Sohma Youhei 相馬洋平

… Alternative Names

SOHMA Youhei 相馬洋平

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Researcher Number	10565518
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 和歌山県立医科大学, 薬学部, 教授 2017 – 2020: 東京大学, 大学院薬学系研究科(薬学部), グループリーダー(講師相当) 2016: 東京大学, 大学院薬学系研究科(薬学部), 特任研究員 2012: 東京大学, 薬学研究科(研究院), 研究員 2011: 東京大学, 大学院・薬学系研究科, 特任研究員 2010: 京都薬科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Drug development chemistry / Transformative Research Areas, Section (II) / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Medium-sized Section 47:Pharmaceutical sciences and related fields Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator アミロイド / 凝集 / 神経変性疾患 / 触媒 / タンパク質 / 阻害剤 / ペプチド / アルツハイマー病 / TDP-43 / タンパク … More / 立体構造 / 酸素化 / 阻害 / α-シヌクレイン / タウ / 光酸素化触媒 / 創薬 / 結晶 / 蛋白質 / 有機化学 / 薬学 / 創薬化学 / クリックペプチド / イソペプチド … More Except Principal Investigator β-セクレターゼ / 酵素阻害剤 / クリックペプチド / クリプタイド / ss-セクレターゼ / 基質遷移状態 / ドラッグデザイン / プロテアーゼ阻害剤 / 分子認識 / プロテアーゼ Less

アミロイドを解明・治療・利用する化学研究Principal Investigator
- Principal Investigator
  
  相馬洋平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Wakayama Medical University
TDP-43アミロイドに対する特異的リガンドの創製プラットフォームの構築Principal Investigator
- Principal Investigator
  
  相馬洋平
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Wakayama Medical University
Development of innovative aggregation inhibition strategies for amyloid proteins that cause neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  Sohma Youhei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Wakayama Medical University
Control of intracellular amyloid dynamics using photooxygenation catalystsPrincipal Investigator
- Principal Investigator
  
  Sohma Youhei
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Development of aggregation inhibition strategy for pathogenic amyloid proteinsPrincipal Investigator
- Principal Investigator
  
  Sohma Youhei
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
Research on pathological mechanism of amyloid beta peptide and application to the aggregation inhibitorPrincipal Investigator
- Principal Investigator
  
  YOUHEI Sohma
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
  Kyoto Pharmaceutical University
Design and Medicinal Chemistry Research on Therapeutics ofDifficult Diseases based on Molecular Recognition
- Principal Investigator
  
  KISO Yoshiaki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagahama Institute of Bio-Science and Technology
  Kyoto Pharmaceutical University

[Book] 遺伝子医学MOOK21号最新ペプチド合成技術とその創薬研究への応用(木曽良明編集)O-アシルイソペプチドの合成.2012
- Author(s)
  相馬洋平・木曽良明
- Publisher
  メディカル・ドゥ
- Data Source
  KAKENHI-PROJECT-21249007
[Book] ペプチド医薬の最前線2012
- Author(s)
  相馬洋平
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22790118
[Book] 最新ペプチド合成技術とその創薬研究への応用2011
- Author(s)
  相馬洋平
- Publisher
  遺伝子医学MOOK21号, メディカルドウ
- Data Source
  KAKENHI-PROJECT-22790118
[Book] Wiley Encyclopedia of Chemical Biology, Volume 1 (Tadhg P. Begley, Chief Advisor)2009
- Author(s)
  Yoshiaki Kiso, Atsuhiko Taniguchi, Youhei Sohma
- Publisher
  Click Peptides: Design and Applica- tions.
- Data Source
  KAKENHI-PROJECT-21249007
[Journal Article] Rose Bengal Promoted Catalytic Amyloid-β Oxygenation by Sonoactivation2023
- Author(s)
  Sohma Youhei、Hori Yukiko、Tomita Taisuke、Kanai Motomu、Atsumi Wataru、Kawabata Keiichi、Yamane Mina、Oi Miku、Mitsunuma Harunobu
- Journal Title
  
  Synlett
  
  Volume: 35 Issue: 08 Pages: 920-924
- DOI
  10.1055/a-2182-7614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06045, KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-23K21357
[Journal Article] Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins2023
- Author(s)
  Umeda Hiroki、Sawazaki Taka、Furuta Masahiro、Suzuki Takanobu、Kawashima Shigehiro A.、Mitsunuma Harunobu、Hori Yukiko、Tomita Taisuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 14 Issue: 15 Pages: 2710-2716
- DOI
  10.1021/acschemneuro.3c00264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KK0133, KAKENHI-PROJECT-21K15220, KAKENHI-PLANNED-20H05843, KAKENHI-PROJECT-23H00394, KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-23K21357
[Journal Article] Photo‐oxygenation of histidine residue inhibits α‐synuclein aggregation2023
- Author(s)
  Nakamura Reito、Tomizawa Ikumi、Iwai Atsushi、Ikeda Tetsuo、Hirayama Kota、Chiu Yung Wen、Suzuki Takanobu、Tarutani Airi、Mano Tatsuo、Iwata Atsushi、Toda Tatsushi、Sohma Youhei、Kanai Motomu、Hori Yukiko、Tomita Taisuke
- Journal Title
  
  The FASEB Journal
  
  Volume: 37 Issue: 12
- DOI
  10.1096/fj.202301533r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KK0133, KAKENHI-PROJECT-22K07512, KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-23H00394, KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-23K21357
[Journal Article] Attenuation of α-synuclein aggregation by catalytic photo-oxygenation2023
- Author(s)
  Iwai Atsushi、Nakamura Reito、Tomizawa Ikumi、Mitsunuma Harunobu、Hori Yukiko、Tomita Taisuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  Chemical Communications
  
  Volume: 59 Issue: 38 Pages: 5745-5748
- DOI
  10.1039/d3cc00665d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KK0133, KAKENHI-PROJECT-23H00394, KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-23K21357
[Journal Article] Modular synthetic strategy for N/C‐terminal protected amyloidogenic peptides2023
- Author(s)
  Sawazaki Taka, Sohma Youhei
- Journal Title
  
  Journal of Peptide Science
  
  Volume: 30 Issue: 3
- DOI
  10.1002/psc.3546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14325, KAKENHI-PROJECT-21H02602
[Journal Article] Activatable iodinated BODIPYs for selective imaging and photodynamic disruption of amyloid structures in pathogenic bacterial biofilms2022
- Author(s)
  Torra Joaquim、Sawazaki Taka、Bondia Patricia、Nonell Santi、Kanai Motomu、Sohma Youhei、Flors Cristina
- Journal Title
  
  Sensors and Actuators B: Chemical
  
  Volume: 371 Pages: 132475-132475
- DOI
  10.1016/j.snb.2022.132475
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20727, KAKENHI-PROJECT-20H00489, KAKENHI-PROJECT-21H02602
[Journal Article] Photo-Oxygenation as a New Therapeutic Strategy for Neurodegenerative Proteinopathies by Enhancing the Clearance of Amyloid Proteins2022
- Author(s)
  Tomizawa Ikumi、Nakagawa Hanako、Sohma Youhei、Kanai Motomu、Hori Yukiko、Tomita Taisuke
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 14
- DOI
  10.3389/fnagi.2022.945017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-23K21357, KAKENHI-PROJECT-21H02602
[Journal Article] Promotion in the Clearance of Aggregated Aβ In Vivo Using Amyloid Selective Photo-Oxygenation Technology2022
- Author(s)
  Hori Yukiko、Sohma Youhei、Kanai Motomu、Tomita Taisuke
- Journal Title
  
