TAKEGAHARA Noriko 竹ヶ原宜子

Researcher Number	10444522
Affiliation (based on the past Project Information) *help	2015 – 2016: 大阪大学, 免疫学フロンティア研究センター, 特任准教授 2010: Osaka University, 助教 2007 – 2009: Osaka University, 微生物病研究所, 助教
Review Section/Research Field	Principal Investigator Cell biology / General medical chemistry / Biological Sciences / Biological Sciences
Keywords	Principal Investigator 破骨細胞 / podosome / 時空間制御 / small G protein / 細胞内シグナル伝達 / セマフォリン / 膜タンパク分子 / 細胞融合 / 細胞骨格・運動 / ヘルパーT細胞 … More / 骨代謝疾患 / 自己免疫疾患 / 骨免疫学 / 免疫学 / 細胞内・細胞間情報伝達 / 接着分子 / ストローマ細胞 Less

免疫の『場』を形成する新たなストローマ細胞としての破骨細胞の機能解明Principal Investigator
- Principal Investigator
  
  竹ヶ原宜子
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
多核巨細胞の形成を担う細胞融合メカニズムの解明Principal Investigator
- Principal Investigator
  
  竹ヶ原宜子
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
破骨細胞分化メカニズムの時空間的解明Principal Investigator
- Principal Investigator
  
  竹ヶ原宜子
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
セマフォリンをターゲットとした自己免疫疾患制御の試みPrincipal Investigator
- Principal Investigator
  
  竹ヶ原宜子
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
細胞融合を担う分子メカニズムの時空間制御機構の解明Principal Investigator
- Principal Investigator
  
  竹ヶ原宜子
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Investigation of molecular mechanisms of semaphorin signailingPrincipal Investigator
- Principal Investigator
  
  TAKEGAHARA Noriko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University

All 2016 2015 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Involvement of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts.2016
- Author(s)
  Takegahara N, Kim H, Mizuno H, Sakaue-Sawano A, Miyawaki A, Tomura M, Kanagawa O, Ishii M, Choi Y.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 291 Issue: 7 Pages: 3439-3454
- DOI
  10.1074/jbc.m115.677427
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01156, KAKENHI-PLANNED-24111007, KAKENHI-PROJECT-15K07047, KAKENHI-PROJECT-25440095
[Journal Article] Involvement of semaphorins and their receptors in neurological diseases2010
- Author(s)
  Takegahara N, Kumanogoh A.
- Journal Title
  
  Clinical and Experimental Neuroimmunology 1
  
  Pages: 33-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770206
[Journal Article] Involvement of semaphorins and their receptors in neurological diseases2010
- Author(s)
  Takegahara N, Kumanogoh A.
- Journal Title
  
  Clinical and Experimental Neuroimmunology 1
  
  Pages: 33-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060016
[Journal Article] Involvement of semaphorins and their receptors in neurological diseases2010
- Author(s)
  Takegahara N, Kumanogoh A.
- Journal Title
  
  Clinical and Experimental Neuroimmunology 1
  
  Pages: 33-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200066
[Journal Article] Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.2008
- Author(s)
  Toyofuku T, Yoshida J, Sugimoto T, Yamamoto M, Makino N, Takamatsu H, Takegahara N, (以下5 名)
- Journal Title
  
  Dev Biol. 321
  
  Pages: 251-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770174
[Journal Article] Involvement of Sema4A in the progression of experimental autoimmune myocarditis.2008
- Author(s)
  Makino N, Toyofuku T, Takegahara N, (以下8名)
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 3935-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770174
[Journal Article] Plexin-A4 negatively regulates T lymphocyte responses.2008
- Author(s)
  Yamamoto M, Suzuki K, Okuno T, Ogata T, Takegahara N, (以下8 名)
- Journal Title
  
  Int Immunol. 20
  
  Pages: 413-20
- NAID
  10021240042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770174
[Journal Article] Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.2007
- Author(s)
  Suzuki K, Okuno T, Yamamoto M, Pasterkamp RJ, Takegahara N, (以下7 名)
- Journal Title
  
