Hashimoto-tane Akiko 多根彰子

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橋本彰子

HASHIMOTO-TANE Akiko 多根彰子(橋本彰子)

TANE Akiko 多根彰子

橋本彰子ハシモトアキコ

多根彰子(橋本彰子) タネアキコ

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Researcher Number	10415226
Affiliation (based on the past Project Information) *help	2018: 国立研究開発法人理化学研究所, 生命医科学研究センター, 上級研究員 2016 – 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 上級研究員 2015: 国立研究開発法人理化学研究所, 統合生命医科学センター, 研究員 2013 – 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, 研究員 2008 – 2012: The Institute of Physical and Chemical Research, 免疫シグナル研究グループ, 研究員 2007: The Institute of Physical and Chemical Research, 免疫シグナル研究グループ, 研究員 2006: 独立行政法人理化学研究所, 検疫シグナル研究グループ, 研究員
Review Section/Research Field	Principal Investigator Immunology Except Principal Investigator Immunology
Keywords	Principal Investigator 蛍光イメージング / 免疫シナプス / T細胞 / 受容体シグナル / T細胞受容体 / 免疫学 / 基礎医学 / ネガティブフィードバック / T細胞受容体シグナル / 自己免疫 … More / GWAS / 脱リン酸化酵素 / 抗原受容体シグナル / 自己免疫性疾患 / モーター分子 / アクチン / シグナル伝達 / 免疫 / ミオシンII / 免疫シグナル / 全反射顕微鏡 / ミオシン / インテグリン / 受容体クラスター / T細胞抗原受容体 / 細胞骨格 / T 細胞抗原受容体 / FRET / ラフト / 細胞 … More Except Principal Investigator 抗原認識 / 免疫シナプス / イメージング解析 / シグナル伝達 / ミクロクラスター / 立体構造解析 / T細胞活性化 / 構造解析 / 細胞活性化 / TCR-CD3複合体 / T細胞 Less

Functional analysis of autoimmune-associating phosphatases in T cellPrincipal Investigator
- Principal Investigator
  
  Hashimoto-tane Akiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Institute of Physical and Chemical Research
Spatiotemporal and structural analysis of T cell activation regulation
- Principal Investigator
  
  Saito Takashi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Immunology
- Research Institution
  Institute of Physical and Chemical Research
T細胞活性化の時空間的制御の解析
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
The microsynapse is an essential structure for T cell activationPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO-TANE Akiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Analysis of immunological synapse in physiological conditionPrincipal Investigator
- Principal Investigator
  
  TANE Akiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Spaciotemporal analysis of TCR microcluster and lipid raft on T cell activationPrincipal Investigator
- Principal Investigator
  
  TANE Akiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] 臨床免疫・アレルギー科2013
- Author(s)
  多根（橋本）彰子
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24590591
[Book] 感染・炎症・免疫2012
- Author(s)
  多根（橋本）彰子、斉藤　隆.
- Total Pages
  4
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24590591
[Journal Article] Inhibition of T cell activation and function by the adaptor protein CIN85.2019
- Author(s)
  Kong Mei S*., Hashimoto-Tane A*., Kawashima Y., Sakuma M., Yokosuka T., Kometani K., Onishi R., Carpino N., Ohara O., Kurosaki T., Phua K.K. and Saito, T.
- Journal Title
  
  Science Signaling
  
  Volume: 12 Issue: 567 Pages: 1609-1625
- DOI
  10.1126/scisignal.aav4373
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19576, KAKENHI-PROJECT-18K19447, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PUBLICLY-17H05806, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-17H03600, KAKENHI-PROJECT-18H02672, KAKENHI-PROJECT-16K08851
[Journal Article] Analyzing the Dynamics of Signaling Microclusters2017
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Saito T.
- Journal Title
  
  The Immune Synapse
  
  Volume: 1584 Pages: 5-64
- DOI
  10.1007/978-1-4939-6881-7_4
- ISBN
  9781493968794, 9781493968817
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08851, KAKENHI-PROJECT-17K19576, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-24229004, KAKENHI-ORGANIZER-16H06495, KAKENHI-PUBLICLY-17H05806
[Journal Article] TCRマイクロクラスター，マイクロリングと T 細胞活性化2017
- Author(s)
  多根(橋本)彰子
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 67(3) Pages: 295-301
- Data Source
  KAKENHI-PROJECT-16K08851
[Journal Article] Dynamic regulation of TCR-microclusters and the microsynapse for T cell activation.2016
- Author(s)
  Hashimoto-Tane A., Saito T.
- Journal Title
  
