Asai Daisuke 浅井大輔

… Alternative Names

ASAI Daisuke 浅井大輔

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Researcher Number	10423485
Other IDs	https://orcid.org/0000-0003-4015-6694
External Links
Affiliation (Current)	2024: 昭和薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 昭和薬科大学, 薬学部, 准教授 2020 – 2022: 昭和薬科大学, 薬学部, 准教授 2017 – 2019: 聖マリアンナ医科大学, 医学部, 講師 2012 – 2016: 聖マリアンナ医科大学, 医学部, 助教 2014: 聖マリアンナ医科大学, 微生物学教室, 助教 2007 – 2009: St.Marianna University School of Medicine, 医学部, 助教 2006: 聖マリアンナ医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 90120:Biomaterials-related / Medical pharmacy Except Principal Investigator Basic Section 35020:Polymer materials-related / Medium-sized Section 37:Biomolecular chemistry and related fields / Infectious disease medicine / Biomedical engineering/Biomaterial science and engineering / Analytical chemistry
Keywords	Principal Investigator エラスチン / DDS / 注射ゲル / 徐放 / ドラッグデリバリー / 抗菌ペプチド / バイオテクノロジー / 感染症 / 人工エラスチン / アジュバント … More / ワクチン / 生体材料 / インジェクタブルポリマー / 薬物デポ / ポリペプチド / 生分解材料 / ハイドロゲル / 遺伝子治療 / 遺伝子キャリアー / NF-kappaB / IkappaB kinase / 徐放製剤 / 抗微生物薬 / 創剤 / デポ製剤 / 薬剤耐性菌 / 生分解性ポリマー / 生体生命情報学 / 免疫学 / 破傷風 / 破傷風トキソイド / バルクゲル / 抗原徐放 / ワクチン抗原 / バイオレオロジー / ペプチド送達 / ペプチド医薬 / 生体吸収性高分子 / 遺伝子工学 / バイオマテリアル / ドラッグデリバリーシステム / 温度応答性高分子 / ペプチド / IkappaBkinase / 遺伝子デリバリー … More Except Principal Investigator がん / 抗ウイルス性 / 硫酸化オリゴ糖鎖 / SPR / 相互作用 / リポソーム / クリック反応 / オリゴ糖鎖 / 長鎖アルキル鎖 / 動的光散乱（DLS）装置 / 表面プラズモン共鳴（SPR）装置 / オリゴペプチド / ウイルス表皮タンパク質 / 硫酸化アルキルオリゴ糖鎖 / 硫酸化糖鎖 / 膜抗原 / 免疫組織化学 / がん診断 / 分子プローブ / 酵素基質 / コンパニオン診断 / 蛍光分子プローブ / フローサイトメトリー / 細胞膜抗原 / 質量分析 / MRSA / 薬剤耐性機構 / プロテオミクス / 薬剤耐性 / 黄色ブドウ球菌 / デポ製剤 / 生分解材料 / 注射ゲル / 生体材料 / エラスチン / 徐放 / DDS / ペプチド製剤 / 創剤 / 注射ゲル製剤 / 人工エラスチン / 高分子型プロドラッグ / ポリペプチド / 薬物送達 / 抗HIVペプチド / 抗HIV / 創薬 / ペプチドアレイ / バイオチップ / キノーム / 診断 / 薬物探索 / 蛍光分析 / ペプチド / マイクロアレイ / プロテインキナーゼ Less

Development of a depot formulation that senses the bacterial infection environment and releases antimicrobial peptide drugsPrincipal Investigator
- Principal Investigator
  
  浅井大輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Showa Pharmaceutical University
Elucidation of unresolved anti-HIV mechanism of sulfated polysaccharides
- Principal Investigator
  
  Yoshida Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 35020:Polymer materials-related
- Research Institution
  Kitami Institute of Technology
Development of antimicrobial agents: challenges by artificial multifunctional biopolymersPrincipal Investigator
- Principal Investigator
  
  Asai Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Showa Pharmaceutical University
Ultra-sensitive detection method of membrane antigens and its application to cancer companion diagnosis
- Principal Investigator
  
  Katayama Yoshiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyushu University
Development of molecular bases of next generation vaccine: Approach from antigen depot delivery systemPrincipal Investigator
- Principal Investigator
  
  Asai Daisuke
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Showa Pharmaceutical University
  St. Marianna University School of Medicine
Development of anti HIV peptide applying multifunctional polypeptide
- Principal Investigator
  
  Nakashima Hideki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  St. Marianna University School of Medicine
Proteomic analysis for drug-resistant mechanisms of Staphylococcus aureus
- Principal Investigator
  
  KANAMOTO Taisei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Showa Pharmaceutical University
  St. Marianna University School of Medicine
Development of novel depot-forming bioabsorbable recombinant elastomers for immunoresponse augmentationPrincipal Investigator
- Principal Investigator
  
  Asai Daisuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  St. Marianna University School of Medicine
Peptide microarray for prognosis of cancer chemotherapy
- Principal Investigator
  
  KATAYAMA Yoshiki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Analytical chemistry
- Research Institution
  Kyushu University
Development of novel platform for injectable in vivo drug delivery systemPrincipal Investigator
- Principal Investigator
  
  ASAI Daisuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  St. Marianna University School of Medicine
Development of inflammatory cell-specific gene regulation system for gene therapeutic strategyPrincipal Investigator
- Principal Investigator
  
  ASAI Daisuke
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  St.Marianna University School of Medicine
炎症細胞特異的な遺伝子送達を目指した遺伝子キャリアーの創製Principal Investigator
- Principal Investigator
  
  浅井大輔
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  St.Marianna University School of Medicine

[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術, 第7章　ペプチド医薬品の製剤化技術　第２節　抗HIVペプチドのデポ製剤化2017
- Author(s)
  浅井大輔, 中島秀喜
- Total Pages
  587
- Publisher
  (株)技術情報協会
- ISBN
- Data Source
  KAKENHI-PROJECT-17K08254
[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術, 第7章　ペプチド医薬品の製剤化技術　第２節　抗HIVペプチドのデポ製剤化2017
- Author(s)
  浅井大輔, 中島秀喜
- Total Pages
  587
- Publisher
  (株)技術情報協会
- ISBN
- Data Source
  KAKENHI-PROJECT-15K01319
[Book] 国際科学技術財團研究助成研究内容解説(疾患細胞選択的な遺伝子発現制御技術の創出と治療への応用(細胞と対話する技術の創出-薬物を病変細胞でだけ働かせる新しい考え方))2009
- Author(s)
  浅井大輔
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Synthesis and cytotoxic mechanism of sulfated alkyl oligosaccharides having potent anti-HIV activity2023
- Author(s)
  B. Mingxue, D. Asai, T. Koshikawa, H. Takemura, K. Miyazaki, and T. Yoshida
- Journal Title
  
  J. Fiber Sci. Technol.
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Synthesis and cytotoxic mechanism of sulfated alkyl oligosaccharides having potent anti-HIV activity2023
- Author(s)
  Bai, Asai, Koshikawa, Takemura, Miyazaki, Yoshida
- Journal Title
  
  J. Fiber Sci. Technol.
  
  Volume: 79 Pages: 101-111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05612
[Journal Article] Electrostatic interaction between sulfated polysaccharides and oligopeptides from viral envelope glycoproteins using surface plasmon resonance2023
- Author(s)
  T. Battulga, A. Dagaerbieke, C. Bai, D. Asai, T. Koshikawa, H. Takemura, K. Miyazaki, and T. Yoshida
- Journal Title
  
  Carbohydr. Res.
  
