OKUI Takafumi 奥井隆文

Researcher Number	10509540
Affiliation (based on the past Project Information) *help	2012 – 2014: 新潟大学, 医歯学総合病院, 医員 2008 – 2011: 新潟大学, 医歯学系, 特任助教
Review Section/Research Field	Principal Investigator Periodontal dentistry / Periodontology Except Principal Investigator Periodontal dentistry
Keywords	Principal Investigator 歯周炎 / サブセット転換 / Treg / Th17 / 骨保護作用 / マウスモデル / 咬合性外傷 / 抗炎症性作用 / 歯肉上皮細胞 / レスベラトロール … More / IL-17+FOXP3+T細胞 / IL-17+FOXP3+細胞 / RANKL / 制御性T細胞 / 免疫組織学的解析 / フローサイトメトリー / CD4^+T細胞ライン / FOXP3 / IL-17 / 歯周免疫機能学 … More Except Principal Investigator TH17 / Th17 / RANKL / 歯周炎 Less

歯周炎予防・治療におけるレスベラトロールの応用に向けた基礎的な研究Principal Investigator
- Principal Investigator
  
  奥井隆文
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Niigata University
The effect of Treg-Th17 conversion induced by periodontopathicbacteria on osteoclastogenesis.Principal Investigator
- Principal Investigator
  
  OKUI Takafumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Niigata University
Analysis of periodontitis lesions focusing on a new T-cell subset, Th17.Principal Investigator
- Principal Investigator
  
  OKUI Takafumi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Niigata University
The role of effector T cells on bone resorption in periodontal diseased lesons
- Principal Investigator
  
  ITO Harue
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Niigata University

All 2015 2014 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Resveratrol suppresses the inflammatory responses of human gingival epithelial cells in a SIRT1 independent manner2015
- Author(s)
  Minagawa T, Okui T, Takahashi N, Nakajima T, Tabeta K, Murakami S, Yamazaki K
- Journal Title
  
  J Periodontal Res
  
  Volume: 未定 Issue: 5 Pages: 586-593
- DOI
  10.1111/jre.12238
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25463215, KAKENHI-PROJECT-25463216
[Journal Article] The role of distinct T cell subsets in periodontitis - Studies from humans and rodent models.2014
- Author(s)
  Okui T, Aoki-Nonaka Y, Nakajima T, Yamazaki K.
- Journal Title
  
  Cur Oral Health Rep.
  
  Volume: 1 Issue: 2 Pages: 114-123
- DOI
  10.1007/s40496-014-0013-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390476, KAKENHI-PROJECT-25463215, KAKENHI-PROJECT-25893079
[Journal Article] Increased serum PCSK9 concentrations are associated with periodontal infection but do not correlate with LDL cholesterol concentration2012
- Author(s)
  宮沢、土門, ら
- Journal Title
  
  Clin Chim Acta
  
  Volume: 413 Issue: 1-2 Pages: 154-159
- DOI
  10.1016/j.cca.2011.09.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J01295, KAKENHI-PROJECT-23390476, KAKENHI-PROJECT-23659974, KAKENHI-PROJECT-23792469, KAKENHI-PROJECT-23792470
[Journal Article] The effects of systemic sitafloxacin on periodontal infection control in elderly patients2012
- Author(s)
  Nakajima T, Ito H, Yamazaki K, 他5名
- Journal Title
  
  Gerodontology
  
  Volume: (in press) Issue: 2 Pages: 1024-32
- DOI
  10.1111/j.1741-2358.2011.00605.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390555, KAKENHI-PROJECT-23659974, KAKENHI-PROJECT-23792469
[Journal Article] The presence of IL-17^+/FOXP3^+ double-positive cells in periodontitis2012
- Author(s)
  Okui T, Aoki Y, Ito H, Honda T, Yamazaki K
- Journal Title
  
  J Dent Res
  
  Volume: 91(6) Issue: 6 Pages: 574-579
- DOI
  10.1177/0022034512446341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390476, KAKENHI-PROJECT-23792469, KAKENHI-PROJECT-23792470
[Journal Article] Elevated antibody titers to Porphyromonas gingivalis as a possible predictor of ischemic vascular disease - results from the Tokamachi-Nakasato cohort study2011
- Author(s)
  Tabeta K, Tanabe N, Yonezawa D, Miyashita H, Maekawa T, Takahashi N, Okui T, Nakajima T, Yamazaki K
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 18 Pages: 808-17
- NAID
  130004845393
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21670558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792469
[Journal Article] Effect of interleukin-17 on the expression of chemokines in gingival epithelial cells2011
- Author(s)
  Takahashi N, Okui T, Tabeta K, Yamazaki K
- Journal Title
  
