Okumura Naoki 奥村直毅

… Alternative Names

OKUMURA Naoki 奥村直毅

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Researcher Number	10581499
Other IDs
Affiliation (Current)	2025: 同志社大学, 生命医科学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 同志社大学, 生命医科学部, 教授 2015 – 2018: 同志社大学, 生命医科学部, 准教授 2014: 同志社大学, 公私立大学の部局等, 助教 2011 – 2014: 同志社大学, 生命医科学部, 助教 2011 – 2012: 同志社大学, 公私立大学の部局等, 助教 … More 2011: Kyoto Prefectural University of Medicine, 医学部附属病院, 研究員 2010: 京都府立医科大学, 医学部・附属病院, 専攻医 2010: 京都府立医科大学, 眼科, 病院助教 Less
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related Except Principal Investigator Ophthalmology
Keywords	Principal Investigator 角膜内皮 / フックス角膜内皮ジストロフィ / アポトーシス / Rhoキナーゼ阻害剤 / 角膜 / TCF4 / 角膜移植 / 角膜内皮細胞 / スプライシング / トリプレットリピート … More / MALDI-TOF MS / ショットガン解析 / MALDI-IMS / MALDI / トリプレットリピート病 / 小胞体ストレス / ROCK阻害剤 / Rhoキナーゼ / 上皮間葉移行 … More Except Principal Investigator 再生医療 / SASP / 角膜内皮細胞 / 角膜 / インテグリン / 細胞外マトリクス / p38MAPキナーゼ阻害剤 / 炎症性サイトカイン / ラミニン / p38 MAPキナーゼ / 細胞老化 / メタボローム / 細胞外微粒子 / 細胞相転移 / ヒト角膜内皮細胞 / 眼細胞生物学 / フックス角膜内皮ジストロフィー / フックス角膜ジストロフィー / CD44 / miRNA / エキソゾーム / アスパラギン酸 / アラニン / グルタミン / グルタミン酸 / アルギニン / ヒト角膜上皮細胞 / 涙液 / タイトジャンクション / 上皮細胞 / アミノ酸 / 組織保存 / 細胞移植 / アルジネート / 角膜再生医療 Less

フックス角膜内皮ジストロフィの病態におけるスプライシング異常の意義の解明Principal Investigator
- Principal Investigator
  
  奥村直毅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Doshisha University
Protein Expression Analysis in Patients with Fuchs' Endothelial Corneal Dystrophy Using MALDIPrincipal Investigator
- Principal Investigator
  
  Okumura Naoki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Doshisha University
Effect of CTG triplet repeat expansion in TCF4 on the pathophysiology of Fuchs endothelial corneal dystrophyPrincipal Investigator
- Principal Investigator
  
  Okumura Naoki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Doshisha University
The effect of TGC triplet repeat expansion on the pathophysiology of Fuchs endothelial corneal dystrophyPrincipal Investigator
- Principal Investigator
  
  Okumura Naoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Doshisha University
Paracrine interactions among human cultured corneal endothlial cells regulated the ce state transition in a paracrine fashion
- Principal Investigator
  
  Kinoshita Shigeru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of molecular mechanism of cellular-senescence of corneal endothelial cells in association with cell-culture and its application for corneal endothelial tissue engineering
- Principal Investigator
  
  Koizumi Noriko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Doshisha University
Development of Rho kinase inhibitor eye drop as the therapy for treating corneal endothelial dysfunctionPrincipal Investigator
- Principal Investigator
  
  OKUMURA Naoki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Doshisha University
The effects of the amino acid profile in tear fluid on ocular surface homeostasis and disease condition
- Principal Investigator
  
  SOTOZONO Chie
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Development of new therapy for corneal endothelial dysfunction by modulating epithelial-mesenchymal transitionPrincipal Investigator
- Principal Investigator
  
  OKUMURA Naoki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Doshisha University
角膜内皮のアポトーシス、細胞死の制御による水疱性角膜症に対する新規治療法の開発Principal Investigator
- Principal Investigator
  
  奥村直毅
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Corneal Tissue Engineering Using Alginate
- Principal Investigator
  
  KOIZUMI Noriko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Doshisha University

All 2023 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 医学のあゆみ2023
- Author(s)
  奥村直毅
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-21K09731
[Book] 【眼科臨床エキスパート】角結膜疾患の治療戦略（薬物治療と手術の最前線）(島﨑　潤編)2016
- Author(s)
  奥村直毅
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K10885
[Book] 確定診断と治療の進め方／角膜内皮障害と水疱性角膜症, 敵状角膜とFuchs角膜内皮ジストロフィ. 角膜疾患外来でこう診てこう治せ　改訂第2版2015
- Author(s)
  奥村直毅
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-15K10885
[Book] 確定診断と治療の進め方／角膜内皮障害と水疱性角膜症, PPCDとPCV. 角膜疾患外来でこう診てこう治せ　改訂第2版2015
- Author(s)
  奥村直毅
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Shotgun proteomics identification of proteins expressed in the Descemet's membrane of patients with Fuchs endothelial corneal dystrophy2023
- Author(s)
  Tatsuya Nakagawa, Naoki Okumura, Masaya Ikegawa, Yumiko Toyama, Takashi Nirasawa, Frederic Mascarelli, Hanielle Vaitinadapoule, Ines Aouimeur, Zhiguo He, Philippe Gain, Gilles Thuret, Noriko Koizumi
- Journal Title
  
  Scientific Reports
  
  Volume: 27 Issue: 1
- DOI
  10.1038/s41598-023-37104-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09731
[Journal Article] Transcriptome dataset of human corneal endothelium based on ribosomal RNA-depleted RNA-Seq data2020
- Author(s)
  Tokuda Yuichi、Okumura Naoki、Komori Yuya、Hanada Naoya、Tashiro Kei、Koizumi Noriko、Nakano Masakazu
- Journal Title
  
  Scientific Data
  
  Volume: 7 Issue: 1 Pages: 407-407
- DOI
  10.1038/s41597-020-00754-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07343, KAKENHI-PROJECT-18K09464
[Journal Article] Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy2019
- Author(s)
  Okumura N, Hayashi R, Nakano M, Yoshii K, Tashiro K, Sato T, Blake DJ, Aleff R, Butz M, Highsmith EW, Wieben ED, Fautsch MP, Baratz KH, Komori Y, Nakahara M, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 60(2) Issue: 2 Pages: 779-786
- DOI
  10.1167/iovs.18-25760
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464, KAKENHI-PROJECT-17H04046
[Journal Article] Stability, safety, and pharmacokinetics of ganciclovir eye drops prepared from ganciclovir for intravenous infusion2019
- Author(s)
  Okumura N, Tanaka T, Fukui Y, Koizumi N
- Journal Title
  
