YATSUGA SHUICHI 八ツ賀秀一

… Alternative Names

YATSUGA Shuichi 八ツ賀秀一

Less

Researcher Number	10454919
Other IDs
Affiliation (Current)	2025: 福岡大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2020: 久留米大学, 医学部, 講師 2013 – 2016: 久留米大学, 医学部, 助教 2015: 久留米大学, 医学部小児科, 助教 2008: 久留米大, 医学部, 助教 2007: KURUME UNIVERSITY, medical department, assistant
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator バイオマーカー / FGF21 / GDF15 / ミトコンドリア病 / 交絡因子 / NMDAS / JMDRS Except Principal Investigator MELAS / 電子伝達系酵素欠損 / ミトコンドリア病 … More / メタボローム解析 / 高乳酸血症 / GDF15 / バイオマーカー / ミトコンドリア脳筋症 / 治療薬開発 / メタボリック症候群 / 治療効果判定のバイオマーカー / 病勢のバイオマーカー / 診断バイオマーカー / 原発性肝硬変 / 自己免疫性肝炎 / インフルエンザ脳症 / 糖尿病 / ミトコンドリア機能不全 / サロゲートマーカー / 臨床性能試験 / サイトカイン / 特異度 / 感度 / 診断薬 / energy crisis / ragged red fiber / respiratory chain enzyme defect / point mutation / mitohondrial gene / nuclear gene / mitochondrial myopathy / ミトコンドリア脳菌 / エネルギー不全 / ragged-red fibers / 点変異 / ミトコンドリア遺伝子 / 核遺伝子 / ミトコンドリア脳筋 / 創薬研究 / 評価指標 / 医薬品開発 / 診断システム / 効果判定 / 薬物治療 / 重症度分類 / 体外診断薬開発 / 診断アルゴリズム / 感度・特異度 / 遺伝子相互作用 / A3243G変異 / 電子伝達系酵素活性 / 分子集合 / シナジー効果 / 核DNA / ミトコンドリアDNA Less

Basic research of GDF15 therapy for mitochondrial diseases/metabolic syndrome
- Principal Investigator
  
  Koga Yasutoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
A study of confounding factors in novel biomarkers GDF15 and FGF21 for mitochondrial disordersPrincipal Investigator
- Principal Investigator
  
  Yatsuga Shuichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
Development of diagnostic biomarker of mitochondrial disorders
- Principal Investigator
  
  KOGA Yasutoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
Does serum FGF21 determine severity for mitochondrial disorders?Principal Investigator
- Principal Investigator
  
  Yatsuga Shuichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
ミトコンドリア・核ゲノム間ネットワークの解明Principal Investigator
- Principal Investigator
  
  八ツ賀秀一
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
電子伝達系酵素アッセンブリーにおける核およびミトコンドリア多型のシナジー効果
- Principal Investigator
  
  KOGA Yasutoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
Analysis of mitochondria-nucleus inter-genetic network
- Principal Investigator
  
  KOGA Yasutoshi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University

All 2020 2019 2018 2017 2016 2015 2014 2013 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Growth Differentiation Factor 15 as a useful biomarker of heart failure in young patients with unrepaired congenital heart disease of left to right shunt2020
- Author(s)
  Kagiyama Y, Yatsuga S, Kinoshita M, Koteda Y, Kishimoto S, Koga Y, Suda K.
- Journal Title
  
  J Cardiol.
  
  Volume: 75 Issue: 6 Pages: 697-701
- DOI
  10.1016/j.jjcc.2019.12.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07892
[Journal Article] GDF-15, a mitochondrial disease biomarker, is associated with the severity of multiple sclerosis2019
- Author(s)
  Nohara S, Ishii A, Yamamoto F, Yanagiha K, Moriyama T, Tozaka N, Miyake Z, Yatsuga S, Koga Y, Hosaka T, Terada M, Yamaguchi T, Aizawa S, Mamada N, Tsuji H, Tomidokoro Y, Nakamagoe K, Ishii K, Watanabe M, Tamaoka A
- Journal Title
  
