SHIMADA masaya 島田昌也

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SHIMADA Masaya 島田昌也

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Researcher Number	10576755
Other IDs
Affiliation (Current)	2025: 岐阜大学, 応用生物科学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 岐阜大学, 応用生物科学部, 准教授 2013 – 2014: 岐阜大学, 応用生物科学部, 助教 2010 – 2011: 千葉県立保健医療大学, 健康科学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 08030:Family and consumer sciences, and culture and living-related / Eating habits / Food science Except Principal Investigator Food science
Keywords	Principal Investigator 果糖 / 脂肪酸合成 / アセチル化ヒストン / 単純性脂肪肝 / 肝臓 / ChREBP / フルクトース / 内臓脂肪 / 消化管 / エピゲノム … More / イノシトール / IL-25 / RNAP II / CDK9 / アセチル化ヒストンH3 / 酪酸 / ミオイノシトール / 脂肪肝 / FASN / ヒストンアセチル化 / プロモーター / 脂肪合成系遺伝子 / 糖輸送体 / THRSP / クロマトグラフィー / ミセル / 胆汁酸 / コレステロール / 米糠タンパク質 / 食後高血糖 / 小腸 / GIP / α-グルコシダーゼ / EGCG … More Except Principal Investigator 脂質 / ソイスタチン / カルシウムシグナル / 胆汁酸輸送担体 / ペプチドアレイ / HepG2 / CYP7A1 / ラクトスタチン / 動脈硬化 / 胆汁酸 / ミセル / ペプチド / コレステロール Less

消化管を標的とした低用量果糖摂取による肥満予防作用とエピゲノム変化の解析Principal Investigator
- Principal Investigator
  
  島田昌也
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Gifu University
Research on epigenomic regulation around lipogenic genes in high-fructose-induced fatty liverPrincipal Investigator
- Principal Investigator
  
  Masaya Shimada
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Gifu University
Epigenetic regulation in simple fatty liver induced by dietary factorsPrincipal Investigator
- Principal Investigator
  
  Shimada Masaya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Gifu University
Regulation of absorptive function via THRSP in the small intestine and the development for risk reduction of cardiovascular diseasePrincipal Investigator
- Principal Investigator
  
  SHIMADA Masaya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Gifu University
Discovery of Innovative lipid lowering peptides by targetting the bio-molecule and Creation of novel screening technology
- Principal Investigator
  
  Nagaoka Satoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Gifu University
Cholesterol-Lowering Effect of Novel Bile Acid-Binding Proteins from Rice BranPrincipal Investigator
- Principal Investigator
  
  SHIMADA Masaya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Gifu University
Effect of continuous dietary supplementation with EGCG on suppression of postprandial hyperglycemia via regulation of small intestinal functionPrincipal Investigator
- Principal Investigator
  
  SHIMADA Masaya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Food science
- Research Institution
  Chiba Prefectural University of Health Sciences

All 2023 2022 2021 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Treatment with Interleukin-25 Suppresses Short-Term High-Fructose Diet-Induced Hepatic Gene Expression and Activities of Fatty Acid Synthesis Enzymes in Rats2023
- Author(s)
  Shimada Masaya、Shirouchi Bungo、Kobayashi Yota、Higuchi Mina、Okumura Mai、Nakagawa Tomoyuki、Hayakawa Takashi
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 72 Issue: 1 Pages: 99-104
- DOI
  10.5650/jos.ess22266
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K02073
[Journal Article] Dietary supplementation with sodium butyrate reduces high-sucrose diet-induced hepatic accumulation of triacylglycerols and expression of fatty acid synthesis enzymes in rats2022
- Author(s)
  Hattori Y, Tsutsui S, Yamada C, Kobayashi Y, Nakagawa T, Shimada M
- Journal Title
  
  J Oleo Sci
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K02073
[Journal Article] Effects of H3 and H4 histones acetylation and bindings of CREB binding protein and p300 at the promoter on hepatic expression of γ-glutamyltransferase gene in a streptozotocin-induced moderate hypoinsulinemic rat model2021
- Author(s)
  Tanaka T, Mizuno T, Nakagawa T, Hayakawa T, Shimada M
- Journal Title
  
  Physiol Res
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K02237
[Journal Article] High-fructose diet-induced hepatic expression of the <i>Scd1</i> gene is associated with increased acetylation of histones H3 and H4 and the binding of ChREBP at the <i>Scd1 </i>promoter in rats2021
- Author(s)
  Shimada M, Hibi M, Nakagawa T, Hayakawa T, Field CJ
- Journal Title
  
  Biomed. Res.
  