  Frontiers Immunology
  
  Volume: 7(255) Pages: 1-8
- DOI
  10.3389/fimmu.2016.00255
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08851
[Journal Article] Micro adhesion rings surrounding TCR microclusters are essential for T cell activation2016
- Author(s)
  Akiko Hashimoto-Tane, Machie Sakuma, Hiroshi Ike, Tadashi Yokosuka, Yayoi Kimura, Osamu Ohara, Takashi Saito
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229004
[Journal Article] Dynamic regulation of TCR-microcluster and microsynapse for T cell activation2016
- Author(s)
  Hashimoto-Tane A., Yokosuka T. and Saito T.
- Journal Title
  
  Front. Immunol.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24229004
[Journal Article] Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation2016
- Author(s)
  Hashimoto-Tane A, Sakuma M, Ike H, Yokosuka T, Kimura Y, Ohara O, Saito T.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 213 Issue: 8 Pages: 1609-1625
- DOI
  10.1084/jem.20151088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PROJECT-16K08851, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-16H05230
[Journal Article] Nucleic acid sensing by T cells initiates Th2 cell differentiation.2014
- Author(s)
  Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T
- Journal Title
  
  Nat Commun
  
  Volume: 10 Issue: 1 Pages: 3566-3566
- DOI
  10.1038/ncomms4566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24790489, KAKENHI-PROJECT-26293107, KAKENHI-PROJECT-26670236
[Journal Article] Nucleic acid sensing by T cells initiates Th2 cell differentiation.2014
- Author(s)
  Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T.
- Journal Title
  
  Nature Communications
  
  Volume: 5 Pages: 3566-3566
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590591
[Journal Article] Programmed cell death-1 forms negative costimulatorymicroclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP22012
- Author(s)
  Yokosuka T, Takamatsu M, Kobayashi-Imanishi W, Hashimoto-Tani A, Azuma M, Saito T
- Journal Title
  
  J Exp Med
  
  Volume: 209 Issue: 6 Pages: 935-945
- DOI
  10.1084/jem.20112741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249082, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24590590, KAKENHI-PROJECT-24590591, KAKENHI-PUBLICLY-23113521
[Journal Article] Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation2011
- Author(s)
  Akiko Hashimoto-Tane, Tadashi Yokosuka, Kumiko Sakata-Sogawa, Machie Sakuma, Chitose Ishihara, Makio Tokunaga, Takashi Saito
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 919-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790486
[Journal Article] T cell receptor-microclusters critical for T-cell activation are formed independently of lipid raft clustering.2010
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W, Saito, T
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 30(14) Pages: 3421-3429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790486
[Journal Article] Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters2010
- Author(s)
  Saito, T, Yokosuka, T. and Hashimoto-Tane, A
- Journal Title
  
  FEBS Letters
  
  Volume: 584 Pages: 4865-4871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790486
[Journal Article] Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters.2010
- Author(s)
  Saito, T, Yokosuka, T., Hashimoto-Tane, A
- Journal Title
  
  FEBS Letters
  
  Volume: 584 Pages: 4865-4871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790486
[Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation.2010
- Author(s)
  Yokosuka, T, Kobayashi, W, Takamatsu, M, Sakata-Sogawa, K, Zeng, H, Hashimoto-Tane, A, Yagita, H, Tokunaga, M, Saito, T
- Journal Title
  
  Immunity
  
  Volume: 33(3) Pages: 326-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790486
[Journal Article] Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation2010
- Author(s)
  Yokosuka, T, Kobayashi, W, Takamatsu, M, Sakata-Sogawa, K, Zeng, H, Hashimoto-Tane, A, Yagita, H, Tokunaga, M, Saito, T
- Journal Title
  
  Immunity
  
  Volume: 33(3) Pages: 326-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790486
[Journal Article] T cell receptor-microclusters critical for T-cell activation are formed independently of lipid raft clustering2010
- Author(s)
  Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W and Saito, T
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 30 (14) Pages: 3421-3429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790486
[Journal Article] Spatiotemporal regulation of T cell co-stimulation by TCR-CD28 microclusters through PKCθtranslocation2008
- Author(s)
  Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T.
- Journal Title
  