  Volume: 528 Pages: 108815-108815
- DOI
  10.1016/j.carres.2023.108815
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Evaluation of electrostatic interaction between sulfated polysaccharides and oligopeptides from viral envelope glycoproteins using surface plasmon resonance2023
- Author(s)
  Tungalag, Ayiguli, Chaolumen, Asai, Koshikawa, Takemura, Miyazaki, Yoshida
- Journal Title
  
  Carbohydr. Res.
  
  Volume: 530 Pages: 108815-108815
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05612
[Journal Article] A model of transcriptional activation of DNA by loosening of chromatin structure2022
- Author(s)
  Y.T. Sato, D. Asai, K. Terada, J.H. Kang, T. Mori, T. Niidome, H. Nakashima, and Y. Katayama
- Journal Title
  
  Chem. Lett.
  
  Volume: 51 Issue: 12 Pages: 1109-1112
- DOI
  10.1246/cl.220392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Importance of accessibility to the extracellular juxtamembrane stalk region of membrane protein for substrate recognition by viral ubiquitin ligase K52022
- Author(s)
  Kajikawa Mizuho、Hata Mizuki、Ishimura Maho、Imaizumi Nanae、Kimura Minako、Miyano Kei、Ose Toyoyuki、Asai Daisuke、Ishido Satoshi、Kanamoto Taisei
- Journal Title
  
  Biochemical Journal
  
  Volume: 479 Issue: 20 Pages: 2261-2278
- DOI
  10.1042/bcj20220288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06934, KAKENHI-PROJECT-20K12657
[Journal Article] Old but still useful [γ-32P]ATP ―Development of peptide substrates for protein kinases by 32P-based enzyme activity assay―2022
- Author(s)
  D. Asai, J.H. Kang, and Y. Katayama
- Journal Title
  
  BUNSEKI KAGAKU
  
  Volume: 71 Pages: 179-185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Evaluation of a new point-of-care quantitative reverse transcription polymerase chain test for detecting severe acute respiratory syndrome coronavirus 22021
- Author(s)
  Y. Watanabe, R. Oikawa, T. Suzuki, H. Funabashi, D. Asai, Y. Hatori, H. Takemura, H. Yamamoto, and F. Itoh
- Journal Title
  
  J. Clin. Lab. Anal.
  
  Volume: 35 Issue: 10
- DOI
  10.1002/jcla.23992
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Direct evidence of edge-to-face CH/π interaction for PAR-1 thrombin receptor activation2021
- Author(s)
  Asai Daisuke、Inoue Naoko、Sugiyama Makiko、Fujita Tsugumi、Matsuyama Yutaka、Liu Xiaohui、Matsushima Ayami、Nose Takeru、Costa Tommaso、Shimohigashi Yasuyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 51 Pages: 116498-116498
- DOI
  10.1016/j.bmc.2021.116498
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12340, KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-20H00635
[Journal Article] Lignosulfonate rapidly inactivates human immunodeficiency and herpes simplex viruses2021
- Author(s)
  K. Fukuchi, T. Koshikawa, D. Asai, M. Inomata, H. Sakagami, H. Takemura, T. Kanamoto, H. Aimi, and Y. Kikkawa
- Journal Title
  
  Medicines (Basel)
  
  Volume: 8 Issue: 10 Pages: 1-17
- DOI
  10.3390/medicines8100056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-21K09849
[Journal Article] Re-evaluation of chemotherapeutic potential of pyoktanin blue2021
- Author(s)
  H. Sakagami, T. Furukawa, K. Satoh, S. Amano, Y. Iijima, T. Koshikawa, D. Asai, K. Fukuchi, H. Takemura, T. Kanamoto, and S. Yokose
- Journal Title
  
  Medicines (Basel)
  
  Volume: 8 Issue: 7 Pages: 33-33
- DOI
  10.3390/medicines8070033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Design of substrates and inhibitors of G protein-coupled receptor kinase 2 (GRK2) based on its phosphorylation reaction2020
- Author(s)
  J.H. Kang, R. Toita, T. Kawano, M. Murata, and D. Asai
- Journal Title
  
  Amino Acids
  
  Volume: 52 Issue: 6-7 Pages: 863-870
- DOI
  10.1007/s00726-020-02864-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-17K08254, KAKENHI-PROJECT-18K12079
[Journal Article] Synthesis and Anti-HIV Activity of Sulfated Oligosaccharide-Branched β-CD2020
- Author(s)
  Mingxue, B, Chaolumen, B, Asai, D, Miyazaki, K, Yoshida, T
- Journal Title
  
  Journal of Fiber Science and Technology
  
  Volume: 76 Issue: 1 Pages: 63-71
- DOI
  10.2115/fiberst.2020-0006
- NAID
  130007789674
- ISSN
  2189-7654
- Year and Date
  2020-01-15
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08254
[Journal Article] Blood retention and antigenicity of polycarboxybetaine-modified liposomes2020
- Author(s)
  T. Ryujin, T. Shimizu, R. Miyahara, D. Asai, R. Shimazu, T. Yoshikawa, A. Kishimura, T. Mori, T. Ishida, and Y. Katayama
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 586 Pages: 119521-119521
- DOI
  10.1016/j.ijpharm.2020.119521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-17K08254
[Journal Article] Role of a long-chain alkyl group in sulfated alkyl oligosaccharides with high anti-HIV activity revealed by SPR and DLS2020
- Author(s)
  Bai Mingxue, Bai Chaolumen, K. Miyazaki, Daisuke Asai, Hiromu Takemura, T. Yoshida
- Journal Title
  
  Carbohydr. Polym.
  
