Kubota Kazuo 久保田一生

… Alternative Names

久保田一生クボタカズオ

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Researcher Number	10526940
Other IDs
Affiliation (Current)	2025: 岐阜大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2023: 岐阜大学, 医学部附属病院, 講師 2020 – 2022: 岐阜大学, 医学部附属病院, 助教 2015 – 2017: 岐阜大学, 医学部附属病院, 助教 2013 – 2014: 岐阜大学, 医学(系)研究科(研究院), 非常勤講師
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator ペルオキシソーム病 / 極長鎖脂肪酸 / ゼブラフィッシュ / DBP欠損症 / 遺伝学 / アスパラギン合成酵素 / アスパラギン合成酵素欠損症 / Toll様受容体 / 自然免疫 Except Principal Investigator 脳機能 … More / 認知機能 / MRI / 機能的MRI / 拡散テンソルMRI / 筋ジストロフィー / 発達障害 / 知的障害 Less

ぺルオキシソーム病モデルフィッシュを用いた神経変性疾患の重症度予測と治療法の開発Principal Investigator
- Principal Investigator
  
  久保田一生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gifu University
先進的MRI解析によるDuchenne型筋ジストロフィーの脳構造・機能異常の解明
- Principal Investigator
  
  夏目淳
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
Development of diagnostic screening method and treatment for asparagine synthetase deficiencyPrincipal Investigator
- Principal Investigator
  
  Kubota Kazuo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
The analysis of TLR10 signaling pathway for elucidating the pathogenesis of allergic diseases.Principal Investigator
- Principal Investigator
  
  Kubota Kazuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University

All 2023 2022 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] The first report of Japanese patients with asparagine synthetase deficiency2017
- Author(s)
  Yamamoto T, Endo W, Ohnishi H, Kubota K, Kawamoto N, Inui T, Imamura A, Takanashi JI, Shiina M, Saitsu H, Ogata K, Matsumoto N, Haginoya K, Fukao T
- Journal Title
  
  Brain Development
  
  Volume: 39 Issue: 3 Pages: 236-242
- DOI
  10.1016/j.braindev.2016.09.010
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118005, KAKENHI-PROJECT-16H05160, KAKENHI-PROJECT-26330331, KAKENHI-PROJECT-16K19637, KAKENHI-PROJECT-16H03293
[Journal Article] The long-term health impact and potential predictors of cardiopulmonary arrest in patients with childhood-onset psychomotor impairments.2016
- Author(s)
  Kubota K, Shimizu-Motohashi Y, Saito T, Akatsuka S, Takeshita E, Ishiyama A, Komaki H, Nakagawa E, Sugai K, Sasaki M.
- Journal Title
  
  Brain Dev.
  
  Volume: 38 Issue: 4 Pages: 392-398
- DOI
  10.1016/j.braindev.2015.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860854
[Journal Article] De novo KIF1A mutations cause intellectual deficit, cerebellar atrophy, lower limb spasticity and visual disturbance.2015
- Author(s)
  Ohba, C., K. Haginoya, H. Osaka, K. Kubota, A. Ishiyama, T. Hiraide, H. Komaki, M. Sasaki, S. Miyatake, M. Nakashima, Y. Tsurusaki, N. Miyake, F. Tanaka, H. Saitsu, and N. Matsumoto
- Journal Title
  
  J Hum Genet
  
  Volume: 60 Issue: 12 Pages: 739-42
- DOI
  10.1038/jhg.2015.108
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461549, KAKENHI-PROJECT-15K19660, KAKENHI-PROJECT-25860854, KAKENHI-PROJECT-25293235
[Journal Article] Brain magnetic resonance imaging findings and auditory brainstem response in a child with spastic paraplegia 2 due to a PLP1 splice site mutation.2015
- Author(s)
  Kubota K, Saito Y, Ohba C, Saitsu H, Fukuyama T, Ishiyama A, Saito T, Komaki H, Nakagawa E, Sugai K, Sasaki M, Matsumoto N.
- Journal Title
  
  Brain Dev.
  
  Volume: 37 Issue: 1 Pages: 158-162
- DOI
  10.1016/j.braindev.2014.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860854
[Journal Article] 注意欠如・多動性障害における脳波異常と薬物治療の検討.2015
- Author(s)
  久保田一生, 仲村貞郎, 稲垣真澄, 中川栄二.
- Journal Title
  
  小児科臨床
  
  Volume: 68 Pages: 2083-2088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860854
[Journal Article] Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia.2014
- Author(s)
  Kubota K, Ozeki M, Hori T, Kanda K, Funato M, Asano T, Fukao T, Kondo N.
- Journal Title
  
  Pediatr Int.
  
