Kubo Shuji 久保秀司

… Alternative Names

Researcher Number	10441320
Other IDs
Affiliation (Current)	2022: 兵庫医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2010 – 2021: 兵庫医科大学, 医学部, 准教授 2015: 兵庫医科大学, 医学部, 教授 2013: 兵庫医科大学, 准教授 2009: 兵庫医科大学, 医学部, 助教 2007: 兵庫医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Experimental pathology / General surgery / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery / Clinical oncology / Urology / Environmental physiology (including Physical medicine and Nutritional physiology) / Neurology / General surgery … More
Keywords	Principal Investigator 癌 / ウイルス療法 / がんウイルス療法 / 増殖型レトロウイルスベクター / 悪性中皮腫 / 遺伝子治療 / 自殺遺伝子療法 / 癌遺伝子治療 / 腫瘍溶解アデノウイルス / 骨肉腫 … More Except Principal Investigator ミトコンドリア / γδT細胞 / 中皮腫 / 前立腺癌 / 遺伝子治療 / PET / [^<18>F]FDG / [^<18>F]FHBG / TRP / 中枢性呼吸調節 / グリア細胞 / 二酸化炭素 / 延髄 / 中枢化学受容器 / 呼吸調節 / カルシウム応答 / ATP / 筋強直性ジストロフィー / 中枢神経症状 / スプライシング異常 / MBNL1/2 / 国際情報交換 / 米国、フロリダ / 米国、フロリダ大学 / 国際情報交流 / 癌ワクチン / 腫瘍溶解ウイルス / Oncolytic virus / Immunogenic cell death / 腫瘍溶解アデノウイルス / IL-18 / 免疫チェックポイント阻害薬 / 抗CTLA4抗体 / 抗PD-L1抗体 / NK細胞 / Treg / CD8陽性T細胞 / 抗CTLA4 抗体 / 抗PD-１抗体 / 抗PD-L１抗体 / IDO阻害剤 / オートファジー / がん免疫治療 / CTLA4 / PD-L1 / CD８陽性T細胞 / CD8陽性細胞 / 抗腫瘍効果 / ヘルパーNK細胞 / γδＴ細胞 / γδTリンパ球 / サイトカイン / 胃がん / 腹膜播種 / 微小環境 / グルココルチコイド / 抗がん剤 / ストレス / シスプラチン / 薬剤耐性 / 抗がん剤耐性 / Srcファミリーキナーゼ / アポトーシス / Fyn / Lyn / スフェロイド / ダサチニブ / 悪性中皮腫 / 3p領域 / BAP1遺伝子 / クロマチンリモデリング / 転写制御 / HDAC阻害剤 / ゲノム多型 / 易罹患性 / クロマチン構造 / ゲノム不安定性 / ヒストンアセチル化 / 3p21 / PBRM1遺伝子 / MLPA法 / 腸管機能不全 / CD56brightCD11c positive / 侵襲 / CD56brightCD11c+細胞 / SP-D / 壊死性腸炎 / サーファクタント蛋白D / 消化管 / サーファクタント / 膵臓 / 肝臓 / toll-like receptor / 胎児 / 腸管粘膜防御機構 / IL-36 / 歯肉上皮細胞 / 歯周病 / ＩＬ－３６ / 家族性大腸腺腫症 / マイクロRNA / バイオマーカー / デスモイド / 脳梗塞 / 幹細胞 / 神経再生 / 移植 Less

播種性癌に対する革新的な自殺遺伝子ウイルス療法の開発Principal Investigator
- Principal Investigator
  
  久保秀司
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hyogo College of Medicine
幹細胞をキャリアとして利用した骨肉腫肺転移に対するウイルス療法の開発Principal Investigator
- Principal Investigator
  
  久保秀司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Hyogo College of Medicine
Development of cell transplantation therapy using human injury/ischemia-induced neural stem/progenitor cells
- Principal Investigator
  
  Nakagomi Takayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Hyogo College of Medicine
Development of retroviral replicating vector-mediated suicide gene therapy for malignant mesotheliomaPrincipal Investigator
- Principal Investigator
  
  KUBO Shuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hyogo College of Medicine
Development of molecular marker and novel therapy for FAP
- Principal Investigator
  
  Yamano Tomoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hyogo College of Medicine
Potential role of IL-1 family cytokines in periodontal diseases
- Principal Investigator
  
  Ohyama Hideki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Osaka Medical College
  Hyogo College of Medicine
Development of oncolytic adenovirus as a new therapeutic agent for treating disseminated cancersPrincipal Investigator
- Principal Investigator
  
  Kubo Shuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hyogo College of Medicine
Intestinal surfactant protein in the intestinal failure of low birth weight children
- Principal Investigator
  
  Okuyama Hiroomi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Osaka University
  Hyogo College of Medicine
Effect of combination of IL-18 and immune checkpoint inhibitors on peritoneal dissemination of tumor cells
- Principal Investigator
  
  Okamura Haruki
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Hyogo College of Medicine
The role of glucocorticoid in mitochondria-dependent resistance to anticancer therapy
- Principal Investigator
  
