Ohno Yoshinori 大野芳典

… Alternative Names

OHNO Yoshinori 大野芳典

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Researcher Number	10548986
Other IDs
Affiliation (Current)	2025: 福岡大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 福岡大学, 医学部, 講師 2011 – 2018: 広島大学, 原爆放射線医科学研究所, 助教 2010: 広島大学, 医歯薬学総合研究所, 助教 2010: 広島大学, 医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Hematology / Risk sciences of radiation and chemicals Except Principal Investigator General anatomy (including histology/embryology) / Regenerative medicine / Basic Section 54010:Hematology and medical oncology-related / Risk sciences of radiation and chemicals / Hematology / Stem cell biology and medical science
Keywords	Principal Investigator 造血幹細胞 / Geminin / 白血病幹細胞 / 造血システム / 細胞運命 / 放射線防護 / 低線量率放射線被ばく / ROS / ミトコンドリア / 低線量率放射線 … More / ユビキチン / MLL-AF9 / Hox / E2F / Mll-Af9 / Hoxa9 … More Except Principal Investigator Geminin / 造血幹細胞 / 自己複製 / 再生医学 / 細胞周期 / ポリコーム複合体 / 心筋 / ポリコーム遺伝子群 / ユビキチン化 / ポリコーム複合体1 / 分化 / 染色体分配 / ポリコーム複合体１ / ZFAT / 低線量被ばく / 低線量率放射線被ばく / 多分化能 / 長期骨髄再構築能 / 低線量放射線被ばく / 心臓幹細胞 / 心筋分裂 / 幹細胞 / 細胞分化 / 細胞増殖 / 維持 / 心筋維持 / 心臓発生 / 幹細胞生物学 / Hoxa9/Hoxb4 / Hox / ポリコーム / 造血幹細胞移植療法 / Hoxb4 / ES細胞 / iPS細胞 / iPS 細胞 / 造血幹細胞移植学 / DMA複製制御 / DNA複製制御 / 発生・分化 Less

The molecular crosstalk between ZFAT and Geminin in the regulation of hematopoietic stem cell proliferation and differentiation.
- Principal Investigator
  
  Yasunaga Shin'ichiro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukuoka University
Development of protection method against low dose rate radiation exposure of hematopoietic systemPrincipal Investigator
- Principal Investigator
  
  Ohio Yoshinori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Fukuoka University
  Hiroshima University
Molecular and cellular analyses of hematopoietic stem cell damage induced by low dose-rate irradiation
- Principal Investigator
  
  Takihara Yoshihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Hiroshima University
Detection of cell-cycling cardiac muscle cells by visualizing Geminin, and regeneration of cardiac muscle cells
- Principal Investigator
  
  Takihara Yoshihiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Hiroshima University
Basic research on regulatory system for self-renewal and differentiation of hematopoietic stem cells for the purpose of future application to regenerative medicine
- Principal Investigator
  
  YASUNAGA Shin'ichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Fukuoka University
  Hiroshima University
Analysis for molecular role of Geminin in hematopoietic and leukemia stem cellPrincipal Investigator
- Principal Investigator
  
  Ohno Yoshinori
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Molecular role for Geminin in maintaining cardiac muscles
- Principal Investigator
  
  TAKIHARA Yoshihiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Hiroshima University
Analysis of the molecular function of Geminin in leukemogenesisPrincipal Investigator
- Principal Investigator
  
  OHNO Yoshinori
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Analysis of regulatory mechanism for activity of hematopoietic stem cell mediated by regulation of Geminin protein
- Principal Investigator
  
  YASUNAGA Shin'ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Hiroshima University
Induction of hematopoietic stemcells from iPS cells and the molecular basis in the induction
- Principal Investigator
  
  TAKIHARA Yoshihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Analysis of Hematopoietic stem cell regulation through Polycomb-group complex 1
- Principal Investigator
  
  OHTSUBO Motoaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Stem cell biology and medical science
- Research Institution
  Beppu University
  Hiroshima University

All 2023 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 血液フロンティア・がん幹細胞研究の新たな展開・幹細胞における細胞周期制御2012
- Author(s)
  瀧原義宏、安永晋一郎、大野芳典、大坪素秋
- Total Pages
  11
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-21602004
[Book] 血液フロンティア・がん幹細胞研究の新たな展開・幹細胞における細胞周期制御2012
- Author(s)
  瀧原義宏,安永晋一郎,大野芳典,大坪素秋
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-21602004
[Journal Article] 造血幹細胞活性に対する低線量被ばくの影響．2020
- Author(s)
  大野芳典、竹立恭子、郭芸、菅野雅元、白須直人、安永晋一郎、大坪素秋、瀧原義弘．
- Journal Title
  
  広島医学
  
  Volume: 73 Pages: 218-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08828
[Journal Article] 低線量率放射線被ばくの造血システムに対する放射線障害の解析2018
- Author(s)
  大野　芳典
- Journal Title
  
  長崎医学会雑誌
  
  Volume: 93 Pages: 334-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00552
[Journal Article] 骨髄の組織反応 (特集放射線生物学と放射線防護を繋ぐ組織反応研究)2017
- Author(s)
  大野　芳典、竹立　恭子、白須　直人、安永　晋一郎、瀧原　義宏
- Journal Title
  
  放射線生物研究
  
  Volume: 52(4) Pages: 336-349
- NAID
  40021447913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00552
[Journal Article] 骨髄の組織反応2017
- Author(s)
  大野　芳典、竹立　恭子、白須　直人、安永　晋一郎、瀧原　義宏
- Journal Title
  
