Nakamura Hideaki 中村秀明

Researcher Number	10452616
Other IDs
Affiliation (Current)	2025: 佐賀大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2025: 佐賀大学, 医学部附属病院, 助教 2018 – 2022: 佐賀大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 52010:General internal medicine-related / Basic Section 54030:Infectious disease medicine-related
Keywords	Principal Investigator 遺伝子発現解析 / ATL病期進展リスク評価 / 成人T細胞白血病(ATL) / リスク評価 / 成人T細胞白血病・リンパ腫 / マルチプレックスRT-PCR / マルチプレックスPCR / ATL / HTLV-1 Except Principal Investigator 早期発見 … More / 微小残存腫瘍検出 / 血中腫瘍由来循環DNA / HTLV-1 / ATL / 保存 / 品質 / NGS / 遺伝子検査 / 品質管理 / cfDNA / Liquid biopsy Less

HTLV-1持続潜伏感染を標的とした新規治療戦術確立へ向けた基盤研究
- Principal Investigator
  
  佐藤賢文
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
がんの早期発見や術後の微小残存腫瘍検出における血中腫瘍由来循環DNAの可能性
- Principal Investigator
  
  佐藤明美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Saga University
Development of a multiplex RT-PCR method to assess the risk of stage progression in adult T-cell leukemia/lymphomaPrincipal Investigator
- Principal Investigator
  
  Nakamura Hideaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Saga University
Construction of cfDNA quality management and quality check system in genetic testing
- Principal Investigator
  
  Sato Akemi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Saga University

All 2022 2021 2020 2018

All Journal Article Presentation

[Journal Article] Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism2022
- Author(s)
  Nakamura Hideaki、Sekine Hiroki、Kato Hiroyuki、Masai Hisao、Gradin Katarina、Poellinger Lorenz
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 7 Pages: 102137-102137
- DOI
  10.1016/j.jbc.2022.102137
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0157, KAKENHI-PROJECT-20K07700, KAKENHI-PROJECT-20K21410, KAKENHI-PUBLICLY-21H00264, KAKENHI-PUBLICLY-22H04707, KAKENHI-PROJECT-20H00463
[Journal Article] HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma2021
- Author(s)
  Tan Benjy J.Y.、Sugata Kenji et al.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 24
- DOI
  10.1172/jci150472
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22783, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-20H03724, KAKENHI-PROJECT-20K07700, KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-21K08494
[Journal Article] Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-21002020
- Author(s)
  Watanabe Tatsuro、Yamashita Satoshi、Ureshino Hiroshi、Kamachi Kazuharu、Kurahashi Yuki、Fukuda-Kurahashi Yuki、Yoshida Nao、Hattori Naoko、Nakamura Hideaki、Sato Akemi、Kawaguchi Atsushi、Sueoka-Aragane Naoko、Kojima Kensuke、Okada Seiji、Ushijima Toshikazu、Kimura Shinya、Sueoka Eisaburo
- Journal Title
  
