ARAKI YASUTO 荒木靖人

… Alternative Names

Araki Yasuto 荒木靖人

ARAKI Yasuto 荒木靖人

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Researcher Number	10580839
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 埼玉医科大学, 医学部, 准教授 2019 – 2022: 埼玉医科大学, 医学部, 准教授 2015 – 2018: 埼玉医科大学, 医学部, 講師 2010 – 2013: 埼玉医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Immunology / Collagenous pathology/Allergology / Orthopaedic surgery Except Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator エピジェネティクス / 関節リウマチ / ヒストンメチル化 / リウマチ学 / エピゲノム / 転写因子 / クロマチン / T細胞 / 滑膜細胞 / 滑膜線維芽細胞 … More / 関節炎 / MMP分子 / IL-6 / ヒストン修飾 / MMP / 変形性関節症 / 免疫学 / T細胞分化 / CD8陽性T細胞 / リンパ球 / 転写制御 … More Except Principal Investigator 遺伝子発現 / 内科 / エピジェネティクス / リウマチ学 Less

関節リウマチにおけるH3K36メチル化の異常解明および治療標的としての確立Principal Investigator
- Principal Investigator
  
  荒木靖人
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Saitama Medical University
Functiona abnormality and therapeutic possibility of histone methyltransferases in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  ARAKI Yasuto
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Saitama Medical University
Aberrant gene transcription based on chromatin structure in rheumatoid arthritis synovial fibroblastsPrincipal Investigator
- Principal Investigator
  
  Araki Yasuto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Saitama Medical University
The mechanisms of arthritic diseases-specific cartilage destruction by MMP moleculesPrincipal Investigator
- Principal Investigator
  
  Araki Yasuto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
he role of histone modifications in the function and differentiaition of CD8 T cellsPrincipal Investigator
- Principal Investigator
  
  ARAKI Yasuto
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Saitama Medical University
pathogenic changes in histone modification and DNA methylation in synovial fibroblasts from RA joints
- Principal Investigator
  
  MIMURA Toshihide
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saitama Medical University
CD8陽性T細胞におけるヒストンメチル化の制御ネットワークの解明Principal Investigator
- Principal Investigator
  
  荒木靖人
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Saitama Medical University

All 2023 2022 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] Epigenetics in Human Disease, 2nd edition2018
- Author(s)
  Araki Y, Mimura T
- Total Pages
  34
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-16K09903
[Book] 臨床病態学2巻2013
- Author(s)
  荒木靖人, 他
- Publisher
  ヌーヴェルヒロカワ社
- Data Source
  KAKENHI-PROJECT-23790544
[Book] 南山堂医学大辞典
- Author(s)
  荒木靖人, 他
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-23790544
[Journal Article] Induction of memory-like CD8+ T cells and CD4+ T cells from human naive T cells in culture2022
- Author(s)
  Yasuhito Tokumoto, Yasuto Araki, Yusuke Narizuka, Yosuke Mizuno, Susumu Ohshima, Toshihide Mimura
- Journal Title
  
  Clinical and Experimental Immunology
  
  Volume: 207 Issue: 1 Pages: 95-103
- DOI
  10.1093/cei/uxab012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08888, KAKENHI-PROJECT-21K07326
[Journal Article] 関節リウマチの血液検査2019
- Author(s)
  荒木靖人
- Journal Title
  
  SSCさくらそう（公益社団法人日本リウマチ友の会埼玉支部会誌）
  
  Volume: 132 Pages: 9-15
- Data Source
  KAKENHI-PROJECT-19K08888
[Journal Article] Aberrant gene expression of histone lysine methyltransferases and demethylases in rheumatoid arthritis synovial fibroblasts2018
- Author(s)
  Araki Y, Aizaki Y, Sato K, Oda H, Kurokawa R, Mimura T
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 36 Pages: 314-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09903
[Journal Article] Matrix metalloproteinase gene activation resulting from disordered epigenetic mechanisms in rheumatoid arthritis2017
- Author(s)
  Araki Y, Mimura T
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 5 Pages: 905-905
- DOI
  10.3390/ijms18050905
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09903, KAKENHI-PROJECT-16K09902
[Journal Article] 関節リウマチ滑膜におけるヒストンメチル化とIL-6誘導によるMMP遺伝子2017
- Author(s)
  荒木靖人
- Journal Title
  