  Immunity Vol.29
  
  Pages: 589-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Molecular assembly and function of PTPN22 in T cell receptor signaling2018
- Author(s)
  Akiko Hashimoto-tane
- Organizer
  FASEB Immunoreceptors and Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08851
[Presentation] Functional analysis of autoimmune-associated phosphatase PTPN2(TCPTP) in T cells2018
- Author(s)
  Akiko Hashimoto-tane
- Organizer
  2018 Annual Meeting of Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-16K08851
[Presentation] Function of autoimmune-related phosphatase PTPN22 in T cell signaling2017
- Author(s)
  HASHIMOTO-TANE Akiko, Takashi Saito
- Organizer
  日本薬理学会年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市)
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08851
[Presentation] Molecular assembly and function of PTPN22 in T cell receptor signaling2017
- Author(s)
  Akiko Hashimoto-Tane and Takashi Saito
- Organizer
  2017 Annual Meeting of Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-16K08851
[Presentation] Molecular assembly and function of PTPN22 in T cell receptor signaling2017
- Author(s)
  Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] TCR signaling introduces endocytic machinaries at the microclusters2017
- Author(s)
  Hiroaki Machiyama, Kikumi Hata, Noriko Yanase, Akiko Hashimoto-Tane, Takashi Saito, Ei Wakamatsu, Tadashi Yokosuka
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Adhesion-ring surrounding each TCR microcluster forms synapse-like structure essential for initial T cell activation2016
- Author(s)
  Akiko Hashimoto-Tane, Machie Sakuma, Hiroshi Ike, Tadashi Yokosuka, Takashi Saito
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Function of autoimmune-related phosphatase PTPN22 in T cell signaling2016
- Author(s)
  HASHIMOTO-TANE Akiko, Takashi Saito
- Organizer
  2016 Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄コンベンションセンター(沖縄県宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K08851
[Presentation] Micro adhesion rings surrounding TCR microclusters are essential for T cell activation2016
- Author(s)
  HASHIMOTO-TANE Akiko, Takashi Saito
- Organizer
  EMBO conference
- Place of Presentation
  イタリア、シエナ
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08851
[Presentation] “Microsynapse” composed of focal adhesion molecules surrounding TCR microcluster is essential for T cell activation2015
- Author(s)
  Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  2015 Keystone Symposia Conference
- Place of Presentation
  Snowbird, USA
- Year and Date
  2015-03-30
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015
- Author(s)
  Yokosuka, T., Hashimoto-Tane A., and Saito T.
- Organizer
  第25回Kyoto T Cell Conference (KTCC) 学術集会
- Place of Presentation
  京都大学芝蘭会館（京都府京都市）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] T細胞活性化開始点であるT細胞受容体ミクロクラスターを支える構造体ミクロシナプスの解析2015
- Author(s)
  橋本ー多根彰子、横須賀忠、斉藤隆
- Organizer
  88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] T細胞活性化開始点であるT細胞受容体ミクロクラスターを支える構造体ミクロシナプスの解析2015
- Author(s)
  Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] “Microsynapse” composed of focal adhesion molecules surrounding TCR microcluster is essential for T cell activation2015
- Author(s)
  Hashimoto-Tane, A., Sakuma, M., Yokosuka, T., Saito, T
- Organizer
  2015 Keystone Symposia Conference D3: T Cells: Regulation and Effector Function
- Place of Presentation
  アメリカ、ユタ州、スノーバードリゾート
- Year and Date
  2015-03-30
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] The “Microsynapse” composed of a ring of focal adhesion molecules and a core of T cell receptor microclusters is an essential structure for T cell activation2015
- Author(s)
  Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
- Organizer
  FASEB Science Research Conference
- Place of Presentation
  Big Sky, Montana, USA
- Year and Date
  2015-06-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] The “Microsynapse” composed of a ring of focal adhesion molecules and a core of T cell receptor microclusters is an essential structure for T cell activation2015
- Author(s)
  Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
- Organizer
  The 44th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Cytoskeletal regulation of the clustering of a Ras-GEF, RasGRP1, upon T cell activation2015
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Masae Furuhata, Hiroko Toyota, Takashi Saito
- Organizer
  The 44th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] The Inhibitory role of CIN85 adaptor protein in T cell functions2015
- Author(s)
  Kong, M.S., Hashimoto-Tane A., Yokosuka, T., Kurosaki, T., and Saito, T.
- Organizer
  第25回Kyoto T Cell Conference (KTCC) 学術集会
- Place of Presentation
  京都大学芝蘭会館（京都府京都市）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] The Inhibitory role of CIN85 adaptor protein in T cell functions2015