  Journal of the neurological sciences
  
  Volume: 405 Pages: 116429-116429
- DOI
  10.1016/j.jns.2019.116429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07892, KAKENHI-PROJECT-17K15887
[Journal Article] Temple syndrome diagnosed in an adult patient with clinical autism spectrum disorder2018
- Author(s)
  Kimura T, Kagami M, Matsubara K, Yatsuga S, Mukasa R, Yatsuga C, Matsumoto T, Koga Y.
- Journal Title
  
  Clinical Case Reports
  
  Volume: 7 Issue: 1 Pages: 15-18
- DOI
  10.1002/ccr3.1895
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07892
[Journal Article] mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression2017
- Author(s)
  Khan NA, Nikkanen J, Yatsuga S, Jackson C, Wang L, Pradhan S, Kivel R, Pessia A, Velagapudi V, Suomalainen A
- Journal Title
  
  Cell Metab
  
  Volume: 26 Issue: 2 Pages: 419-428
- DOI
  10.1016/j.cmet.2017.07.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10003
[Journal Article] Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders.2015
- Author(s)
  Yatsuga S, Fujita Y, Ishii A, Fukumoto Y, Arahata H, Kakuma T, Kojima T, Ito M, Tanaka M, Saiki R, Koga Y.
- Journal Title
  
  Ann Neurol
  
  Volume: 78 Issue: 5 Pages: 814-823
- DOI
  10.1002/ana.24506
- NAID
  120007135881
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461100, KAKENHI-PROJECT-25461571, KAKENHI-PROJECT-26670481, KAKENHI-PROJECT-25860891, KAKENHI-PROJECT-25242062
[Journal Article] New TRPM6 mutation and management of hypomagnesaemia with secondary hypocalcaemia.2015
- Author(s)
  Katayama K, Povalko N, Yatsuga S, Nishioka J, Kakuma T, Matsuishi T, Koga Y.
- Journal Title
  
  Brain Dev.
  
  Volume: 37 Issue: 3 Pages: 292-298
- DOI
  10.1016/j.braindev.2014.06.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461571
[Journal Article] (2014) GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases2015
- Author(s)
  Yasunori Fujita, Masafumi Ito, Toshio Kojima, Shuichi Yatsuga, Yasutoshi Koga, Masashi Tanaka
- Journal Title
  
  Mitochondrion
  
  Volume: 20 Pages: 34-42
- DOI
  10.1016/j.mito.2014.10.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25242062, KAKENHI-PROJECT-25461571, KAKENHI-PROJECT-26350922, KAKENHI-PROJECT-26670342, KAKENHI-PROJECT-26670481, KAKENHI-PROJECT-25860891
[Journal Article] Genome-wide copy number analysis and systematic mutation screening in 58 patients with hypogonadotropic hypogonadism2014
- Author(s)
  Izumi Y, Suzuki E, Kanzaki S, Yatsuga S, Kinjo S, Igarashi M, Maruyama T, Sano S, Horikawa R, Sato N, Nakabayashi K, Hata K, Umezawa A, Ogata T, Yoshimura Y, Fukami M
- Journal Title
  
  Fertil Steril
  
  Volume: 102(4) Issue: 4 Pages: 1130-1136
- DOI
  10.1016/j.fertnstert.2014.06.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-24390381, KAKENHI-PROJECT-24591512, KAKENHI-PROJECT-25670706, KAKENHI-PROJECT-25860891, KAKENHI-PROJECT-26293224, KAKENHI-PROJECT-26860837
[Journal Article] ミトコンドリア病の新しいバイオマーカーFGF212014
- Author(s)
  八ツ賀秀一、古賀靖敏
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 32 Pages: 704-705
- Data Source
  KAKENHI-PROJECT-25860891
[Journal Article] Glycogenic hepatopathy and non-alcoholic fatty liver disease in type 1 diabetes patients2013
- Author(s)
  Saikusa M, Yatsuga S, Tonan T, Koga Y
- Journal Title
  
  Pediatrics International
  
  Volume: Dec;55(6) Issue: 6 Pages: 806-807
- DOI
  10.1111/ped.12235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860891
[Journal Article] De novo frameshift mutation in fibroblast growth factor 8 in a male patient with gonadotropin deficiency2013
- Author(s)
  Suzuki E, Yatsuga S, Igarashi M, Miyado M, Nakabayashi K, Hayashi K, Hata K, Umezawa A, Yamada G, Ogata T, Fukami M*
- Journal Title
  
