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Motegi Atsushi  茂木 厚

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… Alternative Names

茂木 厚  モテギ アツシ

MOTEGI Atsushi  茂木 厚

MOTEGI Atushi  茂木 厚

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Researcher Number 10433997
Affiliation (Current) 2025: 国立研究開発法人国立がん研究センター, 東病院, 医員
Affiliation (based on the past Project Information) *help 2016 – 2019: 国立研究開発法人国立がん研究センター, 東病院, 医員
2012 – 2014: 独立行政法人国立がん研究センター, 東病院, 医員
2007 – 2008: Tokyo Women's Medical University, 医学部, 助教
Review Section/Research Field
Principal Investigator
Radiation science
Except Principal Investigator
Radiation science
Keywords
Principal Investigator
放射線感受性 / HPV / 中咽頭癌 / 網羅的解析 / 治療感受性予測 / 癌 / 遺伝子 / 放射線 / 遺伝子変異 / cell free DNA … More / p53 / 頭頸部扁平上皮癌 / 低侵襲バイオマーカー / 腫瘍特異的遺伝子 / HPV関連がん / 放射線治療感受性 / バイオマーカー / 網羅的遺伝子解析 / 放射感受性予測 / 頭頸部癌 / 免疫組織化学 / がん幹細胞 / 放射線生物学 / 放射線治療 / p16 / CD44 / がん幹細胞マーカー / 遺伝子発現 / stem cell factor / 自己リン酸化 / チロシンキナーゼ / A549 / c-KIT / STI571 … More
Except Principal Investigator
LET / DNA損傷修復 / RBE / ブラックピーク / 生物学的効果比 (RBE) / 拡大ブラッグピーク / 感受性増感 / 陽子線 / 放射線応答 / 放射線感受性 / ブラッグピーク / 細胞応答 / 陽子線治療 / 放射線生物 / 放射線治療 Less
  • Research Projects

    (4 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (4 People)
  •  Prediction of radiosensitivity of head and neck cancer using comprehensive genomic analysisPrincipal Investigator

    • Principal Investigator
      Motegi Atsushi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Cancer Center Japan
  •  Radiobiological analysis for new technological development of proton beam therapy

    • Principal Investigator
      Akimoto Tetsuo
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Cancer Center Japan
  •  Cancer stem cell and radiosensitivity.Principal Investigator

    • Principal Investigator
      MOTEGI Atsushi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      National Cancer Center Japan
  •  Influence of radiation-induced KIT autophosphorylation on radiosensitivity of human cancer cell lines.Principal Investigator

    • Principal Investigator
      MOTEGI Atushi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Women's Medical University

All 2019 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Induction TPF chemotherapy followed by CRT with fractionated administration of cisplatin in patients with unresectable locally advanced head and neck cancer.2019

    • Author(s)
      Okano S, Enokida T, Onoe T, Ota Y, Motegi A, Zenda S, Akimoto T, Tahara M.
    • Journal Title

      Int J Clin Oncol.

      Volume: 24 Issue: 7 Pages: 789-797

    • DOI

      10.1007/s10147-019-01418-w

    • Data Source
      KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-16K10412
  • [Journal Article] Impact of EGFR Mutation and ALK Translocation on Recurrence Pattern After Definitive Chemoradiotherapy for Inoperable Stage III Non-squamous Non-small-cell Lung Cancer.2019

    • Author(s)
      Nakamura M, Kageyama SI, Niho S, Okumura M, Hojo H, Motegi A, Nakamura N, Zenda S, Yoh K, Goto K, Akimoto T.
    • Journal Title

      Clin Lung Cancer.

