zhou wu 武洲

… Alternative Names

武洲タケヒロ

TAKE Hiro 武洲

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Researcher Number	10420598
Other IDs
Affiliation (Current)	2025: 九州大学, 歯学研究院, 准教授
Affiliation (based on the past Project Information) *help	2025: 九州大学, 歯学研究院, 准教授 2022 – 2023: 九州大学, 歯学研究院, 准教授 2016 – 2018: 九州大学, 歯学研究院, 准教授 2012 – 2015: 九州大学, 歯学研究科(研究院), 准教授 2014: 九州大学, 歯学研究院, 准教授 … More 2012: 九州大学, 歯学研究院, 准教授 2010: 九州大学, 歯学研究院, 准教授 2009 – 2010: Kyushu University, 大学院・歯学研究院, 准教授 2008: Kyushu University, 大学院・歯学研究院, 学術研究員 2008: 九州大学, 大学院・歯学研究院, 研究員 2008: 九州大学, 大学院歯学研究院, 研究員 2007: Kyushu University, Faculty of Dental Sciences, Professor 2006: 九州大学, 歯学研究院, 助手 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57020:Oral pathobiological science-related / Pain science Except Principal Investigator Functional basic dentistry / Pathobiological dentistry/Dental radiology / Biological Sciences
Keywords	Principal Investigator 歯周病 / ミクログリア / 髄膜 / 口腔感染学 / アルツハイマー型認知症 / アルツハイマー病 / 髄膜細胞 / 炎症 / 脳バリア / シナプス … More / 脳血管内皮細胞 / 軟膜細胞 / ｐ.gingivalis菌 / 疫学調査 / 口腔健康 / 全身炎症 / 認知機能 / NMDA receotors / patch clamp / glial cells / inflammatory cytokines / leptomeninges / pain / アストロサイト / 下歯槽神経切断 / 三叉神経脊髄路核 / パッチクランプ / NMDA受容体 / パッチリランプ / 炎症性サイトカイン / 三叉神経痛 / パラインフラメーション / TLR2 / pgLPS / 脳炎症 / IL-1 b / 歯周病菌LPS / PGE_2〓 / 密着結合蛋白質 / PGE_2 / 老化 / 未着結合蛋白質 / PGE / アジュバント関節炎 / グリア細胞 / 末梢炎症 / カテプシンB / IL-1β … More Except Principal Investigator ミクログリア / カテプシンB / アジュバント関節炎 / 疼痛炎症 / 炎症疼痛 / M1/M2極性転換 / 分子スイッチ / プロテアーゼ反応 / カテプシン / IL-18 / NF-κB / カスパーゼ-1 / IL-1β / IFN-γ / T細胞 / オートファジー / モルヒネ / 慢性疼痛 / 神経障害性疼痛 / 炎症性疼痛 / クロモグラニンA / カテプシンS / CD44 / ICAM-1 / RANKL / TGF-β1 / プロスタグランジンE2 / リン質リポソーム / アルカリフォスファターゼ / 炎症生骨吸収 / ホスファチジルセリン / 破骨細胞 / 骨芽細胞 / 炎症性骨吸収 / リポソーム / 歯周病 / LPS / 密着結合タンパク質 / 髄膜-グリア / サイトカイン / グリア細胞 / 髄膜 / 脳炎症 / 末梢炎症 / 病者行動 / 長期増強 / パッチクランプ法 / グリシン / HPLC / グリシン結合部位 / NMDA受容体 / 海馬CA1野ニューロン / 脳虚血 / GluR / リアルタイムRT-PCR / 細胞周期 / カイニン酸受容体 / パッチクランプ / dendritic beading / 培養上清 / ATP / synaptic stripping / 神経伝達 / グルタミン酸 Less

ジンジバリス菌の神経血管ユニット破綻を招く機構Principal Investigator
- Principal Investigator
  
  武洲
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Kyushu University
Elucidating new mechanism of brain barrier-synaptic disruptions caused by P. gingivitisPrincipal Investigator
- Principal Investigator
  
  武洲
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Kyushu University
Japan-China Joint Epidemiological Survey of Tibetan Elderly on Correlation between Oral Health and Cognitive FunctionsPrincipal Investigator
- Principal Investigator
  
  Take Hiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Elucidation of Alzheimer's disease exacerbation mechanism of periodontitis centering on microglia-related neuroinflammationPrincipal Investigator
- Principal Investigator
  
  Take Hiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Study on a microglial phenotypic switch with a focus on proteolytic response
- Principal Investigator
  
  Nakanishi Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Critical roles of the chromogranin A-cathepsin B system in a transition of acute pain to a chronic pain state
- Principal Investigator
  
  HIROSHI Nakanishi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Mechanism of the rupture of meningeal-glia limitans during chronic PeriodontitisPrincipal Investigator
- Principal Investigator
  
  TAKE Hiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Inhibition of bone destruction by phosphatidylserine-containing liposomes based on t he regulation of phagocytes functions
- Principal Investigator
  
  HIROSHI Nakanishi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Roles of cathepsin B in the production of IL-1β as a leptomenigal toxic factor during systemic inflammationPrincipal Investigator
- Principal Investigator
  
  TAKE Hiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Age-dependent differential responses of glial cells and Leptomeningeas during systemic inflammation
- Principal Investigator
  
  SHINDOU Mayumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Okinawa Institute of Science and Technology
Association of leptomeningeal and glial cells in the persistent painPrincipal Investigator
- Principal Investigator
  
