NOMIYAMA Takashi 野見山崇

Researcher Number	10532559
Other IDs	https://orcid.org/0000-0001-7040-1334
Affiliation (Current)	2025: 順天堂大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022: 順天堂大学, 医学部, 教授 2020 – 2021: 国際医療福祉大学, 国際医療福祉大学市川病院, 教授 2017 – 2019: 福岡大学, 医学部, 准教授 2013: 福岡大学, 医学部, 准教授 2009 – 2010: Juntendo University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Endocrinology
Keywords	Principal Investigator GLP-1 / 糖尿病 / p27Kip1 / SKP2 / Cell cycle / Cancer / 癌 / GLP-1受容体作動薬 / 乳癌 / メトホルミン … More / GLP-1受容体 / 細胞周期 / 前立腺癌 / 血管平滑筋細胞増殖 / 血糖変動 / 新生内膜形成 / 血管平滑筋増殖 / 糖質代謝異常 / エネルギー … More Except Principal Investigator アンドロゲン / 生活習慣病 / アドロゲン / LOH / メタボリックシンドローム / LOH症候群 / 前立腺癌 / テストステロン / 選択的アンドロゲン受容体修飾剤 / androgen receptor / obesity / high fat diet / SARM Less

GLP-1 receptor expression in cancer cellsPrincipal Investigator
- Principal Investigator
  
  Nomiyama Takashi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Juntendo University
  International University of Health and Welfare
  Fukuoka University
Comprehensive studies of androgen and SARM as a background of onset or treatment of life-related diseases
- Principal Investigator
  
  Yanase Toshihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Fukuoka University
Research on a novel selective androgen receptor modulator, S42 for the development of life-related drug.
- Principal Investigator
  
  YANASE Toshihiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Fukuoka University
Investigation of vascular smooth muscle proliferation by glucose fluctuationPrincipal Investigator
- Principal Investigator
  
  NOMIYAMA Takashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University

All 2021 2020 2018 2017 2016 2015 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Combined treatment with glucagon-like peptide-1 receptor agonist exendin-4 and metformin attenuates breast cancer growth.2021
- Author(s)
  Tanaka Y, Iwaya C, Kawanami T, Hamaguchi Y, Horikawa T, Shigeoka T, Yanase T, Kawanami D, Nomiyama T.
- Journal Title
  
  Diabetology International
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-18K08532
[Journal Article] Activation of overexpressed GLP-1R attenuates prostate cancer growth by inhibiting cell cycle progression2020
- Author(s)
  Toru Shigeoka, Takashi Nomiyama, Takako Kawanami, Yuriko Hamaguchi, Tsuyoshi Horikawa, Tomoko Tanaka, Shinichiro Irie, Ryoko Motonaga, Nobuya Hamanoue, Makito Tanabe, Kazuki Nabeshima, Masatoshi Tanaka, Toshihiko Yanase, Daiji Kawanami
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: NA Issue: 5 Pages: 1137-1149
- DOI
  10.1111/jdi.13247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08532
[Journal Article] Selective Androgen Receptor Modulator S42 Suppresses Prostate Cancer Cell Proliferation.2018
- Author(s)
  Kawanami, T., Tanaka, T., Hamaguchi, Y., Nomiyama, T., Nawata, H., and Yanase, T.
- Journal Title
  
  Endocrinology
  
  Volume: 159 Issue: 4 Pages: 1774-1792
- DOI
  10.1210/en.2018-00099
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09815, KAKENHI-PROJECT-15H04854
[Journal Article] Prescription of oral hypoglycemic agents for patients with type 2 diabetes mellitus: A retrospective cohort study using a Japanese hospital database.2017
- Author(s)
  Tanabe, M., Motonaga, R., Terawaki, Y., Nomiyama, T., and Yanase, T.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 8 Issue: 2 Pages: 227-234
- DOI
  10.1111/jdi.12567
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09815, KAKENHI-PROJECT-15H04854
[Journal Article] Impact of metabolic disorders on prostate cancer growth: Androgen and insulin resistance perspectives.2017
- Author(s)
  Yanase, T., Kawanami, T., Tanaka, T., Tanabe, M., and Nomiyama, T.
- Journal Title
  
