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Ishizaki Yoshimasa  石崎 仁將

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ISHIZAKI Yoshimasa  石崎 仁將

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Researcher Number 10414103
Other IDs
Affiliation (Current) 2025: 公益財団法人微生物化学研究会, 微生物化学研究所, 主任研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 公益財団法人微生物化学研究会, 微生物化学研究所, 主任研究員
2016: (公財)微生物化学研究会, 微生物化学研究所 第2生物活性研究部, 主任研究員
2014 – 2015: 公益財団法人微生物化学研究会, 微生物化学研究所, 主任研究員
Review Section/Research Field
Principal Investigator
Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 38020:Applied microbiology-related / Applied biochemistry
Except Principal Investigator
Drug development chemistry
Keywords
Principal Investigator
薬剤耐性グラム陰性細菌 / 天然由来化合物 / 作用機序解析 / グラム陰性細菌 / 抗菌活性化合物 / DNA配列の増幅 / 生合成遺伝子 / 放線菌 / 抗生物質 / caprazamycin高生産 … More / 遺伝子クラスター増幅 / 抗生物質高生産 / ZouA法 / 遺伝子増幅 / 分子育種 / アラビノガラクタン生合成 / WecA阻害 / arabinogalactan ligase / WecA / 新規抗結核薬 / CPZEN-45 / 作用機序の同定 … More
Except Principal Investigator
構造活性相関 / 抗結核薬 / XDR-TB / ケミカルバイオロジー / 触媒的不斉合成 Less
  • Research Projects

    (4 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (5 People)
  •  作用機序未知の抗細菌活性を有する天然化合物群の解析と新しい評価系の構築Principal Investigator

    • Principal Investigator
      石崎 仁將
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Microbial Chemistry Research Foundation
  •  Establishment of Molecular Breeding Method (ZouA Amplification) Using the Mechanism of Kanamycin-Producing ActinomycetesPrincipal Investigator

    • Principal Investigator
      ISHIZAKI Yoshimasa
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38020:Applied microbiology-related
    • Research Institution
      Microbial Chemistry Research Foundation
  •  Mode of action study of a novel antituberculous agent CPZEN-45Principal Investigator

    • Principal Investigator
      ISHIZAKI Yoshimasa
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied biochemistry
    • Research Institution
      Microbial Chemistry Research Foundation
  •  Development of anti-XDR-TB leads based on catalytic asymmetric synthesis and chemical biology

    • Principal Investigator
      WATANABE Takumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Microbial Chemistry Research Foundation

All 2023 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] Cycloimidamicins, Novel natural lead compounds for translation inhibition in Pseudomonas aeruginosa2023

    • Author(s)
      Ishizaki Yoshimasa、Umekita Maya、Arisaka Rie、Hatano Masaki、Kimura Tomoyuki、Kubota Yumiko、Shibuya Yuko、Hayashi Chigusa、Sawa Ryuichi、Igarashi Masayuki
    • Journal Title

      The Journal of Antibiotics

      Volume: 76 Issue: 12 Pages: 691-698

    • DOI

      10.1038/s41429-023-00656-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K06191
  • [Presentation] 新規抗生物質 cyclomidamicin 類の構造活性相関に関する研究2023

    • Author(s)
      駒形 万喜子, 阿部 光, 梅北 まや, 次田 篤史, 石崎 仁將, 有坂 理恵, 波多野 和樹, 木村 智之, 澤 竜一, 田中 良和, 横山 武司, 渡辺 匠, 五十嵐 雅之
    • Organizer
      日本放線菌学会 第37回大会
    • Data Source
      KAKENHI-PROJECT-23K06191
  • [Presentation] CPZEN-45; a promising drug candidate for treating extremely drug-resistant tuberculosis (XDR-TB): synthesis, activity, and mode of action2016

    • Author(s)
      Yoshimasa Ishizaki, Kazushige Sasaki, Yoshiaki Takahashi, Masayuki Igarashi, Toshiaki Miyake, Masaji Okada, Norio Doi, Patrick J. Brennan, Yuzuru Akamatsu, Akio Nomoto, and Masakatsu Shibasaki
    • Organizer
      2016 Colorado Mycobacteria Conference
    • Place of Presentation
      アメリカ合衆国、コロラド州
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26870829
  • [Presentation] CPZEN-45, As a Promising Drug Candidate for Treating Extremely Drug-Resistant Tuberculosis (XDR-TB): Synthesis, Activity and Mode of Action2015

    • Author(s)
      Kazushige Sasaki, Yoshimasa Ishizaki, Yoshiaki Takahashi, Masayuki Igarashi, Toshiaki Miyake, Masaji Okada, Norio Doi, Patrick J. Brennan, Yuzuru Akamatsu, Akio Nomoto
    • Organizer
      International Symposium for Medicinal Sciences(日本薬学会第135年会)
    • Place of Presentation
      兵庫医療大学 オクタホール(神戸)
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26870829
  • [Presentation] A Semisynthetic Antitubercular Agent CPZEN-45 Inhibits the GlcNAc-1-phosphate Transferase WecA, Involved in Mycobacterial Arabinogalactan Biosynthesis2014

    • Author(s)
      Yoshimasa Ishizaki, Venugopal Pujari, Chigusa Hayashi, Kunio Inoue, Masayuki Igarashi, Yoshiaki Takahashi, Dean C. Crick, Patrick J. Brennan, Akio Nomoto
    • Organizer
      54th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Place of Presentation
      Walter E. Washington convention center(米国)
    • Year and Date
      2014-09-09
    • Data Source
      KAKENHI-PROJECT-26870829
  • 1.  WATANABE Takumi (80270544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  UMEZAWA Yoji (60160313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  SAKAMOTO Shuichi (60346070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Gandamala Ravi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Wang Lu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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