KITAMURA Akiko 北村明子

Researcher Number	10448318
Affiliation (based on the past Project Information) *help	2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2011 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教 2012: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 2009 – 2010: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 助教 … More 2008: The University of Tokushima, 大学院・ヘルスパイオサイエンス研究部, 助教 2008: The University of Tokushima, ヘルスバイオサイエンス研究部, 助教 2007: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 非常勤講師 Less
Review Section/Research Field	Principal Investigator Pediatrics
Keywords	Principal Investigator 自己炎症症候群 / 全身性エリテマトーデス / キャプチャー・リシークエンス / ポジショナルクローニング / 自己接合体マッピング / 多因子遺伝性腎疾患 / 多因子疾患

NLRC4インフラマソームの機能異常による自己炎症病態の分子基盤解明Principal Investigator
- Principal Investigator
  
  北村明子
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokushima
Clarifying the molecular mechanism of autoinflammation caused by dysfunction of immunoproteasome complexesPrincipal Investigator
- Principal Investigator
  
  KITAMURA Akiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokushima
Identification of a critical gene involved in the pathogenesis of systemic lupus erythematosus by linkage analysis and exome resequencingPrincipal Investigator
- Principal Investigator
  
  KITAMURA Akiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokushima
Genome-wide search for a candidate gene in systemic lupus erythematosusPrincipal Investigator
- Principal Investigator
  
  KITAMURA Akiko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokushima
Identification of causative genes for hereditary renal diseases based on inbreeding coefficientsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Akiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokushima

All 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] 先天性・乳児ネフローゼ症候群2008
- Author(s)
  北村明子
- Total Pages
  10
- Publisher
  腎と透析
- Data Source
  KAKENHI-PROJECT-19790725
[Journal Article] Manipulation of CD98 resolves type 1 diabetes in nonobese diabetic mice2012
- Author(s)
  ian G, Arimochi H, Kitamura A, Nishida J, Li S, Kishihara K, Maekawa Y, Yasutomo K
- Journal Title
  
  J Immunol
  
  Volume: 188 Issue: 5 Pages: 2227-34
- DOI
  10.4049/jimmunol.1102586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679005, KAKENHI-PROJECT-21590536, KAKENHI-PROJECT-23791179
[Journal Article] Notch2 regulates the development of marginal zone B cells through Fos2012
- Author(s)
  Iwahashi S, Maekawa Y, Nishida J, Ishifune C, Kitamura A, Arimochi H, Kataoko K, Chiba S, Shimada M, Yasutomo K
- Journal Title
  
  iochem Biophys Res Commun
  
  Volume: 418 Issue: 4 Pages: 701-707
- DOI
  10.1016/j.bbrc.2012.01.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679005, KAKENHI-PROJECT-23390324, KAKENHI-PROJECT-23500958, KAKENHI-PROJECT-23791179, KAKENHI-PROJECT-24890146
[Journal Article] Notch signaling regulates the development of a novel type of Thy1-expressing dendritic cell in the thymus.2011
- Author(s)
  Ishifune C, Maekawa Y, Nishida J, Kitamura A, Tanigaki K, Yagita H, Yasutomo K.
- Journal Title
  
  Eur J Immunol 41
  
  Pages: 1309-1320
- Data Source
  KAKENHI-PROJECT-21790991
[Journal Article] A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans2011
- Author(s)
  Kitamura A, Maekawa Y, Uehara H, Izumi K, Kawachi I, Nishizawa M, Toyoshima Y, Takahashi H, Standley DM, Tanaka K, Hamazaki J, Murata S, Obara K, Toyoshima I, Yasutomo K.
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Issue: 10 Pages: 4150-4160
- DOI
  10.1172/jci58414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679005, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-21570169, KAKENHI-PROJECT-21590536, KAKENHI-PROJECT-23591236, KAKENHI-PROJECT-23657083, KAKENHI-PROJECT-23791179
[Journal Article] Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor.2010
- Author(s)
  Alam MS, Maekawa Y, Kitamura A, Tanigaki K, Yoshimoto T, Kishihara K, Yasutomo K.
- Journal Title
  
  Proc Natl Acad Sci USA 107
  
  Pages: 5943-5948
- Data Source
  KAKENHI-PROJECT-21790991
[Journal Article] Notch2 signaling is required for potent anti-tumor immunity in vivo.2010
- Author(s)
  Sugimoto K, Maekawa Y, Kitamura A, Nishida J, Koyanagi A, Yagita H, Kojima H, Chiba S, Shimada M, Yasutomo K.
- Journal Title
  
  J Immunol 184
  
  Pages: 4673-4678
- Data Source
  KAKENHI-PROJECT-21790991
[Journal Article] ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis.2010
- Author(s)
  Urushihara M, Takamatsu M, Shimizu M, Kondo S, Kinoshita Y, Suga K, Kitamura A, Matsuura S, Yoshizumi M, Tamaki T, Kawachi H, Kagami S.
- Journal Title
  
  Am J Physiol Renal Physiol 298
- Data Source
  KAKENHI-PROJECT-21790991
[Journal Article] 全身性エリテマトーデスの原因遺伝子2009
- Author(s)
  北村明子、安友康二
- Journal Title
  
  小児内科 41
  
  Pages: 242-245
- Data Source
  KAKENHI-PROJECT-19790725
[Journal Article] Jagged1 suppresses collagen-induced arthritis by indirectly providing a negative signal in CD8+ T cells.2009
- Author(s)
  Kijima M, Iwata A, Maekawa Y, Uehara H, Izumi K, Kitamura A, Yagita H, Chiba S, Shiota H, Yasutomo K.
- Journal Title
  
