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MAI Wei  麦 威

ORCIDConnect your ORCID iD *help
Researcher Number 10447659
External Links
Affiliation (based on the past Project Information) *help 2009: 金沢大, がん研究所, 研究員
2007 – 2008: Kanazawa University, がん研究所, 研究員
Review Section/Research Field
Principal Investigator
Digestive surgery
Keywords
Principal Investigator
治療 / GSK3β / 分子標的 / 消化器がん
  • Research Projects

    (2 results)
  • Research Products

    (40 results)
  •  消化器がんのGSK3β阻害効果に基づく新しいがん治療法と分子標的治療薬の開発Principal Investigator

    • Principal Investigator
      麦 威
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University
  •  Molecular basis for developing a strategy of cancer treatment targeting aberrant GSK3βPrincipal Investigator

    • Principal Investigator
      MAI Wei
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

All 2009 2008 2007 2006

All Journal Article Presentation

  • [Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2009

    • Author(s)
      Miyashita K, Kawakami K, Mai W, et.al.
    • Journal Title

      Clinical Cancer Research 15

      Pages: 887-897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma.2009

    • Author(s)
      Miyashita K, Kawakami K, Nakada M, Mai W, Shakoori A, Fujisawa H, Hayashi Y, Hamada J, Minamoto T.
    • Journal Title

      Clin Cancer Res 15 (3)

      Pages: 887-897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodents.2007

    • Author(s)
      Shakoori A, Mai W (equal contribution), et. al.
    • Journal Title

      Cancer Science 98

      Pages: 1388-93

    • NAID

      10019998582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Journal Article] Glycogen synthase kinase 3β:消化器がんの新しい治療標的2007

    • Author(s)
      源 利成, 麦 威, ほか.
    • Journal Title

      消化器科 44

      Pages: 468-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodents.2007

    • Author(s)
      Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K, Minamoto T.
    • Journal Title

      Cancer Sci 98(9)

      Pages: 1388-93

    • NAID

      10019998582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Journal Article] Detection of active fraction of GSK3β in cancer cells by nonradioisotopic in vitro kinase assay.2006

    • Author(s)
      Mai W, et. al.
    • Journal Title

      Oncology(註:2007年7月に掲載) 71

      Pages: 297-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Journal Article] Detection of active fraction of GSK3β in cancer cells by nonradioisotopic in vitro kinase assay.2006

    • Author(s)
      Mai W, Miyashita K, Shakoori A, Zhang B, Yu ZW, Takahashi Y, Motoo Y, Kawakami K, Minamoto T.
    • Journal Title

      Oncology 71(3-4)(published in July 23, 2007)

      Pages: 297-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Inhibition of GSK3β activity attenuates proliferation of human colon cancer cells in rodents.2008

    • Author(s)
      Minamoto T, Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA, U.S.A.
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 膵癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008

    • Author(s)
      島崎猛夫, 石垣靖人, 夏啓勝, 中谷直喜, 友杉直久, 田中卓二, 麦威, 川上和之, 源利成, 元雄良治
    • Organizer
      第19回日本消化器癌発生学会総会 : ミニシンポジウム (4) 化学療法
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 膵癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008

    • Author(s)
      島崎猛夫, 麦威, ほか
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 膵癌における新しい分子標的としてのGSK3βとその関連遺伝子群の解析2008

    • Author(s)
      島崎猛夫, 石垣靖人, 中谷直喜, 中島日出夫, 友杉直久, 田中卓二, 麦威, 川上和之, 源利成, 元雄良治
    • Organizer
      第6回日本臨床腫瘍学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer.2008

    • Author(s)
      Kawakami K, Jin MJ, Saito K, Miyashita K, Mai W, Watanabe Go, Minamoto T
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA, U.S.A.
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer : basic analysis for future clinical trial.2008

    • Author(s)
      Shimasaki T, Ishigaki,Y Nakaya N, Nakajima H, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発2008

    • Author(s)
      川上和之, 金明姫, 斉藤健一郎, 麦威, 宮下勝吉, 源利成
    • Organizer
      第19回日本消化器癌発生学会総会 : ミニシンポジウム (8) 癌の診断と治療
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発2008

    • Author(s)
      川上和之, 麦威, ほか
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Inhibition of GSK3I3β activity attenuates proliferation of human colon cancer cells in rodents2008

    • Author(s)
      Minamoto T, Shakoori A, Mai W, et.al.
    • Organizer
      Annual Meeting 2008 of the American Association fox Cancer Research
    • Place of Presentation
      米国サンディエゴ
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Distinct pathologic property of glycogen synthase kinase 3β (GSK3β) in gastrointestinal, pancreatic and liver cancers, 胃がん, 大腸がん, 膵がんと肝がんに共通するglycogen synthase kinase 3β (GSK3β)の病的作用2008

    • Author(s)
      Mai W, Miyashita K, Shakoori A, Shimasaki T, Yasumoto K, Yoshiharu Motoo, Kawakami K, Minamoto T.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Detection of active fraction of GSK3β in cancer cells by non-radioisotopic in vitro kinase assay.2008

