Takahashi Satoru 高橋悟

… Alternative Names

高橋悟タカハシサトル

TAKAHASHI Satoshi 高橋悟

TAKAHASHI Satoru 高橋悟

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Researcher Number	10431404
Other IDs
Affiliation (Current)	2025: 旭川医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 旭川医科大学, 医学部, 教授 2022 – 2023: 旭川医科大学, 医学部, 教授 2021: 旭川医科大学, 医学部, 准教授 2019 – 2020: 旭川医科大学, 医学部, 講師 2015: 旭川医科大学, 医学部, 講師 … More 2015: 国立大学法人旭川医科大学, 医学部小児科学, 講師 2010 – 2013: 旭川医科大学, 医学部, 講師 2007: Asahikawa Medical College, 医学部, 助教 2006: 旭川医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords	Principal Investigator てんかん / 既承認薬ライブラリー / GLUT1欠損症 / グルコーストランスポーター / ドラッグリポジショング / 既承認薬 / 治療 / 知的障害 / 炎症 / けいれん … More / 神経変性 / cyclin-dependent kinase 5 / ノックアウトマウス / 神経細胞移動 / 脳形成異常 / モデルマウス / iPS細胞 / GLUT1 / ドラッグ・リポジショニング / 創薬 / ケトン食療法 / スクリーニング / レポーター遺伝子 / 治療薬 / ハプロ不全 / 運動障害 / グルコーストランスポーター１ / tissue-type plasminogen activator / モデル動物 / 脳・神経 / Cdk5 / 皮質形成異常 / Cyclin-dependent kinase 5 … More Except Principal Investigator mTOR阻害剤 / 脳オルガノイド / 神経細胞 / iPS細胞 / MECP2重複症候群 / インプリンティング / モデル動物 / IGFBP3 / MeCP2 / レット症候群 / 発達障害 / エピゲノム Less

mTORを標的としたMECP2重複症候群の治療薬探求－疾患特異的iPS細胞を用いた薬効評価－
- Principal Investigator
  
  赤羽裕一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Asahikawa Medical College
ハプロ不全で発症するGLUT1欠損症の治療薬開発：既承認薬ライブラリーからの選別Principal Investigator
- Principal Investigator
  
  高橋悟
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Asahikawa Medical College
Screening of potent GLUT1 activators from FDA-approved drug libraryPrincipal Investigator
- Principal Investigator
  
  Takahashi Satoru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Asahikawa Medical College
A study for molecular pathomechanism of neurodevelopment disorders causing epigenetic dysfunction
- Principal Investigator
  
  Masayuki Itoh
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Center of Neurology and Psychiatry
Impact of epileptic seizures on developing brain: a study using forebrain-specific Cdk5 conditional knockout micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Satoru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Asahikawa Medical College
脳形成異常の病態解明-前脳特的CDK5欠損マウスをモデルとして-Principal Investigator
- Principal Investigator
  
  高橋悟
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Pediatrics
- Research Institution
  Asahikawa Medical College

All 2023 2021 2020 2019 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Associations of severity with biochemical parameters in glucose transporter 1 deficiency syndrome.2023
- Author(s)
  Nabatame S, Tanigawa J, Tominaga K, Kagitani-Shimono K, Yanagihara K, Imai K, Ando T, Tsuyusaki Y, Araya N, Matsufuji M, Natsume J, Yuge K, Bratkovic D, Arai H, Okinaga T, Matsushige T, Azuma Y, Ishihara N, Miyatake S, Kato M, Matsumoto N, Okamoto N, Takahashi S, Hattori S, Ozono K
- Journal Title
  
  J Neurol Sci
  
  Volume: 447 Pages: 120597-120597
- DOI
  10.1016/j.jns.2023.120597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07908, KAKENHI-PROJECT-22K15952, KAKENHI-PROJECT-19K08322, KAKENHI-PROJECT-23K27520
[Journal Article] The role of molecular analysis of SLC2A1 in the diagnostic workup of glucose transporter 1 deficiency syndrome.2020
- Author(s)
  Takahashi S, Tanaka R, Takeguchi R, Kuroda M, Akaba Y, Ito Y
- Journal Title
  
  J Neurol Sci
  
  Volume: 416 Pages: 117041-117041
- DOI
  10.1016/j.jns.2020.117041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08268
[Journal Article] A novel mutation in SLC2A1 gene causing GLUT-1 deficiency syndrome in a young adult patient.2019
- Author(s)
  Ustyol A, Takahashi S, Hatipoglu HU, Duman MA, Elevli M, Duru HNS
- Journal Title
  
  Turk J Pediatr
  
  Volume: 61 Issue: 6 Pages: 946-948
- DOI
  10.24953/turkjped.2019.06.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08268
[Journal Article] Expression of Astrocyte-related Receptors in Cortical Dysplasia with Intractable Epilepsy2014
- Author(s)
  Sukigara S, Dai H, Nabatame S, Otsuki T, Hanai S, Honda R, Saito T, Nakagawa E, Kaido T, Sato N, Kaneko Y, Takahashi A, Sugai K, Saito Y, Sasaki M, Goto Y, Koizumi S, Itoh M
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 73 Pages: 798-806
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390270
[Journal Article] Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPAR-gamma agonist improves neuronal loss and early lethality.2014
- Author(s)
  Utreras E, Hamada R, Prochazkova M, Terse A, Takahashi S, Ohshima T, Kulkarni AB
- Journal Title
  