  Volume: 245 Pages: 116518-116518
- DOI
  10.1016/j.carbpol.2020.116518
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05612, KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-17K08254
[Journal Article] Rapid virus inactivation by alkaline extract of leaves of Sasa sp.2020
- Author(s)
  H. Sakagami, K. Fukuchi, D. Asai, S. Terakubo, H. Takemura, M. Horiuchi, T. Fujisawa, M.
- Journal Title
  
  New Food Industry
  
  Volume: 62 Pages: 785-790
- NAID
  40022397008
- Open Access
- Data Source
  KAKENHI-PROJECT-17K08254
[Journal Article] Quantification of the Ability of Natural Products to Prevent Herpes Virus Infection2020
- Author(s)
  Fukuchi Kunihiko、Sakagami Hiroshi、Sugita Yoshiaki、Takao Koichi、Asai Daisuke、Terakubo Shigemi、Takemura Hiromu、Ohno Hirokazu、Horiuchi Misaki、Suguro Madoka、Fujisawa Tomohiro、Toeda Kazuki、Oizumi Hiroshi、Yasui Toshikazu、Oizumi Takaaki
- Journal Title
  
  Medicines
  
  Volume: 7 Issue: 10 Pages: 64-64
- DOI
  10.3390/medicines7100064
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09885, KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-17K08254
[Journal Article] Quantification of antitumor, antiviral and neuroprotective activity of twenty Kampo preparations2020
- Author(s)
  H. Shi, K. Fukuchi, D. Asai, S. Terakubo, H. Takemura, and H. Sakagami
- Journal Title
  
  New Food Industry
  
  Volume: 62 Pages: 599-607
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Effect of Fetal Bovine Serum Concentration on Lysophosphatidylcholine-mediated Proliferation and Apoptosis of Human Aortic Smooth Muscle Cells2020
- Author(s)
  Asai, D, Kawano, T, Murata, M, Nakashima, H, Toita, R, Kang, J.H
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 69 Issue: 3 Pages: 255-260
- DOI
  10.5650/jos.ess19268
- NAID
  130007804109
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08254, KAKENHI-PROJECT-18K12091, KAKENHI-PROJECT-18K19929, KAKENHI-PROJECT-17K01386, KAKENHI-PROJECT-18K12079, KAKENHI-PROJECT-19H04470
[Journal Article] Rapid virus inactivation by alkaline extract of leaves of Sasa sp.2020
- Author(s)
  H. Sakagami, K. Fukuchi, D. Asai, S. Terakubo, H. Takemura, M. Horiuchi, T. Fujisawa, M. Suguro, K. Toeda, T. Yasui, H. Oizumi, and T. Oizumi
- Journal Title
  
  New Food Industry
  
  Volume: 62 Pages: 785-790
- NAID
  40022397008
- Open Access
- Data Source
  KAKENHI-PROJECT-20K12657
[Journal Article] Elucidation of anti-HIV mechanism of sulfated cellobiose－polylysine dendrimers by SPR and DLS2020
- Author(s)
  Song Weiyue, Li Yin, T. Kanamoto, D. Asai, H. Takemura, H. Nakashima, K. Miyazaki,T, Yoshida
- Journal Title
  
  Carbohydr. Res.
  
  Volume: 495 Pages: 108084-108084
- DOI
  10.1016/j.carres.2020.108084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05612, KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-17K08254
[Journal Article] Quantification of antitumor, antiviral and neuroprotective activity of twenty Kampo preparations2020
- Author(s)
  H. Shi, K. Fukuchi, D. Asai, S. Terakubo, H. Takemura, and H. Sakagami
- Journal Title
  
  New Food Industry
  
  Volume: 62 Pages: 599-607
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08254
[Journal Article] Suppression of lysophosphatidylcholine-induced human aortic smooth muscle cell calcification by protein kinase A inhibition2019
- Author(s)
  Riki Toita, Daisuke Asai, Kentaro Otani, Takahito Kawano, Masaharu Murata, Jeong-Hun Kang
- Journal Title
  
  Lipids
  
  Volume: 54 Issue: 8 Pages: 465-470
- DOI
  10.1002/lipd.12178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01386, KAKENHI-PROJECT-17K08254, KAKENHI-PROJECT-18K12079, KAKENHI-PROJECT-18K12091, KAKENHI-PROJECT-19H04470, KAKENHI-PROJECT-18K19929
[Journal Article] Injectable polypeptide hydrogel depot system for assessment of the immune-response-inducing efficacy of sustained antigen release alone2019
- Author(s)
  Asai, D, Fukuda, T, Morokuma, K, Funamoto, D, Yamaguchi, Y, Mori, T, Katayama, Y, Shibayama, K, Nakashima, H
- Journal Title
  
  Macromol. Biosci.
  
  Volume: 19 Issue: 10
- DOI
  10.1002/mabi.201900167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08254
[Journal Article] A high-affinity peptide substrate for G protein-coupled receptor kinase 2 (GRK2)2019
- Author(s)
  Daisuke Asai, Masaharu Murata, Riki Toita, Takahito Kawano, Hideki Nakashima, Jeong-Hun Kang
- Journal Title
  
  Amino acids
  
  Volume: 51 Issue: 6 Pages: 973-976
- DOI
  10.1007/s00726-019-02735-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01386, KAKENHI-PROJECT-17K08254, KAKENHI-PROJECT-18K12079, KAKENHI-PROJECT-18K12091, KAKENHI-PROJECT-19H04470
[Journal Article] Pathogenic viruses commonly present in the oral cavity and relevant antiviral compounds derived from natural products.2018
- Author(s)
  Asai, D. and Nakashima, H.
- Journal Title
  
  Medicines(Basel)
  
  Volume: 5 Issue: 4 Pages: 120-120
- DOI
  10.3390/medicines5040120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08254
[Journal Article] A peptide inhibitor of antibody-dependent cell-mediated cytotoxicity against EGFR/folate receptor-α double positive cells2018
- Author(s)
  Koichi Sasaki, Yoshiki Miyashita, Daisuke Asai, Daiki Funamoto, Kazuki Sato, Yoko Yamaguchi, Yuji Mishima, Tadafumi Iino, Shigeo Takaishi, Jun Nagano, Akihiro Kishimura, Takeshi Mori and Yoshiki Katayama
- Journal Title
  
  Medicinal Chemistry Communications
  
  Volume: 印刷中 Issue: 5 Pages: 783-788
- DOI
  10.1039/c8md00010g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J05032, KAKENHI-PROJECT-17K08254
[Journal Article] In situ depot formation of anti-HIV fusion-inhibitor peptide in recombinant protein polymer hydrogel2017
- Author(s)
  Asai, D., Kanamoto, T., Takenaga, M., and Nakashima, H.
- Journal Title
  
  Acta Biomater.
  
