Imanisi Takayuki 今西貴之

… Alternative Names

今西貴之イマニシタカユキ

Imanishi Takayuki 今西貴之

IMANISHI Takayuki 今西貴之

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Researcher Number	10513442
Affiliation (Current)	2025: 北里大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023: 北里大学, 医学部, 助教 2021 – 2022: 国立研究開発法人理化学研究所, 生命医科学研究センター, 上級研究員 2018: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2016 – 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 研究員 2013: 独立行政法人理化学研究所, 統合生命医科学研究センター, 研究員 2011 – 2012: 独立行政法人理化学研究所, 免疫シグナル研究グループ, 研究員 2010: 独立行政法人理化学研究所, 免疫シグナル研究グループ, 特別研究員
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related
Keywords	Principal Investigator T細胞 / mTOR / Th1 / 共刺激 / TCR / TLR / 加齢性疾患 / 加齢関連疾患 / 炎症 / インフラメージング … More / SASP / 老化 / シグナル伝達 / 免疫学 / 自然免疫 / 獲得免疫 / cGAMP / mTORC1 / I型インターフェロン / STING / サイトカイン / Th2 / エフェクターT細胞 / IL-2 / メモリーT細胞 / Th17 Less

T細胞の老化が生体におよぼす影響とその分子機構の解明Principal Investigator
- Principal Investigator
  
  今西貴之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kitasato University
  Institute of Physical and Chemical Research
Study of the regulation of T cell activation by cytosolic DNA sensor in T cellsPrincipal Investigator
- Principal Investigator
  
  Imanishi Takayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Institute of Physical and Chemical Research
Understanding of the molecular mechanism for nucleic acid sensing by T cellsPrincipal Investigator
- Principal Investigator
  
  IMANISHI Takayuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Institute of Physical and Chemical Research
Understanding of direct influence of pathogen-associated molecular patterns on T cell responsesPrincipal Investigator
- Principal Investigator
  
  IMANISHI Takayuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research

All 2024 2023 2022 2019 2018 2017 2016 2014 2013

All Journal Article Presentation Book Patent

[Book] 臨床免疫・アレルギー科2024
- Author(s)
  今西貴之
- Total Pages
  8
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21K07087
[Book] 臨床免疫・アレルギー科2018
- Author(s)
  今西　貴之
- Total Pages
  8
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16K08852
[Journal Article] RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-82023
- Author(s)
  Takayuki Imanishi, Midori Unno, Natsumi Yoneda, Yasutaka Motomura, Miho Mochizuki, Takaharu Sasaki, Manolis Pasparakis, Takashi Saito
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 4
- DOI
  10.1126/sciadv.add6097
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07087
[Journal Article] Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function2019
- Author(s)
  Imanishi Takayuki、Unno Midori、Kobayashi Wakana、Yoneda Natsumi、Matsuda Satoshi、Ikeda Kazutaka、Hoshii Takayuki、Hirao Atsushi、Miyake Kensuke、Barber Glen N、Arita Makoto、Ishii Ken J、Akira Shizuo、Saito Takashi
- Journal Title
  
  Life Science Alliance
  
  Volume: 2 Issue: 1 Pages: e201800282-e201800282
- DOI
  10.26508/lsa.201800282
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19576, KAKENHI-PUBLICLY-17H05638, KAKENHI-PUBLICLY-17H05806, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-18H02672, KAKENHI-PROJECT-16K08852, KAKENHI-PROJECT-17K19585, KAKENHI-PROJECT-17K19937, KAKENHI-PROJECT-16H06276
[Journal Article] Nucleic acid sensing by T cells initiates Th2 cell differentiation.2014
- Author(s)
  Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T
- Journal Title
  
  Nat Commun
  
  Volume: 10 Issue: 1 Pages: 3566-3566
- DOI
  10.1038/ncomms4566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24790489, KAKENHI-PROJECT-26293107, KAKENHI-PROJECT-26670236
[Journal Article] Nucleic acid sensing by T cells initiates Th2 cell differentiation2014
- Author(s)
  Takayuki Imanishi, Chitose Ishihara, Mohamed El Sherif Gadelhaq Badr, Akiko Hashimoto, Tane, Yayoi Kimura, Taro Kawai, Osamu Takeuchi, Ken J. Ishii, Shun, ichiro Taniguchi, Tetsuo Noda, Hisashi Hirano, Frank Brombacher, Glen N. Barber, Shizuo Akira, & Takashi Saito
- Journal Title
  
