HATAKEYAMA Hiromitsu 畠山博充

Researcher Number	10455652
Other IDs
External Links
Affiliation *help	2017 – 2018 : 横浜市立大学, 附属市民総合医療センター, 准教授 2011 – 2016 : 北海道大学, 大学病院, 助教 2014 : 北海道大学, 北海道大学病院, 助教 2010 : 北海道大学, 病院, 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 頭頸部癌 / シグナル伝達 / リガンド / microRNA / EGFR / ゲノム / 上皮成長因子受容体（EGFR) / p53経路 / プロテオーム / RB / heterogeneity / バイオインフォマティクス … More Except Principal Investigator … More

頭頸部癌heterogeneityを引き起こす微小環境のオーム解析Principal InvestigatorOngoing
- Principal Investigator
  
  畠山博充
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yokohama City University
Elucidation of signaling network of head and neck cancer by bioinformatics approachPrincipal Investigator
- Principal Investigator
  
  Hatakeyama Hiromitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hokkaido University
Gene mutation and 3D-conformation of proteins related to EGFR pathway in head and neck cancer
- Principal Investigator
  
  HOMMA Akihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hokkaido University
Network of signaling pathway of head and neck cancerPrincipal Investigator
- Principal Investigator
  
  HATAKEYAMA Hiromitsu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hokkaido University
Identification of markers for overexpression of EGFR in head and neck cancer using genomics and proteomics
- Principal Investigator
  
  HOMMA Akihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hokkaido University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Expression of p53, p16, cyclin D1, epidermal growth factor receptor and Notch1 in patients with temporal bone squamous cell carcinoma.2017
- Author(s)
  Morita S, Nakamaru Y, Homma A, Yasukawa S, Hatakeyama H, Sakashita T, Kano S, Fukuda A, Fukuda S
- Journal Title
  
  Int J Clin Oncol.
  
  Volume : 22 Issue : 1 Pages : 181-189
- Publisher
  Springer
- DOI
  10.1007/s10147-016-1026-5
- ISSN
  1341-9625
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462591
[Journal Article] The outcomes of surgery and chemoradiotherapy for temporal bone cancer.2016
- Author(s)
  Morita S, Homma A, Nakamaru Y, Sakashita T, Hatakeyama H, Kano S, Fukuda A, Fukuda S.
- Journal Title
  
  Otology & Neurotology
  
  Volume : 37 Pages : 1174-1182
- DOI
  10.1097/mao.0000000000001152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462591
[Journal Article] Effectiveness of superselective intra-arterial chemoradiotherapy targeting retropharyngeal lymph node metastasis.2016
- Author(s)
  Suzuki T, Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Suzuki F, Fukuda S.
- Journal Title
  
  Eur Arch Otorhinolaryngol.
  
  Volume : 273 Issue : 10 Pages : 3331-3336
- Publisher
  Springer
- DOI
  10.1007/s00405-016-3933-5
- ISSN
  0937-4477
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462591, KAKENHI-PROJECT-26861353
[Journal Article] The role of prophylactic neck dissection and tumor thickness evaluation for patients with cN0 tongue squamous cell carcinoma.2016
- Author(s)
  Tsushima N, Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Kakizaki T, Suzuki T, Fukuda S.
- Journal Title
  
  Eur Arch Otorhinolaryngol.
  
  Volume : 273 Issue : 11 Pages : 3987-3992
- Publisher
  Springer
- DOI
  10.1007/s00405-016-4077-3
- ISSN
  0937-4477
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462591
[Journal Article] A retrospective study of G-tube use in Japanese patients treated with concurrent chemoradiotherapy for hypopharyngeal cancer.2016
- Author(s)
  Homma A, Hatakeyama H, Mizumachi T, Kano S, Sakashita T, Kuramoto R, Nakamaru Y, Onimaru R, Tsuchiya K, Yoshida D, Yasuda K, Shirato H, Fukuda S.
- Journal Title
  
