Nakano Manabu 中野学

… Alternative Names

NAKANO Manabu 中野学

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Researcher Number	10436016
Other IDs
Affiliation (Current)	2025: 弘前大学, 保健学研究科, 助教
Affiliation (based on the past Project Information) *help	2024: 弘前大学, 保健学研究科, 助教 2013 – 2022: 弘前大学, 保健学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related Except Principal Investigator Radiation science / Basic Section 63040:Environmental impact assessment-related
Keywords	Principal Investigator 好塩基球 / P2Y6 / 標的指向性ドラッグデリバリー / アレルギー / P2Y6受容体 / アレルギー反応 / 細胞外ヌクレオチド受容体 / cAMP / ENTPD / Gタンパク質共役型受容体 / 細胞外ヌクレオチド … More Except Principal Investigator … More 造血幹細胞 / 組織適合性抗原 / 放射線被ばく / 放射線被ばく医療 / 臍帯血移植 / プラナリア / 野生動物 / 幹細胞影響 / 環境放射線 / 移植・再生医療 / 放射線 / 造血系サイトカイン / 接着性細胞 / 混合臍帯血移植 / 免疫系再構築 / 被ばく医療 Less

Ｐ２Ｙ６受容体シグナル阻害剤内包標的指向性粒子を用いたアレルギー疾患治療法の探求Principal Investigator
- Principal Investigator
  
  中野学
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Hirosaki University
Investigation of allergy treatment by inhibition of extracellular nucleotide receptor signaling in micePrincipal Investigator
- Principal Investigator
  
  Nakano Manabu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Hirosaki University
Low-Dose radiation effects on freshwater planarian (Dugesia japonica), in Fukushima
- Principal Investigator
  
  Ariyoshi Kentaro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63040:Environmental impact assessment-related
- Research Institution
  Fukushima Medical University
Regulatory mechanism by extracellular nucleotide receptors for basophil activationPrincipal Investigator
- Principal Investigator
  
  Nakano Manabu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Hirosaki University
Comprehensive verification on life-saving mechanism of lethal dose radiation exposed individual by mixed umbilical cord blood transplantation
- Principal Investigator
  
  Ito Koichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
Establishment of effective mixed umbilical cord blood transplantation for lethal dose radiation exposure
- Principal Investigator
  
  Ito Koichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University

All 2022 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] UDP/P2Y6 receptor signaling regulates IgE-dependent degranulation in human basophils2017
- Author(s)
  Nakano Manabu、Ito Koichi、Yuno Takeo、Soma Nobuyuki、Aburakawa Syun、Kasai Kosuke、Nakamura Toshiya、Takami Hideki
- Journal Title
  
  Allergol. Int.
  
  Volume: 66 Issue: 4 Pages: 574-580
- DOI
  10.1016/j.alit.2017.02.014
- NAID
  130006179500
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10338
[Journal Article] Mitigative Effects of a Combination of Multiple Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation2016
- Author(s)
  Hirouchi T, Ito K, Nakano M, Monzen S, Yoshino H, Chiba M, Hazawa M, Nakano A, Ishikawa J, Yamaguchi M, Tanaka K, Kashiwakura I
- Journal Title
  
  Curr Pharm Biotechnol.
  
  Volume: 17 Issue: 2 Pages: 190-199
- DOI
  10.2174/1389201016666150826125331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861054, KAKENHI-PROJECT-25461868
[Journal Article] In Vivo Functional Adaptive Immune Responses in Mice Subjected to Allogeneic Umbilical Cord Blood Cell Transplantation2016
- Author(s)
  Hiroshi Maeda, Hideaki Sato, Mika Araya, Kyoko Ito, Ken-ichiro Terui, Eiki Tsushima, Manabu Nakano, Koichi Ito
- Journal Title
  
  The Hirosaki Medical Journal
  
  Volume: 66 Pages: 162-175
- NAID
  130008046379
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461868
[Journal Article] In vivo functional adaptive immune responses in mice subjected to allogeneic umbilical cord blood cell transplantation.2016
- Author(s)
  Hiroshi Maeda, Hideaki Sato, Mika Araya, Kyoko Ito, Ken-ichiro Terui, Eiki Tsushima, Manabu Nakano and Koichi Ito
- Journal Title
  
