Nagatomo Izumi 長友泉

… Alternative Names

NAGATOMO Izumi 長友泉

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Researcher Number	10570583
Other IDs
Affiliation (Current)	2025: 大阪大学, キャンパスライフ健康支援・相談センター, 教授 2025: 大阪大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2024: 大阪大学, キャンパスライフ健康支援・相談センター, 教授 2021: 大阪大学, キャンパスライフ健康支援・相談センター, 教授 2020: 大阪大学, キャンパスライフ健康支援センター, 教授 2019: 大阪大学, 医学系研究科, 講師 2014: 大阪大学, 大学院医学系研究科, 助教 … More 2012 – 2014: 大阪大学, 医学(系)研究科(研究院), 助教 2012: 大阪大学, 大学院・医学系研究科, 特任助教(常勤) 2011: 大阪大学, 医学(系)研究科(研究院), 特任助教(常勤) Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator 細胞老化 / ミトコンドリア動態 / EGFR遺伝子変異陽性肺癌 / 肺癌薬物療法 / がん免疫 / セマフォリン / EML4-ALK陽性肺癌 / 分子標的治療薬 / 薬剤耐性 / 肺癌 … More Except Principal Investigator … More ＨＥＲ２ / ベバシズマブ / ICAM-1 / ADCC / トラスツズマブ / ラパチニブ / HER2 / 分子標的治療 / 多剤耐性 / 小細胞肺癌 / 肺がん / がんワクチン / 免疫療法 / 胸部悪性疾患 / ヘルパー / 癌免疫 / ヘルパーペプチド / ヘルパーTリンパ球 / 癌免疫療法 / 癌ワクチン / Th17 / 癌抗原 / ペプチドワクチン / CTL / T細胞レセプター / 悪性腫瘍 / 免疫治療 / WT1 Less

ミトコンドリア動態を鍵因子とする、細胞老化制御と発癌抑制の両立Principal Investigator
- Principal Investigator
  
  長友泉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka University
Development of novel therapeutic strategies for EGFR mutation-positive lung cancer by targeting semaphorin 7APrincipal Investigator
- Principal Investigator
  
  Nagatomo Izumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Osaka University
Development of WT1 peptide-based immunotherapy for inoperable thoracic malignant tumors, and analysis of immunodynamics of the novel therapy
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
HER2 target therapy for multidrug-resistant small cell lung cancer
- Principal Investigator
  
  KIJIMA TAKASHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Identifying and overcoming mechanisms of ALK tyrosine kinase inhibitor resistance in lung cancer cells bearing EML4-ALK gene fusions.Principal Investigator
- Principal Investigator
  
  NAGATOMO Izumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University

All 2021 2020 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] IL-33 Induces Sema4A Expression in Dendritic Cells and Exerts Antitumor Immunity2021
- Author(s)
  Suga Y, Nagatomo I, Kinehara Y, Koyama S, Okuzaki D, Osa A, Naito Y, Takamatsu H, Nishide M, Nojima S, Ito D, Tsuda T, Nakatani T, Nakanishi Y, Futami Y, Koba T, Satoh S, Hosono Y, Miyake K, Fukushima K, Shiroyama T, Iwahori K, Hirata H, Takeda Y, Kumanogoh A.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 207 Issue: 5 Pages: 1456-1467
- DOI
  10.4049/jimmunol.2100076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08602, KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-19K08650
[Journal Article] Favorable response to trastuzumab plus irinotecan combination therapy in two patients with HER2-positive relapsed small-cell lung cancer.2015
- Author(s)
  Kinehara Y, Minami T, Kijima T, Hoshino S, Morimura O, Otsuka T, Hayama Y, Fukushima K, Takeuchi Y, Higashiguchi M, Miyake K, Hirata H, Nagatomo I, Inoue K, Takeda Y, Kida H, Kumanogoh A.
- Journal Title
  
  Lung Cancer.
  