  TAKE Hiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Kyushu University
ミクログリアによるグルタミン酸を介した神経伝達の動的制御
- Principal Investigator
  
  NAKANISHI Hiroshi
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University

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All Journal Article Presentation Book

[Book] アリツハイマ―病－発症メカニズムと新規診断法・創薬・治療開発2018
- Author(s)
  武　洲
- Total Pages
  460
- Publisher
  エヌ・ティ－エス株式会社、東京、日本
- ISBN
- Data Source
  KAKENHI-PROJECT-16K11478
[Book] アルツハイマー病－発症メカニズムと新規診断法・創薬・治療開発2018
- Author(s)
  武　洲
- Total Pages
  460
- Publisher
  エヌ・ティ－エス株式会社、東京、日本
- Data Source
  KAKENHI-PROJECT-16H05848
[Book] TNF-α signaling and cathepsin B, In : Tumor Necrosis Factor : Structure, Enzyme Regulation and Role in Health and Disease2013
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Total Pages
  15
- Publisher
  Nova Science Publishers, Inc. New York
- Data Source
  KAKENHI-PROJECT-24390416
[Book] Involvement of microglial cathepsin B in pro-interleukin-1β processing and persistent pain. In : inflammation, Chronic Disease and Cancer-Cell and Molecular Biology, Immunology and Clinic Base2013
- Author(s)
  Hiroshi Nakanishi, Zhou Wu
- Total Pages
  17
- Publisher
  Nova Science Publishers. Inc. New York
- Data Source
  KAKENHI-PROJECT-24390416
[Book] Interleukin-1: Genetics, Inflammatory Mechanisms and Role in Disease2013
- Author(s)
  Hiroshi Nakanishi and Zhou Wu
- Publisher
  Nova Science Publishers, Inc. New York
- Data Source
  KAKENHI-PROJECT-24592802
[Book] BK^+ channels contribute to the cellular activation of microglia : a big channel in small glia, In : Glial Cells : Embryonic Development, Types/Functions and Role in Disease2013
- Author(s)
  Hiroshi Nakanishi, Zhou Wu
- Total Pages
  12
- Publisher
  Nova Science Publishers, Inc., New Yor
- Data Source
  KAKENHI-PROJECT-24390416
[Book] Tumor Necrosis Factor: Structure, Enzyme Regulation and Role in Health and Disease2012
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Publisher
  Nova Science Publishers, Inc. New York
- Data Source
  KAKENHI-PROJECT-24592802
[Journal Article] A mixture of extracts from natural ingredients reduces the neurotoxic polarization of microglia via modulating NF‐κB/NF‐E2-related factor 2 activation2024
- Author(s)
  Gui Shuge、Ni Junjun、Mizutani Shinsuke、Shigematsu Norihiro、Nakanishi Hiroshi、Kashiwazaki Haruhiko、Wu Zhou
- Journal Title
  
  Food Science & Nutrition
  
  Volume: in press Issue: 5 Pages: 3745-3758
- DOI
  10.1002/fsn3.4045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09927
[Journal Article] mtDNA Maintenance and Alterations in the Pathogenesis of Neurodegenerative Diseases2023
- Author(s)
  Zhang Xinwen、Shang Dehao、Huang Minghao、Wang Biyao、Yan Xu、Wu Zhou
- Journal Title
  
  Current Neuropharmacology
  
  Volume: 21 Issue: 3 Pages: 578-598
- DOI
  10.2174/1570159x20666220810114644
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09927
[Journal Article] Zinc finger protein 335 mediates lipopolysaccharide‐induced neurodegeneration and memory loss as a transcriptional factor in microglia2023
- Author(s)
  Kong Wei、Xie Zhen、Shang Xiaokang、Hayashi Yoshinori、Lan Fei、Narengaowa、Zhao Shuxuan、Li Hui、Quan Zhenzhen、Wu Zhou、Nakanishi Hiroshi、Qing Hong、Ni Junjun
- Journal Title
  
  Glia
  
  Volume: 71 Issue: 12 Pages: 2720-2734
- DOI
  10.1002/glia.24447
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09927, KAKENHI-PROJECT-21K06383
[Journal Article] Critical roles of PU.1/cathepsin S activation in regulating inflammatory responses of macrophages in periodontitis2023
- Author(s)
  Zhang Kaige、Wang Sijian、Wang Zihan、Jiang Yiming、Huang Minghao、Liu Nanqi、Wang Biao、Meng Xin、Wu Zhou、Yan Xu、Zhang Xinwen
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 58 Issue: 5 Pages: 939-947
- DOI
  10.1111/jre.13153
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09927
[Journal Article] Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders2022
- Author(s)
  Hook Gregory、Reinheckel Thomas、Ni Junjun、Wu Zhou、Kindy Mark、Peters Christoph、Hook Vivian
- Journal Title
  
  Pharmacological Reviews
  
  Volume: 74 Issue: 3 Pages: 600-629
- DOI
  10.1124/pharmrev.121.000527
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09927
[Journal Article] 歯周病のアルツハイマー病における関与メカニズム2018
- Author(s)
  武　洲、中西　博
- Journal Title
  
