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Koizumi Shinichiro  小泉 慎一郎

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KOIZUMI Shinichiro  小泉 慎一郎

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Researcher Number 10456577
Other IDs
Affiliation (Current) 2025: 浜松医科大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help 2021 – 2024: 浜松医科大学, 医学部附属病院, 講師
2016 – 2020: 浜松医科大学, 医学部附属病院, 助教
2010: Hamamatsu University School of Medicine, 医学部・脳神経外科学, リサーチアシスタント
2009 – 2010: Hamamatsu University School of Medicine, 医学部, リサーチアシスタント
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related / Neurosurgery / Cerebral neurosurgery
Except Principal Investigator
Basic Section 56010:Neurosurgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Neurosurgery
Keywords
Principal Investigator
悪性脳腫瘍 / 腫瘍溶解ウイルス療法 / グリオーマ幹細胞 / 腫瘍溶解ウイルス / ヒト脱落乳歯歯髄幹細胞 / 頭蓋内腫瘍弾性率 / 弾性率 / 頭蓋内腫瘍 / 走査型超音波顕微鏡 / 核磁気共鳴エラストグラフィー … More / チミジンキナーゼ / iPS細胞 / 遺伝子治療 / 脳腫瘍 / 脳腫瘍学 … More
Except Principal Investigator
SHED / 抗腫瘍効果 / 遺伝子細胞治療 / 自殺遺伝子療法 / HSVtk / 脂肪滴 / 悪性転化 / Stearoyl CoA desaturase / IDH変異神経膠腫 / 浸潤 / PDX / TK/GCV / PDXモデル / 自殺遺伝子治療 / 脳腫瘍 / 乳児歯髄幹細胞 / 腫瘍溶解ウイルス / 転移性脳腫瘍 / Muse-tk細胞 / 脱落乳歯歯髄幹細胞 / thymidine kinase / bystander effect / Stem cell / matastatic brain tumor / 肺癌脳転移 / HSV-TK / 歯髄幹細胞 / 遺伝子導入 / 製剤化 / TERT / hTERT遺伝子 / 遺伝子治療 / 細胞治療 / 幹細胞 / クローン化 / 細胞寿命 / TERT遺伝子 / HSVtk遺伝子 / 悪性グリオーマ / 組織幹細胞 / 脳腫瘍学 / HSVtk/GCV system / エピソーマルベクター / non-viral vector / PiggyBac system / HSVtk/GCV system / 自殺遺伝子幹細胞療法 Less
  • Research Projects

    (8 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (10 People)
  •  New phase of brain tumor therapy: development of gene and cell therapy with SHED

    • Principal Investigator
      黒住 和彦
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  細胞小器官脂質解析によるIDH変異神経膠腫の悪性化機序の解明と治療標的分子の探索

    • Principal Investigator
      山崎 友裕
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  悪性脳腫瘍に対するヒト脱落乳歯歯髄幹細胞を用いた新規腫瘍溶解ウイルス療法Principal Investigator

    • Principal Investigator
      小泉 慎一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  Construction of HSVtk transgenic cell lines for formulation of malignant glioma therapies

    • Principal Investigator
      Ikeno Masashi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Aichi Medical University
  •  Novel therapeutic strategy for brain metastasis of lung cancer using herpes simplex thymidine kinase bearing Muse cells.

    • Principal Investigator
      Sameshima Tetsuro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  Evaluation of the brain tumor elasticity by using Magnetic Resonance Elastography and Scanning Acoustic MicroscopyPrincipal Investigator

    • Principal Investigator
      Koizumi Shinichiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Hamamatsu University School of Medicine
  •  Development of suicide gene stem cell therapy by non-viral gene transfer method and application to glioma therapy

    • Principal Investigator
      sameshima tetsuro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Hamamatsu University School of Medicine
  •  Study of bystander effect in the therapy of malignant gliomas by using induced pluripotent stem cell transduced with herpes simplex virus-thymidine kinase gene and ganciclovirPrincipal Investigator

    • Principal Investigator
      KOIZUMI Shinichiro
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Hamamatsu University School of Medicine

All 2024 2023 2022 2020 2017 2011 2010

All Journal Article Presentation

  • [Journal Article] Midline invasion predicts poor prognosis in diffuse hemispheric glioma, H3 G34-mutant: an individual participant data review2024

