OBI Tomokazu 小尾智一

… Alternative Names

小尾智一オビトモカズ

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Researcher Number	10393117
External Links
Affiliation (Current)	2025: 独立行政法人国立病院機構(静岡・てんかん神経医療センター臨床研究部), その他部局等, その他
Affiliation (based on the past Project Information) *help	2020 – 2023: 独立行政法人国立病院機構(静岡・てんかん神経医療センター臨床研究部), その他部局等, その他 2005: Shioka Institute of Epilepsy and Neurological Disorders, Department of Research, Researcher, てんかん神経医療センター臨床研究部)・遺伝子生化学研究室, 室員 2005: 独立行政法人国立病院機構静岡てんかん, 神経医療センター・臨床研究部・遺伝子生化学研究室, 室員
Review Section/Research Field	Except Principal Investigator Basic Section 52020:Neurology-related / Neurology
Keywords	Except Principal Investigator 神経炎症 / ミトコンドリア / PET / レビー小体型認知症 / GluRε2 / DRPLA / アルツハイマー病（AD) / レビー小体型認知症（DLB) / シナプス機能 / アルツハイマー病 … More / ミクログリア / タウ / cortex cerebellar atrophy / multiple system atrophy / neuronal death / GluRδ / spinocerebellar degeneration / 小脳失調と毛細血管拡張を伴う免疫不全症 / オプソクローヌス・ミオクローヌス症候群 / 自己免疫 / グルタミン酸受容体 / 脳幹脳炎 / 慢性小脳炎 / 皮質小脳萎縮症 / 多系統萎縮症 / 神経細胞死 / GluRδ2 / 脊髄小脳変性症 Less

神経生存とシナプス密度から捉えるレビー小体型認知症とアルツハイマー病の早期病態
- Principal Investigator
  
  寺田達弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
mitochondrial dysfunction and neuroinflammation in early stage of dementia with Lewy bodies disease
- Principal Investigator
  
  Terada Tatsuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
Autoimmunity against Glutamate receptor δ2 in patients with pinocerebellar degeneration
- Principal Investigator
  
  MIZOGUCHI Koichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Shizuoka Institute of Epilepsy and Neurological Disorders

All 2024 2023 2022 2021 2020 2004

All Journal Article Presentation

[Journal Article] Neuroinflammation following anti-parkinsonian drugs in early Parkinson’s disease: a longitudinal PET study2024
- Author(s)
  Terada Tatsuhiro、Bunai Tomoyasu、Hashizume Takanori、Matsudaira Takashi、Yokokura Masamichi、Takashima Hirotsugu、Konishi Takashi、Obi Tomokazu、Ouchi Yasuomi
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 4708-4708
- DOI
  10.1038/s41598-024-55233-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15726, KAKENHI-PROJECT-23K14750, KAKENHI-PROJECT-21KK0143, KAKENHI-PROJECT-23K06943, KAKENHI-PROJECT-22H04923
[Journal Article] Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer's disease2022
- Author(s)
  Tatsuhiro Terada, Joseph Therriault, Min Su Peter Kang, Melissa Savard, Tharick Ali Pascoal, Firoza Lussier, Cecile Tissot, Yi-Ting Wang, Andrea Benedet, Takashi Matsudaira, Tomoyasu Bunai, Tomokazu Obi, Hideo Tsukada, Yasuomi Ouchi, Pedro Rosa-Neto
- Journal Title
  
  Mol Neurodegener
  
  Volume: 16 Issue: 1 Pages: 28-28
- DOI
  10.1186/s13024-021-00448-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19792, KAKENHI-PROJECT-20H03600, KAKENHI-PROJECT-20K07901, KAKENHI-PROJECT-21KK0143, KAKENHI-PROJECT-16H06277
[Journal Article] Mitochondrial complex I abnormalities underlie neurodegeneration and cognitive decline in Alzheimer’s disease2022
- Author(s)
  Terada Tatsuhiro、Therriault Joseph、Kang Min Su、Savard Melissa、Pascoal Tharick Ali、Lussier Firoza、Tissot Cecile、Wang Yi‐Ting、Benedet Andrea、Poltronetti Nina Margherita、Ottoy Julie、Arias Jaime、Frenandez、Bezgin Gleb、Matsudaira Takashi, et al.
- Journal Title
  
