Makioka Kouki 牧岡幸樹

… Alternative Names

MAKIOKA Kouki 牧岡幸樹

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Researcher Number	10420176
Other IDs
Affiliation (Current)	2025: 群馬大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2013 – 2016: 群馬大学, 医学部附属病院, 助教
Review Section/Research Field	Except Principal Investigator Neurology
Keywords	Except Principal Investigator タウ / 髄液 / アミロイドβ / アルツハイマー病 / 脳脊髄液 / ユビキチン-プロテアソーム / オートファジー・ライソゾーム / 神経変性疾患 / シアル化 / 神経原線維変化 … More / オートファジー / 顆粒空胞変性 / 後部脳萎縮症 / 原発性進行性失語症 / βアミロイド / アミロイドPET / CSF / microbleeds / Amyloid β / 進行性失語 / 脳血流SPECT / PiB-PET / 大脳皮質微小出血 / 脳アミロイドβ / 神経細胞死 / リン酸化タウ / 遺伝子変異 / プレセニリン Less

Elucidation of cognitive functions and molecular pathogenesis in Alzheimer's disease by CSF and PiB-PET
- Principal Investigator
  
  Ikeda Masaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Gunma University
seeking the role of granulovacuolar degeneration in neurodegeneration
- Principal Investigator
  
  Yamazaki Tsuneo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Gunma University
Analysis of molecular functions of presenilin in CSF phosphorylation of tau
- Principal Investigator
  
  IKEDA MASAKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Gunma University

All 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] An analysis of prognostic factors after percutaneous endoscopic gastronomy palcement in Japansese patients with amyotrophic lateral sclerosis2017
- Author(s)
  Nagashima K, Furuta N, Makioka K, Fujita Y, Ikeda M, Ikeda Y
- Journal Title
  
  J Neurol Sci
  
  Volume: 376 Pages: 202-205
- DOI
  10.1016/j.jns.2017.03.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461264, KAKENHI-PROJECT-16K09665
[Journal Article] Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease2016
- Author(s)
  Makioka K, Yamazaki T, Takatama M, Ikeda M, Murayama S, Okamoto K, Ikeda Y
- Journal Title
  
  Journal of Neurological Sciences
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461304
[Journal Article] Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease.2016
- Author(s)
  Makioka K, Yamazaki T, Takatama M, Ikeda M, Murayama S, Okamoto K, Ikeda Y.
- Journal Title
  
  J Neurol Sci
  
  Volume: 365 Pages: 101-107
- DOI
  10.1016/j.jns.2016.03.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461264, KAKENHI-PROJECT-26461304, KAKENHI-PROJECT-16H06277
[Journal Article] Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains2016
- Author(s)
  Nagamine S, Yamazaki T, Makioka K, Fujita Y, Ikeda M, Takatama M, Okamoto K, Yokoo H, Ikeda Y
- Journal Title
  
  Neuropathology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461304
[Journal Article] Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains.2016
- Author(s)
  Nagamine S, Yamazaki T, Makioka K, Fujita Y, Ikeda M, Takatama M, Okamoto K, Yokoo H, Ikeda Y.
- Journal Title
  
  Neuropathology
  
  Volume: 36 Issue: 4 Pages: 333-345
- DOI
  10.1111/neup.12277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461264, KAKENHI-PROJECT-26461304
[Journal Article] Anti-MuSK Antibody-positive Myasthenia Gravis Mimicking Amyotrophic Lateral Sclerosis2015
- Author(s)
  Furuta N, Ishizawa K, Shibata M, Tsukagoshi S, Nagamine S, Makioka K, Fujita Y, Ikeda M, Yoshimura S, Motomura M, Okamoto K, Ikeda Y.
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 19 Pages: 2497-2501
- DOI
  10.2169/internalmedicine.54.4645
- NAID
  130005101803
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461264, KAKENHI-PROJECT-26461302
[Journal Article] Immunolicalization of Smurf1 in Hirano bodies2014
- Author(s)
  Makioka K, Yamazaki T, Takatama M, Ikeda M, Okamoto K
- Journal Title
  