  Keynote R・A
  
  Volume: 5 Pages: 14-18
- Data Source
  KAKENHI-PROJECT-16K09903
[Journal Article] The histone modification code in the pathogenesis of autoimmune diseases2017
- Author(s)
  Araki Y, Mimura T
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2017 Pages: 2608605-2608605
- DOI
  10.1155/2017/2608605
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09902, KAKENHI-PROJECT-16K09903
[Journal Article] Histone Methylation and STAT-3 Differentially Regulate Interleukin-6-Induced Matrix Metalloproteinase Gene Activation in Rheumatoid Arthritis Synovial Fibroblasts.2016
- Author(s)
  Araki Y, Tsuzuki Wada T, Aizaki Y, Sato K, Yokota K, Fujimoto K, Kim YT, Oda H, Kurokawa R, Mimura
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 68 Issue: 5 Pages: 1111-23
- DOI
  10.1002/art.39563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10488, KAKENHI-PROJECT-25461482, KAKENHI-PROJECT-25462379, KAKENHI-PROJECT-25293073, KAKENHI-PROJECT-16K09902, KAKENHI-PROJECT-16K09903
[Journal Article] The mechanisms underlying chronic inflammation in rheumatoid arthritis from the perspective of the epigenetic landscape2016
- Author(s)
  Araki Y, Mimura T
- Journal Title
  
  Journal of Immunology Research
  
  Volume: 2016 Pages: 6290682-6290682
- DOI
  10.1155/2016/6290682
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09902, KAKENHI-PROJECT-16K09903
[Journal Article] Aberrant histone acetylation contributes to elevated interleukin-6 production in rheumatoid arthritis synovial fibroblasts2014
- Author(s)
  Wada TT, Araki Y, Sato K, Aizaki Y, Yokota K, Kim YT, Oda H, Kurokawa R, Mimura T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 444 Issue: 4 Pages: 682-686
- DOI
  10.1016/j.bbrc.2014.01.195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591467, KAKENHI-PROJECT-25293073, KAKENHI-PROJECT-25461482, KAKENHI-PROJECT-25462379
[Journal Article] Combination of tumor necrosis factor α and interleukin-6 induces mouse osteoclast-like cells with bone resorption activity both in vitro and in vivo2014
- Author(s)
  Yokota K, Sato K, Miyazaki T, Kitaura H, Kayama H, Miyoshi F, Araki Y, Akiyama Y, Takeda K, Mimura T.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 66 Issue: 1 Pages: 121-129
- DOI
  10.1002/art.38218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591467, KAKENHI-PROJECT-24593075, KAKENHI-PROJECT-25461482, KAKENHI-PROJECT-25462379
[Journal Article] Implicated role of liposarcoma related fusion oncoprotein TLS-CHOP in the dysregulaiton of arginine-specific methylation through PRMT12013
- Author(s)
  Kenta Fujimoto, Shigeki Arai, Maki Matsubara, Kun Du, Yasuto Araki, Akio Matsushita, Riki Kurokawa
- Journal Title
  
  Cell Biology
  
  Volume: Vol.1、No.2 Issue: 2 Pages: 18-23
- DOI
  10.11648/j.cb.20130102.11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24810023, KAKENHI-PROJECT-25462379
[Journal Article] The molecular basis of the memory T cell response: differential gene expression and its epigenetic regulation.2012
- Author(s)
  Weng NP, Araki Y, Subedi K
- Journal Title
  
