SCI)2019
- Author(s)
  Nobutaka Shimizu
- Organizer
  SIU
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16751

1. 清水孝洋 (00363276)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. 齊藤源顕 (60273893)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 東洋一郎 (80380062)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 東郷未緒 (91008515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 齋藤源顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results

SHIMIZU Nobutaka 清水 信貴

Shimizu Nobutaka 清水 信貴

Research Projects

Research Products

Co-Researchers

経鼻投与で中枢神経系に迫る新規過活動膀胱治療薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

血管内皮増殖因子を用いた低活動膀胱治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ストレス誘発性頻尿の脳内機序を標的とした頻尿治療法開発に向けた基盤構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Gene therapy with herpes simplex virus vectors improves lower urinary tract dysfunction in mice with spinal cord injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Brain nitric oxide plays an inhibitory role in suppression of the rat micturition reflex induced by activation of brain α7 nicotinic acetylcholine receptors2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of p38 MAP kinase signaling pathways in storage and voiding dysfunction in mice with spinal cord injury2020

Author(s)

Journal Title

Data Source

[Journal Article] Effects of a new β3-adrenoceptor agonist, vibegron, on neurogenic bladder dysfunction and remodeling in mice with spinal cord injury2020

Author(s)

Journal Title

Data Source

[Journal Article] Efficacy of vibegron, a novel β3-adrenoreceptor agonist on storage and voiding dysfunction in mice with spinal cord injury.2020

Author(s)

Journal Title

Data Source

[Journal Article] Effects of nerve growth factor neutralization on TRP channel expression in laser-captured bladder afferent neurons in mice with spinal cord injury2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 脳内α7型ニコチン受容体刺激による排尿抑制に脳内一酸化炭素が関与する2025

Author(s)

Organizer

Data Source

[Presentation] ラット脳室内へ投与されたヒスタミンは排尿を促進する2025

Author(s)

Organizer

Data Source

[Presentation] 脳内一酸化窒素は脳内α7型ニコチン受容体を介した排尿抑制を負に制御する2025

Author(s)

Organizer

Data Source

[Presentation] 脳内α7型ニコチン受容体刺激による排尿抑制を脳内一酸化窒素は抑制性に制御する2024

Author(s)

Organizer

Data Source

[Presentation] コラボ演題：泌尿器薬理学研究の盛り上げを目指す若手研究者たちからのメッセージ2024

Author(s)

Organizer

Data Source

[Presentation] 脳内一酸化窒素は脳内α7型ニコチン受容体刺激による排尿抑制を負に制御する2024

Author(s)

Organizer

Data Source

[Presentation] ラット脳室内投与ヒスタミンは排尿促進に関与する2024

Author(s)

Organizer

Data Source

[Presentation] Brain nitric oxide plays an inhibitory role in suppression of the rat micturition reflex induced by activation of brain α7 nicotinic acetylcholine receptors2024

SHIMIZU Nobutaka 清水信貴

Shimizu Nobutaka 清水信貴