- Author(s)
  Mei Suen Kong, Akiko Hashimoto-Tane, Tadashi Yokosuka, Tomohiro Kurosaki, Kia Kien Phua, Takashi Saito
- Organizer
  The 44th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Subcellular imaging of the E3 ubiquitin ligases, c-Cbl and Cbl-b, to control T cell activation signals through ubiquitin clustering at TCR microclusters2014
- Author(s)
  Yokosuka, T., Hashimoto-Tane, A., Saito, T
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] “Microsynapse” structure supporting TCR microclusters augments T cell activation2014
- Author(s)
  Akiko Hashimoto-Tane, Tadashi Yokosuka, Takashi Saito
- Organizer
  The 43rd Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] “Microsynapse” structure supporting TCR microclusters augments T cell activation,2014
- Author(s)
  Hashimoto-Tane, A., Yokosuka, T., Saito, T
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] Subcellular imaging of the E3 ubiquitin ligases, c-Cbl and Cbl-b, to control T cell activation signals through ubiquitin clustering at TCR microclusters2014
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito,
- Organizer
  The 43rd Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling2014
- Author(s)
  Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito
- Organizer
  第24回 Kyoto T Cell Conference
- Place of Presentation
  京都大学（京都）
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Arp2/3 complex-mediated actin-nucleation supports T cell receptor microcluster2013
- Author(s)
  Hashimoto-Tane, A., Yokosuka, T., Saito, T
- Organizer
  第42回日本免疫学会
- Place of Presentation
  Makuhari Messe, Chiba
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] Distinct signalosome formation by two Ras-GEFs to activate the Ras-MAPK pathway in T cell signaling2013
- Author(s)
  Yokosuka, T., Hashimoto-Tane, A., Saito, T.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Arp2/3 complex-mediated actin-nucleation supports T cell receptor microcluster2013
- Author(s)
  Hashimoto-Tane, A., Yokosuka, T., Saito, T.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24229004
[Presentation] Negative costimulatory microclusters inhibiting T cell-mediated inflammation2013
- Author(s)
  Yokosuka, T., Hashimoto-Tane, A., Saito, T.
- Organizer
  JST-CREST International Symposium ”Frontiers in Immunology and Inflammation: from Molecules to Disease”
- Place of Presentation
  一橋記念講堂(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] Regulation of T cell receptor signaling by cytoskeletal dynamics2013
- Author(s)
  Hashimoto-Tane, A., Sakuma, M., Yokosuka, T., Saito, T
- Organizer
  The 5th Biennale RIKEN Joint Retreat “Behavior from Molecules, Cells to Organisms
- Place of Presentation
  YAMAHAリゾートつごもり(静岡県掛川市)
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] Dynamic and cytoskeletal regulation of T cell activation2013
- Author(s)
  Saito, T., Yokosuka, T., Hashimoto-Tane, A.
- Organizer
  Michigan-RCAI Joint Workshop
- Place of Presentation
  Detroit, MC USA
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] The movement of T cell receptor signaling molecules2012
- Author(s)
  多根(橋本)　彰子
- Organizer
  実験研究者のための数理生物学サマーレクチャーコース第1回
- Place of Presentation
  理化学研究所(神戸市中央区)
- Data Source
  KAKENHI-PROJECT-24590591
[Presentation] モーター分子ダイニンによるT細胞受容体ミクロクラスター輸送を介した活性化制御2012
- Author(s)
  多根(橋本)彰子
- Organizer
  第21回東京免疫フォーラム
- Place of Presentation
  東京(招待講演)
- Year and Date
  2012-03-08
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] 免疫シナプス形成を担うダイニンによるT細胞抗原受容体運搬の分子機構2012
- Author(s)
  多根(橋本)彰子
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] 免疫シナプス形成を担うダイニンによるT 細胞抗原受容体運搬の分子機構2012
- Author(s)
  多根(橋本)彰子、横須賀忠、斉藤隆
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] モーター分子ダイニンによるT 細胞受容体ミクロクラスター輸送を介した活性化制御2012
- Author(s)
  多根(橋本)彰子
- Organizer
  第21回東京免疫フォーラム
- Place of Presentation
  東京
- Year and Date
  2012-03-08
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] 免疫シナプスにおけるダイニンによるT 細胞ミクロクラスター運搬の分子機構2011
- Author(s)
  多根(橋本)彰子、横須賀忠、斉藤隆
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-driven transport of TCR microclusters forms Immune synapse and regulates T cell activation2011
- Author(s)
  Hashimoto-Tane,A., Yokosuka, T., Sakuma, M. and Saito, T
- Organizer
  The 84th Annual Meeting of The Japanese Pharmacology Society
- Place of Presentation
  on line
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-driven transport of TCR microclusters forms Immune synapse and regulates T cell activation.2011
- Author(s)
  Hashimoto-Tane, A., Yokosuka, T., Sakuma, M., Saito, T.
- Organizer
  The 84^<th> Annual Meeting of The Japanese Pharmacology Society
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] 免疫シナプスにおけるダイニンによるT細胞ミクロクラスター運搬の分子機構2011
- Author(s)
  多根(橋本)彰子