  Nature Reviews Immunology
  
  Volume: 12(4) Pages: 306-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790544
[Journal Article] The chromatin basis of memory T cell response: differential gene expression and its epigenetic regulation2012
- Author(s)
  Weng NP, Araki Y, Subedi K
- Journal Title
  
  Nat rev Immunol
  
  Volume: 12 Issue: 4 Pages: 306-315
- DOI
  10.1038/nri3173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790544
[Journal Article] 関節リウマチにおけるエピジェネティクス制御の異常の解明2012
- Author(s)
  荒木靖人
- Journal Title
  
  埼玉医科大学雑誌
  
  Volume: 39 Pages: 4-8
- Data Source
  KAKENHI-PROJECT-23790544
[Journal Article] Marked induction of c-Maf protein during Th17 cell differentiation and its implication in memory Th cell development2011
- Author(s)
  Sato K, Miyoshi F, Yokota K, Araki Y, Asanuma Y, Akiyama Y, Yoh K, Takahashi S, Aburatani H, Mimura T
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 17 Pages: 14963-14971
- DOI
  10.1074/jbc.m111.218867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591083, KAKENHI-PROJECT-23591467, KAKENHI-PROJECT-23790544
[Journal Article] Marked Induction of c-Maf Protein during Th17 Cell Differentiation and Its Implication in Memory Th Cell Development2011
- Author(s)
  佐藤浩二郎、三由文彦、横田和浩、荒木靖人, 他6名
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: VOL.286 Pages: 14963-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890172
[Journal Article] Marked induction of c-Maf protein during Th17 cell differentiation and its implication in memory Th cell development.2011
- Author(s)
  Sato K, Miyoshi F, Yokota K, Araki Y, Asanuma Y, Akiyama Y, Yoh K, Takahashi S, Aburatani H, Mimura T
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286(17) Pages: 14963-14971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790544
[Journal Article] CD8陽性T細胞の分化・機能におけるヒストン修飾の役割：ゲノムワイドな解析を含めた最新の知見2011
- Author(s)
  荒木靖人
- Journal Title
  
  日本臨床免疫学会誌
  
  Volume: 34(3) Pages: 131-137
- NAID
  10029432054
- Data Source
  KAKENHI-PROJECT-23790544
[Journal Article] CD8 陽性 T 細胞の分化・機能におけるヒストン修飾の役割:ゲノムワイドな解析を含めた最新の知見2011
- Author(s)
  荒木靖人
- Journal Title
  
  日本臨床免疫学会誌
  
  Volume: 34(3) Pages: 131-137
- NAID
  10029432054
- Data Source
  KAKENHI-PROJECT-23790544
[Journal Article] 関節リウマチ患者罹患関節における熱ショック蛋白96とToll-like receptor2010
- Author(s)
  荒木靖人
- Journal Title
  