  Plos One
  
  Volume : 11 Issue : 8 Pages : e0161734
- Publisher
  The Public Library of Science
- DOI
  10.1371/journal.pone.0161734
- Year and Date
  2016-08-24
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462591, KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Journal Article] Decreased SMAD4 expression is associated with induction of epithelial-to-mesenchymal transition and cetuximab resistance in head and neck squamous cell carcinoma.2015
- Author(s)
  Cheng H, Fertig EJ, Ozawa H, Hatakeyama H, Howard JD, Perez J, Considine M, Thakar M, Ranaweera R, Krigsfeld G, Chung CH.
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume : 16 Pages : 1252-1258
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462591
[Journal Article] Hangeshashinto improves the completion rate of chemoradiotherapy and the nutritional status in patients with head and neck cancer.2015
- Author(s)
  Hatakeyama H, Takahashi H, Oridate N, Kuramoto R, Fujiwara K, Homma A, Takeda H, Fukuda S.
- Journal Title
  
  ORL
  
  Volume : 1 Pages : 100-108
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462591
[Journal Article] Hangeshashinto Improves the Completion Rate of Chemoradiotherapy and the Nutritional Status in Patients with Head and Neck Cancer2015
- Author(s)
  Hatakeyama H, Takahashi, Oridate N, Kuramoto R, Fujiwara K., Homma A, Takeda H.,Fukuda S.
- Journal Title
  
  ORL
  
  Volume : 77 Issue : 2 Pages : 100-108
- Publisher
  Karger
- DOI
  10.1159/000381026
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462591
[Journal Article] Lymph node metastasis in the suprasternal space from thyroid papillary cancer.2015
- Author(s)
  Homma A, Hatakeyama　H, MD, Mizumachi T, Furusawa J, Kano S, Sakashita S, Fukuda S
- Journal Title
  
  Int Canc Conf J.
  
  Volume : 4 Issue : 1 Pages : 57-60
- Publisher
  Springer
- DOI
  10.1007/s13691-014-0171-9
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] Oxidative Stress Regulates IL-4 Gene Expression in Mast Cells through the Reduction of Histone Deacetylase.2015
- Author(s)
  Nakamaru, Y., Takagi, D., Homma, A., Hatakeyama, S., Fukuda, S.
- Journal Title
  
  Otolaryngol Head Neck Surg.
  
  Volume : 152 Pages : 48-52
- DOI
  10.1177/0194599814559189
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-24592574, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-24592587
[Journal Article] 中央咽頭扁平上皮癌症例に対するWeekly CDDP併用　化学放射線療法の臨床的検討2014
- Author(s)
  水町貴諭, 本間明宏, 坂下智博, 加納里志, 畠山博充, 土屋和彦, 安田耕一, 鬼丸力也, 白土博樹, 福田諭
- Journal Title
  
  頭頸部癌
  
  Volume : 40 Pages : 66-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] 頸部腫瘤摘出・生検後に中咽頭癌と診断された症例の検討2014
- Author(s)
  水町貴諭, 加納里志, 坂下智博, 畠山博充, 本間明宏, 福田諭
- Journal Title
  
  日本耳鼻咽喉科学会会報
  
  Volume : 117 Pages : 1463-1470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients. Cell Communication and Signaling.2014
- Author(s)
  Sato H, Hatanaka KC, Hatanaka Y, Hatakeyama H, Hashimoto A, Matsuno Y, Fukuda S, Sabe H.
- Journal Title
  
  Cell Commun Signal
  
  Volume : 12 Pages : 17-17
- DOI
  10.1186/1478-811x-12-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-24590674, KAKENHI-PROJECT-26462591, KAKENHI-PROJECT-23590323
[Journal Article] Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy.2014
- Author(s)
  Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Furusawa J, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Suzuki F, Fukuda S.
- Journal Title
  
  Br J Oral Maxillofac Surg
  
  Volume : 52 Issue : 4 Pages : 323-328
- Publisher
  Elsevier
- DOI
  10.1016/j.bjoms.2014.01.018
- PMID
  info:pmid/24582012
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592587, KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Journal Article] Epithelial-mesenchymal transition in human papillomavirus-positive and -negative oropharyngeal squamous cell carcinoma.2014
- Author(s)
  Hiromitsu Hatakeyama, Takatsugu Mizumachi, Tomohiro Sakashita, Satoshi Kano, Akihiro Homma, Satoshi Fukuda
- Journal Title
  
  Oncol Rep.
  