  J Neuroinflammation
  
  Volume: in press Issue: 1
- DOI
  10.1186/1742-2094-11-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591118
[Journal Article] Hypomyelination Phenotype caused by impaired differentiation of oligodendrocytes in Emxl-cre mediated Cdk5 conditional knockout mice.2011
- Author(s)
  Xe H, Takahashi S, Suzuki H, Hashikawa T, Kulkarni AB, Mikoshiba K, Ohshima T
- Journal Title
  
  Neurochemical Research
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591118
[Journal Article] Hypomyelination Phenotype Caused by Impaired Differentiation of Oligodendrocytes in Emx1-cre Mediated Cdk5 Conditional Knockout Mice2011
- Author(s)
  He X, Takahashi S, Suzuki H, Hashikawa T, Kulkarni AB, Mikoshiba K, Ohshima T
- Journal Title
  
  Neurochem Res
  
  Volume: 36(7) Issue: 7 Pages: 1293-1303
- DOI
  10.1007/s11064-010-0391-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220007, KAKENHI-PROJECT-22591118
[Journal Article] Phosphorylation of P27Kipl at Thr187 by Cyclin-dependent Kinase 5 Modulates Neural Stem Cell Differentiation.2010
- Author(s)
  Zheng YL, Li BS, Rudrabhatla P, Shuk la V, Amin ND, Maric D, Kesavapany S, Kanungo 」, Pareek TK, Takahashi S, Grant P, Kulkarni AB, Pant HC
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: Vol.21 Pages: 3601-3614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591118
[Presentation] グルコーストランスポーター１欠損症と鑑別を要する病態について2021
- Author(s)
  高橋　悟、竹口　諒、黒田真実、田中亮介
- Organizer
  第35回日本小児神経学会北海道地方会
- Data Source
  KAKENHI-PROJECT-19K08268
[Presentation] PPARg agonist treatment of neurodegeneration in Cyclin-dependent kinase 5 conditional KO mice2013
- Author(s)
  Hamada R, Takahashi S, Kulkarni AB, Ohshima T
- Organizer
  Neuro
- Data Source
  KAKENHI-PROJECT-22591118
[Presentation] Inhibition of tissue-type plasminogen activator expression does not ameliorate neuro-inflammation in forebrain-specific Cdk5 conditional knockout mice.2012
- Author(s)
  Utreras E, Prochazkova M, Terse A, Takahashi S, Kulkarni AB
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-22591118
[Presentation] Inhibition of tissue-type plasminogen activator expression does not ameliorate neuro-inflammation in forebrain-specific Cdk5 conditional knockout mice2012
- Author(s)
  Utreras E, Prochazkova M, Terse A, Takahashi S, Kulkarni AB
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-22591118
[Presentation] PPARg agonist treatment of neurodegeneration in Cyclin-dependent kinase 5 conditional KO mice
- Author(s)
  Hamada R, Takahashi S, Kulkarni AB, Ohshima T
- Organizer
  Neuro 2013（第36回日本神経科学大会、第56回日本神経化学会大会、第23回日本神経回路学会大会　合同大会）
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22591118

1. Masayuki Itoh (50243407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. MATSUDA Junichirou (60181731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 辻村啓太 (60588474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 赤羽裕一 (50906401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 御子柴克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Satoru 高橋 悟

高橋 悟 タカハシ サトル

TAKAHASHI Satoshi 高橋 悟

TAKAHASHI Satoru 高橋 悟

Research Projects

Research Products

Co-Researchers

mTORを標的としたMECP2重複症候群の治療薬探求－疾患特異的iPS細胞を用いた薬効評価－

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ハプロ不全で発症するGLUT1欠損症の治療薬開発：既承認薬ライブラリーからの選別Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Screening of potent GLUT1 activators from FDA-approved drug libraryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study for molecular pathomechanism of neurodevelopment disorders causing epigenetic dysfunction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Impact of epileptic seizures on developing brain: a study using forebrain-specific Cdk5 conditional knockout micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳形成異常の病態解明-前脳特的CDK5欠損マウスをモデルとして-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Associations of severity with biochemical parameters in glucose transporter 1 deficiency syndrome.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of molecular analysis of SLC2A1 in the diagnostic workup of glucose transporter 1 deficiency syndrome.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel mutation in SLC2A1 gene causing GLUT-1 deficiency syndrome in a young adult patient.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of Astrocyte-related Receptors in Cortical Dysplasia with Intractable Epilepsy2014

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPAR-gamma agonist improves neuronal loss and early lethality.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypomyelination Phenotype caused by impaired differentiation of oligodendrocytes in Emxl-cre mediated Cdk5 conditional knockout mice.2011

Author(s)

Journal Title

Data Source

[Journal Article] Hypomyelination Phenotype Caused by Impaired Differentiation of Oligodendrocytes in Emx1-cre Mediated Cdk5 Conditional Knockout Mice2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphorylation of P27Kipl at Thr187 by Cyclin-dependent Kinase 5 Modulates Neural Stem Cell Differentiation.2010

Author(s)

Journal Title

Data Source

Takahashi Satoru 高橋悟

高橋悟タカハシサトル

TAKAHASHI Satoshi 高橋悟

TAKAHASHI Satoru 高橋悟