  Volume: 56 Issue: 4 Pages: 37-40
- DOI
  10.1111/ped.12384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461587, KAKENHI-PROJECT-25860854
[Journal Article] Clinical and genetic characterization of Japanese sporadic cases of periodic Fever, aphthous stomatitis, pharyngitis and adenitis syndrome from a single medical center in Japan.2014
- Author(s)
  Kubota K, Ohnishi H, Teramoto T, Kawamoto N, Kasahara K, Ohara O, Kondo N.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 34 Issue: 5 Pages: 584-593
- DOI
  10.1007/s10875-014-0043-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860854, KAKENHI-PROJECT-26461576
[Journal Article] Functional assessment of the mutational effects of human IRAK4 and MyD88 genes.2014
- Author(s)
  Yamamoto T, Tsutsumi N, Tochio H, Ohnishi H, Kubota K, Kato Z, Shirakawa M, Kondo N.
- Journal Title
  
  Mol Immunol
  
  Volume: 58(1) Issue: 1 Pages: 66-76
- DOI
  10.1016/j.molimm.2013.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23115004, KAKENHI-PROJECT-23791161, KAKENHI-PUBLICLY-25112514, KAKENHI-PROJECT-25860854
[Presentation] 安静時機能的MRIを用いたデュシェンヌおよびベッカー型筋ジストロフィーの脳機能的ネットワーク解析2023
- Author(s)
  川口将宏、夏目　淳、伊藤祐史、山本啓之、中田智彦、竹内智哉、久保田一生、服部文子、丸山幸一、久保田哲夫、越知信彦、舩戸道徳、城所博之
- Organizer
  第65回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08204
[Presentation] ３DT1強調画像を用いたデュシェンヌおよびベッカー型筋ジストロフィーの脳画像解析2022
- Author(s)
  川口将宏、夏目淳、山本啓之、中田智彦、竹内智哉、久保田一生、服部文子、丸山幸一、久保田哲夫、越知信彦、舩戸道徳、城所博之
- Organizer
  第64回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08204
[Presentation] Asparagine Synthetase Deficiency: The First Japanese Case Report and Review of Literature.2017
- Author(s)
  Yamamoto T., Endo W., Ohnishi H., Kubota K., Kawamoto N., Inui T., Imamura A., Takanashi J. I., Shiina M., Saitsu H., Ogata K., Matsumoto N., Haginoya K., Fukao T.
- Organizer
  AOCCN2017 (14th Asia Oceanian Congress Child Neurology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19637
[Presentation] 進行性の小頭症、重度の精神運動発達遅滞と難治性てんかんを認めアスパラギン合成酵素欠損症と診断した一例2016
- Author(s)
  久保田一生, 山本崇裕, 川本典生, 大西秀典, 今村淳, 才津浩智, 松本直通, 深尾敏幸
- Organizer
  第58回日本先天代謝異常学会総会
- Place of Presentation
  東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K19637
[Presentation] Whole-exome解析により診断したアスパラギン合成酵素欠損症の変異機能解析2016
- Author(s)
  山本崇裕, 大西秀典, 久保田一生, 西村紗織, 笠原由貴子, 折居建治, 今村淳, 才津浩智, 松本直通, 深尾敏幸
- Organizer
  第58回日本小児神経学会学術集会
- Place of Presentation
  東京
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PROJECT-16K19637

1. 夏目淳 (60422771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 城所博之 (20647466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 服部文子 (80444975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 下澤伸行 (00240797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 高島茂雄 (50537610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OZEKI Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ISHI Shunsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 宮武聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 緒方一博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 松本直通

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 杤尾豪人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubota Kazuo 久保田 一生

久保田 一生 クボタ カズオ

Research Projects

Research Products

Co-Researchers

ぺルオキシソーム病モデルフィッシュを用いた神経変性疾患の重症度予測と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

先進的MRI解析によるDuchenne型筋ジストロフィーの脳構造・機能異常の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of diagnostic screening method and treatment for asparagine synthetase deficiencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of TLR10 signaling pathway for elucidating the pathogenesis of allergic diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The first report of Japanese patients with asparagine synthetase deficiency2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The long-term health impact and potential predictors of cardiopulmonary arrest in patients with childhood-onset psychomotor impairments.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] De novo KIF1A mutations cause intellectual deficit, cerebellar atrophy, lower limb spasticity and visual disturbance.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Brain magnetic resonance imaging findings and auditory brainstem response in a child with spastic paraplegia 2 due to a PLP1 splice site mutation.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 注意欠如・多動性障害における脳波異常と薬物治療の検討.2015

Author(s)

Journal Title

Data Source

[Journal Article] Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and genetic characterization of Japanese sporadic cases of periodic Fever, aphthous stomatitis, pharyngitis and adenitis syndrome from a single medical center in Japan.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional assessment of the mutational effects of human IRAK4 and MyD88 genes.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 安静時機能的MRIを用いたデュシェンヌおよびベッカー型筋ジストロフィーの脳機能的ネットワーク解析2023

Author(s)

Organizer

Data Source

[Presentation] ３DT1強調画像を用いたデュシェンヌおよびベッカー型筋ジストロフィーの脳画像解析2022

Author(s)

Organizer

Data Source

[Presentation] Asparagine Synthetase Deficiency: The First Japanese Case Report and Review of Literature.2017

Author(s)

Organizer

Data Source

Kubota Kazuo 久保田一生

久保田一生クボタカズオ