  Reprod Med Biol
  
  Volume: 16 Issue: 3 Pages: 252-257
- DOI
  10.1002/rmb2.12039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09815, KAKENHI-PROJECT-15H04854
[Journal Article] Postpartum hypothalamic adrenal insufficiency with remission: A rare case2017
- Author(s)
  Akehi, Y., Hashimoto, Y., Meren, J., Tanabe, M., Nomiyama, T., and Yanase, T.
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 2 Pages: 157-162
- DOI
  10.1507/endocrj.EJ16-0066
- NAID
  130005397091
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09815, KAKENHI-PROJECT-15H04854
[Journal Article] A higher score on the Aging Males’ Symptoms scale is associated with insulin resistance in middle-aged men2017
- Author(s)
  Hamanoue, N., Tanabe, M., Tanaka, T., Akehi, Y., Murakami, J., Nomiyama, T., and Yanase, T.
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 5 Pages: 521-530
- DOI
  10.1507/endocrj.EJ16-0619
- NAID
  130005682812
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09815, KAKENHI-PROJECT-15H04854
[Journal Article] Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-kappaB Activation.2017
- Author(s)
  Iwaya, C., Nomiyama, T., Komatsu, S., Kawanami, T., Tsutsumi, Y., Hamaguchi, Y., Horikawa, T., Yoshinaga, Y., Yamashita, S., Tanaka, T., et al.
- Journal Title
  
  Endocrinology
  
  Volume: 158 Issue: 12 Pages: 4218-4232
- DOI
  10.1210/en.2017-00461
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09815, KAKENHI-PROJECT-15H04854
[Journal Article] Augmented GH secretion and Stat3 phosphorylation in an aryl hydrocarbon receptor interacting protein (AIP)-disrupted somatotroph cell line.2016
- Author(s)
  Fukuda T, Tanaka T, Hamaguchi Y, Kawanami T, Nomiyama T, Yanase T
- Journal Title
  
  PLOS ONE
  
  Volume: 11(10) Issue: 10 Pages: e0164131-e0164131
- DOI
  10.1371/journal.pone.0164131
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04854, KAKENHI-PROJECT-16K09815
[Journal Article] Efficacy of dipeptidyl peptidase-4 inhibitor linagliptin in patients with type 2 diabetes undergoing hemodialysis.2015
- Author(s)
  Terawaki Y, Nomiyama T, Takahashi H, Tsutsumi Y, Murase K, Nagaishi R, Tanabe M, Kudo T, Kobayashi K, Yasuno T, Nakashima H, Yanase T.
- Journal Title
  
  Diabetol Metab Syndr.
  
  Volume: 7 Issue: 1 Pages: 44-44
- DOI
  10.1186/s13098-015-0043-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04854
[Journal Article] Total testosterone is the most valuable indicator of metabolic syndrome among various testosterone values in middle-aged Japanese men2015
- Author(s)
  Tanabe M, Akehi Y, Nomiyama T, Murakami J, Yanase T.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 2 Pages: 123-132
- DOI
  10.1507/endocrj.EJ14-0313
- NAID
  130004700286
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04854
[Journal Article] Reduced vascular events in type 2 diabetes by biguanide relative to sulfonylurea: study in a Japanese Hospital Database.2015
- Author(s)
  Tanabe M, Nomiyama T, Motonaga R, Murase K, Yanase T.
- Journal Title
  
  BMC Endocr Disord.
  
