Ashino Shigeru 芦野滋

Researcher Number	10507221
Other IDs
Affiliation (Current)	2026: 京都大学, 成長戦略本部, 特定講師
Affiliation (based on the past Project Information) *help	2024: 京都大学, 成長戦略本部, 特定講師 2020 – 2023: 京都大学, オープンイノベーション機構, 特定講師 2019: 東京女子医科大学, 医学部, 講師 2015 – 2018: 東京女子医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 気管支喘息 / ウィルス感染 / ウイルス感染 / アレルギー・ぜんそく / 重症気管支喘息 / 自然リンパ球 / ヘルパーT細胞 / 気管支喘息増悪 / 免疫学 / ウィルス … More / 難治性気管支喘息 / Th17 / Th1 / アレルギー / 重症喘息 / 呼吸器疾患 Less

Research Projects
(5 results)
Research Products
(11 results)

RSV感染によって誘導されるTLR3経路依存的な重症喘息の病態解明と制御法開発Principal Investigator
- Principal Investigator
  
  芦野滋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kyoto University
Viral nucleic acid components-based mechanisms of RSV-induced asthma exacerbation and the strategy for controlling the pathogensisPrincipal Investigator
- Principal Investigator
  
  Ashino Shigeru
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kyoto University
Development of a therapeutic method for asthma exacerbation with cross-talk of immune- and peripheral nervous-systemPrincipal Investigator
- Principal Investigator
  
  ASHINO Shigeru
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
  Tokyo Women's Medical University
The mechanisms of asthma exacerbation induced by viral infection and the development of strategy for controlling the pathogenesis(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Ashino Shigeru
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokyo Women's Medical University
Elucidation of mechanisms for developing new strategies on a viral infection-induced steroid-resistant asthmaPrincipal Investigator
- Principal Investigator
  
  Ashino Shigeru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokyo Women's Medical University

All 2020 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children2020
- Author(s)
  Wang Meiqin、Strand Matthew J.、Lanser Bruce J.、Santos Carah、Bendelja Kreso、Fish Jennifer、Esterl Elizabeth A.、Ashino Shigeru、Abbott Jordan K.、Knight Vijaya、Gelfand Erwin W.
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 6 Pages: e0233563-e0233563
- DOI
  10.1371/journal.pone.0233563
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16064
[Journal Article] Effect of Cholecalciferol in Food Allergy Mouse Model Is Associated with Decrease of CD69<sup>+</sup> CD4<sup>+</sup> T Cells2019
- Author(s)
  Zaim E, Ashino S, Osaka T, Yanagisawa N, Yagi J
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 65 Issue: 2 Pages: 113-122
- DOI
  10.3177/jnsv.65.113
- NAID
  130007639843
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2019-04-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16064, KAKENHI-PROJECT-15KK0321
[Presentation] Double But Not Single-Stranded RNA Exacerbates Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation2020
- Author(s)
  Shigeru Ashino, Katsuyuki Takeda, Hidemitsu Kitamura, Atsushi Kurokawa, Tomohiro Akaba, Mitsuko Kondo, Kiyoshi Takeyama, Etsuko Tagaya, Naoko Yanagisawa, and Erwin W. Gelfand
- Organizer
  American Academy of Allergy Asthma and Immunology International Annual Meeting 2020 (新型コロナウイルス感染拡大のためabstractのみ発表)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16064
[Presentation] Double But Not Single-Stranded RNA Exacerbates Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation2020
- Author(s)
  Shigeru Ashino, Katsuyuki Takeda, Hidemitsu Kitamura, Atsushi Kurokawa, Tomohiro Akaba, Mitsuko Kondo, Kiyoshi Takeyama, Etsuko Tagaya, Naoko Yanagisawa, and Erwin W. Gelfand
- Organizer
  American Academy of Allergy Asthma and Immunology (新型コロナウイルス感染拡大のためabstractのみ公表)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0321
[Presentation] Double But Not Single-Stranded RNA derived from Respiratory Syncytial Virus Exacerbates Allergen-Induced Airway Inflammation2020
- Author(s)
  Shigeru Ashino, Katsuyuki Takeda, Azzeddine Dakhama, Atsushi Kurokawa, Kondo Mitsuko, Kiyoshi Takeyama, Etsuko Tagaya, Naoko Yanagisawa, and Erwin W. Gelfand
- Organizer
  American Thoracic Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16064
[Presentation] The Effects of Viral Components, Single-Stranded RNA and Double-Stranded RNA, on Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation.2018
- Author(s)
  Shigeru Ashino, Hidemitsu Kitamura, Tomohiro Akaba, Kiyoshi Takeyama, Jun Tamaoki, and Junji Yagi.
- Organizer
  American Thoracic Society International Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16064
[Presentation] The Crucial Roles of Neurokinin A and Neurokinin Receptor 2 Signaling in Asthma Exacerbation Induced by a Viral Component, Double-Stranded RNA.2018
- Author(s)
  Shigeru Ashino, Hidemitsu Kitamura, Tomohiro Akaba, Kiyoshi Takeyama, Jun Tamaoki, and Junji Yagi.
- Organizer
  第67回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16064
[Presentation] The Effects of Viral Components, Single-Stranded RNA and Double-Stranded RNA, on Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation.2018
- Author(s)
  Shigeru Ashino, Hidemitsu Kitamura, Tomohiro Akaba, Kiyoshi Takeyama, Jun Tamaoki, and Junji Yagi.
- Organizer
  American Thoracic Society International Conference 2018.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0321
[Presentation] The Crucial Roles of Neurokinin A and Neurokinin Receptor 2 Signaling in Asthma Exacerbation Induced by a Viral Component, Double-Stranded RNA.2018
- Author(s)
  Shigeru Ashino, Hidemitsu Kitamura, Tomohiro Akaba, Kiyoshi Takeyama, Jun Tamaoki, and Junji Yagi.
- Organizer
  第67回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-15KK0321
[Presentation] Crucial timing of a viral component exposure to exacerbate allergen-induced asthma2016
- Author(s)
  Shigeru Ashino
- Organizer
  European Respiratory Society International Conference 2016
- Place of Presentation
  London, UK
- Year and Date
  2016-09-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19431
[Presentation] The Effects of Double-Stranded RNA on Allergen-Induced Eosinophilic Airway Inflammation in a Mouse Model2015
- Author(s)
  Shigeru Ashino, Kiyoshi Takeyama, Tomohiro Akaba, Jun Tamaoki, and Junji Yagi
- Organizer
  American Thoracic Society International Conference 2015
- Place of Presentation
  Denver, CO, U.S.A.
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19431