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-driven transport of TCR microclusters forms Immune synapse and regulates T cell activation2010
- Author(s)
  Hashimoto-Tane,A., Saito, T
- Organizer
  The 16th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  東京
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form cSMAC Keystone Symposia2010
- Author(s)
  Hashimoto-Tane,A., Yokosuka, T., Saito, T
- Organizer
  Lymphocyte Activation and Gene Expression
- Place of Presentation
  Breckenridge (USA)
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form cSMAC2010
- Author(s)
  橋本彰子(多根), 横須賀忠, 斉藤隆
- Organizer
  Keystone Symposia Lymphocyte Activation and Gene Expression
- Place of Presentation
  Breckenridge(USA)
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form csmac during T cell activation2010
- Author(s)
  Hashimoto-Tane, Yokosuka, T., Machie Sakuma, Takashi Saito
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-mediated translocation of TCR microclusters along microtubules to form csmac during T cell activation2010
- Author(s)
  Hashimoto-Tane, Yokosuka,T., Machie Sakuma, Takashi Saito
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Dynein-driven transport of TCR microclusters forms Immune synapse and regulates T cell activation2010
- Author(s)
  Hashimoto-Tane, A., Saito, T.
- Organizer
  The 16^<th> Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] TCR microclusters move along microtubules in early T cell activation2009
- Author(s)
  Hashimoto-Tane, A., Yokosuka, T.,Ishihara, C. and Saito, T
- Organizer
  The 5th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  Kyoto
- Year and Date
  2009-06-01
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] TCR microclusters move along microtubules in early T cell activation2009
- Author(s)
  Hashimoto-Tane, A., Yokosuka, T, Ishihara, C., Saito, T.
- Organizer
  The 5^<th> International Workshop of Kyoto T Cell Conference
- Place of Presentation
  Kyoto
- Year and Date
  2009-06-01
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] T細胞活性化及びcSMAC形成につながる微小管モーター・ダイニンによるTCRミクロクラスターの移動2009
- Author(s)
  橋本彰子(多根)、横須賀忠、斉藤隆
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21790486
[Presentation] Mobilization of lipid raft at immunological synapse2008
- Author(s)
  Hashimoto-Tane A, Yokosuka T.,Ishihara C., Saito T.
- Organizer
  第81回日本薬理学会年会
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Mobilization of Lipid raft at Immunological synapse2008
- Author(s)
  多根彰子
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Quantitative analysis of TCR microclusters in CD3ζGFP knock-in T cells2008
- Author(s)
  多根彰子、横須賀忠、斉藤隆
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Identification of a region in immunological synapse critical for T cell co-stimulation2008
- Author(s)
  Yokosuka, T., Sogawa-Sakata, K., Tane-Hashimoto, A., Tokunaga, M., Dustine,ML, Saito T.
- Organizer
  第38回日本免疫学会総会・学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Quantitative analysis of TCR microclusters in CD3zGFP knock-in T cells2008
- Author(s)
  Hashimoto-Tane A., Yokosuka T., Saito T.
- Organizer
  第38回日本免疫学会総会・学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Immunological SynapseにおけるLipid raftの動態2007
- Author(s)
  多根彰子
- Organizer
  第17回Kyoto T Cell Conference (KTCC)学術集会
- Place of Presentation
  京都
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Mobilization of Lipid raft at Immunological Synapse2007
- Author(s)
  Hashimoto-Tane A,Yokosuka T, Saito T
- Organizer
  第37回日本免疫学会総会・学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] TCR-CD28マイクロクラスターによるT細胞活性化の時空間的制御機構2007
- Author(s)
  横須賀忠, 小林若菜, 多根彰子, 十川久美子, 徳永万喜洋, 斉藤隆
- Organizer
  第17回Kyoto T Cell Conference (KTCC)学術集会
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Immunological SynapseにおけるLipid raftの動態2007
- Author(s)
  多根彰子, 横須賀忠, 斉藤隆
- Organizer
  第17回Kyoto T Cell Conference (KTCC)学術集会
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Spatiotemporal regulations of T cell activation by a c-SMAC and TCR-CD28-microclusters2007
- Author(s)
  Yokosuka T.,Sakata-Sogawa K., Hashimoto-Tane A., Tokunaga M., Dustin ML., Saito,T.
- Organizer
  第37回日本免疫学会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] TCRミクロクラスターにおけるリピッドラフトの動態/Mobilization of Lipid raft at Immunological Synapse2007
- Author(s)
  橋本(多根)彰子
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka T. Sakata-Sogawa K. Kobayashi W., Hiroshima M., Hashimoto-Tane A., Tokunaga M., Dustine M.L., Saito T.
- Organizer
  13th International Congress of Immunology
- Year and Date
  2007-08-21
- Data Source
  KAKENHI-PROJECT-18790344
[Presentation] Spatiotemporal regulation of T cell activation by TCR-CD28-microclusters2007
- Author(s)
  Yokosuka T. Sakata-Sogawa K. Kobayashi W., Hiroshima M., Hashimoto-Tane A., Tokunaga M., Dustine M.L., Saito T.
- Organizer
  第7回日本蛋白質科学会年会
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18790344