  細胞
  
  Volume: 50 Pages: 45-49
- Data Source
  KAKENHI-PROJECT-16K11478
[Journal Article] The critical role of IL-10 in the antineuroinflammatory and antioxidant effects of Rheum tanguticum on activated microglia.2018
- Author(s)
  Meng J, Ni J, Wu Z, Jiang M, Zhu A, Qing H, Nakanishi H.
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2018:1083596 Issue: 1 Pages: 1-12
- DOI
  10.1155/2018/1083596
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11478, KAKENHI-PROJECT-17K17093
[Journal Article] Brazilian green propolis prevents cognitive decline into mild cognitive impairment in elderly people living at high altitude.2018
- Author(s)
  Zhu A, Wu Z, Zhong X, Ni J, Li Y, Meng J, Du C, Zhao X, Nakanishi H, Wu S
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 63 Issue: 2 Pages: 551-560
- DOI
  10.3233/jad-170630
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-17K17093
[Journal Article] Ratanasampil Suppresses the Hypoxia-Related Inflammatory Responses by Inhibiting Oxidative Stress and NF-kB Activation in Microglia2018
- Author(s)
  Zhu Aiqin、Zhong Xin、Nian Wei、Wu Shizheng、Meng Jie、Ni Junjun、Hayashi Yoshinori、Wu Zhou、Nakanishi Hiroshi
- Journal Title
  
  Journal of Alzheimer’s Disease & Parkinsonism
  
  Volume: 08 Issue: 05 Pages: 451-451
- DOI
  10.4172/2161-0460.1000451
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11478
[Journal Article] 歯周病のアルツハイマー病における関与メカニズム2018
- Author(s)
  武　洲、中西　博
- Journal Title
  
  細胞・特集・口腔疾患のサイエンス・Current Topics in Oral Science
  
  Volume: 50 Pages: 45-49
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05848
[Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice2017
- Author(s)
  Liu Yicong、Wu Zhou、Nakanishi Yurika、Ni Junjun、Hayashi Yoshinori、Takayama Fumiko、Zhou Yanmin、Kadawaki Tomoko、Nakanishi Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-12173-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-18K19650
[Journal Article] The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells2017
- Author(s)
  Ni Junjun、Wu Zhou、Meng Jie、Zhu Aiqin、Zhong Xin、Wu Shizheng、Nakanishi Hiroshi
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2017 Issue: 1 Pages: 1-13
- DOI
  10.1155/2017/7984327
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Boi-ogi-to (TJ-20), a Kampo Formula, Suppresses the Inflammatory Bone Destruction and the Expression of Cytokines in the Synovia of Ankle Joints of Adjuvant Arthritic Rats2017
- Author(s)
  Zhang Xinwen、Wu Zhou、Liu Yicong、Ni Junjun、Deng Chunfu、Zhao Baohong、Nakanishi Hiroshi、He Jing、Yan Xu
- Journal Title
  
  Evidence-Based Complementary and Alternative Medicine
  
  Volume: 2017 Issue: 1 Pages: 1-10
- DOI
  10.1155/2017/3679295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017
- Author(s)
  Liu Y, WU Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H
- Journal Title
  
  Sci Rep
  
  Volume: 7:11759
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Journal Article] Dysfunction in diurnal synaptic responses and social behavior abnormalities in cathepsin S-deficient mice2017
- Author(s)
  Takayama Fumiko、Zhang Xinwen、Hayashi Yoshinori、Wu Zhou、Nakanishi Hiroshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 490 Issue: 2 Pages: 447-452
- DOI
  10.1016/j.bbrc.2017.06.061
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Cathepsin B plays a critical role in inducing Alzheimer’s disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice2017
- Author(s)
  Wu Zhou、Ni Junjun、Liu Yicong、Teeling Jessica L.、Takayama Fumiko、Collcutt Alex、Ibbett Paul、Nakanishi Hiroshi
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 65 Pages: 350-361
- DOI
  10.1016/j.bbi.2017.06.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis2017
- Author(s)
  Dekita Masato、Wu Zhou、Ni Junjun、Zhang Xinwen、Liu Yicong、Yan Xu、Nakanishi Hiroshi、Takahashi Ichiro
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 8 Pages: 1-13
- DOI
  10.3389/fphar.2017.00470
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Cathepsin B regulates collagen expression by fibroblasts via prolonging TLR2/NF-kB activation.2016
- Author(s)
  Li X, Wu Z, Ni J, Liu Y, Meng J, Yu W, Nakanishi H, Zhou Y
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2016 Issue: 1 Pages: 7894247-7894247
- DOI
  10.1155/2016/7894247
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11478
[Journal Article] The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells2015
- Author(s)
  Aiqin Zhu, Zhou Wu, Jie Meng, Patrick L. McGeer, Yi Zhu, Hiroshi Nakanishi, and Shizheng Wu
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2015 Pages: 1-10
- DOI
  10.1155/2015/792342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood-brain barrier2015
- Author(s)
  Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 64 Pages: 51-60
- DOI
  10.1016/j.mcn.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-26861555, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage2015
- Author(s)
  XJunjun Ni, Zhou Wu, Christoph Peterts, Kenji Yamamoto, Hong Qing, and Hiroshi Nakanishi2015
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 35 Issue: 36 Pages: 12488-12501
- DOI
  10.1523/jneurosci.1599-15.2015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] Downward spiral of periodontitis and diabetes into Alzheimer's disease: Extending healthy life expectancy through oral health. J2015
- Author(s)
  Hiroshi Nakanishi, Zhou Wu
- Journal Title
  
  J Oral Biosci
  
  Volume: 57 Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05015
[Journal Article] Lessons from Microglia Aging for the Link between Inflammatory Bone Disorders and Alzheimer’s Disease2015
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Journal Title
  