  Neuroscience Insights
  
  Volume: 17 Pages: 0000-0000
- DOI
  10.1177/26331055221126179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-23K21357, KAKENHI-PROJECT-20H00489, KAKENHI-PROJECT-21H02602
[Journal Article] Knoevenagel Condensation between 2-Methyl-thiazolo[4,5-<i>b</i>]pyrazines and Aldehydes2022
- Author(s)
  Taka Sawazaki, Youhei Sohma, Motomu Kanai
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 70 Issue: 1 Pages: 82-84
- DOI
  10.1248/cpb.c21-00780
- NAID
  130008138742
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2022-01-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-21K20727, KAKENHI-PROJECT-20H00489
[Journal Article] Therapeutic strategy for neurodegenerative diseases by photooxygenation reaction using chemical catalysts2022
- Author(s)
  相馬洋平、金井求
- Journal Title
  
  生化学
  
  Volume: 94 Issue: 3 Pages: 406-410
- DOI
  10.14952/SEIKAGAKU.2022.940406
- ISSN
  0037-1017
- Year and Date
  2022-06-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-21H02602
[Journal Article] Catalytic photooxygenation degrades brain Aβ in vivo2021
- Author(s)
  Nagashima Nozomu、Ozawa Shuta、Furuta Masahiro、Oi Miku、Hori Yukiko、Tomita Taisuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 13 Pages: 0-1
- DOI
  10.1126/sciadv.abc9750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-19J14873, KAKENHI-PROJECT-20J22142, KAKENHI-PROJECT-18K06653, KAKENHI-PROJECT-19K22484, KAKENHI-PROJECT-20H00489
[Journal Article] Chemical catalyst-promoted photooxygenation of amyloid proteins2021
- Author(s)
  Youhei Sohma, Taka Sawazaki, Motomu Kanai
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 19 Issue: 46 Pages: 10017-10029
- DOI
  10.1039/d1ob01677f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-21K20727, KAKENHI-PROJECT-20H00489
[Journal Article] Nanoscale view of amyloid photodynamic damage2020
- Author(s)
  P. Bondia, J. Torra, C. M. Tone, T. Sawazaki, A. Valle, B. Sot, S. Nonell, M. Kanai, Y. Sohma, C. Flors
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 142 Issue: 2 Pages: 922-930
- DOI
  10.1021/jacs.9b10632
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22484, KAKENHI-PROJECT-17H01522, KAKENHI-PROJECT-16H06216, KAKENHI-PROJECT-20J15211
[Journal Article] Design, synthesis, and properties of a chemically-tethered amyloid-β segment trimer resistant to inter-trimer mis-aggregation2020
- Author(s)
  K. Shinoda, M. Kanai, Y. Sohma
- Journal Title
  
  J. Org. Chem.
  
  Volume: 85 Issue: 3 Pages: 1635-1643
- DOI
  10.1021/acs.joc.9b02612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22484, KAKENHI-PROJECT-16H06216
[Journal Article] Palladium-Catalyzed C–H Heteroarylation of 2,5-Disubstituted Imidazoles2019
- Author(s)
  Takaya Togo, Youhei Sohma, Yoichiro Kuninobu, Motomu Kanai
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 3 Pages: 196-198
- DOI
  10.1248/cpb.c18-00586
- NAID
  130007607157
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06216
[Journal Article] Photo-oxygenation inhibits tau amyloid formation2019
- Author(s)
  Suzuki T*, Hori Y*, Sawazaki T, Shimizu Y, Nemoto Y, Taniguchi A, Ozawa S, Sohma Y, Kanai M, Tomita T
- Journal Title
  
  Chem. Commun.
  
  Volume: 55(44) Issue: 44 Pages: 6165-6168
- DOI
  10.1039/c9cc01728c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06653, KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K22484, KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-19J14873, KAKENHI-PROJECT-19J23179, KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-17H01522, KAKENHI-PROJECT-16H06216
[Journal Article] Design and properties of [Met35 (O)] Aβ42-lactam (Asp23/Lys28) possessing a lactam tether as a salt-bridge surrogate2019
- Author(s)
  Masashi Yamamoto, Kiyomichi Shinoda, Daisuke Sasaki, Motomu Kanai, Youhei Sohma
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 27 Issue: 5 Pages: 888-893
- DOI
  10.1016/j.bmc.2019.01.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01522, KAKENHI-PROJECT-16H06216
[Journal Article] 神経変性疾患治療を目指したアミロイドの光酸素化反応2019
- Author(s)
  堀由起子、相馬洋平
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 532-536
- NAID
  130007657600
- Data Source
  KAKENHI-PROJECT-19K22484
[Journal Article] Photophysical properties and application in live cell imaging of B,B-fluoro-perfluoroalkyl BODIPYs2019
- Author(s)
  Taniguchi Atsuhiko、Sawazaki Taka、Shimizu Yusuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  MedChemComm
  
  Volume: 印刷中 Issue: 7 Pages: 1121-1125
- DOI
  10.1039/c9md00011a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13260, KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-16H06216, KAKENHI-PROJECT-17H01522
[Journal Article] Convergent and Functional-Group-Tolerant Synthesis of B-Organo BODIPYs2018
- Author(s)
  Sawazaki Taka、Shimizu Yusuke、Oisaki Kounosuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  Organic Letters
  
  Volume: 20 Issue: 24 Pages: 7767-7770
- DOI
  10.1021/acs.orglett.8b03138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06545, KAKENHI-PLANNED-17H06442, KAKENHI-PROJECT-17H01522, KAKENHI-PUBLICLY-18H04239, KAKENHI-PROJECT-16H06216
[Journal Article] Chemically-engineered, stable oligomer mimic of amyloid beta42 containing an oxime switch for fibril formation2018
- Author(s)
  Masashi Yamamoto, Kiyomichi Shinoda, Jizhi Ni, Daisuke Sasaki, Motomu Kanai, Youhei Sohma
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 16 Issue: 35 Pages: 6537-6542
- DOI
  10.1039/c8ob01875h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06216
[Journal Article] Hydroxy Group Directed Catalytic Hydrosilylation of Amides2018
- Author(s)
  Ni Jizhi、Oguro Tsubasa、Sawazaki Taka、Sohma Youhei、Kanai Motomu
- Journal Title
  
  Organic Letters
  
  Volume: 20 Issue: 23 Pages: 7371-7374
- DOI
  10.1021/acs.orglett.8b03014
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06442, KAKENHI-PROJECT-17H01522, KAKENHI-PROJECT-16H06216
[Journal Article] Near-Infrared Photoactivatable Oxygenation Catalysts of Amyloid Peptide2018
- Author(s)
  Ni Jizhi、Taniguchi Atsuhiko、Ozawa Shuta、Hori Yukiko、Kuninobu Yoichiro、Saito Takashi、Saido Takaomi C.、Tomita Taisuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  Chem
  