  Horm Res Paediatr ,
  
  Volume: 81 Issue: 2 Pages: 139-144
- DOI
  10.1159/000355380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-24790303, KAKENHI-PROJECT-24791103, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-25860891
[Journal Article] Effect of L-arginine on synaptosomal mitochondrial functio2008
- Author(s)
  Hirata K, Akita Y, Povalko N, Nishioka J, Yatsuga S, Matsuishi T, Koga Y
- Journal Title
  
  Brain and Dev. 30
  
  Pages: 238-245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] Inappropriate intracranial hemodynamics in the natural course of MELAS.2008
- Author(s)
  Nishioka J, Akita Y, Yatsuga S, Katayama K, Koga Y
- Journal Title
  
  Brain and Dev. 30
  
  Pages: 100-105
- NAID
  10025169185
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] MELAS and L-arginine therapy.2007
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N,Katayama K, Matsuishi T
- Journal Title
  
  Mitochondrion 7
  
  Pages: 133-139
- NAID
  10027697233
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] ミトコンドリア異常症、けいれん・意識障害を起こす患者の治療・管理のポイント2006
- Author(s)
  古賀靖敏, 八ツ賀秀一
- Journal Title
  
  小児内科 38(2)
  
  Pages: 443-447
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] Mitochondrial tRNA gene mutations in patients having mitochondrial disease with lactic acidosis.2006
- Author(s)
  Ueki I, Koga Y, Povalko N, Akita Y, Nishioka J, Yatsuga S, Fukiyama R, Matsuishi T
- Journal Title
  
  Mitochondrion 6
  
  Pages: 39-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] Endothelial dysfunction in MELAS was improved by L-arginine supplementation.2006
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Fukiyama R, Ishii M, Matsuishi T
- Journal Title
  
  Neurology 66
  
  Pages: 1766-1769
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] ミトコンドリア異常症,けいれん・意識障害を起こす疾患の治療・管理のポイント2006
- Author(s)
  古賀靖敏, 八ツ賀秀一
- Journal Title
  
  小児内科 38
  
  Pages: 443-447
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] L-arginine improves the symptoms of stroke-like episodes in MELAS.2005
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Tanabe Y, Fujimoto S, _Matsuis
- Journal Title
  
  Neurology 64
  
  Pages: 710-712
- Data Source
  KAKENHI-PROJECT-16390308
[Journal Article] Fujimoto S, Matsuishi T: L-arginine improves the symptoms of stroke? like episodes in MELAS.2005
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Tanabe Y
- Journal Title
  
  Neurology 64(4)
  