  Journal of Immunology Research
  
  Volume: 2015 Pages: 471342-471342
- DOI
  10.1155/2015/471342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state.2014
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: 34 Pages: 3013-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592802
[Journal Article] Connection Between Periodontitis and Alzheimer’s Disease: Possible Roles of Microglia and Leptomeningeal Cells2014
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 126 Issue: 1 Pages: 8-13
- DOI
  10.1254/jphs.14R11CP
- NAID
  130004684880
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390416
[Journal Article] Autophagy in superficial spinal dorsal horn accelerates the cathepsin B-dependent morphine antinociceptive tolerance2014
- Author(s)
  Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
- Journal Title
  
  Neuroscience
  
  Volume: 275 Pages: 384-394
- DOI
  10.1016/j.neuroscience.2014.06.037
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24791979
[Journal Article] Leptomeningeal cells transduce peripheral macrophages inflammatory signal to microglia in response to Porphyromonas gingivalis LPS2013
- Author(s)
  Yicong Liu, Zhou Wu, Xinwen Zhang, Junjun Ni, Weixian Yu, Yanmin Zhou, Hiroshi Nakanishi
- Journal Title
  
  Mediators Inflamm
  
  Volume: 2013:407562 Pages: 1-11
- DOI
  10.1155/2013/407562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013
- Author(s)
  Fumiko Takayama, Zhou Wu, Hong Ma HM, Okada R, Yoshinori Hayashi, Hiroshi Nakanishi
- Journal Title
  
  J Neuroimmunol
  
  Volume: 262 Issue: 1-2 Pages: 121-124
- DOI
  10.1016/j.jneuroim.2013.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
[Journal Article] Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-kB activation in microglia2013
- Author(s)
  Zhou Wu, Aiqin Zhu, Fumiko Takayama, Ryo Okada, Yicong Liu, Yuka Harada, Shizheng Wu, Hiroshi Nakanishi
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2013:906726 Pages: 1-10
- DOI
  10.1155/2013/906726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state2013
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: 34 Pages: 3013-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416
[Journal Article] Differential pathways for interleukin-1b production activated by chromogranin A and amyloid β in microglia2013
- Author(s)
  Zhou Wu, Li Sun, Sadayuki Hashioka, Yu S, Schwab C, Ryo Okada, Yoshinori Hayashi, Patrick L McGeer PL, Hiroshi Nakanishi
- Journal Title
  
  Neurobiol Aging
  
  Volume: 34 Issue: 12 Pages: 2715-2725
- DOI
  10.1016/j.neurobiolaging.2013.05.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
[Journal Article] Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation2012
- Author(s)
  Liu X, Wu Z, Hayashi Y, Nakanishi H
- Journal Title
  
  Neuroscience
  
  Volume: 216 Pages: 133-142
- DOI
  10.1016/j.neuroscience.2012.04.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-induced Chronic Pain.2012
- Author(s)
  S. Li, Z. Wu, Y. Hayashi, C. Peters, K. Inoue, M. Tsuda, and H. Nakanishi.
- Journal Title
  
  J.Neurosci.
  