  Eur J Oral Sci
  
  Volume: 119 Issue: 5 Pages: 339-44
- DOI
  10.1111/j.1600-0722.2011.00842.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792469, KAKENHI-PROJECT-23792470
[Journal Article] Porphyromonas gingivalis antigens and interleukin-6 stimulate the production of monocyte chemoattractant protein-1 via the upregulation of early growth response-1 transcription in human coronary artery endothelial cells.2010
- Author(s)
  Maekawa T, Takahashi N, Honda T, Yonezawa D, Miyashita H, Okui T, Tabeta K, Yamazaki K.
- Journal Title
  
  J Vasc Res. 47
  
  Pages: 346-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792116
[Journal Article] Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease.2010
- Author(s)
  Nakajima T, Honda T, Domon H, Okui T, Kajita K, Ito H, Takahashi N, Maekawa T, Tabeta K, Yamazaki K.
- Journal Title
  
  J Periodontal Res. 45
  
  Pages: 116-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792116
[Journal Article] Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease.2010
- Author(s)
  Nakajima T, Okui T, et al.
- Journal Title
  
  J Periodont Res 46
  
  Pages: 116-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792116
[Journal Article] Porphyromonas gingivalis Antigens and Interleukin-6 Stimulate the Production of Monocyte Chemoattractant Protein-1 via the Upregulation of Early Growth Response-1 Transcription in Human Coronary Artery Endothelial Cells.2009
- Author(s)
  Maekawa T, Okui T, et al.
- Journal Title
  
  J Vasc Res 47
  
  Pages: 346-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792116
[Journal Article] Characterization of CD4+ T-cell clones established from chronic inflammatory lesions2008
- Author(s)
  Okui T, Ito H, Honda T, Amanuma, Yoshie H, Yamazaki K
- Journal Title
  
  ral Microbiol Immunol 23(1)
  
  Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791609
[Journal Article] Elevated expression of IL-17 and IL-12 genes in chronic inflammatory periodontal disease2008
- Author(s)
  Honda T, Aoki Y, Takahashi N, Maekawa T, Nakajima T, Ito H, Tabata K, Okui T, Kajita K, Domon H, Yamazaki K
- Journal Title
  
  Clin Chim Acta 395(1-2)
  
  Pages: 137-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791609
[Journal Article] Quantitative messenger RNA expression of Toll-like receptors and interferon-alphal in gingivitis and periodontitis2007
- Author(s)
  Kajita K, Honda T, Amanuma R, Domon H, Okui T, Ito H, Yoshie, Tabata K, Nakajima T, Yamazaki K
- Journal Title
  
  Oral Microbiol Immunol 22(6)
  