  Volume : 9 Pages : 2673-2679
- DOI
  10.3892/or.2014.3509
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462591, KAKENHI-PROJECT-26861353
[Journal Article] Early and long-term morbidity after minimally invasivetotal laryngo-pharyngo-esophagectomy with gastric pull-up reconstruction via thoracoscopy, laparoscopy and cervical incision.2014
- Author(s)
  Homma A, Nakamaru Y, Hatakeyama H, Mizumachi T, Kano S, Furusawa J, Sakashita T, Shichinohe T, Ebihara Y, Hirano S, Furukawa H, Hayashi T, Yamamoto Y, Fukuda S.
- Journal Title
  
  Eur Arch Otorhinolaryngol.
  
  Volume : Epub
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] The potential diagnostic role of the number of ultrasonographic characteristics for patients with thyroid nodules evaluated as Bethesda I-V.2014
- Author(s)
  Sakashita T, Homma A, Hatakeyama H, Mizumachi T, Kano S, Furusawa J, Iizuka S, Hoshino K, Hatanaka KC, Oba K, Fukuda S.
- Journal Title
  
  Frontiers in Oncology.
  
  Volume : 4 Pages : 261-261
- DOI
  10.3389/fonc.2014.00261
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592587, KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Journal Article] The role of initial neck dissection for patients with node-positive oropharyngeal squamous cell carcinomas2014
- Author(s)
  T. Sakashita, A. Homma, R. Hayashi, K. Kawabata, K. Yoshino, S. Iwae, Y. Hasegawa, K. Nibu, T. Kato, K. Shiga, K. Matsuura, N. Monden, M. Fuji
- Journal Title
  
  Oral Oncology
  
  Volume : 50 Issue : 7 Pages : 657-661
- Publisher
  Elsevier
- DOI
  10.1016/j.oraloncology.2014.03.003
- PMID
  info:pmid/24726547
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-24592587
[Journal Article] The incidence of late neck recurrence in N0 maxillary sinus squamous cell carcinomas after superselective intra-arterial chemoradiotherapy without prophylactic neck irradiation.2014
- Author(s)
  Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Furusawa J, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S.
- Journal Title
  
  Eur Arch Otorhinolaryngol
  
  Volume : 271 Issue : 10 Pages : 2767-2770
- Publisher
  Springer
- DOI
  10.1007/s00405-013-2806-4
- PMID
  info:pmid/24213278
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592587, KAKENHI-PROJECT-26861353
[Journal Article] Prognostic value of cyclin D1 expression in tumor-free surgical margins in head and neck squamous cell carcinomas.2013
- Author(s)
  Sakashita T, Homma A, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Oridate N, Fukuda S
- Journal Title
  
  Acta Otolaryngol
  
  Volume : 133 Issue : 9 Pages : 984-991
- Publisher
  Informa
- DOI
  10.3109/00016489.2013.795287
- PMID
  info:pmid/23692432
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791867, KAKENHI-PROJECT-23791890, KAKENHI-PROJECT-24592587
[Journal Article] Regional control after concomitant chemoradiotherapy without planned neck dissection in node-positive head and neck squamous cell carcinomas.2013
- Author(s)
  3. Sakashita T, Homma A, Oridate N, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S
- Journal Title
  
  Auris Nasus Larynx
  
  Volume : 40 Pages : 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] 喉頭癌T3症例の治療成績の検討2013
- Author(s)
  水町貴諭,折舘伸彦,本間明宏,坂下智博,加納里志,畠山博充,鈴木清護,福田諭
- Journal Title
  
  頭頸部外科
  
  Volume : 22 Pages : 317-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Regional control after concomitant chemoradiotherapy without planned neck dissection in node-positive head and neck squamous cell carcinomas2013
- Author(s)
  Sakashita T, Homma A, Oridate N, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S
- Journal Title
  
  Auris Nasus Larynx
  
  Volume : 40 Pages : 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Prognostic value of cyclin D1 expression in tumor-free surgical margins in head and neck squamous cell carcinomas2013
- Author(s)
  Sakashita T, Homma A, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Oridate N, Fukuda S
- Journal Title
  
  Acta Otolaryngol
  
  Volume : 133 Pages : 984-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Prognostic value of cyclin D1 expression in tumor-free surgical margins in head and neck squamous cell carcinomas.2013
- Author(s)
  2. Sakashita T, Homma A, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Oridate N, Fukuda S
- Journal Title
  
  Acta Otolaryngol
  
  Volume : 133 Pages : 984-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Improved survival of Japanese patients with human papillomavirus-positive oropharyngeal squamous cell carcinoma2013
- Author(s)
  Mizumachi T, Kano S, Sakashita T, Hatakeyama H, Suzuki S, Homma A, Oridate N, Fukuda S
- Journal Title
  