  KASAHARA EMIKO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Osaka City University
Role of Src-family kinase in the progression of malignant tumor cells and its clinical implication
- Principal Investigator
  
  FUJIMORI Yoshihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Hyogo College of Medicine
Deletion of the 3p region in malignant mesothelioma cells derived from Japanese patients
- Principal Investigator
  
  HASHIMOTO-TAMAOKI Tomoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hyogo College of Medicine
Analysis of Functional Bowel Disorder and Development of Vew Treatments
- Principal Investigator
  
  MAEYAMA YOSHIHIRO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo College of Medicine
The elucidation of central chemosensitive respiratory regulation by TRP channels expressed in glial cell.
- Principal Investigator
  
  HIRATA Yutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Hyogo College of Medicine
Molecular pathogenesis of myotonic dystrophy in the central nervous system
- Principal Investigator
  
  TAKASHI Kimura
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hyogo College of Medicine
Development of a novel cancer vaccine using chemokine CCL21 and oncolytic adenovirus
- Principal Investigator
  
  YAMANO Tomoki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hyogo College of Medicine
Development of oncolytic adenovirus as a new therapeutic agent for treating human malignant mesotheliomaPrincipal Investigator
- Principal Investigator
  
  KUBO Shuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hyogo College of Medicine
The assessment using Positron Emission Tomography in conditionally replicating adenovirus therapy.
- Principal Investigator
  
  GOTOH Akinobu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Hyogo College of Medicine

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] A patient‐derived xenograft and a cell line derived from it form a useful preclinical model for small bowel adenocarcinoma2020
- Author(s)
  Tomoki Yamano, Shuji Kubo, Naohiro Tomita
- Journal Title
  
  Cancer Medicine
  
  Volume: 00 Pages: 3337-3343
- DOI
  10.1002/cam4.2986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10658, KAKENHI-PROJECT-19K22697
[Journal Article] Efficient tumor transduction and antitumor efficacy in experimental human osteosarcoma using retroviral replicating vectors2019
- Author(s)
  Kubo S, Takagi-Kimura M, Kasahara N
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 26 Pages: 41-47
- DOI
  10.1038/s41417-018-0037-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10484, KAKENHI-PROJECT-18H00470
[Journal Article] Splicing modulator FR901464 is a potential agent for colorectal cancer in combination therapy2019
- Author(s)
  Yamano Tomoki、Kubo Shuji、Yano Aya、Kominato Tomoko、Tanaka Shino、Ikeda Masataka、Tomita Naohiro
- Journal Title
  
  Oncotarget
  
  Volume: 10 Pages: 352-367
- DOI
  10.18632/oncotarget.26564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10484
[Journal Article] Dual-vector prodrug activator gene therapy using retroviral replicating vectors2019
- Author(s)
  Kubo S, Takagi-Kimura M, Tagawa M, Kasahara N
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: Epub ahead of print
- DOI
  10.1038/s41417-018-0051-0
- Description
  Epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10484, KAKENHI-PROJECT-18H00470
[Journal Article] Brain vascular pericytes following ischemia have multipotentialstem cell activity to differentiate into neural and vascular lineage cells.2015
- Author(s)
  Nakagomi T, Kubo S, Nakano-Doi A, Sakuma R, Lu S, Narita A, Kawahara M, Taguchi A, Matsuyama T.
- Journal Title
  
  Stem Cells
  
  Volume: ー Issue: 6 Pages: 1962-1974
- DOI
  10.1002/stem.1977
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501353, KAKENHI-PROJECT-24650173, KAKENHI-PROJECT-15H00593, KAKENHI-PROJECT-15K09329
[Journal Article] Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.2015
- Author(s)
  Matsushita K, Kitamura K, Rahmutulla B, Tanaka N, Ishige T, Satoh M, Hoshino T, Miyagi S, Mori T, Itoga S, Shimada H, Tomonaga T, Kito M, Nakajima-Takagi Y, Kubo S, Nakaseko C, Hatano M, Miki T, Matsuo M, Fukuyo M, Kaneda A, Iwama A, Nomura F.
- Journal Title
  
  Oncotarget
  
  Volume: 10 Pages: 5102-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501353
[Journal Article] Combinatorial anti-angiogenic gene therapy in a human malignant mesothelioma model2015
- Author(s)
  Kubo S, Takagi-Kimura M, Kasahara N
- Journal Title
  
  Oncology Report
  
  Volume: 34 Pages: 633-638
- DOI
  10.3892/or.2015.4058
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460484
[Journal Article] Oncolytic virotherapy for osteosarcoma using midkine promoter-regulated adenoviruses.2014
- Author(s)
  Takagi-Kimura M, Yamano T, Tagawa M, Kubo S
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 21 Pages: 126-32
- DOI
  10.1038/cgt.2014.7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24501353, KAKENHI-PROJECT-25460484
[Journal Article] Oncolytic virotherapy for osteosarcoma using midkine promoter-regulated adenoviruses2014
- Author(s)
  Takagi-Kimura Misato, Yamano Tomoki, Tagawa Masatoshi, Kubo Shuji
- Journal Title
  