    • Author(s)
      Kegoya Yasuhito、Otani Yoshihiro、Inoue Yohei、Mizuta Ryo、Higaki Fumiyo、Washio Kana、Koizumi Shinichiro、Kurozumi Kazuhiko、Ishida Joji、Fujii Kentaro、Yamamoto Norio、Tanaka Yoshihiro、Date Isao
    • Journal Title

      Journal of Neuro-Oncology

      Volume: 167 Issue: 1 Pages: 201-210

    • DOI

      10.1007/s11060-024-04587-5

    • Data Source
      KAKENHI-PROJECT-23K27710
  • [Journal Article] Mesenchymal stem cells as therapeutic vehicles for glioma2024

    • Author(s)
      Oishi Tomoya、Koizumi Shinichiro、Kurozumi Kazuhiko
    • Journal Title

      Cancer Gene Therapy

      Volume: - Issue: 9 Pages: 1306-1314

    • DOI

      10.1038/s41417-024-00775-7

    • Data Source
      KAKENHI-PROJECT-23K27710
  • [Journal Article] Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth2023

    • Author(s)
      Horikawa M, Koizumi S, Oishi T, Yamamoto T, Ikeno M, Ito M, Yamasaki T, Amano S, Sameshima T, Mitani Y, Otani Y, Yan Y, Suzuki T, Namba H, Kurozumi K
    • Journal Title

      Cancer Gene Therapy

      Volume: 30 Issue: 1 Pages: 85-95

    • DOI

      10.1038/s41417-022-00527-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07289, KAKENHI-PROJECT-19K07761, KAKENHI-PROJECT-20K09325, KAKENHI-PROJECT-21K20803, KAKENHI-PROJECT-17K10861
  • [Journal Article] Molecular Mechanisms and Clinical Challenges of Glioma Invasion2022

    • Author(s)
      Tomoya Oishi, Shinichiro Koizumi, Kazuhiko Kurozumi
    • Journal Title

      Brain Sciences

      Volume: 20;12(2) Issue: 2 Pages: 291-291

    • DOI

      10.3390/brainsci12020291

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09523, KAKENHI-PROJECT-20K09325
  • [Journal Article] Migration of mouse induced pluripotent stem cells to glioma conditioned medium is mediated by tumor-associated specific growth factors2011

    • Author(s)
      Shinichiro Koizumi
    • Journal Title

      Oncology Letter 2

      Pages: 283-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791354
  • [Journal Article] Migration of mouse induced pluripotent stem cells to glioma conditioned medium is mediated by tumor-associated specific growth factors2011

    • Author(s)
      Shinichiro Koizumi
    • Journal Title

      Oncology Letter

      Volume: 2 Pages: 283-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791354
  • [Presentation] グリオーマを標的としたStearoyl-CoA desaturase阻害剤のアポトーシス誘導に与える外因性脂肪酸の影響2023

    • Author(s)
      山﨑友裕, 神尾佳宣, Liu Zhitong, 小泉慎一郎, 黒住和彦
    • Organizer
      2023日本脳腫瘍学会
    • Data Source
      KAKENHI-PROJECT-23K08539
  • [Presentation] グリオーマにおける脂肪酸新生阻害剤と脂肪酸トランスポーター阻害剤の併用効果2023

    • Author(s)
      山﨑友裕 小泉慎一郎 黒住和彦
    • Organizer
      The 23rd Annual Meeting of the Japan Society of Molecular Neurosurgery
    • Data Source
      KAKENHI-PROJECT-23K08539
  • [Presentation] マルチモダリティーを用いた小児脳腫瘍手術2023

    • Author(s)
      14.黒住和彦、小泉慎一郎、根木宏明、橋本宗明、坂本量哉、山﨑友裕、大石知也、鮫島哲朗
    • Organizer
      第51回日本小児神経外科学会
    • Data Source
      KAKENHI-PROJECT-23K27710
  • [Presentation] グリオーマに対する脂肪酸トランスポーター阻害効果2023

    • Author(s)
      山崎 友裕, 神尾 佳宣, Liu Zhitong, 小泉 慎一郎, 黒住 和彦, Larion Mioara
    • Organizer
      2023日本脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-23K08539
  • [Presentation] 経鼻内視鏡頭蓋底手術における低侵襲多層再建法の現状2023

