ITO Koji 伊藤浩司

Researcher Number	10452757
Affiliation (based on the past Project Information) *help	2015 – 2016: 九州大学, 医学(系)研究科(研究院), 共同研究員 2011 – 2014: 九州大学, 医学(系)研究科(研究院), 学術研究員 2013: 九州大学, 医学(系)研究科(研究院), 研究員 2012: 九州大学, 医学研究院, 学術研究員 2012: 九州大学, 大学院・医学研究院, 学術研究員 … More 2010: Kyushu University, 大学病院, 助教 2008 – 2009: Kyushu University, 医学研究院, 研究員 2007: Kyushu University, 大学病院, 医員 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator 心不全 / 食塩 / 交感神経活動 / 脳 / 食塩摂取 / 心脳　臓器連関 / 心脳臓器連関 / 交感神経 / シグマ受容体 / 認知機能障害 … More / 圧負荷 / 認知障害 / 脳・神経 / 生理学 / 循環器・高血圧 / 医療・福祉 / ナトリウムチャネル / ミネラルコルチコイド受容体 / 心肥大(心不全) / ミネラルコルチコイド / Naチャネル / Rho-kinase系 / Rho / 圧負荷心不全 / ENaC / 交感神経活性亢進 / 脳内Na感受性 / 心不全(高血圧性心臓病) … More Except Principal Investigator 薬理学 / 生理学 / 循環器・高血圧 / レニン-アンジオテンシン系 / レニンーアンジオテンシン系 / 免疫系 / 慢性炎症 / レニン－アンジオテンシン系 / 脳 / 交感神経系 / 心不全 / 血圧 / 機能的磁気共鳴画像 / 交感神経 / 慢性心不全 / 睡眠時無呼吸 Less

Heart-brain communication for salt-sensitive sympathoexcitation in heart failurePrincipal Investigator
- Principal Investigator
  
  Ito Koji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyushu University
Sympathetic activation in heart failure: Elucidation of a novel framework and the control mechanisms
- Principal Investigator
  
  Hirooka Yoshitaka
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Mechanisms of cognitive dysfunction in heart failurePrincipal Investigator
- Principal Investigator
  
  ITO Koji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
中枢性睡眠時無呼吸合併慢性心不全患者に対するfMRIを使用した延髄機能異常の解明
- Principal Investigator
  
  江島健一
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Abnormal brain Na handling contributes to salt-induced cardiac dysfunction in heart failure modelPrincipal Investigator
- Principal Investigator
  
  ITO Koji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
The role of brain Na sensitivity in sympathetic hyperactivation in heart failurePrincipal Investigator
- Principal Investigator
  
  ITO Koji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Cardiac sympathetic afferent stimulation induces salt-sensitive sympathoexcitation through hypothalamic epithelial Na+ channel activation.2015
- Author(s)
  Ito K, Hirooka Y, Sunagawa K
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 308 Issue: 5 Pages: H530-H539
- DOI
  10.1152/ajpheart.00586.2014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461112, KAKENHI-PROJECT-23220013
[Journal Article] Corticosterone-activated mineralocorticoid receptor contributes to salt-induced　sympathoexcitation in pressure overload mice.2014
- Author(s)
  Ito K, Hirooka Y, Sunagawa K.
- Journal Title
  
  Clinical Experimental Hypertension
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461112
[Journal Article] Corticosterone-activated mineralocorticoid receptor contributes to salt-induced sympathoexcitation in pressure overload mice.2014
- Author(s)
  Ito K, Hirooka Y, Sunagawa K.
- Journal Title
  
  Clin Exp Hypertens.
  
