Miyake Yasuyuki 三宅康之

Researcher Number	10452294
Other IDs
Affiliation (Current)	2026: 名古屋大学, 医学系研究科, 特任准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 名古屋大学, 医学系研究科, 特任准教授 2020 – 2022: 名古屋大学, 医学系研究科, 助教 2019: 名古屋大学, 医学系研究科, 特別研究員(RPD)
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Virology
Keywords	Principal Investigator TNPO1 / インフルエンザウイルス / 細胞内侵入 / M1 / 脱殻 / RNAポリメラーゼ / vRNPs / ナノボディー / VP40 / M1 shell … More / USP7 / ユビキチン / HDAC6 / タンパク質構造 / タンパク質発現 / 複合体構造 / マトリクスタンパク質 / HIV-1 / CA / 創薬基盤 / 分子機能 / ヒト免疫不全症候群ウイルス Less

Research Projects
(3 results)
Research Products
(24 results)

Molecular mechanism of uncoating in RNA virusesPrincipal Investigator
- Principal Investigator
  
  三宅康之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Nagoya University
Molecular mechanisms of viral uncoating in influenza A virus and HIV-1Principal Investigator
- Principal Investigator
  
  Miyake Yasuyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Nagoya University
Molecular mechanisms of influenza virus uncoating by ubiquitin signalsPrincipal Investigator
- Principal Investigator
  
  三宅康之
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Virology
- Research Institution
  Nagoya University

All 2025 2024 2023 2022 2019 2018

All Journal Article Presentation Book

[Book] 月刊　細胞2022
- Author(s)
  三宅　康之
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K07513
[Book] Influenza Virus Methods and Protocols2018
- Author(s)
  Yasuyuki Miyake, Patrick Matthias, and Yohei Yamauchi
- Total Pages
  14
- Publisher
  Humana Press
- ISBN
  9781493986774
- Data Source
  KAKENHI-PROJECT-18J40214
[Journal Article] Influenza A Virus: Cellular Entry2023
- Author(s)
  Yasuyuki Miyake, Yuya Hara, Miki Umeda, Indranil Banerjee
- Journal Title
  
  Subcellular Biochemistry
  
  Volume: 106 Pages: 387-401
- DOI
  10.1007/978-3-031-40086-5_14
- ISBN
  9783031400858, 9783031400865
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06572
[Journal Article] Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways.2022
- Author(s)
  Wang L., Moreira E.A., Kempf G., Miyake Y., Esteves B.I.O., Fahmi A., Schaefer J.V., Dreier B., Yamauchi Y., Alves M.P., Plueckthun A., and Matthias P.
- Journal Title
  
  Cell Reports
  
  Volume: 39 Issue: 4 Pages: 110736-110748
- DOI
  10.1016/j.celrep.2022.110736
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07513
[Journal Article] インフルエンザウイルスの細胞内侵入の生化学2022
- Author(s)
  三宅康之、山内洋平
- Journal Title
  
  生化学
  
  Volume: 94 Pages: 427-432
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07513
[Journal Article] インフルエンザウイルスの細胞内侵入に関わる宿主因子の分子機能2022
- Author(s)
  三宅康之
- Journal Title
  
  細胞
  
  Volume: 54 Pages: 48-49
- Data Source
  KAKENHI-PROJECT-20K07513
[Journal Article] Influenza virus uses transportin 1 for vRNP debundling during cell entry2019
- Author(s)
  Miyake Y, Keusch J, Decamps L, Ho-Xuan H, Iketani S, Gut H, Kutay U, Helenius A, and Yamauchi Y
- Journal Title
  