  European Journal of Neurology
  
  Volume: 29 Issue: 5 Pages: 1324-1334
- DOI
  10.1111/ene.15246
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15726, KAKENHI-PROJECT-21KK0143, KAKENHI-PROJECT-20H03600, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-20K07901
[Journal Article] Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease2021
- Author(s)
  Terada T, Joseph T, Min Su Peter K, Melissa S, Tharick P, Firoza L, Cecile T, Yi-Ting W, Andrea B, Matsudaira T, Bunai T, Obi T, Tsukada H, Ouchi Y*, Pedro R*
- Journal Title
  
  Mol Neurodegener
  
  Volume: accepted
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07901
[Journal Article] In vivo mitochondrial and glycolytic impairments in patients with Alzheimer disease2020
- Author(s)
  Terada T, Obi T, Bunai T, Matsudaira T, Yoshikawa E, Ando I, Futatsubashi M, Tsukada H, Ouchi Y
- Journal Title
  
  Neurology
  
  Volume: in press Issue: 15 Pages: 1592-1604
- DOI
  10.1212/wnl.0000000000009249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09797, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20K07901, KAKENHI-ORGANIZER-16H06400, KAKENHI-PLANNED-16H06402, KAKENHI-PROJECT-20H03600
[Journal Article] Multiple system atrophy(MSA)症例における夜間無呼吸の検討2004
- Author(s)
  小尾智一, 溝口功一, ほか
- Journal Title
  