  Cancer gene therapy
  
  Volume: 21(3) Pages: 126-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591973
[Journal Article] Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/ cyclinE and Ku86/ XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.2014
- Author(s)
  Rahmutulla B, Matsushita K, Satoh M, Seimiya M, Tsuchida S, Kubo S, Shimada H, Ohtsuka M, Miyazaki M, Nomura F.
- Journal Title
  
  Oncotarget
  
  Volume: 15 Pages: 2404-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501353
[Journal Article] Enhanced antitumor efficacy of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma.2013
- Author(s)
  Takagi-Kimura, M., Yamano, T., Tamamoto, A., Okamura, N., Okamura, H., Hashimoto-Tamaoki, T., Tagawa, M., Kasahara, N. and Kubo, S.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Pages: 1433-1439
- DOI
  10.1111/cas.12267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-25460484
[Journal Article] Enhanced antitumor efficacy of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma2013
- Author(s)
  Takagi-Kimura Misato, Yamano Tomoki, Tamamoto Atsuko, Okamura Nobutaka, Okamura Haruki, Hashimoto-Tamaoki Tomoko, Tagawa Masatoshi, Kasahara Noriyuki, Kubo Shuji
- Journal Title
  
  Cancer science
  
  Volume: 104(11) Pages: 1433-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591973
[Journal Article] Highly efficient tumor transduction and antitumor efficacy in experimental human malignant mesothelioma using replicating gibbon ape leukemia virus.2013
- Author(s)
  Kubo S, Takagi-Kimura M, Logg CR, Kasahara N.
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 20 Pages: 671-7
- DOI
  10.1038/cgt.2013.67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460484
[Journal Article] Deficiency of Fyn protein is prerequisite for apoptosis induced by Src family kinase inhibitors in human mesothelioma cells.2012
- Author(s)
  Eguchi R, Kubo S, Takeda H, Ogawa H, et al.(8人中6番)
- Journal Title
  
  Carcinogenesis
  
  Volume: 33 Pages: 969-75
- DOI
  10.1093/carcin/bgs109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591252, KAKENHI-PROJECT-23591167, KAKENHI-PROJECT-24501361
[Journal Article] Hybrid vectors as Trojan horses; adventure with adenovirus for successful gene therapy.2012
- Author(s)
  Kubo S
- Journal Title
  
  Acta Med Hyogo
  
  Volume: 37 Pages: 95-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590370
[Journal Article] Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma2011
- Author(s)
  Kawasaki Y, Tamamoto A, Takagi-Kimura M, Maeyama Y, Yamaoka N, Terada N, Okamura H, Kasahara N, Kubo S.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 18 Pages: 571-578
- DOI
  10.1038/cgt.2011.25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590370
[Journal Article] Adenovirus-retrovirus hybrid vectors achieve highly enhanced tumor transduction and antitumor efficacy in vivo.2011
- Author(s)
  Kubo S, Haga K, Tamamoto A, Palmer DJ, Ng P, Okamura H, Kasahara N.
- Journal Title
  
  Mol Ther
  
  Volume: 19 Pages: 76-82
- DOI
  10.1038/mt.2010.182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590370
[Journal Article] Adenovirus-retrovirus hybrid vectors achieve highly enhanced tumor transduction and antitumor efficacy in vivo2011
- Author(s)
  Kubo S申請代表者が筆頭著者及び責任著者
- Journal Title
  
  Mol Ther
  
  Volume: 19 Pages: 485-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590370
[Journal Article] Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus.2010
- Author(s)
  Kubo S, Kawasaki Y, Yamaoka N
- Journal Title
  
  Tagawa M, Kasahara N, Terada N, Okamura H. J Gene Med.
  
  Volume: 12 Pages: 681-92
- DOI
  10.1002/jgm.1486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590370
[Journal Article] Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus2010
- Author(s)
  Kubo S申請代表者が筆頭著者及び責任著者
- Journal Title
  
  Journal of Gene Medicine
  
  Volume: VOL.10 Pages: 681-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590370
[Journal Article] Adenovirus vector production using low-multiplicity infection of 293 cells2009
- Author(s)
  Yamada K, Morishita N, Katsuda T, Kubo S, Gotoh A, Yamaji H
- Journal Title
  