  放射線生物研究
  
  Volume: 52(4) Pages: 336-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02955
[Journal Article] Manipulation of cell cycle and chromatin configuration by means of cell-penetrating Geminin.2016
- Author(s)
  Ohno Y., Suzuki-Takedachi K., Yasunaga S., Kurogi T., Santo M., Masuhiro Y., Hanazawa S., Ohtsubo M., Naka K. & Takihara Y.
- Journal Title
  
  PLoS ONE
  
  Volume: 11(5) Issue: 5 Pages: 1-14
- DOI
  10.1371/journal.pone.0155558
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26501004, KAKENHI-PROJECT-15K15018
[Journal Article] Role of Geminin in cell fate determination of hematopoietic stem cells (HSCs)2016
- Author(s)
  YASUNAGA, S., OHNO, Y., SHIRASU, N., ZHANG, B., SUZUKI-TAKEDACHI, K., OHTSUBO, M. & TAKIHARA, Y.
- Journal Title
  
  Int J Hematol
  
  Volume: 104 Issue: 3 Pages: 324-9
- DOI
  10.1007/s12185-016-2060-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460664, KAKENHI-PROJECT-26501004
[Journal Article] Significance of ACADM mutations identified from newborn screening of MCAD deficiency in Japan2016
- Author(s)
  Keiichi Hara, Go Tajima, Satoshi Okada, Miyuki Tsumura, Reiko Kagawa, Kenichiro Shirao, Yoshinori Ohno, Shin'ichiro Yasunaga, Motoaki Ohtsubo, Ikue Hata, Nobuo Sakura, Yosuke Shigematsu, Yoshihiro Takihara, Masao Kobayashi
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: 118 Issue: 1 Pages: 9-14
- DOI
  10.1016/j.ymgme.2015.12.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461526, KAKENHI-PROJECT-26501004, KAKENHI-PROJECT-15K21189
[Journal Article] Gemininによる白血病幹細胞の制御2015
- Author(s)
  安永晋一郎、大野芳典、瀧原義宏
- Journal Title
  
  日本臨床
  
  Volume: 73(5) Pages: 800-805
- Data Source
  KAKENHI-PROJECT-26501004
[Journal Article] Simple diagnosis of STAT1 gain-of-function alleles in patients with chronic mucocutaneous candidiasis.2014
- Author(s)
  Mizoguchi Y, Tsumura M, Okada S, Hirata O, Minegishi S, Imai K, Hyakuna N, Muramatsu H, Kojima S, Ozaki Y, Imai T, Takeda S, Okazaki T, Ito T, Yasunaga S, Takihara Y, Bryant VL, Kong XF, Cypowyj S, Boisson-Dupuis S, Puel A, Casanova JL, Morio T, Kobayashi M.
- Journal Title
  
  J. Leukoc. Biol.
  
  Volume: 95 Issue: 4 Pages: 667-76
- DOI
  10.1189/jlb.0513250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390270, KAKENHI-PROJECT-23618008, KAKENHI-PUBLICLY-25118717, KAKENHI-PUBLICLY-25130708, KAKENHI-PROJECT-25293231, KAKENHI-PROJECT-25293232, KAKENHI-PROJECT-25713039, KAKENHI-PROJECT-25870468, KAKENHI-PROJECT-26501004, KAKENHI-PROJECT-26670501, KAKENHI-PROJECT-26670502
[Journal Article] Transcription of the Geminin gene is regulated loop2014
- Author(s)
  Ohno Y, Saeki K, Yasunaga S, Kurogi T, Suzuki-Takedachi K, Shirai M, Mihara K, Yoshida K, Voncken JW, Ohtsubo M, Takihara Y
- Journal Title
  
  Mol Biol Cell
  
  Volume: 25(8) Pages: 1374-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790976
[Journal Article] Transcription of the Geminin gene is regulated by a negative-feedback loop.2014
- Author(s)
  Ohno, Y., Saeki, K., Yasunaga, S., Kurogi. T., Suzuki-Takedachi, K., Shirai, M., Mihara K., Yoshida, K., Voncken J. W, Ohtsubo, M. & Takihara Y.
- Journal Title
  
  Mol. Biol. Cel
  
  Volume: 25(8) Issue: 8 Pages: 1374-1383
- DOI
  10.1091/mbc.e13-09-0534
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23618008, KAKENHI-PROJECT-24591595, KAKENHI-PROJECT-24790976, KAKENHI-PUBLICLY-25118717, KAKENHI-PUBLICLY-25130708, KAKENHI-PROJECT-25670096, KAKENHI-PROJECT-26501004
[Journal Article] Hoxa9 transduction induces mouse hematopoietic stem and progenitor cell activity through direct down-regulation of Geminin.2013
- Author(s)
  Ohno, Y., Yasunaga, S., Janmohamed, S., Ohtubo, M., Mihara, K., Iscove, N., Takihara, Y.
- Journal Title
  