  Blood
  
  Volume: 136 Issue: 7 Pages: 871-884
- DOI
  10.1182/blood.2019003084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07593, KAKENHI-PROJECT-20K07700, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K17860
[Journal Article] Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy2018
- Author(s)
  3.Sato A, Nakashima C, Abe T, Kato J, Hirai M, Nakamura T, Komiya K, Kimura S, Sueoka E, Sueoka-Aragane N
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 61 Pages: 31904-31914
- DOI
  10.18632/oncotarget.25881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07197, KAKENHI-PROJECT-18K07451, KAKENHI-PROJECT-16K09850
[Presentation] Biological significance of pyrimidine metabolism enzyme UCK2 of HTLV-1-infected cells in ATL leukemogenesis2022
- Author(s)
  渡邉達郎、嬉野博志、中村秀明、末岡榮三朗、木村晋也
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] フローサイトメーターを用いた解析(HAS-Flow)によるHTLV-1感染者の臨床経過モニタリング2022
- Author(s)
  中村秀明、末岡榮三朗
- Organizer
  第69回日本臨床検査医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] ATL 発がんにおけるピリミジンヌクレオチド代謝酵素 UCK2 の関与2022
- Author(s)
  渡邉達郎、吉田‐坂井奈央、山本雄大、嬉野博志、蒲池和晴、倉橋祐樹、川副和紀、倉橋佑紀、中村秀明、岡田誠治、末岡榮三朗、木村晋也
- Organizer
  第8回日本HTLV-1学術集会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] HTLV-1 hijacks T-cell activation mechanisms for leukemic transformation as revealed by scRNA-seq2021
- Author(s)
  タン　ベンジー　ジェック　ヤン、菅田謙治、Omnia Reda、松尾美沙希、宮里パオラ、Vincent Hahaut、鈴島仁、勝屋弘雄、徳永雅仁、内山良一、中村秀明、末岡榮三朗、宇都宮與、小野昌弘、佐藤賢文
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] キャリアおよび indolent ATL の臨床経過モニタリングにおける HAS-Flow 法の意義2021
- Author(s)
  中村秀明、佐藤明美、渡邉達郎、末岡榮三朗
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] メチオニン代謝を介した HTLV-1 感染細胞のエピゲノム調節2021
- Author(s)
  渡邉達郎，吉田奈央，山本雄大，嬉野博志，蒲池和晴，倉橋祐樹，倉橋佑紀，中村秀明，服部奈緒子，山下聡，岡田誠治，牛島俊和，末岡榮三朗，木村晋也
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] ATL に対する DNA 脱メチル化剤と EZH2 阻害剤の併用効果とその標的因子 DUSP5 の機能解析2021
- Author(s)
  倉橋祐樹，吉田奈央，嬉野博志，蒲池和晴，山本雄大，中村秀明，渡邉達郎，末岡榮三朗，木村晋也
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] 成人 T 細胞白血病/リンパ腫におけるメチオニンを介したエピジェネティクス制御2021
- Author(s)
  渡邉達郎、嬉野博志、中村秀明、末岡榮三朗、木村晋也
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] 成人 T 細胞白血病/リンパ腫におけるメチオニン代謝改変を介したエピジェネティクス異常2021
- Author(s)
  渡邉達郎、吉田奈央、山本雄大、蒲池和晴、倉橋祐樹、倉橋佑紀、嬉野博志、中村秀明、末岡榮三朗、木村晋也
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] 胸腺過形成，低ガンマグロブリン血症を有する成人 T 細胞白血病患者において異なる発症形式を示した赤芽球癆2021
- Author(s)
  Yasushi Kubota, Haruhiko Sano, Kyosuke Yamaguchi, Hideaki Nakamura, Keita Kai, Kesisuke Kidoguchi, Kana Kusaba, Haruna Kizuka-Sano, Masako Yokoo, Toshihiko Ando, Eisaburo Sueoka, Shinya Kimura
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07700
[Presentation] 遺伝子検査におけるcirculating free DNAの保存条件に関する検討2018
- Author(s)
  佐藤明美、中島千穂、安部友範、中村秀明、荒金尚子、木村　晋也、末岡榮三朗
- Organizer
  日本臨床検査自動化学会第50回大会
- Data Source
  KAKENHI-PROJECT-18K07451
[Presentation] Liquid biopsyのためのプレアナリシス段階の検体品質管理に関する検討2018
- Author(s)
  佐藤明美、中島千穂、安部友範、中村秀明、荒金尚子、木村　晋也、末岡榮三朗
- Organizer
  第58回日本臨床化学会年時学術集会
- Data Source
  KAKENHI-PROJECT-18K07451

1. Sato Akemi (20568357)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. 末岡榮三朗 (00270603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. 勝屋弘雄 (80632041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 佐藤賢文 (70402807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 梅北邦彦 (20506084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 吉満誠 (70404530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中畑新吾 (80437938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 小楠真典 (40764676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中島千穂 (40858502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 服部奈緒子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渡邉達郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 正井久雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 菅田謙治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 末岡尚子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 中村朝美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Hideaki 中村 秀明

Research Projects

Research Products

Co-Researchers

HTLV-1持続潜伏感染を標的とした新規治療戦術確立へ向けた基盤研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がんの早期発見や術後の微小残存腫瘍検出における血中腫瘍由来循環DNAの可能性

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a multiplex RT-PCR method to assess the risk of stage progression in adult T-cell leukemia/lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of cfDNA quality management and quality check system in genetic testing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-21002020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Biological significance of pyrimidine metabolism enzyme UCK2 of HTLV-1-infected cells in ATL leukemogenesis2022

Author(s)

Organizer

Data Source

[Presentation] フローサイトメーターを用いた解析(HAS-Flow)によるHTLV-1感染者の臨床経過モニタリング2022

Author(s)

Organizer

Data Source

[Presentation] ATL 発がんにおけるピリミジンヌクレオチド代謝酵素 UCK2 の関与2022

Author(s)

Organizer

Data Source

[Presentation] HTLV-1 hijacks T-cell activation mechanisms for leukemic transformation as revealed by scRNA-seq2021

Author(s)

Organizer

Data Source

[Presentation] キャリアおよび indolent ATL の臨床経過モニタリングにおける HAS-Flow 法の意義2021

Author(s)

Organizer

Data Source

[Presentation] メチオニン代謝を介した HTLV-1 感染細胞のエピゲノム調節2021

Author(s)

Organizer

Data Source

[Presentation] ATL に対する DNA 脱メチル化剤と EZH2 阻害剤の併用効果とその標的因子 DUSP5 の機能解析2021

Author(s)

Organizer

Data Source

[Presentation] 成人 T 細胞白血病/リンパ腫におけるメチオニンを介したエピジェネティクス制御2021

Author(s)

Organizer

Data Source

Nakamura Hideaki 中村秀明