  Cytotechnology 59巻
  
  Pages: 153-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390420
[Presentation] Usefulness of suicide gene therapy for ovarian cancer using retroviral replicating vector2020
- Author(s)
  Shuji Kubo, Tomoki Yamano, Kosei Hasegawa
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] 骨肉腫に対する増殖型レトロウイルスベクターを用いた細胞死誘導型がんウイルス療法2020
- Author(s)
  久保秀司、磯田莉沙、藤野宏晃、園田絵観子
- Organizer
  第123回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Suicide Gene Therapy Using Retroviral Replicating Vectors in an Experimental Model of Human Gastric Cancer2020
- Author(s)
  Shuji Kubo, Hiroaki Fujino, Ayane Kawabe, Noriyuki Kasahara, Emiko Sonoda, and Toru Takarada
- Organizer
  日本人類遺伝学会第65回大会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Potential Utility Of Retroviral Replicating Vector-Mediated Prodrug Activator Gene Therapy For Human Ovarian Cancer2020
- Author(s)
  Shuji Kubo, Lisa Isoda, Hiroaki Fujino, Emiko Sonoda, Kosei Hasegawa, Noriyuki Kasahara, Toru Takarada
- Organizer
  American Society of Gene & Cell Therapy 23rd annual meeting
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Mesenchymal Stem Cells As Tumor-homing Cellular Carriers For Retroviral Replicating Vectors2019
- Author(s)
  Hiroaki Fujino, Lisa Isoda, Emiko Sonoda, Noriyuki Kasahara, Shuji Kubo
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Human mesenchymal stem cells as tumor-homing cellular carriers of retroviral replicating vectors for cancer gene therapy2019
- Author(s)
  Shuji Kubo, Hiroaki Fujino, Noriyuki Kasahara
- Organizer
  第27回欧州遺伝子細胞治療学会(ESGCT 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Development of human mesenchymal stem cells as tumor-homing cellular carriers for retroviral replicating vectors2019
- Author(s)
  Shuji Kubo, Hiroaki Fujino, Takao Morinaga, Masatoshi Tagawa, Noriyuki Kasahara
- Organizer
  第25回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Mesenchymal Stem Cells as Carriers of Retroviral Replicating Vectors for Cancer Gene Therapy2019
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Lisa Isoda, Hiroaki Fujino, Noriyuki Kasahara
- Organizer
  第22回米国遺伝子治療学会議(ASGCT 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Mesenchymal stem cells as cellular vehicles to deliver retroviral replicating vectors for cancer gene therapy2019
- Author(s)
  Shuji Kubo, Takao Morinaga, Tomoki Yamano
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Mesenchymal Stem Cells as Carriers of Retroviral Replicating Vectors for Cancer Gene Therapy2019
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Lisa Isoda, Hiroaki Fujino, and Noriyuki Kasahara
- Organizer
  日本人類遺伝学会第64回大会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] 間葉系幹細胞を運搬体として用いた増殖型レトロウイルスベクターの新規デリバリー法の開発2019
- Author(s)
  久保秀司、藤野宏晃、笠原典之
- Organizer
  第26回日本遺伝子診療学会大会
- Data Source
  KAKENHI-PROJECT-19K22697
[Presentation] Retroviral replicating vector-mediated suicide gene therapy for solid tumors2018
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Lisa Isoda, Noriyuki Kasahara
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Human Mesenchymal Stem Cells as Cellular Vehicles to Deliver Retroviral Replicating Vectors for Cancer Gene Therapy2018
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura and Noriyuki Kasahara
- Organizer
  第24回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] 幹細胞をキャリアとして利用した増殖型レトロウイルスによる癌自殺遺伝子療法の開発2018
- Author(s)
  久保秀司、木村（高木）美智、笠原典之
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Mesenchymal stem cells as carriers of retroviral replicating vectors for cancer gene therapy2018
- Author(s)
  Misato Takagi-Kimura, Lisa Isoda, Noriyuki Kasahara, Shuji Kubo
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Potential Utility of Mesenchymal Stem Cells as Retroviral Replicating Vector Delivery Vehicles for Gene Therapy of Cancer2018
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura and Noriyuki Kasahara
- Organizer
  21th Annual Meeting of the American Society of Gene & Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] 骨肉腫に対する細胞死誘導型がんウイルス療法2018
- Author(s)
  久保秀司、木村（高木）美智、笠原典之
- Organizer
  第25回日本遺伝子診療学会大会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] uman Mesenchymal Stem Cells as Cellular Vehicles to Deliver Retroviral Replicating Vectors for Cancer Gene Therapy2018
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Masatoshi Tagawa, Noriyuki Kasahara
- Organizer
  Annual Meeting of the European Society of Gene and Cell Therapy 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Mesenchymal Stem Cells Can Be Used As Carriers Of Retroviral Replicating Vectors For Cancer Gene Therapy2018
- Author(s)
  久保秀司、木村（高木）美智、山野智基、田川雅敏、笠原典之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Retroviral replicating vector-mediated prodrug activator gene therapy for osteosarcoma2017
- Author(s)
  Kubo S, Takagi-Kimura M, Kasahara N
- Organizer
  第23回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Retroviral replicating vector-mediated suicide gene therapy for osteosarcoma2017
- Author(s)
  久保秀司、木村（高木）美智、山野智基、笠原典之
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] 増殖型レトロウイルスを用いた自殺遺伝子療法の開発2017
- Author(s)
  久保秀司
- Organizer
  2017年度生命科学系学会合同年次大会（第40回日本分子生物学会年会）
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Retroviral replicating vector-mediated prodrug activator gene therapy in an experimental model of human osteosarcoma2017
- Author(s)
  Kubo S, Takagi-Kimura M, Kasahara N
- Organizer
  Annual Meeting of the European Society of Gene and Cell Therapy 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] 増殖型レトロウイルスを用いた細胞死誘導型癌ウイルス療法の開発2017