  Volume: 64 Pages: 116-125
- DOI
  10.1016/j.actbio.2017.10.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08254, KAKENHI-PROJECT-15K01319
[Journal Article] Role of amino acid residues surrounding the phosphorylation site in peptide substrates of G protein-coupled receptor kinase 2 (GRK2)2017
- Author(s)
  Asai, D., Nakashima, H., and Kang, J-H.
- Journal Title
  
  Biomed. Adv.
  
  Volume: Editors' Picks (in July 2017) Pages: 22-22
- Open Access
- Data Source
  KAKENHI-PROJECT-15K01319
[Journal Article] Role of amino acid residues surrounding the phosphorylation site in peptide substrates of G protein-coupled receptor kinase 2 (GRK2)2017
- Author(s)
  Asai, D., Nakashima, H., and Kang, J.-H.
- Journal Title
  
  Biomed. Adv.
  
  Volume: Editors' Picks (in July 2017) Pages: 22-22
- Open Access
- Data Source
  KAKENHI-PROJECT-17K08254
[Journal Article] Role of amino acid residues surrounding the phosphorylation site in peptide substrates of G protein-coupled receptor kinase 2 (GRK2)2016
- Author(s)
  Asai, D., Murata, M., Toita, R., Kawano, T., Nakashima, H., and Kang, J.H.
- Journal Title
  
  Amino Acids
  
  Volume: 48 Issue: 12 Pages: 2875-2880
- DOI
  10.1007/s00726-016-2345-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460050, KAKENHI-PROJECT-15K12531, KAKENHI-PROJECT-15K01319, KAKENHI-PROJECT-15K12544, KAKENHI-PROJECT-15K16333
[Journal Article] Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor2016
- Author(s)
  Mukerji, R., Schaal, J., Li, X., Bhattacharyya, J., Asai, D., Zalutsky, M.R, Chilkoti, A., and Liu, W.
- Journal Title
  
  Biomaterials
  
  Volume: 79 Pages: 79-87
- DOI
  10.1016/j.biomaterials.2015.11.064
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460050
[Journal Article] Reversal of efflux of an anticancer drug in human drug-resistant breast cancer cells by inhibition of protein kinase Cα (PKCα) activity2016
- Author(s)
  Kim, C.W., Asai, D., Kang, J.H., Kishimura, A., Mori, T., and Katayama, Y.
- Journal Title
  
  Tumor Biol.
  
  Volume: 37 Issue: 2 Pages: 1901-1908
- DOI
  10.1007/s13277-015-3963-4
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460050, KAKENHI-PROJECT-25560202
[Journal Article] Antibody internalization into living cell via crosslinker-mediated endocytosis2015
- Author(s)
  Funamoto D, Asai D, Sato K, Yamaguchi Y, Kim CW, Sato H, Nakhaei E, Matsumoto S, Yoshikawa T, Sasaki K, Yamamoto T, Kishimura A, Mori T, and Katayama Y
- Journal Title
  
  Chem. Lett.
  
  Volume: 44 Issue: 4 Pages: 468-470
- DOI
  10.1246/cl.141157
- NAID
  130005062125
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460050
[Journal Article] Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor2015
- Author(s)
  Takenaga, M., Yamamoto, Y., Takeuchi T., Ohta, Y., Tokura, Y., Hamaguchi, A., Asai, D., Nakashima, H., Oishi, S., and Fujii, N.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 463 Issue: 3 Pages: 222-228
- DOI
  10.1016/j.bbrc.2015.05.029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01319, KAKENHI-PROJECT-26460050, KAKENHI-PROJECT-25462618
[Journal Article] Monitoring of phosphorylated peptides by radioactive assay and matrix-assisted laser desorption-ionization time-of-flight mass spectrometry2015
- Author(s)
  Kang, J.H., Asai, D., Toita, R., Kawano, T., and Murata, M.
- Journal Title
  
  Amino Acids
  
  Volume: 47 Issue: 11 Pages: 2377-2383
- DOI
  10.1007/s00726-015-2025-y
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460050, KAKENHI-PROJECT-15K12544, KAKENHI-PROJECT-15K16333
[Journal Article] Tandemly repeated peptide for cancer-specific gene carrier prepared by native chemical ligation2015
- Author(s)
  Funamoto D, Asai D, Kim CW, Nakamura Y, Lee EK, Nobori T, Niidome T, Mori T, and Katayama Y
- Journal Title
  
  Chem. Lett.
  
  Volume: 44 Issue: 4 Pages: 474-476
- DOI
  10.1246/cl.141121
- NAID
  130005062141
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460050, KAKENHI-PROJECT-25560202
[Journal Article] Expression and characterization of myristoylatedpreS1-conjugated nanocages for targeted cell delivery2014
- Author(s)
  Murata M, Piao JS, Narahara S, Kawano T, Hamano N, Kang JH, Asai D, Ugawa R, Hashizume M,
- Journal Title
  
  Protein Expressionand Purification
  
  Volume: 110 Pages: 52-56
- DOI
  10.1016/j.pep.2014.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21103001, KAKENHI-PROJECT-24300172, KAKENHI-PROJECT-25282157, KAKENHI-PROJECT-25750176, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-26460050, KAKENHI-PROJECT-15K16333
[Journal Article] Peptide substrates for G protein-coupled receptor kinase 22014
- Author(s)
  D. Asai, R. Toita, M. Murata, Y. Katayama, H. Nakashima, J.H. Kang
- Journal Title
  
  FEBS Lett.
  
  Volume: Vol.588 Issue: 13 Pages: 2129-2132
- DOI
  10.1016/j.febslet.2014.04.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23310085, KAKENHI-PROJECT-24245015, KAKENHI-PROJECT-24300172, KAKENHI-PROJECT-24790052, KAKENHI-PROJECT-25560202
[Journal Article] Liver cell-specific peptides derived from the PreS1 domain of human hepatitis B virus2014
- Author(s)
  J.H. Kang, R. Toita, D. Asai, T. Yamaoka, M. Murata
- Journal Title
  
  J Virol Methods
  
  Volume: Vol.201 Pages: 20-23
- DOI
  10.1016/j.jviromet.2014.02.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310085, KAKENHI-PROJECT-24300172, KAKENHI-PROJECT-24790052, KAKENHI-PROJECT-25870392
[Journal Article] Protein polymer hydrogels by in situ, rapid and reversible self-gelation2012
- Author(s)
  Asai, D., Xu, D., Liu, W., Garcia Quiroz, F., Callahan, D.J., Zalutsky, M.R., Craig, S.L., and Chilkoti, A
- Journal Title
  
  Biomaterials
  
  Volume: 33 Issue: 21 Pages: 5451-5458
- DOI
  10.1016/j.biomaterials.2012.03.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790052
[Journal Article] Rheological properties of cysteine-containing elastin-like polypeptides solution and hydrogels2012
- Author(s)
  Xu, D., Asai, D., Chilkoti, A., and Craig, S.L
- Journal Title
  