  Pages: 710-712
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] ミトコンドリア病のバイオマーカー2018
- Author(s)
  八ツ賀秀一、古賀靖敏
- Organizer
  日本小児神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10003
[Presentation] ミトコンドリア病のバイオマーカーGDF15は新生児期に高値となる2018
- Author(s)
  八ツ賀秀一、木下正啓、古賀靖敏
- Organizer
  日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-16K10003
[Presentation] ミトコンドリア病のバイオマーカー2018
- Author(s)
  八ツ賀秀一
- Organizer
  第60回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07892
[Presentation] ミトコンドリア病とALSにおける髄液と血液のGDF15の関連2017
- Author(s)
  八ツ賀秀一
- Organizer
  第17回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-16K10003
[Presentation] Elevation of serum fibroblast growth factor 21 in congenital hypothyroidism2016
- Author(s)
  Shuichi Yatsuga
- Organizer
  ESPE
- Place of Presentation
  Le Palais des Congres de Paris (Paris, France)
- Year and Date
  2016-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10003
[Presentation] 小児内分泌疾患におけるFGF21の検討2016
- Author(s)
  八ツ賀秀一、佐々木孝子、西岡淳子、牛嶋規久美、喜多村美幸、古賀靖敏
- Organizer
  日本内分泌学会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16K10003
[Presentation] Serum GDF15 levels in diseases similar to mitochondrial disorders2016
- Author(s)
  Shuichi Yatsuga, Akiko Ishii, Miyuki Kitamura, Yasutoshi Koga
- Organizer
  ASMRM
- Place of Presentation
  TKP Garden City Shinagawa (Tokyo, Japan)
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10003
[Presentation] GDF15 as the most reliable biomarker for mitochondrial disorders2016
- Author(s)
  Yasutoshi Koga, Shuichi Yatsuga, Akiko Ishii, Tatsuyuki Kakuma, Masashi Tanaka
- Organizer
  Biomarker Summit 2016
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2016-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] GDF15はミトコンドリア病の新規バイオマーカーとして有用2016
- Author(s)
  八ツ賀秀一
- Organizer
  第8回福岡県医学会総会
- Place of Presentation
  福岡県医師会館（福岡市）
- Year and Date
  2016-02-07
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF15 はミトコンドリア病の新規バイオマーカーとして有用2016
- Author(s)
  八ツ賀秀一、石井亜紀子、藤田泰典、小島俊男、伊藤雅史、田中雅嗣、角間辰之、古賀靖敏
- Organizer
  第8回福岡県医学会総会
- Place of Presentation
  福岡県医師会館（福岡市）
- Year and Date
  2016-02-07
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] ミトコンドリア病の新規バイオマーカー2016
- Author(s)
  八ツ賀秀一
- Organizer
  第126回筑後地区内分泌代謝疾患症例検討会
- Place of Presentation
  久留米医師会館（久留米市）
- Year and Date
  2016-02-04
- Invited
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Serum GDF15 levels in diseases with similarity to mitochondrial disorders2016
- Author(s)
  Shuichi Yatsuga, Akiko Ishii, Miyuki Kitamura, Yasutoshi Koga
- Organizer
  UMDF
- Place of Presentation
  DoubleTree by Hilton (Seattle, USA)
- Year and Date
  2016-06-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10003
[Presentation] ミトコンドリア病類縁疾患におけるGDF15・FGF21の検討2015
- Author(s)
  八ツ賀秀一、石井亜紀子、喜多村美幸、佐々木孝子、牛嶋規久美、齊木玲央、古賀靖敏
- Organizer
  第15回日本ミトコンドリア学会年会
- Place of Presentation
  福井県国際交流会館（福井市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] GDF15 is a novel biomarker of mitochondrial diseases2015
- Author(s)
  Shuichi Yatsuga, Akiko Ishii, Yoshihiro Fukumoto, Hajime Arahata, Tatsuyuki Kakuma, Yasutoshi Koga
- Organizer
  Society for Inherited Metabolic Disorders 2015
- Place of Presentation
  Grand America Hotel (Salt Lake City)
- Year and Date
  2015-03-29
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] 低身長児における血清亜鉛の検討2015
- Author(s)
  西岡淳子、佐々木孝子、八ツ賀秀一、牛嶋規久美、片山幸樹、古賀靖敏、松石豊次郎
- Organizer
  第483回日本小児科学会福岡地方会例会
- Place of Presentation
  久留米大学筑水会館（福岡県久留米市）
- Year and Date
  2015-02-14
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF-15とFGF-21はミトコンドリア病の重症度と相関する2015
- Author(s)
  八ツ賀秀一、角間辰之、古賀靖敏
- Organizer
  第57回日本小児神経学会学術集会
- Place of Presentation
  帝国ホテル大阪（大阪市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] 低ゴナドトロピン性性腺機能低下症58例の網羅的遺伝子解析2015
- Author(s)
  鈴木江莉奈、泉陽子、神崎晋、八ツ賀秀一、金城さおり、五十嵐麻希、中林一彦、梅澤明弘、秦健一郎、緒方勤、深見真紀
- Organizer
  第19回日本生殖内分泌学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-01-10
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF15 (growth differentiation factor 15) is the new biomarker for muscle-related mitochondrial diseases2015