- Author(s)
  久保秀司
- Organizer
  金沢大学薬学シンポジウム2017
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Suicide gene therapy using retroviral replicating vectors in an experimental model of human osteosarcoma2017
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Noriyuki Kasahara
- Organizer
  第62回日本人類遺伝学会第62回大会
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Prodrug activator gene therapy using retroviral replicating vectors in an experimental model of human osteosarcoma2017
- Author(s)
  Kubo S, Takagi-Kimura M, Kasahara N
- Organizer
  20th Annual Meeting of the American Society of Gene & Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Customization of virotherapy with replicating retroviral replicating vectors on the basis of cellular receptor expression profiles.2016
- Author(s)
  Kubo S, Mawatari-Furukawa Y, Sakagami R, Kasahara N
- Organizer
  第22回日本遺伝子細胞治療学会学術総会
- Place of Presentation
  慈恵医科大学（東京都港区）
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Customization of virotherapy with retroviral replicating vectors on the basis of cellular receptor expression profiles.2016
- Author(s)
  Kubo S, Mawatari-Furukawa Y, Kasahara N
- Organizer
  Annual Meeting of the European Society of Gene and Cell Therapy 2016
- Place of Presentation
  Florence, Italy
- Year and Date
  2016-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Combinatorial anti-angiogenic gene therapy in a human malignant mesothelioma model.2016
- Author(s)
  Kubo S, Takagi-Kimura M, Logg CR, Hermann K, Kasahara N
- Organizer
  19th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington DC, USA
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] A tailor-made virotherapy with retroviral replicating vectors on the basis of the receptor expression2016
- Author(s)
  Kubo S, Yamano T, Kasahara N
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] 増殖型レトロウイルスを用いた個別化ウイルス療法の可能性2016
- Author(s)
  久保秀司、山野智基、笠原典之
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K10484
[Presentation] Dual-vector prodrug activator gene therapy using two different retroviral replicating vectors2015
- Author(s)
  Kubo S, Takagi-Kimura M, Logg CR, Hermann K, Kasahara N
- Organizer
  The European Society of Gene and Cell Therapy
- Place of Presentation
  ヘルシンキ（フィンランド）
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Dual-vector prodrug activator gene therapy using retroviral replicating vectors derived from amphotropic murine leukemia virus and gibbon ape leukemia virus2015
- Author(s)
  Kubo S, Takagi-Kimura M, Logg CR, Hermann K, Kasahara N
- Organizer
  The American Society of Gene & Cell Therapy
- Place of Presentation
  ニューオーリンズ（米国）
- Year and Date
  2015-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] ケモカインCCL21と腫瘍溶解アデノウイルスを用いた新しい癌ワクチン療法の開発2014
- Author(s)
  山野智基、久保秀司、冨田尚裕、他
- Organizer
  日本癌治療学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591973
[Presentation] ケモカインCCL21と腫瘍溶解アデノウイルスを用いた新しい癌ワクチン療法の開発2014
- Author(s)
  山野智基,久保秀司,矢野綾,松原長秀,山本英幸,岡村春樹,冨田尚裕
- Organizer
  日本癌治療学会
- Place of Presentation
  横浜
- Year and Date
  2014-08-29
- Data Source
  KAKENHI-PROJECT-23591973
[Presentation] 二重制御型アデノウイルスを用いた骨肉腫に対する腫瘍溶解療法の開発2013
- Author(s)
  久保秀司、木村美智、玉本敦子、山野智基、玉置知子、笠原典之、田川雅敏
- Organizer
  (一般)日本人類遺伝学会第58回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23591973
[Presentation] Biological roles of deletion of PBRM1 and BAP1 in malignant mesotheliomas 悪性中皮腫におけるBAP1 とPBRM1 遺伝子の複合欠失と癌化における役割2013
- Author(s)
  Yoshie Yoshikawa, Ayuko Sato, Tohru Tsujimura, Shuji Kubo, Mitsuru Emi Seiki　Hasegawa, Takashi Nakano, Tomoko Hashimoto-Tamaoki. 吉川良恵、佐藤鮎子、辻村亨、久保秀司、江見充、長谷川誠紀、中野孝司、玉置（橋本）知子
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590715
[Presentation] Dual targeted adenovirus for oncolytic virotherapy in experimental human osteosarcoma.(General Lecture)2013
- Author(s)
  Kubo Shuji, Takagi-Kimura Misato, Yamano Tomoki, Yoshikawa Yoshie,Emi Mitsuru, Tagawa Masatoshi, Kasahara Noriyuki, Hashimoto-Tamaoki Tomoko
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23591973
[Presentation] Enhanced transduction of human malignant mesothelioma cells by midkine promoter-driven oncolytic adenovirus with Ad35 fiber modification2012
- Author(s)
  Kubo S
- Organizer
  第18回日本遺伝子治療学会学術集会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Enhanced transduction of humanmalignant mesothelioma cells by midkine promoter-driven oncolytic adenoviruswith Ad35 fiber modification.2012
- Author(s)
  久保秀司
- Organizer
  第18回日本遺伝子治療学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] BAP1遺伝子の上皮型悪性中皮腫での高頻度欠失2012
- Author(s)
  吉川良恵，江見充，森永伴法，久保秀司，佐藤鮎子，辻村亨，長谷川誠紀，中野孝司，玉置（橋本）知子
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590715
[Presentation] 筋強直性ジストロフィー症における中枢神経スプライシング異常およびその分子機序の解明2012
- Author(s)
  末永浩一，木村卓，Lee K-Y ,中森雅之，高橋正紀，藤村晴俊，陣内研二，久保秀司，玉置（橋本）知子，Manuel A, Maurice S,芳川浩男
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591258
[Presentation] 悪性中皮腫に対する二重制御型（転写制御+ファイバー置換）腫瘍溶解アデノウイルスの開発2012
- Author(s)
  久保秀司
- Organizer
  第19回日本遺伝子診療学会大会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Hybrid vector as Trojan horses; Adventure with adenovirus for long-team gene expression trough permanent chromosomal integration.2012
- Author(s)
  久保秀司
- Organizer
  第18回日本遺伝子治療学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 悪性中皮腫に対する二重制御型(転写制御+ファイバー置換)腫瘍溶解アデノウイルスの開発.2012
- Author(s)
  久保秀司
- Organizer
  第19回日本遺伝子診療学会大会
- Place of Presentation
  千葉市
- Year and Date
  2012-07-27