  月刊リウマチ科
  
  Volume: VOL.43 Pages: 407-413
- Data Source
  KAKENHI-PROJECT-22890172
[Presentation] 関節リウマチ滑膜線維芽細胞における転写因子 SOX11 によるサイトカインとケモカイン遺伝子発現の制御異常2023
- Author(s)
  荒木靖人、岡元啓太、相崎良美、横田和浩、梶山浩、舟久保ゆう、秋山雄次、門野夕峰、三村俊英
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] SLE患者におけるヒドロキシクロロキン内服と3年間の腎機能変化との関連　-LUNAレジストリを用いたコホート観察研究2022
- Author(s)
  梶山浩，矢島宣幸，宮脇義亜，一瀬邦弘，吉見竜介，大野滋，佐藤秀三，下島恭弘，藤原道雄，佐田憲映，大西輝，木田節，松尾祐介，江本恭平，酒井左近，岡元啓太，松田真弓，矢澤宏晃，柳澤麻依子，丸山崇，和田琢，吉田佳弘，横田和浩，荒木靖人，舟久保ゆう，秋山雄次，三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] SARS-CoV-2ワクチン接種後に成人発症スチル病を新規発症した３例2022
- Author(s)
  松田真弓，舟久保ゆう，江本恭平，岡元啓太，矢澤宏晃，和田琢，横田和浩，梶山浩，荒木靖人，三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] 炎症性筋疾患との鑑別が困難であった遠位型ミオパチーの１例2022
- Author(s)
  江本恭平，横田和浩，酒井左近，岡元啓太，松田真弓，矢澤宏晃，丸山崇，和田琢，吉田佳弘，梶山浩，荒木靖人，舟久保ゆう，三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] 生物学的製剤治療歴のある関節リウマチ症例へのサリルマブの有効性の検討2022
- Author(s)
  吉田佳弘，矢澤宏晃，横田和浩，梶山浩，荒木靖人，舟久保ゆう，秋山雄次，三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] ＷＤＲ5阻害薬における関節リウマチ滑膜線維芽細胞におけるケモカインの発現抑制2022
- Author(s)
  岡元啓太，荒木靖人，相崎良美，門野夕峰，舟久保ゆう，三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] 当科における関節リウマチに対するアバタセプト（ABT）とゴリムマブ（GLM）の治療成績（416週）の比較検討2022
- Author(s)
  秋山雄次，和田琢，高松真裕子，柳澤麻依子，丸山崇，吉田佳弘，横田和浩，神津教倫，梶山浩，荒木靖人，舟久保ゆう，三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] 乾癬性関節炎が不安，抑うつに及ぼす影響ついての検討2022
- Author(s)
  和田琢，舟久保ゆう，菅野温子，伊澤直広，吉田佳弘，横田和浩，梶山浩，荒木靖人，門野夕峰，三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] WDR5 阻害剤による関節リウマチ滑膜線維芽細胞におけるケモカインの発現抑制2022
- Author(s)
  岡元啓太、荒木靖人、相崎良美、門野夕峰、舟久保ゆう、三村俊英
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] Functional differences between osteoblasts and osteoclast-like cells differentiated from peripheral blood mononuclear cells in patients with rheumatoid arthritis2019
- Author(s)
  Kazuhiro Yokota, Yoshimi Aizaki, Shinya Tanaka, Kojiro Sato, Yasuto Araki, Noritsune Kouzu, Yuho Kadono, Hiromi Oda, Toshihide Mimura
- Organizer
  American College of Rheumatology, the Annual Scientific Meeting 2019, Atlanta
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] Histone methyltransferase MLL1 regulates the expression of cytokines and chemokines in rheumatoid arthritis synovial fibroblasts2019
- Author(s)
  Yasuto Araki, Keita Okamoto, Yoshimi Aizaki, Hiromi Oda, Toshihide Mimura
- Organizer
  American College of Rheumatology, the Annual Scientific Meeting 2019, Atlanta
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] Aberration of histone lysine methylation in Adult-onset Still's disease are novel biomarker candidates associated with the disease activity2019
- Author(s)
  Yoshimi Aizaki, Yasuto Araki, Kojiro Sato, Toshihide Mimura
- Organizer
  American College of Rheumatology, the Annual Scientific Meeting 2019, Atlanta
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08888
[Presentation] 関節リウマチ滑膜線維芽細胞におけるヒストンH3リシン4メチル基転移酵素によるケモカイン遺伝子転写制御の異常2017
- Author(s)
  荒木靖人、相崎良美、横田和浩、梶山浩、舟久保ゆう、佐藤浩二郎、織田弘美、三村俊英
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2017-04-20
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] Histone lysine methylation and STAT3 differentially regulate constitutive and IL-6-induced MMP gene activation in rheumatoid arthritis synovial fibroblasts2017
- Author(s)
  Araki Y, Mimura T
- Organizer
  Keystone symposia, Epigenetics and human disease: progress from mechanisms to therapeutics
- Place of Presentation
  Sheraton Seattle Hotel, Seattle, USA
- Year and Date