  Volume: 4 Issue: 4 Pages: 807-820
- DOI
  10.1016/j.chempr.2018.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-17K19480, KAKENHI-PROJECT-17K13260, KAKENHI-PLANNED-17H06442, KAKENHI-PROJECT-15H02492, KAKENHI-PROJECT-16H06216, KAKENHI-PROJECT-17H01522
[Journal Article] Scandium(III) triflate-promoted serine/threonine-selective peptide bond cleavage.2017
- Author(s)
  Jizhi Ni, Youhei Sohma, Motomu Kanai
- Journal Title
  
  Chemical Communication
  
  Volume: 53 Issue: 23 Pages: 3311-3314
- DOI
  10.1039/c6cc10300f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06216
[Journal Article] ペプチド由来ファーマコフォアを有する新規アミロイドβ凝集阻害低分子化合物の創成2017
- Author(s)
  相馬洋平、新井唯正、新谷卓士、城野柳人、金井求
- Journal Title
  
  MedChemNews
  
  Volume: 27 Pages: 87-91
- NAID
  130007685109
- Data Source
  KAKENHI-PROJECT-16H06216
[Journal Article] Switchable photooxygenation catalysts that sense higher-order amyloid structures.2016
- Author(s)
  Atsuhiko Taniguchi, Yusuke Shimizu, Kounosuke Oisaki, Youhei Sohma, Motomu Kanai
- Journal Title
  
  Nature Chemistry
  
  Volume: 8 Issue: 10 Pages: 974-982
- DOI
  10.1038/nchem.2550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06216, KAKENHI-PROJECT-25460008, KAKENHI-PUBLICLY-16H01007
[Journal Article] Transition metal-free tryptophan-selective bioconjugation of proteins.2016
- Author(s)
  Yohei Seki, Takashi Ishiyama, Daisuke Sasaki, Junpei Abe, Youhei Sohma, Kounosuke Oisaki, Motomu Kanai
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 138 Issue: 34 Pages: 10798-10801
- DOI
  10.1021/jacs.6b06692
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216, KAKENHI-PROJECT-15J11454, KAKENHI-PROJECT-25460008, KAKENHI-PUBLICLY-16H01007
[Journal Article] Comparative Properties of AB1-42, AB11-42 and [Pyr11]AB11-42 Generated from O-Acyl Isopeptides2013
- Author(s)
  Youhei Sohma
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 23 Pages: 1326-1329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790118
[Journal Article] Synthesis of O-Acyl Isopeptides.2013
- Author(s)
  Youhei Sohma
- Journal Title
  
  Chemical Record
  
  Volume: 13 Issue: 2 Pages: 218-223
- DOI
  10.1002/tcr.201200023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-22790118
[Journal Article] Comparative properties of A〓1〓42, A〓11〓42, and [Pyr11]A〓11〓42 generated from O-acyl isopeptides2013
- Author(s)
  Youhei Sohma, Moe Yamasaki, Hiroyuki Kawashima, Atsuhiko Taniguchi, Masayuki Yamashita, Kenichi Akaji, Hidehito Mukai, Yoshiaki Kiso
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Pages: 1326-1329
- URL
  http://dx.doi.org/10.1016/j.bmcl.2012.12.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790118
[Journal Article] Comparative properties of Aβ1-42, Aβ11-42, and [Pyr^<11>]Aβ11-42 generated from O-acyl isopeptides2013
- Author(s)
  相馬洋平
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 23巻 Issue: 5 Pages: 1326-1329
- DOI
  10.1016/j.bmcl.2012.12.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08493, KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-25350971
[Journal Article] Through the looking glass-a new world of proteins enabled by chemical synthesis2012
- Author(s)
  Stephen Kent, Youhei Sohma, Suhuai Liu, Duhee Bang, Brad Pentelute and Kalyaneswar Mandal
- Journal Title
  
  J. Peptide Science
  
  Volume: 18 Issue: 7 Pages: 428-436
- DOI
  10.1002/psc.2421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790118
[Journal Article] Synthesis of the sphingolipid activator protein, saposin C, using an azido-protected O-acyl isopeptide as an aggregation-disrupting element2011
- Author(s)
  Hironobu Hojo, Hidekazu Katayama, Chiharu Tano, Yuko Nakahara, Azusa Yoneshige, Junko Matsuda, Youhei Sohma, Yoshiaki Kiso, Yoshiaki Nakahara
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 52 Issue: 5 Pages: 635
- DOI
  10.1016/j.tetlet.2010.11.154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790118
[Journal Article] "Click Peptide" Concept: O-Acyl Isopeptide of Islet Amyloid Poly- peptide As a non-aggregative precursor molecule.2011
- Author(s)
  Taku Yoshiya, Ayano Higa, Naoko Abe, Fukue Fukao, Tomomi Kuruma, Youhei Sohma, Yoshiaki Kiso
- Journal Title
  
  ChemBioChem.
  
  Volume: 12(8) Issue: 8 Pages: 1216-1222
- DOI
  10.1002/cbic.201100025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-22790118
[Journal Article] 'Click peptide'using production of monomer Ab from the O-acyl isopeptide : Application to assay system of aggregation inhibitors and cellular cytotoxicity2011
- Author(s)
  Youhei Sohma
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 19 Pages: 1729-1733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790118
[Journal Article] The E22SS-type mutant of amyloid SS peptide (ASS) adopts distinct selfassembly mechanisms from wild- type ASS.2011
- Author(s)
  Youhei Sohma, Hui Wang, Atsuhiko Taniguchi, Yuta Hirayama, Taeko Kakizawa, Hidehito Mukai, Yoshiaki Kiso
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 19 Issue: 12 Pages: 3787-3792
- DOI
  10.1016/j.bmc.2011.04.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-21603014, KAKENHI-PROJECT-22790118, KAKENHI-PROJECT-22790119
[Journal Article] Click peptide' using production of monomer Aβ from the O-acyl isopeptide : Application to assay system of aggregation inhibitors and cellular cytotoxicity.2011
- Author(s)
  Youhei Sohma
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 19 Pages: 1729-1733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007
[Journal Article] 'Click peptide' using production of monomer Ab from the O-acyl isopeptide: Application to assay system of aggregation inhibitors and cellular cytotoxicity.2011
- Author(s)
  Youhei Sohma, Yuta Hirayama, AtsuhikoTaniguchi, Hidehito Mukai, Yoshiaki Kiso
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 19 Issue: 5 Pages: 1729-1733
- DOI
  10.1016/j.bmc.2011.01.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-21603014, KAKENHI-PROJECT-22790118
[Journal Article] S-Acyl isopeptide method: use of allyl-type protective group for improved preparation of thioester-containing S-acyl isopeptides by Fmoc-based SPPS.2011
- Author(s)
  Taku Yoshiya, Yuka Hasegawa, Wakana Kawamura, Hiroyuki Kawashima, Youhei Sohma, Tooru Kimura, Yoshiaki Kiso
- Journal Title
  