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 悪性中皮腫に対する二重制御型腫瘍溶解アデノウイルスの開発.2012
- Author(s)
  久保秀司
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Replication-competent retrovirus vector-mediated suicide gene therapy in experimental models of human malignant mesothelioma.2012
- Author(s)
  久保秀司
- Organizer
  11th International Conference of the International Mesothelioma Interest Group
- Place of Presentation
  Boston(米国)
- Year and Date
  2012-09-12
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Replication -competent retrovirus vector-mediated suicide gene therapy in experimental models of human malignant mesothelioma.2012
- Author(s)
  Kubo S
- Organizer
  11th International Conference of the International Mesothelioma Interest Group
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Midkine promoter-driven oncolytic adenovirus with Ad35 fiber modefication achieves enhanced transduction of human malignant mesothelioma cells in vitro and in vivo.2012
- Author(s)
  Kubo　S
- Organizer
  15th Annual Meeting of the American Socisety of Gene Therapy
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Midkine promoter-driven oncolytic adenovirus with Ad35 fiber modefication achieves enhanced transduction of human malignant mesothelioma cells in vitro and in vivo.2012
- Author(s)
  久保秀司
- Organizer
  15th Annual Meeting of the American Socisety of Gene Therapy
- Place of Presentation
  Philadelphia(米国)
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Adventure of genethera pywith adenovirus.2012
- Author(s)
  久保秀司
- Organizer
  第14回外科分子細胞治療研究会(招待講演)
- Place of Presentation
  千葉市
- Year and Date
  2012-04-12
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Adventure of gene therapy with adenovirus2012
- Author(s)
  久保秀司
- Organizer
  第14回外科分子細胞治療研究会
- Place of Presentation
  千葉市
- Invited
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 悪性中皮腫に対する二重制御型腫瘍溶解アデノウイルスの開発2012
- Author(s)
  久保秀司
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 筋強直性ジストロフィー症における中枢神経スプラシング異常およびその分子機序の解明2012
- Author(s)
  末永浩一、木村卓、Kuang-Yung Lee、中森雅之、高橋正紀、藤村晴俊、陣内研二、久保秀司、玉置(橋本)知子、Manuel Ares Jr.、Maurice S. Swanson、芳川浩男
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-23591258
[Presentation] 悪性中皮腫におけるBAP1遺伝子欠失のMLPA法での詳細解析2012
- Author(s)
  江見充，佐藤秀則，吉川良恵，森永伴法，佐藤鮎子，久保秀司，辻村亨，長谷川誠紀，中野孝司，玉置（橋本）知子
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590715
[Presentation] 筋強直性ジストロフィー症におけるスプライシング異常およびその分子機序の解明2011
- Author(s)
  末永浩一，木村卓，Lee K，中森雅之，高橋正紀，松村剛，藤村晴俊，陣内研二，久保秀司，玉置（橋本）知子，Ares M, Swanson MS, 芳川浩男
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591258
[Presentation] Midkine promoter-regulatedoncolytic adenovirus achieved complete and sustained tumor regression of human malignant mesothelioma xenografts inathymic mice.2011
- Author(s)
  久保秀司
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Midkine promoter-regulated oncolytic adenovirus achieved complete and sustained tumor regression of human malignant mesothelioma xenografts in athymic mice2011
- Author(s)
  久保秀司
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Complete and sustained tumor regression of human malignant mesothelioma xenografts in athymic nude mice following local injection of midkine promoter-regulated oncolytic adenovirus.2011
- Author(s)
  久保秀司
- Organizer
  14th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  シアトル(米国)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma2011
- Author(s)
  久保秀司
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  九州大学医学部百年講堂(福岡市)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 増殖型ウイルスを用いた悪性中皮腫に対する自殺遺伝子療法2011
- Author(s)
  久保秀司
- Organizer
  日本人類遺伝学会第56回大会
- Place of Presentation
  幕張メッセ(千葉市)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] In vivo fluorescence imaging of malignant mesothelioma in mice for the evaluation of cancer gene therapy using replication-competent virus2011
- Author(s)
  久保秀司
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] In vivo fluorescence imaging ofmalignant mesothelioma in mice for the evaluation of cancer gene therapy usingreplication-competent virus.2011
- Author(s)
  久保秀司
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Complete and sustained tumor regression of human malignant mesothelioma xenografts in athymic nude mice following local injection of midkine promoter-regulated oncolytic adenovirus2011
- Author(s)
  久保秀司
- Organizer
  14^<th> Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Washington State Convention & Trade Center(米国シアトル)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 筋強直性ジストロフィー症における中枢神経スプラシング異常およびその分子機序の解明2011
- Author(s)
  末永浩一、木村卓、Kuang-Yung Lee、中森雅之、高橋正紀、松村到、藤村晴俊、陣内研二、久保秀司、玉置(橋本)知子、Manuel Ares Jr., Maurice S. Swanson,芳川浩男
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23591258
[Presentation] 増殖型ウイルスを用いた悪性中皮腫に対する自殺遺伝子療法.2011
- Author(s)
  久保秀司
- Organizer
  日本人類遺伝学会第56回大会
- Place of Presentation
  千葉市
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma.2011
- Author(s)
  久保秀司
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡市
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Complete and sustained tumor regression of human malignant mesothelioma xenografts in athymic mice following local injection of midkine promoter-regulated oncolytic adenovirus.2010
- Author(s)
  久保秀司
- Organizer
  The 10th International Conference of the International Mesothelioma Interest Group
- Place of Presentation
  京都市
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Complete and sustained tumor regression of human malignant mesothelioma xenografts in athymic mice following local injection of midkine promoter-regulated oncolytic adenovirus2010
