NAWACHI KUMIKO 縄稚久美子

… Alternative Names

NAWACHI Kumiko 縄稚久美子

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Researcher Number	10379787
Affiliation (Current)	2025: 岡山大学, 医療開発領域, 助教
Affiliation (based on the past Project Information) *help	2018 – 2023: 岡山大学, 大学病院, 助教 2017: 岡山大学, 医歯(薬)学総合研究科, 助教 2011 – 2016: 岡山大学, 大学病院, 助教 2012: 岡山大学, 岡山大学病院, 助教 2010: Okayama University, 医歯(薬)学総合研究科, 助教 … More 2007 – 2009: Okayama University, Graduate School of Medicine and Dentistry, Assistant Professor 2005 – 2006: 岡山大学, 大学院・医歯薬学総合研究科, 助手 2005: 岡山大学, 大学院医歯薬学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 57050:Prosthodontics-related / Dental engineering/Regenerative dentistry / Prosthodontics/ Dental materials science and / 補綴理工系歯学 / Prosthetic dentistry Except Principal Investigator 補綴理工系歯学
Keywords	Principal Investigator BMP-2 / 大腸菌 / 骨再生 / rhBMP-2 / 骨髄 / 大動物 / キャリア / 歯周病 / ゼラチンハイドロゲル / インプラント … More / 口腔インプラント / 角化歯肉 / トランスクリプトーム / トランスクリプトーム解析 / 歯肉角化 / MRONJ / 再生療法 / 人工骨 / Escherichia coli / large animal / carrier / periodontal disease / implant / bone regeneration / gelatin hydrogels / 骨吸収 / オッセオインテグレーション / 骨形成 / 血球系細胞 / 再生医学 / 歯槽骨再生 / BMP … More Except Principal Investigator QoL / Response Sift / multivariate analysis / Risk factor / Risk marker / Peri-implant sulcular fluids / Matrix metalloproteinases / Peri-implantitis / 力学的因子 / 骨破壊 / QOL / 可溶型レセプター / 単純除去率 / 残存率 / ELISA / 腫瘍壊死因子 / レスポンスシフト / 多変量解析 / リスク因子 / リスクマーカー / 歯肉溝滲出液 / コラゲナーゼ / インプラント周囲炎 / 自己骨髄由来間葉系幹細胞 / I型コラーゲン / ゼラチンハイドロゲル / FGF / BMP / CTGF / タンパク質導入法 / 歯槽骨再生 Less

時空間的トランスクリプトーム解析を応用した歯肉角化制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  縄稚久美子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Okayama University
Bone marrow microenvironment of MRONJ and application of Escherichia coli derived BMP-2Principal Investigator
- Principal Investigator
  
  Nawachi Kumiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Okayama University
Bone regenerative therapy using Escherichia coli-derived rhBMP-2 adsorbed in beta-TCP.Principal Investigator
- Principal Investigator
  
  NAWACHI Kumiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Okayama University
The mechanism identification of environmental selective bone induction/suppression of BMP-2Principal Investigator
- Principal Investigator
  
  Nawachi Kumiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Okayama University
Investigation of the mechanisms involving BMP-2-induced inhibition of bone formation or niche formation at the bone marrow microenvironment.Principal Investigator
- Principal Investigator
  
  NAWACHI Kumiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Okayama University
第二世代BMP-2を応用した口腔インプラントの骨結合促進と歯槽骨再生の実用化Principal Investigator
- Principal Investigator
  
  縄稚久美子
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Prosthetic dentistry
- Research Institution
  Okayama University
Bone regeneration with degradable hydrogels and genetically modified, recombinant human BMP-2 with two additional repeats of the heparin-binding domain.Principal Investigator
- Principal Investigator
  
  NAWACHI Kumiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University
Development of chair-side assay system for ongoing bone loss with peri-implant sulcus fluids
- Principal Investigator
  
  ARAKAWA Hikaru
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University
自己骨髄由来間葉系幹細胞にタンパク質導入法を応用した歯槽骨再生技術の開発
- Principal Investigator
  