  Biomacromolecules
  
  Volume: 13 Issue: 8 Pages: 2315-2321
- DOI
  10.1021/bm300760s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790052
[Journal Article] Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptide in situ2012
- Author(s)
  Liu, W., McDaniel, J.R., Li, X., Asai, D., Garcia Quiroz, F., Schaal, J., Park, J.S., Zalutsky, M.R., and Chilkoti, A
- Journal Title
  
  Cancer Res
  
  Volume: 72 Pages: 5956-5965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790052
[Journal Article] Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator.2010
- Author(s)
  Asai, D., Kuramoto, M., Shoji, Y., Kang, J.H., Kodama, B.K., Kawamura, K., Mori, T., Miyoshi, H., Niidome, T., Nakashima, H., Katayama, Y.
- Journal Title
  
  J Control. Release 141
  
  Pages: 52-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Plasma protein kinase C (PKC)αas a biomarker for the diagnosis of cancers.2009
- Author(s)
  Kang, J.H. *, Asai, D. *, Toita, R., Kitazaki, H., Katayama, Y. * (*: ontributed equally)
- Journal Title
  
  Carcinogenesis 30
  
  Pages: 1927-1931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Inflammatory cell-specific gene regulation system responding to Iκ-B kinase beta activation.2009
- Author(s)
  Asai, D., Tsuchiya, A., Kang, J.H., Kawamura, K., Oishi, J., Mori, T., Niidome, T., Shoji, Y., Nakashima, H., Katayama, Y.
- Journal Title
  
  J. Gene Med. 11
  
  Pages: 624-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Inflaminatory cell-specific gene regulation system responding to Iκ-Bkinase beta activation2009
- Author(s)
  Asai, D., et al.
- Journal Title
  
  J.Gene Med.
  
  Pages: 624-631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals.2009
- Author(s)
  Kang, J.H., Toita, R., Tomiyama, T., Oishi, J., Asai, D., Mori, T., Niidome, T., Katayama, Y.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 19
  
  Pages: 6082-6086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Regulation of transgene expression in tumor cells by exploiting endogenous intracellular signals.2009
- Author(s)
  Asai, D., Kang, J.H., Toita, R., Tsuchiya, A., Niidome, T., Nakashima, H., Katayama, Y.
- Journal Title
  
  Nanoscale Res. Lett. 4
  
  Pages: 229-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Molecular mechanism of caspase-3-induced gene expression of polyplexes formed from polycations grafted with cationic substrate peptides.2009
- Author(s)
  Kawamura, K., Kuramoto, M., Mori, T., Toita, R., Oishi, J., Sato, Y., Kang, J.H., Asai, D., Niidome, T., Katayama, Y.
- Journal Title
  
  J. Biomater. Sci. Polym. Ed. 20
  
  Pages: 967-980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator2009
- Author(s)
  Asai, D., et al.
- Journal Title
  
  J.Control. Release (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Drug delivery system based on responses to an HIV infectious signal.2008
- Author(s)
  Asai, D., Kodama, B.K., Shoji, Y., Nakashima, H., Kawamura, K., Oishi, J., Kuramoto, M., Niidome, T., Katayama, Y.
- Journal Title
  
  Med. Chem. 4
  
  Pages: 386-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Direct measure of fluorescence intensity for efficient receptor-binding assay:Conjugates of ethinylcarboxyestradiol and 5(and 6)-carboxyfluorescein via a, w-diaminoalkanes as a tracer for estrogen receptor.2008
- Author(s)
  Asai, D., Tokunaga, T., Kondo, K., Kawaguchi, T., Takayanagi, S., Shinmyozu, T., Nakai, M., Yakabe, Y., Shimohigashi, Y.
- Journal Title
  
  J. Biochem. 143
  
  Pages: 781-792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Drug delivery system based on responses to an HIV infectious signal.2008
- Author(s)
  Asai D, et al.
- Journal Title
  
  Med. Chem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790123
[Journal Article] Regulation of Transgene Expression in Tumor Cells by Exploiting Int racellular Signals2008
- Author(s)
  Asai D, et.al.
- Journal Title
  
  Nanoscale Res. Lett 4
  
  Pages: 229-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Correlation between phosphorylation ratios by MALDI-TOF MS analysis and enzyme kinetics.2008
- Author(s)
  Kang, J.H., Kuramoto, M., Tsuchiya, A., Toita, R., Asai, D., Sato, T.Y., Mori, T., Niidome, T., Katayama, Y.
- Journal Title
  
  Eur J. Mass Spectrom. 14
  
  Pages: 261-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Ca activation in cancer cells.2008
- Author(s)
  Kang, J.H., Asai, D., Kim, J.H., Mori, T., Toita, R., Tomiyama, T., Asami, Y., Oishi, J., Sato, Y., Niidome, T., Jun, B., Nakashima, H., Katayama, Y.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 14906-14907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] 酵素の基質ペプチドを用いて人工的に遺伝子発現を制御する2008
- Author(s)
  浅井大輔
- Journal Title
  
  Peptide Newsletter Japan 67
  
  Pages: 8-11
- Data Source
  KAKENHI-PROJECT-18790123
[Journal Article] Disordered Cell-specific Gene Regulation System for Suicide Gene Therapy2008
- Author(s)
  Asai D, et.al.
- Journal Title
  
  Jpn. J. Chemother 56
  
  Pages: 538-542
- NAID
  10022594885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Disordered cell-specific gene regulation system for suicide gene therapy.2008
- Author(s)
  Asai, D., Nakashima, H.
- Journal Title
  
  Jpn. J. Chemother 56
  
  Pages: 538-542
- NAID
  10022594885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Direct measure of fluorescence intensity for efficient receptor-binding assay: Conjugates of ethinylcarboxyestradiol and 5(and 6)-carboxyfluorescein via α, ω-diaminoalkanes as a tracer for etrogen receptor.2008
- Author(s)
  Asai D, et al.
- Journal Title
  
  J. Biochem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790123
[Journal Article] A short peptide is a protein kinase C (PKC) a-specific substrate.2008
- Author(s)
  Kang, J.H. *, Asai, D. *, Yamada, S. *, Toita, R., Oishi, J., Mori, T., Niidome, T., Katayama, Y. (*: contributed equally)
- Journal Title
  
  Proteomics 8
  
  Pages: 2006-2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule.
- Author(s)
  Kang, J.H., Oishi, J., Kim, J.H., Ijuin, M., Toita, R., Jun, B., Asai, D., Mori, T., Niidome, T., Tanizawa, K., Kuroda, S., Katayama, Y.
- Journal Title
  
  Nanomedicine (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790042
[Journal Article] Progress in current non-viral carriers for gene delivery.
- Author(s)
  Shoji-Moskowitz, Y, Asai, D., Kodama, K., Katayama, Y., Nakashima, H.
- Journal Title
  