      Volume: printing Issue: 3 Pages: e256-e264

    • DOI

      10.1016/j.cllc.2019.02.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10411, KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-16K10412
  • [Journal Article] Impact of Proton Beam Irradiation of an Anatomic Subsegment of the Liver for Hepatocellular Carcinoma2019

    • Author(s)
      Hojo Hidehiro、Raturi Vijay、Nakamura Naoki、Arahira Satoko、Akita Tsunemichi、Mitsunaga Shuichi、Nakamura Masaki、Motegi Atsushi、Kageyama Shun-ichiro、Zenda Sadamoto、Okumura Masayuki、Ikeda Masafumi、Akimoto Tetsuo
    • Journal Title

      Practical Radiation Oncology

      Volume: S1879-8500 Issue: 4 Pages: 30276-0

    • DOI

      10.1016/j.prro.2019.09.012

    • Data Source
      KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-16K10412
  • [Journal Article] Hypofractionated proton beam therapy for centrally located lung cancer.2019

    • Author(s)
      Nakamura N, Hotta K, Zenda S, Baba H, Kito S, Akita T, Motegi A, Hojo H, Nakamura M, Parshuram RV, Okumura M, Akimoto T.
    • Journal Title

      J Med Imaging Radiat Oncol.

      Volume: 63 Issue: 4 Pages: 552-556

    • DOI

      10.1111/1754-9485.12901

    • Data Source
      KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-16K10412
  • [Journal Article] Effect of 5-fluorouracil on cellular response to proton beam in esophageal cancer cell lines according to the position of spread-out Bragg peak.2019

    • Author(s)
      Hojo H, Dohmae T, Hotta K, Kageyama SI, Baba H, Kohno R, Motegi A, Tsuchihara K, Akimoto T.
    • Journal Title

      Acta Oncol

      Volume: 58(4) Issue: 4 Pages: 475-482

    • DOI

      10.1080/0284186x.2018.1555373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10412, KAKENHI-PROJECT-16K10411, KAKENHI-PROJECT-19K08190
  • [Journal Article] Frequency and predictors of detecting early locoregional recurrence/disease progression of oral squamous cell carcinoma with high-risk factors on imaging tests before postoperative adjuvant radiotherapy.2019

    • Author(s)
      Kibe Y, Nakamura N, Kuno H, Hiyama T, Hayashi R, Zenda S, Motegi A, Hojo H, Nakamura M, Ariji T, Oyoshi H, Akimoto T.
    • Journal Title

      Int J Clin Oncol.

      Volume: 24 Issue: 10 Pages: 1182-1189

    • DOI

      10.1007/s10147-019-01479-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-18K15573, KAKENHI-PROJECT-16K10412
  • [Journal Article] The 5-year outcomes of moderately hypofractionated radiotherapy (66 Gy in 22 fractions, 3 fractions per week) for localized prostate cancer: a retrospective study.2018

    • Author(s)
      Yaichiro Hashimoto, Atsushi Motegi, Tetsuo Akimoto, Norio Mitsuhashi, Junpei Iizuka, Kazunari Tanabe, Yuka Ishii, Sawa Kono, Sachiko Izumi, and Kumiko Karasawa
    • Journal Title

      Int J Clin Oncol

      Volume: 23(1) Issue: 1 Pages: 165-172

    • DOI

      10.1007/s10147-017-1175-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Journal Article] Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients.2018

    • Author(s)
      Kageyama SI, Nihei K, Karasawa K, Sawada T, Koizumi F, Yamaguchi S, Kato S, Hojo H, Motegi A, Tsuchihara K, Akimoto T.
    • Journal Title

      Oncotarget.