  Volume: 36 Issue: 8 Pages: 550-556
- DOI
  10.3109/10641963.2014.881841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220013, KAKENHI-PROJECT-24390198
[Journal Article] Central neuregulin-1/ErbB signaling modulates cardiac function via sympathetic activity in pressure overload-induced heart failure.2014
- Author(s)
  Matsukawa R, Hirooka Y, Ito K,　Honda N, Sunagawa K.
- Journal Title
  
  Journal of Hypertension
  
  Volume: 32 Pages: 817-825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390198
[Journal Article] Potential clinical application of recently discovered brain mechanisms involved in hypertension.2013
- Author(s)
  Hirooka Y, Kishi T, Ito K, Sunagawa K.
- Journal Title
  
  Hypertension
  
  Volume: 62 Pages: 995-1002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390198
[Journal Article] Brain sigma-1 receptor stimulation improves mental disorder and cardiac function in mice with myocardial infarction.2013
- Author(s)
  Ito K
- Journal Title
  
  Journal of Cradiovascular Pharmacology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790862
[Journal Article] Role of hypothalamic angiotensin type 1 receptors in pressure overload-induced mineralocorticoid receptor activation and salt-induced sympathoexcitation.2013
- Author(s)
  Ito K, Hirooka Y, Nakano M, Honda N, Matsukawa R, Sunagawa K.
- Journal Title
  
  Hypertens Res.
  
  Volume: 36 Issue: 6 Pages: 513-519
- DOI
  10.1038/hr.2012.221
- NAID
  10031189655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220013, KAKENHI-PROJECT-24390198
[Journal Article] Moxonidine-induced central sympathoinhibition improves prognosis in rats with hypertensive heart failure.2013
- Author(s)
  Honda N, Hirooka Y, Ito K, Matsukawa R, Shinohara K, Kishi T, Yasukawa K, Utsumi H, Sunagawa K.
- Journal Title
  
  J Hypertens
  
  Volume: 31 Issue: 11 Pages: 2300-2308
- DOI
  10.1097/hjh.0b013e328364a2a1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220013, KAKENHI-PROJECT-24390198, KAKENHI-PROJECT-25253005
[Journal Article] Mineralocorticoid receptors/epithelial Na(+) channels in the choroid plexus are involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats.2013
- Author(s)
  Nakano M, Hirooka Y, Matsukawa R, Ito K, Sunagawa K.
- Journal Title
  
  Hypertens Res.
  
  Volume: 36 Issue: 3 Pages: 277-284
- DOI
  10.1038/hr.2012.174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220013, KAKENHI-PROJECT-24390198
[Journal Article] Inhibition of neuregulin-1/ErbB signaling in the rostral ventrolateral medulla leads to hypertension through reduced nitric oxide synthesis.2013
- Author(s)
  Matsukawa R, Hirooka Y, Ito K, Sunagawa K.
- Journal Title
  
  Am J Hypertens
  
  Volume: 26 Issue: 1 Pages: 51-57
- DOI
  10.1093/ajh/hps005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220013, KAKENHI-PROJECT-24390198
[Journal Article] Sunagawa K Decreased brain sigma-1 receptor contributes to the relationship between heart failure and depression2012
- Author(s)
  Ito K, Hirooka Y, Matsukawa R, Nakano M
- Journal Title
  
  Cradiovasc Res
  
  Volume: 93 Pages: 33-40
- Data Source
  KAKENHI-PROJECT-23790862
[Journal Article] Blockade of MR Receptors Improves Salt-Induced LV Systolic Dysfunction through Attenuation of Enhanced Sympathetic Drive in Mice with Pressure Overload2010
- Author(s)
  Ito K, Hirooka Y, Sunagawa K
- Journal Title
  
  Journal of Hypertension (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790730
[Journal Article] Blockade of mineralocorticoid receptors improves salt-induced left-ventricular systolic dysfunction through attenuation of enhanced sympathetic drive in mice with pressure overload.2010
- Author(s)
  Ito K, Hirooka Y, Sunagawa K.
- Journal Title
  
  J Hypertens. 28
  
  Pages: 1449-1458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790730
[Journal Article] Acquisition of brain Na sensitivity contributes to salt-induced sympatho excitation and cardiac dysfunction in mice with pressure overload.2009
- Author(s)
  Ito K, et al.
- Journal Title
  