  Biopolymers
  
  Volume: 96 Issue: 2 Pages: 228-239
- DOI
  10.1002/bip.21410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790118
[Journal Article] Synthesis of an O-acyl isopeptide by using native chemical ligation to efficiently construct a hydrophobic polypeptide.2011
- Author(s)
  Youhei Sohma, Hitomi Kitamura, Hiroyuki Kawashima, Hironobu Hojo, Masayuki Yamashita, Kenichi Akaji, Yoshiaki Kiso
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 52(52) Issue: 52 Pages: 7146-7148
- DOI
  10.1016/j.tetlet.2011.10.116
- NAID
  10030204148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-22790118, KAKENHI-PROJECT-23380065
[Journal Article] Structure-guided design and synthesis of P1' position 1-phenylcycloalkyl-amine-derived pentapeptidic BACE1 inhibitors.2011
- Author(s)
  Harichandra D. Tagad, Yoshio Hamada, Jeffrey-Tri Nguyen, Koushi Hidaka, Takashi Hamada, Youhei Sohma, Tooru Kimura, Yoshiaki Kiso
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 19 Issue: 17 Pages: 5238-5246
- DOI
  10.1016/j.bmc.2011.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-22790118, KAKENHI-PROJECT-23590137
[Journal Article] Racemization- free synthesis of cyclic peptide by use of the O-acyl isopeptide method.2010
- Author(s)
  Taku Yoshiya, Hiroyuki Kawashima, Yuka Hasegawa, Kazuhiro Okamoto, Tooru Kimura, Youhei Sohma, Yoshiaki Kiso
- Journal Title
  
  J. Peptide Science.
  
  Volume: 16(8) Issue: 8 Pages: 437-442
- DOI
  10.1002/psc.1261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007, KAKENHI-PROJECT-22790118
[Journal Article] Design of pentapeptidic BACE1 inhibitors with carboxylic acid bioisosteres at P1' and P4 positions.2010
- Author(s)
  Harichandra D. Tagad, Yoshio Hamada, Jeffrey-Tri Nguyen, Takashi Hamada, Hamdy Abdel-Rahman, Abdellah Yamani, Ayaka Nagamine, Hayato Ikari, Naoto Igawa, Koushi Hidaka, Youhei Sohma, Tooru Kimura, Yo shiaki Kiso
- Journal Title
  
  Bioorg.Med. Chem.
  