  Jpn J Ophthalmol
  
  Volume: 63(3) Issue: 3 Pages: 289-296
- DOI
  10.1007/s10384-019-00665-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09464
[Journal Article] Feasibility of a cryopreservation of cultured human corneal endothelial cells2019
- Author(s)
  Okumura N, Kagami T, Watanabe K, Kadoya S, Sato M, Koizumi N
- Journal Title
  
  PLoS One
  
  Volume: 14(6) Issue: 6 Pages: e0218431-e0218431
- DOI
  10.1371/journal.pone.0218431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09464
[Journal Article] Association of rs613872 and Trinucleotide Repeat Expansion in the TCF4 Gene of German Patients With Fuchs Endothelial Corneal Dystrophy2019
- Author(s)
  Okumura N, Hayashi R, Nakano M, Tashiro K, Yoshii K, Aleff R, Butz M, Highsmith EW, Wieben ED, Fautsch MP, Baratz KH, Komori Y, Ueda E, Nakahara M, Weller J, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N
- Journal Title
  
  Cornea
  
  Volume: 38(7) Issue: 7 Pages: 799-805
- DOI
  10.1097/ico.0000000000001952
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464, KAKENHI-PROJECT-17H04046
[Journal Article] Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Corneal Endothelial Cell Proliferation2018
- Author(s)
  Nakahara M, Okumura N, Nakano S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 59(10) Issue: 10 Pages: 4218-4227
- DOI
  10.1167/iovs.18-24394
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09464
[Journal Article] Involvement of Nectin-Afadin in the Adherens Junctions of the Corneal Endothelium2018
- Author(s)
  Okumura N, Kagami T, Fujii K, Nakahara M, Koizumi N
- Journal Title
  
  Cornea
  
  Volume: 37(5) Issue: 5 Pages: 633-640
- DOI
  10.1097/ico.0000000000001526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09464
[Journal Article] Immune Cells on the Donor Corneal Endothelium After Corneal Transplantation2018
- Author(s)
  Okumura N, Inoue R, Nakano S, Imai H, Matsumoto D, Kayukawa K, Wakimasu K, Kitazawa K, Koizumi N, Kinoshita S
- Journal Title
  
  Cornea
  
  Volume: 37(9) Issue: 9 Pages: 1081-1086
- DOI
  10.1097/ico.0000000000001678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09464, KAKENHI-PROJECT-18K16930
[Journal Article] Development of Cell Analysis Software to Evaluate Fibroblastic Changes in Cultivated Corneal Endothelial Cells for Quality Control2018
- Author(s)
  Okumura N, Kobayashi K, Ishida N, Kagami T, Hiwa S, Hiroyasu T, Koizumi N
- Journal Title
  
  Cornea
  
  Volume: 37(12) Issue: 12 Pages: 1572-1578
- DOI
  10.1097/ico.0000000000001757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09464
[Journal Article] Perspective of Future Potent Therapies for Fuchs Endothelial Corneal Dystrophy2018
- Author(s)
  Okumura N, Hayashi R, Koizumi N
- Journal Title
  
  Open Ophthalmol J
  
  Volume: 12 Issue: 1 Pages: 154-163
- DOI
  10.2174/1874364101812010154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09464, KAKENHI-PROJECT-16K11307
[Journal Article] Effect of Trabeculotomy on Corneal Endothelial Cell Loss in Cases of After Penetrating-Keratoplasty Glaucoma.2017
- Author(s)
  Kusakabe A, Okumura N, Wakimasu K, Kayukawa K, Kondo M, Koizumi N, Sotozono C, Kinoshita S, Mori K
- Journal Title
  
  Cornea.
  
  Volume: 36(3) Issue: 3 Pages: 317-321
- DOI
  10.1097/ico.0000000000001088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Immune Cells on the Corneal Endothelium of an Allogeneic Corneal Transplantation Rabbit Model.2017
- Author(s)
  Koudouna E, Okumura N, Okazaki Y, Nakano S, Inoue R, Fullwood N, Hori J, Kinoshita S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: Vol.58 Issue: 1 Pages: 242-251
- DOI
  10.1167/iovs.16-20019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy2017
- Author(s)
  Okumura N, Hashimoto K, Kitahara M, Okuda H, Ueda E, Watanabe K, Nakahara M, Sato T, Kinoshita S, Tourtas T, Schlötzer-Schrehardt U, Kruse FE, Koizumi N
- Journal Title
  
  Sci Rep
  
  Volume: 7（1） Issue: 1 Pages: 6801-6801
- DOI
  10.1038/s41598-017-06924-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885, KAKENHI-PROJECT-16K11307
[Journal Article] Sustained activation of the unfolded protein response induces cell death in Fuchs endothelial corneal dystrophy2017
- Author(s)
  Okumura N, Kitahara M, Okuda H, Hashimoto K, Ueda E, Nakahara N, Kinoshita S, Young RD, Quantock AJ, Tourtas T, Schlötzer-Schrehardt U, Kruse FE, Koizumi N
- Journal Title
  
  Invest Ophthalmol
  
  Volume: 58（9） Issue: 9 Pages: 3697-3707
- DOI
  10.1167/iovs.16-21023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885, KAKENHI-PROJECT-16K11307
[Journal Article] The Role of Rho kinase Inhibitors in Corneal Endothelial Dysfunction2017
- Author(s)
  Okumura N, Kinoshita S, Koizumi N
- Journal Title
  
  Curr Pharm Des
  
  Volume: 23（4） Issue: 4 Pages: 660-666
- DOI
  10.2174/1381612822666161205110027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Activation of the Rho/Rho Kinase Signaling Pathway Is Involved in Cell Death of Corneal Endothelium.2016
- Author(s)
  Okumura N, Fujii K, Kagami K, Nakahara M, Kitahara M, Kinoshita S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: Vol.57 Issue: 15 Pages: 6843-6851
- DOI
  10.1167/iovs.16-20123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction.2016
- Author(s)
  Okumura N, Kakutani K, Inoue R, Matsumoto D, Shimada T, Nakahara M, Kiyanagi Y, Itoh T, Koizumi N:
- Journal Title
  
  PLoS ONE.
  
  Volume: 11(6) Issue: 6 Pages: e0158427-e0158427
- DOI
  10.1371/journal.pone.0158427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Rhoキナーゼ阻害薬であるリパスジルの角膜内皮細胞形態への影響2016
- Author(s)
  奥村直毅、岡崎友吾、井上亮太、中野新一郎、Nigel J. Fullwood、木下茂、小泉範子
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 120(4) Pages: 326-326
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Rhoキナーゼ阻害薬（リパスジル）の角膜内皮創傷治癒に対する影響2016
- Author(s)
  奥村直毅、岡崎友吾、井上亮太、角谷和哉、中野新一郎、木下茂、小泉範子
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 120（7) Pages: 503-503
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction.2016
- Author(s)
  Okumura N, Sakamoto Y, Fujii K, Kitano J, Nakano S, Tsujimoto Y, Nakamura S, Ueno M, Hagiya M, Hamuro J, Matsuyama A, Suzuki S, Shiina T, Kinoshita S, Koizumi N
- Journal Title
  
  Sci Rep.
  