  J Neurol Sci
  
  Volume: 336 Pages: 24-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591231
[Journal Article] SF levels of Aβ1-38/Aβ1-40/Aβ1-42 and (11)C PiB-PET studies in three clinical variants of primary progressive aphasia and Alzheimer's disease.2014
- Author(s)
  Ikeda M, Tashiro Y, Takai E, Kurose S, Fugami N, Tsuda K, Arisaka Y, KodairaS, Fujita Y, Makioka K, Mizuno Y, Shimada H, Harigaya Y, Takatama M, Amari M, Yamazaki T,Yamaguchi H, Higuchi T, Okamoto K, Tsushima Y, Ikeda Y.
- Journal Title
  
  Amyloid
  
  Volume: 21 Issue: 4 Pages: 238-245
- DOI
  10.3109/13506129.2014.949231
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461264, KAKENHI-PROJECT-26461304
[Journal Article] Immunolocalization of Smurf1 in Hirano bodies.2014
- Author(s)
  Makioka K, Yamazaki T, Takatama M, Ikeda M, Okamoto K
- Journal Title
  
  J Neurol Sci
  
  Volume: 336 Issue: 1-2 Pages: 24-28
- DOI
  10.1016/j.jns.2013.09.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500426, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-26461264, KAKENHI-PROJECT-26461304
[Journal Article] Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis2013
- Author(s)
  Furuta N, Makioka K, Fujita Y, Ikeda M, Takatama M, Matsuoka M, Okamoto K
- Journal Title
  
  Neuropathology
  
  Volume: 33 Issue: 4 Pages: 397-404
- DOI
  10.1111/neup.12010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390059, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24591250
[Journal Article] Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.2013
- Author(s)
  Ikeda M, Yonemura K, Kakuda S, Tashiro Y, Fujita Y, Takai E, Hashimoto Y, Makioka K, Furuta N, Ishiguro K, Maruki R, Yoshida J, Miyaguchi O, Tsukie T, Kuwano R, Yamazaki T, Yamaguchi H, Amari M, Takatama M, Harigaya Y, Okamoto K
- Journal Title
  
  Amyloid
  
  Volume: 20 Issue: 2 Pages: 107-712
- DOI
  10.3109/13506129.2013.790810
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-23500426, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24310144
[Journal Article] CSF phosphorylated tau and Aβ(1-38/1-40/1-42) in Alzheimer's disease with novel PS1 mutations2013
- Author(s)
  Ikeda M, Fujita Y, Makioka K, Yamazaki T, Yamaguchi H
- Journal Title
  
  Amyloid
  
  Volume: 20 Pages: 107-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591231
[Journal Article] Encephalopathy with amyloid angiopathy and numerous amyloid plaques with low levels of CSF Aβ1-40/Aβ1-422012
- Author(s)
  Masaki Ikeda, Kimitoshi Hirayanagi, Motonobu Arai, Satoko Kakuda, Kouki Makioka, Yukio Fujita, Masakuni Amari, Masakitsu Takatama, Yoichi Nakazato, Koichi Okamoto
- Journal Title
  
  Amyloid
  
  Volume: Early online1-5 Issue: 4 Pages: 1350-1356
- DOI
  10.3109/13506129.2012.725113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591231
[Journal Article] Cerebral encephalopathy with amyloid angiopathy and numerous plaques in low levels of CSF Aβ1-40/Aβ1-422012
- Author(s)
  Ikeda M, Makioka K, Okamoto K
- Journal Title
  
  Amyloid
  
  Volume: 19 Pages: 186-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591231
[Journal Article] Activation and alteration of lysosomes in multiple system atrophy2012
- Author(s)
  Makioka K, Yamazaki T, Takatama M, Nakazato Y, Okamoto K
- Journal Title
  