  Volume: 18(9) Issue: 9 Pages: 3175-3186
- DOI
  10.1016/j.bmc.2010.03.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007
[Journal Article] efficient synthesis of isopeptide segment and application to racemization-free segment condensation.2009
- Author(s)
  Taku Yoshiya, Hiroyuki Kawashima, YouheiSohma, Tooru Kimura, Yoshiaki Kiso: O-Acylisopeptide method
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 7(14) Issue: 14 Pages: 2894-2904
- DOI
  10.1039/b903624e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249007
[Patent] トランスサイレチンアミロイド光酸素化分解触媒2024
- Inventor(s)
  金井求、山中邦俊、山根三奈、相馬洋平、他
- Industrial Property Rights Holder
  金井求、山中邦俊、山根三奈、相馬洋平、他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-053018
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21H02602
[Patent] トリアリールメタン骨格を有する光酸素化触媒、及びこれを含有する医薬組成物2023
- Inventor(s)
  金井求、三ツ沼治信、古田将大、富田泰輔、堀由起子、相馬洋平
- Industrial Property Rights Holder
  金井求、三ツ沼治信、古田将大、富田泰輔、堀由起子、相馬洋平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-032303
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21H02602
[Patent] アミロイド触媒を用いるアミノ基の修飾方法2023
- Inventor(s)
  相馬洋平、澤崎鷹
- Industrial Property Rights Holder
  相馬洋平、澤崎鷹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-024577
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21H02602
[Patent] タウアミロイドを酸素化する光触媒2021
- Inventor(s)
  金井求、相馬洋平、富田泰輔、堀由起子、澤崎鷹、鈴木崇允など
- Industrial Property Rights Holder
  金井求、相馬洋平、富田泰輔、堀由起子、澤崎鷹、鈴木崇允など
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-195981
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21H02602
[Patent] メチレンブルーを母骨格とする新規光触媒2021
- Inventor(s)
  金井求、相馬洋平、城野柳人、大井未来
- Industrial Property Rights Holder
  金井求、相馬洋平、城野柳人、大井未来
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K22484
[Patent] メチレンブルーを母骨格とする新規光触媒2020
- Inventor(s)
  金井求、相馬洋平、城野柳人、大井未来
- Industrial Property Rights Holder
  金井求、相馬洋平、城野柳人、大井未来
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19K22484
[Patent] 光酸素化触媒化合物及びこれを含有する医薬2020
- Inventor(s)
  金井求、相馬洋平、永島臨、富田泰輔、堀由起子、小澤柊太
- Industrial Property Rights Holder
  金井求、相馬洋平、永島臨、富田泰輔、堀由起子、小澤柊太
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19K22484
[Patent] メチレンブルーを母骨格とする新規光触媒2020
- Inventor(s)
  金井求、相馬洋平、城野柳人、大井未来
- Industrial Property Rights Holder
  金井求、相馬洋平、城野柳人、大井未来
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-16H06216
[Patent] 光酸素化触媒化合物及びこれを含有する医薬2019
- Inventor(s)
  金井求、相馬洋平、永島臨、富田泰輔、堀由起子、小澤柊太
- Industrial Property Rights Holder
  金井求、相馬洋平、永島臨、富田泰輔、堀由起子、小澤柊太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-217947
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K22484
[Patent] 光酸素化触媒化合物及びこれを含有する医薬2019
- Inventor(s)
  金井求、相馬洋平、永島臨、富田泰輔、堀由起子、小澤柊太
- Industrial Property Rights Holder
  金井求、相馬洋平、永島臨、富田泰輔、堀由起子、小澤柊太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-217947
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Catalysis driven by an amyloid-substrate complex2024
- Author(s)
  Youhei Sohma
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] TDP-43の病原性構造基盤の解明に向けた翻訳後修飾体化学合成経路の構築2023
- Author(s)
  佐々木大輔、澤崎鷹、相馬洋平
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] アミロイドを活用した新規触媒系の開発と基質選択的反応への応用2023
- Author(s)
  澤崎鷹，佐々木大輔，相馬洋平
- Organizer
  反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] Chemical Catalysts that Promote Removal of Brain Amyloids2023
- Author(s)
  Youhei Sohma
- Organizer
  The 19th AKABORI Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] アミロイド触媒を利用した基質選択的な変換反応2023
- Author(s)
  澤崎鷹、佐々木大輔、相馬洋平
- Organizer
  第17回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] CATALYSIS DRIVEN BY AMYLOID-SUBSTRATE COMPLEX2023
- Author(s)
  Taka Sawazaki, Daisuke Sasaki, Youhei Sohma
- Organizer
  60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 基質選択的な変換反応を促進できる新規アミロイド触媒系の開発2023
- Author(s)
  澤崎鷹，佐々木大輔，相馬洋平
- Organizer
  第40回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 有機化学反応で細胞内を制御せよ！2023
- Author(s)
  相馬洋平
- Organizer
  第13回CSJ化学フェスタ2023
- Invited
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] アルツハイマー病患者由来のタウアミロイドに対する触媒的光酸素化2023
- Author(s)
  梅田大輝、澤崎鷹、鈴木崇允、古田将大、三ツ沼治信, 川島　茂裕、堀由起子、富田泰輔、相馬洋平、金井求
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] Catalysis driven by an amyloid-substrate complex2023
- Author(s)
  Youhei Sohma and Taka Sawazaki
- Organizer
  ISBOC-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 基質選択的な変換反応を促進できる新規アミロイド触媒系の開発2023
- Author(s)
  澤崎鷹、佐々木大輔、相馬洋平
- Organizer
  日本ケミカルバイオロジー学会第17回年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] Development of Amyloid Breakers: Catalytic Photooxygenation of Transthyretin Amyloids in vivo2023
- Author(s)
  Mina Yamane, Moe Toyobe, Hiroki Umeda, Atsushi Iwai, Genki Kudo, Harunobu Mitsunuma, Masamitsu Okada, Mitsuharu Ueda, Yukio Ando, Takatsugu Hirokawa, Shigehiro Kawashima, Youhei Sohma, Kunitoshi Yamanaka, Motomu Kanai
- Organizer
  国際有機化学京都会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 脳内タウアミロイドの除去を促進する化学触媒2023
- Author(s)
  相馬洋平、澤崎鷹、鈴木崇允、樋口真人、堀由起子、富田泰輔、金井求
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] Non-invasive photo-oxygenation of tau amyloid against tauopathy2023
- Author(s)
  Yukiko Hori, Takanobu Suzuki, Taka Sawazaki, Makoto Higuchi, Youhei Sohma, Motomu Kanai, Taisuke Tomita
- Organizer
  生化学会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] AAアミロイドーシス治療を目指した光酸素化法の検証2023
- Author(s)
  堀由起子、浅井秀一朗、渡邉謙一、相馬洋平、金井求、富田泰輔
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] アミロイドと基質の複合化を起点にする触媒反応の開発2023
- Author(s)
  澤崎鷹、佐々木大輔、相馬洋平
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 生体レベルでの応用を志向した高活性アミロイド光酸素化触媒の開発研究2023
- Author(s)
  古田将大、堀由起子、富田泰輔、相馬洋平、三ツ沼治信、金井求
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 臨床応用を指向した超音波によるAmyloid β酸素化触媒の開発研究2023
- Author(s)
  渥美渉　川畑恵一　大井未来　三ツ沼治信　堀由起子　富田泰輔　相馬洋平　金井求
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 脳内アミロイドタンパク質の除去を促進する化学触媒2023
- Author(s)
  相馬洋平
- Organizer
  大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] パーキンソン病治療戦略を指向したαシヌクレインに対する光酸素化触媒2022
- Author(s)
  岩井篤志、永島臨、中村麗人、富澤郁美、三ツ沼治信、堀由起子、富田泰輔、相馬洋平、金井求
- Organizer
  日本化学会　第102春季年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 脳内のアミロイドタンパク質を除去する化学触媒2022
- Author(s)
  相馬洋平
- Organizer
  令和4 年度有機合成セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] アミロイドに焦点を当てたペプチド化学2022
- Author(s)
  相馬洋平
- Organizer
  第３７回関西地区ペプチドセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 細胞内タウアミロイドを光酸素化する化学触媒の開発2022
- Author(s)
  澤崎鷹, 鈴木崇允, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] Catalytic Photooxygenation of Tau Protein Amyloid2022
- Author(s)
  Youhei Sohma, Taka Sawazaki, Takanobu Suzuki, Yukiko Hori, Taisuke Tomita, Motomu Kanai
- Organizer
  59回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] 臨床応用を指向したトランスサイレチンアミロイドの触媒的光酸素化2022
- Author(s)
  山根三奈、岩井篤志、永島臨、三ツ沼治信、岡田匡充、山中邦俊、植田光晴、安東由喜雄、相馬洋平、金井求
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] タウの凝集アミロイドを対象とした光酸素化触媒の探索2022
- Author(s)
  梅田大輝、澤崎鷹、鈴木崇允、古田将大、三ツ沼治信、堀由起子、富田泰輔、相馬洋平、金井求
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] トランスサイレチンアミロイドに対する光酸素化触媒の開発2021
- Author(s)
  山根三奈、岩井篤志、永島臨、岡田匡充、植田光晴、安東由喜雄、相馬洋平、金井求
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] Chemical Catalyst-Promoted Photooxygenation of Amyloid Peptide In Vivo2021
- Author(s)
  Youhei Sohma, Nozomu Nagashima, Shuta Ozawa, Masahiro Furuta, Miku Oi, Yukiko Hori, Taisuke Tomita, and Motomu Kanai
- Organizer
  58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] アミロイドペプチドを標的とした化学合成から疾患治療戦略の開発まで2021
- Author(s)
  相馬洋平
- Organizer
  TAKEDA Academic salon2021spring
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] メチレンブルー誘導体を基盤とした新規Aβ光酸素化触媒の開発と機能評価2021
- Author(s)
  大井未来、城野柳人、相馬洋平、金井求
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] アミロイドを光酸素化する人工触媒2021
- Author(s)
  相馬洋平
- Organizer
  大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 神経変性疾患治療を目指した生体内人工触媒反応2021
- Author(s)
  相馬洋平
- Organizer
  第５３回若手ペプチド夏の勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] パーキンソン病治療戦略を指向したαシヌクレインに対する光酸素化触媒2021
- Author(s)
  岩井篤志, 永島臨, 中村麗人, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] Development of Blood-Brain Barrier Permeable Oxygenation Catalyst of Amyloid Peptide2021
- Author(s)
  Youhei Sohma
- Organizer
  The 18th AKABORI Conference 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] アミロイドを光酸素化する人工触媒2021
- Author(s)
  相馬洋平
- Organizer