  PLoS ONE
  
  Volume: 8(1) Issue: 1 Pages: e53161-e53161
- DOI
  10.1371/journal.pone.0053161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390195, KAKENHI-PROJECT-23618008, KAKENHI-PROJECT-23659096, KAKENHI-PROJECT-24790976, KAKENHI-PUBLICLY-25130708, KAKENHI-PUBLICLY-23118519, KAKENHI-PUBLICLY-23130511
[Journal Article] Scmh1 has E3 ubiquitin ligase activity for Geminin and histone H2A and regulates Geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4.2013
- Author(s)
  Yasunaga, S., Ohtsubo, M., Ohno, Y., Tanaka-Okamoto, M., Ishizaki, H., Shirai, M., Mihara, K., Brock, W. H., Miyoshi, J., Takihara, Y.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 33 Pages: 644-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390195
[Journal Article] Scmh1 has E3 ubiquitin ligase activity for Geminin and histone H2A and regulates Geminin stability directly or indirectly via transcription repression of Hoxa9 and Hoxb42013
- Author(s)
  Yasunaga, S., Ohtsubo, M., Ohno, Y., Saeki, K., Kurogi. T., Tanaka-Okamoto, M., Ishizaki, H., Shirai, M., Mihara, K., Brock, H. W., Miyoshi, J. & Takihara Y
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 33(4) Issue: 4 Pages: 644-660
- DOI
  10.1128/mcb.00974-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23618008, KAKENHI-PROJECT-23659096, KAKENHI-PROJECT-24591595, KAKENHI-PROJECT-24790976, KAKENHI-PUBLICLY-25130708, KAKENHI-PUBLICLY-23118519, KAKENHI-PUBLICLY-23130511
[Journal Article] Hoxa9 transduction induces hematopoietic stem and progenitor cell activity through direct down-regulation of geminin protein2013
- Author(s)
  Ohno Y, Yasunaga S, Janmohamed S, Ohtsubo M, Saeki K, Kurogi T, Mihara K, Iscove NN, Takihara Y
- Journal Title
  
  PLoS One
  
  Volume: 8(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790976
[Journal Article] 幹細胞における細胞周期制御特集:がん幹細胞研究の新たな展開2012
- Author(s)
  瀧原義宏、安永晋一郎、大野芳典、大坪素秋
- Journal Title
  
  血液フロンティア(医薬ジャーナル社)
  
  Volume: 22 Pages: 33-43
- Data Source
  KAKENHI-PROJECT-22390195
[Journal Article] Decreased expression in nuclear factor-kB essential modulator due to a novel splice-site mutation causes X-linked ectodermal dysplasia with immunedeficiency.2011
- Author(s)
  Karakawa, S., Okada, S., Tsumura, M., Mizoguchi, Y., Hara, K., Ohno, N., Yasunaga, S., Ohtsubo M., et al
- Journal Title
  
  Clin. Immunol.
  
  Volume: 31 Pages: 762-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23618008
[Journal Article] Decreased expression in nuclear factor-kB essential modulator due to a novel splice-site mutation causes X-linked ectodermal dysplasia with immune- deficiency2011
- Author(s)
  Karakawa, S., Okada, S., Tsumura, M., Mizoguchi, Y., Hara, K., Ohno, N., Yasunaga, S., Ohtsubo M., Kawai, T., Nishikimori, R., Sakaguchi, T., Hata, I., Sakura, N., Takihara, Y. & Kobayashi, M.
- Journal Title
  
  Clin. Immunol.
  
  Volume: 31(5) Issue: 5 Pages: 762-772
- DOI
  10.1007/s10875-011-9560-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23618008
[Journal Article] Decreased expression in nuclear factor-kB essential modulator due to a novel splice-site mutation causes X-linked ectodermal dysplasia with immunodeficiency2011
- Author(s)
  Karakawa, S., Okada, S., Tsumura, M., Mizoguchi, Y., Ohno, N., Yasunaga, S., Ohtsubo, M., Kawai, T., Nishikomori, R., Sakaguchi, T., Takihara, Y., Kobayashi, M.
- Journal Title
  