  Neuroreport
  
  Volume: Vol.23 Issue: 5 Pages: 270-276
- DOI
  10.1097/wnr.0b013e3283503e4f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500426, KAKENHI-PROJECT-23591231
[Presentation] Analysis of microbleeds in clinical variants of AD on CSF and Neuroimaging markers.2017
- Author(s)
  Ikeda M, Tashiro Y, Makioka K, Kasahara H, Fujita Y, Nagashima K, Hirayanagi K, Nagamine S, Furuta N, Amari M, Takatama M, Okamoto K, Yamazaki T, Yamaguchi H, Higuchi T, Tsushima Y, Ikeda Y.
- Organizer
  AAIC2016
- Place of Presentation
  トロント（カナダ）
- Year and Date
  2017-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461264
[Presentation] Microbleeds in clinical subtypes of AD on CSF and Neuroimaging markers.2017
- Author(s)
  Ikeda M, Tashiro Y, Makioka K, Kasahara H, Fujita Y, Nagashima K, Hirayanagi K, Nagamine S, Furuta N, Tsukagoshi S, Sekine A, Furuta M, Amari M, Okamoto K, Takatama M, Yamazaki T, Yamaguchi H, Higuchi T, Tsushima Y, Ikeda Y.
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2017-05-20
- Data Source
  KAKENHI-PROJECT-26461264
[Presentation] 脳表ヘモジデリン沈着を呈するADにおけるCSFマーカーと脳画像の臨床的検討．2016
- Author(s)
  池田将樹，笠原浩生，牧岡幸樹，池田佳生．
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26461264
[Presentation] 脳表ヘモジデリン沈着を認めるADにおけるCSFマーカーと脳画像の検討．2016
- Author(s)
  池田将樹，笠原浩生，牧岡幸樹，池田佳生．
- Organizer
  第7回日本脳血管・認知症学会総会Vas-Cog Japan2016
- Place of Presentation
  金沢
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-26461264
[Presentation] Immunolocalization of Tom1 and Tom1-Relating Proteins in Alzheimer’s disease2015
- Author(s)
  Kouki Makioka, Tsuneo Yamazaki, Masamitsu Takatama, Koichi Okamoto, Yoshio Ikeda
- Organizer
  Alzheimer’s Association International Conference 2015
- Place of Presentation
  Washington D.C
- Year and Date
  2015-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461304
[Presentation] Analysis of microbleeds in clinical variants of AD on CSF and Neuroimaging markers.2015
- Author(s)
  Ikeda M, Tashiro Y, Makioka K, Kasahara H, Fujita Y, Nagashima K, Hirayanagi K, Nagamine S, Furuta N, Amari M, Takatama M, Okamoto K, Yamazaki T, Yamaguchi H, Higuchi T, Tsushima Y, Ikeda Y.
- Organizer
  VAS-COG 2015 TOKYO
- Place of Presentation
  TOKYO
- Year and Date
  2015-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461264
[Presentation] Immunolocalization of Tom1 and Tom1-Relating Proteins in Alzheimer’s disease2015
- Author(s)
  Kouki Makioka, Tsuneo Yamazaki, Masamitsu Takatama, Koichi Okamoto, Yoshio Ikeda
- Organizer
  VAS-COG World 2015
- Place of Presentation
  Tokyo
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461304
[Presentation] Relationship between diabetes mellitus and 11C PiB-PET in Alzheimer’s disease.2015
- Author(s)
  Ikeda M, Fujita Y, Nagashima K, Makioka K, Nagamine S, Furuta N, Hirayanagi K, Tsugashi S，Kasahara H, Higuchi T, Tsushima Y, Yoshio Ikeda.
- Organizer
  ICME2015
- Place of Presentation
  Okayama, Japan
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461264
[Presentation] Hirano小体におけるSmurf1の発現について2014
- Author(s)
  牧岡幸樹、山崎恒夫、高玉真光、岡本幸市、池田佳生
- Organizer
  第5回日本血管性認知障害研究会
- Place of Presentation
  京都府京都市
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-26461304
[Presentation] Immunolocalization of Tom1 in Alzheimer’s disease2014
- Author(s)
  Kouki Makioka, Tsuneo Yamazaki, Masamitsu Takatama, Koichi Okamoto, Yoshio Ikeda
- Organizer
  Alzheimer’s Association International Conference 2014
- Place of Presentation
  Copenhagen
- Year and Date
  2014-07-20
- Data Source
  KAKENHI-PROJECT-26461304
[Presentation] osterior cortical atrophyを呈したアルツハイマー病患者の画像的検討2014
- Author(s)
  池田将樹, 田代裕一，藤田行雄，牧岡幸樹，甘利雅邦，高玉真光，岡本幸市，山崎恒夫，山口晴保，池田佳生
- Organizer
  第20回日本脳循環代謝学会総会
- Place of Presentation
  第20回日本脳循環代謝学会総会
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-26461264
[Presentation] Alzheimer病におけるTOM1の発現に関する免疫組織学的検討2014
- Author(s)
  牧岡幸樹、山崎恒夫、高玉真光、岡本幸市、池田佳生
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際センター（福岡県福岡市）
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-26461304
[Presentation] Alzheimer病におけるTom1の発現に関する免疫組織学的検討2014
- Author(s)
  牧岡幸樹、山崎恒夫、高玉真光、岡本幸市、池田佳生
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  パシフィコ横浜　会議センター（神奈川県横浜市）
- Year and Date
  2014-12-01
- Data Source
  KAKENHI-PROJECT-26461304
[Presentation] Cerebral encephalopathy with cerebral amyloid angiopathy and numerous amyloid plaques presenting aberrant low levels of CSF Aβ1-40/1-422012
- Author(s)
  Ikeda M, Hirayanagi K, Arai M, Kakuda S, Makioka K, Furuta N, Kasahara H, Fujita Y, Amari M, Takatama M, Nakazato Y, Okamoto K
- Organizer
  AAIC2012
- Place of Presentation
  カナダ、バンクーバー
- Year and Date
  2012-07-15
- Data Source
  KAKENHI-PROJECT-23591231
[Presentation] Cerebral encephalopathy with cerebral amyloid angiopathy and numerous amyloid plaques presenting aberrant low levels of CSF Aβ-40/1-422012
- Author(s)
  M. Ikeda, K. Hirayanagi, M Arai, S. Kakuda, K. Makioka, N. Furuta, H. Kasahara, Y. Fujita, M. Amari, M. Takatama, Y. Nakazato, K. Okamoto
- Organizer
  AICC2012
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-23591231