  新潟大学コアステーション「ユビキタスグリーンケミカルエネルギー連携教育研究センター」第11回研究シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] アミロイドβ の凝集を標的とした創薬化学2021
- Author(s)
  相馬洋平
- Organizer
  第40回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02602
[Presentation] Development of Photo-Oxygenation Catalyst for α-Synuclein2020
- Author(s)
  Atsushi Iwai, Nozomu Nagashima, Reito Nakamura, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
- Organizer
  第５７回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 新規光酸素化触媒による非侵襲的光酸素化反応の確立2020
- Author(s)
  堀由起子、永島臨、小澤柊太、相馬洋平、金井求、富田泰輔
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] αシヌクレインに対する新規光酸素化触媒の開発2020
- Author(s)
  岩井篤志, 永島臨, 中村麗人, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 触媒的光酸素化反応によるタウアミロイド形成の阻害2020
- Author(s)
  澤崎鷹、鈴木崇允、清水裕介、根本侑、谷口敦彦、小澤柊太、堀由起子、富田泰輔、相馬洋平、金井求
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] メチレンブルー骨格を基盤とした新規Aβ酸素化触媒の開発2020
- Author(s)
  大井未来、城野柳人、相馬洋平、金井求
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] αシヌクレインに対する新規光酸素化触媒の開発2020
- Author(s)
  岩井篤志、永島臨、中村麗人、堀由起子、富田泰輔、相馬洋平、金井求
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 神経変性疾患治療を目指した生体内人工触媒反応2020
- Author(s)
  相馬洋平
- Organizer
  7th WCCU
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 血液脳関門を透過可能な光酸素化触媒の開発と低侵襲的な脳内アミロイドβ光酸素化2020
- Author(s)
  永島臨, 小澤柊太, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 血液脳関門を透過可能な光酸素化触媒の開発と低侵襲的な脳内アミロイドβ光酸素化2020
- Author(s)
  永島臨, 小澤柊太, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] Inhibition of tau amyloid formation using catalytic photo-oxygenation2019
- Author(s)
  Taka Sawazaki, Takanobu Suzuki, Yusuke Shimizu, Yu Nemoto, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 触媒的光酸素化はタウのアミロイド形成を阻害する2019
- Author(s)
  澤崎鷹、鈴木崇允、清水裕介、根元侑、谷口敦彦、小澤柊太、堀由紀子、富田泰輔、相馬洋平、金井求
- Organizer
  日本ケミカルバイオロジー学会　第14 回年会
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 疾患原因アミロイドに対する光酸素化触媒の開発～化学・位置・標的選択的なペプチド化学変換～2019
- Author(s)
  相馬洋平
- Organizer
  有機合成化学協会関東支部若手研究者のためのセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 高機能性色素の開発を指向したBオルガノBODIPYの収束的合成法の確立2019
- Author(s)
  澤崎鷹, 清水裕介, 生長幸之助, 相馬洋平, 金井求
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 疾患原因アミロイドに対する光酸素化触媒の開発2019
- Author(s)
  相馬洋平
- Organizer
  有機合成化学協会関東支部　2019年度若手研究者のためのセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 神経変性疾患治療を目指した生体内人工触媒反応2019
- Author(s)
  相馬洋平
- Organizer
  第36回関西地区ペプチドセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] B-オルガノBODIPYの官能基許容性に優れた収束的合成法の開発2019
- Author(s)
  澤崎鷹, 清水裕介, 生長幸之助, 相馬洋平, 金井求
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Development of Blood-Brain Barrier Permeable Oxygenation Catalyst of Amyloid β2019
- Author(s)
  Nozomu Nagashima, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Youhei Sohma, and Motomu Kanai
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] タウのアミロイド形成を阻害する光酸素化触媒の開発2019
- Author(s)
  澤崎鷹, 鈴木崇允, 清水裕介, 根本侑, 谷口敦彦, 小澤柊太, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] INHIBITION OF TAU AMYLOID FORMATION USING CATALYTIC PHOTOOXYGENATION2019
- Author(s)
  Taka Sawazaki, Takanobu Suzuki, Yusuke Shimizu, Yu Nemoto, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Catalytic photo-oxygenation enables inhibition of tau amyloid formation2019
- Author(s)
  Taka Sawazaki, Takanobu Suzuki, Yusuke Shimizu, Yu Nemoto, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 疾患治療を志向した改良型アミロイドβ酸素化触媒の開発2019
- Author(s)
  永島臨、小澤柊太、堀由起子、富田泰輔、相馬洋平、金井求
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Development of Blood-Brain Barrier Permeable Oxygenation Catalyst of Amyloid beta2019
- Author(s)
  Nozomu Nagashima, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] Chemo- and site-selective chemical transformations of peptides and proteins2019
- Author(s)
  Youhei Sohma
- Organizer
  第19回日本蛋白質科学会年会第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] Catalytic photo-oxygenation enables inhibition of tau amyloid formation2019
- Author(s)
  Taka Sawazaki, Takanobu Suzuki, Yusuke Shimizu, Yu Nemoto, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kanai
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Chemo-, Site-, and Target-selective Chemical Transformations of Peptides and Proteins2019
- Author(s)
  Youhei Sohma
- Organizer
  第１９回日本蛋白質科学会年会　第７１回日本細胞生物学会大会　合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 化学・位置・標的選択的なペプチド化学変換2019
- Author(s)
  相馬洋平
- Organizer
  大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 化学・位置・標的選択的なペプチド化学変換2019
- Author(s)
  相馬洋平
- Organizer
  大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] 神経変性疾患治療を目指した生体内人工触媒反応2019
- Author(s)
  相馬洋平
- Organizer
  第7回千葉大学キラリティーネットワーク研究会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 触媒的光酸素化はタウのアミロイド形成を阻害する2019
- Author(s)
  澤崎鷹、鈴木崇允、清水裕介、根元侑、谷口敦彦、小澤柊太、堀由紀子、富田泰輔、相馬洋平、金井求
- Organizer
  日本ケミカルバイオロジー学会　第14回年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 生体適用を志向したメチレンブルー型Aβ光酸素化触媒の開発2019
- Author(s)
  城野柳人, 大井未来, 相馬洋平, 金井求
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 神経変性疾患治療を目指した生体内人工触媒反応2019
- Author(s)
  相馬洋平
- Organizer
  第36回関西地区ペプチドセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K22484
[Presentation] タウのアミロイド形成を阻害する光酸素化触媒の開発2019
- Author(s)
  澤崎鷹, 鈴木崇允, 清水裕介, 根本侑, 谷口敦彦, 小澤柊太, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  第３７回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] メチレンブルーを母骨格としたアミロイドβ選択的な光酸素化触媒の開発2018
- Author(s)
  城野柳人、相馬洋平、金井求
- Organizer
  日本ケミカルバイオロジー学会　第13回年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Artificial Chemical Transformation of Amyloid Peptide by Catalytic Photo-Oxygenation2018
- Author(s)
  Youhei Sohma, Jizhi Ni, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Motomu Kanai
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 凝集タウ蛋白質を標的とした光酸素化触媒の開発2018
- Author(s)
  澤崎鷹, 鈴木崇允, 根本侑, 小澤柊太, 倪積智, 堀由起子, 富田泰輔, 相馬洋平, 金井求
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] アルツハイマー病の原因物質の構造解明を指向した安定なアミロイドβオリゴマーの合成2018
- Author(s)
  篠田清道, 相馬洋平, 金井求
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Artificial chemical transformations of peptides and proteins2018
- Author(s)
  Youhei Sohma
- Organizer
  Stephen Kent Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] ヒドロキシ基を配向基としたアミドの触媒的ヒドロシリル化2018
- Author(s)
  Jizhi Ni, Tsubasa Oguro, Youhei Sohma, Motomu Kanai
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Development of drug discovery frontier integrated peptide chemistry and catalysis2018
- Author(s)
  Youhei Sohma
- Organizer
  Second Japanese-Spanish Post-Symposium in Organic Synthesis in Tokyo
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Near-infrared photoactivatable oxygenation catalyst of amyloid peptide2018
- Author(s)
  Youhei Sohma, Jizhi Ni, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Motomu Kanai
- Organizer
  35th European Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Near-infrared Photoactivatable Oxygenation Catalysts of Amyloid Peptide2018
- Author(s)
  Youhei Sohma, Jizhi Ni, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Motomu Kanai
- Organizer
  Akabori conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] メチレンブルーを母骨格としたアミロイドβ選択的な光酸素化触媒の開発2018
- Author(s)
  城野柳人, 相馬洋平金井求
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] ホウ素上に多様な官能基を有するBODIPYの収束的合成法の開発2018
- Author(s)
  澤崎鷹, 清水裕介, 相馬洋平, 金井求
- Organizer
  第48回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 凝集タウ蛋白質を標的とした光酸素化触媒の開発2018
- Author(s)
  澤崎鷹、鈴木崇允、根本侑、小澤柊太、倪積智、堀由起子、富田泰輔、相馬洋平、金井求
- Organizer
  日本ケミカルバイオロジー学会　第13回年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Development of near-infrared photoactivatable amyloid-selective oxygenation catalyst and application to the disease-model mouse2018
- Author(s)
  Youhei Sohma, Jizhi Ni, Atsuhiko Taniguchi, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Motomu Kanai
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] アミロイドタンパク質に対する革新的凝集阻害戦略の開発2017
- Author(s)
  相馬洋平
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] 近赤外光で励起可能なアミロイド選択的光酸素化触媒の開発と疾患モデルマウスへの応用2017
- Author(s)
  谷口敦彦、倪積智、國信洋一郎、小澤柊太、堀由起子、斉藤貴志、西道隆臣、富田泰輔、相馬洋平、金井求
- Organizer
  日本ケミカルバイオロジー学会第12回年会
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Biochemical analysis of oxygenated Ab by photo oxygenation system2017
- Author(s)
  Yukiko Hori, Shuta Ozawa, Atsuhiko Taniguchi, Yusuke Shimizu, Ryuto Kino, Takashi Saito, Takaomi C. Saido, Youhei Sohma, Motomu Kanai, Taisuke Tomita
- Organizer