  Journal of Clinical Immunology
  
  Volume: 31(5) Pages: 762-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21602004
[Journal Article] Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential2010
- Author(s)
  Ohno, Y., Yasunaga, S., Ohtsubo, M., Mori, S., Tsumura, M., Okada, S., Ohta, T., Ohtani, K., Kobayashi, M., Takihara, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 21529-21534
- NAID
  40019027599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21602004
[Journal Article] Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.2010
- Author(s)
  Ohno, Y., Yasunaga, S., Ohtsubo, M., Mori, S., Tsumura, M., Okada, S., Ohta, T., Ohtani, K., Kobayashi, M., Takihara, Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 21529-21534
- NAID
  40019027599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21602004
[Journal Article] HOXB4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with growth potential.2010
- Author(s)
  Ohno, Y., Yasunaga, S., Ohtsubo, M., Mori, S., Tsumura, M., Okada, S., Ohta, T., Ohtani, K., Kobayashi, M., Takihara, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 21529-21534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390195
[Journal Article] HOXB4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with growth potential.2010
- Author(s)
  Ohno, Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 21529-21534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390195
[Presentation] 慢性骨髄性白血病細胞の分化と増殖を標的とした新規白血病治療法の開発2023
- Author(s)
  大野芳典、竹立恭子、白須直人、大坪素秋、瀧原義宏、安永晋一郎
- Organizer
  第２７回バイオ治療法研究会学術集会
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Molecular responses for low dose-rate irradiation in the hematopoiesis2020
- Author(s)
  Ohno Y, Suzuki-Takedachi K, Guo Y, Kanno M, Shirasu N, Yasunaga S, Ohtsubo M, TakiharaY
- Organizer
  放射線災害・医科学研究拠点第4回国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Low dose-rate irradiation preferentially exerts mitochondrial toxicity in hematopoietic stem cells.2020
- Author(s)
  Ohno Y., Suzuki-Takedachi K., Guo Y., Kanno M., Shirasu N., Ohtsubo M., TakiharaY., Yasunaga S.
- Organizer
  第８２回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Low dose rate radiation affects mitochondrial activity in the more undifferentiated hematopoietic cells.2020
- Author(s)
  Ohno Y., Suzuki-Takedachi K., Guo Y., Kanno M., Shirasu N., Yasunaga S., Ohtsubo M., TakiharaY.
- Organizer
  日本放射線影響学会第63回大会
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Low dose-rate irradiation preferentially affects the stemness of hematopoietic cells.2019
- Author(s)
  Ohno Y., Suzuki-Takedachi K., Guo Y., Kanno M., Shirasu N., Ohtsubo M., Yasunaga S.,Takihara Y.
- Organizer
  The 62th Annual Meeting of the Japanese Radiation Research Society.
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Gemininは造血幹細胞と白血病幹細胞の幹細胞性を制御する2019
- Author(s)
  竹立恭子、大野芳典、白須直人、大坪素秋、瀧原義宏、安永晋一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Gemininは造血幹細胞と白血病幹細胞の幹細胞性を制御する2019
- Author(s)
  竹立恭子、大野芳典、郭芸、大坪素秋、瀧原義宏、安永晋一郎
- Organizer
  第６２回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Analysis of the molecular response for low dose-rate irradiation in the hematopoietic stem cells.2019
- Author(s)
  Suzuki-Takedachi K., Ohno Y., Santo M., Guo Y., Kanno M., Shirasu N., Ohtsubo M., Yasunaga S., Takihara Y.
- Organizer
  The 62th Annual Meeting of the Japanese Radiation Research Society.
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Low dose-rate irradiation preferentially affects the stemness of hematopoietic cells2019
- Author(s)
  Ohno Y, Suzuki-Takedachi K、Guo Y, Kanno M、Shirasu N、Yasunaga S、Ohtsubo M、 TakiharaY
- Organizer
  日本放射線影響学会第62回大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Low dose-rate irradiation promotes down-regulation of hematopoietic stem cell activity2019
- Author(s)
  Ohno Y, Suzuki-Takedachi K、Guo Y, Kanno M、Shirasu N、Yasunaga S、Ohtsubo M、 TakiharaY
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 低線量率放射線被ばくは造血幹細胞活性を低下させる2019
- Author(s)
  大野芳典、竹立恭子、郭芸、菅野雅元、白須直人、大坪素秋、瀧原義宏、安永晋一郎
- Organizer
  第６２回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Low dose-rate irradiation preferentially affects hematopoietic stem cell activity.2019
- Author(s)
  Ohno Y, Suzuki-Takedachi K, Guo Y, Kanno M、Shirasu N、Yasunaga S、Ohtsubo M、 TakiharaY
- Organizer
  第17回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 幹細胞活性制御の中核因子Gemininを標的とした白血病幹細胞制御法の開発2019
- Author(s)
  竹立恭子、大野芳典、白須直人、大坪素秋、瀧原義宏、安永晋一郎
- Organizer
  第23回バイオ治療法研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Analysis of the molecular response for low dose-rate irradiation in the hematopoietic stem cells2019
- Author(s)
  Suzuki-Takedachi K, Ohno Y, Guo Y, Kanno M、Shirasu N、Yasunaga S、Ohtsubo M、 TakiharaY
- Organizer
  日本放射線影響学会第62回大会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] MolecularLow-dose-rate irradiation preferentially affects hematopoietic stem cell activity.2019
- Author(s)
  Ohno Y., Suzuki-Takedachi K., Guo Y., Kanno M., Shirasu N., Yasunaga S., Ohtsubo M. , Takihara Y.
- Organizer
  The 17th Stem Cell Research Symposium
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] Low dose-rate irradiation promotes down-regulation of hematopoietic stem cell activity.2019
- Author(s)
  Ohno Y., Suzuki-Takedachi K., Guo Y., Kanno M., Shirasu N., Yasunaga S., Ohtsubo M., Takihara Y.
- Organizer
  The 81st Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19K08828
[Presentation] 低線量率放射線被ばくは造血幹細胞活性を低下させる2019
- Author(s)
  大野芳典、竹立恭子、郭芸、菅野雅元、白須直人、大坪素秋、瀧原義宏、安永晋一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 低線量率放射線による造血幹細胞の活性低下とその分子機序2019
- Author(s)
  大野　芳典
- Organizer
  基研研究会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 造血における低線量率放射線に対する分子応答2018
- Author(s)
  大野芳典, 竹立恭子, 山藤幹茂子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 低線量率放射線が造血幹細胞活性に与える影響2018
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  中国地区放射線影響研究会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 低線量率放射線が造血幹細胞活性に与える影響2018
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  中国地区放射線影響研究会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 幹細胞活性制御因子Gemininの白血病の病態制御における役割2018
- Author(s)
  大野芳典, 竹立恭子, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第22回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] Effect of low dose-rate irradiation on the hematopoietic stem cells.2018
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第80回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 造血における低線量率放射線に対する分子応答2018
- Author(s)
  大野芳典, 竹立恭子, 山藤幹茂子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Effect of low dose-rate irradiation on the hematopoietic stem cells.2018
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第80回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 低線量率放射線による造血幹細胞の機能低下とその分子機序2018