Ashino Shigeru 芦野 滋

Research Projects

Research Products

RSV感染によって誘導されるTLR3経路依存的な重症喘息の病態解明と制御法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Viral nucleic acid components-based mechanisms of RSV-induced asthma exacerbation and the strategy for controlling the pathogensisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a therapeutic method for asthma exacerbation with cross-talk of immune- and peripheral nervous-systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanisms of asthma exacerbation induced by viral infection and the development of strategy for controlling the pathogenesis(Fostering Joint International Research)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of mechanisms for developing new strategies on a viral infection-induced steroid-resistant asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Cholecalciferol in Food Allergy Mouse Model Is Associated with Decrease of CD69<sup>+</sup> CD4<sup>+</sup> T Cells2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Presentation] Double But Not Single-Stranded RNA Exacerbates Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation2020

Author(s)

Organizer

Data Source

[Presentation] Double But Not Single-Stranded RNA Exacerbates Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation2020

Author(s)

Organizer

Data Source

[Presentation] Double But Not Single-Stranded RNA derived from Respiratory Syncytial Virus Exacerbates Allergen-Induced Airway Inflammation2020

Author(s)

Organizer

Data Source

[Presentation] The Effects of Viral Components, Single-Stranded RNA and Double-Stranded RNA, on Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation.2018

Author(s)

Organizer

Data Source

[Presentation] The Crucial Roles of Neurokinin A and Neurokinin Receptor 2 Signaling in Asthma Exacerbation Induced by a Viral Component, Double-Stranded RNA.2018

Author(s)

Organizer

Data Source

[Presentation] The Effects of Viral Components, Single-Stranded RNA and Double-Stranded RNA, on Allergen-Induced Airway Hyperresponsiveness and Airway Inflammation.2018

Author(s)

Organizer

Data Source

[Presentation] The Crucial Roles of Neurokinin A and Neurokinin Receptor 2 Signaling in Asthma Exacerbation Induced by a Viral Component, Double-Stranded RNA.2018

Author(s)

Organizer

Data Source

[Presentation] Crucial timing of a viral component exposure to exacerbate allergen-induced asthma2016

Author(s)

Organizer

Place of Presentation

Year and Date

Ashino Shigeru 芦野滋