NOGUCHI Akira 野口映

Researcher Number	10456395
Other IDs
Affiliation (based on the past Project Information) *help	2018: 富山大学, 大学院医学薬学研究部(医学), 助教 2015 – 2017: 聖マリアンナ医科大学, 医学部, 助教 2011 – 2015: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, その他 2014: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), がん生物学部, 特別研究員 2014: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), がん生物学部, 研究員 2013: 地方独立行政法人神奈川県立病院機構, 神奈川県立がんセンター病院, 任期付医員 2013: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 病理診断科, 任期付医師
Review Section/Research Field	Principal Investigator Surgical dentistry Except Principal Investigator Surgical dentistry
Keywords	Principal Investigator 頭頸部癌 / 扁平上皮癌 / 口腔癌 / 頭頚部癌 / 頭頸部扁平上皮癌 / EGFR / セツキシマブ / エピジェネティクス / SIRT1 / HDAC / ヒストン脱アセチル化酵素 … More Except Principal Investigator … More SIRT1 / 頭頸部癌 / 口腔扁平上皮癌 / 頭頸部がん / 頭頚部癌 / TAp63 / SIRT1発現 / エピジェネティクス / 頭頸部扁平上皮癌 / 癌抑制遺伝子 / 脱アセチル化酵素 Less

The search of factor which regulate sensitivity to cetuximab focused on immunological alterationPrincipal Investigator
- Principal Investigator
  
  Noguchi Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Toyama
  St. Marianna University School of Medicine
Intracellular localization of SIRT1 in oral squamous cell carcinoma
- Principal Investigator
  
  Ohtsu Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanagawa Cancer Center Research Institute
A cellular biological study on assessment of the deacetylase SIRT1 expression in oral squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  Noguchi Akira
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanagawa Cancer Center Research Institute
Subcellular localization and biological functions of SIRT1 in head and neck squamous cell carcinoma
- Principal Investigator
  
  KIKUCHI Keiji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanagawa Cancer Center Research Institute
Establishment of predictive equation for the prognosis of oral squamous cell carcinoma patients on the basis of the expression of ING gene family
- Principal Investigator
  
  TAKANO Yasuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanagawa Cancer Center Research Institute

All 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Association of SIRT1 and the tumor-suppressor gene TAp63 expression in head and neck squamous cell carcinoma2015
- Author(s)
  Kikuchi K, Noguchi A, Kasajima R, Miyagi Y, Hoshino D, Koshikawa N, Kubota A, Yokose T, Takano Y.
- Journal Title
  
  Tumor Biology
  
  Volume: in press Issue: 10 Pages: 7865-72
- DOI
  10.1007/s13277-015-3515-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24593043, KAKENHI-PROJECT-25861990
[Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer.2014
- Author(s)
  Noguchi A, Kikuchi K, Zheng H, Takahashi H, Miyagi Y, Aoki I, Takano Y.
- Journal Title
  
  Cancer Med.
  
  Volume: 3 Issue: 6 Pages: 1553-61
- DOI
  10.1002/cam4.310
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24593043, KAKENHI-PROJECT-25861990, KAKENHI-PROJECT-221S0001
[Journal Article] Gene profile analyses of lens tumor, liver and spleen in α-crystallin/SV40 T antigen transgenic mice treated with Juzentaihoto, a Chinese medicine.2014
- Author(s)
  Zheng H, Nakamura T, Noguchi A, Kikuchi K, Ando T, Takano Y.
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 9 Issue: 2 Pages: 547-552
- DOI
  10.3892/mmr.2013.1854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659958, KAKENHI-PROJECT-24593043
[Journal Article] High SIRT1 expression and low DBC1 expression are associated with poor prognosis in colorectal cancer.2013
- Author(s)
  Kikuchi K, Noguchi A, Takahashi H, Zheng H, Kameda Y, Sekiguchi H, Akaike M, Miyagi Y, Takano Y.
- Journal Title
  
  J. Cancer Therapeutics Res.
  
  Volume: 2 Issue: 1 Pages: 1-8
- DOI
  10.7243/2050-120x-2-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593043
[Journal Article] SIRT1 expression is associated with good prognosis for head and neck squamous cell carcinoma patients.2013
- Author(s)
  Noguchi A, Li X, Kubota A, Kikuchi K, Kameda Y, Zheng H, Miyagi Y, Aoki I, Takano Y.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol
  