  自律神経 41
  
  Pages: 150-154
- NAID
  10013353960
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590859
[Presentation] アルツハイマー病においてミトコンドリア障害はタウ沈着と相関する2023
- Author(s)
  寺田達弘、Joseph Therriault、松平敬史、武内智康、高嶋浩嗣、小尾智一、塚田秀夫、Pedro Rosa-Neto、尾内康臣
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06943
[Presentation] 早期パーキンソン病におけるゾニサミドの神経保護効果：分子イメージングに基づく3年間縦断的検討2023
- Author(s)
  寺田達弘、武内智康、橋爪孝典、松平敬史、横倉正倫、高嶋浩嗣、小西高志、小尾智一、尾内康臣
- Organizer
  MDSJ2023
- Data Source
  KAKENHI-PROJECT-23K06943
[Presentation] Mitochondrial dysfunction is associated with cognitive decline in Alzheimer’s disease2023
- Author(s)
  寺田達弘、Joseph Therriault、:松平敬史、:武内智康、高嶋浩嗣、小渡貴司、川口典彦、荒木保清、小尾智一、塚田秀夫、Pedro Rosa-Neto、尾内康臣
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06943
[Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2023
- Author(s)
  T TERADA, J Therriault, T Matsudaira, T Bunai, H Takashima, N Kawaguchi, T Obi, H Tsukada, Pedro Rosa-Neto, Y Ouchi
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K06943
[Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2023
- Author(s)
  Tatsuhiro TERADA, Joseph Therriault, Takashi Matsudaira, Tomoyasu Bunai, Hirotsugu Takashima, Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi
- Organizer
  19th conference of peace throught MindBrain science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] 早期パーキンソン病においてゾニサミドは側坐核の神経変性を抑制する2023
- Author(s)
  寺田達弘、武内智康、橋爪孝典、松平敬史、横倉正倫、高嶋浩嗣、小西高志、小尾智一、尾内康臣
- Organizer
  第41回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06943
[Presentation] パーキンソン病の前頭葉機能障害と行動障害は脳萎縮と相関する2023
- Author(s)
  寺田達弘、宮田淳、久保田学、松平敬史、高嶋浩嗣、川口典彦、荒木保清、尾内康臣、小尾智一、村井俊哉
- Organizer
  第47回日本神経心理学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06943
[Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2023
- Author(s)
  Tatsuhiro TERADA, Joseph Therriault, Takashi Matsudaira, Tomoyasu Bunai,Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi.
- Organizer
  The 20th Kyungpook-Hamamatsu Joint Medical Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06943
[Presentation] パーキンソン病の前頭葉機能障害は脳萎縮と相関する2023
- Author(s)
  寺田達弘、宮田淳、久保田学、吉住美穂、松平敬史、高嶋浩嗣、川口典彦、荒木保清、尾内康臣、小尾智一、村井俊哉
- Organizer
  第25回日本ヒト脳機能マッピング学会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] 早期パーキンソン病におけるゾニサミドの神経保護効果の評価：PETによる3年間の追跡検討2022
- Author(s)
  寺田達弘、横倉正倫、武内智康、松平敬史、高嶋浩嗣、小西高志、小尾智一、尾内康臣
- Organizer
  第24 回日本ヒト脳機能マッピング学会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] Anti-neuroinflammation effect of zonisamide in early Parkinson’s disease: A chronological PET study2022
- Author(s)
  Tatsuhiro Terada, Tomoyasu Bunai, Takashi Matsudaira, Masamichi Yokokura, Hirotsugu Takashima, Takashi Konishi, Tomokazu Obi, Yasuomi Ouchi
- Organizer
  第６３回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2022
- Author(s)
  Tatsuhiro TERADA, Joseph Therriault, Takashi Matsudaira, Tomoyasu Bunai, Hirotsugu Takashima, Norihiko Kawaguchi, Yasukiyo Araki, Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi
- Organizer
  BRAIN CONNECT2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] アルツハイマー病のミトコンドリア障害は糖代謝、脳萎縮、認知機能障害と関連する2022
- Author(s)
  寺田達弘、Joseph Therriault、:松平敬史、:武内智康、高嶋浩嗣、川口典彦、荒木保、小尾智一、塚田秀夫、Pedro Rosa-Neto、尾内康臣
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] Mitochondrial dysfunction underlie neurodegeneration in Alzheimer’s disease: A PET study2022
- Author(s)
  Tatsuhiro Terada, Joseph Therriault, Min Su Kang, Tharick Ali Pascoal, Gleb Bezgin, Takashi Matsudaira, Tomoyasu Bunai, Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi
- Organizer
  13th congress of the world federation of nuclear medicine and biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] Mitochondrial complex I abnormalities is associated with tau pathology in Alzheimer’s disease2022
- Author(s)
  Tatsuhiro TERADA, Joseph Therriault, Min Su Kang, Takashi Matsudaira, Tomoyasu Bunai, Hirotsugu Takashima, Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] 早期パーキンソン病におけるゾニサミドの神経保護効果の評価：PETによる3年間の追跡検討2022
- Author(s)
  寺田達弘、横倉正倫、武内智康、松平敬史、高嶋浩嗣、小西高志、小尾智一、尾内康臣、
- Organizer
  第24 回日本ヒト脳機能マッピング学会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] 早期パーキンソン病におけるゾニサミドの神経保護効果：分子画像に基づく縦断的検討2022
- Author(s)
  寺田達弘、武内智康、橋爪孝典、松平敬史、横倉正倫、高嶋浩嗣、小西高志、小尾智一、尾内康臣
- Organizer
  第40回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease2022
- Author(s)
  寺田達弘、Joseph Therriault、:松平敬史、:武内智康、高嶋浩嗣、川口典彦、荒木保清、小尾智一、Pedro Rosa-Neto、尾内康臣
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] Complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer's disease2021
- Author(s)
  寺田達弘， Joseph Therriault， Min Su Peter Kang，松平敬史，武内智康，小尾智一，高嶋浩嗣，川口典彦，荒木保清，塚田秀夫， Pedro Rosa-neto，尾内康臣
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] In vivo association of mitochondrial dysfunction with tau pathology in early Alzheimer’s disease2020
- Author(s)
  Terada T, Joseph T, Min Su Peter K, Melissa S, Tharick Pascoal, Firoza L, Cecile T, Yi-Ting W, Andrea B, Matsudaira T, Bunai T, Obi T, Yoshiksawa E, Ando I, Futatsubashi M, Tsukada H, Ouchi Y, Pedro R
- Organizer
  第44回日本神経科学会大会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] In vivo mitochondrial and glycolytic impairments in Alzheimer's disease2020
- Author(s)
  寺田達弘、小尾智一、武内智康、松平敬史、安藤一郎、二ツ橋正美、塚田秀夫、川口典彦、荒木保清、尾内康臣
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] アルツハイマー病におけるミトコンドリアと解糖系障害　PETによる検討2020
- Author(s)
  寺田達弘、小尾智一、武内智康、松平敬史、高嶋博嗣、川口典彦、荒木保清、塚田秀夫、尾内康臣
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07901
[Presentation] アルツハイマー病におけるミトコンドリアと解糖系障害の関連2020
- Author(s)
  寺田達弘, Joseph T, Min Su Peter K, Tharick P, 松平敬史, 武内智康, 小尾智一, 塚田秀夫, Pedro R, 尾内康臣
- Organizer
  第60回日本核医学学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07901

