ose naoko 大瀬尚子

Researcher Number	10570559
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院医学系研究科, 講師 2022 – 2024: 大阪大学, 大学院医学系研究科, 助教 2018 – 2021: 大阪大学, 医学系研究科, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 50010:Tumor biology-related / Respiratory surgery
Keywords	Except Principal Investigator 肺移植 / 慢性閉塞性肺疾患 / 癌関連線維芽細胞 / 肺癌 / 虚血再灌流障害 / 薬剤スクリーニング / 特発性間質性肺炎 / 腫瘍微小環境 / 上皮間葉移行 / 腫瘍免疫 … More / 細胞死 / 幹細胞 / 脂肪幹細胞 / 肺再生 / M2マクロファージ / 虚血再灌流肺障害 / 胸腺癌 / 胸腺腫 / 多細胞系癌体外モデル / 空間プロテオゲノミクス / 心停止 / 肺胞マクロファージ / 移植免疫 / 肺胞上皮細胞 / 脂肪組織由来幹細胞 / 細胞移植治療 / 免疫抑制 / 補体反応 / 拒絶反応 / バイオバンク / 個別化医療 / 難治性呼吸器疾患 / オルガノイド / オルガノイド培養技術 / 悪性腫瘍 / 微小環境 / ペリオスチン / 癌微小環境 / 癌周囲微小環境 / Layer by Layer法 / 細胞培養技術 / 細胞シート / 細胞治療 / 脂肪組織由来間葉系幹細胞 / 肺再生医療 / 再生医療 / iPS細胞 / 呼吸不全 / 急性呼吸窮迫症候群 / 肺線維症 / 人工多機能性幹細胞 Less

Development of Novel Therapeutics for Lung Cancer Targeting the Cancer-Associated Fibroblast-Mediated Tumor Microenvironment Network
- Principal Investigator
  
  新谷康
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Osaka
Exploring the mechanism of malignant transformation of thymoma/thymic carcinoma using organoid methods
- Principal Investigator
  
  永田秀樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Osaka
虚血再灌流肺障害におけるM2マクロファージの治療効果
- Principal Investigator
  
  田中諒
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Osaka
肺移植後慢性拒絶反応における補体反応の機能解明と新規免疫学的治療の開発
- Principal Investigator
  
  池晃弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
Development of new lung regeneration therapies by elucidating the lung regeneration mechanism of adipose tissue-derived stem cells
- Principal Investigator
  
  福井絵里子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
The role of alveolar macrophages and regulatory pathways in post-transplant lung inflammation.
- Principal Investigator
  
  櫻井禎子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
本邦での心停止ドナー肺移植開始を目指したネクロプトーシス制御による臓器保護戦略
- Principal Investigator
  
  狩野孝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
ペリオスチンを基軸とした間質性肺炎合併肺癌に対する包括的治療法の開発
- Principal Investigator
  
  舟木壮一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
肺がんにおける癌関連線維芽細胞の機能解析と新規治療戦略の提案
- Principal Investigator
  
  磯野友美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
The investigation of molecular mechanisms underlying refractory respiratory diseases using human lung derived organoids
- Principal Investigator
  
  新谷康
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka University
Development of novel treatment strategy against ischemia reperfusion lung injury after lung transplantation via the inhibition of necroptosis.
- Principal Investigator
  
  Kanou Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
Regenerating medicine using multilayered tissues with adipose derived stem cell for COPD
- Principal Investigator
  
  Shintani Yasushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka University
Perspective of targeting cancer-associated fibroblasts in non-small-cell lung cancer
- Principal Investigator
  
  Shintani Yasushi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
Stem cell based therapy for lung regeneration
- Principal Investigator
  
  Okumura Meinoshin
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] A Novel Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-Kappa B Activation Pathway is Involved in the Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemia-Reperfusion Lung Injury2024
- Author(s)
  Miyashita Yudai、Kanou Takashi、Fukui Eriko、Matsui Takahiro、Kimura Toru、Ose Naoko、Funaki Soichiro、Shintani Yasushi
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 56 Issue: 2 Pages: 369-379
- DOI
  10.1016/j.transproceed.2024.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08293
[Journal Article] Therapeutic Targeting of Cancer-Associated Fibroblasts in the Non-Small Cell Lung Cancer Tumor Microenvironment.2023
- Author(s)
  Shintani Y, Kimura T, Funaki S, Ose N, Kanou T, Fukui E.
- Journal Title
  
  Cancers (Basel).
  