  Volume: 32(33) Issue: 33 Pages: 11330-42
- DOI
  10.1523/jneurosci.0677-12.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Presentation] 歯周病のアルツハイマー型認知症への関与メカニズム2024
- Author(s)
  武　洲
- Organizer
  長崎長崎県保険医協会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] 口腔から考える認知症予防2023
- Author(s)
  武　洲
- Organizer
  第23回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] P.ジンジバリス菌は脳血管内皮細胞を介したAmyloid beta 脳内流入を促進する2023
- Author(s)
  武　洲、桂淑格,　水谷慎介、柏崎晴彦
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] P.gingivalis菌感染は髄膜細胞に誘導されるIL-1 beta を介してシナプス障害を引き起こす2023
- Author(s)
  武　洲、桂　淑格、水谷慎介、柏崎　晴彦
- Organizer
  第53回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] 口腔から認知症予防策を考える2023
- Author(s)
  武　洲
- Organizer
  全国保険医団体連合会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] Pathogenesis and intervention of dementia2023
- Author(s)
  武　洲
- Organizer
  中国紹興文理学院講演会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] 口腔感染症と認知症：関連メカニズムから予防策を考える2022
- Author(s)
  武　洲
- Organizer
  第30回日本病態生理学会大会・記念シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] 認知症を口から防ぐ　ー口腔ブレインサイエンスー2022
- Author(s)
  武　洲
- Organizer
  国際医科学研究会第20回フォーラム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] 「歯周病菌のアルツハイマー型認知症への関与メカニズム」2022
- Author(s)
  武　洲
- Organizer
  第11回日本認知症予防学会・学術集会　教育講演
- Invited
- Data Source
  KAKENHI-PROJECT-22K09927
[Presentation] Porphyromonas gingivalis由来LPSの慢性投与は中年モウスにおける骨量低下ならびに記憶低下を誘発する2018
- Author(s)
  Yebo Gu, Junjun Ni, Zhou Wu, Ichiro Takahashi
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] 慢性全身性Porphyromonas gingivalis感染に伴う全身性アミロイドβ代謝におけるマクロファージの関与2018
- Author(s)
  5.Ran Nie, Junjun Ni, Yoshinori Hayashi, Zhou Wu, Yanmin Zhou
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] チベット薬Ratanasampilは、低酸素によるミクログリアにおける酸化ストレスならびにNF-κB活性化に依存した炎症反応を抑制する2018
- Author(s)
  Jie Meng, Junjun Ni, Yoshinori Hayashi, Hiroshi Nakanishi, Aiqin Zhu　and Zhou Wu
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Porphyromonas gingivalis由来LPSの慢性投与は中年モウスにおける骨量低下ならびに記憶低下を誘発する2018
- Author(s)
  Yebo Gu, Junjun Ni, Zhou Wu, Ichiro Takahashi
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] ジンジバリス菌とアルツハイマー病2018
- Author(s)
  武　洲
- Organizer
  2018年「Hindgut Club Japan」シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] ジンジバリス菌とアルツハイマー病2018
- Author(s)
  武　洲
- Organizer
  第60回歯科基礎医学会学術大会・メインシンポジウム
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] ジンジバリス菌とアルツハイマー病2018
- Author(s)
  武　洲
- Organizer
  第60回歯科基礎医学会学術大会・メインシンポジウム, オーガナイザー・講演
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 慢性全身性Porphyromonas gingivalis感染に伴う全身性アミロイドβ代謝におけるマクロファージの関与2018
- Author(s)
  Ran Nie, Junjun Ni, Yoshinori Hayashi, Zhou Wu, Yanmin Zhou
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] 8The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-22017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病と認知機能：増悪機序の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90回日本薬理学会年会（年会企画シンポジウム：口腔ブレインサイエンスに学ぶ健康長寿）
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017
- Author(s)
  Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi,
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] L-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017
- Author(s)
  Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] ミクログリアによる脳炎症を主軸とする歯周病のアルツハイマー病増悪メカニズムの解明2017
- Author(s)
  武　洲
- Organizer
  第90回日本薬理学会年会・年会企画シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病菌によるアルツハイマー様脳病態の発症と原因酵素としてのカテプシン群の役割2017
- Author(s)
  武洲、中西博
- Organizer
  第59回歯科基礎医学会学術大会学術シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Microglia-mediated neuroinflammation in cognitive decline: Evidence, Mechemism and Prevention by natural production2017
- Author(s)
  Zhou Wu
- Organizer
  NEUROTALK-2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病菌によるアルツハイマー様脳病態の発症と原因酵素としてのカテプシン群の役割2017
- Author(s)
  武　洲
- Organizer
  第58回歯科基礎医学会学術大会・学術シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Increased expression and altered subcellular distribution of Cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging2017
- Author(s)
  Junjun Ni, Zhou Wu and Hiroshi Nakanishi
- Organizer
  The 22nd Annual Meeting of Japan Glia
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Microglia-mediated neuroinflammation in cognitive decline: Evidence, Mechemism and Prevention by natural production.2017
- Author(s)
  Zhou Wu
- Organizer
  NEUROTALK-2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] 歯周病と認知症:増悪機構の解明と今後の展望2017
- Author(s)
  武洲、中西博
- Organizer
  第90本薬理学会年会年会企画シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] 歯周病と認知機能：増悪機序の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90回日本薬理学会年会（年会企画シンポジウム：口腔ブレインサイエンスに学ぶ健康長寿）
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病と認知機能：増悪機序の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90回日本薬理学会年会（年会企画シンポジウム：口腔ブレインサイエンスに学ぶ健康長寿）
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Hiroshi Nakanishi
- Organizer
  95tth Annual Meeting of International Association for Dental Research (IADR2017)
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Critical roles of cathepsin B in Alzheimer’s disease-like phenotypes following chronic systemic exposure to Porphyromonas gingivalis2017
- Author(s)
  Zhou Wu Junjun Ni, Yicong Liu and Hiroshi Nakanishi
- Organizer
  ISN-ESN Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)、2017
- Author(s)
  Yicong Liu, Zhou Wu, Hiroshi Nakanishi,
- Organizer
  95tth Annual Meeting of International Association for Dental Research (IADR2017)
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Gingipain Induce Microglia Migration through activation of protease-activated receptor-22017
- Author(s)
  Yicong Liu , Zhou Wu and Hiroshi Nakanishi
- Organizer
  95th Annuak Meeting of International Association for Dental Research (IADR 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia、2017
- Author(s)
  Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病菌によるアルツハイマー様脳病態の発症と原因酵素としてのカテプシン群の役割2017
- Author(s)
  武　洲
- Organizer
  第58回歯科基礎医学会学術大会・学術シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Critical roles of cathepsin B in Alzheimer’s disease-like phenotypes following chronic systemic exposure to Porphyromonas gingivalis.2017
- Author(s)
  Zhou Wu Junjun Ni, Yicong Liu and Hiroshi Nakanishi
- Organizer
  ISN-ESN Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017
- Author(s)
  Yicong Liu, Zhou Wu and Hiroshi Nakanishi
- Organizer
  the 22nd Annual Meeting of Japan Glia
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Hiroshi Nakanishi
- Organizer
  95tth Annual Meeting of International Association for Dental Research (IADR2017)
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017
- Author(s)
  Yicong Liu, Zhou Wu and Hiroshi Nakanishi
- Organizer
  The 22nd Annual Meeting of Japan Glia
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] ミクログリアによる脳炎症を主軸とする歯周病のアルツハイマー病増悪メカニズムの解明2017
- Author(s)
  武　洲
- Organizer