  Int J Clin Onco　（lEpub ahead of print）
  
  Volume : 18 Pages : 824-828
- DOI
  10.1007/s10147-012-0469-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791867, KAKENHI-PROJECT-24592587, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-22791561, KAKENHI-PROJECT-23592517
[Journal Article] Superselective intra-arterial cisplatin infusion and concomitant radiotherapy for maxillary sinus cancer.2013
- Author(s)
  Homma A, Sakashita T, Yoshida D, Onimaru R, Tsuchiya K, Suzuki F, Yasuda K, Hatakeyama H, Furusawa J, Mizumachi T, Kano S, Inamura N, Taki S, Shirato H, Fukuda S.
- Journal Title
  
  Br J Cancer
  
  Volume : 109 Issue : 12 Pages : 2980-2986
- Publisher
  Nature publishing group
- DOI
  10.1038/bjc.2013.663
- PMID
  info:pmid/24196792
- Year and Date
  2013-12-10
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791867, KAKENHI-PROJECT-24592587
[Journal Article] Rapid superselective high-dose cisplatin infusion with concomitant radiotherapy for squamous cell carcinoma of the nasal vestibule: a report of two cases.2012
- Author(s)
  Homma A, Suzuki F, Hatakeyama H, Sakashita T, Yoshida D, et al.
- Journal Title
  
  Int Canc Conf J
  
  Volume : 1 Issue : 4 Pages : 215-219
- Publisher
  Springer
- DOI
  10.1007/s13691-012-0044-z
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517, KAKENHI-PROJECT-23791867, KAKENHI-PROJECT-24592587
[Journal Article] 切除可能T3、T4上顎洞扁平上皮癌における手術の位置付けー当院における治療戦略ー.2012
- Author(s)
  本間明宏, 折舘伸彦, 鈴木清護, 鈴木章之, 畠山博充他.
- Journal Title
  
  耳鼻
  
  Volume : 58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] Combined modality therapy for laryngeal cancer with superselective intra-arterial cisplatin infusion and concomitant radiotherapy2012
- Author(s)
  Taki S, Homma A, Suzuki F, Oridate N, Hatakeyama H, Mizumachi T, Kano S, Furusawa J, Sakashita T, Inamura N, Yoshida D, Onimaru R, Shirato H, Fukuda S
- Journal Title
  
  Int J Clin Oncol
  
  Volume : 17 Pages : 441-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Improved survival of Japanese patients with human papillomavirus-positive oropharyngeal squamous cell carcinoma2012
- Author(s)
  Mizumachi T, Kano S, Sakashita T, Hatakeyama H, Suzuki S, Homma A, Oridate N, Fukuda S
- Journal Title
  
  Int J Clin Oncol
  
  Volume : 18 Pages : 824-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma2012
- Author(s)
  Fertig EJ, Ren Q, Cheng H, Hatakeyama H, Dicker AP, Rodeck U, Considine M, Ochs MF, Chung CH
- Journal Title
  
  BMC Genomics
  
  Volume : 13 Pages : 160-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Platinum concentration in sentinel lymph nodes after preoperative intra-arterial cisplatin chemotherapy targeting primary tongue cancer2012
- Author(s)
  Sakashita T, Homma A, Oridate N, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Yoshida D, Fujima N, Fukuda S
- Journal Title
  
  Acta Otolaryngol
  
  Volume : 132 Issue : 10 Pages : 1121-1125
- Publisher
  Informa
- DOI
  10.3109/00016489.2012.680494
- PMID
  info:pmid/22667997
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-22791561, KAKENHI-PROJECT-23592517, KAKENHI-PROJECT-23791867, KAKENHI-PROJECT-24592587
[Journal Article] 【Best articles of the year】舌根癌における放射線同時併用超選択的動注化学療法.2012
- Author(s)
  加納里志, 本間明宏, 折舘伸彦, 鈴木章之, 畠山博充他.
- Journal Title
  
  北海道医誌
  
  Volume : 87 Pages : 208-208
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] ＜第13回耳鼻咽喉科手術支援システム･ナビ研究会＞早期舌癌におけるセンチネルリンパ節の領域分布に関する検討.2012
- Author(s)
  坂下智博, 本間明宏, 折舘伸彦, 鈴木清護, 畠山博充他
- Journal Title
  