  Volume: 115 Issue: 3 Pages: 385-92
- DOI
  10.1016/j.oooo.2012.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659958, KAKENHI-PROJECT-24593043, KAKENHI-PROJECT-25861990
[Journal Article] Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model.2013
- Author(s)
  Noguchi A, Kikuchi K, Ohtsu T, Yoshiwara M, Nakamura Y, Miyagi Y, Zheng H, Takano Y.
- Journal Title
  
  Oncology Reports
  
  Volume: 30 Issue: 6 Pages: 2603-2608
- DOI
  10.3892/or.2013.2782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659958, KAKENHI-PROJECT-24593043
[Presentation] JCV T 抗原TG マウスに発生した肺腫瘍の病理学的検討2013
- Author(s)
  野口映、髙野康雄
- Organizer
  日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] SIRT1 high-expression and low expression of SIRT1 inhibitor DBC1 correlates poor prognosis of colon cancer patients2012
- Author(s)
  Kikuchi K, Noguchi A, Takano Y
- Organizer
  癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] High expression is associated with poorer survival in patients with gastric cancer2012
- Author(s)
  Noguchi A, Kikuchi K, Takano Y
- Organizer
  癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] SIRT1 核発現は頭頸部扁平上皮癌の進展・予後のバイオマーカーである2012
- Author(s)
  野口映、菊地慶司、高野康雄
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] Subnuclar localization and degradation of ING4 is correlated with tumotigenesis and progression of HNSCC2011
- Author(s)
  Noguchi A, Takano Y, Kikuchi K
- Organizer
  癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] SIRT1 overexpression is an independent poor prognostic indicator of colorectal cancer patients2011
- Author(s)
  Kikuchi K, Noguchi A, Takano Y
- Organizer
  癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] human papillomavirus発現が頭頚部扁平上皮癌治療に与える影響
- Author(s)
  佐藤要、高野康男、久保田彰、野口映、木谷洋輔
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] SIRT1の高発現は胃癌における予後不良因子である.
- Author(s)
  3) 野口映, 菊地慶司, 高野康雄
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] SIRT1核発現は頭頸部扁平上皮癌の進展・予後のバイオマーカーである
- Author(s)
  野口　映
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659958
[Presentation] SIRT1 high-expression and low expression f SIRT1 inhibitor DBC1 correlates poor prognosis of colon cancer patients.
- Author(s)
  菊地慶司, 野口映, 高野康雄
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] NOGマウスによる高効率がん患者由来xenograft株の樹立
- Author(s)
  千々和剛、宮城洋平、川井健司、野口映、山田六平、末水洋志、高野康男、中村雅登
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] 頭頚部癌細胞におけるヒストン脱アセチル化酵素SIRT1の癌化形質への関与
- Author(s)
  菊地慶司, 野口映, 高野康雄
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24593043
[Presentation] SIRT1核発現は頭頸部扁平上皮癌の進展・予後のバイオマーカーである．
- Author(s)
  野口映, 高野康雄
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24593043

1. TAKANO Yasuo (60142022)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. NOGUCHI Makoto (50208328)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
3. KATAYAMA Kayoko (70584374)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KIKUCHI Keiji (90372094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. Ohtsu Takashi (10270696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 笠島理加 (20630875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NOGUCHI Akira 野口 映

Research Projects

Research Products

Co-Researchers

The search of factor which regulate sensitivity to cetuximab focused on immunological alterationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Intracellular localization of SIRT1 in oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A cellular biological study on assessment of the deacetylase SIRT1 expression in oral squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Subcellular localization and biological functions of SIRT1 in head and neck squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of predictive equation for the prognosis of oral squamous cell carcinoma patients on the basis of the expression of ING gene family

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association of SIRT1 and the tumor-suppressor gene TAp63 expression in head and neck squamous cell carcinoma2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene profile analyses of lens tumor, liver and spleen in α-crystallin/SV40 T antigen transgenic mice treated with Juzentaihoto, a Chinese medicine.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High SIRT1 expression and low DBC1 expression are associated with poor prognosis in colorectal cancer.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SIRT1 expression is associated with good prognosis for head and neck squamous cell carcinoma patients.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] JCV T 抗原TG マウスに発生した肺腫瘍の病理学的検討2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SIRT1 high-expression and low expression of SIRT1 inhibitor DBC1 correlates poor prognosis of colon cancer patients2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] High expression is associated with poorer survival in patients with gastric cancer2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SIRT1 核発現は頭頸部扁平上皮癌の進展・予後のバイオマーカーである2012

NOGUCHI Akira 野口映