  2017-01-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] 関節リウマチ滑膜線維芽細胞におけるH3K4ヒストンメチル基転移酵素によるケモカイン遺伝子活性化の機構2017
- Author(s)
  荒木靖人、和田琢、相崎良美、油谷浩幸、三村俊英
- Organizer
  第11回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] Histone lysine methylation and STAT3 differentially regulate constitutive and IL-6-induced MMPs gene activation in rheumatoid arthritis synovial fibroblasts2016
- Author(s)
  Y. Araki, TT. Wada, Y. Aizaki, K. Sato T. Mimura
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター・ラグナガーデンホテル（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] Altered profiles of histone lysine methylation affect MMP gene transcription in rheumatoid arthritis synovial fibroblasts2016
- Author(s)
  Araki Y, Wada TT, Aizaki Y, Kajiyama H, Yokota K, Sato K, Asanuma YF, Kim YT, Oda H, Mimura T
- Organizer
  Annual European Congress of Rheumatology EULAR 2016
- Place of Presentation
  ExCel London, London, UK
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] Histone methylation in γδ T cells as a biomarker of Behcet’s disease activity2016
- Author(s)
  Aizaki Y, Araki Y, Sato K, Yokota K, Mimura T
- Organizer
  American College of Rheumatology, the Annual Scientific Meeting 2016
- Place of Presentation
  Washington DC Convention Center, Washington DC, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] Altered profiles of histone lysine methylation affect MMP gene transcription in rheumatoid arthritis synovial fibroblasts2016
- Author(s)
  Araki Y, Wada TT, Aizaki Y, Kajiyama H, Yokota K, Sato K, Asanuma YF, Kim YT, Oda H, Mimura T
- Organizer
  Annual European Congress of Rheumatology EULAR 2016
- Place of Presentation
  ExCel London, UK
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] 関節リウマチ滑膜線維芽細胞におけるヒストンメチル化とSTAT3によるIL-6誘導性MMP遺伝子活性化2016
- Author(s)
  荒木靖人、和田琢、相崎良美、佐藤浩二郎、織田弘美、三村俊英
- Organizer
  第2回日本骨免疫学会
- Place of Presentation
  ホテルモントレ沖縄スパ＆リゾート（沖縄県国頭郡）
- Year and Date
  2016-07-06
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] The epigenetic mechanism of constitutive and IL-6-induced MMP gene activation in rheumatoid arthritis synovial fibroblasts2016
- Author(s)
  Yasuto Araki, Takuma Tsuzuki Wada, Yoshimi Aizaki, Hiroshi Kajiyama, Kazuhiro Yokota, Kojiro Sato, Yu Funakubo Asanuma, Yoon-Taek Kim, Hiromi Oda, Toshihide Mimura
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] The epigenetic mechanism of constitutive and IL-6-induced MMP gene activation in rheumatoid arthritis synovial fibroblasts2016
- Author(s)
  Yasuto Araki, Takuma Tsuzuki Wada, Yoshimi Aizaki, Hiroshi Kajiyama, Kazuhiro Yokota, Kojiro Sato, Yu Funakubo Asanuma, Yoon-Taek Kim, Hiromi Oda, Toshihide Mimura
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] Histone lysine methylation and STAT3 differentially regulate constitutive and IL-6-induced MMPs gene activation in rheumatoid arthritis synovial fibroblasts2016
- Author(s)
  Araki Y, Wada TT, Aizaki Y, Yokota K, Kajiyama H, Asanuma YF, Sato K, Oda H, Mimura T
- Organizer
  American College of Rheumatology, the Annual Scientific Meeting 2016
- Place of Presentation
  Washington DC Convention Center, Washington DC, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09903
[Presentation] 関節リウマチ滑膜線維芽細胞におけるヒストン3リシン4メチル基転移酵素の異常2015
- Author(s)
  荒木靖人、和田琢、相崎良美、横田和浩、梶山浩、秋葉春彦、佐藤浩二郎、秋山雄次、金潤澤、織田弘美、三村俊英
- Organizer
  第59回日本リウマチ学会総会・学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] 関節リウマチ滑膜線維芽細胞におけるH3K4ヒストンメチル基転移酵素によるケモカイン遺伝子発現の制御2015
- Author(s)
  荒木靖人、和田琢、相崎良美、佐藤浩二郎、黒川理樹、三村俊英
