SHIMOKAWA Naomi 下川直美

Researcher Number	10452129
Affiliation (based on the past Project Information) *help	2011: 山梨大学, 医学工学総合研究部, 助教 2008 – 2009: University of Yamanashi, 大学院・医学工学総合研究部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Dermatology
Keywords	Principal Investigator 肝臓学 / 皮膚免疫学 / 再生学 / 皮膚炎症

Research Projects
(2 results)
Research Products
(18 results)

肝転移腫瘍における転移巣浸潤CD8+T細胞の役割解明Principal Investigator
- Principal Investigator
  
  下川直美
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Yamanashi
The role of IL-12 family proteins in connective tissue-type mast cellsPrincipal Investigator
- Principal Investigator
  
  SHIMOKAWA Naomi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi

All 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Opposite effects of Trichostatin A on activation of mast cells by different stimulants.2010
- Author(s)
  Wang QH, Nishiyama C, Nakano N, Kanda S, Hara M, Kitamura N, Shimokawa N, Lu CL, Ogawa H, Okumura K
- Journal Title
  
  FEBS Lett 584(11)
  
  Pages: 2315-2320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Suppressive effects of transcription factor GATA-1 on cell type-specific gene expression in dendritic cells.2010
- Author(s)
  Shimokawa N, Nishiyama C, Nakano N, Maeda K, Suzuki R, Hara M, Tokura T, Miyajima H, Nakao A, Ogawa H, Okumura K
- Journal Title
  
  Immunogenetics (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Activation of the aryl hydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice.2010
- Author(s)
  Takamura T, Harama D, Matsuoka S, Shimokawa N, Nakamura Y, Okumura K, Ogawa H, Kitamura M, Nakao A
- Journal Title
  
  Immunology and Cell Biology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Functional analysis of a polymorphism in the promoter region of the IL-12/23p40 gene.2009
- Author(s)
  Shimokawa N, Nishiyama C, Hirota T, Tamari M, Hara M, Ikeda S, Okumura K, Ogawa H
- Journal Title
  
  Clin Exp Allergy 39(2)
  
  Pages: 228-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] A sub-cytotoxic dose of subtilase cytotoxin prevents LPS-induced inflammatory responses, depending on its capacity to induce the unfolded protein response.2009
- Author(s)
  Harama D, Koyama K, Mukai M, Shimokawa N, Miyata M, Nakamura Y, Ohnuma Y, Ogawa H, Matsuoka S, Paton AW, Paton JC, Kitamura M, Nakao A
- Journal Title
  
  J Immunol 183(2)
  
  Pages: 1368-1374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] House dust mite allergen Der f 1 can induce the activation of latent TGFβvia its protease activity.2009
- Author(s)
  Nakamura Y, Miyata M, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Okumura K, Nakao A
- Journal Title
  
  FEBS Letters 583(12)
  
  Pages: 2088-2092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Thymic stromal lymphopoietin is a critical mediator of IL-13-driven allergic inflammation.2009
- Author(s)
  Miyata M, Nakamura Y, Shimokawa N, Ohnuma Y, Katoh R, Matsuoka S, Okumura K, Ogawa H, Masuyama K, Nakao A
- Journal Title
  
  Eur J Immunol 39(11)
  
  Pages: 3078-3083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Transforming growth factor-βactivity in commercially available pasteurized cow milk provides protection against inflammation in mice.2009
- Author(s)
  Ozawa T, Miyata M, Nishimura M, Ando T, Ouyang Y, Ohba T, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Nakao A
- Journal Title
  
  J Nutr 139(1)
  
  Pages: 69-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Functional analysis of a polymorphism in the promoter region of the IL-12/23p40 gene.2009
- Author(s)
  Shimokawa Naomi
- Journal Title
  
  Clin Exp Allergy 39
  
  Pages: 228-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] The latent form of transforming growth factor-βadministered orally is activated by gastric acid in mice.2009
- Author(s)
  Nakamura Y, Miyata M, Ando T, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Okumura K, Nakao A
- Journal Title
  
  J Nutr 139(8)
  
  Pages: 1463-1468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Suppressive effect of Elf-1 on FcepisilonRI alpha-chain expression in primary mast cells.2008
- Author(s)
  Wang QH, Nishiyama C, Nakano N, Shimokawa N, Hara M, Kanda S, Ogawa H, Okumura K
- Journal Title
  
  Immunogenetics 60(10)
  
  Pages: 557-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to TH2-type immune responses and airway inflammation.2008
- Author(s)
  Nakamura Y, Miyata M, Ohba T, Ando T, Hatsushika K, Suenaga F, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Nakao A
- Journal Title
  