  Nature. 446
  
  Pages: 680-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770174
[Presentation] 細胞質分裂の失敗　破骨細胞の多核化を担う新たなメカニズム2016
- Author(s)
  竹ヶ原宜子
- Organizer
  日本リウマチ学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市西区みなとみらい1丁目1‐1）
- Year and Date
  2016-04-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01156
[Presentation] 破骨細胞の融合メカニズム2016
- Author(s)
  竹ヶ原宜子
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区中之島5丁目3‐51）
- Year and Date
  2016-07-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01156
[Presentation] 細胞質分裂の失敗　破骨細胞の多核化を担う新たなメカニズム2016
- Author(s)
  竹ヶ原宜子
- Organizer
  日本リウマチ学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市西区みなとみらい1丁目1‐1）
- Year and Date
  2016-04-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K07047
[Presentation] 破骨細胞の融合メカニズム2016
- Author(s)
  竹ヶ原宜子
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区中之島5丁目3‐51）
- Year and Date
  2016-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K07047
[Presentation] RANKLによって誘導される細胞質分裂の失敗は破骨細胞の倍数性増大に寄与する2015
- Author(s)
  竹ヶ原宜子
- Organizer
  日本骨代謝学会
- Place of Presentation
  京王プラザホテル（東京都新宿区西新宿2丁目2‐1）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PUBLICLY-15H01156
[Presentation] RANKL-induced incomplete cytokinesis constitutes osteoclast polyploidization in addition to cell fusion2015
- Author(s)
  Noriko Takegahara
- Organizer
  Australian New Zealand Bone and Mineral Society Annual Scientific Meeting 2015
- Place of Presentation
  Hotel Grand Chancellor Hobart (Tasmania, Australia)
- Year and Date
  2015-11-01
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01156
[Presentation] RANKLによって誘導される細胞質分裂の失敗は破骨細胞の倍数性増大に寄与する2015
- Author(s)
  竹ヶ原宜子
- Organizer
  日本骨代謝学会
- Place of Presentation
  京王プラザホテル（東京都新宿区西新宿2丁目2‐1）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K07047
[Presentation] RANKLによって誘導される細胞質分裂の失敗は破骨細胞の倍数性増大に寄与する2015
- Author(s)
  竹ヶ原宜子、Hyunsoo Kim、Yongwon Choi
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市中央区中町港島6丁目）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K07047
[Presentation] RANKL-induced incomplete cytokinesis constitutes osteoclast polyploidization in addition to cell fusion2015
- Author(s)
  Noriko Takegahara
- Organizer
  Australian New Zealand Bone and Mineral Society Annual Scientific Meeting 2015
- Place of Presentation
  Hotel Grand Chancellor Hobart, Tasmania, (Australia)
- Year and Date
  2015-11-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07047
[Presentation] RANKLによって誘導される細胞質分裂の失敗は破骨細胞の倍数性増大に寄与する2015
- Author(s)
  竹ヶ原宜子、Hyunsoo Kim、Yongwon Choi
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市中央区中町港島6丁目）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01156
[Presentation] Involvement of semaphorin-plexin signaling in regulation of osteo clastoaenesis2009
- Author(s)
  Takegahara N
- Organizer
  The 26^<th> Naito Conference on Osteobiology
- Place of Presentation
  兵庫県淡路島
- Data Source
  KAKENHI-PROJECT-21770206
[Presentation] Involvement of semaphorin-plexin signaling in regulation of osteo clastogenesis2009
- Author(s)
  Takegahara N
- Organizer
  The 26^<th> Naito Conference on Osteobiology
- Place of Presentation
  兵庫県淡路島
- Data Source
  KAKENHI-PROJECT-20060016
[Presentation] Involvement of semaphorin-plexin signaling in regulation of osteo clastogenesis2009
- Author(s)
  Takegahara N
- Organizer
  The 26^<th> Naito Conference on Osteobiology
- Place of Presentation
  兵庫県淡路島
- Data Source
  KAKENHI-PROJECT-20200066
[Presentation] Involvement of a guanine nucleotide exchange factor, FARP2, in osteoclastogenesis2008
- Author(s)
  Takegahara Noriko
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20200066
[Presentation] Involvement of a guanine nucleotide exchange factor, FARP2, inosteoclastogenesis2008
- Author(s)
  Takegahara Noriko
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19770174
[Presentation] Involvement of a guanine nucleotide exchange factor, FARP2, in osteoclastogenesis2008
- Author(s)
  Takegahara Noriko
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19770174

1. 熊ノ郷淳 (10294125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 熊郷淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKEGAHARA Noriko 竹ヶ原 宜子

Research Projects

Research Products

Co-Researchers

免疫の『場』を形成する新たなストローマ細胞としての破骨細胞の機能解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多核巨細胞の形成を担う細胞融合メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

破骨細胞分化メカニズムの時空間的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

セマフォリンをターゲットとした自己免疫疾患制御の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞融合を担う分子メカニズムの時空間制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of molecular mechanisms of semaphorin signailingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Involvement of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of semaphorins and their receptors in neurological diseases2010

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of semaphorins and their receptors in neurological diseases2010

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of semaphorins and their receptors in neurological diseases2010

Author(s)

Journal Title

Data Source

[Journal Article] Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.2008

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of Sema4A in the progression of experimental autoimmune myocarditis.2008

Author(s)

Journal Title

Data Source

[Journal Article] Plexin-A4 negatively regulates T lymphocyte responses.2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.2007

Author(s)

Journal Title

Data Source

[Presentation] 細胞質分裂の失敗 破骨細胞の多核化を担う新たなメカニズム2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

TAKEGAHARA Noriko 竹ヶ原宜子

[Presentation] 細胞質分裂の失敗　破骨細胞の多核化を担う新たなメカニズム2016

[Presentation] 細胞質分裂の失敗　破骨細胞の多核化を担う新たなメカニズム2016