  Circulation Research 104(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890148
[Journal Article] Acquisition of brain Na sensitivity contributes to salt-induced sympathoexcitation and cardiac dysfunction in mice with pressure overload2009
- Author(s)
  Ito K, Hirooka Y, Sunagawa K
- Journal Title
  
  Circulation Research 104
  
  Pages: 1004-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890148
[Journal Article] Sunagawa K Brain sigma-1 receptor stimulation improves mental disorder and cardiac function in mice with myocardial infarction
- Author(s)
  Ito K, Hirooka Y
- Journal Title
  
  J Cradiovasc Pharmacol
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23790862
[Presentation] Pressure overlaod-induced cardiac hypertrophy increases TRPV1 in heart and BDNF in NTS, suggesting baroreflex disruption via the brain-to-heart axis.2016
- Author(s)
  Shibata R, Shinohara K, Ito K, Kishi T, Tsutsui H, Hirooka Y.
- Organizer
  第20回日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] Pressure overload-induced cardiac hypertrophy increases brain-derived neurotrophic factor in nucleus tractus solitarius suggesting disruption of the baroreflex via heart-to-brain axis.2015
- Author(s)
  Takenaka R, Ito K, Kishi T, Hirooka Y.
- Organizer
  第19回日本心不全学会学術集会
- Place of Presentation
  グランフロント大阪　ナレッジキャピタルコングレコンベンションセンター（大阪市北区）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] 心肥大モデルにおける食塩感受性交感神経活性化～神経性心脳連関の重要性2015
- Author(s)
  伊藤　浩司
- Organizer
  第44回日本心脈管作動物質学会
- Place of Presentation
  高松センタービル
- Year and Date
  2015-02-07
- Invited
- Data Source
  KAKENHI-PROJECT-25461112
[Presentation] Activation of hypothalamic mineralocorticoid receptor-independent epithelial sodium channels leads to salt sensitive hypertension in mouse model of metabolic syndrome.2015
- Author(s)
  Kunita-Takanezawa M, Ito K, Kishi T, Hirooka Y.
- Organizer
  Scientific Sessions 2015
- Place of Presentation
  Orlando（USA）
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] メタボリック症候群モデルマウスにおける食塩感受性高血圧の脳内機序においてミネラルコルチコイド受容体非依存性の脳内上皮性Naチャネル活性化が重要である．2015
- Author(s)
  髙根澤睦，伊藤浩司，岸拓弥，廣岡良隆
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  愛媛県県民文化会館（松山市道後町）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] 食事性肥満モデルマウスを用いたメタボリック症候群における食塩感受性高血圧の脳内機序の検討．2014
- Author(s)
  髙根澤睦，伊藤浩司，廣岡良隆，砂川賢二
- Organizer
  第50回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  和歌山県立医科大学生涯研修センター
- Year and Date
  2014-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] Cardiac sympathetic afferent reflexes stimulation causes salt sensitivity via upregulation of the hypothalamic TNF-ENaCs-AVP pathway.2014
- Author(s)
  Ito K, Hirooka Y, Sunagawa K.
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461112
[Presentation] メタボリック症候群モデルマウスにおける食塩感受性高血圧は脳内上皮型Naチャネル活性化を介している．2014
- Author(s)
  髙根澤睦，伊藤浩司，廣岡良隆，砂川賢二
- Organizer
  第35回日本循環制御医学会総会
- Place of Presentation
  九州大学医学部百年講堂
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] 高血圧における交感神経活性化：脳内低分子量G蛋白活性化の役割および圧負荷心における食塩感受性獲得脳内機構の解明2014
- Author(s)
  伊藤　浩司
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25461112
[Presentation] 腎除神経は高血圧性心不全ラットにおいて利尿作用により心機能障害を抑制し、生命予後を改善する．2013
- Author(s)
  本田修浩、廣岡良隆、伊藤浩司、砂川賢二
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] Both aldosterone and corticosterone contribute to high salt-induced sympathoexcitation via the hypothalamic MR activation in mice with pressure overload.2013
- Author(s)
  Ito K, Hirooka Y, Sunagawa K.
- Organizer
  International Symposium of Aldosterone and Related Substances in Hypertension
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25461112
[Presentation] 圧負荷モデルにおける食塩感受性交感神経活動亢進にはコルチコステロンによる視床下部ミネラルコルチコイド受容体活性化が関与する2013
- Author(s)
  伊藤浩司、廣岡良隆、砂川賢二
- Organizer
  第17回日本心血管内分泌代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25461112
[Presentation] 心脳連関による脳内Naチャネル活性化と食塩感受性獲得2013
- Author(s)
  伊藤浩司
- Organizer
  第23回日本病態生理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461112