1. Terada Tatsuhiro (80550178)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
2. 武内智康 (20754188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
3. 尾内康臣 (40436978)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
4. MIZOGUCHI Koichi (50190666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. TAKAHASHI Yukitoshi (70262764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TANAKA Masaki (90360809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 横倉正倫 (00529399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 松平敬史 (80743210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results

OBI Tomokazu 小尾 智一

小尾 智一 オビ トモカズ

Research Projects

Research Products

Co-Researchers

神経生存とシナプス密度から捉えるレビー小体型認知症とアルツハイマー病の早期病態

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

mitochondrial dysfunction and neuroinflammation in early stage of dementia with Lewy bodies disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Autoimmunity against Glutamate receptor δ2 in patients with pinocerebellar degeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Neuroinflammation following anti-parkinsonian drugs in early Parkinson’s disease: a longitudinal PET study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer's disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial complex I abnormalities underlie neurodegeneration and cognitive decline in Alzheimer’s disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease2021

Author(s)

Journal Title

Data Source

[Journal Article] In vivo mitochondrial and glycolytic impairments in patients with Alzheimer disease2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiple system atrophy(MSA)症例における夜間無呼吸の検討2004

Author(s)

Journal Title

NAID

Description

Data Source

[Presentation] アルツハイマー病においてミトコンドリア障害はタウ沈着と相関する2023

Author(s)

Organizer

Data Source

[Presentation] 早期パーキンソン病におけるゾニサミドの神経保護効果：分子イメージングに基づく3年間縦断的検討2023

Author(s)

Organizer

Data Source

[Presentation] Mitochondrial dysfunction is associated with cognitive decline in Alzheimer’s disease2023

Author(s)

Organizer

Data Source

[Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2023

Author(s)

Organizer

Data Source

[Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2023

Author(s)

Organizer

Data Source

[Presentation] 早期パーキンソン病においてゾニサミドは側坐核の神経変性を抑制する2023

Author(s)

Organizer

Data Source

[Presentation] パーキンソン病の前頭葉機能障害と行動障害は脳萎縮と相関する2023

Author(s)

Organizer

OBI Tomokazu 小尾智一

小尾智一オビトモカズ

[Presentation] アルツハイマー病におけるミトコンドリアと解糖系障害　PETによる検討2020