      Volume: 9(27) Pages: 19368-19378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10412
  • [Journal Article] Correction: Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients.2018

    • Author(s)
      Kageyama SI, Nihei K, Karasawa K, Sawada T, Koizumi F, Yamaguchi S, Kato S, Hojo H, Motegi A, Tsuchihara K, Akimoto T.
    • Journal Title

      Oncotarget

      Volume: 9(34) Issue: 34 Pages: 23844-23844

    • DOI

      10.18632/oncotarget.25378

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10412, KAKENHI-PROJECT-18K08798
  • [Journal Article] Usefulness of hybrid deformable image registration algorithms in prostate radiation therapy2018

    • Author(s)
      Motegi Kana、Tachibana Hidenobu、Motegi Atsushi、Hotta Kenji、Baba Hiromi、Akimoto Tetsuo
    • Journal Title

      Journal of Applied Clinical Medical Physics

      Volume: 20 Issue: 1 Pages: 229-236

    • DOI

      10.1002/acm2.12515

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09078, KAKENHI-PROJECT-18K15572, KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-16K10412
  • [Journal Article] Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients.2018

    • Author(s)
      Kageyama S, Nihei K, Karasawa K,, Sawada T, Koizumi F, Yamaguchi S, Kato S, Hojo H, Motegi A, Tsuchihara K, Akimoto T.
    • Journal Title

      Oncotarget

      Volume: 10;9(27) Issue: 27 Pages: 19368-19378

    • DOI

      10.18632/oncotarget.25053

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10411, KAKENHI-PROJECT-16K19856, KAKENHI-PROJECT-16K10412, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K11029
  • [Journal Article] Proton beam therapy for olfactory neuroblastoma.2017

    • Author(s)
      Naoki Nakamura, Sadamoto Zenda, Makoto Tahara, Susumu Okano, Ryuichi Hayashi, Hidehiro Hojo, Kenji Hotta, Satoe Kito, Atsushi Motegi, Satoko Arahira, Hidenobu Tachibana, and Tetsuo Akimoto
    • Journal Title

      Radiother Oncol

      Volume: 122(3) Issue: 3 Pages: 368-372

    • DOI

      10.1016/j.radonc.2016.12.020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10411, KAKENHI-PROJECT-16K10412
  • [Journal Article] Long-term Clinical Results of Concurrent Chemoradiotherapy for Patients with Cervical Esophageal Squamous Cell Carcinoma.2017

    • Author(s)
      Atsuhiro Kumabe, Sadatomo Zenda, Atsushi Motegi, Masakatsu Onozawa, Naoki Nakamura, Takashi Kojima, Hiroyuki Daiko, Naoyuki Shigematsu, and Tetsuo Akimoto
    • Journal Title

      Anticancer Res

      Volume: 37(9) Issue: 9 Pages: 5039-5044

    • DOI

      10.21873/anticanres.11919

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10411, KAKENHI-PROJECT-15K10008
  • [Journal Article] Difference in the relative biological effectiveness and DNA damage repair processes in response to proton beam therapy according to the positions of the spread out Bragg peak.2017

    • Author(s)
      Hojo H, Dohmae T, Hotta K, Kohno R, Motegi A, Yagishita A, Makinoshima H, Tsuchihara K, Akimoto T
    • Journal Title

      Radiat Oncol

      Volume: 12(1) Pages: 111-116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10412
  • [Journal Article] Difference in the relative biological effectiveness and DNA damage repair processes in response to proton beam therapy according to the positions of the spread out Bragg peak.2017

    • Author(s)
      Hidehiro Hojo, Takeshi Dohmae, Kenji Hotta, Ryosuke Kohno, Atsushi Motegi, Atsushi Yagishita, Hideki Makinoshima, Katsuya Tsuchihara, and Tetsuo Akimoto
    • Journal Title

      10.1186/s13014-017-0849-1

      Volume: 12(1) Issue: 1 Pages: 111-111

    • DOI

      10.1186/s13014-017-0849-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10411, KAKENHI-PROJECT-15K19838
  • [Journal Article] Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced esophageal squamous cell carcinoma2017

    • Author(s)
      Hirano Y, Onozawa M, Hojo H, Motegi A, Zenda S, Hotta K, Moriya S, Tachibana H, Nakamura N, Kojima T, Akimoto T
    • Journal Title

