Yachie Ayako 谷内江綾子

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YACHIE Ayako 谷内江綾子

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Researcher Number	10453549
Other IDs	https://orcid.org/0000-0003-2032-227X
Affiliation (Current)	2025: 特定非営利活動法人システム・バイオロジー研究機構, その他部局など, シニアサイエンティスト 2025: 大阪大学, ヒューマン・メタバース疾患研究拠点, 招へい教授
Affiliation (based on the past Project Information) *help	2014: 慶應義塾大学, 医学部, 共同研究員 2008 – 2009: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator General medical chemistry Except Principal Investigator Genome biology
Keywords	Principal Investigator 低酸素応答 / アデノシン / 保存血液 / 赤血球 / 細胞シミュレーション / 代謝シミュレーション / 代謝解析 / メタボローム / 血液保存 / シミュレーション / システム生物学 … More Except Principal Investigator … More 心筋梗塞 / メタボローム解析 / 虚血再灌流 / 低酸素応答 / メタボローム / 虚血再灌流傷害 / 代謝 / 低酸素 / iscemia / PHD / HIF / metabolomics / hypoxia Less

New concept for treatment of iscgemia/reperfusion injuries brought by metabolomics
- Principal Investigator
  
  MINAMISHIMA Yoji Andrew
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  Keio University
Prediction of metabolic dynamics in human erythrocytes based on a large-scale mathematical model and its verification by metabolome analysisPrincipal Investigator
- Principal Investigator
  
  YACHIE Ayako
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Keio University

All 2010 2009 2008

All Journal Article Presentation

[Journal Article] Hypotaurine is an energy-saving hepatoprotective compound against ischemia-reperfusion injury of the rat liver.2010
- Author(s)
  Sakuragawa, T., Hishiki, T., Ueno, Y., Ikeda, S., Soga, T., Yachie-Kinoshita, A.,Kajimura, M.,Suematsu, M
- Journal Title
  
  J Clin Biochem Nutr. 46(2)
  
  Pages: 126-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry Antioxid2010
- Author(s)
  Hattori, K., Kajimura, M., Hishiki, T., Nakanishi, T., Kubo, A., Nagahata, Y., Ohmura, M., Yachie-Kinoshita, A., Matsuura, T., Morikawa, T., Nakamura, T., Setou, M., Suematsu, M.
- Journal Title
  
  Redox Signal (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] T-state stabilization of hemoglobin by nitric oxide to form a-nitrosyl heme causes constitutive release of ATP from human erythrocytes2010
- Author(s)
  Akatsu, T., Tsukada, K., Hishiki, T., Suganuma, K., Tanabe, M., Shimazu, M., Kitagawa, Y., Yachie-Kinoshita, A., Suematsu, M.
- Journal Title
  
  Advances in Experimental Medicine and Biology 662
  
  Pages: 109-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] A Metabolic Model of Human Erythrocytes: Practical Application of the E-Cell Simulation Environment2010
- Author(s)
  Yachie-Kinoshita, A., Nishino, T., Shimo, H., Suematsu, M., Tomita, M.
- Journal Title
  
  J Biomed Biotechnol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] Hypotaurine is an energy-saving hepatoprotective compound against ischemia-reperfusion injury of the rat liver2010
- Author(s)
  Sakuragawa, T., Hishiki, T., Ueno, Y., Ikeda, S., Soga, T., Yachie-Kinoshita, A., Kajimura, M., Suematsu, M.
- Journal Title
  
  J. Clin. Biochem. Nutr. 46(2)
  
  Pages: 126-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] T-state stabilization of hemoglobin by nitric oxide to form alpha-nitrosyl heme causes constitutive release of ATP from human erythrocytes.2010
- Author(s)
  Akatsu T, Tsukada K, Hishiki T, Suga-Numa K, Tanabe M, Shimazu M,Kitagawa Y,Yachie-Kinoshita A, Suematsu M.
- Journal Title
  