- Author(s)
  Shuichi Yatsuga, Akiko Ishii, Hajime Arahata, Yoshihiro Fukumoto, Masashi Tanaka, Yasutoshi Koga
- Organizer
  The 67th American Academy of Neurology Annual Meeting
- Place of Presentation
  Washington, U.S.A.
- Year and Date
  2015-04-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] GDF15 as a useful biomarker for mitochondrial disorders2015
- Author(s)
  Shuichi Yatsuga
- Organizer
  Molecular Mitochondria - Joint Seminar of Young Finnish-Japanese Mitoscientists
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF15 is a novel biomarker of mitochondrial diseases2015
- Author(s)
  Shuichi Yatsuga, Akiko Ishii, Yoshihiro Fukumoto, Hajime Arahata, Tatsuyuki Kakuma, Yasutoshi Koga
- Organizer
  Society for Inherited Metabolic Disorders 2015
- Place of Presentation
  Grand America Hotel (Salt Lake City, USA)
- Year and Date
  2015-03-29
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Development of biomarkers for mitochondrial disorders2015
- Author(s)
  Shuichi Yatsuga
- Organizer
  熊本大学大学院セミナー
- Place of Presentation
  熊本大学
- Year and Date
  2015-12-16
- Invited
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Development of biomarkers for mitochondrial disorders2015
- Author(s)
  Shuichi Yatsuga
- Organizer
  Molecular Mitochondria - Joint Seminar of Young Finnish-Japanese Mitoscientists
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2015-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF-15：最も信頼できるミトコンドリア病のバイオマーカー2015
- Author(s)
  八ツ賀秀一、石井亜紀子、角間辰之、古賀靖敏
- Organizer
  第57回日本小児神経学会学術集会
- Place of Presentation
  帝国ホテル大阪（大阪市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 健康な日本人におけるFGF21の検討2015
- Author(s)
  八ツ賀秀一、佐々木孝子、西岡淳子、片山幸樹、牛嶋規久美、古賀靖敏
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京(東京都)
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] ミトコンドリア病類縁疾患におけるGDF15・FGF21の検討2015
- Author(s)
  八ツ賀秀一、石井亜紀子、喜多村美幸、佐々木孝子、牛嶋規久美、齊木玲央、古賀靖敏
- Organizer
  第15回日本ミトコンドリア学会年会
- Place of Presentation
  福井県国際交流会館（福井県福井市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 健康な日本人におけるFGF21の検討2015
- Author(s)
  八ツ賀秀一、佐々木孝子、西岡淳子、片山幸樹、牛嶋規久美、古賀靖敏
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京(東京都）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF-15：最も信頼できるミトコンドリア病のバイオマーカー2015
- Author(s)
  八ツ賀秀一、石井亜紀子、角間辰之、古賀靖敏
- Organizer
  第57回日本小児神経学会学術集会
- Place of Presentation
  帝国ホテル大阪（大阪市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] GDF-15とFGF-21はミトコンドリア病の重症度と相関する2015
- Author(s)
  八ツ賀秀一、角間辰之、古賀靖敏
- Organizer
  第57回日本小児神経学会学術集会
- Place of Presentation
  帝国ホテル大阪（大阪市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF-15&FGF-21：ミトコンドリア病の新規バイオマーカー2014
- Author(s)
  八ツ賀秀一, 石井亜紀子, 藤田泰典, 小島俊男, 伊藤雅史, 田中雅嗣, 角間辰之, 古賀靖敏
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九州大学医学部百年講堂（福岡県福岡市）
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] ピルビン酸ナトリウムを開始したミトコンドリア呼吸鎖異常症の6か月男児2014
- Author(s)
  金城さおり、豊浦麻記子、吉年俊文、喜久山至、小濱守安、閑野将行、源川隆一、八ツ賀秀一、古賀靖敏
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] 保健所と医療の連携により高度肥満から虐待が疑われ迅速に対応できた一例2014
- Author(s)
  八ツ賀秀一、家村明子、佐々木孝子、西岡淳子、片山幸樹、牛島規久美、古賀靖敏、松石豊次郎
- Organizer
  第482回日本小児科学会福岡地方会例会
- Place of Presentation
  福岡大学メディカルホール（福岡県福岡市）
- Year and Date
  2014-12-13
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 複合型下垂体ホルモン不全症患者におけるWDR11スプライスサイト変異の同定2014
- Author(s)
  泉陽子、西岡淳子、八ツ賀秀一、鈴木江莉奈、佐野伸一朗、中林一彦、梅澤明弘、秦健一郎、緒方勤、深見真紀
- Organizer
  第48回日本小児内分泌学会学術集会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 内分泌専門外来開設1年間における経過報告2014
- Author(s)
  西奈津子、力武典子、八ツ賀秀一
- Organizer
  第69回日本小児科学会佐賀地方会例会
- Place of Presentation
  佐賀大学小講堂（佐賀県佐賀市）
- Year and Date
  2014-04-05
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 健康日本人の血漿FGF21値の検討2014
- Author(s)
  八ツ賀秀一、佐々木孝子、古賀靖敏
- Organizer
  第48回日本小児内分泌学会学術集会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] DAX1過剰を認めた46,Y,add(X)(p22.1) DSDの一例2014
- Author(s)
  佐々木孝子、泉陽子、深見真紀、八ツ賀秀一、古賀靖敏
- Organizer
  第117回日本小児科学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2014-04-12