      Radiat Oncol

      Volume: 13(1) Issue: 1 Pages: 474-4481

    • DOI

      10.1186/s13014-018-0966-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10412, KAKENHI-PROJECT-17K09078
  • [Journal Article] Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced non-small cell lung cancer.2016

    • Author(s)
      Wu CT, Motegi A, Motegi K, Hotta K, Kohno R, Tachibana H, Kumagai M, Hojo H, Niho S, Goto K, Akimoto T.
    • Journal Title

      Jon J Clin Oncol

      Volume: - Issue: 11 Pages: 1008-1014

    • DOI

      10.1093/jjco/hyw108

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Journal Article] Impact of prophylactic percutaneous endoscopic gastrostomy tube placement on treatment tolerance in head and neck cancer patients treated with cetuximab plus radiation.2016

    • Author(s)
      Yamazaki T, Enokida T, Wakasugi T, Zenda S, Motegi A, Araria S, Akimoto T, Tahara M.
    • Journal Title

      Jon J Clin Oncol

      Volume: 46 Issue: 9 Pages: 825-31

    • DOI

      10.1093/jjco/hyw079

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Journal Article] Patterns of failure after postoperative intensity-modulated radiotherapy for locally advanced and recurrent head and neck cancer.2016

    • Author(s)
      Ooishi M, Motegi A, Kawashima M, Arahira S, Zenda S, Nakamura N, Ariji T, Tokumaru S, Sakuraba M, Tahara M, Hayashi R, Akimoto T.
    • Journal Title

      Jon J Clin Oncol

      Volume: 46 Issue: 10 Pages: 919-927

    • DOI

      10.1093/jjco/hyw095

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Journal Article] Accelerated radiotherapy for T1-T2 glottic cancer.2014

    • Author(s)
      Atsushi Motegi, Mitsuhiko Kawashima, Satoko Arahira, Sadamoto Zenda, Masamichi Toshima, Masakatsu Onozawa, Ryuichi Hayashi, Tetsuo Akimoto
    • Journal Title

      Head and Neck

      Volume: in press Issue: 4 Pages: 579-84

    • DOI

      10.1002/hed.23641

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24791341, KAKENHI-PROJECT-24591860
  • [Presentation] Phase I dose-escalation trial of proton beam therapy with concurrent full-dose chemotherapy for patients with cStage IB/Ⅱ/2019

    • Author(s)
      Akimoto T, Kojima T, Hojo H, Onozawa M, Okumura M, Nakamura M, Motegi A, Hotta K, Baba H, Zenda S, Fujita T, Nakamura N,
    • Organizer
      61st ASTRO Annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10412
  • [Presentation] 新病期分類(AJCC第8版) に基づく中咽頭癌の放射線治療成績の検討2018

    • Author(s)
      茂木厚、全田貞幹、中村直樹、田原信、林隆一、藤井誠志、秋元哲夫
    • Organizer
      第42回頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Presentation] 頭頸部癌における放射線治療感受性を検討するための低侵襲バイオマーカー(遺伝子解析を含む)の開発2018

    • Author(s)
      茂木 厚
    • Organizer
      日本放射線腫瘍学会 生物部会 制癌シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Presentation] 頭頸部扁平上皮癌における低侵襲バイオマーカーの開発2018

    • Author(s)
      茂木厚
    • Organizer
      日本放射線腫瘍学会 生物部会
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Presentation] 頭頸部癌に対する放射線治療計画CTにおけるMARの有用性の検討2017

    • Author(s)
      茂木厚、良知寿哉、関谷浩太郎、全田貞幹、荒平聡子、中村直樹、小野澤正勝、林隆一、秋元哲夫
    • Organizer
      日本頭頸部癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Presentation] 喉頭癌の放射線治療2016

    • Author(s)
      茂木厚
    • Organizer
      日本医学放射線学会秋季臨床大会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2016-09-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Presentation] 切除可能下咽頭癌に対する根治的放射線治療の長期成績と晩期有害事象2016