  Pages: 398-402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] 歯周炎病変部におけるIL-17+FOXP3+T細胞の関与2011
- Author(s)
  奥井隆文
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-23792469
[Presentation] 歯周炎病変部におけるIL-17+FOXP3+ T細胞の関与2011
- Author(s)
  奥井隆文
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-23792469
[Presentation] Identification of IL-17+FOXP3+ T cells in periodontitis lesions2011
- Author(s)
  Takafumi Okui
- Organizer
  The 59th Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  広島国際会議場（広島市）
- Data Source
  KAKENHI-PROJECT-23792469
[Presentation] Identification of IL-17+FOXP3+ T cells in periodontitis lesions2011
- Author(s)
  Okui T
- Organizer
  The 59th Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  広島国際会議場(広島市)
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-23792469
[Presentation] SPT期活動性歯周ポケットに対するシタフロキサシン経口投与有用性の検討2010
- Author(s)
  奥井隆文
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡市民文化ホール
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21792116
[Presentation] SPT期活動性歯周ポケットに対するシタフロキサシン経口投与有用性の検討2010
- Author(s)
  奥井隆文, ら
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21792116
[Presentation] 歯周炎患者におけるPorphyromonas gingivalisに対する抗体価と高感度CRPの関連性2009
- Author(s)
  宮下博考, 奥井隆文, ら
- Organizer
  第52回秋季歯周病学会学術大会
- Place of Presentation
  宮崎市
- Year and Date
  2009-10-11
- Data Source
  KAKENHI-PROJECT-21792116
[Presentation] Lymphoid and inflammatory chemokine expression in chronic periodontitis lesoons2008
- Author(s)
  Nakajima T, Amanuma R, Aoki Y, Honda T, Okui T, Domon H, Kajimta K. Yamazaki K
- Organizer
  86^<th> General Session and Exhibition of International Association for Dental Research
- Place of Presentation
  Toronto, Canada
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] 歯周炎組織かた樹立したCD4^+T細胞ラインにおけるTh17関連分子の解析2008
- Author(s)
  奥井隆文、伊藤晴江、本田朋之、中島貴子、多部田康一、吉江弘正、山崎和久
- Organizer
  第51回日本歯周病学会秋季学術大会
- Place of Presentation
  四日市
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] 歯周炎組織における炎症性および恒常性維持ケモカインの発現バランス2008
- Author(s)
  中島貴子、天沼亮子、青木由香莉、本田朋之、奥井隆文、土門久哲、梶田桂子、高橋直紀。前川知樹、伊藤晴江、多部田康一、山崎和久
- Organizer
  第128回日本歯科保存学会春季学術大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] 歯周炎組織から樹立したCD 4^+T細胞ラインにおけるTh17関連分子の解析2008
- Author(s)
  奥井、伊藤、山崎、他。
- Organizer
  第51回秋季歯周病学会学術大会
- Place of Presentation
  四日市市
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] 歯周疾患が脂質代謝に及ぼす影響2008
- Author(s)
  中島貴子、本田朋之、奥井隆文、梶田桂子、土門久哲、高橋直紀、前川知樹、天沼亮子、伊藤晴江、多部田康一、山崎和久
- Organizer
  第21回日本歯科医学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] 歯周炎組織におけるTh17関連サイトカイン/マーカー遺伝子発現解析2008
- Author(s)
  本田朋之、青木由香莉、高橋直紀、前川知樹、中島貴子、伊藤春江、多部田康一、奥井隆文、梶田桂子、土門久哲、吉江弘正、山崎和久
- Organizer
  第51回日本歯周病学会秋季学術大会
- Place of Presentation
  四日市
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] 歯周炎におけるToll-like receptorsおよびinterferon-αの発現2007
- Author(s)
  梶田桂子、本田朋之、天沼亮子、土門久哲、奥井隆文、伊藤晴江、多部田康一、中島貴子、吉江弘正、山崎和久
- Organizer
  第50回日本歯周病学会春季学術大会
- Place of Presentation
  横須賀
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-19791609
[Presentation] Resveratrolは歯肉上皮細胞の炎症性応答を抑制する
- Author(s)
  奥井隆文，皆川高嘉，多部田康一，中島貴子，村上伸也，山崎和久
- Organizer
  第56回秋季日本歯周病学会学術大会
- Place of Presentation
  前橋市民文化会館（前橋市）
- Data Source
  KAKENHI-PROJECT-25463215
[Presentation] Anti-inflammatory effects of resveratrol in human gingival epithelial cells
- Author(s)
  Minagawa T, Okui T, Nakajima T, Tabeta K, Murakami S, Yamazaki K
- Organizer
  IADR-APR 2013
- Place of Presentation
  Plaza Athenee, Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-25463215
[Presentation] Resveratrolがヒト歯肉上皮細胞の炎症性応答に及ぼす影響
- Author(s)
  皆川高嘉，奥井隆文，中島貴子，多部田康一，村上伸也，山崎和久
- Organizer
  日本歯科保存学会2013年度春季学術大会（第138回）
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-25463215

1. ITO Harue (30397145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. HONDA Tomoyuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. NONAK Yukari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 土門久哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 中島貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 山崎和久

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

OKUI Takafumi 奥井 隆文

Research Projects

Research Products

Co-Researchers

歯周炎予防・治療におけるレスベラトロールの応用に向けた基礎的な研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of Treg-Th17 conversion induced by periodontopathicbacteria on osteoclastogenesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of periodontitis lesions focusing on a new T-cell subset, Th17.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of effector T cells on bone resorption in periodontal diseased lesons

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Resveratrol suppresses the inflammatory responses of human gingival epithelial cells in a SIRT1 independent manner2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of distinct T cell subsets in periodontitis - Studies from humans and rodent models.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased serum PCSK9 concentrations are associated with periodontal infection but do not correlate with LDL cholesterol concentration2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effects of systemic sitafloxacin on periodontal infection control in elderly patients2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The presence of IL-17^+/FOXP3^+ double-positive cells in periodontitis2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated antibody titers to Porphyromonas gingivalis as a possible predictor of ischemic vascular disease - results from the Tokamachi-Nakasato cohort study2011

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Effect of interleukin-17 on the expression of chemokines in gingival epithelial cells2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Porphyromonas gingivalis antigens and interleukin-6 stimulate the production of monocyte chemoattractant protein-1 via the upregulation of early growth response-1 transcription in human coronary artery endothelial cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease.2010

Author(s)

Journal Title

Data Source

[Journal Article] Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease.2010

Author(s)

Journal Title

Data Source

[Journal Article] Porphyromonas gingivalis Antigens and Interleukin-6 Stimulate the Production of Monocyte Chemoattractant Protein-1 via the Upregulation of Early Growth Response-1 Transcription in Human Coronary Artery Endothelial Cells.2009

Author(s)

Journal Title

Data Source

OKUI Takafumi 奥井隆文