  耳展
  
  Volume : 55 Pages : 364-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] Evaluation of nodal response after intra-arterial chemoradiation for node-positive head and neck cancer2012
- Author(s)
  Sakashita T, Homma A, Oridate N, Hatakeyama H, Kano S, Mizumachi T, Fukuda S
- Journal Title
  
  Eur Arch Otorhinolaryngol
  
  Volume : 269 Issue : 6 Pages : 1671-1676
- Publisher
  Springer Berlin / Heidelberg
- DOI
  10.1007/s00405-011-1814-5
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-22791561, KAKENHI-PROJECT-23592517, KAKENHI-PROJECT-23791867, KAKENHI-PROJECT-24592587
[Journal Article] 【Best articles of the year】口腔癌における超選択的シスプラチン動注化学療法後のセンチネルリンパ節内プラチナ濃度測定.2012
- Author(s)
  坂下智博, 本間明宏, 折舘伸彦, 鈴木清護, 畠山博充他.
- Journal Title
  
  北海道医誌
  
  Volume : 87 Pages : 261-261
- Data Source
  KAKENHI-PROJECT-24592587
[Journal Article] 頭頸部癌研究に関する最近の流れ－分子標的治療とHPV感染について-.2012
- Author(s)
  福田諭, 畠山博充.
- Journal Title
  
  耳鼻臨床
  
  Volume : 105 Pages : 183-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma.2012
- Author(s)
  Fertig EJ, Ren Q, Cheng H, Hatakeyama H,　et al.
- Journal Title
  
  BMC Genomics
  
  Volume : 13 Pages : 160-160
- DOI
  10.1186/1471-2164-13-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] 頭頸部癌研究に関する最近の流れ2012
- Author(s)
  福田　諭、畠山　博充
- Journal Title
  
  耳鼻臨床
  
  Volume : 105 Pages : 183-191
- DOI
  10.5631/jibirin.105.183
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] 【Best articles of the year】舌根癌における放射線同時併用超選択的動注化学療法.2012
- Author(s)
  加納里志, 本間明宏, 折舘伸彦, 鈴木章之, 畠山博充他
- Journal Title
  
  北海道医誌
  
  Volume : 87 Pages : 208-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] 【Best articles of the year】口腔癌における超選択的シスプラチン動注化学療法後のセンチネルリンパ節内プラチナ濃度測定.2012
- Author(s)
  坂下智博, 本間明宏, 折舘伸彦, 鈴木清護, 畠山博充他
- Journal Title
  
  北海道医誌
  
  Volume : 87 Pages : 261-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] 喉頭癌T3症例の治療成績の検討.2012
- Author(s)
  水町貴諭, 折舘伸彦, 本間明宏, 坂下智博, 加納里志, 畠山博充他
- Journal Title
  
  頭頸部外科
  
  Volume : 22 Pages : 317-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] ＜第13回耳鼻咽喉科手術支援システム･ナビ研究会＞早期舌癌におけるセンチネルリンパ節の領域分布に関する検討.2012
- Author(s)
  坂下智博, 本間明宏, 折舘伸彦, 鈴木清護, 畠山博充他
- Journal Title
  
  耳展
  
  Volume : 55 Pages : 364-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592517
[Journal Article] Combined modality therapy for laryngeal cancer with superselective intra-arterial cisplatin infusion and concomitant radiotherapy.2012
- Author(s)
  ④ Taki S, Homma A, Suzuki F, Oridate N, Hatakeyama H, Mizumachi T, Kano S, et al.
- Journal Title
  
  Int J Clin Oncol
  
  Volume : 17 Pages : 441-446
- DOI
  10.1007/s10147-011-0308-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791561, KAKENHI-PROJECT-23592517, KAKENHI-PROJECT-23791867, KAKENHI-PROJECT-24592587
[Journal Article] Regulation of heparin-binding EGF-like growth factor by miR-212 and acquired cetuximab-resistance in head and neck squamous cell carcinoma.2010
- Author(s)
  Hatakeyama H
- Journal Title
  
  PLoS One
  
  Volume : 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592008
[Journal Article] Regulation of heparin-binding EGF-like growth factor by miR-212 and acquired cetuximab-resistance in head and neck squamous cell carcinoma.2010
- Author(s)
  Hatakeyama H, et al
- Journal Title
  