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Clinical and Molecular Characterization of the Largest Family with Congenital Hypothyroidism due to a PAX8 Mutation2014
- Author(s)
  Kiyomi Abe, Satoshi Narumi, Junko Nishioka, Shuichi Yatsuga, Tateo Kuno, Kaori Kameyama, Tomonobu Hasegawa
- Organizer
  ENDO 2014
- Place of Presentation
  McCormick Place (Chicago, USA)
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Growth differentiation factor 15 and fibroblast growth factor 21: novel biomarkers for mitochondrial diseases2014
- Author(s)
  Shuichi YATSUGA, Yasutoshi KOGA
- Organizer
  EuroMIT 2014
- Place of Presentation
  Tampere hall (Tampere, Finland)
- Year and Date
  2014-06-16
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF15はミトコンドリア病の新しいバイオマーカーになる2014
- Author(s)
  八ツ賀秀一、古賀靖敏
- Organizer
  第56回日本先天代謝異常学会
- Place of Presentation
  江陽グランドホテル（宮城県仙台市）
- Year and Date
  2014-11-14
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Prader-Willi症候群：双子の思春期早発例2014
- Author(s)
  八ツ賀秀一、牛島高介、古賀靖敏
- Organizer
  第37回日本小児遺伝学会学術集会
- Place of Presentation
  名古屋市立大学会議室（愛知県名古屋市）
- Year and Date
  2014-04-10
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Growth differentiation factor 15 and fibroblast growth factor 21: novel biomarkers for mitochondrial diseases2014
- Author(s)
  Shuichi Yatsuga, Yasutoshi Koga
- Organizer
  EuroMIT 2014
- Place of Presentation
  Tampere Hall (Tampere, Finland)
- Year and Date
  2014-06-16
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] 血漿FGF21は筋症状を伴うミトコンドリア病のバイオマーカーになる2014
- Author(s)
  八ツ賀秀一、古賀靖敏
- Organizer
  第56回日本小児神経学会学術集会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Growth Differentiation Factor 15 and Fibroblast Growth Factor 21: Novel Biomarkers for Mitochondrial Diseases2014
- Author(s)
  Shuichi Yatsuga, Yasutoshi Koga
- Organizer
  53rd Annual ESPE Meeting
- Place of Presentation
  Convention Centre Dublin (Dublin, Ireland)
- Year and Date
  2014-09-18
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] Growth differentiation factor 15 and fibroblast growth factor 21: novel biomarkers for mitochondrial diseases2014
- Author(s)
  Shuichi YATSUGA, Yasutoshi KOGA
- Organizer
  53rd Annual ESPE Meeting
- Place of Presentation
  Convention Centre Dublin (Dublin, Ireland)
- Year and Date
  2014-09-18
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 神経性食思不振症に甲状腺機能亢進を合併した１例2014
- Author(s)
  佐々木孝子、八ツ賀秀一、西岡淳子、古賀靖敏
- Organizer
  第48回日本小児内分泌学会学術集会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] ピルビン酸ナトリウムを開始したミトコンドリア呼吸鎖異常症の6か月男児2014
- Author(s)
  金城さおり、豊浦麻記子、吉年俊文、喜久山至、小濱守安、閑野将行、源川隆一、八ツ賀秀一、古賀靖敏
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] GDF-15 ＆ FGF-21：ミトコンドリア病の新規バイオマーカー2014
- Author(s)
  八ツ賀秀一、石井亜紀子、藤田泰典、小島俊男、伊藤雅史、田中雅嗣、角間辰之、古賀靖敏
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九州大学医学部百年講堂（福岡県福岡市）
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Growth differentiation factor 15 and fibroblast growth factor 21: novel biomarkers for mitochondrial diseases2014
- Author(s)
  Shuichi YATSUGA, Yasutoshi KOGA
- Organizer
  Mitochondrial Medicine 2014
- Place of Presentation
  Sheraton Station Square Hotel (Pittsburgh, USA)
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Growth differentiation factor 15 and fibroblast growth factor 21: novel biomarkers for mitochondrial diseases2014
- Author(s)
  Shuichi Yatsuga, Yasutoshi Koga
- Organizer
  Mitochondrial Medicine 2014
- Place of Presentation
  Sheraton Station Square Hotel (Pittsburgh, USA)
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] 健康日本人の血漿FGF21値の検討2014
- Author(s)
  八ツ賀秀一、佐々木孝子、古賀靖敏
- Organizer
  第48回日本小児内分泌学会学術集会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] GDF15はミトコンドリア病の新しいバイオマーカーになる2014
- Author(s)
  八ツ賀秀一、古賀靖敏
- Organizer
  第56回日本先天代謝異常学会
- Place of Presentation
  江陽グランドホテル（宮城県仙台市）
- Year and Date
  2014-11-14
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] 血漿FGF21は筋症状を伴うミトコンドリア病のバイオマーカーになる2014
- Author(s)
  八ツ賀秀一、古賀靖敏
- Organizer
  第56回日本小児神経学会学術集会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25461571
[Presentation] FGF21：疾患特異的バイオマーカーの探索2013