  J Allergy Clin Immun 122(6)
  
  Pages: 1208-1214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Mast cell regulation of epithelial TSLP expression plays an important role in the development of allergic rhinitis.2008
- Author(s)
  Miyata M, Hatsushika K, Ando T, Shimokawa N, Ohnuma Y, Katoh R, Suto H, Ogawa H, Masuyama K, Nakao A
- Journal Title
  
  Eur J Immunol 38(6)
  
  Pages: 1487-1492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Journal Article] Two Different Transcription Factors Discriminate the -315C>T Polymorphism of the FcεRIαGene: Binding of Sp1 to -315C and of a High Mobility Group-Related Molecule to -315T.2008
- Author(s)
  Kanada S, Nakano N, Potaczek DP, Maeda K, Shimokawa N, Niwa Y, Fukai T, Sanak M, Szczeklik A, Yagita H, Okumura K, Ogawa H, Nishiyama C
- Journal Title
  
  J Immunol 180(12)
  
  Pages: 8204-8210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790793
[Presentation] 肝転移腫瘍における転移巣浸潤CD8+T細胞の役割解明2011
- Author(s)
  下川直美
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉市)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23790784
[Presentation] Role of a transcription factor GATA-1 in commitment between dentritic cells and mast cells.2008
- Author(s)
  Shimokawa N, Nishiyama C, Nakao A, Okumura K, Ogawa H
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20790793
[Presentation] IL-12/23 p40遺伝子のプロモーター領域における遺伝子多型の機能解析2008
- Author(s)
  下川直美, 西山千春, 広田朝光, 玉利真由美, 池田志斈, 奥村康, 小川秀輿
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20790793
[Presentation] Cigarette smoke extract induce TSLP expression, leading to allergic airway inflammation.2008
- Author(s)
  Nakamura Y, Miyata M, Shimokawa N, Ogawa H, Nakao A
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20790793

SHIMOKAWA Naomi 下川 直美

Research Projects

Research Products

肝転移腫瘍における転移巣浸潤CD8+T細胞の役割解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of IL-12 family proteins in connective tissue-type mast cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Opposite effects of Trichostatin A on activation of mast cells by different stimulants.2010

Author(s)

Journal Title

Data Source

[Journal Article] Suppressive effects of transcription factor GATA-1 on cell type-specific gene expression in dendritic cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Activation of the aryl hydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice.2010

Author(s)

Journal Title

Data Source

[Journal Article] Functional analysis of a polymorphism in the promoter region of the IL-12/23p40 gene.2009

Author(s)

Journal Title

Data Source

[Journal Article] A sub-cytotoxic dose of subtilase cytotoxin prevents LPS-induced inflammatory responses, depending on its capacity to induce the unfolded protein response.2009

Author(s)

Journal Title

Data Source

[Journal Article] House dust mite allergen Der f 1 can induce the activation of latent TGFβvia its protease activity.2009

Author(s)

Journal Title

Data Source

[Journal Article] Thymic stromal lymphopoietin is a critical mediator of IL-13-driven allergic inflammation.2009

Author(s)

Journal Title

Data Source

[Journal Article] Transforming growth factor-βactivity in commercially available pasteurized cow milk provides protection against inflammation in mice.2009

Author(s)

Journal Title

Data Source

[Journal Article] Functional analysis of a polymorphism in the promoter region of the IL-12/23p40 gene.2009

Author(s)

Journal Title

Data Source

[Journal Article] The latent form of transforming growth factor-βadministered orally is activated by gastric acid in mice.2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppressive effect of Elf-1 on FcepisilonRI alpha-chain expression in primary mast cells.2008

Author(s)

Journal Title

Data Source

[Journal Article] Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to TH2-type immune responses and airway inflammation.2008

Author(s)

Journal Title

Data Source

[Journal Article] Mast cell regulation of epithelial TSLP expression plays an important role in the development of allergic rhinitis.2008

Author(s)

Journal Title

Data Source

[Journal Article] Two Different Transcription Factors Discriminate the -315C>T Polymorphism of the FcεRIαGene: Binding of Sp1 to -315C and of a High Mobility Group-Related Molecule to -315T.2008

Author(s)

Journal Title

Data Source

[Presentation] 肝転移腫瘍における転移巣浸潤CD8+T細胞の役割解明2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Role of a transcription factor GATA-1 in commitment between dentritic cells and mast cells.2008

Author(s)

Organizer

SHIMOKAWA Naomi 下川直美