  Volume: 18;6 Issue: 1
- DOI
  10.1038/srep26113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] エイジングからみたFuchs角膜内皮ジストロフィ2016
- Author(s)
  奥村直毅、小泉範子
- Journal Title
  
  眼科
  
  Volume: Vol58，No6 Pages: 619-625
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Effect of the Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) on Corneal Endothelial Wound Healing.2016
- Author(s)
  Okumura N, Okazaki Y, Inoue R, Kakutani K, Nakano S, Kinoshita S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 57(3) Issue: 3 Pages: 1284-1292
- DOI
  10.1167/iovs.15-18586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10885, KAKENHI-PROJECT-16K11307
[Journal Article] Fuchs 角膜内皮ジストロフィ治療の未来像2016
- Author(s)
  奥村直毅
- Journal Title
  
  あたらしい眼科
  
  Volume: 33(4) Pages: 511-516
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Density-gradient centrifugation enables the purification of cultured corneal endothelial cells for cell therapy by eliminating senescent cells2015
- Author(s)
  Okumura N, Kusakabe A, Hirano H, Inoue R, Okazaki Y, Nakano S, Kinoshita S, Koizumi N
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 15005-15005
- DOI
  10.1038/srep15005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885, KAKENHI-PROJECT-26670760
[Journal Article] Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in the Fuchs endothelial corneal dystrophy2015
- Author(s)
  Okumura N, Minamiyama R, Ho L, Kay EP, Kawasaki S, Tourtas T, Schlötzer-Schrehardt U, KruseF, Young RD, Quantock AJ, Kinoshita S, Koizumi N
- Journal Title
  
  Laboratory Investigation
  
  Volume: 95 Issue: 11 Pages: 1291-1304
- DOI
  10.1038/labinvest.2015.111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885, KAKENHI-PROJECT-24592675
[Journal Article] Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Transiently Alters the Morphology of Corneal Endothelial Cells2015
- Author(s)
  Okumura N, Okazaki Y, Inoue R, Nakano S, Fullwood NJ, Kinoshita S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 56(12) Issue: 12 Pages: 7560-7567
- DOI
  10.1167/iovs.15-17887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Effect of the Rho Kinase Inhibitor Y-27632 on Wound Healing of the Corneal Endothelium2015
- Author(s)
  Okumura N, Inoue R, Okazaki Y, Nakano S, Nakagawa H, Kinoshita S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 56(10) Pages: 6067-6074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Laminin-511 and 521 enable efficient in vitro expansion of human corneal endothelial cells.2015
- Author(s)
  Okumura N, Kakutani K, Numata R, Nakahara M, Schloetzer-Schrehardt U, Kruse F, Kinoshita S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 56 Issue: 5 Pages: 2933-2942
- DOI
  10.1167/iovs.14-15163
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670760
[Journal Article] Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration2015
- Author(s)
  Nakagawa H, Koizumi N, Okumura N, Suganami H, Kinoshita S
- Journal Title
  
  PLos One
  
  Volume: 10(9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Trinucleotide Repeat Expansion in the TCF4 Gene in Fuchs’ Endothelial Corneal Dystrophy in Japanese2015
- Author(s)
  Nakano M, Okumura N, Nakagawa H, Koizumi N, Ikeda Y, Ueno M, Yoshii K, Adachi H, Aleff R, Butz M, Highsmith E, Tashiro K, Wieben E, Kinoshita S, Baratz K
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 56(8) Pages: 4865-4869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Laminin-511 and 521 enable efficient in vitro expansion of human corneal endothelial cells2015
- Author(s)
  Okumura N, Kakutani K, Numata R, Nakahara M, Schloetzer-Schrehardt U, Kruse F, Kinoshita S, and Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 未定
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670760
[Journal Article] Laminin-511 and 521 enable efficient in vitro expansion of human corneal endothelial cells2015
- Author(s)
  Okumura N, Kakutani K, Numata R, Nakahara M, Schlötzer-Schrehardt U, Kruse K, Kinoshita S, Koizumi N
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 56(5) Pages: 2933-2942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10885
[Journal Article] Cultivation of Corneal Endothelial Cells on a Pericellular Matrix Prepared from Human Decidua-Derived Mesenchymal Cells.2014
- Author(s)
  Numata R, Okumura N, Nakahara M, Ueno M, Kinoshita S, Kanematsu D, Kanemura Y, Sasai Y, Koizumi N
- Journal Title
  
  Plos One
  
  Volume: 2 Issue: 2 Pages: e88169-e88169
- DOI
  10.1371/journal.pone.0088169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390404, KAKENHI-PROJECT-25861660
[Journal Article] Cell-based approach for treatment of corneal endothelial dysfunction.2014
- Author(s)
  Okumura N, Kinoshita S, Koizumi N
- Journal Title
  
  Cornea
  
  Volume: 33 Issue: Supplement 11 Pages: S37-S41
- DOI
  10.1097/ico.0000000000000229
- Data Source
  KAKENHI-PROJECT-25861660
[Journal Article] New therapeutic modality for corneal endothelial disease using Rho-associated kinase inhibitor eye drops.2014
- Author(s)
  Koizumi N, Okumura N, Ueno M, Kinoshita S
- Journal Title
  
  Cornea
  
  Volume: 33 Issue: Supplement 11 Pages: S25-S31
- DOI
  10.1097/ico.0000000000000240
- Data Source
  KAKENHI-PROJECT-25861660
[Journal Article] Involvement of cyclin D and p27 in cell proliferation mediated by ROCK inhibitors Y-27632 and Y-39983 during corneal endothelium wound healing.2014
- Author(s)
  Okumura N, Nakano S, Kay EP, Numata R, Ota A, Sowa Y, Sakai T, Ueno M, Kinoshita S, Koizumi N.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: １ Issue: 1 Pages: 318-29
- DOI
  10.1167/iovs.13-12225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390404, KAKENHI-PROJECT-25861660
[Journal Article] The ROCK Inhibitor Eye Drop Accelerates Corneal Endothelium Wound Healing.2013
- Author(s)
  Okumura N, Koizumi N, Kay EP, Ueno M, Sakamoto Y, Nakamura S, Hamuro J, Kinoshita S
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 54(4) Issue: 4 Pages: 2493-2502
- DOI
  10.1167/iovs.12-11320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659818, KAKENHI-PROJECT-25861660
[Journal Article] Inhibition of TGF-β signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine2013
- Author(s)
  Okumura N
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] Rho-associated kinase (ROCK) inhibitor eye drop treatment as a possible medical treatment for Fuchs corneal dystrophy.2013
- Author(s)
  Koizumi N, Okumura N, Ueno M, Nakagawa H, Hamuro J, Kinoshita S
- Journal Title
  