    • Author(s)
      茂木厚、荒平聡子、全田貞幹、中村直樹、田原信、林隆一、秋元哲夫
    • Organizer
      日本頭頸部癌学会
    • Place of Presentation
      ソニックシティ (埼玉県さいたま市)
    • Year and Date
      2016-06-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10411
  • [Presentation] 中咽頭癌におけるがん幹細胞マーカー発現とHPV感染の相関の研究2014

    • Author(s)
      茂木厚、藤井誠志、林隆一、秋元哲夫
    • Organizer
      第38回日本頭頸部癌学会
    • Place of Presentation
      東京・有明
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] 中咽頭癌に対する強度変調放射線治療の治療成績と有害事象2013

    • Author(s)
      茂木厚、河島光彦、荒平聡子、全田貞幹、林隆一、秋元哲夫
    • Organizer
      第38回日本頭頸部癌学会
    • Place of Presentation
      東京・新宿
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] 中咽頭癌に対する強度変調放射線治療の治療成績と有害事象の評価2013

    • Author(s)
      茂木厚
    • Organizer
      第37回日本頭頸部癌学会
    • Place of Presentation
      東京(京王プラザホテル)
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] 早期声門癌に対する加速分割照射の治療成績及び晩期有害事象の検討2012

    • Author(s)
      茂木厚
    • Organizer
      第25回日本放射線腫瘍学会
    • Place of Presentation
      東京(東京国際フォーラム)
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] 早期声門癌に対する加速分割照射の治療成績及び晩期有害事象の検討2012

    • Author(s)
      茂木厚
    • Organizer
      第50回がん治療学会
    • Place of Presentation
      横浜市(パシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] Impact of the expression of tumor stem cell marker CD44 and p16 expression on radiotherapeutic outcomes of oropharyngeal squamous cell carcinoma

    • Author(s)
      Atsushi Motegi, Satoshi Fujii, Makoto Tahara, Ryuichi Hayashi and Tetsuo Akimoto
    • Organizer
      15th International Congress of Radiation Reserch
    • Place of Presentation
      Kyoto International Conference Center, Kyoto
    • Year and Date
      2015-05-25 – 2015-05-29
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] Acute toxicities and DVH parameters for OARs of proton beam therapy for stage III non-small cell lung cancer

    • Author(s)
      Atsushi Motegi., Satoko Arahira., Masamichi Toshima., Masakatsu Onozawa., Sadamoto Zenda, Yuichiro Ohe., Tetsuo Akimoto.
    • Organizer
      ASTRO’s 56th annual meeting
    • Place of Presentation
      Moscone Center, San Francisco, USA
    • Year and Date
      2014-09-14 – 2014-09-17
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] 頭頸部扁平上皮癌におけるがん幹細胞マーカー発現とHPV感染の相関の研究

    • Author(s)
      茂木厚、藤井誠志、荒平聡子、全田貞幹、林隆一、田原信、秋元哲夫
    • Organizer
      第38回日本頭頸部癌学会
    • Place of Presentation
      東京ファッションタウンビルホール、東京都
    • Year and Date
      2014-06-12 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-24791341
  • [Presentation] 頭頸部扁平上皮癌におけるがん幹細胞マーカー発現とHPV感染の相関の研究

    • Author(s)
      茂木厚、藤井誠志、荒平聡子、全田貞幹、林隆一、田原信、秋元哲夫
    • Organizer
      日本放射線腫瘍学会第27回学術大会
    • Place of Presentation
      パシフィコ横浜、神奈川
    • Year and Date
      2014-12-11 – 2014-12-13
    • Data Source
      KAKENHI-PROJECT-24791341
  • 1.  Akimoto Tetsuo (10261851)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 2.  北條 秀博 (60638774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 3.  Tsuchihara Kazuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  TACHIBANA Hidenobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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