- Author(s)
  八ツ賀秀一、古賀靖敏
- Organizer
  第47回小児内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 正常身長の両親を有するGH単独欠損症II型の1例-GH1遺伝子検索の有用性-2013
- Author(s)
  片山幸樹、長崎啓祐、深見真紀、八ツ賀秀一、西岡淳子、古賀靖敏
- Organizer
  第47回小児内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 4世代にわたる世界最大の新規PAX8変異陽性甲状腺機能低下症家系：甲状腺表現型の多様性2013
- Author(s)
  阿部清美、西岡淳子、八ツ賀秀一、久野建夫、鳴海覚志、長谷川奉延
- Organizer
  第56回日本甲状腺学会学術集会
- Place of Presentation
  和歌山市
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Follow-up study: FGF21 is a new biomarker to diagnose muscle-related mitochondrial diseases in Japanese patients2013
- Author(s)
  Yatsuga S、Koga Y
- Organizer
  第13回日本ミトコンドリア学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 4世代にわたる世界最大のPAX8変異要請甲状腺機能低下症家系ー甲状腺表現型の多様性ー2013
- Author(s)
  佐々木孝子、阿部清美、鳴海覚志、長谷川奉延、西岡淳子、片山幸樹、八ツ賀秀一、古賀靖敏、久野建夫
- Organizer
  第47回小児内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Fibroblast growth factor 21 (FGF21): A biomarker of mitochondrial diseases but not endocrine diseases2013
- Author(s)
  Yatsuga S, Koga Y
- Organizer
  52th annual European Society of Pediatric Endocrinology meeting
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 血糖コントロール不良1型糖尿病のglycogenic hepatopathyはMRIで診断可能か？2013
- Author(s)
  七種護、八ツ賀秀一、片山幸樹、西岡淳子、古賀靖敏、松石豊次郎
- Organizer
  第116回日本小児科学会学術集会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] Kallmann 症候群患者におけるFGF8 フレームシフト変異の同定2013
- Author(s)
  鈴木江莉奈、八ツ賀秀一、五十嵐麻希、宮戸真美、中林一彦、秦健一郎、緒方勤、深見真紀
- Organizer
  第47回小児内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860891
[Presentation] 1カ月健診で発見した17α-水酸化酵素欠損症の1例2007
- Author(s)
  八ツ賀秀一
- Organizer
  内分泌・骨疾患研究会e-Conference
- Place of Presentation
  久留米
- Year and Date
  2007-06-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] L-arginine cure the stroke-like episodes in MELAS by Improving endothelial function.2007
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Katayama K, Matsuishi T, Povalko N.
- Organizer
  The 4th Annual Meeting of Asian Society for Mitochondrial Research and Medicine.
- Place of Presentation
  Seoul, Korea
- Year and Date
  2007-02-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] MELASの自然歴,日本の全国調査と文献との比較2007
- Author(s)
  八ツ賀秀一
- Organizer
  第110回日本小児科学会
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] Study design in investigator-initiated phase III clinical trial of L-arginine on MELAS.2007
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Katayama K, Matsuishi T.
- Organizer
  11th Congress of the federation of neurological societies.
- Place of Presentation
  Brussels, Belgium
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] Incience and natural course of MELAS in Japan-Japanese cohort study-.2007
- Author(s)
  Koga Y, Yatsuga S, Akita Y, Nishioka J, Katayama K, Povalko N, Matsuishi T.
- Organizer
  48th annual meeting of the European society for pediatric research.
- Place of Presentation
  Prague, Czech
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] MELAS and L-arginine therapy.2006
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Katayama K, Matsuishi T.
- Organizer
  Workshop sponsored by the Research Grant(17A-10) for Nervous and Mental Disorders. The Front Line of Therapy for Mitochondrial Myopathy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2006-10-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] MELAS and L-arginine therapy.2006
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N.
- Organizer
  11th International Congress on Neur omuscular Diseases.
- Place of Presentation
  Istanbul, Turkey
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] L-arginine therapy in MELAS.2005
- Author(s)
  Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Matsuishi T.
- Organizer
  18th World Congress of Neurology.
- Place of Presentation
  Sydney, Australia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390308
[Presentation] 重症心身障害者施設でデスモプレシン製剤を点鼻から経口へ切り替えた口渇の訴えのない1症例
- Author(s)
  八ツ賀秀一、古賀靖敏、松石豊次郎、大滝悦生、松尾勇作、稲田浩子、本廣孝
- Organizer
  第477回日本小児科学会福岡地方会
- Place of Presentation
  福岡県久留米市
- Data Source
  KAKENHI-PROJECT-25860891