  Volume: 15 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12902-015-0045-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04854
[Journal Article] Combined treatment with Extendin-4 and metoformin attenuates prostate cancer growth.2015
- Author(s)
  Tsutumi Y, Nomiyama T, Kawanami T, Hamaguchi Y, Tanaka T, Murase K, Motonaga R, Tanabe M, Yanase T.
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 10 Pages: e0139709-e0139709
- DOI
  10.1371/journal.pone.0139709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04854
[Journal Article] Prevalence and clinical characteristics of primary aldosteronism in Japanese patients with type 2 diabetes mellitus and hypertension.2013
- Author(s)
  Murase K., Nagaishi R., Takenoshita H., Nomiyama T., Akehi Y., Yanase T.
- Journal Title
  
  Endocr J
  
  Volume: 60 Pages: 967-976
- NAID
  10031195766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] Proposed diagnostic criteria for subclinical Cushing's syndrome associated with adrenal incidentaloma2013
- Author(s)
  Akehi Y, Kawate H, Murase K, Nagaishi R, Nomiyama T, Nomura M, Takayanagi R, Yanase T
- Journal Title
  
  Endocrine J
  
  Volume: 60(7) Pages: 903-912
- NAID
  10031195759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] 性腺機能低下症とその治療 : 男性の性腺機能低下症男性更年期(LOH)と生活習慣病2013
- Author(s)
  柳瀬敏彦, 村瀬邦崇, 野見山崇
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 36 Pages: 422-428
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] Proposed diagnostic criteria for subclinical Cushing's syndrome associated with adrenal incidentaloma.2013
- Author(s)
  Akehi Y., Kawate H., Murase K., Nagaishi R., Nomiyama T., Nomura M., Takayanagi R., Yanase T.
- Journal Title
  
  Endocr J
  
  Volume: 60 Pages: 903-912
- NAID
  10031195759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] Prevalence and clinical characteristics of primary aldosteronism in Japanese patients with type 2 diabetes mellitus and hypertension2013
- Author(s)
  Murase K, Nagaishi R, Takenoshita H, Nomiyama T, Akehi Y, Yanase T
- Journal Title
  
  Endocr J
  
  Volume: 60(8) Pages: 967-76
- NAID
  10031195766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] 【性腺機能低下症とその治療】男性の性腺機能低下症　男性更年期(LOH)と生活習慣病.2013
- Author(s)
  柳瀬敏彦、村瀬邦崇、野見山　崇
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 36 Pages: 422-428
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] 前立腺癌と糖代謝 : アンドロゲンとインスリンの観点から2012
- Author(s)
  柳瀬敏彦, 野見山崇
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 35 (3) Pages: 270-274
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] ステロイドホルモンと脂質代謝 : テストステロンと脂質代謝-late-onset hypogonadism (LOH)を含めて2012
- Author(s)
  柳瀬敏彦, 村瀬邦崇, 明比祐子, 野見山崇
- Journal Title
  
  The Lipid
  
  Volume: 23 Pages: 54-59
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] Contributing factors related to efficacy of the dipeptidyl peptidase-4 inhibitor sitagliptin in Japanese patients with type 2 diabetes2012
- Author(s)
  Nomiyama T, Akehi Y, Takenoshita H, Nagaishi R, Terawaki Y, Nagasako H, Kudo T, Kodera T, Kobayashi K, Urata H, Yanase T; members of CHAT.
- Journal Title
  
  Diabetes Res Clin Pract.
  
  Volume: 95 Issue: 2 Pages: e27-e28
- DOI
  10.1016/j.diabres.2011.08.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] 高齢者の男性医学 : テストステロンと脂質, 糖代謝, 肥満, 動脈硬化2012
- Author(s)
  柳瀬敏彦, 永石綾子, 明比祐子, 野見山崇
- Journal Title
  
  Geriatric Medicine
  
  Volume: 50 Pages: 449-454
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] Changes Through the Use of Delivered Meals and Dietary Counseling in a Single-Blind Study: the STYLIST Study2012
- Author(s)
  Noda K, Zhang B, Iwatata A, Nishikawa H, Ogawa M, Nomiyama T, Miura S, Sakou H, Matsuo K, Yahiro E, Yanase T, Saku K
- Journal Title
  