  第90回日本薬理学会年会・年会企画シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Increased expression and altered subcellular distribution of Cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging2017
- Author(s)
  Junjun Ni, Zhou Wu and Hiroshi Nakanishi
- Organizer
  the 22nd Annual Meeting of Japan Glia
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Gingipain Induce Microglia Migration through activation of protease-activated receptor-2. 95th Annuak Meeting of International Association for Dental Research2017
- Author(s)
  Yicong Liu , Zhou Wu and Hiroshi Nakanishi
- Organizer
  IADR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2（PAR-2）の活性化を介したミクログリアの細胞遊走誘導2016
- Author(s)
  劉　訳聡、武　洲、朱　愛琴、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2（PAR-2）の活性化を介したミクログリアの細胞遊走誘導2016
- Author(s)
  劉　訳聡、武　洲、門脇知子、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2（PAR-2）の活性化を介したミクログリアの細胞遊走誘導2016
- Author(s)
  劉　訳聡、武　洲、門脇知子、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses2016
- Author(s)
  Junjun Ni, Zhou Wu, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses2016
- Author(s)
  Junjun Ni, Zhou Wu, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016
- Author(s)
  孟ジェイ、武　洲、朱　愛琴、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016
- Author(s)
  孟ジェイ、武　洲、朱　愛琴、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016
- Author(s)
  武　洲、中西　博
- Organizer
  第58回歯科基礎医学会学術大会（サテライトシンポジウム：健康長寿社会を目指す口腔ブレインサイエンスの最前線）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016
- Author(s)
  孟ジェイ、武　洲、門脇知子、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016
- Author(s)
  武　洲、中西　博
- Organizer
  第58回歯科基礎医学会学術大会（サテライトシンポジウム：健康長寿社会を目指す口腔ブレインサイエンスの最前線）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016
- Author(s)
  武　洲、中西　博
- Organizer
  第58回歯科基礎医学会学術大会（サテライトシンポジウム：健康長寿社会を目指す口腔ブレインサイエンスの最前線）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Cathepsin B, a novel therapeutic target for microglia-aging2016
- Author(s)
  Zhou Wu
- Organizer
  XVth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  ポートローズ、スロベニア
- Year and Date
  2016-09-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Cathepsin B, a novel therapeutic target for microglia-aging2016
- Author(s)
  Zhou Wu
- Organizer
  XVth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  ポートローズ、スロベニア
- Year and Date
  2016-09-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses,2016
- Author(s)
  Junjun Ni, Zhou Wu, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016
- Author(s)
  Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] ossible involvement of cathepsin H in the negative regulatio2016
- Author(s)
  Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi,
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K11478
[Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016
- Author(s)
  Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Critical roles of cathepsin B in AD-like phenotypes in middle-aged mice following chronic systemic treatment with lipopolyssacharide from Porphyromonas gingivalis2015
- Author(s)
  Junjun Ni、Zhou Wu、 Hiroshi Nakanishi
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟（新潟）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Involvement of brain pericyte damage in neuropathological changes associated eith lysosomal storage2015
- Author(s)
  Zhou Wu, Ryo Okada、Hiroshi Nakanishi
- Organizer
  The 4th International Conference and Exhibition on Neurology & Therapeutics
- Place of Presentation
  Holiday Inn Rome Aurelia（ローマ）
- Year and Date
  2015-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] ATPならびにPorphyromonas gingivalis（PG）局所注入により惹起されるミクログリア突起の集積とその日内変化に関する生体イメージング解析2015
- Author(s)
  髙山扶美子、林良憲、武洲、中西博
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟（新潟）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] カテプシンSは告げんの日無い変化がもたらすミクログリアならびにニューロン機能の日内変化2014
- Author(s)
  高山扶美子、林　良憲、武　洲、中西　博
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学ラマツィーニホール（福岡）
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] プロポリスのカテプシンS 発現制御を介したTh1 応答抑制作用2014
- Author(s)
  張馨文、武洲、中西博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Cathepsin B is a possible phenotype switch along the M1-M2 phenotypic continuum of microglia/macrophages2014
- Author(s)
  倪　軍軍、武　洲、中西　博
- Organizer
  第19回グリア研究会
- Place of Presentation
  東京商工会議所（東京）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Involvement of cathepsin S in the diurnal morphological and functional changes of cortical microglial processes2014
- Author(s)
  高山扶美子、林良憲、武洲、中西博
- Organizer
  第21回日本時間生物学会学術大会
- Place of Presentation
  九州大学医学部百年講堂（福岡）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Cathepsin B is positive phenotype switch the M1-M2 phenotypic continuum of microglia/macrophages2014
- Author(s)
  JunJun Ni、武　洲、中西　博
- Organizer
  第19回グリア研究会
- Place of Presentation
  東京
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] クログリアの2種類の突起の日内変化に関する形態学的ならびに生体イメージング解析2014
- Author(s)
  髙山扶美子、林良憲、武洲、中西博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] クロモグラニンAはβアミロイドよりも強力にミクログリアにおけるIL-1β産生を誘導する2012
- Author(s)
  武　洲, 中西　博
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] クロモグラニンAの慢性炎症性疼痛における役割の解析2012
- Author(s)
  孫麗, 武　洲, 林　良憲, 中西　博
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] Slow Brain-Aging from Regulation of Systemic Inflammation and Microglia2012
- Author(s)
  Wu Zhou
- Organizer
  Institute of Geriatric Qinghai Provincial Hospital
- Place of Presentation
  Xining, Qinghai, China
- Invited
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 神経障害性疼痛におけるミクログリアのカテプシンSの関与2010
- Author(s)
  張馨文、孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 中年ルイスラットにおけるアジュバント関節炎に伴うミクログリア活性化と海馬長期増強の障害2010
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第63回日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアの産生するカテプシンS の神経障害性疼痛発症における役割2010
- Author(s)
  張馨文、林良憲、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 神経障害性疼痛におけるミクログリアのカテプシンSの関与2010
- Author(s)
  張馨文、孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 炎症性疼痛発症におけるミクログリアのカテプシンBの関与2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアの産生するカテプシンBの炎症性疼痛発症における役割2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ホスファチジルセリンリポソームによる炎症性骨破壊抑制メカニズムの解析2010
- Author(s)
  武洲、馬紅梅、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ホスファチジルセリンリポソームによる骨形成の促進2010
- Author(s)
  馬紅梅、武洲、李銀姫、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010
- Author(s)
  武洲, 劉霞, 中西博
- Organizer
  The 1^<st> International Congress on Controversies in Longevity, Health and Aging.
- Place of Presentation
  バルセロナ
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Microglial cathepsin B :A strategic target for neuroprotective agents.2010
- Author(s)
  武洲, 中西博
- Organizer
  BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010.
- Place of Presentation
  上海
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 慢性末梢炎症によるミクログリア活性化と海馬LTPの障害2010
- Author(s)
  劉霞、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 炎症性疼痛発症におけるミクログリアのカテプシンBの関与2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ホスファチジルセリンリポソームによる骨形成の促進2010