  PLoS One 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592008
[Journal Article] Nuclear factor-kappa B pathway and response in a phase II trial of bortezomib and docetaxel in patients with recurrent and/or metastatic head and neck squamous cell carcinoma.2010
- Author(s)
  Chung CH, Aulino J, Muldowney NJ, Hatakeyama H, et al
- Journal Title
  
  Ann Oncol 21
  
  Pages : 864-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592008
[Presentation] 頭頸部癌における免疫チェックポイント分子と増殖・刺激因子シグナル伝達経路2016
- Author(s)
  畠山　博充
- Organizer
  第40回日本頭頸部癌学会
- Place of Presentation
  ソニックシティ（埼玉県さいたま市）
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-26462591
[Presentation] 頭頸部癌ゲノム・プロテオーム解析からの個別化分子標的治療へ2015
- Author(s)
  畠山博充　本間明宏　坂下智博　水町貴諭　加納里志　蠣崎文彦　福田諭
- Organizer
  第53回日本癌治療学会学術集会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2015-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26462591
[Presentation] Clinical adaptation of CRM197 for the treatment of head and neck cancer2015
- Author(s)
  Hiromitsu Hatakeyama 　Tomohiro Sakashita　Satoshi Kano 　Takatsugu Mizumachi　　Akihiro Homma　Satoshi Fukuda
- Organizer
  第53回日本癌治療学会学術集会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2015-10-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462591
[Presentation] The role of microRNAs in the malignant transformation of sinonasal inverted papilloma2015
- Author(s)
  Hiromitsu Hatakeyama, Yuji Nakamaru , Dai Takagi, Akihiro Homma,Takatsugu Mizumati Satoshi Kano, Tomohiro Sakashita and Satoshi Fukuda
- Organizer
  3rd Congress of European ORL-HNS
- Place of Presentation
  GUARANT International(Checz,Prague)
- Year and Date
  2015-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462591
[Presentation] The Role of MicroRNAs in the Malignant Transformation of Sinonasal Inverted Papilloma2013
- Author(s)
  Hiromitsu Hatakeyama
- Organizer
  ASHNO
- Place of Presentation
  Radisson Blu Hotel(Cebu city, Philippines)
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] Cervical lymph node metastasis of head and neck squamous carcinoma after chemoradiotherapy.2013
- Author(s)
  Akihiro HOMMA, Tomohiro SAKASHITA, Hiromitsu HATAKEYAMA, Satoshi KANO, Takatsugu MIZUMACHI, Nobuhiko ORIDATE, Satoshi FUKUDA
- Organizer
  20th IFOS World Congress
- Place of Presentation
  COEX Convention Center(Seoul, Korea)
- Data Source
  KAKENHI-PROJECT-24592587
[Presentation] Epithelial-Mesenchymal Transition in Human Papilloma Virus-Positive and -Negative Oropharyngeal Squamous Cell Carcinomas2013
- Author(s)
  Hiromitsu Hatakeyama
- Organizer
  AAO-HNSF 2013
- Place of Presentation
  Vancouver Convention Centre(Vancouver,Canada)
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] Epithelial-Mesenchymal Transition in Human Papilloma Virus Positive and Negative Oropharyngeal Squamous Cell Carcinoma2013
- Author(s)
  Hiromitsu Hatakeyama
- Organizer
  AAO-HNSF
- Place of Presentation
  Vancouver Convention and Exhibition Center,Vancouver,Canada
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] 分子標的薬の適正使用における感受性マーカーの開発2012
- Author(s)
  畠山博充
- Organizer
  第36回日本頭頸部癌学会
- Place of Presentation
  島根県民会館(松江市)
- Invited
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] 頭頸部および食道扁平上皮癌の網羅的ゲノム・プロテオーム解析2012
- Author(s)
  畠山博充
- Organizer
  第64回日本気管食道科学会
- Place of Presentation
  ホテル日航東京(東京)
- Invited
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] Nuclear factor-kB activation and cetuximab-resistance in HNSCC cell lines.2011
- Author(s)
  Hiromitsu Hatakeyama
- Organizer
  Asian Society of Head and Neck Oncology 2011
- Place of Presentation
  Grand Hyatt（India）
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] 頭頸部癌セツキシマブ耐性獲得におけるEGFRリガンドの発現とmicro RNA制御.2011
- Author(s)
  畠山　博充
- Organizer
  第112回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  国立京都国際会館（京都府)
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] 頭頸部癌におけるNF-kBパスウエイの活性化とセツキシマブ耐性.2011
- Author(s)
  畠山　博充
- Organizer
  第35回日本頭頸部癌学会
- Place of Presentation
  ウインクあいち（愛知県産業労働センター）（愛知県）
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] Regulation of HB-EGF by miR-212 and Acquired Cetuximab-Resistance in Head and Neck Squamous Cell Carcinomas.2011
- Author(s)
  畠山　博充
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] Insulin-like Growth Factor-I Receptor Inhibitor Sensitizes Head and Neck Cancer Cells to Cetuximab and Methotrexate.2009