  Adv Exp Med Biol. 66
  
  Pages: 109-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] In silico modeling and metabolome analysis of long-stored erythrocytes to improve blood storage methods2009
- Author(s)
  Nishino, T., Yachie-Kinoshita, A. * (* corresponding authour), Hirayama, A., Soga, T., Suematsu, M., Tomita, M.
- Journal Title
  
  J Biotechnol 144(3)
  
  Pages: 212-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] E-Cell systemによるヒト赤血球代謝シミュレーションの展開2009
- Author(s)
  西野泰子, 谷内江綾子, 冨田勝
- Journal Title
  
  人工血液 17(1)(掲載決定済、未刊行)
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] In silico modeling and metabolome analysis of long-stored erythrocytes to improve blood storage methods.2009
- Author(s)
  Nishino T, Yachie-Kinoshita A, Hirayama A, Soga T, Suematsu M, Tomita M.
- Journal Title
  
  J Biotechnol 114(3)
  
  Pages: 212-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790237
[Journal Article] E-Cell systemによるヒト赤血球代謝シミュレーションの展開2009
- Author(s)
  西野泰子谷内江綾子冨田勝
- Journal Title
  
  人工血液 17(1)
  
  Pages: 37-43
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] Mathematical modeling of preserved red blood cells towards improvement of blood storage2009
- Author(s)
  Nishino, T., Yachie-Kinoshita, A., Hirayama, A., Soga, T., Suematsu, M. Tomita, M
- Organizer
  The 10^<th> International Conference on Systems Biology
- Place of Presentation
  Stanford, CA, USA
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] シミュレーションとメタボローム解析による新規血液保存法の開発2009
- Author(s)
  西野泰子, 谷内江綾子, 平山明由, 曽我朋義, 末松誠, 冨田勝
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 赤血球代謝シミュレーションとメタボローム解析による新規血液保存法の開発2009
- Author(s)
  西野泰子, 谷内江綾子, 平山明由, 曽我朋義, 末松誠, 冨田勝
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 新規血液保存法の開発に向けた保存赤血球シミュレーションとメタボローム解析」2009
- Author(s)
  西野泰子, 谷内江綾子, 平山明由, 曽我朋義, 末松誠, 冨田勝
- Organizer
  第4回メタボロームシンポジウム
- Place of Presentation
  横浜市立横浜サイエンスフロンティア高等学校
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 網羅的代謝解析により強化された肝細胞代謝モデルの開発と応用2008
- Author(s)
  谷内江綾子藤木夏子福田亮末松誠
- Organizer
  Bio-SuperComputing Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 赤血球代謝モデルの応用と4D細胞シミュレーションへの拡張2008
- Author(s)
  谷内江綾子川原仁志西野泰子須永泰弘野田茂穂大日向大地横田秀夫末松誠
- Organizer
  Bio-SuperComputing Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 細胞における代謝の時空間シミュレーション2008
- Author(s)
  谷内江綾子, 川原仁志, 野田茂穂, 須永泰弘, 大日向大地, 横田秀夫, 末松誠
- Organizer
  BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] ヒト赤血球代謝シミュレーションとメタボローム技術によるMAP保存赤血球代謝の予測と解析2008
- Author(s)
  西野泰子, 谷内江綾子, 末松誠, 冨田勝
- Organizer
  BMB2008 第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 1st Joint Workshop on Computational Science2008
- Author(s)
  Yachie-Kinoshita, A., Noda, S., Yoshizawa, S., Yokota, H., Suematsu, M.
- Organizer
  Simulation on Temporospatial Dynamics of Cellular Metabolism
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] Simulation on Temporospatial Dynamics of Cellular Metabolism2008
- Author(s)
  Ayako Yachie-Kinoshita, Shigeho Noda, Shin Yoshizawa, Hideo Yokota and Makoto Suematsu
- Organizer
  1st Joint Workshop on Computational Science
- Place of Presentation
  和光市
- Year and Date
  2008-07-08
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] ヒト赤血球低温保存モデルのシミュレーション解析とメタボローム測定による検証2008
- Author(s)
  西野泰子, 谷内江綾子, 平山明由, 曽我朋義, 末松誠, 冨田勝
- Organizer
  第3回メタボロームシンポジウム
- Place of Presentation
  鶴岡市
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 細胞における代謝の時空間シミュレーション2008
- Author(s)
  谷内江綾子川原仁志野田茂穂須永泰弘大日向大地横田秀夫末松誠
- Organizer
  BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 網羅的代謝解析により強化された肝細胞代謝モデルの開発と応用2008
- Author(s)
  谷内江綾子, 藤木夏子, 福田亮, 末松誠
- Organizer
  バイオスーパーコンピューティングシンポジウム2008
- Place of Presentation
  東京
- Year and Date
  2008-12-25
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 細胞シミュレーションとメタボローム解析による実証2008
- Author(s)
  谷内江綾子
- Organizer
  第291回CBI学会研究講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] 赤血球代謝モデルの応用と4D細胞シミュレーションへの拡張2008
- Author(s)
  谷内江綾子, 川原仁志, 西野泰子, 須永泰弘, 野田茂穂, 大日向大地, 横田秀夫,末松誠
- Organizer
  バイオスーパーコンピューティングシンポジウム2008
- Place of Presentation
  東京
- Year and Date
  2008-12-25
- Data Source
  KAKENHI-PROJECT-20790237
[Presentation] Simulation and metabolome analysis of human red blood cells during storage in MAP medium at 4℃2008
- Author(s)
  Taiko Nishino, Ayako Yachie-Kinoshita, Makoto Suematsu and Masaru Tomita
- Organizer
  The 9th International Conference on Systems Biology
- Place of Presentation
  Gothenburg, Sweden
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-20790237