  The Hirosaki Medical Journal
  
  Volume: 66 Pages: 162-175
- NAID
  130008046379
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K10338
[Journal Article] Elucidation of the mechanism of immunoregulation after double-unit umbilical cord blood transplantation2014
- Author(s)
  Izumi Namba, Yuka Tamoto, Koichi Terashima, Hiroshi Maeda, Manabu Nakano, Kyoko Ito, and Koichi Ito
- Journal Title
  
  The Proceedings of the 5th International Symposium on Radiation Emergency Medicine at Hirosaki University
  
  Volume: 5 Pages: 31-35
- Data Source
  KAKENHI-PROJECT-25461868
[Journal Article] Long-lasting radioprotective effects of a combination of pharmaceutical drugs on the survaival of mice exposed to lethal lonizing radiation2014
- Author(s)
  Masaru Yamaguchi, Tokuhisa Hirouchi, Manabu Nakano, Satoru Monzen, Hironori Yoshino, Mitsuru Chiba, Junya Ishikawa, Ayaka Nishiyama, Sho Murakami, Koichi Ito and Ikuo Kashiwakura
- Journal Title
  
  Radiation Emergency Medicine
  
  Volume: 3 Pages: 50-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Confirmation of the inhibitory effect of P2Y6 receptor antagonist on allergic reaction2022
- Author(s)
  Manabu Nakano
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17417
[Presentation] P2Y6 receptor signal by the UDP stimulation increases cAMP and IP1 in human basophils.2020
- Author(s)
  Manabu Nakano, Hideki Takami, Kyoko Ito, Koichi Ito
- Organizer
  JSA/WAO Joint Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17417
[Presentation] Effect of extracellular nucleotide hydrolysis on IgE-dependent activation of basophils2019
- Author(s)
  Manabu Nakano, Marina Kikuchi, Airi Yoshioka, Misaki Wahachi, Kyoko Ito, Hideki Takami, Koichi Ito
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16135
[Presentation] 好塩基球活性化に対するE-NTPDaseの影響2019
- Author(s)
  中野学, 菊地毬菜, 時田尚文, 伊藤京子, 高見秀樹, 伊藤巧一
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-18K16135
[Presentation] Effect of MRS2578, a P2Y6 receptor inhibitor, on IgE-dependent activation of human basophils2018
- Author(s)
  Manabu Nakano, Marina Kikuchi, Syun Aburakawa, Naofumi Tokita, Kyoko Ito, Hideki Takami, Koichi Ito
- Organizer
  International GPCR symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16135
[Presentation] Allogeneic double-unit umbilical cord blood cell transplantation facilitates hematopoietic recovery in an irradiated host.2016
- Author(s)
  Ken-ichiro Terui, Sena yamakawa, kyoko Ito, Manabu Nakano and koichi Ito.
- Organizer
  3rd Educational Symposium on Radiation and Health by Young Scientists (ESRAH2016)
- Place of Presentation
  北海道大学(北海道札幌市）
- Year and Date
  2016-10-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10338
[Presentation] マウス同種異系臍帯血移植による機能的免疫細胞再構築に関する検証.2016
- Author(s)
  照井　健一郎, 前田　浩志, 佐藤　英明, 伊藤　京子, 中野　学, 伊藤　巧一.
- Organizer
  第100回弘前医学会総会
- Place of Presentation
  ホテルナクアシティー弘前（青森県弘前市）
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-16K10338
[Presentation] Effect of allogeneic source in double-unit umbilical cord blood transplantation.2016
- Author(s)
  Ken-ichiro Terui, Sena Yamakawa, Kyoko Ito, Manabu Nakano and Koichi Ito.
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県那覇市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K10338
[Presentation] Effectiveness of hematopoietic recovery of allogeneic umbilical cord blood transplantation for acute high-dose total X-ray exposure2015
- Author(s)
  Hiroshi Maeda, Ken-ichiro Terui, Manabu Nakano, Kyoko Ito and Koichi Ito.
- Organizer
  2nd Educational Symposium on Radiation and Health by Young Scientists (ESRAH2014)
- Place of Presentation
  ホテルニューキャッスル(青森県弘前市）
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Effectiveness and characteristics of immune reconstruction by double-unit umbilical cord blood transplantation in mice subjected to whole-body X-ray irradiation2015
- Author(s)
  Ken-ichiro Terui, Sena Yamakawa, Fumika Matsuura, Misa Furuta, Kyoko Ito, Hiroshi Maeda, Manabu Nakano, Koichi Ito
- Organizer
  The 44th Annual Meeting of The Japanese Society for Immunology
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Characteristics of the immune recomstitution by mixed umbilical cord blood cell transplantation for lethal-dose radiation exposure2015
- Author(s)
  Ken-ichiro Terui, Hiroshi Maeda, Manabu Nakano, Kyoko Ito and Koichi Ito.
- Organizer
  2nd Educational Symposium on Radiation and Health by Young Scientists (ESRAH2014)
- Place of Presentation
  ホテルニューキャッスル(青森県弘前市）
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Allogeneic umbilical cord blood cell transplantation for the treatment of acute high-dose total body X-ray irradiation in mice2015
- Author(s)
  Hiroshi Maeda, Ken-ichiro Terui, Hikaru Ajima, Kyoko Ito, Manabu Nakano, and Koichi Ito
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Is double unit umbilical cord blood cell transplantation an effective therapeutic strategy for lethal dose radiation exposure?2015
- Author(s)
  Ken-ichiro Terui, Hikaru Ajima, Hiroshi Maeda, Kyoko Ito, Manabu Nakano, and Koichi Ito
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Elucidation of the mechanism of immunoregulation after double-unit umbilical cord blood transplantation2013
- Author(s)
  Izumi Namba, Yuka Tamoto, Koichi Terashima, Hiroshi Maeda, Manabu Nakano, Kyoko Ito, and Koichi Ito
- Organizer
  The 5th International Symposium on Radiation Emergency Medicine in Hirosaki University
- Place of Presentation
  ホテルクラウンパレス青森(青森県青森市）
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Allogeneic umbilical cord blood transplantation for acute high-dose total body X-ray exposure in mice
- Author(s)
  Hiroshi Maeda, Ken-ichiro Terui, Hikaru Ajima, Manabu Nakano, Kyoko Ito, Koichi Ito
- Organizer
  The 1st Educational Symposium of RADIATION and HEALTH by Young Scientists
- Place of Presentation
  ホテルニューキャッスル（青森県弘前市）
- Year and Date
  2014-09-21 – 2014-09-22
- Data Source
  KAKENHI-PROJECT-25461868
[Presentation] Analysis of immune reconstitution by murine allogeneic umbilical cord blood transplantation
- Author(s)
  Hiroshi Maeda, Kyoko Ito, Hideaki Sato, Manabu Nakano, Koichi Ito
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館(京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25461868