- Author(s)
  大野芳典, 竹立恭子, 山藤幹茂子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第61回日本放射線影響学会大会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 低線量率放射線による造血幹細胞の機能低下とその分子機序2018
- Author(s)
  大野芳典, 竹立恭子, 山藤幹茂子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第61回日本放射線影響学会大会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 幹細胞活性制御因子Gemininの白血病の病態制御における役割2018
- Author(s)
  大野芳典, 竹立恭子、白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第22回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Molecular response for low dose-rate irradiation in the hematopoietic system2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 低線量率放射線照射環境下における造血システムへの影響とその分子応答2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第60回日本放射線影響学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 造血幹細胞の細胞周期と分化を制御する中核因子Geminin2017
- Author(s)
  大野芳典, 竹立恭子、白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第２１回バイオ治療法研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Molecular response for low dose-rate irradiation in the hematopoietic system2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 低線量率放射線が造血に与える影響2017
- Author(s)
  大野芳典, 竹立恭子, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 造血幹細胞の細胞周期制御と分化制御における分子機能2017
- Author(s)
  竹立恭子, 大野芳典, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 膜透過型ペプチドを用いた幹細胞活性制御因子Gemininの発現制御法の開発2017
- Author(s)
  竹立恭子、大野芳典,白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第２１回バイオ治療法研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Molecular responses for low dose-rate irradiation in the hematopoietic stem cells.2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 膜透過型ペプチドを用いた幹細胞活性制御因子Gemininの発現制御法の開発2017
- Author(s)
  竹立恭子, 大野芳典, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第２１回バイオ治療法研究会学術集会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 低線量率放射線被ばくに対する造血システムの分子応答2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第5８回原爆後障害研究会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 低線量率放射線が造血に与える影響2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] 造血幹細胞の細胞周期と分化を制御する中核因子Geminin2017
- Author(s)
  大野芳典, 竹立恭子, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第２１回バイオ治療法研究会学術集会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] Molecular responses for low dose-rate irradiation in the hematopoietic stem cells.2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元, 白須直人, 安永晋一郎, 大坪素秋, 瀧原義宏
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 低線量率放射線照射環境下における造血システムへの影響とその分子応答2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第60回日本放射線影響学会学術集会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Effect of low dose-rate irradiation on the hematopoietic stem cells2017
- Author(s)
  Ohno, Y., Shirasu, N., Suzuki-Takedachi, K., Santo, M., Guo, Y., Kanno, M., Yasunaga, S., Ohtsubo, M., Takihara, Y.
- Organizer
  The 1st International Symposium of the network-type Joint Usage/ Research Center for Radiation Disaster Medical Science
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2017-02-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 造血幹細胞の細胞周期制御と分化制御における分子機能2017
- Author(s)
  竹立恭子、大野芳典,白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Effect of low dose-rate irradiation on the hematopoietic system.2017
- Author(s)
  Ohno Y. , Shirasu N., Suzuki-Takedachi K., Santo M.,Guo Y., Kanno M., Yasunaga S., Ohtsubo M. , Takihara Y.
- Organizer
  The 1st International Symposium of the network-type Joint Usage/Research Center for Radiation Disaster Medical Science
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2017-02-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] 低線量率放射線被ばくに対する造血システムの分子応答2017
- Author(s)
  大野芳典, 竹立恭子, 郭芸, 菅野雅元、白須直人, 安永晋一郎, 大坪素秋,瀧原義宏
- Organizer
  第5８回原爆後障害研究会
- Data Source
  KAKENHI-PROJECT-17K00552
[Presentation] Low dose-rate irradiation specifically affects hematopoietic stem cells2016
- Author(s)
  Takihara, Y., Ohno, Y., Suzuki-Takedachi, K., Santo M., Yasunaga, S., Ohtsubo, M., Naka, K.
- Organizer
  45th Annual Scientific Meeting of the International Society of Experimental Hematology
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] Low dose-rate irradiation specifically affects hematopoietic stem cells.2016
- Author(s)
  Ohno, Y., Suzuki-Takedachi, K., Santo, M., Guo, Y., Kanno, M., Yasunaga, S., Ohtsubo, M., Naka, K., Takihara, Y.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] A new strategy for manipulating expression and activity of Geminin could make it possible to regulate cell fates of HSCs.2016
- Author(s)
  Takihara Y., Ohno Y., Suzuki-Takedachi K., Santo M., Yasunaga S., Ohtsubo M., Naka K.
- Organizer
  ISEH (International Society for Experimental Hematology) 45th Annual Scientific Meeting
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2016-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Effect of low dose-rate irradiation on the hematopoietic system.2016
- Author(s)
  Ohno Y., Suzuki-Takedachi K., , Santo M., Guo Y., Kanno, Yasunaga S., Ohtsubo M., Naka K., Takihara Y.
- Organizer
  The 14th Stem Cell Research Symposium
- Place of Presentation
  Awaji, Japan
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] 造血幹細胞の低線量率放射線被ばくに対する分子応答の解析2016
- Author(s)
  大野芳典、鈴木-竹立恭子、山藤幹茂子、郭芸、菅野雅元、白須直人、大坪素秋、仲一仁、安永晋一郎、瀧原義宏
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 造血幹細胞の低線量率放射線被ばくに対する分子応答の解析2016
- Author(s)
  大野芳典、鈴木－竹立恭子、山藤幹茂子、郭芸、菅野雅元、白須直人、大坪素秋、仲一仁、安永晋一郎、瀧原義宏
- Organizer
  第３９回日本分子生物学年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Effect of low dose-rate irradiation on the hematopoietic system.2016
- Author(s)
  Ohno, Y., Suzuki-Takedachi, K., Santo, M., Guo, Y., Kanno, M., Yasunaga, S., Ohtsubo, M., Naka, K., Takihara, Y.
- Organizer
  The 14th Stem Cell Research Symposium
- Place of Presentation
  Awaji, Japan
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] 低線量率被ばくに対する造血幹細胞の分子応答の解析2016
- Author(s)
  大野芳典、竹立恭子、山藤幹茂子、郭芸、菅野雅元、白須直人、安永晋一郎、大坪素秋、仲一仁
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  広島
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16H02955
[Presentation] Manipulation of the Geminin activity by using cell-penetrating Geminin and its domain-specific mutants2015
- Author(s)
  Ohno　Yoshinori
- Organizer
  第13回　幹細胞シンポジウム
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26860734
[Presentation] Analysis of molecular role for Geminin in self-renewal and differentiation of HSCs.2015
- Author(s)
  Suzuki-Takedachi K.,Ohno Y., Kurogi T., Santo M., Yasunaga S., Ohtsubo M., Naka K., Takihara Y.
- Organizer
  The 77th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Kanazawa, Japan.
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] A new strategy for manipulating expression and activity of Geminin, a cell-fate determinant for HSCs2015
- Author(s)
  Ohno　Yoshinori