  Neuroscience 2007
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] アミロイドタンパク質に対する革新的凝集阻害戦略の開発2017
- Author(s)
  相馬洋平
- Organizer
  千葉大学大学院薬学研究科講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Biocompatible Photooxygenation Catalyst that Targets Amyloid Aggregation2017
- Author(s)
  Youhei Sohma
- Organizer
  23rd Peptide Forum
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2017-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Transitition Metal-Free, Tryptophane-Selective Bioconjugation of Proteins2017
- Author(s)
  Kounosuke Oisaki, Yohei Seki, Takashi Ishiyama, Daisuke Sasaki, Junpei Abe, Youhei Sohma, Motomu Kanai
- Organizer
  Shimadzu Global Innovation Summit 2017
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] アミロイドタンパク質に対する革新的凝集阻害戦略の開発2017
- Author(s)
  相馬洋平
- Organizer
  日本薬学会　第１３７年会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Rational design and synthesis of non-peptidic aggregation inhibitors based on primary structure of amyloid β2016
- Author(s)
  Takushi Araya, Ryuto Kkino, Youhei Sohma, Motomu Kanai
- Organizer
  French-Japanese Symposium on Medicinal and Fine Chemistry
- Place of Presentation
  京王プラザホテル多摩（東京都・多摩）
- Year and Date
  2016-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] In vivo への適用を目指したアミロイドβ選択的光酸素化触媒の開発2016
- Author(s)
  谷口敦彦、清水裕介、倪　積智、生長幸之助、國信洋一郎、相馬洋平、金井　求
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] アミロイドタンパク質に対する革新的凝集阻害戦略の開発2016
- Author(s)
  相馬洋平
- Organizer
  明治薬科大学認知症創薬資源研究開発センター講演会
- Place of Presentation
  明治薬科大学（東京都・清瀬市）
- Year and Date
  2016-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Synthesis of Amyloid-β Oligomer Models Possessing Various Numbers of Amyloid-β Segment Chains2016
- Author(s)
  Kiyomichi Shinoda, Youhei Sohma, Motomu Kanai
- Organizer
  Molecular Chirality Asia
- Place of Presentation
  コングレコンベンションセンター（大阪府・大阪市）
- Year and Date
  2016-04-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Synthesis of Amyloid-β Oligomer Models Possessing Various Numbers of Amyloid-β Segment Chains2016
- Author(s)
  Kiyomichi Shinoda, Youhei Sohma, Motomu Kanai
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] ペプチド由来ファーマコフォアを有する新規アミロイドβ凝集阻害低分子化合物の創成2016
- Author(s)
  新谷卓士、城野柳人、相馬洋平、金井求
- Organizer
  第４６回複素環化学討論会
- Place of Presentation
  金沢歌劇座（石川県・金沢市）
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] アミロイドペプチドの凝集を標的とした機能分子設計2016
- Author(s)
  相馬洋平
- Organizer
  第８９回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] アミロイド疾患の治療を指向した選択的光酸素化触媒の開発2016
- Author(s)
  相馬洋平，谷口敦彦，倪　積智，清水裕介，生長幸之助，小澤　柊太、堀由起子、富田泰輔、金井求
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Amyloid-selective catalytic photooxygenation with long-wavelength light irradiation2016
- Author(s)
  Atsuhiko Taniguchi, Jizhi Ni, Yusuke Shimizu, Shuta Ozawa, Yukiko Hori, Taisuke Tomita, Kounosuke Oisaki, Yoichiro Kuninobu, Youhei Sohma, Motomu Kanai
- Organizer
  Peptide and Protein Society in Singapore Symposium
- Place of Presentation
  南洋（シンガポール）
- Year and Date
  2016-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Transition Metal-Free Tryptophan-Selective Bioconjugation of Proteins2016
- Author(s)
  Takashi Ishiyama, Yohei Seki, Daisuke Sasaki, Junpei Abe, Youhei Sohma, Kounosuke Oisaki, Motomu Kanai
- Organizer
  第33回有機合成化学セミナー
- Place of Presentation
  ヒルトンニセコビレッジ（北海道・虻田郡ニセコ町）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Development of near-infrared photoactivatable oxygenation catalysts that sense amyloid structure2016
- Author(s)
  Atsuhiko Taniguchi, Jizhi Ni, Youhei Sohma, Motomu Kanai
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] Serine-Selective Aerobic Cleavage of Peptides and a Protein Using Water-Soluble Copper-Organoradical Conjugate2016
- Author(s)
  Yohei Seki, Kana Tanabe, Daisuke Sasaki, Youhei Sohma, Kounosuke Oisaki, Motomu Kanai
- Organizer
  17th Tetrahedron Symposium
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] ペプチド由来ファーマコフォアを有する新規アミロイドβ凝集阻害低分子化合物の創成2016
- Author(s)
  新谷卓士, 城野柳人，西光海，藤後貴也，國信洋一郎，相馬洋平，金井求
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H06216
[Presentation] ネイティブケミカルライゲーション法を利用したO-アシルイソペプチドの合成2011
- Author(s)
  相馬洋平、北村仁美、川島浩之、北條裕信、赤路健一、木曽良明
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] アミロイドベータペプチドおよびアミリンの凝集機構解明を目指したO-アシルイソペプチドの利用2011
- Author(s)
  相馬洋平Hui Wang山崎萌,平山雄太,谷口敦彦,川島浩之,比嘉彩乃,吉矢拓,向井秀仁,木曽良明
- Organizer
  第9回次世代を担う有機化学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] エステル含有ペプチドを基盤とした生物有機化学研究2011
- Author(s)
  相馬洋平
- Organizer
  第46回天然物化学談話会
- Place of Presentation
  熱川
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] Use of O-acyl isopeptides to identify new functions of amyloid beta peptides2010
- Author(s)
  Youhei Sohma, Atsuhiko Taniguchi, Yuta Hirayama, Hui Wang, Moe Yamazaki, Hidehito Mukai, Yoshiaki Kiso
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] エルテルまたはチオエステルを含むペプチド合成法開発とその生物研究への応用2010
- Author(s)
  相馬洋平,Stephen B. H. Kent,木曽良明
- Organizer
  第8回次世代を担う有機化学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] アミロイドベータペプチドの機能解明を目指したO-アシルイソペプチドの利用.2010
- Author(s)
  相馬洋平、平山雄太、谷口敦彦、向井秀仁、木曽良明
- Organizer
  第36回反応と合成の進歩シンポジウム-ライフサイエンスを志向した理論、反応および合成-
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21249007
[Presentation] アミロイドβペプチドおよびインスリンの機能解明を目指したエステル含有ペプチドの利用.2010
- Author(s)
  相馬洋平、谷口敦彦、向井秀仁、StephenKent、木曽良明
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21249007
[Presentation] Use of ester-containing peptides toward understanding the functions of amyloid beta peptide and human insulin.2010
- Author(s)
  Youhei Sohma
- Organizer
  31st European Peptides Symposium
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] "クリックペプチド":水溶性プレカーサーによるアルツハイマー病関連Aβ変異体の産生.2010
- Author(s)
  王惠、柿澤多惠子、谷口敦彦、水口貴章、相馬洋平、向井秀仁、木村徹、木曽良明
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21249007
[Presentation] アミロイドβペプチドおよびインスリンの機能解明を目指したエステル含有ペプチドの利用2010
- Author(s)
  相馬洋平
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] Use of O-Acyl isopeptides to identify new functions of amyloid beta peptides.2010
- Author(s)
  Youhei Sohma
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] アミロイドβペプチドおよびインスリンの機能解明を目指したエステル含有ペプチドの利用2010
- Author(s)
  相馬洋平、谷口敦彦、向井秀仁、Stephen B. H. Kent、木曽良明
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] Use of O-acyl isopeptides to identify new functions of amyloid beta peptides2010
- Author(s)
  Youhei Sohma, Atsuhiko Taniguchi, Yuta Hirayama, Hui Wang, Moe Yamazaki, Hidehito Mukai, Yoshiaki Kiso
- Organizer
  31st European Peptides Symposium
- Place of Presentation
  Copenhagen,Denmark
- Year and Date
  2010-09-05
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] Use of ester-containing peptides for identifying the functions of human insulin and amyloid peptide.2010
- Author(s)
  Youhei Sohma
- Organizer
  大阪大学蛋白質研究所セミナーNew Trend of Peptide Science in Asia and Oceania
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] Use of ester-containing peptides for identifying the functions of human insulin and amyloid peptide2010
- Author(s)
  Youhei Sohma
- Organizer
  大阪大学蛋白質研究所セミナーNew Trend of Peptide Science in Asia and Oceania
- Place of Presentation
  大阪
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790118
[Presentation] Use of ester-containing peptides toward understanding the functions of amyloid beta peptide and human insulin.2010
- Author(s)
  Y.Sohma
- Organizer
  31st European Peptide Symposium
- Place of Presentation
  コペンハーゲン、デンマーク
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21249007
[Presentation] In situ production of Alzheimer's Aβ mutants from water-soluble click peptide precursors.2010
- Author(s)
  Hui Wang, Taeko Kakizawa, Atsuhiko Taniguchi, Takaaki Mizuguchi, Youhei Sohma, Hidehito Mukai, Tooru Kimura, Yoshiaki Kiso
- Organizer
  11th Chinese International Peptide Symposium
- Place of Presentation
  Lanzhou, China
- Data Source
  KAKENHI-PROJECT-21249007
[Presentation] In situ production of Alzheimer's disease-related amyloid s peptide from water- soluble precursor analogs.2009
- Author(s)
  Atsuhiko Taniguchi, Youhei Sohma, Mariusz Skwarczynski, Yuta Hirayama, Takuma Okada, Keisuke Ikeda, Halan Prakash, Hidehito Mukai, Tooru Kimura, Yoshio Hayashi, Shun Hirota, Katsumi Matsuzaki, Yoshiaki Kiso: Click peptide
- Organizer
  238th American Chemical Society National Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-21249007