  Circulaion J
  
  Volume: 76 Pages: 1335-1344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injury.2011
- Author(s)
  後藤広昌、野見山崇
- Journal Title
  
  Biochem Biophys Res Commun. 405
  
  Pages: 79-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790883
[Journal Article] 「サルコペニアの診かた」アンドロゲンとサルコペニア2011
- Author(s)
  野見山崇, 村瀬邦崇, 田中智子, 柳瀬敏彦
- Journal Title
  
  Modern Medicine
  
  Volume: 31 Pages: 1370-1373
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] 男性更年期障害 : 診療の現状と基盤的臨床・基礎研究の進展2011
- Author(s)
  柳瀬敏彦, 村瀬邦崇, 田中智子, 野見山崇, 明比祐子
- Journal Title
  
  Medical Science Digest
  
  Volume: 37 Pages: 102-105
- Data Source
  KAKENHI-PROJECT-23390248
[Journal Article] 男性更年期障害:診療の現状と基盤的臨床・基礎研究の進展2011
- Author(s)
  柳瀬敏彦、村瀬邦崇、田中智子、野見山崇、明比祐子
- Journal Title
  
  Medical Science Digest (MSD)
  
  Volume: 37 Pages: 102-105
- Data Source
  KAKENHI-PROJECT-23390248
[Presentation] アンドロゲン受容体作動薬S42の前立腺癌細胞増殖に対する影響2017
- Author(s)
  川波賢子、田中智子、Liu Min、野見山崇、名和田新、柳瀬敏彦
- Organizer
  第90回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04854
[Presentation] GLP-1受容体作動薬(Exendin-4)は血管障害後の新生内膜形成を抑制する2010
- Author(s)
  野見山崇
- Organizer
  日本動脈硬化学会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21790883

1. YANASE Toshihiko (30239818)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
2. TANAKA Tomoko (10380528)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. MURASE Kunitaka (30712517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. TANABE Makito (60707305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

NOMIYAMA Takashi 野見山 崇

Research Projects

Research Products

Co-Researchers

GLP-1 receptor expression in cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive studies of androgen and SARM as a background of onset or treatment of life-related diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on a novel selective androgen receptor modulator, S42 for the development of life-related drug.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of vascular smooth muscle proliferation by glucose fluctuationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Combined treatment with glucagon-like peptide-1 receptor agonist exendin-4 and metformin attenuates breast cancer growth.2021

Author(s)

Journal Title

Data Source

[Journal Article] Activation of overexpressed GLP-1R attenuates prostate cancer growth by inhibiting cell cycle progression2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selective Androgen Receptor Modulator S42 Suppresses Prostate Cancer Cell Proliferation.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prescription of oral hypoglycemic agents for patients with type 2 diabetes mellitus: A retrospective cohort study using a Japanese hospital database.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of metabolic disorders on prostate cancer growth: Androgen and insulin resistance perspectives.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Postpartum hypothalamic adrenal insufficiency with remission: A rare case2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] A higher score on the Aging Males&rsquo; Symptoms scale is associated with insulin resistance in middle-aged men2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-kappaB Activation.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Augmented GH secretion and Stat3 phosphorylation in an aryl hydrocarbon receptor interacting protein (AIP)-disrupted somatotroph cell line.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of dipeptidyl peptidase-4 inhibitor linagliptin in patients with type 2 diabetes undergoing hemodialysis.2015

Author(s)

NOMIYAMA Takashi 野見山崇

[Journal Article] A higher score on the Aging Males’ Symptoms scale is associated with insulin resistance in middle-aged men2017

[Journal Article] 【性腺機能低下症とその治療】男性の性腺機能低下症　男性更年期(LOH)と生活習慣病.2013