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860734
[Presentation] DNA複製とクロマチンリモデリングを制御するCell-penetrating (CP-) Gemininの開発2015
- Author(s)
  Takedachi Kyoko, Ohno　Yoshinori
- Organizer
  第38回　分子生物学会総会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860734
[Presentation] Manipulation of the Geminin activety by using cell-penetrating Geminin and its domein-specific mutants.2015
- Author(s)
  Ohno Y., Yasunaga S., Suzuki-Takedachi K., Kurogi T., Santo M., Ohtsubo M., Naka K., Takihara Y.
- Organizer
  The 13th Stem Cell Research Symposium
- Place of Presentation
  Tokyo, Japan.
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] A new strategy for manipulating expression and activety of Geminin, a cell-fate determinant for HSCs.2015
- Author(s)
  Ohno Y., Suzuki-Takedachi K., Kurogi T., Santo M., Yasunaga S., Ohtsubo M., Naka K., Takihara Y.
- Organizer
  The 77th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Kanazawa, Japan.
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] DNA複製とクロマチンリモデリングを制御するCell-penetrating (CP-)Gemininの開発2015
- Author(s)
  竹立（鈴木）恭子、大野芳典、黒木利知、安永晋一郎、山藤幹茂子、舛廣善和、花澤重正、大坪素秋、仲一仁、瀧原義宏
- Organizer
  第３８回日本分子生物学会・第８８回日本生化学会合同年会（BMB２０１５）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Effects of low-dose irradiation on the hematopoietic system.2015
- Author(s)
  Yasunaga S., Ohno Y., Suzuki-Takedachi K., Kurogi T., Santo M., Ohtsubo M., Takihara Y.
- Organizer
  The 5th International Symposium of RIRBM, Hiroshima University
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2015-03-02
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Expression and molecular function of Geminin, which governs hematopoietic stem cell activity2013
- Author(s)
  Takihara Y., Yasunaga S., Ohno Y., Kurogi T., Suzuki-Takedachi K., Nakashima Y., Ohtsubo M.,
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  Yokohama, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Negative feed-back loop regulates transcription of the Geminin gene, which governs HSC activity2013
- Author(s)
  Ohno Y., Yasunaga S., Kurogi T., Suzuki-Takedachi K., Nakashima Y., Ohtsubo M., Takihara Y.
- Organizer
  The 75th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Negative feed-back loop regulates transcription of the Geminin gene, which governs HSC activity2013
- Author(s)
  大野　芳典
- Organizer
  第７５回　日本血液学会
- Place of Presentation
  北海道　ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Molecular role for Geminin in switching self-renewal and differentiation of hematopoietic cells2013
- Author(s)
  Yasunaga S., Ohno Y., Kurogi T., Suzuki-Takedachi K., Nakashima Y., Ohtsubo M., Takihara Y.
- Organizer
  The 75th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] E2F-mediated transcriptional activation of the Geminin gene is under the regulation of a negative-feedback loop2013
- Author(s)
  Ohno Y., Saeki K., Yasunaga S., Shirai M., , Kurogi T., Nakashima Y., Ohtsubo M., Takihara Y.
- Organizer
  The 11th Stem Cell Research Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Negative feed-back loop regulates E2F-mediated transcriptional activation of the Geminin gene2013
- Author(s)
  Kurogi T., Ohno Y., Yasunaga S., Suzuki-Takedachi K., Shirai M., Ohtsubo M., Takihara Y.
- Organizer
  The 36th Annual Meeting of the Molecular Biology of Japan
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Visualization and functional analysis of Geminin, a candidate molecule governing self-renewal and cellular differentiation of hematopoietic stem cells2013
- Author(s)
  Yasunaga S., Ohno Y., Kurogi T., Saeki K., Nakashima Y., Ohtsubo M., Takihara Y.
- Organizer
  The 11th Stem Cell Research Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] E2F-mediated transcriptional activation of the Geminin gene is under the regulation of a negative-feedback loop2013
- Author(s)
  大野　芳典
- Organizer
  第１１回　幹細胞シンポジウム
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Negative feed-back loop regulates E2F-mediated transcriptional activation of the Geminin gane2013
- Author(s)
  Toshiaki Kurogi, Yoshinori Ohno, Shin'ichiro Yasunaga, Kyoko Suzuki-Takedachi, Manabu Shirai, Motoaki Ohtsubo, Yoshihiro Takihara
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Negative feed-back loop regulates transcription of the Geminin gene, which governs HSC activity2013
- Author(s)
  Yoshinori Ohno, Shin'ichiro Yasunaga , Toshiaki Kurogi, Kyoko Suzuki-Takedachi, Yoshie Nakashima, Motoaki Ohtsubo, Yoshihiro Takihara
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Molecular analysis of a role for Geminin in regulating proliferation and differentiation of hematopoietic stem/progenitor cells by visualizing Geminin expression2013
- Author(s)
  Suzuki-Takedachi K., Yasunaga S., Ohno Y., Kurogi T., Ohtsubo M., Takihara Y.
- Organizer
  The 36th Annual Meeting of the Molecular Biology of Japan
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Scmh1 is required for maintaining hematopoietic homeostasis through the molecular network governing Geminin expression.2012
- Author(s)
  Ohno, Y.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390195
[Presentation] A new approach for activating mouse hematopoietic stem and progenitor cells by manipulating Geminin expression2012
- Author(s)
  Yasunaga S., Ohno Y., Ohtsubo M., Saeki K., Nakashima Y., Takihara Y.
- Organizer
  The 10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Repression of Geminin plays an important role in Hoxa9-induced hematopoiesis and leukemogenesis.2012
- Author(s)
  Ohno, Y.
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22390195
[Presentation] Scmh1 is required for maintaining hematopoietic homeostasis through the molecular network governing Geminin expression2012
- Author(s)
  Ohno, Y.
- Organizer
  The 35th Annual Meeting of the Molecular Biology of Japan
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Repression of Geminin plays an important role in Hoxa9-induced hematopoiesis and leukemogenesis2012
- Author(s)
  Ohno, Y.
- Organizer
  The 74th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Hole for an Scmh1-mediated molecular network governing Geminin expression in hematopoiesis2012
- Author(s)
  Ohtsubo, M., Yasunaga, Y., Ohno, Y., Kawashima, A., Tetsuguchi, H., Saeki, K, Nakashima, Y., Takihara, Y.
- Organizer
  International Symposium 50^<th> Anniversary of RIRBM, Hiroshima University
- Place of Presentation
  広島国際会議場
- Year and Date
  2012-02-21
- Data Source
  KAKENHI-PROJECT-21602004
[Presentation] Scmh1 composes a molecular network regulating Geminin protein to govern hematopoiesis2012
- Author(s)
  Ohno, Y.
- Organizer
  The 10th Stem Cell Research Symposium
- Place of Presentation
  Awaji, Japan
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Scmh1 regulates Geminin through the ubiquitin- proteasome systems to govern hematopoietic homeostasis2012