1. KISO Yoshiaki (40089107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
2. KIMURA Tooru (70204980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. MUKAI Hidehito (20251027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. HIDAKA Koushi (30445960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 澤崎鷹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 生長幸之助

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 三ツ沼治信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 堀由起子

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
9. 富田泰輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
10. 金井求

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
11. 谷口敦彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sohma Youhei 相馬 洋平

SOHMA Youhei 相馬 洋平

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アミロイドを解明・治療・利用する化学研究Principal Investigator

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TDP-43アミロイドに対する特異的リガンドの創製プラットフォームの構築Principal Investigator

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Development of innovative aggregation inhibition strategies for amyloid proteins that cause neurodegenerative diseasesPrincipal Investigator

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Control of intracellular amyloid dynamics using photooxygenation catalystsPrincipal Investigator

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Development of aggregation inhibition strategy for pathogenic amyloid proteinsPrincipal Investigator

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Research on pathological mechanism of amyloid beta peptide and application to the aggregation inhibitorPrincipal Investigator

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Design and Medicinal Chemistry Research on Therapeutics ofDifficult Diseases based on Molecular Recognition

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[Book] 遺伝子医学MOOK21号最新ペプチド合成技術とその創薬研究への応用(木曽良明編集)O-アシルイソペプチドの合成.2012

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[Book] ペプチド医薬の最前線2012

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[Book] 最新ペプチド合成技術とその創薬研究への応用2011

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[Book] Wiley Encyclopedia of Chemical Biology, Volume 1 (Tadhg P. Begley, Chief Advisor)2009

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[Journal Article] Rose Bengal Promoted Catalytic Amyloid-β Oxygenation by Sonoactivation2023

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[Journal Article] Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins2023

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[Journal Article] Photo‐oxygenation of histidine residue inhibits α‐synuclein aggregation2023

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[Journal Article] Attenuation of α-synuclein aggregation by catalytic photo-oxygenation2023

Author(s)

Sohma Youhei 相馬洋平

SOHMA Youhei 相馬洋平