1. Ito Koichi (90398579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. Ariyoshi Kentaro (50462750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 三浦富智 (20261456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 葛西宏介 (50400148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田副博文 (60447381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MONZEN Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakano Manabu 中野 学

NAKANO Manabu 中野 学

Research Projects

Research Products

Co-Researchers

Ｐ２Ｙ６受容体シグナル阻害剤内包標的指向性粒子を用いたアレルギー疾患治療法の探求Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of allergy treatment by inhibition of extracellular nucleotide receptor signaling in micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Low-Dose radiation effects on freshwater planarian (Dugesia&#160;japonica), in Fukushima

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanism by extracellular nucleotide receptors for basophil activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive verification on life-saving mechanism of lethal dose radiation exposed individual by mixed umbilical cord blood transplantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of effective mixed umbilical cord blood transplantation for lethal dose radiation exposure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] UDP/P2Y6 receptor signaling regulates IgE-dependent degranulation in human basophils2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Mitigative Effects of a Combination of Multiple Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In Vivo Functional Adaptive Immune Responses in Mice Subjected to Allogeneic Umbilical Cord Blood Cell Transplantation2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] In vivo functional adaptive immune responses in mice subjected to allogeneic umbilical cord blood cell transplantation.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Elucidation of the mechanism of immunoregulation after double-unit umbilical cord blood transplantation2014

Author(s)

Journal Title

Data Source

[Journal Article] Long-lasting radioprotective effects of a combination of pharmaceutical drugs on the survaival of mice exposed to lethal lonizing radiation2014

Author(s)

Journal Title

Data Source

[Presentation] Confirmation of the inhibitory effect of P2Y6 receptor antagonist on allergic reaction2022

Author(s)

Organizer

Data Source

[Presentation] P2Y6 receptor signal by the UDP stimulation increases cAMP and IP1 in human basophils.2020

Author(s)

Organizer

Data Source

Nakano Manabu 中野学

NAKANO Manabu 中野学

Low-Dose radiation effects on freshwater planarian (Dugesia japonica), in Fukushima