  KANYAMA Manabu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University

All 2023 2021 2020 2019 2018 2009 2008 2007

All Journal Article Presentation Book

[Book] 補綴臨床別冊　保険適用新技術完全マスター！　第4章　口腔内装置　挿管時の歯の保護2018
- Author(s)
  縄稚久美子，前田あずさ，窪木拓男
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-16K11624
[Journal Article] Suppression of Bone Necrosis around Tooth Extraction Socket in a MRONJ-like Mouse Model by E-rhBMP-2 Containing Artificial Bone Graft Administration2021
- Author(s)
  Tanaka Yukie、Aung Kyaw Thu、Ono Mitsuaki、Mikai Akihiro、Dang Anh Tuan、Hara Emilio Satoshi、Tosa Ikue、Ishibashi Kei、Ono-Kimura Aya、Nawachi Kumiko、Kuboki Takuo、Oohashi Toshitaka
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 23 Pages: 12823-12823
- DOI
  10.3390/ijms222312823
- NAID
  120007183234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10246, KAKENHI-PROJECT-20K23110, KAKENHI-PROJECT-19H03842, KAKENHI-PROJECT-20K21678, KAKENHI-PROJECT-20K21679
[Journal Article] BMP-2/β-TCP Local Delivery for Bone Regeneration in MRONJ-Like Mouse Model2020
- Author(s)
  Mikai Akihiro、Ono Mitsuaki、Tosa Ikue、Nguyen Ha Thi Thu、Hara Emilio Satoshi、Nosho Shuji、Kimura-Ono Aya、Nawachi Kumiko、Takarada Takeshi、Kuboki Takuo、Oohashi Toshitaka
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 19 Pages: 7028-7028
- DOI
  10.3390/ijms21197028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10246, KAKENHI-PROJECT-20K21679, KAKENHI-PROJECT-20K23108, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-18H02991, KAKENHI-PROJECT-19H03842, KAKENHI-PROJECT-19K24146
[Journal Article] Loss of oral self-care ability results in higher risk of pneumonia in older inpatients: A prospective cohort study in a Japanese rural hospital.2019
- Author(s)
  Fujiwara A, Minakuchi H, Uehara J, Miki H, Inoue-Minakuchi M, Kimura-Ono A, Nawachi K, Maekawa K, Kuboki T.
- Journal Title
  
  Gerodontology
  
  Volume: in press Issue: 3 Pages: 236-243
- DOI
  10.1111/ger.12402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11590, KAKENHI-PROJECT-16K11624, KAKENHI-PROJECT-19K10225
[Journal Article] The effect of growth factors for bone augmentation to enable dental implantplacement : A systematic review.2009
- Author(s)
  Shimono K, Oshima M, Arakawa H, Nawachi K, Kuboki T.
- Journal Title
  
  Japanese Dental Science Review (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592268
[Presentation] Benefit of shape-maintaining and softened meals provided after implant surgery2023
- Author(s)
  K. Nawachi , Y. Kurosaki , A. Kimura Ono , T. Mino , T. Kuboki
- Organizer
  2024 IADR/AADOCR/CADR General Session
- Data Source
  KAKENHI-PROJECT-22K10100
[Presentation] Bone-inducing effects of rhBMP-2 and rhFGF-2 in bone marrow microenvironment2020
- Author(s)
  Shuji Nosho, Mitsuaki Ono, Akihiro Mikai, Kumiko Nawachi, Aya Kimura-Ono, Emilio S Hara, Takuo Kuboki, Toshitaka Oohashi
- Organizer
  International Association for Dental Research (IADR) 98th General Session and Exhibition and 49th Annual Meeting of the American Association for Dental Research (AADR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10246
[Presentation] BMP-2 local administration for MRONJ-mice induced partial bone regeneration.2020
- Author(s)
  Mikai A, Ono M, Nosho S, Tosa I, Hara ES, Kimura-Ono A, Nawachi K, Kuboki T, Oohashi T
- Organizer
  2020 IADR/AADR/CADR General Session & Exhibition.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10246
[Presentation] マウス薬剤関連性顎骨壊死モデルにおける BMP-2の骨形成能の検討2020
- Author(s)
  三海晃弘, 大野充昭, 納所秋二, 土佐郁恵, 縄稚久美子, 大野彩, 窪木拓男, 大橋俊孝
- Organizer
  岡山大学次世代研究拠点シンポジウム 2020
- Data Source
  KAKENHI-PROJECT-19K10246
[Presentation] BMP-2 local administration for MRONJ-mice induced partial bone regeneration2020
- Author(s)
  Akihiro Mikai, Mitsuaki Ono, Shuji Nosho, Ikue Tosa, Emilio S Hara, Aya Kimura-Ono, Kumiko Nawachi, Takuo Kuboki, Toshitaka Oohashi
- Organizer
  International Association for Dental Research (IADR) 98th General Session and Exhibition and 49th Annual Meeting of the American Association for Dental Research (AADR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10246
[Presentation] ベトナム北部医療系大学における国際臨床研究デザインワークショップの試み.2018
- Author(s)
  縄稚久美子，ハラエミリオサトシ，前田あずさ，窪木拓男
- Organizer
  第37回日本歯科医学教育学会総会および学術大会.
- Data Source
  KAKENHI-PROJECT-16K11624
[Presentation] 大腸菌由来・遺伝子組換BMP-2と塩基性ゼラチンを用いた骨補填材の効果.2008
- Author(s)
  下野賢吾, 縄稚久美子, ほか7名
- Organizer
  第21回日本歯科医学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-20592268
[Presentation] 大腸菌由来・遺伝子改変BMP-2と塩基性ゼラチンを用いた骨補填剤の効果2007
- Author(s)
  下野賢吾, 大島正充, 縄稚久美子, 完山学, Sebald W, 田畑泰彦, 洲鎌和茂, 窪木拓男
- Organizer
  日本補綴歯科学会中国四国支部サマースクール
- Place of Presentation
  徳島
- Year and Date
  2007-08-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592125
[Presentation] Basic gelatin hydrogels enhances the effect of mutant BMP-22007
- Author(s)
  K., Shimono, M., Oshima, K., Nawachi, M., Kanyama, W., Sebald, Y., Tabata, K., Sugama, T., Kuboki
- Organizer
  Summer School, Japanese Prosthodontic Society Chugoku-Shikoku Branch
- Place of Presentation
  Tokushima(Naruto)
- Year and Date
  2007-08-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592125