- Author(s)
  Yasunaga S., Ohno Y., Saeki K., Nakashima Y., Ohtsubo M., Takihara Y.
- Organizer
  The 74th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Scmh1 is required for maintaining hematopoietic homeostasis through the molecular network governing Geminin expression2012
- Author(s)
  Yoshinori Ohno, Shin'ichiro Yasunaga, Keita Saeki, Motoaki Ohtsubo, Toshiaki kurogi, Yoshie Nakashima, Yoshihiro Takihara
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Role for an Scmh1-mediated molecular network governing Geminin expression in hematopoiesis2012
- Author(s)
  Ohtsubo, M., Yasunaga, Y., Ohno, Y., Kawashima, A., Tetsuguchi, H., Saeki, K., Nakashima, Y., Takihara, Y.
- Organizer
  International Symposium 50^<th> Anniversary of RIRBM, Hiroshima University
- Place of Presentation
  広島国際会議場
- Year and Date
  2012-02-21
- Data Source
  KAKENHI-PROJECT-21602004
[Presentation] Repression of Geminin plays an important role in Hoxa9-induced hematopoiesis and leukemogenesis2012
- Author(s)
  Yoshinori Ohno, Shin'ichiro Yasunaga, Motoaki Ohtsubo, Keita Saeki, Yoshie Nakashima, Yoshihiro Takihara
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  国立京都国際会議場
- Data Source
  KAKENHI-PROJECT-24790976
[Presentation] Scmh1 is required for maintaining hematopoietic homeostasis through the molecular network governing Geminin expression2012
- Author(s)
  Ohno Y.
- Organizer
  The 35th Annual Meeting of the Molecular Biology of Japan
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Novel molecular regulatory network governing Geminin maintains hematopoietic homeostasis.2012
- Author(s)
  Takihara, Y., Yasunaga, S., Ohno, Y., Saeki, K., Nakashima, Y., Ohtsubo, M.
- Organizer
  41st annual scientific meeting of the international society for hematology and stem cells
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-22390195
[Presentation] A new strategy for maintaining HSC activity through the modulation of Geminin expression2011
- Author(s)
  Yasunaga, Y., Ohno, Y., Ohtsubo, M., Furutani, T., Kawashima, A., Tetsuguchi, H., Saeki, K., Nakashima, Y., Takihara, Y.
- Organizer
  日本血液学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21602004
[Presentation] Study of a 5-FU-induced stabilization signal for Scmh1, a component of Polycomb-group complex 1 E3 ligase2009
- Author(s)
  Ohtsubo, M., Yasunaga, S., Ohno, Y., Tsumura, M., Kageyama, Y., Mori, S., Takihara, Y.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21602004
[Presentation] Role of Scmh1 in the regulation of Polycomb-group complex 1, which acts as the E3 ubiquitin ligase for histone H2A and Geminin2009
- Author(s)
  Ohtsubo, M., Yasunaga, S., Tsumura, M., Ohno, Y., Kageyama, Y., Kimura, S., Tokimoto, R., Takihara, Y.
- Organizer
  The 7th Stem Cell Research Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2009-05-16
- Data Source
  KAKENHI-PROJECT-21602004
[Presentation] Analysis of molecular rele for Geminin in self-renewal and differentiation of HSCs.
- Author(s)
  Suzuki-Takedachi K., Yasunaga S., Ohno Y., Kurogi T., Santo M., Ohtsubo M., Takihara Y.
- Organizer
  The 5th International Symposium of RIRBM, Hiroshima University
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2015-03-02 – 2015-03-03
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Geminin visualization aids detailed molecular analysis of self-renewing hematopoietic stem cells.
- Author(s)
  Yasunaga S., Ohno Y., Suzuki-Takedachi K., Kurogi T., Santo M., Ohtsubo M., Takihara Y.
- Organizer
  The 76th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Osaka, Japan
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] A new strategy for manipulating HSC activity through the modulation of Geminin expression.
- Author(s)
  Yasunaga S., Ohno Y., Ohtsubo M., Furutani T., Kawashima A., Tetsuguchi H., Saeki K., Nakashima Y., Takihara Y.
- Organizer
  第７３回日本血液学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23618008
[Presentation] Geminin-EYFP knock-in mice provide a powerful tool for dissecting a molecular mechanism regulating self-renewal or differentiation of hematopoietic stem cells.
- Author(s)
  Suzuki-Takedachi K., Yasunaga S., Ohno Y., Kurogi T., Ohtsubo M., Takihara Y.
- Organizer
  The 37th Annual Meeting of the Molecular Biology of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Geminin regulates transcription via chromatin remodeling to govern cellular proliferation and differentiation.
- Author(s)
  Ohno Y., Yasunaga S., Kurogi T., Suzuki-Takedachi K., Santo M., Ohtsubo M., Takihara Y.
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Direct transmission of a cell-penetrating form of Geminin, a regulator for hematopoietic stem cells.
- Author(s)
  Ohno Y., Yasunaga S., Kurogi T., Suzuki-Takedachi K., Santo M., Ohtsubo M., Takihara Y.
- Organizer
  The 76th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Osaka, Japan
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Direct transmission of a cell-penetrating form of Geminin, a regulator for hematopoietic stem cells
- Author(s)
  大野　芳典
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪　大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26860734
[Presentation] Cell-penetrating recombinant Geminin protein may provide a new strategy for regulating self-renewal or cellular differentiation in hematopoietic stem cells.
- Author(s)
  Kurogi T., Ohno Y., Yasunaga S., Suzuki-Takedachi K., Santo M., Masuhiro Y., Hanazawa S., Ohtsubo M., Takihara Y.
- Organizer
  The 37th Annual Meeting of the Molecular Biology of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Direct transduction of a cell-penetrating form of Geminin, a molecule regulating DNA replication and chromatin remodeling.
- Author(s)
  Takihara Y., Yasunaga S., Ohno Y., Kurogi T., Suzuki-Takedachi K., , Santo M., Ohtsubo M.
- Organizer
  ISEH (International Society for Experimental Hematology) 43rd Annual Scientific Meeting
- Place of Presentation
  Montreal , Canada
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Cell-penetrating Geminin is exerted to provide a new strategy for manipulating the activity and number of HSCs.
- Author(s)
  Kurogi T., Ohno Y., Yasunaga S., Suzuki-Takedachi K., Santo M., Ohtsubo M., Takihara Y.
- Organizer
  The 5th International Symposium of RIRBM, Hiroshima University
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2015-03-02 – 2015-03-03
- Data Source
  KAKENHI-PROJECT-26501004
[Presentation] Identification and functional analysis of self-renewing hematopoietic stem cells by using Geminin-EYFP knock-in mice.
- Author(s)
  Yasunaga S., Ohno Y., Suzuki-Takedachi K., Kurogi T., , Santo M., Ohtsubo M., Takihara Y.
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-26501004