  Volume: 87 Issue: 3 Pages: 321-325
- DOI
  10.1016/j.lungcan.2015.01.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591165, KAKENHI-PROJECT-26860606
[Journal Article] Overcoming chemoresistance of small-cell lung cancer through stepwise HER2-targeted antibody-dependent cell-mediated cytotoxicity and VEGF-targeted antiangiogenesis.2013
- Author(s)
  Minami T, Kijima T, Kohmo S, Arase H, Otani Y, Nagatomo I, Takahashi R, Miyake K, Higashiguchi M, Morimura O, Ihara S, Tsujino K, Hirata H, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A.
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 2669-2669
- DOI
  10.1038/srep02669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591165, KAKENHI-PUBLICLY-25133705, KAKENHI-PROJECT-25670143
[Journal Article] HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer.2012
- Author(s)
  Minami T, Kijima T, Otani Y, Kohmo S, Takahashi R, Nagatomo I, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 11(4) Issue: 4 Pages: 830-841
- DOI
  10.1158/1535-7163.mct-11-0884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591165
[Presentation] IL-33は樹状細胞のSema4A発現を増強させ、抗腫瘍効果を示す2021
- Author(s)
  菅泰彦、長友泉、小山正平、内藤祐二朗、福島清春、三宅浩太郎、白山敬之、平田陽彦、岩堀幸太、武田吉人、熊ノ郷淳
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08602
[Presentation] Semaphorin 4A on dendric cells contributes to IL-33 induced antitumor immunity2021
- Author(s)
  Yasuhiko Suga, Izumi Nagatomo, Shohei Koyama, Koutarou Miyake, Atsushi Kumanogoh
- Organizer
  The 27th International Symposium on Molecular Cell Biology of Macrophages
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08602
[Presentation] IL-33は腫瘍環境を修飾し抗腫瘍免疫を高めることで腫瘍増殖を抑える2020
- Author(s)
  菅泰彦、長友泉、小山正平、三宅浩太郎、熊ノ郷淳
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08602
[Presentation] HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer2012
- Author(s)
  南俊行，木島貴志，大谷安司，河面聡，高橋良，長友泉，平田陽彦，鈴木真優美，井上幸治，武田吉人，木田博，立花功，熊ノ郷淳
- Organizer
  第103回　AACR (Ammerican Association for Cancer Research) annual meeting
- Place of Presentation
  米国シカゴ
- Data Source
  KAKENHI-PROJECT-24591165
[Presentation] Molecular targeting therapy to overcome chemoresistance in small cell lung cancer2012
- Author(s)
  南俊行，木島貴志，河面聡，大谷安司，高橋良，長友泉，武田吉人，立花功，熊ノ郷淳
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  北海道札幌
- Data Source
  KAKENHI-PROJECT-24591165
[Presentation] HER2陽性再発小細胞肺癌に対するirinotecan + trastuzumab併用療法（基礎研究から臨床応用まで）
- Author(s)
  南俊行，甲原雄平，木島貴志，森村治、大塚倫之，三宅浩太郎，竹内美子、井上幸治，長友泉，木田博，熊ノ郷淳
- Organizer
  第55回日本肺癌学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-11-14 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24591165
[Presentation] Targeting HER2 and VEGF stepwise can overcome multidrug resistance in small cell lung cancer.
- Author(s)
  Minami T, Kijima T, Kinehara Y, Morimura O, Higashiguchi M, Miyake K, Hirata H, Takeuchi Y, Fukushima K, Hayama Y, Inoue K, Nagatomo I, Takeda Y, Kida H, Kumanogoh A.
- Organizer
  第105回米国癌学会(AACR) 2014
- Place of Presentation
  San Diego、CA, USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24591165

1. OKA Yoshihiro (20273691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. TAKEDA Yoshito (40452388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TAKAHASHI Ryo (10546865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OTSUKA Tomoyuki (20730576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KIJIMA TAKASHI (90372614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. KOHMO Satoshi (40625670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. MINAMI Toshiyuki (00705113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

Nagatomo Izumi 長友 泉

NAGATOMO Izumi 長友 泉

Research Projects

Research Products

Co-Researchers

ミトコンドリア動態を鍵因子とする、細胞老化制御と発癌抑制の両立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutic strategies for EGFR mutation-positive lung cancer by targeting semaphorin 7APrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of WT1 peptide-based immunotherapy for inoperable thoracic malignant tumors, and analysis of immunodynamics of the novel therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HER2 target therapy for multidrug-resistant small cell lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identifying and overcoming mechanisms of ALK tyrosine kinase inhibitor resistance in lung cancer cells bearing EML4-ALK gene fusions.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IL-33 Induces Sema4A Expression in Dendritic Cells and Exerts Antitumor Immunity2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Favorable response to trastuzumab plus irinotecan combination therapy in two patients with HER2-positive relapsed small-cell lung cancer.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overcoming chemoresistance of small-cell lung cancer through stepwise HER2-targeted antibody-dependent cell-mediated cytotoxicity and VEGF-targeted antiangiogenesis.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] IL-33は樹状細胞のSema4A発現を増強させ、抗腫瘍効果を示す2021

Author(s)

Organizer

Data Source

[Presentation] Semaphorin 4A on dendric cells contributes to IL-33 induced antitumor immunity2021

Author(s)

Organizer

Data Source

[Presentation] IL-33は腫瘍環境を修飾し抗腫瘍免疫を高めることで腫瘍増殖を抑える2020

Author(s)

Organizer

Data Source

[Presentation] HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Molecular targeting therapy to overcome chemoresistance in small cell lung cancer2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] HER2陽性再発小細胞肺癌に対するirinotecan + trastuzumab併用療法（基礎研究から臨床応用まで）

Author(s)

Organizer

Nagatomo Izumi 長友泉

NAGATOMO Izumi 長友泉