  Frontiers in Medicinal Chemistry (in press)
- Data Source
  KAKENHI-PROJECT-20790042
[Patent] 抗黄色ブドウ球菌剤及び化合物の使用2023
- Inventor(s)
  霜鳥慈岳、金本大成、浅井大輔
- Industrial Property Rights Holder
  霜鳥慈岳、金本大成、浅井大輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-010589
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-20K12657
[Patent] 単純ヘルペス不活性化剤2021
- Inventor(s)
  相見光、進藤大輝、坂上宏、福地邦彦、浅井大輔
- Industrial Property Rights Holder
  相見光、進藤大輝、坂上宏、福地邦彦、浅井大輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-068146
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K12657
[Patent] ヒト免疫不全ウイルス不活性化剤2021
- Inventor(s)
  相見光、進藤大輝、坂上宏、福地邦彦、浅井大輔
- Industrial Property Rights Holder
  相見光、進藤大輝、坂上宏、福地邦彦、浅井大輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-068147
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K12657
[Patent] Rho-キナーゼの新規基質ペプチド2009
- Inventor(s)
  片山佳樹、姜貞勲、浅井大輔
- Industrial Property Rights Holder
  片山佳樹、姜貞勲、浅井大輔
- Industrial Property Number
  2009-211147
- Filing Date
  2009
- Acquisition Date
  2009
- Data Source
  KAKENHI-PROJECT-20790042
[Patent] 蛍光リガンド及び化学物質のアンドロゲン受容体への結合強度測定方法2008
- Inventor(s)
  下東康幸、中井誠、浅井大輔、矢可部芳州
- Industrial Property Rights Holder
  下東康幸、中井誠、浅井大輔、矢可部芳州
- Filing Date
  2008
- Acquisition Date
  2008
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] リグニンスルホン酸塩によるウイルス不活性化に関する検討2022
- Author(s)
  相見光、吉川裕治、福地邦彦、浅井大輔、越川拓郎、坂上宏
- Organizer
  第89回紙パルプ研究発表会
- Data Source
  KAKENHI-PROJECT-20K12657
[Presentation] 光学活性な3-メチル-4-アルカノリド類の合成と香気特性の評価2021
- Author(s)
  角咲希、霜鳥慈岳、小川熟人、宮腰哲雄、金本大成、浅井大輔
- Organizer
  第65回香料・テルペンおよび精油化学に関する討論会
- Data Source
  KAKENHI-PROJECT-20K12657
[Presentation] CRISPR/Cas9システムを用いた黄色ブドウ球菌溶血毒素産生の抑制2021
- Author(s)
  池田奈々、今関義経、梶川瑞穂、浅井大輔、金本大成
- Organizer
  第104回日本細菌学会関東支部総会
- Data Source
  KAKENHI-PROJECT-20K12657
[Presentation] 次世代ワクチンの基盤開発研究：インジェクタブルゲル抗原製剤を用いたアプローチ2019
- Author(s)
  浅井大輔、福田靖、諸熊一則、船本大起、山口優子、森健、片山佳樹、柴山恵吾、中島秀喜
- Organizer
  第41回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-17K08254
[Presentation] 抗体産生および抗体特性に及ぼす抗原徐放単独寄与の解明2019
- Author(s)
  浅井大輔、福田靖、諸熊一則、船本大起、山口優子、森健、片山佳樹、柴山恵吾、中島秀喜
- Organizer
  第35回日本ＤＤＳ学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08254
[Presentation] 近接双性イオンポリマーの低抗原性の評価2019
- Author(s)
  龍神尭昌、宮原涼、浅井大輔、岸村顕広、森健、片山佳樹
- Organizer
  第56回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-17K08254
[Presentation] 注射型抗HIVペプチドデポ製剤の開発2017
- Author(s)
  浅井大輔, 金本大成, 寺久保繁美, Ashutosh Chilkoti, 武永美津子, 中島秀喜
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15K01319
[Presentation] Protection from off-target ADCC by using peptide inhibitors2017
- Author(s)
  Mori, T., Sasaki, K., Miyashita, Y., Asai, D., Harada, M., Kishimura, A. and Katayama, Y.
- Organizer
  The 2nd international symposium on biofunctional chemistry (ISBC2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08254
[Presentation] 注射型抗HIVペプチドデポ製剤の開発2017
- Author(s)
  浅井大輔, 金本大成, 寺久保繁美, Ashutosh Chilkoti, 武永美津子, 中島秀喜
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08254
[Presentation] 新規合成KSP阻害剤のヒト卵巣がんに対する抗腫瘍効果2016
- Author(s)
  武永美津子、竹内智起、山本有貴、都倉享恵、新美純、濱口明美、太田有紀、浅井大輔、大石真也、中島秀喜、藤井信孝
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  パシフィコ横浜（横浜市西区）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] 人工エラスチンポリペプチド：破傷風トキソイドデポ製剤への最適化2016
- Author(s)
  浅井大輔、福田靖、諸熊一則、山口優子、Ashutosh Chilkoti、柴山恵吾、中島秀喜
- Organizer
  第３２回日本ＤＤＳ学会学術集会
- Place of Presentation
  グランシップ（静岡県静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] 新規合成KSP阻害剤のヒト卵巣がんに対する抗腫瘍効果2016
- Author(s)
  武永美津子、竹内智起、山本有貴、都倉享恵、新美純、濱口明美、太田有紀、浅井大輔、大石真也、中島秀喜、藤井信孝
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  パシフィコ横浜、横浜市西区
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K01319
[Presentation] 人工エラスチンポリペプチド：破傷風トキソイドデポ製剤への最適化2016
- Author(s)
  浅井大輔、福田靖、諸熊一則、山口優子、Ashutosh Chilkoti、柴山恵吾、中島秀喜
- Organizer
  第３２回日本ＤＤＳ学会学術集会
- Place of Presentation
  グランシップ（静岡県静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K01319
[Presentation] 破傷風トキソイドを用いた人工エラスチン蛋白のアジュバントとしての可能性2015
- Author(s)
  福田靖、浅井大輔、山口優子、諸熊一則、Ashutosh Chilkoti、中島秀喜、柴山恵吾
- Organizer
  第１９回日本ワクチン学会学術集会
- Place of Presentation
  名鉄犬山ホテル、愛知県犬山市
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-15K01319
[Presentation] インジェクタブル人工エラスチンゲルによる抗HIVペプチドのデポ製剤化2015
- Author(s)
  浅井大輔、金本大成、寺久保繁美、Ashutosh Chilkoti、武永美津子、中島秀喜
- Organizer
  第３７回日本バイオマテリアル学会大会
- Place of Presentation
  京都テルサ（京都市南区）
- Year and Date
  2015-11-09
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] マクロファージを選択的に認識する機能性ナノ分子の創製2015
- Author(s)
  姜貞勲、戸井田力、浅井大輔、村田正治
- Organizer
  第８８回日本生化学大会/第３８回日本分子生物学会合同大会（BMB2015）
- Place of Presentation
  神戸ポートアイランド（神戸市中央区）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] 破傷風トキソイドを用いた人工エラスチン蛋白のアジュバントとしての可能性2015
- Author(s)
  福田靖、浅井大輔、山口優子、諸熊一則、Ashutosh Chilkoti、中島秀喜、柴山恵吾
- Organizer
  第１９回日本ワクチン学会学術集会
- Place of Presentation
  名鉄犬山ホテル（愛知県犬山市）
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] インジェクタブル人工エラスチンによる抗原デポ剤：破傷風トキソイドの徐放効果の解析2015
- Author(s)
  浅井大輔、福田靖、諸熊一則、Ashutosh Chilkoti、柴山恵吾、中島秀喜
- Organizer
  第３１回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] インジェクタブル人工エラスチンによる抗原デポ剤：破傷風トキソイドの徐放効果の解析2015
- Author(s)
  浅井大輔、福田靖、諸熊一則、Ashutosh Chilkoti、柴山恵吾、中島秀喜
- Organizer
  第３１回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル、東京都新宿区
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K01319
[Presentation] インジェクタブル人工エラスチンゲルによる抗HIVペプチドのデポ製剤化2015
- Author(s)
  浅井大輔、金本大成、寺久保繁美、Ashutosh Chilkoti、武永美津子、中島秀喜
- Organizer
  第３７回日本バイオマテリアル学会大会
- Place of Presentation
  京都テルサ、京都市南区
- Year and Date
  2015-11-09
- Data Source
  KAKENHI-PROJECT-15K01319
[Presentation] Preparation of cancer-signal-responsive gene carrier via native chemical ligation2013
- Author(s)
  Funamoto, D., Mori, T., Asai, D., Niidome, T., and Katayama, Y
- Organizer
  4th Asian Biomaterials Congress
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] ネイティブケミカルライゲーションによるがん増殖シグナル応答性遺伝子キャリアの作製2013
- Author(s)
  船本大起、森健、浅井大輔、新留琢郎、片山佳樹
- Organizer
  第62回高分子学会年次大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] ネイティブケミカルライゲーションによる癌増殖シグナル応答性遺伝子キャリアの作製2013
- Author(s)
  船本大起、森健、浅井大輔、新留琢郎、片山佳樹
- Organizer
  第６２回高分子学会
- Place of Presentation
  京都国際会館, 京都市左京区
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] Preparation of cancer-signal-responsive gene carrier via native chemical ligation2013
- Author(s)
  Funamot D, Mori T, Asai D, Niidome T, and Katayama Y
- Organizer
  4th Asian Biomaterials Congresss
- Place of Presentation
  Hong Kong University of Science and Technology, Hong Kong, China