  Volume: 15 Issue: 2 Pages: 335-353
- DOI
  10.3390/cancers15020335
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03745
[Journal Article] Periostin secreted by activated fibroblasts in idiopathic pulmonary fibrosis promotes tumorigenesis of non-small cell lung cancer2021
- Author(s)
  Yamato Hiroyuki、Kimura Kenji、Fukui Eriko、Kanou Takashi、Ose Naoko、Funaki Soichiro、Minami Masato、Shintani Yasushi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 21114-21114
- DOI
  10.1038/s41598-021-00717-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17745, KAKENHI-PROJECT-19H03745
[Journal Article] Effects of pirfenidone targeting the tumor microenvironment and tumor-stroma interaction as a novel treatment for non-small cell lung cancer2020
- Author(s)
  Fujiwara Ayako、Funaki Soichiro、Fukui Eriko、Kimura Kenji、Kanou Takashi、Ose Naoko、Minami Masato、Shintani Yasushi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 10900-10900
- DOI
  10.1038/s41598-020-67904-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03745
[Journal Article] Adipose Tissue-Derived Stem Cells Have the Ability to Differentiate into Alveolar Epithelial Cells and Ameliorate Lung Injury Caused by Elastase-Induced Emphysema in Mice.2019
- Author(s)
  Fukui E, Funaki S, Kimura K, Momozane T, Kimura A, Chijimatsu R, Kanzaki R, Kanou T, Ose N, Minami M, Miyagawa S, Sawa Y, Okumura M, Shintani Y.
- Journal Title
  
  Stem Cells Int.
  
  Volume: － Pages: 5179172-5179172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04296
[Journal Article] The prognostic impact of programmed cell death 1 and its ligand and the correlation with epithelial-mesenchymal transition in thymic carcinoma.2019
- Author(s)
  Funaki S, Shintani Y, Fukui E, Yamamoto Y, Kanzaki R, Ose N, Kanou T, Minami M, Mori E, Okumura M.
- Journal Title
  
  Cancer Med.
  