  Volume: 42 Issue: 2 Pages: 85-88
- DOI
  10.2220/biomedres.42.85
- NAID
  130008023676
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2021-04-10
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K02237
[Journal Article] Dietary supplementation with myo-inositol reduces high-fructose diet-induced hepatic ChREBP binding and acetylation of histones H3 and H4 on the Elovl6 gene in rats2021
- Author(s)
  Hibi M, Nakagawa T, Hayakawa T, Yanase E, Shimada M
- Journal Title
  
  Nutr Res
  
  Volume: 88 Pages: 28-33
- DOI
  10.1016/j.nutres.2020.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K02237
[Journal Article] Effects of Dietary Supplementation with Myo-inositol on Hepatic Expression of Glycolytic and Fructolytic Enzyme Genes in Rats Fed a High-sucrose Diet2021
- Author(s)
  Hibi M, Sugiura S, Nakagawa T, Hayakawa T, Shimada M
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 70 Issue: 5 Pages: 697-702
- DOI
  10.5650/jos.ess20340
- NAID
  130008032833
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K02237
[Journal Article] High-fructose diet-induced hypertriglyceridemia Is associated with enhanced hepatic expression of ACAT2 in rats2019
- Author(s)
  Ichigo Y, Takeshita A, Hibino M, Nakagawa T, Hayakawa T, Patel D, Field CJ, Shimada M
- Journal Title
  
  Physiol Res
  
  Volume: 68 Pages: 1021-1026
- DOI
  10.33549/physiolres.934226
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K02237
[Journal Article] Treatment with myo-inositol attenuates binding of the carbohydrate-responsive element-binding protein to the ChREBP-β and FASN genes in rat nonalcoholic fatty liver induced by high-fructose diet.2019
- Author(s)
  Shimada M, Ichigo Y, Shirouchi B, Takashima S, Inagaki M, Nakagawa T, Hayakawa T
- Journal Title
  
  Nutr Res.
  
  Volume: 64 Pages: 49-55
- DOI
  10.1016/j.nutres.2019.01.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K02237
[Journal Article] Dietary supplementation with myo -inositol reduces hepatic triglyceride accumulation and expression of both fructolytic and lipogenic genes in rats fed a high-fructose diet2017
- Author(s)
  Masaya SHIMADA, Masato HIBINO, Anna TAKESHITA
- Journal Title
  
  Nutrition Research
  
  Volume: 47 Pages: 21-27
- DOI
  10.1016/j.nutres.2017.08.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K16205
[Journal Article] Identification of the active protein in rice bran protein having an inhibitory activity of cholesterol micellar solubility.2017
- Author(s)
  Jilt Wang, Masaya Shimada and Satoshi Nagaoka
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 印刷中 Issue: 6 Pages: 1216-1219
- DOI
  10.1080/09168451.2017.1282811
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292067
[Journal Article] Cholesterol-Lowering Effect of Rice Bran Protein Containing Bile Acid-Binding Proteins2015
- Author(s)
  Jilite Wang, Masaya Shimada, Yukina Kato, Mio Kusada, and Satoshi Nagaoka
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry
  
  Volume: 79 Issue: 3 Pages: 456-461
- DOI
  10.1080/09168451.2014.978260
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25750039
[Presentation] 短期高フルクトース誘導性の脂肪肝モデルの活用2023
- Author(s)
  島田昌也
- Organizer
  日本農芸化学会2023年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K02073
[Presentation] フルクトース誘導性の肝臓脂肪酸合成系を制御する因子に関する研究2022
- Author(s)
  島田昌也
- Organizer
  日本農芸化学会中部支部第192回例会ミニシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K02073
[Presentation] 高脂肪高ショ糖食へのマルトビオン酸補充は肝臓脂肪および内臓脂肪の蓄積を軽減する2022
- Author(s)
  原誠弥, 山田千尋, 末廣大樹, 深見健, 中川智行, 早川享志, 島田昌也
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K02073
[Presentation] マルトビオン酸が高脂肪・高ショ糖食負荷ラットの糖・脂質代謝に及ぼす影響2021
- Author(s)
  山田千尋, 原誠弥, 末廣大樹, 中川智行, 早川享志, 島田昌也
- Organizer
  第79回日本栄養・食糧学会中部支部大会
- Data Source
  KAKENHI-PROJECT-21K02073
[Presentation] ミオイノシトールによる肝臓中性脂肪蓄積の抑制機構に関する研究2018
- Author(s)
  市古雄太郎, 稲垣瑞穂, 中川智行, 早川享志, 島田昌也
- Organizer
  日本農芸化学会中部支部第183回例会
- Data Source
  KAKENHI-PROJECT-18K02237
[Presentation] ラクトスタチン（IIAEK）は肝特異的転写因子HNF-3αを介してコレステロール分解を促進する2017
- Author(s)
  大林由季奈、磯貝渚、井辰かおる、島田昌也、長岡利
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] ペプチドアレイによる新規コレステロール代謝改善ペプチドの探索評価と作用機構解析2016
- Author(s)
  秋江祐希、久松賢太郎、柳瀬笑子、島田昌也、長岡利
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] Identification of the active proteins in rice bran having an inhibitory activity of cholesterol micellar solubility.2016
- Author(s)
  Jilite Wang, Masaya Shimada and Satoshi Nagaoka
- Organizer
  International conference on rice bran oil (2016)
- Place of Presentation
  東京
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] ラクトスタチンの媒介する新規腸コレステロール吸収調節系の解析2015
- Author(s)
  酒井優治、小室あゆ美、山本達記、島田昌也、長岡利
- Organizer
  平成27年度酪農科学シンポジウム
- Place of Presentation
  帯広
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] 大豆由来ペプチドVVFLASVSは疎水性相互作用を介してコレステロールのミセル溶解性を低下させる.2015
- Author(s)
  久松賢太郎, 秋江祐希, 島田昌也, 岩本悟志, 長岡利
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] A novel hypocholesterolemic pentapeptide, lactostatin, inhibits cholesterol absorption via the suppression of ABCA1 gene expression in Caco-2 cells.2015
- Author(s)
  Yuji Sakai, Akemi Komuro, Masaya Shimada, Satoshi Nagaoka
- Organizer
  Asian Congress of Nutrition 2015
- Place of Presentation
  横浜
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] 大豆β-コングリシニン α' サブユニット由来ペプチドのコレステロール代謝改善作用2015
- Author(s)
  山本仁美、金　梨援、島田昌也、長岡　利
- Organizer
  第69回日本栄養・食糧学会中部支部大会
- Place of Presentation
  静岡
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] ラクトスタチンはHNF-3alpha及びカルシウムシグナルを介してコレステロール分解系を活性化する.2015
- Author(s)
  磯貝渚, 古田真優, 島田昌也, 長岡利
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] 米糠タンパク質による新規コレステロール代謝改善食品開発に関する研究2014
- Author(s)
  王吉力特，加藤由喜奈，下田博司，島田昌也，長岡利
- Organizer
  日本農芸化学会中部支部第171回例会
- Place of Presentation
  名古屋
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25750039
[Presentation] IIAEKはHNF-3α及びカルシウムシグナリングを介してコレステロール分解系を活性化する.2014
- Author(s)
  古田真優, 磯貝渚, 井辰かおる, 世古聖士, 島田昌也, 長岡利
- Organizer
  日本アミノ酸学会第8回学術大会
- Place of Presentation
  東京
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PROJECT-26292067
[Presentation] 新規コレステロール吸収抑制ペプチドVVFLASVSのコレステロールミセルに対する影響.2014
- Author(s)
  久松賢太郎, 秋江祐希, 島田昌也, 岩本悟志, 長岡利
- Organizer
  第67回日本栄養・食糧学会中部支部大会
- Place of Presentation
  静岡
- Year and Date
  2014-11-22
- Data Source
  KAKENHI-PROJECT-26292067