  J Immunol 182
  
  Pages: 3566-3572
- Data Source
  KAKENHI-PROJECT-21790991
[Journal Article] Predisposition to relapsing nephrotic syndrome by a nephrin mutation that interferes with assembly of functioning microdomains.2009
- Author(s)
  Shono A, Tsukaguchi H, Kitamura A, Hiramoto R, Qin XS, Doi T, Iijima K.
- Journal Title
  
  Hum Mol Genet 18
  
  Pages: 2943-2956
- Data Source
  KAKENHI-PROJECT-21790991
[Journal Article] Steroid-resistant nephrotic syndrome2008
- Author(s)
  KitaMura, A
- Journal Title
  
  Kidney International 74
  
  Pages: 1209-1215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790725
[Journal Article] Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity2008
- Author(s)
  Maekawa, Y, Minato, Y, Ishilune, C, Kurihara, T, Kitamura, A, Kojima, H, Yagita, 11, Sakata-Yanagimoto, Saito, T Taniuchi, I, Chiba, 5, Sone, S & Yasutomo, K:
- Journal Title
  
  Nat Immunol 9
  
  Pages: 1140-1147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790725
[Journal Article] 先天性・乳児ネフローゼ症候群2008
- Author(s)
  北村明子、香美祥二
- Journal Title
  
  腎と透析 64
  
  Pages: 963-972
- Data Source
  KAKENHI-PROJECT-19790725
[Journal Article] ネフローゼ症候群責任遺伝子の探索2008
- Author(s)
  塚口裕康、北村明子
- Journal Title
  
  腎と透析 64
  
  Pages: 887-901
- Data Source
  KAKENHI-PROJECT-19790725
[Journal Article] A familial childhood-onset relapsing nephrotic syndrome.2007
- Author(s)
  Kitamura, A, Tsukaguchi, H, Hiramoto, R, Shono, A, Doi, T, Kagami, S & Iijima, K:
- Journal Title
  
  Kidney Int 71
  
  Pages: 946-951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790725
[Journal Article] ネフローゼの治療最前線一先天性・乳児ネフローゼ症候群の治療2007
- Author(s)
  北村明子、香美祥ニ
- Journal Title
  
  小児科 48
  
  Pages: 137-148
- Data Source
  KAKENHI-PROJECT-19790725
[Presentation] Candidate genetic variations in an autosomal-dominant selective immunodeficiency syndrome2013
- Author(s)
  Akiko Kitamura, Koji Yasutomo
- Organizer
  International Symposium on Genome Science "Expanding Frontiers of Genome Science"
- Place of Presentation
  The University of Tokyo, Ito International Research Center, (東京都)
- Data Source
  KAKENHI-PROJECT-23791179
[Presentation] 反復性発熱・結節性紅斑・脂肪萎縮を特徴とする新規自己炎症性症候群の原因遺伝子同定2011
- Author(s)
  北村明子
- Organizer
  日本小児科学会
- Place of Presentation
  グランドプリンスホテル高輪（東京都）
- Data Source
  KAKENHI-PROJECT-23791179
[Presentation] 反復性発熱・結節性紅斑・脂肪萎縮を特徴とする新規自己炎症性症候群の原因遺伝子同定2011
- Author(s)
  北村明子、安友康二
- Organizer
  第114回小児科学会総会
- Place of Presentation
  グランドプリンスホテル高輪(東京都)
- Year and Date
  2011-08-14
- Data Source
  KAKENHI-PROJECT-23791179
[Presentation] Identification of a candidate locus in familial systemic lupuservthematosus by homozygosity mapping2009
- Author(s)
  北村明子
- Organizer
  American Society of Human Genetics 2009 Annual Meeting
- Place of Presentation
  ハワイコンベンションセンター(アメリカ)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21790991
[Presentation] Identification of a candidate locus in familial systemic lupus erythematosus by homozygosity mapping2009
- Author(s)
  Akiko Kitamura, Koji Yasutomo
- Organizer
  American Society of Human Genetics 2009 Annual Meeting
- Place of Presentation
  Hawaii Convention Center (USA)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21790991
[Presentation] ホモ接合体マッピングによる家族性全身性エリテマトーデスの疾患遺伝子探索2009
- Author(s)
  北村明子、安友康二
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  グランドプリンスホテル高輪(東京)
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-21790991

1. 安友康二

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

KITAMURA Akiko 北村 明子

Research Projects

Research Products

Co-Researchers

NLRC4インフラマソームの機能異常による自己炎症病態の分子基盤解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarifying the molecular mechanism of autoinflammation caused by dysfunction of immunoproteasome complexesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of a critical gene involved in the pathogenesis of systemic lupus erythematosus by linkage analysis and exome resequencingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome-wide search for a candidate gene in systemic lupus erythematosusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of causative genes for hereditary renal diseases based on inbreeding coefficientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 先天性・乳児ネフローゼ症候群2008

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Manipulation of CD98 resolves type 1 diabetes in nonobese diabetic mice2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Notch2 regulates the development of marginal zone B cells through Fos2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Notch signaling regulates the development of a novel type of Thy1-expressing dendritic cell in the thymus.2011

Author(s)

Journal Title

Data Source

[Journal Article] A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor.2010

Author(s)

Journal Title

Data Source

[Journal Article] Notch2 signaling is required for potent anti-tumor immunity in vivo.2010

Author(s)

Journal Title

Data Source

[Journal Article] ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis.2010

Author(s)

Journal Title

Data Source

[Journal Article] 全身性エリテマトーデスの原因遺伝子2009

Author(s)

Journal Title

Data Source

[Journal Article] Jagged1 suppresses collagen-induced arthritis by indirectly providing a negative signal in CD8+ T cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] Predisposition to relapsing nephrotic syndrome by a nephrin mutation that interferes with assembly of functioning microdomains.2009

Author(s)

KITAMURA Akiko 北村明子