    • Author(s)
      Mai W, Shakoori A, Miyashita K, Zhang B, Motoo Y, Kawakami K, Takahashi Y, Minamoto T.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA, U.S.A.
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] GSK3β阻害によるp53とRb経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾2008

    • Author(s)
      宮下勝吉, 麦威, ほか
    • Organizer
      第67回日本癌学会学術総会第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer2008

    • Author(s)
      Kawakami K, Mai W, et.al.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      米国サンディエゴ
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 胃がん,大腸がん,膵がんと肝がんに共通するglycogen synthase kinase 3β(GSK3β)の病的作用2008

    • Author(s)
      麦威, ほか
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Detection of active fraction of GSK3β in cancer cells by non-radioisotopic in vitro kinase assay2008

    • Author(s)
      Mai W, et.al.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      米国サンディエゴ
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] GSK3β inhibition sensitizes glioblastoma cells to chemotherapy and radiation by modulating p53 and Rb pathways, GSK3β阻害によるp53とRb経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾2008

    • Author(s)
      Miyashita K, Nakada M, Fujisawa H, Mai W, Kawakami K, Jun-ichiro Hamada, Minamoto T.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer : basic analysis for future clinical trial2008

    • Author(s)
      島崎猛夫, 麦威, ほか
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer resulting in altered gene expression profiles.2007

    • Author(s)
      Shimasaki T, Mai W, et. al.
    • Organizer
      The Second Meeting of Asian-Oceanic Pancreatic Association (AOPA)
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-18
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Inhibition of glycogen synthase kinase 3β (GSK3β) attenuates proliferation of human colon cancer cells in rodents.2007

    • Author(s)
      Minamoto T, Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 膵癌に対する塩酸ゲムシタビンとGSK3β阻害剤併用の抗腫瘍効果とその分子機構.2007

    • Author(s)
      島崎猛夫, 麦 威, ほか.
    • Organizer
      第18回日本消化器がん発生学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 消化器がんの新しい治療標的GSK3βの発現,活性,機能解析.2007

    • Author(s)
      川上和之, 麦 威, ほか.
    • Organizer
      第18回日本消化器がん発生学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Inhibition of glycogen synthase kinase 3β (GSK3β) in glioblastoma attenuates tumor cells' viability and induces apoptosis depending on p53.2007

    • Author(s)
      Miyashita K, Mai W, et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with colorectal cancer (大腸癌における予後因子としてのLINE-1メチル化)2007

    • Author(s)
      Kawakami K, Mai W, Miyashita K, Watanabe G, Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with colorectal cancer.2007

    • Author(s)
      Kawakami K, Mai W, et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitors against human pancreas cancer: GSK3β as a new therapeutic target.2007

    • Author(s)
      Shimasaki T, Mai W, et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitors against human pancreas cancer : GSK3β as a new therapeutic target.2007

    • Author(s)
      Shimasaki T, Ishigaki Y, Nakajima H, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
    • Organizer
      第66回日本癌学会学術総会 English Workshops 14 Kinase Inhibitors,
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitor against human pancreas cancer: GSK3β as a new therapeutic molecular target.2007

    • Author(s)
      Shimasaki T, Mai W, et. al.
    • Organizer
      Annual Meeting of American Pancreatic Association
    • Place of Presentation
      アメリカ合衆国 シカゴ
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitor against human pancreas cancer : GSK3β as a new therapeutic molecular target.2007

    • Author(s)
      Shimasaki T, Ishigaki Y, Zhao X, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
    • Organizer
      Annual Meeting of American Pancreatic Association
    • Place of Presentation
      Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 消化器がんの新しい治療標的GSK3βの発現, 活性, 機能解析2007

    • Author(s)
      川上和之, 麦威, 島崎猛夫, 宮下勝吉, 安本和生, 高橋豊, 大井章史, 元雄良治, 源利成
    • Organizer
      第18回日本消化器がん発生学会総会 W2. 消化器癌分子標的治療の基礎と臨床
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] 膵癌に対する塩酸ゲムシタビンとGSK3β阻害剤併用の抗腫瘍効果とその分子機構2007

    • Author(s)
      島崎猛夫, 石垣靖人, 趙 霞, 友杉直久, 田中卓二, 麦 威, 川上和之, 源 利成, 元雄良治
    • Organizer
      第18回日本消化器がん発生学会総会 W3. 消化器癌化学療法の基礎と臨床
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Ihhibition of glycogen synthase kinase 3β (GSK3β) attenuates proliferation of human colon cancer cells in rodents.2007

    • Author(s)
      Minamoto T, Mai W, et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Inhibition of glycogen synthase kinase 3β (GSK3β) in glioblastoma attenuates tumor cells' viability and induces apoptosis depending on p53 (GSK3β阻害による神経膠芽腫細胞の生存・増殖抑制とp53関連アポトーシス誘 導機構の解明)2007

    • Author(s)
      Miyashita K, Mai W, FujisawaH, Hamada J-I, Kawakami K, Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938
  • [Presentation] Expression, deregulated activity and pathologic role of GSK3β in gastrointestinal, pancreas and liver cancers.2007

    • Author(s)
      Mai W, Miyashita K, Shakoori A, Shimasaki T, Motoo Y, Kawakami K, Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790938

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