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 新規合成KSP阻害剤の抗腫瘍効果に関する研究2013
- Author(s)
  武永美津子、竹内智紀、都倉享恵、濱口明美、太田有紀、浅井大輔、大石真也、中島秀喜、藤井信孝
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 新規合成KSP阻害剤の抗腫瘍効果に関する研究2013
- Author(s)
  武永美津子、竹内智紀、都倉享恵、濱口明美、太田有紀、浅井大輔、大石真也、中島秀喜、藤井信孝
- Organizer
  第２９回日本DDS学会学術集会
- Place of Presentation
  京都テルサ, 京都市南区
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 人工エラスチンポリペプチドゲルの薬物徐放性の解析2012
- Author(s)
  浅井大輔、中島秀喜、Ashutosh Chilkoti
- Organizer
  日本バイオマテリアル学会シンポジウム2012
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] インジェクタブルDDSを実現する人工エラスチンポリペプチドゲル2012
- Author(s)
  浅井大輔、中島秀喜、Ashutosh Chilkoti
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 遺伝子工学を用いた人工プロテインポリマーハイドロゲル2012
- Author(s)
  浅井大輔、中島秀喜、Ashutosh Chilkoti
- Organizer
  第61回高分子学会年次大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] Preclinical studies on tumor retention, antitumor efficacy and toxicity of thermally responsive polypeptide-based radionuclide intratumoral depot in nude mice2012
- Author(s)
  Liu, W., McDaniel, J.R., Li, X., Asai, D., Zalutsky, M.R., and Chilkoti, A
- Organizer
  American Association for Cancer Research Annual Meeting 2012
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 薬物デポを指向した人工蛋白質性注射ゲルの合理的設計2012
- Author(s)
  浅井大輔、中島秀喜、Ashutosh Chilkoti
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] インジェクタブルDDSを実現する人工エラスチンポリペプチドゲル2012
- Author(s)
  浅井大輔　ほか
- Organizer
  第２８回日本ＤＤＳ学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 次世代医用材料の開発 : 薬物徐放のための生体吸収性注射ゲル2012
- Author(s)
  浅井大輔、金本大成、福田靖、寺久保繁美、諸熊一則、柴山恵吾、中島秀喜
- Organizer
  第72回神奈川県感染症医学会
- Place of Presentation
  横浜
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] Thermally-responsive Elastin-like polypeptide engineered to locally deliver radionuclide payload leads to complete regression of solid tumor2012
- Author(s)
  Liu, W., McDaniel, J.R., Li, X., Asai, D., Zalutsky, M.R., and Chilkoti, A
- Organizer
  9th World Biomaterials Congress
- Place of Presentation
  Chengdu, China
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 薬物デポを指向した人工蛋白質性注射ゲルの合理的設計2012
- Author(s)
  浅井大輔　ほか
- Organizer
  第８５回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] Inflammatory signal-sensing polymer responding to IK-B kinase beta act ivat ion.2009
- Author(s)
  Asai, D., Tsuchiya, A., Kang, J.H., Niidome, T., Nakashima, H., Ka tayama, Y.
- Organizer
  8th International Symposium on Front iers in Biomedical Polymers (FBPS2009)
- Place of Presentation
  Mishima
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] 疾患細胞特異的な遺伝子発現制御法の開発-第2報2009
- Author(s)
  浅井大輔, ほか
- Organizer
  第65回神奈川県感染症医学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] Specific transgene expression in virus-infected cells by a virus protease-cleavable transcription suppressor2009
- Author(s)
  Asai, D., et al.
- Organizer
  BIT Life Sciences' 2^<nd> Annual Protein and Peptide Conference (PepCon-2009)
- Place of Presentation
  South Korea
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] Specific transgene expression in virus-infected cells by a virus protease-cleavable transcription suppressor.2009
- Author(s)
  Asai, D., Kuramo to, M., Kang, J.H., Niidome, T., Miyoshi, H., Nakashima, H., Katayama, Y.
- Organizer
  BIT Life Sciences' 2nd Annual Protein and Peptide Conference (PepCon-2009)
- Place of Presentation
  Seoul, South Korea
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] Inflammatory signal-sensing polymer responding to Iκ-B kinase bet a achvation2009
- Author(s)
  Asai, D., et al.
- Organizer
  8^<th> International Symposium on Frontiers in Biomedical Polyxners (FBPS2009)
- Place of Presentation
  Mishima
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] 疾患細胞特異的な遺伝子発現制御法の開発-第2報2009
- Author(s)
  浅井大輔、姜貞勲、三好洋、片山佳樹、中島秀喜
- Organizer
  第65回神奈川県感染症医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] 抗ウイルス薬開発の新戦略- ウイルス感染細胞特異的な遺伝子発現制御法の創出2008
- Author(s)
  浅井大輔, ほか
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] HIV感染シグナルに応答する遺伝子発現制御材料の開発2008
- Author(s)
  浅井大輔、倉本政則、森健、新留琢郎、東海林洋子、片山佳樹、中島秀喜
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] Tumor intracellular signal- targeting by application of speci ficsubstrate peptide for protein kinase Cα2008
- Author(s)
  Asai, D., et.al.
- Organizer
  17^<th> Meeting of Methods in Protein Structure Analysis
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] Tumor intracellular signal-targeting by application of specific substrate peptide for protein kinasecc2008
- Author(s)
  Asai, D., Knag, J.H., Toita, R., Tomiyama, T., Mori, T., Niidome, T., Nakashima, H., Katayama, Y.
- Organizer
  17' Meeting of Methods in Protein Structure Analysis
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] 抗ウィルス薬開発の新戦略-ウイルス感染細胞特異的な遺伝子発現制御法の創出2008
- Author(s)
  浅井大輔、三好洋、中島秀喜
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20790042
[Presentation] 自殺遺伝子治療を目指した疾患細胞選択的な遺伝子発現制御法D-RECSの開発2007
- Author(s)
  浅井大輔ほか
- Organizer
  第55回日本化学療法学会総会
- Place of Presentation
  仙台
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18790123
[Presentation] ウイルス感染細胞選択的な遺伝子発現制御法の開発2007
- Author(s)
  浅井大輔, ほか
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-18790123
[Presentation] 内在性のIgGにより細胞毒性を誘導できるペプチド性化合物の開発
- Author(s)
  船本大起、パクサウン、森健、浅井大輔、岸村顕広、佐藤一紀、山口容子、片山佳樹
- Organizer
  第６３回高分子学会年次大会
- Place of Presentation
  名古屋国際会議場、名古屋市熱田区
- Year and Date
  2014-05-28 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] Development of peptide-based compounds for cytotoxicity induction utilizing ubiquitous endogenous IgG
- Author(s)
  Funamoto, D., Park, S., Mori, T., Asai, D., Kishimura, A., Sato, K., Yamaguchi, Y., and Katayama, Y
- Organizer
  The IUMRS International Conference in Asia 2014
- Place of Presentation
  Fukuoka University, Fukuoka
- Year and Date
  2014-08-24 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] 次世代医用材料の開発：薬物徐放のための生体吸収性注射ゲル
- Author(s)
  浅井大輔　ほか
- Organizer
  第７２回神奈川県感染症医学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790052
[Presentation] 新規KSP阻害剤の抗腫瘍効果に関する研究（第２報）
- Author(s)
  武永美津子、竹内智紀、都倉享恵、濱口明美、山本有貴、太田有紀、浅井大輔、中島秀喜、大石真也、藤井信孝
- Organizer
  第３０回日本DDS学会学術集会
- Place of Presentation
  慶応大学薬学部、東京都港区
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-26460050
[Presentation] ケミカルバイオロジー分子ツールの開発：ROCK2およびGRK2選択的ペプチド性基質
- Author(s)
  浅井大輔、戸井田力、土谷享、村田正治、片山佳樹、姜貞勲、中島秀喜
- Organizer
  第８７回日本生化学大会
- Place of Presentation
  京都国際会館、京都市左京区
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460050