  Volume: 8 Issue: 1 Pages: 216-226
- DOI
  10.1002/cam4.1943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] 難治性呼吸器疾患に対する肺移植と再生医療2024
- Author(s)
  新谷康、舟木壮一郎、大瀬尚子、狩野孝、木村亨、福井絵里子
- Organizer
  日本再生医療学会(23)
- Data Source
  KAKENHI-PROJECT-22K19560
[Presentation] 脂肪組織由来幹細胞を用いた肺再生医療2023
- Author(s)
  新谷康、舟木壮一郎、福井絵里子、大瀬尚子、狩野孝、木村亨、宮下祐大、宮川繁、澤芳樹
- Organizer
  日本再生医療学会(22)
- Data Source
  KAKENHI-PROJECT-22K19560
[Presentation] Development of Lung Regenerative Medicine Using Adipose Tissue-derived Stem Cells2022
- Author(s)
  福井絵里子、宮下裕大、木村亨、狩野孝、大瀬尚子、舟木壮一郎、新谷康
- Organizer
  日本胸部外科学会定期学術集会(75)
- Data Source
  KAKENHI-PROJECT-22K19560
[Presentation] Fibroblast activation protein-α発現がん関連線維芽細胞とT細胞性免疫との関係2022
- Author(s)
  磯野友美、岩堀幸太、福井絵里子、木村亨、狩野孝、大瀬尚子、舟木壮一郎、和田尚、新谷康
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09000
[Presentation] Therapeutic targeting of cancer-associated fibroblasts in non-small-cell lung cancer tumor microenvironment2022
- Author(s)
  Shintani Y, Kimura T, Funaki S, Ose N, Kanou T, Fukui E.
- Organizer
  日本外科学会定期学術総会(122)
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] Fibroblast activationprotein-α発現がん関連線維芽細胞とT細胞性免疫との関係2022
- Author(s)
  磯野友美、岩堀幸太、福井絵里子、木村亨、狩野孝、大瀬尚子、舟木壮一郎、和田尚、新谷康
- Organizer
  日本肺癌学会学術集会(63)
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] 肺の組織常在性マクロファージと肺癌細胞との相互作用の解明2022
- Author(s)
  谷口聖治、松井崇浩、福井絵里子、木村亨、狩野孝、大瀬尚子、舟木壮一郎、新谷康、石井優
- Organizer
  日本肺癌学会学術集会(63)
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] 特発性肺線維症(IPF)合併肺癌の悪性化とPeriostin(POSTN)との関連2021
- Author(s)
  大和寛幸、木村賢二、福井絵里子、狩野孝、大瀬尚子、舟木壮一郎、南正人、新谷康
- Organizer
  日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] Periostin(POSTN)は特発性肺線維症合併肺癌の悪性化に関わる2021
- Author(s)
  大和寛幸、木村賢二、福井絵里子、狩野孝、大瀬尚子、舟木壮一郎、南正人、新谷康
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] 肺癌細胞と肺胞マクロファージとの相互作用の解明2021
- Author(s)
  谷口聖治、松井崇浩、木村賢二、福井絵里子、狩野孝、大瀬尚子、舟木壮一郎、南正人、新谷康、石井優
- Organizer
  日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] 脂肪組織由来幹細胞を用いた難治性呼吸器疾患に対する肺再生治療法の研究2020
- Author(s)
  福井絵里子、宮下裕大、木村賢二、狩野　孝、大瀬尚子、舟木壮一郎、南　正人、宮川　繁、澤　芳樹、新谷　康
- Organizer
  日本胸部外科学会定期学術集会(73)
- Data Source
  KAKENHI-PROJECT-19K22659
[Presentation] 交互積層細胞コーティングを用いたinVitro三次元肺間質モデル2019
- Author(s)
  久能英法、新谷　康、　赤木隆美、福井絵里子、　狩野　孝、大瀬尚子、舟木壮一郎、南　正人、明石　満
- Organizer
  第36回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-17H04296
[Presentation] 難治性肺疾患に対する肺再生治療2019
- Author(s)
  新谷　康、舟木壮一郎、桃實　徹、福井絵里子、久能英法、大瀬尚子、狩野　孝、神崎　隆、南　正人、宮川　繁、澤　芳樹、奥村明之進
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17H04296
[Presentation] 難治性肺疾患に対する肺再生治療2019
- Author(s)
  新谷　康、舟木壮一郎、桃實　徹、福井絵里子、久能英法、大瀬尚子、狩野　孝、神崎　隆、南　正人、宮川　繁、澤　芳樹、奥村　明之進
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K22659
[Presentation] 慢性閉塞性肺疾患に対する肺再生治療2019
- Author(s)
  新谷　康、舟木壮一郎、桃實　徹、福井絵里子、久能英法、大瀬尚子、狩野　孝、神崎　隆、南　正人、宮川　繁、澤　芳樹、奥村　明之進
- Organizer
  第55回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-19K22659
[Presentation] 交互積層細胞による生体外三次元肺微小血管モデルの構築2019
- Author(s)
  久能英法、新谷　康、　赤木隆美、福井絵里子、　狩野　孝、大瀬尚子、舟木壮一郎、南　正人、明石　満
- Organizer
  第72回日本胸部外科学会総会
- Data Source
  KAKENHI-PROJECT-19K22659
[Presentation] 交互積層細胞コーティングを用いたinVitro三次元肺間質モデル2019
- Author(s)
  久能英法、新谷　康、　赤木隆美、福井絵里子、　狩野　孝、大瀬尚子、舟木壮一郎、南　正人、明石　満
- Organizer
  第36回日本呼吸器外科学会
- Data Source
  KAKENHI-PROJECT-19K22659
[Presentation] 交互積層細胞による生体外三次元肺微小血管モデルの構築2019
- Author(s)
  久能英法、新谷　康、　赤木隆美、福井絵里子、　狩野　孝、大瀬尚子、舟木壮一郎、南　正人、明石　満
- Organizer
  第72回日本胸部外科学会総会
- Data Source
  KAKENHI-PROJECT-17H04296
[Presentation] The role of Arl4c in the carcinogenesisi process of lung adenocarcinoma2019
- Author(s)
  Kimura K, Matsumoto S, Fukui E, Kanou T, Ose N, Funaki S, Shintani Y, Kikuchi A
- Organizer
  World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] Therapeutic targeting of non-small-cell lung cancer tumor microenvironment2019
- Author(s)
  新谷　康、舟木壮一郎、大瀬尚子、狩野　孝、福井絵里子、木村賢二、大和寛幸、南　正人
- Organizer
  第72回日本胸部外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03745
[Presentation] 慢性閉塞性肺疾患に対する肺再生治療2019
- Author(s)
  新谷　康、舟木壮一郎、桃實　徹、福井絵里子、久能英法、大瀬尚子、狩野　孝、神崎　隆、南　正人、宮川　繁、澤　芳樹、奥村明之進
- Organizer
  第55回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-17H04296
[Presentation] Construction of 3-dimentional lung interstitial model using Layer-by-Layer cell coating technique2018
- Author(s)
  Kunou H, Shintani Y, Minami M, Funaki S, Ose N, Kano T, Kanzaki R, Sawa Y
- Organizer
  第71回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17H04296
[Presentation] 脂肪組織由来幹細胞の肺気腫モデルマウスに対する治療効果とその役割2018
- Author(s)
  福井絵里子、新谷康、神崎隆、狩野孝、大瀬尚子、舟木壮一郎、南正人、宮川繁、澤芳樹、奥村明之進
- Organizer
  第71回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17H04296
[Presentation] Adipose derived-stem cells show ability to differentiate into alveolar epithelial cells and ameliorate elastase-induced emphysema in model mice2018
- Author(s)
  Fukui E, Shintani Y, Kimura K, Momozane T, Kanzaki R, Kano T, Ose N, Funaki S, Minami M, Okumura M
- Organizer
  International Society for Stem Cell Reserch
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04296
[Presentation] 肺障害修復過程における脂肪組織由来幹細胞の役割2018
- Author(s)
  福井絵里子、新谷康、桃實徹、神崎隆、大瀬尚子、川村知裕、舟木壮一郎、南正人、奥村明之進
- Organizer
  第35回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-17H04296