1. Saito Takashi (50205655)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
2. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 横須賀忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 東みゆき

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto-tane Akiko 多根 彰子

橋本彰子

HASHIMOTO-TANE Akiko 多根 彰子(橋本彰子)

TANE Akiko 多根 彰子

橋本 彰子 ハシモト アキコ

多根 彰子(橋本彰子) タネ アキコ

Research Projects

Research Products

Co-Researchers

Functional analysis of autoimmune-associating phosphatases in T cellPrincipal Investigator

Principal Investigator

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Research Institution

Spatiotemporal and structural analysis of T cell activation regulation

Principal Investigator

Project Period (FY)

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T細胞活性化の時空間的制御の解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The microsynapse is an essential structure for T cell activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of immunological synapse in physiological conditionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Spaciotemporal analysis of TCR microcluster and lipid raft on T cell activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床免疫・ア レルギー科2013

Author(s)

Total Pages

Publisher

Data Source

[Book] 感染・炎症・免疫2012

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Inhibition of T cell activation and function by the adaptor protein CIN85.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analyzing the Dynamics of Signaling Microclusters2017

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] TCRマイクロクラスター，マイクロリングと T 細胞活性化2017

Author(s)

Journal Title

Data Source

[Journal Article] Dynamic regulation of TCR-microclusters and the microsynapse for T cell activation.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Micro adhesion rings surrounding TCR microclusters are essential for T cell activation2016

Author(s)

Journal Title

Data Source

[Journal Article] Dynamic regulation of TCR-microcluster and microsynapse for T cell activation2016

Hashimoto-tane Akiko 多根彰子

HASHIMOTO-TANE Akiko 多根彰子(橋本彰子)

TANE Akiko 多根彰子

橋本彰子ハシモトアキコ

多根彰子(橋本彰子) タネアキコ

[Book] 臨床免疫・アレルギー科2013