- Organizer
  第9回日本エピジェネティクス研究会年会
- Place of Presentation
  東京一ツ橋学術総合センター（東京都千代田区）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] 関節リウマチ滑膜線維芽細胞の IL-6 依存性 MMP 遺伝子転写活性化におけるヒストンメチル化の役割2013
- Author(s)
  荒木靖人、和田琢、佐藤浩二郎、横田和浩、三由文彦、梶山浩、舟久保ゆう、金潤澤、織田弘美、秋山雄次、三村俊英
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都国際会議場
- Year and Date
  2013-04-18
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] 関節リウマチ滑膜線維芽細胞のIL-6依存性MMP遺伝子転写活性化におけるヒストンメチル化の役割2013
- Author(s)
  荒木靖人、和田琢、佐藤浩二郎、織田弘美、黒川理樹、三村俊英
- Organizer
  第7回日本エピジェネティクス研究会年会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] 関節リウマチ滑膜線維芽細胞の IL-6 依存性 MMP 遺伝子転写活性化におけるヒストンメチル化の役割2013
- Author(s)
  荒木靖人、和田琢、佐藤浩二郎、織田弘美、黒川理樹、三村俊英
- Organizer
  第7回日本エピジェネティクス研究会年会
- Place of Presentation
  奈良新公会堂
- Year and Date
  2013-05-30
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] Histone methylation is associated with MMPs gene transcriptional activation in rheumatoid arthritis synovial fibroblasts.2012
- Author(s)
  Y. Araki, T. Wada, K. Sato, N. Kurosawa, K. Fujimoto, S. Suzuki, K. Yokota, F. Miyoshi, YT. Kim, H. Oda, R. Kurokawa, T. Mimura
- Organizer
  The 10th RCGM International Symposium of Academic
- Place of Presentation
  Commemoration Hall, Saitama Medcal University Hidaka Campus, Saitama, Japan
- Year and Date
  2012-11-03
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] Histone methylation is associated with MMP gene expressions in rheumatoid arthritis synovial fibroblasts.2011
- Author(s)
  Araki Y, Yokota K, Sato K, Miyoshi F, Wada T, Kim YT, Oda H, Mimura T
- Organizer
  The 4th East Asian Group of Rheumatology (EAGOR2011)
- Place of Presentation
  Keio Plaza Hotel Tokyo, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] 関節リウマチの滑膜線維芽細胞におけるヒストンメチル化は MMPs 遺伝子発現と関連する2011
- Author(s)
  荒木靖人
- Organizer
  第55回日本リウマチ学会総会・学術集会・第20回国際リウマチシンポジウム
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-22591083
[Presentation] Dynamic changes of gene expression in concordance with histone modifications in CD8 T cells after activation2011
- Author(s)
  Subedi K, Araki Y, De S, Wood W, Sharov A, Zang C, Schones D, Lhotsky B, Dudekula D, Becker K, Ko M, Peng W, Zhao K, Weng NP
- Organizer
  98th The American Association of Immunologists Annual Meeting
- Place of Presentation
  the Moscone Center, San Francisco, California, USA.
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] 関節リウマチの滑膜線維芽細胞におけるヒストンメチル化はMMPs遺伝子発現と関連する2011
- Author(s)
  荒木靖人、横田和浩、三由文彦、佐藤浩二郎、金潤澤、織田弘美、三村俊英
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸ポートピアホテル, 神戸
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] Histone methylation is associated with MMP gene expressions in rheumatoid arthritis synovial fibroblasts2011
- Author(s)
  荒木靖人
- Organizer
  The 4th East Asian Group of Rheumatology -EAGOR2011
- Place of Presentation
  京王プラザ(東京都)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22591083
[Presentation] Histone methylation is associated with MMP gene expressions in rheumatoid arthritis synovial fibroblasts2011
- Author(s)
  Araki Y, Yokota K, Sato K, Miyoshi F, Wada T, Kim YT, Oda H, Mimura T.
- Organizer
  The 4th East Asian.Group of Rheumatology (EAGOR2011)
- Place of Presentation
  Keio Plaza Hotel Tokyo, Tokyo, Japan
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] Histone methylation is associated with MMP gene expressions in rheumatoid arthritis synovial fibroblasts2011
- Author(s)
  荒木靖人
- Organizer