- Author(s)
  Hatakeyama H
- Organizer
  45th Annual meeting of American Society of Clinical Oncology
- Place of Presentation
  オレンジカウンティコンベンシンセンター(Orlando, Florida)
- Data Source
  KAKENHI-PROJECT-20592008
[Presentation] Cetuximab sensitivity in head and neck squamous cell carcinoma cell lines based on the HPV status.2009
- Author(s)
  Hatakeyama H
- Organizer
  100^<th> Annual meeting of American Association for Cancer Research
- Place of Presentation
  デンバーコンベンションセンター(Denver, Colorado)
- Data Source
  KAKENHI-PROJECT-20592008
[Presentation] The efficacy of superselective intra-arterial infusion of cisplatin and concomitant radiotherapy for patients with locally advanced maxillary sinus cancer: a single institution experience.
- Author(s)
  28.Homma A, Sakashita T, Hatakeyama H, Furusawa J, Mizumachi T, Kano S, Inamura N, Taki S, Suzuki F, Yoshida D, Onimaru R, Tsuchiya K, Yasuda K, Nishikawa N, Shirato H, Fukuda F
- Organizer
  15th Korea-Japan Joint Meeting of Otorhinolaryngology - Head and Neck Surgery,
- Place of Presentation
  Lotte Hotel　Seoul　(Seoul, Korea）
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-24592587
[Presentation] ＜Symposium＞head and neck cancer「Superselective intra-arterial chemotherapy with concurrent radiotherapy for sinonasal malignant tumors.
- Author(s)
  Homma A, Oridate N, Sakashita T, Yoshida D, Onimaru R, Tsuchiya K, Hatakeyama H, Mizumachi T, Kano S, Shirato H, Fukuda S
- Organizer
  The 14th Japan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
- Place of Presentation
  京都ホテルオークラ（京都市）
- Data Source
  KAKENHI-PROJECT-24592587
[Presentation] The efficacy of superselective intra-arterial infusion with concomitant radiotherapy for adenoid cystic carcinoma of the head and neck.
- Author(s)
  Homma A, Oridate N, Sakashita T, Suzuki S, Hatakeyama H,et al.
- Organizer
  8th International Conference on Head & Neck Cancer
- Place of Presentation
  Metro Toronto Convention Center（カナダ）
- Data Source
  KAKENHI-PROJECT-24592587
[Presentation] Early and long-term morbidity after total laryngo-pharyngo-esophagectomy with gastic pull-up reconstruction
- Author(s)
  Homma A, Hatakeyama H, Mizumachi T, Kano S, Furusawa J, Sakashita T, Shichinohe T, Ebihara Y, Hirano S, Furukawa H, Yamamoto Y, Fukuda S.
- Organizer
  IFHNOS 5th World Congress and AHNS 2014 Annual Meeting
- Place of Presentation
  The Marriott Marquis Time Square（NY,USA)
- Year and Date
  2014-07-26 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-24592587
[Presentation] Lymph node metastasis in burns space
- Author(s)
  29.Homma A, Hatakeyama H, Mizumachi T, Furusawa J, Kano S, Sakashita T, Fukuda F
- Organizer
  18th World congress joint meeting of the world association for bronchology and interventional pulmonology & the international bronchoesophagology society
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-24592587
[Presentation] 中咽頭癌超選択的動注化学療法と放射線の同時併用療法後舌骨壊死への対応
- Author(s)
  畠山博充、本間明宏、坂下智博、加納里志、水町貴諭、福田諭
- Organizer
  第25回日本頭頸部外科学会総会ならびに学術講演会
- Place of Presentation
  コングレコンベンションセンター（大阪市）
- Year and Date
  2015-01-29 – 2015-01-30
- Data Source
  KAKENHI-PROJECT-26462591
[Presentation] セツキシマブ投与における EGFRリガンド発現変化と効果
- Author(s)
  畠山博充、本間明宏、坂下智博、加納里志、水町貴諭、福田諭
- Organizer
  第38回日本頭頸部癌学会
- Place of Presentation
  東京ファッションタウンビル（東京都）
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26462591
[Presentation] Antley-Bixler症候群における気道確保
- Author(s)
  畠山博充、本間明宏、坂下智博、加納里志、水町貴諭、福田諭
- Organizer
  第18回世界気管食道会議
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-26462591
[Presentation] ＜パネルディスカッション5＞頭頸部および食道扁平上皮癌の網羅的ゲノム、プロテオーム解析
- Author(s)
  畠山博充
- Organizer
  第64回日本気管食道科学会
- Place of Presentation
  ホテル日航東京（東京都港区）
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] ＜シンポジウム5＞分子標的薬の適正な使用について「分子標的薬の適性使用における感受性マーカーの開発.
- Author(s)
  畠山博充
- Organizer
  第36回日本頭頸部癌学会
- Place of Presentation
  島根県民会館（松江市）
- Invited
- Data Source
  KAKENHI-PROJECT-23592517
[Presentation] The role of microRNAs in the malignant transformation of sinonasal inverted papilloma.
- Author(s)
  Hatakeyama H, Kano S, Mizumachi T, Homma A, Fukuda S.
- Organizer
  8th International Conference on Head & Neck Cancer
- Place of Presentation
  Metro Toronto Convention Centre（Toronto,Canada）
- Invited
- Data Source
  KAKENHI-PROJECT-23592517