1. YAMAZAKI Tsuneo (80200658)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. IKEDA MASAKI (50222899)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. FUJITA Yukio (70420172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. FURUTA Natsumi (80625583)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. 平柳公利 (20701395)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OKAMOTO Koichi (00124652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. SHOJI Mikio (60171021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 池田佳生 (00282400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
9. 山口晴保 (00158114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 対馬義人 (20375546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 長嶺俊 (20719918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 松岡正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 桑野良三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Makioka Kouki 牧岡 幸樹

MAKIOKA Kouki 牧岡 幸樹

Research Projects

Research Products

Co-Researchers

Elucidation of cognitive functions and molecular pathogenesis in Alzheimer's disease by CSF and PiB-PET

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

seeking the role of granulovacuolar degeneration in neurodegeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular functions of presenilin in CSF phosphorylation of tau

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An analysis of prognostic factors after percutaneous endoscopic gastronomy palcement in Japansese patients with amyotrophic lateral sclerosis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease2016

Author(s)

Journal Title

Data Source

[Journal Article] Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains2016

Author(s)

Journal Title

Data Source

[Journal Article] Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-MuSK Antibody-positive Myasthenia Gravis Mimicking Amyotrophic Lateral Sclerosis2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Immunolicalization of Smurf1 in Hirano bodies2014

Author(s)

Journal Title

Data Source

[Journal Article] SF levels of Aβ1-38/Aβ1-40/Aβ1-42 and (11)C PiB-PET studies in three clinical variants of primary progressive aphasia and Alzheimer's disease.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunolocalization of Smurf1 in Hirano bodies.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CSF phosphorylated tau and Aβ(1-38/1-40/1-42) in Alzheimer's disease with novel PS1 mutations2013

Author(s)

Makioka Kouki 牧岡幸樹

MAKIOKA Kouki 牧岡幸樹