  The 4th East Asian Group of Rheumatology-EAGOR2011
- Place of Presentation
  東京(京王プラザ)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22591083
[Presentation] 関節リウマチの滑膜線維芽細胞におけるヒストンメチル化は MMPs 遺伝子発現と関連する2011
- Author(s)
  荒木靖人、横田和浩、三由文彦、佐藤浩二郎、金潤澤、織田弘美、三村俊英
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸ポートピアホテル, 神戸
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] Dynamic changes of gene expression in concordance with histone modifications in CD8 T cells after activation.2011
- Author(s)
  Subedi K, Araki Y, De S, Wood W, Sharov A, Zang C, Schones D, Lhotsky B, Dudekula D, Becker K, Ko M, Peng W, Zhao K, Weng NP
- Organizer
  98th The American Association of Immunologists Annual Meeting
- Place of Presentation
  the Moscone Center, San Francisco, California
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] 関節リウマチの滑膜線維芽細胞におけるヒストンメチル化はMMPs遺伝子発現と関連する2011
- Author(s)
  荒木靖人
- Organizer
  第55回日本リウマチ学会総会・学術集会第20回国際リウマチシンポジウム
- Place of Presentation
  兵庫(神戸国際会議場)
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-22591083
[Presentation] メモリーCD8T細胞における遺伝子発現に対するヒストン修飾の役割2010
- Author(s)
  荒木靖人
- Organizer
  第54回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22591083
[Presentation] メモリーCD8T 細胞における遺伝子発現に対するヒストン修飾の役割2010
- Author(s)
  荒木靖人
- Organizer
  第54回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22591083
[Presentation] メモリーCD8 T細胞における遺伝子発現に対するヒストン修飾の役割2010
- Author(s)
  荒木靖人
- Organizer
  日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22890172
[Presentation] Altered histone methylation is associated with IL-6 dependent matrix metalloproteinases gene transcriptional activation in rheumatoid arthritis synovial fibroblasts
- Author(s)
  Araki Y, Wada TT, Sato K, Yokota K, Miyoshi F, Asanuma YF, Akiyama Y, Mimura T
- Organizer
  American College of Rheumatology, the Annual Scientific Meeting 2013
- Place of Presentation
  San Diego Convention Center, USA
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] 関節リウマチ滑膜線維芽細胞のIL-6依存性MMP遺伝子転写活性化におけるヒストンメチル化の役割
- Author(s)
  荒木靖人、和田琢、佐藤浩二郎、横田和浩、三由文彦、梶山浩、舟久保ゆう、金潤澤、織田弘美、秋山雄次、三村俊英
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] 関節リウマチ滑膜線維芽細胞におけるヒストンメチル化によるIL-6誘導性MMP遺伝子転写活性化の制御機構
- Author(s)
  荒木靖人、和田琢、黒澤奈津子、相崎良美、藤本健太、佐藤浩二郎、横田和浩、三由文彦、金潤澤、織田弘美、黒川理樹、三村俊英
- Organizer
  第11回RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学日高キャンパス　創立30周年記念講堂
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] 関節リウマチ滑膜線維芽細胞のIL-6依存性MMP遺伝子転写活性化におけるヒストンメチル化の役割
- Author(s)
  荒木靖人、和田琢、佐藤浩二郎、横田和浩、三由文彦、梶山浩、舟久保ゆう、金潤澤、織田弘美、秋山雄次、三村俊英
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] 関節リウマチ滑膜線維芽細胞のIL-6依存性MMP遺伝子転写活性化におけるヒストンメチル化の役割
- Author(s)
  荒木靖人、和田琢、佐藤浩二郎、織田弘美、黒川理樹、三村俊英
- Organizer
  第7回日本エピジェネティクス研究会年会
- Place of Presentation
  奈良新公会堂
- Data Source
  KAKENHI-PROJECT-25462379
[Presentation] Histone methylation is associated with MMPs gene transcriptional activation in rheumatoid arthritis synovial fibroblasts
- Author(s)
  Y. Araki, T. Wada, K. Sato, N. Kurosawa, K. Fujimoto, S. Suzuki, K. Yokota, F. Miyoshi, YT. Kim, H. Oda, R. Kurokawa, T. Mimura
- Organizer
  The 10th RCGM International Symposium of Academic
- Place of Presentation
  Commemoration Hall, Saitama Medcal University Hidaka Campus, Saitama, Japan
- Data Source
  KAKENHI-PROJECT-23790544
[Presentation] 関節リウマチ滑膜線維芽細胞のIL-6依存性MMP遺伝子転写活性化におけるヒストンメチル化の役割
- Author(s)
  荒木靖人、和田琢、藤本健太、黒川理樹、三村俊英
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアアイランド
- Data Source
  KAKENHI-PROJECT-25462379