  Cornea
  
  Volume: 32(8) Issue: 8 Pages: 1167-70
- DOI
  10.1097/ico.0b013e318285475d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861660
[Journal Article] Ferret animal model of corneal endothelial dysfunction for evaluation of drug effect on corneal endothelial wound healing.2013
- Author(s)
  Sakamoto Y, Okumura N, Koizumi N, Numata R, Kitano J, Yamamoto M, Komada T, Hoshi N
- Journal Title
  
  Anim. Eye Res
  
  Volume: 32 Pages: 5-21
- NAID
  130005061465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861660
[Journal Article] Corneal endothelial expansion promoted by human bone marrow mesenchymal stem cell-derived conditioned medium.2013
- Author(s)
  Nakahara M, Okumura N, Kay EP, Hagiya M, Imagawa K, Hosoda Y, Kinoshita S, Koizumi N.
- Journal Title
  
  PLOS ONE
  
  Volume: 7 Issue: 7 Pages: e69009-e69009
- DOI
  10.1371/journal.pone.0069009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390404, KAKENHI-PROJECT-25861660
[Journal Article] Author Response: Human Corneal Endothelium Regeneration: Effect of ROCK Inhibitor.2013
- Author(s)
  Koizumi N, Okumura N, Kinoshita S
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 19;54(8) Issue: 8 Pages: 5594-5
- DOI
  10.1167/iovs.13-12813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861660
[Journal Article] Inhibition of TGF-β signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine2013
- Author(s)
  Okumura N, Kay EP, Nakahara M, Hamuro J, Kinoshita S, Koizumi N
- Journal Title
  
  PLoS ONE
  
  Volume: 8(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] Inhibition of TGF-β signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine.2013
- Author(s)
  Okumura N, Kay EP, Nakahara M, Hamuro J, Kinoshita S, Koizumi N
- Journal Title
  
  PLoS ONE
  
  Volume: 8(2) Issue: 2 Pages: e58000-e58000
- DOI
  10.1371/journal.pone.0058000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659818
[Journal Article] Corneal Endothelial Cell Fate is Maintained by LGR5 via the Regulation of Hedgehog and Wnt Pathway.2013
- Author(s)
  Hirata-Tominaga K, Nakamura T, Okumura N, Kay EP, Barrandon Y, Koizumi N, Kinoshita S
- Journal Title
  
  Stem Cells
  
  Volume: 7 Issue: 7 Pages: 1396-1407
- DOI
  10.1002/stem.1390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390404, KAKENHI-PROJECT-23592621, KAKENHI-PROJECT-24592675, KAKENHI-PROJECT-25861660
[Journal Article] et al: A ROCK inhibitor converts corneal endothelial cells into a phenotype capable of regenerating in vivo endothelial tissue2012
- Author(s)
  Okumura N, Koizumi N, Ueno M
- Journal Title
  
  Am J Pathol
  
  Volume: 181(7) Pages: 268-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma2012
- Author(s)
  Yamamoto M, Quantock AJ, Young RD, Okumura N, Ueno M, Sakamoto Y,Kinoshita S, Koizumi N
- Journal Title
  
  stroma.Mol Vis
  
  Volume: 18 Pages: 1727-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] A Study of Host Corneal Endothelial Cells After Non-Descemet Stripping Automated Endothelial Keratoplasty2012
- Author(s)
  Hatanaka H, Koizumi N, Okumura N, Takahashi H, Tanioka H, Young RD,Jones FE, Quantock AJ, Kinoshita S
- Journal Title
  
  Cornea
  
  Volume: 32(1) Pages: 76-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma.2012
- Author(s)
  Yamamoto M, Quantock AJ, Young RD, Okumura N, Ueno M, Sakamoto Y,Kinoshita S,Koizumi N
- Journal Title
  
  Mol Vis
  
  Volume: 18 Pages: 1727-1739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659818
[Journal Article] Development of new therapeutic modalities for corneal endothelial disease focused on the proliferation of corneal endothelial cells using animal models2012
- Author(s)
  Koizumi N, Okumura N, Kinoshita S
- Journal Title
  
  Exp Eye Res.
  
  Volume: 95(1) Pages: 60-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] A ROCK inhibitor converts corneal endothelial cells into a phenotype capable of regenerating in vivo endothelial tissue.2012
- Author(s)
  Okumura N, Koizumi N, Ueno M, et al
- Journal Title
  
  Am J Pathol
  
  Volume: 181(7) Issue: 1 Pages: 268-277
- DOI
  10.1016/j.ajpath.2012.03.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659818
[Journal Article] A ROCK inhibitor converts corneal endothelial cells into a phenotype capable of regenerating in vivo endothelial tissue2012
- Author(s)
  Okumura N
- Journal Title
  
  Am J Pathol.
  
  Volume: 181 Pages: 268-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] Development of new therapeutic modalities for corneal endothelial disease focused on the proliferation of corneal endothelial cells using animal models2012
- Author(s)
  Koizumi N, Okumura N, Kinoshita S
- Journal Title
  
  Exp Eye Res
  
  Volume: 95(1) Issue: 1 Pages: 60-67
- DOI
  10.1016/j.exer.2011.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659818
[Journal Article] A selective inhibitor of the Rho kinase pathway, Y -27632, and its influence on wound healing in the corneal stroma2012
- Author(s)
  Yamamoto M, Quantock AJ, Young RD, Okumura N, Ueno M, Sakamoto Y,Kinoshita S, Koizumi N
- Journal Title
  
  Mol Vis
  
  Volume: 18 Pages: 1727-1739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659818
[Journal Article] Epithelial-MesenchymalTransition-Like Phenotypic Changes of Retinal Pigment Epithelium Induced by TGFβ are Prevented by PPARγ Agonists2012
- Author(s)
  Hatanaka H, Koizumi N, Okumura N, Kay EP, Mizuhara E, Hamuro J, Kinoshita S
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 5;53(11) Pages: 6955-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] Enhancement of corneal endothelium wound healing by Rho-associated kinase (ROCK) inhibitor eye drops.2011
- Author(s)
  Okumura N, Koizumi N, Ueno M, ほか
- Journal Title
  
  British Journal of Ophthalmology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890160
[Journal Article] Development of new therapeutic modalities for corneal endothelial disease focused on the proliferation of corneal endothelial cells using animal models.2011
- Author(s)
  Koizumi N, Okumura N, Kinoshita S
- Journal Title
  
  Exp Eye Res.
  