1. MINAMISHIMA Yoji Andrew (20593966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KUBO Akiko (50455573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HISHIKI Takako (10338022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yachie Ayako 谷内江 綾子

YACHIE Ayako 谷内江 綾子

Research Projects

Research Products

Co-Researchers

New concept for treatment of iscgemia/reperfusion injuries brought by metabolomics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prediction of metabolic dynamics in human erythrocytes based on a large-scale mathematical model and its verification by metabolome analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hypotaurine is an energy-saving hepatoprotective compound against ischemia-reperfusion injury of the rat liver.2010

Author(s)

Journal Title

Data Source

[Journal Article] Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry Antioxid2010

Author(s)

Journal Title

Data Source

[Journal Article] T-state stabilization of hemoglobin by nitric oxide to form a-nitrosyl heme causes constitutive release of ATP from human erythrocytes2010

Author(s)

Journal Title

Data Source

[Journal Article] A Metabolic Model of Human Erythrocytes: Practical Application of the E-Cell Simulation Environment2010

Author(s)

Journal Title

Data Source

[Journal Article] Hypotaurine is an energy-saving hepatoprotective compound against ischemia-reperfusion injury of the rat liver2010

Author(s)

Journal Title

Data Source

[Journal Article] T-state stabilization of hemoglobin by nitric oxide to form alpha-nitrosyl heme causes constitutive release of ATP from human erythrocytes.2010

Author(s)

Journal Title

Data Source

[Journal Article] In silico modeling and metabolome analysis of long-stored erythrocytes to improve blood storage methods2009

Author(s)

Journal Title

Data Source

[Journal Article] E-Cell systemによるヒト赤血球代謝シミュレーションの展開2009

Author(s)

Journal Title

Data Source

[Journal Article] In silico modeling and metabolome analysis of long-stored erythrocytes to improve blood storage methods.2009

Author(s)

Journal Title

Data Source

[Journal Article] E-Cell systemによるヒト赤血球代謝シミュレーションの展開2009

Author(s)

Journal Title

Data Source

[Presentation] Mathematical modeling of preserved red blood cells towards improvement of blood storage2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] シミュレーションとメタボローム解析による新規血液保存法の開発2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 赤血球代謝シミュレーションとメタボローム解析による新規血液保存法の開発2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規血液保存法の開発に向けた保存赤血球シミュレーションとメタボローム解析」2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 網羅的代謝解析により強化された肝細胞代謝モデルの開発と応用2008

Author(s)

Organizer

Yachie Ayako 谷内江綾子

YACHIE Ayako 谷内江綾子