[Presentation] Central sympathoinhibition by moxonidine attenuates brain oxidative stress, prevented cardiac dysfunction and improved prognosis in rats with hypertensive heart failure.2013
- Author(s)
  Honda N, Hirooka Y, Ito K, Matsukawa R, Sunagawa K.
- Organizer
  Scientific Sessions 2013
- Place of Presentation
  Dallas, TX, USA
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] ENaCs Contributes to Salt-induced Sympathoexcitation via Mineralocorticoid Receptor Activation and Insufficient Activation of CYP-EET Pathway in Mice with Pressure-overload2012
- Author(s)
  伊藤浩司
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  マリンメッセ福岡(福岡市)
- Data Source
  KAKENHI-PROJECT-23790862
[Presentation] Cardiac sympathetic afferents stimulation increases brain ENaCs, thereby concomitant salt loading leads to sympathoexcitation2012
- Author(s)
  Ito K, Hirooka Y, et al.
- Organizer
  Scientific Sessions 2012
- Place of Presentation
  Los Angels, CA, USA
- Year and Date
  2012-11-05
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] Deceased brain sigma-1 receptor contributes to mood and cognitive disorder in mice with heart failure.2012
- Author(s)
  伊藤浩司
- Organizer
  第29回国際心臓研究学会(ISHR)日本部会
- Place of Presentation
  九州大学医学部百年講堂(福岡)
- Data Source
  KAKENHI-PROJECT-23790862
[Presentation] Deceased brain sigma-1 receptor contributes to mood and cognitive disorder in mice with heart failure2012
- Author(s)
  伊藤浩司、廣岡良隆、砂川賢二
- Organizer
  第29回国際心臓研究学会(ISHR)日本部会
- Place of Presentation
  福岡
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-23790862
[Presentation] Activation of Brain Mineralocorticoid Receptors through both Aldosterone Synthesis and 11β-HSD-2 Deficiency Contributes to Salt-induced Sympathoexcitation in Mice with Pressure-overload2012
- Author(s)
  伊藤浩司
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際センター(福岡市)
- Data Source
  KAKENHI-PROJECT-23790862
[Presentation] The brain AT1R are responsible for sympathoexcitation associated with brain MR activation in mice with pressure overload after salt loading2012
- Author(s)
  Ito K, Hirooka Y, et al.
- Organizer
  Scientific Sessions 2012
- Place of Presentation
  Los Angels, CA, USA
- Year and Date
  2012-01-05
- Data Source
  KAKENHI-PROJECT-24390198
[Presentation] 心不全における脳内シグマ受容体減少は交感神経活性を増強して心不全増悪を来すとともにうつ状態を助長する2011
- Author(s)
  伊藤浩司、廣岡良隆、砂川賢二
- Organizer
  第12回 Neurocardiology Workshop
- Place of Presentation
  東京
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23790862
[Presentation] Enhanced aldosterone synthesis and insufficient activation of cyp2c2-EET in the brain contributes to the increased salt-sensitivity in pressure-overload model2010
- Author(s)
  伊藤浩司
- Organizer
  第14回日本心不全学会総会
- Place of Presentation
  東京
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] Acquisition of brain Na sensitivity in mice with LVH via ENaCs through MR activation : possible involvement in salt-induced sympathetic activation and cardiac dysfunction.2010
- Author(s)
  伊藤浩司
- Organizer
  Cardiovascular System Dynamics Society
- Place of Presentation
  福岡
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] LVHモデルでの脳内ENaCs活性化を介したNa感受性獲得機序～脳内Aldo合成-MR活性化とCYP-EET経路機能不全～2010
- Author(s)
  伊藤浩司
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] Acquisition of brain Na sensitivity in mice with LVH via ENaCs through MR activation: possible involvement in salt-induced sympathetic activation and cardiac dysfunction.2010
- Author(s)
  Ito K.
- Organizer
  Cardiovascular System Dynamics Society
- Place of Presentation
  福岡
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] LVHモデルでの脳内ENaCs活性化を介したNa感受性獲得機序-脳内Aldo合成-MR活性化とCYP-EET経路機能不全2010
- Author(s)
  伊藤浩司
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] Brain salt sensitivity in mice with LVH is enhanced via Rho-kinase pathway through ENaC activation2009
- Author(s)
  Ito K, Hirooka Y, Sunagawa K
- Organizer
  Experimental Biology 2009
- Place of Presentation
  New Orleans, U.S.A.