  NATURE COMMUNICATIONS
  
  Volume: 10 Pages: 1038-1038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790489
[Patent] 免疫細胞の制御技術2017
- Inventor(s)
  今西貴之、斉藤隆
- Industrial Property Rights Holder
  今西貴之、斉藤隆
- Industrial Property Rights Type
  特許
- Filing Date
  2017-02-17
- Data Source
  KAKENHI-PROJECT-16K08852
[Presentation] RIPK1 blocks T cell senescence mediated by RIPK1 and caspase-82024
- Author(s)
  今西貴之
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07087
[Presentation] RIPK1 による T 細胞の老化制御機構2023
- Author(s)
  今西貴之
- Organizer
  第 31 回東京免疫フォーラム
- Data Source
  KAKENHI-PROJECT-21K07087
[Presentation] T細胞による自然免疫認識と老化制御2023
- Author(s)
  今西貴之
- Organizer
  第30回内毒素・LPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07087
[Presentation] RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-82022
- Author(s)
  今西貴之
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07087
[Presentation] Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function2018
- Author(s)
  Takayuki Imanishi、Takashi Saito
- Organizer
  TOLL 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08852
[Presentation] Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function2018
- Author(s)
  Takayuki Imanishi、Takashi Saito
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08852
[Presentation] TCR-signals control STING-mediated type 1 IFN responses in T cells2017
- Author(s)
  今西貴之
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08852
[Presentation] T cell-intrinsic role of the cytosolic DNA-sensing for T cell function2016
- Author(s)
  今西貴之
- Organizer
  第16回国際免疫学会議
- Place of Presentation
  オーストラリア、メルボルン
- Year and Date
  2016-08-21
- Data Source
  KAKENHI-PROJECT-16K08852
[Presentation] STING activation in T cells induces cell growth inhibition and anti-viral response2016
- Author(s)
  今西貴之
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K08852
[Presentation] Nucleic acid-mediated T cell activation through a novel sensing mechanism induces Th2 responses2013
- Author(s)
  今西貴之　審良静男　斉藤隆　他
- Organizer
  第15回国際免疫学会議
- Place of Presentation
  イタリア・ミラノ
- Data Source
  KAKENHI-PROJECT-24790489
[Presentation] Nucleic acid - mediated T cell activation through a novel sensing mechanism induces Th2 responses2013
- Author(s)
  1.今西貴之審良静男斉藤隆
- Organizer
  第15回国際免疫学会議
- Place of Presentation
  イタリア・ミラノ
- Year and Date
  2013-08-26
- Data Source
  KAKENHI-PROJECT-24790489
[Presentation] Direct recognition of nucleic acids by T cells initiates Th2 cell differentiation2013
- Author(s)
  2.今西貴之審良静男斉藤隆
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉市幕張メッセ
- Year and Date
  2013-12-11
- Data Source
  KAKENHI-PROJECT-24790489

1. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 斉藤隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Imanisi Takayuki 今西 貴之

今西 貴之 イマニシ タカユキ

Imanishi Takayuki 今西 貴之

IMANISHI Takayuki 今西 貴之

Research Projects

Research Products

Co-Researchers

T細胞の老化が生体におよぼす影響とその分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of the regulation of T cell activation by cytosolic DNA sensor in T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Understanding of the molecular mechanism for nucleic acid sensing by T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Understanding of direct influence of pathogen-associated molecular patterns on T cell responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床免疫・アレルギー科2024

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床免疫・アレルギー科2018

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-82023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleic acid sensing by T cells initiates Th2 cell differentiation.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleic acid sensing by T cells initiates Th2 cell differentiation2014

Author(s)

Journal Title

Data Source

[Patent] 免疫細胞の制御技術2017

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] RIPK1 blocks T cell senescence mediated by RIPK1 and caspase-82024

Author(s)

Organizer

Data Source

[Presentation] RIPK1 による T 細胞の老化制御機構2023

Author(s)

Organizer

Data Source

[Presentation] T細胞による自然免疫認識と老化制御2023

Author(s)

Organizer

Data Source

[Presentation] RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-82022

Author(s)

Imanisi Takayuki 今西貴之

今西貴之イマニシタカユキ

Imanishi Takayuki 今西貴之

IMANISHI Takayuki 今西貴之