- Author(s)
  馬紅梅、武洲、李銀姫、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアの産生するカテプシンBの炎症性疼痛発症における役割2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 慢性末梢炎症によるミクログリア活性化と海馬LTP障害2010
- Author(s)
  劉霞、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 中年ルイスラットにおけるアジュバント関節炎に伴うミクログリア活性化と海馬長期増強の障害2010
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第63回日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ミクログリアの産生するカテプシンS の神経障害性疼痛発症における役割2010
- Author(s)
  張馨文、林良憲、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Microglial cathepsin B : A strategic target for neuroprotective agents.2010
- Author(s)
  武洲, 中西博
- Organizer
  BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010.
- Place of Presentation
  上海
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] A possible involvement of cathepsin B in nociceptive processing through the processing and secretion of interleukin-1 family from microglia.2010
- Author(s)
  孫麗, 武洲, 林良憲, 中西博
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンジエゴ
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010
- Author(s)
  武洲, 劉霞, 中西博
- Organizer
  The 1^<st> International Congress on Controversies in Longevity, Health and Aging.
- Place of Presentation
  バルセロナ
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ホスファチジルセリンリポソームによる炎症性骨破壊抑制メカニズムの解析2010
- Author(s)
  武洲、馬紅梅、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] インターロイキン-1βのp38MAPキナーゼの活性化を介したNMDAにより惹起されるCa^<2+>活性化K^+電流の抑制作用2009
- Author(s)
  Zhang R, 劉霞、孫麗、林良憲、武洲、中西博
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Age-dependent differential phenotypic changes of glial cells by systemic inflammation.2009
- Author(s)
  武洲, 中西博
- Organizer
  9^<th> European Meeting on Glial Cells in Health and Disease.
- Place of Presentation
  パリ
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 末梢炎症によるミクログリア活性化と脳老化の促進2009
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第14回グリア研究会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 末梢炎症によるミクログリア活性化と脳老化の促進2009
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第14回グリア研究会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] インターロイキン-1βのp38MAPキナーゼの活性化を介したNMDAにより惹起されるCa^<2+>活性化K^+電流の抑制作用2009
- Author(s)
  Zhang R,劉霞、孫麗、林良憲、武洲、中西博
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differential phenotypic changes of glial cells by systemic inflammation.2009
- Author(s)
  武洲, 中西博
- Organizer
  9^<th> European Meeting on Glial Cells in Health and Disease.
- Place of Presentation
  パリ
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differential microglial and astrocytic responses through leptomeninges during systemic inflammation.2009
- Author(s)
  武洲, 徳田幸恵, 張馨文, 中西博
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 破骨前駆細胞の貪食機能に着目した新たな骨破壊抑制法2008
- Author(s)
  武洲、馬紅梅、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミトコンドリア転写因子Aの過剰発現によるミトコンドリア内レドックス制御ならびに老化に伴う脳機能低下の制御2008
- Author(s)
  中西博、林良憲、井手友美、武洲
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミトコンドリア転写因子Aの過剰発現によるミトコンドリア内レドックス制御ならびに老化に伴う脳機能低下の制御2008
- Author(s)
  中西博、林良憲、井手友美、武洲
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Phospathidylserine-containing liposomes ameliorates the cytokine imbalance in the ankle joints of adjuvant arthritic rats.2008
- Author(s)
  馬紅梅、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differentiation of the barrier function of the leptomeninges in the cerebral cortex by activated glial cells during the systemic inflammation.2008
- Author(s)
  武洲, 徳田幸恵, 張馨文, 中西博
- Organizer
  第26回CINP
- Place of Presentation
  ミュンヘン
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 末梢炎症に対する髄膜-グリア連関の汎脳性の老化に伴う変容2008
- Author(s)
  武洲、中西博
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 末梢炎症に対する髄膜-グリア連関の反応の老化に伴う変容2008
- Author(s)
  武洲, 中西博
- Organizer
  第61回日本西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Age-dependent differentiatial regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008
- Author(s)
  武洲, 中西博
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 末梢炎症に対する髄膜.グリア連関の反応の老化に伴う変容2008
- Author(s)
  武洲
- Organizer
  第61回日本西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Age-dependent differentiatial regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008
- Author(s)
  武洲, 中西博
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 末梢炎症に対する髄膜-グリア連関の汎脳性の老化に伴う変容2008
- Author(s)
  武洲、中西博
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 破骨細胞の貪食機能に着目した新たな骨破壊抑制法2008
- Author(s)
  武洲, 他
- Organizer
  第50回歯科基礎医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] 中高年における慢性末梢炎症は深刻な脳炎症を引き起こす2008
- Author(s)
  徳田幸恵、張馨文、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Phospathidylserine-containing liposomes ameliorates the cytokine imbalance in the ankle joints of adjuvant arthritic rats.2008
- Author(s)
  馬紅梅、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 中高年における慢性末梢炎症は深刻な脳炎症を引き起こす2008
- Author(s)
  徳田幸恵、張馨文、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons.2008
- Author(s)
  張馨文, 武洲, 中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 破骨前駆細胞の貪食機能に着目した新たな骨破壊抑制法2008
- Author(s)
  武洲、馬紅梅、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ミクログリアのカテプシンS発現リズムによるシナプス強度の調節機構の解明
- Author(s)
  林　良憲、小柳悟、楠瀬直樹、岡田　亮、武　洲、斉藤秀俊、大戸茂弘、高坂新一、井上和秀、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 歯周病菌による脳髄膜を介したミクログリアの活性化
- Author(s)
  武　洲、中西　博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] 歯周病菌による脳髄膜を介したミクログリアの活性化
- Author(s)
  武　洲、中西　博
- Organizer
  第56回歯科基礎医学会学術大会サテライトシンポジウム
- Place of Presentation
  福岡国際センター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] Batten病モデルマウスにおける脳ペリサイトの酸化ストレス障害と血液脳関門の破綻
- Author(s)
  岡田　亮、武　洲、倪　軍軍、中西　博
- Organizer
  第18回グリア研究会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] クロモグラニンA（CGA）によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明
- Author(s)
  武　洲、中西　博
- Organizer
  第55回歯科基礎医学学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] 神経障害性トプ痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 歯周病菌によるアルツハイマー様脳病態の促進メカニズム
- Author(s)
  武　洲
- Organizer
  第88回日本薬理学会年会シンポジウム
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] クロモグラニンA（CGA）によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明
- Author(s)
  武　洲、中西　博
- Organizer
  第55回歯科基礎医学学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Batten病モデルマウスにおける脳ペリサイトの酸化ストレス障害と血液脳関門の破綻
- Author(s)
  岡田　亮、武　洲、倪　軍軍、中西　博
- Organizer
  第18回グリア研究会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] 2種類のミクログリア突起の日内変化に関する形態学的ならびに生体イメージング解析
- Author(s)
  高山　扶美子　林　良憲、武　洲、中西　博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際センター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 歯周病菌によるアルツハイマー様脳病態の促進メカニズム
- Author(s)
  武　洲、中西　博
- Organizer
  第88回日本薬理学学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] The possible link between periodontitis and Alzheimer's disease
- Author(s)
  武　洲、中西　博
- Organizer
  中国薬理学会・老年医学会・認知機能障害と関連疾患シンポジウム
- Place of Presentation
  中国　青海省西寧市
- Year and Date
  2014-08-09 – 2014-08-11
- Invited
- Data Source
  KAKENHI-PROJECT-24592802