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] Enhanced brain Na sensitivity contributes to salt-induced sympathetic hyperactivation and deterioration of cardiac function in mice with LVH2009
- Author(s)
  Ito K, et.al.
- Organizer
  第73回日本循環器学会総会・学術集会
- Place of Presentation
  大阪市(日本)
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] Enhanced brain Na sensitivity contributes to salt-induced sympathetic hyper activation and deterioration of cardiac function in mice with LVH.2009
- Author(s)
  Ito K, et al.
- Organizer
  第73回日本循環器学会総会・学術集会
- Place of Presentation
  大阪市
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] Left ventricular Hypertrophy Enhances the Expression of Mineralocortic oid Receptor and Epithelial Na Channels in the Brain and Leads to Salt-sensitive Sympathetic Hyperactivation and Left Ventricular Dysfunction2009
- Author(s)
  Ito K, Hirooka Y, Sunagawa K
- Organizer
  Scientific Sessions of the American Heart Association (AHA 2009)
- Place of Presentation
  Orlando, U.S.A
- Year and Date
  2009-11-18
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] Dysregulation of brain MR-ENaCs pathway contributes to the acquisition of brain Na sensitivity in mice with LVH2009
- Author(s)
  Ito K, Hirooka Y, Sunagawa K
- Organizer
  日本心不全学会総会
- Place of Presentation
  福岡市(福岡県)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] エプレレノンは圧負荷モデルにおける脳内Na感受性亢進を抑制することによって食塩負荷に伴う交感神経活性化を軽減し心機能を改善する2009
- Author(s)
  伊藤浩司、廣岡良隆、松川龍一、西原正章、砂川賢二
- Organizer
  日本高血圧学会総会
- Place of Presentation
  大津市(滋賀県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21790730
[Presentation] High salt intake deteriorates cardiac function of hypertrophied heart, Possibly via the excessive sympathetic drive.2008
- Author(s)
  Ito K, et al.
- Organizer
  Experimental Biology 2008
- Place of Presentation
  サンデイェゴ市(アメリカ)
- Year and Date
  2008-04-06
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] Blockade of brain ENaC attenuated high salt induced cardiac dysfunction of hypertrophied heart via the attenuation of sympathetic activation.2008
- Author(s)
  Ito K, et al.
- Organizer
  International Society of Hypertension (ISH) 2008
- Place of Presentation
  ベルリン市(ドイツ)
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] High salt intake deteriorates cardiac function of hypertrophied heart, Possibly via the excessive sympathetic drive2008
- Author(s)
  Ito K, et.al.
- Organizer
  Experimental Biology 2008
- Place of Presentation
  サンディエゴ市(アメリカ)
- Year and Date
  2008-04-06
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] High-salt intake superimposed on left ventricular hypertrophy activates brain ENaC and leads to sympathetic hyperactivation and ventricular dysfunction.2008
- Author(s)
  Ito K, et al.
- Organizer
  American Heart Association (AHA)2008 Scientific Sessions
- Place of Presentation
  ニューオリンズ市(アメリカ)
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] 圧負荷左室肥大モデルで高食塩負荷がもたらす左心機能低下に脳内EN_aCを介したN_a感受性完進によって生じる交感神経活性化が関与する2008
- Author(s)
  伊藤浩司
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌市
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] High-salt intake superimposed on left ventricular hypertrophy activates brain ENaC and leads to sympathetic hyperactivation and ventricular dysfunction2008
- Author(s)
  Ito K, et.al.
- Organizer
  American Heart Association (AHA) 2008 Scientific Session
- Place of Presentation
  ニューオリンズ市(アメリカ)
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] Blockade of brain ENaC attenuated high salt induced cardiac dysfunction of hypertrophied heart via the attenuation of sympathetic activation2008
- Author(s)
  Ito K, et.al.
- Organizer
  International Society of Hypertension (ISH)2008
- Place of Presentation
  ベルリン市(ドイツ)
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19890148
[Presentation] 圧負荷左室肥大モデルで高食塩負荷がもたらす左心機能低下に脳内ENaCを介したNa感受性亢進によって生じる交感神経活性化が関与する2008
- Author(s)
  伊藤浩司, ほか
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌市(日本)
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19890148