1. HOMMA Akihiro (30312359)

# of Collaborated Projects : 4results

# of Collaborated Products : 52results
2. Mizumachi Takatsugu

# of Collaborated Projects : 0results

# of Collaborated Products : 13results
3. Sakashita Tomohiro

# of Collaborated Projects : 0results

# of Collaborated Products : 4results
4. KANO Satoshi

# of Collaborated Projects : 0results

# of Collaborated Products : 4results
5. MATSUURA Kazuto

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
6. 杉山健一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
7. 佐邊壽孝

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 畑中豊

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
9. 橋本あり

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. 畠山鎮次

# of Collaborated Projects : 0results

# of Collaborated Products : 4results
11. 福田諭

# of Collaborated Projects : 0results

# of Collaborated Products : 3results
12. 加藤健吾

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 中丸裕爾

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

HATAKEYAMA Hiromitsu 畠山 博充

Research Projects

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頭頸部癌heterogeneityを引き起こす微小環境のオーム解析Principal InvestigatorOngoing

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Elucidation of signaling network of head and neck cancer by bioinformatics approachPrincipal Investigator

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Gene mutation and 3D-conformation of proteins related to EGFR pathway in head and neck cancer

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Network of signaling pathway of head and neck cancerPrincipal Investigator

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Identification of markers for overexpression of EGFR in head and neck cancer using genomics and proteomics

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[Journal Article] Expression of p53, p16, cyclin D1, epidermal growth factor receptor and Notch1 in patients with temporal bone squamous cell carcinoma.2017

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[Journal Article] The outcomes of surgery and chemoradiotherapy for temporal bone cancer.2016

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[Journal Article] Effectiveness of superselective intra-arterial chemoradiotherapy targeting retropharyngeal lymph node metastasis.2016

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[Journal Article] The role of prophylactic neck dissection and tumor thickness evaluation for patients with cN0 tongue squamous cell carcinoma.2016

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[Journal Article] A retrospective study of G-tube use in Japanese patients treated with concurrent chemoradiotherapy for hypopharyngeal cancer.2016

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[Journal Article] Decreased SMAD4 expression is associated with induction of epithelial-to-mesenchymal transition and cetuximab resistance in head and neck squamous cell carcinoma.2015

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[Journal Article] Hangeshashinto improves the completion rate of chemoradiotherapy and the nutritional status in patients with head and neck cancer.2015

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[Journal Article] Hangeshashinto Improves the Completion Rate of Chemoradiotherapy and the Nutritional Status in Patients with Head and Neck Cancer2015

HATAKEYAMA Hiromitsu 畠山博充

[Journal Article] 中央咽頭扁平上皮癌症例に対するWeekly CDDP併用　化学放射線療法の臨床的検討2014