1. KATAYAMA Yoshiki (70284528)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. MORI Takeshi (70335785)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OHUCHIDA Kenoki (20452708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Nakashima Hideki (20192669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. FUJII Nobutaka (60109014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KANAMOTO Taisei (20260755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Yoshida Takashi (40166955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 福田靖 (80270651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 武永美津子 (10236490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 有戸光美 (00509911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 馬場英司 (00315475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 宮崎健輔 (50636610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. MOROKUMA Kazunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. SHIBAYAMA Keigo

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. KANG JEONG-HUN

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
16. TAKAO Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. LIU Xiaohui

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. TOITA Riki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. MIYANO Kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 橋爪誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 坂上宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 杉田義昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Asai Daisuke 浅井 大輔

ASAI Daisuke 浅井 大輔

Research Projects

Research Products

Co-Researchers

Development of a depot formulation that senses the bacterial infection environment and releases antimicrobial peptide drugsPrincipal Investigator

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Elucidation of unresolved anti-HIV mechanism of sulfated polysaccharides

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Development of antimicrobial agents: challenges by artificial multifunctional biopolymersPrincipal Investigator

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Ultra-sensitive detection method of membrane antigens and its application to cancer companion diagnosis

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Development of molecular bases of next generation vaccine: Approach from antigen depot delivery systemPrincipal Investigator

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Development of anti HIV peptide applying multifunctional polypeptide

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Proteomic analysis for drug-resistant mechanisms of Staphylococcus aureus

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Development of novel depot-forming bioabsorbable recombinant elastomers for immunoresponse augmentationPrincipal Investigator

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Peptide microarray for prognosis of cancer chemotherapy

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Development of novel platform for injectable in vivo drug delivery systemPrincipal Investigator

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Development of inflammatory cell-specific gene regulation system for gene therapeutic strategyPrincipal Investigator

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炎症細胞特異的な遺伝子送達を目指した遺伝子キャリアーの創製Principal Investigator

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[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術, 第7章 ペプチド医薬品の製剤化技術 第２節 抗HIVペプチドのデポ製剤化2017

Author(s)

Total Pages

Asai Daisuke 浅井大輔

ASAI Daisuke 浅井大輔

[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術, 第7章　ペプチド医薬品の製剤化技術　第２節　抗HIVペプチドのデポ製剤化2017

[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術, 第7章　ペプチド医薬品の製剤化技術　第２節　抗HIVペプチドのデポ製剤化2017