1. Hirooka Yoshitaka (90284497)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. 岸拓弥 (70423514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. 江島健一 (20444804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 井手友美 (90380625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 砂川賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

ITO Koji 伊藤 浩司

Research Projects

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Co-Researchers

Heart-brain communication for salt-sensitive sympathoexcitation in heart failurePrincipal Investigator

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Sympathetic activation in heart failure: Elucidation of a novel framework and the control mechanisms

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Mechanisms of cognitive dysfunction in heart failurePrincipal Investigator

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中枢性睡眠時無呼吸合併慢性心不全患者に対するfMRIを使用した延髄機能異常の解明

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Abnormal brain Na handling contributes to salt-induced cardiac dysfunction in heart failure modelPrincipal Investigator

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The role of brain Na sensitivity in sympathetic hyperactivation in heart failurePrincipal Investigator

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[Journal Article] Cardiac sympathetic afferent stimulation induces salt-sensitive sympathoexcitation through hypothalamic epithelial Na+ channel activation.2015

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[Journal Article] Corticosterone-activated mineralocorticoid receptor contributes to salt-induced sympathoexcitation in pressure overload mice.2014

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[Journal Article] Corticosterone-activated mineralocorticoid receptor contributes to salt-induced sympathoexcitation in pressure overload mice.2014

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[Journal Article] Central neuregulin-1/ErbB signaling modulates cardiac function via sympathetic activity in pressure overload-induced heart failure.2014

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[Journal Article] Potential clinical application of recently discovered brain mechanisms involved in hypertension.2013

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[Journal Article] Brain sigma-1 receptor stimulation improves mental disorder and cardiac function in mice with myocardial infarction.2013

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[Journal Article] Role of hypothalamic angiotensin type 1 receptors in pressure overload-induced mineralocorticoid receptor activation and salt-induced sympathoexcitation.2013

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[Journal Article] Moxonidine-induced central sympathoinhibition improves prognosis in rats with hypertensive heart failure.2013

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[Journal Article] Mineralocorticoid receptors/epithelial Na(+) channels in the choroid plexus are involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats.2013

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ITO Koji 伊藤浩司

[Journal Article] Corticosterone-activated mineralocorticoid receptor contributes to salt-induced　sympathoexcitation in pressure overload mice.2014