    • Author(s)
      黒住和彦、小泉慎一郎、石川竜司、大石知也、鮫島哲朗
    • Organizer
      第35回日本頭蓋底外科学会
    • Data Source
      KAKENHI-PROJECT-23K27710
  • [Presentation] 経鼻内視鏡手術における吸引イリゲーションによる腫瘍剥離の工夫2023

    • Author(s)
      黒住和彦、小泉慎一郎、石川竜司、大石知也、根木宏明、鮫島哲朗
    • Organizer
      第30回日本神経内視鏡学会
    • Data Source
      KAKENHI-PROJECT-23K27710
  • [Presentation] 外視鏡手術のフォアフロントーロボティクスとの併用―2023

    • Author(s)
      8.黒住和彦、小泉慎一郎、大石知也、山﨑友裕、神尾佳宣、根木宏明、鮫島哲朗
    • Organizer
      日本脳神経外科学会 第82回学術総会
    • Data Source
      KAKENHI-PROJECT-23K27710
  • [Presentation] 悪性gliomaに対するHSV由来TK遺伝子導入ヒト乳児歯髄幹細胞の治療応用の可能性2020

    • Author(s)
      堀川 真、小泉慎一郎、大石智也、山本泰資、伊藤昌彦、池野正史、難波宏樹、黒住和彦
    • Organizer
      第38回 日本脳腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07761
  • [Presentation] 核磁気共鳴エラストグラフィー と走査型超音波顕微鏡による脳腫瘍弾性率の評価2017

    • Author(s)
      小泉慎一郎
    • Organizer
      日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10889
  • [Presentation] 核磁気共鳴エラストグラフィー と走査型超音波顕微鏡による髄膜腫硬度の評価2017

    • Author(s)
      小泉慎一郎
    • Organizer
      日本脳腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-17K10889
  • [Presentation] 核磁気共鳴エラストグラフィー と走査型超音波顕微鏡による下垂体腺腫弾性率の評価2017

    • Author(s)
      小泉慎一郎
    • Organizer
      日本間脳下垂体腫瘍学会
    • Data Source
      KAKENHI-PROJECT-17K10889
  • [Presentation] マウスiPS細胞における悪性神経膠腫、specific growth factorsへの移動能の基礎評価2010

    • Author(s)
      小泉慎一郎
    • Organizer
      第11回日本分子脳神経外科学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-21791354
  • [Presentation] Migration of mouse induced pluripotent stem cells to glioma conditioned medium is mediated by tumor-associated specific growth factors2010

    • Author(s)
      Shinichiro Koizumi
    • Organizer
      10th Kyungpook Hamamatsu Joint Medical Symposium
    • Place of Presentation
      Hamamatsu
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21791354
  • [Presentation] Migration of mouse induced pluripotent stem cells to glioma conditioned medium is mediated by tumor-associated specific growth factors2010

    • Author(s)
      Shinichiro Koizumi
    • Organizer
      10th Kyungpook-Hamamatsu Joint Medical Symposium
    • Place of Presentation
      Hamamatsu
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21791354
  • [Presentation] マウスiPS細胞における、悪性神経膠腫および成長因子への移動能、特異的指向性の基礎評価2010

    • Author(s)
      小泉慎一郎
    • Organizer
      第69回日本脳神経外科学会総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21791354
  • [Presentation] マウスiPS細胞における悪性神経膠腫、成長因子への移動能の評価2010

    • Author(s)
      小泉慎一郎
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21791354
  • [Presentation] in vitro、in vivoにおける悪性神経膠腫へのマウスiPS細胞の移動能の基礎評価2010

    • Author(s)
      小泉慎一郎
    • Organizer
      第28回日本脳腫瘍学会
    • Place of Presentation
      軽井沢
    • Data Source
      KAKENHI-PROJECT-21791354
  • 1.  sameshima tetsuro (00295213)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  難波 宏樹 (60198405)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  山崎 友裕 (40781050)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  黒住 和彦 (20509608)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 5.  大石 知也 (50972428)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 6.  Ikeno Masashi (80298546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  三浦 克敏 (20173974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  武内 恒成 (90206946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  根木 宏明 (10750193)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 10.  山岸 覚 (40372362)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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