1. Nagaoka Satoshi (50202221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
2. 上野義仁 (20250467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 本多裕之 (70209328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 柳瀬笑子 (60313912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 椎名貴彦 (90362178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMADA masaya 島田 昌也

SHIMADA Masaya 島田 昌也

Research Projects

Research Products

Co-Researchers

消化管を標的とした低用量果糖摂取による肥満予防作用とエピゲノム変化の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on epigenomic regulation around lipogenic genes in high-fructose-induced fatty liverPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenetic regulation in simple fatty liver induced by dietary factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of absorptive function via THRSP in the small intestine and the development for risk reduction of cardiovascular diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discovery of Innovative lipid lowering peptides by targetting the bio-molecule and Creation of novel screening technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cholesterol-Lowering Effect of Novel Bile Acid-Binding Proteins from Rice BranPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of continuous dietary supplementation with EGCG on suppression of postprandial hyperglycemia via regulation of small intestinal functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Treatment with Interleukin-25 Suppresses Short-Term High-Fructose Diet-Induced Hepatic Gene Expression and Activities of Fatty Acid Synthesis Enzymes in Rats2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Dietary supplementation with sodium butyrate reduces high-sucrose diet-induced hepatic accumulation of triacylglycerols and expression of fatty acid synthesis enzymes in rats2022

Author(s)

Journal Title

Data Source

[Journal Article] Effects of H3 and H4 histones acetylation and bindings of CREB binding protein and p300 at the promoter on hepatic expression of γ-glutamyltransferase gene in a streptozotocin-induced moderate hypoinsulinemic rat model2021

Author(s)

Journal Title

Data Source

[Journal Article] High-fructose diet-induced hepatic expression of the <i>Scd1</i> gene is associated with increased acetylation of histones H3 and H4 and the binding of ChREBP at the <i>Scd1 </i>promoter in rats2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Dietary supplementation with myo-inositol reduces high-fructose diet-induced hepatic ChREBP binding and acetylation of histones H3 and H4 on the Elovl6 gene in rats2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Dietary Supplementation with Myo-inositol on Hepatic Expression of Glycolytic and Fructolytic Enzyme Genes in Rats Fed a High-sucrose Diet2021

Author(s)

Journal Title

DOI

SHIMADA masaya 島田昌也

SHIMADA Masaya 島田昌也

[Presentation] 高脂肪高ショ糖食へのマルトビオン酸補充は肝臓脂肪および内臓脂肪の蓄積を軽減する2022

[Presentation] マルトビオン酸が高脂肪・高ショ糖食負荷ラットの糖・脂質代謝に及ぼす影響2021

[Presentation] ラクトスタチン（IIAEK）は肝特異的転写因子HNF-3αを介してコレステロール分解を促進する2017