  Volume: 95 Pages: 60-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791998
[Journal Article] Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor2009
- Author(s)
  Okumura N, Koizumi N, Kinoshita S, et al
- Journal Title
  
  Invest Ophthalmol Vis Sci. 50(8)
  
  Pages: 3680-3687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592083
[Presentation] Effect of CTG repeat expansion in TCF4 on the pathophysiology of Fuchs endothelial corneal dystrophy.2020
- Author(s)
  Matsuo H, Okumura N, Komori Y, Tokunaga A, Nakayama G, Nakahara M, Blake DJ, Tourtas T, Schlötzer-Schrehardt U, Kruse FE, and Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 角膜疾患基礎研究の進め方：臨床応用を目指した角膜内皮細胞をターゲットとした基礎研究2020
- Author(s)
  奥村直毅
- Organizer
  第124回日本眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Clinical Research and Future Perspectives of Cultured Corneal Endothelial Cell-Injection Therapy2019
- Author(s)
  Okumura, N
- Organizer
  The 122th Annual meeting of Korean Ophthalmological Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] アカデミア発シーズによる新しい角膜内皮治療法の開発2019
- Author(s)
  奥村直毅
- Organizer
  2nd NETNAS(Network of New Academic Society)
- Invited
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Association of trinucleotide repeat expansion length in TCF4 with the severity of Fuchs Endothelial Corneal Dystrophy2019
- Author(s)
  Komori Y, Okumura N, J. Weller, Nakano M, Tashiro K, Yoshii K, Aleff R, Butz M, Edward W. Highsmith EW, Wieben ED, Fautsch MP, Baratz KH, Tourtas T, Schlötzer-Schrehardt U, KruseF, Koizumi N
- Organizer
  The 10th EuCornea Congress Paris 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Drug discovery for the treatment of Fuchs corneal endothelial dystrophy by cellbased drug screening system2019
- Author(s)
  Nakagawa R, Okumura N, Onishi T, Oshima T, Ueda E, Watanabe K, T. Tourtas, U. Schlotzer-Schrehardt, F. E. Kruse, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Involvement of caspase 7 in the excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy2019
- Author(s)
  Tonomura S, Okumura N, Endo M, Nakahara M, Tourtas T, Schlotzer-Schrehardt U, F. E. Kruse, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Involvement of a disintegrin and metalloproteinase 10 (ADAM10) in excessive extracellular matrix production in Fuchs endothelial corneal dystrophy2019
- Author(s)
  Komori Y, Okumura N, Hanada N, Tokunaga A, Tourtas T, U. Schlotzer-Schrehardt, F. E. Kruse, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Feasibility of storage of cultured corneal endothelial cells as a form of cell suspension for cell-based therapy of corneal endothelial decompensation2019
- Author(s)
  Imai H, Okumura N, Kobayashi H, Takakubo K, Kurosawa T, Fukushima K, Koizumi N
- Organizer
  The 10th EuCornea Congress Paris 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 角膜内皮疾患治療の近未来2019
- Author(s)
  奥村直毅
- Organizer
  熊本眼疾患フォーラム第69回熊本眼疾患研究会・第390回熊本県眼科医会研修会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Can cell-based therapy and eye-drop medication become future therapies for the treatment of corneal endothelial disease?2019
- Author(s)
  Okumura, N
- Organizer
  ARVO-INDIA 2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Feasibility of mTOR inhibitor for the treatment of Fuchs endothelial corneal dystrophy2019
- Author(s)
  Nakayama G, Okumura N, Oshima T, Ueda E, Watanabe K, T. Tourtas, U. Schlotzer-Schrehardt, F. E. Kruse, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Establishment of a drug screening system for Fuchs endothelial corneal dystrophy2018
- Author(s)
  Oshima T, Okumura N, Onishi T, Ueda E, Watanabe K, T Tourtas, U Schlotzer-Schrehardt, F E Kruse, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 角膜内皮細胞の局所動画からの広域画像自動生成2018
- Author(s)
  小林渓太郎、奥村直毅、小泉範子、日和悟、廣安知之
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィにおけるmTOR阻害剤による細胞死抑制の作用機序2018
- Author(s)
  中山元太、奥村直毅、大嶋剛史、上田江美、渡辺恭子、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Future therapy: cell-based therapy and drug treatment2018
- Author(s)
  Okumura N
- Organizer
  The Association for Research in Vision and Ophthalmology 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Application of Rho Kinase Inhibitors for the Treatment of Corneal Endothelial Diseases2018
- Author(s)
  Okumura N
- Organizer
  APAO2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 培養ヒト角膜内皮細胞の凍結保存の検討2018
- Author(s)
  角谷紗織、奥村直毅、各務貴斗、佐藤正和、渡辺恭子、中原マキ子、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Association of rs613872 and trinucleotide repeat expansion in the TCF4 gene in Fuchs endothelial corneal dystrophy in Germany2018
- Author(s)
  Komori Y, Okumura N, Hayashi R, Nakano M, Tashiro K, Yoshii K, R Aleff, M Butz, E W Highsmith, E Wieben, M P Fautsch, K H Baratz, T Tourtas, U Schlotzer-Schrehardt, F E Kruse, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 細胞懸濁液として保存した培養角膜細胞を用いた注入療法の非臨床試験2018
- Author(s)
  今井博文、奥村直毅、小林弘明、髙久保宏基、黒沢哲太、福島健生、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 点滴静注用デノシンより自家調整したガンシクロビル点眼液の安定性2018
- Author(s)
  田中壽恭、奥村直毅、福井佑弥、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Cell-based Therapy for Corneal Endothelial Dysfunction2018
- Author(s)
  奥村直毅
- Organizer
  第72回日本臨床眼科学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 培養ヒト角膜内皮細胞移植の実用化を目指した細胞懸濁液の保存法の検討2018
- Author(s)
  福島健生、奥村直毅、上田江美、中原マキ子、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 培養ヒト角膜内皮細胞の凍結保存の検討2018
- Author(s)
  角谷紗織、奥村直毅、各務貴斗、佐藤正和、渡辺恭子、中原マキ子、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Involvement of mitochondria-associated endoplasmic reticulum membrane in the pathophysiology of Fuchs endothelial corneal dystrophy2018