1. NAKANISHI Hiroshi (20155774)

# of Collaborated Projects: 9 results

# of Collaborated Products: 116 results
2. SHINDOU Mayumi (10444796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HAYASHI Yoshinori (80582717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. 田中嘉孝 (20217095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 門司晃 (00294942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 西村英紀 (80208222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 倪軍軍

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 井上和秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

zhou wu 武 洲

武 洲 タケ ヒロ

TAKE Hiro 武 洲

Research Projects

Research Products

Co-Researchers

ジンジバリス菌の神経血管ユニット破綻を招く機構Principal Investigator

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Elucidating new mechanism of brain barrier-synaptic disruptions caused by P. gingivitisPrincipal Investigator

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Japan-China Joint Epidemiological Survey of Tibetan Elderly on Correlation between Oral Health and Cognitive FunctionsPrincipal Investigator

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Elucidation of Alzheimer's disease exacerbation mechanism of periodontitis centering on microglia-related neuroinflammationPrincipal Investigator

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Study on a microglial phenotypic switch with a focus on proteolytic response

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Critical roles of the chromogranin A-cathepsin B system in a transition of acute pain to a chronic pain state

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Mechanism of the rupture of meningeal-glia limitans during chronic PeriodontitisPrincipal Investigator

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Inhibition of bone destruction by phosphatidylserine-containing liposomes based on t he regulation of phagocytes functions

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Roles of cathepsin B in the production of IL-1β as a leptomenigal toxic factor during systemic inflammationPrincipal Investigator

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Age-dependent differential responses of glial cells and Leptomeningeas during systemic inflammation

Principal Investigator

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Association of leptomeningeal and glial cells in the persistent painPrincipal Investigator

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ミクログリアによるグルタミン酸を介した神経伝達の動的制御

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[Book] アリツハイマ―病－発症メカニズムと新規診断法・創薬・治療開発2018

Author(s)

zhou wu 武洲

武洲タケヒロ

TAKE Hiro 武洲