- Author(s)
  久保秀司
- Organizer
  The 10th International Conference of the International Mesothelioma Interest Group
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 制限増殖型アデノウイルスを用いた悪性中皮腫に対する腫瘍溶解療法2010
- Author(s)
  久保秀司
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Midkine promoter-driven oncolytic adenovinis achieves effective targeting of human malignant mesothelioma cells in vitro and in vivo2010
- Author(s)
  久保秀司
- Organizer
  第16回日本遺伝子治療学会
- Place of Presentation
  栃木県総合文化センター(栃木市)
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 制限増殖型アデノウイルスを用いた悪性中皮腫に対する腫瘍溶解療法2010
- Author(s)
  久保秀司
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Establishment of in vivo fluorescence imaging models for human malignant mesothelioma in mice2010
- Author(s)
  久保秀司
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Midkine promoter-drivenoncolytic adenovirus achieves effective targeting of human malignant mesothelioma cells in vitro and in vivo.2010
- Author(s)
  久保秀司
- Organizer
  第16回日本遺伝子治療学会
- Place of Presentation
  栃木市
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] Establishment of in vivofluorescence imaging models for human malignant mesothelioma in mice.2010
- Author(s)
  久保秀司
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22590370
[Presentation] 骨肉腫に対する二重制御型アデノウイルスを用いた腫瘍溶解療法
- Author(s)
  久保秀司、木村美智、山野智基、田川雅敏
- Organizer
  第３７回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] ミッドカインプロモーター制御型アデノウイルスを用いた骨肉腫に対する腫瘍溶解療法
- Author(s)
  久保秀司、木村美智、山野智基、玉置知子、田川雅敏
- Organizer
  人類遺伝学会第５９回大会
- Place of Presentation
  東京
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Development of Dual Targeted Oncolytic Adenovirus for Human Malignant Mesothelioma.
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Atsuko Tamamoto, Tomoko Hashimoto-Tamaoki
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Salt Lake City, USA
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Rare germline variants of transcription regulator genes in malignent mesothelioma
- Author(s)
  吉川良恵、大搗泰一郎、久保秀司、佐藤鮎子、辻村亨、江. 見充、中野孝司、玉置（橋本）知子
- Organizer
  第73回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590715
[Presentation] Highly efficient tumor transduction and antitumor efficacy in experimental human malignant mesothelioma using replicating gibbon ape leukemia virus
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Christopher R Logg and Noriyuki Kasahara
- Organizer
  17th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] ヘルペスウイルスチミジンキナーゼを用いた癌自殺遺伝子治療を最適化する腫瘍融解ウイルスの開発
- Author(s)
  久保秀司
- Organizer
  第39回日本応用酵素協会研究発表会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Prodrug activator gene therapy using replicating gibbon ape leukemia virus in an experimental model of human malignant mesothelioma
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Christopher R Logg and Noriyuki Kasahara
- Organizer
  第２０回日本遺伝子治療学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] 増殖型ウイルスを用いた悪性中皮腫に対する自殺遺伝子療法
- Author(s)
  久保秀司，木村（高木）美智，Logg Christopher R，笠原典之
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Enhanced transduction and antitumor efficiency of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura and Masatoshi Tagawa
- Organizer
  12th International Conference of the International Mesothelioma Interest Group
- Place of Presentation
  Cape Town (South Africa)
- Year and Date
  2014-10-21 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] ケモカインCCL21と腫瘍溶解アデノウイルスを用いた新しい癌ワクチン療法の開発
- Author(s)
  山野智基、久保秀司、矢野綾、山本　英幸、岡村春樹、冨田尚裕
- Organizer
  第52回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Suicide gene therapy by replicating gibbon ape leukemia virus in an experimental model of human malignant mesothelioma
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Christopher R Logg and Noriyuki Kasahara
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Comparative evaluation of suicide gene therapy using retroviral peplicating vectors in an experimental model of human malignant mesothelioma.
- Author(s)
  Kubo Shuji, Kasahara Noriyuki.
- Organizer
  iMig 2014
- Place of Presentation
  Cape town (South Africa)
- Year and Date
  2014-10-21 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24501353
[Presentation] Dual targeted adenovirus for oncolytic virotherapy in experimental human osteosarcoma
- Author(s)
  久保秀司、木村（高木）美智、山野智基、吉川良恵、江見充、田川雅敏、笠原典之、玉置（橋本）知子
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] 二重制御型アデノウイルスを用いた骨肉腫に対する腫瘍溶解療法の開発
- Author(s)
  久保秀司、木村美智、玉本敦子、山野智基、玉置知子、笠原典之、田川雅敏
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Enhanced transduction and antitumor efficiency of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Masatoshi Tagawa
- Organizer
  11th International Adenovirus Meeting
- Place of Presentation
  San Diego (USA)
- Year and Date
  2014-07-16 – 2014-07-20
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] Midkine Promoter-Driven Oncolytic Adenovirus with Ad35 Fiber Modification Achieves Enhanced Transduction of Human Osteosarcoma Cells.
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Atsuko Tamamoto, Nobutaka Okamura, Masatoshi Tagawa, Noriyuki Kasahara, Haruki Okamura and Tomoko Hashimoto-Tamaoki
- Organizer
  第１９回日本遺伝子治療学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-25460484
[Presentation] 遺伝子治療研究の最近の進歩
- Author(s)
  久保秀司
- Organizer
  第42回臨床細胞分子遺伝研究会･第14回関西出生前診療研究会学術集会合同集会
- Place of Presentation
  西宮
- Invited
- Data Source
  KAKENHI-PROJECT-25460484