- Author(s)
  Matsumoto S, Okumura N, Okuda H, Ursula Schlötzer-Schrehardt, Friedrich E. Kruse, Robert D. Young, Andrew J. Quantock, and Koizumi N
- Organizer
  The 11th Joint Meeting of Japan-China-Korea Ophthalmologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Feasibility of “stromal sandwich” for the treatment of keratoconus and keratectasia by using decellularized porcine corneal sheet2018
- Author(s)
  Hirono Y, Okumura N, Fukui Y, Matsumoto D, Takakubo K, Imai H, Kurosawa T, Fan-Wei Tseng, Dar-Jen Hsieh, Koizumi N
- Organizer
  The 11th Joint Meeting of Japan-China-Korea Ophthalmologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 自家調整ガンシクロビル点眼液の眼刺激性および薬物動態に関する検討2018
- Author(s)
  福井佑弥、奥村直毅、田中壽恭、今井博文、黒沢哲太、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] トーリセル®点滴静注液を用いた点眼液における安全性および薬物動態に関する検討2018
- Author(s)
  黒沢哲太、奥村直毅、福井佑弥、田中壽恭、今井博文、髙久保宏基、小林弘明、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Feasibility of decellularized porcine corneal sheet implantation for a “stromal sandwich” for the treatment of keratoconus and keratectasia2018
- Author(s)
  Fukui Y, Okumura N, Matsumoto D, Shimada T, Teramoto M, Imai H, Kurosawa T, F Tseng, D Hsieh, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 薬剤スクリーニングによるフックス角膜内皮ジストロフィの治療薬の探索2018
- Author(s)
  中川理咲子、奥村直毅、大西貴子、大嶋剛史、上田江美、渡辺恭子、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィ患者角膜内皮におけるTCF4発現量の検討2018
- Author(s)
  小森裕也, 奥村直毅、林良祐、中野正和、吉井健悟、Theofilos Tourtas、Friedrich E. Kruse、Ursula Schlötzer-Schrehardt、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィ患者の角膜内皮細胞におけるCTG反復配列の解析2018
- Author(s)
  徳永歩、奥村直毅、小森裕也、中原マキ子、Theofilos Tourtas、Friedrich E. Kruse、Ursula Schlötzer-Schrehardt、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィ患者の角膜内皮細胞におけるCTG反復配列の解析2018
- Author(s)
  徳永歩、奥村直毅、小森裕也、中原マキ子、Theofilos Tourtas、Friedrich E. Kruse、Ursula Schlötzer-Schrehardt、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィにおけるTCF4と上皮間葉転換の関連性の検討2018
- Author(s)
  佐藤正和、奥村直毅、徳永歩、中原マキ子、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィ患者角膜内皮におけるTCF4発現量の検討2018
- Author(s)
  小森裕也、奥村直毅、林良祐、中野正和、吉井健悟、Theofilos Tourtas、Friedrich E. Kruse、Ursula Schlötzer-Schrehardt、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] The role of TCF4 in the pathophysiology of Fuchs endothelial corneal dystrophy2018
- Author(s)
  Sato M, Okumura N, Nakahara M, Sato T, Kitazawa K, U. Schlotzer-Schrehardt, F. E. Kruse, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Future pharmaceutical treatment for the treatment of Fuchs’ endothelial corneal dystrophy2018
- Author(s)
  Okumura N
- Organizer
  BBSRC Japan Partnering Award Symposium, Eye Research in Japan and The UK and The Application of Stem Cell Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィのモデルマウスにおける角膜内皮の評価方法の確立2018
- Author(s)
  小林弘明、奥村直毅、福井佑弥、廣野雄祐、今井博文、黒沢哲太、髙久保宏基、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 点滴静注薬から自家調整したボリコナゾール点眼薬の安定性と薬物動態2018
- Author(s)
  中村日菜美、奥村直毅、福井佑弥、田中壽恭、今井博文、黒沢哲太、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィに対するmTOR阻害剤の有用性の検討2018
- Author(s)
  大嶋剛史、奥村直毅、上田江美、渡辺恭子、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 点滴静注薬から自家調整したボリコナゾール点眼薬の安定性と薬物動態2018
- Author(s)
  中村日菜美、奥村直毅、福井佑弥、田中壽恭、今井博文、黒沢哲太、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 細胞懸濁液として保存した培養角膜細胞を用いた注入療法の非臨床試験2018
- Author(s)
  今井博文、奥村直毅、小林弘明、髙久保宏基、黒沢哲太、福島健生、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィに対するmTOR阻害剤の有用性の検討2018
- Author(s)
  大嶋剛史、奥村直毅、上田江美、渡辺恭子、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Translational Research of Cultured Corneal Endothelial Cell Transplantation2018
- Author(s)
  Okumura N
- Organizer
  2018 TERMIS World Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 点滴静注用デノシン®より自家調整したガンシクロビル点眼液の安定性2018
- Author(s)
  田中壽恭, 奥村直毅, 福井祐弥, 小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] Involvement of TCF4 in the pathophysiology of Fuchs endothelial corneal dystrophy2018
- Author(s)
  Okumura N, Sato M, Nakahara M, Sato T, Kitazawa K, Schlötzer-Schrehardt U, Kruse F, Koizumi N
- Organizer
  Gordon Research Conference(GRC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] フックス角膜内皮ジストロフィに対するミトコンドリアの形態学的評価およびmTOR阻害剤の有効性評価2018
- Author(s)
  髙久保宏基、奥村直毅、福井佑弥、廣野雄祐、今井博文、黒沢哲太、小林弘明、Robert D. Young、Andrew J. Quantock、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 培養ヒト角膜内皮細胞移植の実用化を目指した細胞懸濁液の保存法の検討2018
- Author(s)
  福島健生、奥村直毅、上田江美、中原マキ子、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 角膜内皮の小胞体ストレス応答におけるmitochondria-associated ER membranesの関与2018
- Author(s)
  松本紗季、奥村直毅、奥田浩和、Robert Young、Andrew Quantock、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] 薬剤スクリーニングによるフックス角膜内皮ジストロフィの治療薬の探索2018
- Author(s)
  中川理咲子、奥村直毅、大西貴子、大嶋剛史、上田江美、渡辺恭子、小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィにおけるTCF4と上皮間葉転換の関連性の検討2018
- Author(s)
  佐藤正和, 奥村直毅, 徳永歩, 中原マキ子, 小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィにおけるmTOR阻害剤による細胞死抑制の作用機序2018
- Author(s)
  中山元太、奥村直毅、大嶋剛史、上田江美、渡辺恭子、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィに対するカスパーゼ阻害剤の有用性の検討2018
- Author(s)
  殿村茂仁, 奥村直毅, 遠藤眞子, 小泉範子
- Organizer
  第8回同志社大学先端医工学研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィに対するカスパーゼ阻害剤の有用性の検討2018
- Author(s)
  殿村茂仁、奥村直毅、遠藤眞子、小泉範子
- Organizer
  角膜カンファランス2019第43回日本角膜学会総会・第35回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09464
[Presentation] フックス角膜内皮ジストロフィにおける小胞体ストレスに対するTGF-βシグナルの影響2017
- Author(s)
  奥村直毅、上田江美、Theofilos Tourtas、Friedrich E. Kruse、Schlotzer-Schrehardt U、小泉範子
- Organizer
  角膜カンファランス2017第41回日本角膜学会総会・第33回日本角膜移植学会
- Place of Presentation
  アクロス福岡(福岡県・福岡市)
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Development of a pharmaceutical treatment for Fuchs’ Endothelial Corneal Dystrophy2017