1. KOGA Yasutoshi (00225400)

# of Collaborated Projects: 6 results

# of Collaborated Products: 67 results
2. NISHIOKA Junko (00449919)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
3. AKITA Yukihiro (20330821)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. KITAMURA Miyuki (70772911)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. SASAKI Takako (80726547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. USHIJIMA Kikumi (00750829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. SAIKI Reo (40726577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. HIRATA Koji (50360293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MAJIMA Hideyuki (60165701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OGATA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. FUKAMI Maki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. FUKUMOTO Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 田中雅嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YATSUGA SHUICHI 八ツ賀 秀一

YATSUGA Shuichi 八ツ賀 秀一

Research Projects

Research Products

Co-Researchers

Basic research of GDF15 therapy for mitochondrial diseases/metabolic syndrome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study of confounding factors in novel biomarkers GDF15 and FGF21 for mitochondrial disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of diagnostic biomarker of mitochondrial disorders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Does serum FGF21 determine severity for mitochondrial disorders?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ミトコンドリア・核ゲノム間ネットワークの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

電子伝達系酵素アッセンブリーにおける核およびミトコンドリア多型のシナジー効果

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of mitochondria-nucleus inter-genetic network

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Growth Differentiation Factor 15 as a useful biomarker of heart failure in young patients with unrepaired congenital heart disease of left to right shunt2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GDF-15, a mitochondrial disease biomarker, is associated with the severity of multiple sclerosis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Temple syndrome diagnosed in an adult patient with clinical autism spectrum disorder2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] New TRPM6 mutation and management of hypomagnesaemia with secondary hypocalcaemia.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (2014) GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases2015

Author(s)

YATSUGA SHUICHI 八ツ賀秀一

YATSUGA Shuichi 八ツ賀秀一