  Nature Microbiology
  
  Volume: 4 Issue: 4 Pages: 578-586
- DOI
  10.1038/s41564-018-0332-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J40214
[Presentation] インフルエンザウイルス感染におけるウイルス凝集体の形成に対する宿主因子Transportinの機能解明2025
- Author(s)
  鷲澤拓登、Carl Winn、三宅康之、木村宏、山内洋平
- Organizer
  APPW2025
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] Detailed insights on the interaction between Influenza A Virus Matrix Protein M1 and the host-cell factor Transportin-1 during the Influenza A Virus genome debundling.2024
- Author(s)
  Atzin Bolanos-Ceron, Yasuyuki Miyake, and Hiroshi Kimura
- Organizer
  第37回インフルエンザ研究者交流の会シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] Molecular insights into assembled genome structure of influenza A virus during uncoating2024
- Author(s)
  Yasuyuki Miyake, Yuya Hara, Aya Yanou, Kentaro Hiraka, Kazuyoshi Murata, Takayuki Uchihashi, Jiro Usukura, Hiroshi Kimura, Yohei Yamauchi
- Organizer
  World Flu Day 2024 Symposium / 9th Japan-China Bilateral Symposium on All Influenza Viruses (WFD-CJS2024)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] Insights into understanding the debundling mechanisms behind the complex formation between host factor Transportin-1 and the Influenza A Virus Matrix protein M12024
- Author(s)
  Atzin Bolanos-Ceron, Yasuyuki Miyake, and Hiroshi Kimura
- Organizer
  第71回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] A型インフルエンザウイルスの脱殻におけるゲノム集合体構造の役割2024
- Author(s)
  三宅康之、矢能彩、原優矢、Atzin Bolanos-Ceron、平賀健太郎、村田和義、内橋貴之、臼倉治郎、木村宏、Yohei Yamauchi
- Organizer
  第37回インフルエンザ研究者交流の会シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] Molecular insight into vRNP structure during influenza A virus uncoating2024
- Author(s)
  三宅康之、鷲澤拓登、矢能彩、原優矢、Atzin Bolanos-Ceron、平賀健太郎、村田和義、内橋貴之、臼倉治郎、木村宏、Yohei Yamauchi
- Organizer
  第71回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] A型インフルエンザウイルスのウイルスゲノム複合体の集合・乖離に関する分子的洞察2023
- Author(s)
  矢能彩, 原優矢, 三宅康之, Aztin Bolanos-Ceron, 山内洋平, 木村宏
- Organizer
  第４６回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] RNAウイルスの脱殻におけるエンドソーム酸性化の役割2023
- Author(s)
  原優矢, 矢能彩, 梅田実希, Atzin Bolanos-Ceron, 木村宏, 山内洋平, 三宅康之
- Organizer
  第４６回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] 宿主脱ユビキチン化酵素USP7とヒストン脱アセチル化酵素HDAC6はA型インフルエンザウイルスの脱殻時に機能する2023
- Author(s)
  稲垣滉一, Alina Rozanova, 三宅康之, 渡辺崇広, 梅田実希, Atzin Bolanos-Ceron, 山内洋平, 木村宏
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06572
[Presentation] Elucidating the interactions between Influenza A Matrix Protein M1 and host cell factor Transportin-1 during vRNP debundling2022
- Author(s)
  Atzin Bolanos-Ceron, Yasuyuki Miyake, Yohei Yamauchi, Hiroshi Kimura
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07513
[Presentation] 宿主タンパク質を介したウイルス脱殻反応の分子機構解明2022
- Author(s)
  原優矢, 三宅康之, 山内洋平, 木村宏
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07513
[Presentation] INSIGHTS INTO INFLUENZA A VIRUS VRNP DEBUNDLING2022
- Author(s)
  Yuya Hara, Hiroshi Kimura, Yasuyuki Miyake, Yohei Yamauchi
- Organizer
  Negative Strand Virus Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07513
[Presentation] HOW INFLUENZA A VIRUS MATRIX PROTEIN M1 INTERACTS WITH HOST CELL FACTOR TRANSPORTIN-1 DURING VRNP DEBUNDLING2022
- Author(s)
  Atzin Ceron, Yasuyuki Miyake, Yohei Yamauchi, Hiroshi Kimura
- Organizer
  Negative Strand Virus Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07513
[Presentation] Development of Anti-Histone Deacetylase 6 (HDAC6) Nanobodies and DARPins as Inhibitors of Influenza Virus Infection2019
- Author(s)
  Yasuyuki Miyake
- Organizer
  1st Bonn Nanobody Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J40214
[Presentation] Influenza virus uses Transportin 1 (TNPO1) for vRNP debundling during cell entry2019
- Author(s)
  Yasuyuki Miyake, Jeremy Keusch, Laure Decamps, Hung Ho-Xuan, Sho Iketani, Heinz Gut, Ulrike Kutay, Ari Helenius, and Yohei Yamauchi
- Organizer
  JSPS Core-to-Core program, The 2nd Symposium on Virus Infection and Host Response
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J40214
[Presentation] Influenza virus uses Transportin 1 (TNPO1) for vRNP debundling during cell entry2018
- Author(s)
  Yasuyuki Miyake, Jeremy Keusch, Laure Decamps, Hung Ho-Xuan, Sho Iketani, Heinz Gut, Ulrike Kutay, Ari Helenius, and Yohei Yamauchi
- Organizer
  ASCB|EMBO 2018 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J40214
[Presentation] Influenza virus uses Transportin 1 (TNPO1) for vRNP debundling during cell entry2018
- Author(s)
  Yasuyuki Miyake, Jeremy Keusch, Laure Decamps, Hung Ho-Xuan, Sho Iketani, Heinz Gut, Ulrike Kutay, Ari Helenius, and Yohei Yamauchi
- Organizer
  Influenza Update Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J40214

Miyake Yasuyuki 三宅 康之

Research Projects

Research Products

Molecular mechanism of uncoating in RNA virusesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of viral uncoating in influenza A virus and HIV-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of influenza virus uncoating by ubiquitin signalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 月刊 細胞2022

Author(s)

Publisher

Data Source

[Book] Influenza Virus Methods and Protocols2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Influenza A Virus: Cellular Entry2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] インフルエンザウイルスの細胞内侵入の生化学2022

Author(s)

Journal Title

Data Source

[Journal Article] インフルエンザウイルスの細胞内侵入に関わる宿主因子の分子機能2022

Author(s)

Journal Title

Data Source

[Journal Article] Influenza virus uses transportin 1 for vRNP debundling during cell entry2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] インフルエンザウイルス感染におけるウイルス凝集体の形成に対する宿主因子Transportinの機能解明2025

Author(s)

Organizer

Data Source

[Presentation] Detailed insights on the interaction between Influenza A Virus Matrix Protein M1 and the host-cell factor Transportin-1 during the Influenza A Virus genome debundling.2024

Author(s)

Organizer

Data Source

[Presentation] Molecular insights into assembled genome structure of influenza A virus during uncoating2024

Author(s)

Organizer

Data Source

[Presentation] Insights into understanding the debundling mechanisms behind the complex formation between host factor Transportin-1 and the Influenza A Virus Matrix protein M12024

Author(s)

Organizer

Data Source

[Presentation] A型インフルエンザウイルスの脱殻におけるゲノム集合体構造の役割2024

Author(s)

Organizer

Data Source

[Presentation] Molecular insight into vRNP structure during influenza A virus uncoating2024

Author(s)

Organizer

Data Source

[Presentation] A型インフルエンザウイルスのウイルスゲノム複合体の集合・乖離に関する分子的洞察2023

Miyake Yasuyuki 三宅康之

[Book] 月刊　細胞2022