- Author(s)
  Okumura N
- Organizer
  Stem Cells & the Eye Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Feasibility of TGF-β inhibition for the treatment of Fuchs endothelial corneal dystrophy2017
- Author(s)
  Okumura N, Hashimoto K, Okuda H, Ueda E, Tourtas T, Schlötzer-Schrehardt U, Kruse FE, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] p38 MAPキナーゼ阻害剤のヒト角膜内皮細胞培養における有用性の検討.2016
- Author(s)
  本郷茜, 奥村直毅, 中原マキ子, 小泉範子
- Organizer
  角膜カンファランス2016 第40回日本角膜学会総会第32回日本角膜移植学会
- Place of Presentation
  長野, 軽井沢プリンスホテルウエスト
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] p38 MAPキナーゼ阻害剤のヒト角膜内皮細胞培養における有用性の検討.2016
- Author(s)
  本郷茜, 奥村直毅, 中原マキ子, 小泉範子
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪, 大阪国際会議場
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] 角膜内皮障害モデルにおけるRipasudilの有用性の検討2016
- Author(s)
  奥村直毅、岡崎友吾、井上亮太、中野新一郎、木下茂、小泉範子
- Organizer
  角膜カンファランス2016第40回日本角膜学会総会・第32回日本角膜移植学会
- Place of Presentation
  長野（軽井沢プリンスホテルウエスト）
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Fuchs角膜内皮ジストロフィにおける変性タンパク質と小胞体ストレス応答．2016
- Author(s)
  奥村直毅、北原美優、橋本佳佑、Theofilos Tourtas、Schlotzer-Schrehardt U、Friedrich E. Kruse、小泉範子
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台国際センター(宮城県・仙台市)
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Sustained Activation of Unfolded Protein Response Induces Cell Death in Fuchs Endothelial Corneal Dystrophy.2016
- Author(s)
  Okumura N
- Organizer
  The 5th Biennial Scientific Meeting Asia Cornea Society
- Place of Presentation
  Seoul（Korea）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] 水疱性角膜症患者の血清中および前房水中サイトカインプロファイルの検討.2016
- Author(s)
  上野盛夫, 戸田宗豊, 平賀朝子, 小泉範子, 奥村直毅, 浅田和子, 外園千恵, 羽室淳爾, 木下茂.
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-26293376
[Presentation] Cell-based Therapy for Treating Corneal Endothelial Dysfunction.2016
- Author(s)
  Okumura N
- Organizer
  TERMIS-AP 2016 Annual Conference
- Place of Presentation
  Taipei（Taiwan）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] 培養角膜内皮細胞移植の治療効果に対する細胞密度の影響.2016
- Author(s)
  日下部綾香, 奥村直毅, 平野浩惇, 井上亮太, 岡崎友吾, 角谷和哉, 木下茂, 小泉範子
- Organizer
  角膜カンファランス2016 第40回日本角膜学会総会第32回日本角膜移植学会
- Place of Presentation
  長野, 軽井沢プリンスホテルウエスト
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] Unfolded protein accumulation induced endoplasmic reticulum stress of corneal endothelial cells in Fuchs endothelial corneal dystrophy.2016
- Author(s)
  Okumura N, Hashimoto K, Kitahara M, Nakahara M, Kinoshita S, Tourtas T, Schlotzer-Schrehardt U, Kruse F, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2016
- Place of Presentation
  Seattle（USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Cell-based therapy for treating corneal endothelial dysfunction.2016
- Author(s)
  Okumura N
- Organizer
  The 11th Catholic International Stem Cell Symposium
- Place of Presentation
  Seoul（Korea）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] 角膜内皮障害におけるトランスレーショナルリサーチ2016
- Author(s)
  奥村直毅
- Organizer
  第153回和歌山眼科学会
- Place of Presentation
  ホテルグランヴィア(和歌山県・和歌山市)
- Invited
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Profiles of cytokines in the aqueous humor and serum of bullous keratopathy patients.2016
- Author(s)
  Ueno M, Toda M, Hiraga A, Wakimasu K, Koizumi N, Okumura N, Kazuko A, Sotozono C, Hamuro J, KInoshita S.
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle, WA, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293376
[Presentation] Cultivaled Corneal Endothelial Cell Transplantation2016
- Author(s)
  Okumura N
- Organizer
  The 31st Asia-Pacific Academy of Ophthalmology Congress (APAO 2016)
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-03-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Endotheial Cell Transplantation and Regeneration2015
- Author(s)
  Okumura N
- Organizer
  DOG congress 2015
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-10-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] ラミニン511-E8フラグメントの角膜内皮細胞の基質接着性に対する影響2015
- Author(s)
  角谷和哉, 奥村直毅, 沼田諒平, Ursula Schloetzer-Schrehardt, Friedrich E. Kruse, 木下茂, 小泉範子
- Organizer
  角膜カンファランス2015 第39回日本角膜学会総会・第31回日本角膜移植学会
- Place of Presentation
  高知
- Year and Date
  2015-02-12
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] Investigation of the donor tissue information on the phenotypes of cultivated human corneal endothelium.2015
- Author(s)
  2.Hiroshi Tanaka, Morio Ueno, Munetoyo Toda, Junji Hamuro, Kengo Yoshii, Noriko Koizumi, Naoki Okumura, Shigeru Kinoshita, Monty Montoya, Bernie Iliakis.
- Organizer
  ARVO2016
- Place of Presentation
  Denver
- Year and Date
  2015-05-03
- Data Source
  KAKENHI-PROJECT-26293376
[Presentation] Purification of high cell density cultured corneal endothelial cell by density-gradient centrifugation.2015
- Author(s)
  Kusakabe A, Okumura N, Hirano H, Koizumi N, Kinoshita S
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology 2015
- Place of Presentation
  Colorado, USA, Colorado Convention Center
- Year and Date
  2015-05-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] ell Therapy for the Treatment of Corneal Endothelial Dysfunction2015
- Author(s)
  Okumura N
- Organizer
  The 30th Asia-Pacific Academy of Ophthalmology Congress
- Place of Presentation
  Guangzhou, China
- Year and Date
  2015-04-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] 角膜内皮細胞の最新治療, 培養角膜内皮細胞移植2015
- Author(s)
  奥村直毅
- Organizer
  第69回日本臨床眼科学会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Year and Date
  2015-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Cell-based regenerative therapy for treating corneal endothelial dysfunction2015