1. Kanou Takashi (70528455)

# of Collaborated Projects: 14 results

# of Collaborated Products: 27 results
2. Shintani Yasushi (90572983)

# of Collaborated Projects: 14 results

# of Collaborated Products: 30 results
3. 舟木壮一郎 (50464251)

# of Collaborated Projects: 11 results

# of Collaborated Products: 30 results
4. 福井絵里子 (90814591)

# of Collaborated Projects: 9 results

# of Collaborated Products: 5 results
5. 木村亨 (90580796)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
6. 南正人 (10240847)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
7. 木村賢二 (50795325)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. Okumura Meinoshin (40252647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 神崎隆 (10779060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. 川村知裕 (30528675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 磯野友美 (00869282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 池晃弘 (50982021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 前田晃 (00319708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 櫻井禎子 (80760496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 辻川和丈 (10207376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 永田秀樹 (80910744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 田中諒 (71002838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大和寛幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ose naoko 大瀬 尚子

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[Journal Article] A Novel Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-Kappa B Activation Pathway is Involved in the Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemia-Reperfusion Lung Injury2024

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[Journal Article] Therapeutic Targeting of Cancer-Associated Fibroblasts in the Non-Small Cell Lung Cancer Tumor Microenvironment.2023

ose naoko 大瀬尚子