1. MIMURA Toshihide (30260491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. AIZAKI Yoshimi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. FUJIMOTO Kenta

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 佐藤浩二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

ARAKI YASUTO 荒木 靖人

Araki Yasuto 荒木 靖人

ARAKI Yasuto 荒木 靖人

Research Projects

Research Products

Co-Researchers

関節リウマチにおけるH3K36メチル化の異常解明および治療標的としての確立Principal Investigator

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Functiona abnormality and therapeutic possibility of histone methyltransferases in rheumatoid arthritisPrincipal Investigator

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Aberrant gene transcription based on chromatin structure in rheumatoid arthritis synovial fibroblastsPrincipal Investigator

Principal Investigator

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The mechanisms of arthritic diseases-specific cartilage destruction by MMP moleculesPrincipal Investigator

Principal Investigator

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he role of histone modifications in the function and differentiaition of CD8 T cellsPrincipal Investigator

Principal Investigator

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pathogenic changes in histone modification and DNA methylation in synovial fibroblasts from RA joints

Principal Investigator

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CD8陽性T細胞におけるヒストンメチル化の制御ネットワークの解明Principal Investigator

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[Book] Epigenetics in Human Disease, 2nd edition2018

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[Book] 臨床病態学2巻2013

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[Book] 南山堂医学大辞典

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[Journal Article] Induction of memory-like CD8+ T cells and CD4+ T cells from human naive T cells in culture2022

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[Journal Article] 関節リウマチの血液検査2019

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[Journal Article] Aberrant gene expression of histone lysine methyltransferases and demethylases in rheumatoid arthritis synovial fibroblasts2018

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[Journal Article] Matrix metalloproteinase gene activation resulting from disordered epigenetic mechanisms in rheumatoid arthritis2017

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[Journal Article] 関節リウマチ滑膜におけるヒストンメチル化とIL-6誘導によるMMP遺伝子2017

ARAKI YASUTO 荒木靖人

Araki Yasuto 荒木靖人

ARAKI Yasuto 荒木靖人