1. KUBOKI Takuo (00225195)

# of Collaborated Projects: 9 results

# of Collaborated Products: 13 results
2. KANYAMA Manabu (90294420)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. ONO MITSUAKI (60613156)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. SONOYAMA Wataru (40325121)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 大野彩 (20584626)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. ARAKAWA Hikaru (30304314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SEIYA Yamasaki (40444666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OIDA Yasutaka (50625720)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. AKIYAMA KENTARO (70423291)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SHINKAWA SHIGEHIKO (10727465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UEHARA Junji (10379836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小島俊司 (10346455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 藤澤拓生 (20325096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 納所秋二 (40884797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KIMURA Aya

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
16. MINAKUCHI Mami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 李起学

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

NAWACHI KUMIKO 縄稚 久美子

NAWACHI Kumiko 縄稚 久美子

Research Projects

Research Products

Co-Researchers

時空間的トランスクリプトーム解析を応用した歯肉角化制御メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bone marrow microenvironment of MRONJ and application of Escherichia coli derived BMP-2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bone regenerative therapy using Escherichia coli-derived rhBMP-2 adsorbed in beta-TCP.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism identification of environmental selective bone induction/suppression of BMP-2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanisms involving BMP-2-induced inhibition of bone formation or niche formation at the bone marrow microenvironment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

第二世代BMP-2を応用した口腔インプラントの骨結合促進と歯槽骨再生の実用化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bone regeneration with degradable hydrogels and genetically modified, recombinant human BMP-2 with two additional repeats of the heparin-binding domain.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of chair-side assay system for ongoing bone loss with peri-implant sulcus fluids

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

自己骨髄由来間葉系幹細胞にタンパク質導入法を応用した歯槽骨再生技術の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 補綴臨床別冊 保険適用新技術完全マスター！ 第4章 口腔内装置 挿管時の歯の保護2018

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Suppression of Bone Necrosis around Tooth Extraction Socket in a MRONJ-like Mouse Model by E-rhBMP-2 Containing Artificial Bone Graft Administration2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] BMP-2/β-TCP Local Delivery for Bone Regeneration in MRONJ-Like Mouse Model2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loss of oral self-care ability results in higher risk of pneumonia in older inpatients: A prospective cohort study in a Japanese rural hospital.2019

Author(s)

Journal Title

DOI

Data Source

NAWACHI KUMIKO 縄稚久美子

NAWACHI Kumiko 縄稚久美子

[Book] 補綴臨床別冊　保険適用新技術完全マスター！　第4章　口腔内装置　挿管時の歯の保護2018