1. YAMANO Tomoki (00599318)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
2. OKAMURA Haruki (60111043)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. OHYAMA Hideki (90280685)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. Nakagomi Takayuki (80434950)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. SENDA Michio (00216558)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TOMINAGA Hideyuki (00393348)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TOMITA Naohiro (00252643)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KIKUCHI Shojiro (70381960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MAEYAMA YOSHIHIRO (80614031)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. GOTOH Akinobu (70283885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. TERAO Shuuji (10457103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TERADA Nobuyuki (50150339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. HIRATA Yutaka (10441247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OKU Yoshitaka (20252512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKASHI Kimura (20441264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. YOSHIKAWA Hiroo (90273680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. KASAHARA EMIKO (30468269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. SEKIYAMA Atsuo (30403702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. FUJIMORI Yoshihiro (20229058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. EGUTI Ryoji (00461088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. HASHIMOTO-TAMAOKI Tomoko (10172868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YOSHIKAWA Yoshie (10566673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. MORINAGA Tomonori (10351818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. EMI Mitsuru (90221118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
25. SHIMA Hiroki (90104257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ISHIKAWA Takehiko (70280849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Okuyama Hiroomi (30252670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. Saka Ryuta (00459190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Sasaki Takashi (20388573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. Yanagihara Itaru (60314415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 笹子三津留 (40143490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 田中義正 (90280700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 中野孝司 (10155781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
34. 野瀬聡子 (90467564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 中正恵二 (00217712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 山根木康嗣 (00434944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 山田直子 (10319858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 小越菜保子 (60509115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 高木俊範 (00452152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 松山知弘 (10219529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 吉村紳一 (40240353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 麸谷博之 (30248140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. LI Wen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. MA Zhifeng

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. SEKI Hatsuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. Yosif El-Darawish

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. TABATA Chiharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 田川雅敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 田口明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 松山知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 富田尚裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
52. 島知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
53. 小川啓恭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubo Shuji 久保 秀司

KUBO Shuji 久保 秀司

久保 秀司 クボ シュウジ

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播種性癌に対する革新的な自殺遺伝子ウイルス療法の開発Principal Investigator

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幹細胞をキャリアとして利用した骨肉腫肺転移に対するウイルス療法の開発Principal Investigator

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Development of retroviral replicating vector-mediated suicide gene therapy for malignant mesotheliomaPrincipal Investigator

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Development of oncolytic adenovirus as a new therapeutic agent for treating disseminated cancersPrincipal Investigator

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Kubo Shuji 久保秀司

KUBO Shuji 久保秀司

久保秀司クボシュウジ