1. YASUNAGA Shin ichiro (50336111)

# of Collaborated Projects: 9 results

# of Collaborated Products: 101 results
2. TAKIHARA Yoshihiro (60226967)

# of Collaborated Projects: 7 results

# of Collaborated Products: 67 results
3. OHTSUBO Motoaki (10211799)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
4. SHIRAI Manabu (70294121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TSUJI Kohichiro (50179991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 白須直人 (70551422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. TAKEDACHI Kyoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
8. Sato MIMOKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KUROGI Toshiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
10. YAMADA Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAJIMA Go

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. OKADA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. TSUMURA Miyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. HARA Keiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 森尾友宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 瀬川波子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohno Yoshinori 大野 芳典

OHNO Yoshinori 大野 芳典

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Development of protection method against low dose rate radiation exposure of hematopoietic systemPrincipal Investigator

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Analysis for molecular role of Geminin in hematopoietic and leukemia stem cellPrincipal Investigator

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Analysis of the molecular function of Geminin in leukemogenesisPrincipal Investigator

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[Book] 血液フロンティア・がん幹細胞研究の新たな展開・幹細胞における細胞周期制御2012

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[Book] 血液フロンティア・がん幹細胞研究の新たな展開・幹細胞における細胞周期制御2012

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[Journal Article] 造血幹細胞活性に対する低線量被ばくの影響．2020

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[Journal Article] 低線量率放射線被ばくの造血システムに対する放射線障害の解析2018

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Ohno Yoshinori 大野芳典

OHNO Yoshinori 大野芳典

[Journal Article] 骨髄の組織反応 (特集放射線生物学と放射線防護を繋ぐ組織反応研究)2017

[Journal Article] 幹細胞における細胞周期制御特集:がん幹細胞研究の新たな展開2012