- Author(s)
  Okumura N
- Organizer
  第69回日本臨床眼科学会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Year and Date
  2015-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] The feasibility of recombinant human laminin-511 E8 fragments for human corneal endothelial cell cultivation.2015
- Author(s)
  Kakutani K, Okumura N, Schlotzer-Schrehardt U, Kruse FE, Kinoshita S, Koizumi N
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology 2015
- Place of Presentation
  Colorado, USA, Colorado Convention Center
- Year and Date
  2015-05-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] 培養角膜内皮細胞移植における移植細胞の細胞密度が治療効果に与える影響2015
- Author(s)
  奥村直毅、中野新一郎、日下部綾香、井上亮太、岡崎友吾、角谷和哉、木下茂、小泉範子
- Organizer
  第119回日本眼科学会総会
- Place of Presentation
  札幌（ロイトン札幌）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] 培養角膜内皮細胞移植における移植細胞の細胞密度が治療効果に与える影響.2015
- Author(s)
  奥村直毅, 中野新一郎, 日下部綾香, 井上亮太, 岡崎友吾, 角谷和哉, 木下茂, 小泉範子
- Organizer
  第119回日本眼科学会総会
- Place of Presentation
  札幌, ロイトン札幌
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] Clinical research of cultured corneal endothelial transplantation2015
- Author(s)
  Okumura N
- Organizer
  The Association for Research in Vision and Ophthalmology 2015
- Place of Presentation
  Colorado, USA,
- Year and Date
  2015-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Fuchs Corneal Dystrophy in Asia2015
- Author(s)
  Okumura N
- Organizer
  The 30th Asia-Pacific Academy of Ophthalmology Congress
- Place of Presentation
  Guangzhou, China
- Year and Date
  2015-04-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] 培養角膜内皮細胞移植における移植細胞の細胞老化が治療効果に与える影響2015
- Author(s)
  奥村直毅、中野新一郎、日下部綾香、井上亮太、岡崎友吾、角谷和哉，木下茂、小泉範子
- Organizer
  第37回日本バイオマテリアル学会大会
- Place of Presentation
  京都(京都テルサ）
- Year and Date
  2015-11-10
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] ow to make cornea endothelial cells2015
- Author(s)
  Okumura N
- Organizer
  6th EuCornea Congress, XXXIII Congress of the ESCRS
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-09-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] 培養角膜内皮細胞移植におけるラミニン511-E8フラグメントの有用性.2015
- Author(s)
  角谷和哉, 奥村直毅, 井上亮太, 岡﨑友吾, 中野新一郎, 小泉範子
- Organizer
  第37回日本バイオマテリアル学会
- Place of Presentation
  京都, 京都テルサ
- Year and Date
  2015-11-10
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] Effect of the cell density of cultivated corneal endothelial cells on tissue engineering for the treatment of corneal endothelial dysfunction2015
- Author(s)
  Okumura N, Nakano S, Kusakabe A, Inoue R, Okazaki Y, Kakutani K, Kinoshita S, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology 2015
- Place of Presentation
  Colorado, USA,
- Year and Date
  2015-05-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10885
[Presentation] Effect of the cell density of cultivated corneal endothelial cells on tissue engineering for the treatment of corneal endothelial dysfunction.2015
- Author(s)
  Okumura N, Nakano S, Kusakabe A, Inoue R, Okazaki Y, Kakutani K, Kinoshita S, Koizumi N
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology 2015
- Place of Presentation
  Colorado, USA, Colorado Convention Center
- Year and Date
  2015-05-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] 培養角膜内皮細胞移植における移植細胞の細胞老化が治療効果に与える影響.2015
- Author(s)
  奥村直毅, 中野新一郎, 日下部綾香, 井上亮太, 岡﨑友吾, 角谷和哉, 木下茂, 小泉範子
- Organizer
  第37回日本バイオマテリアル学会
- Place of Presentation
  京都, 京都テルサ
- Year and Date
  2015-11-10
- Data Source
  KAKENHI-PROJECT-26670760
[Presentation] Development of cell therapy for treating corneal endothelial dysfunction.2014
- Author(s)
  Okumura N
- Organizer
  Seminar in the Catholic University of Korea
- Place of Presentation
  Catholic University of Korea
- Year and Date
  2014-09-23
- Invited
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Cultivated corneal endothelial cell injection for the treatment of bullous keratopathy.2014
- Author(s)
  Okumura N
- Organizer
  Seminar in Kyungpook National University Hospital
- Place of Presentation
  Kyungpook National University Hospital
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] 角膜内皮再生医療の実現化に向けて. 卓越した大学院拠点2013
- Author(s)
  奥村直毅
- Organizer
  合同リトリート
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ROCK阻害剤Y-39983の角膜内皮細胞増殖に対する効果の検討2013
- Author(s)
  中野新一郎、奥村直毅、北野絢嗣、太田礼、坂本雄二、羽室淳爾、上野盛夫、木下茂、小泉範子
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 難治性眼表面疾患に対する培養鼻粘膜上皮シートの開発2013
- Author(s)
  小林正和、中村隆宏、安田誠、畑結衣子、大倉翔貴、奥村直毅、小泉範子、久育男、木下茂
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Paradigm Shift for Corneal Endothelial Regeneration2013
- Author(s)
  Okumura N
- Organizer
  28th Asia-Pacific Academy of Ophthalmology Congress.
- Place of Presentation
  INDIA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤の角膜内皮細胞に対する増殖促進作用機序の検討2013
- Author(s)
  沼田諒平、奥村直毅、Kay EunDuck、中原マキコ、上野盛夫、木下茂、小泉範子
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ウサギ水疱性角膜症モデルを用いた培養角膜内皮細胞注入療法の開発2013
- Author(s)
  北野絢嗣、奥村直毅、山崎健太、中原マキ子、上野盛夫、羽室淳爾、木下茂、小泉範子
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 霊長類水疱性角膜症モデルを用いた培養角膜内皮細胞注入療法の有用性および安全性評価2013
- Author(s)
  奥村直毅、椎名隆、鈴木進悟、中村紳一朗、坂本雄二、上野盛夫、羽室淳爾、木下茂、松山晃文
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ポリ乳酸粒子を用いた選択的Rhoキナーゼ阻害剤徐放化の検討2013
- Author(s)
  迎田生、齋藤高志、北野絢嗣、奥村直毅、木下茂、田畑泰彦、小泉範子
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤を併用した培養角膜内皮細胞移植の開発2013
- Author(s)
  北野絢嗣、奥村直毅、上野盛夫、中原マキコ、沼田諒平、坂本雄二、羽室淳爾、木下茂、小泉範子
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤の霊長類角膜内皮細胞に対する増殖促進機序の解明2013
- Author(s)
  沼田諒平、奥村直毅、Eunduck P Kay、中原マキ子、上野盛夫、木下茂、小泉範子
- Organizer
  膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤の培養角膜内皮細胞に対する接着促進機序の検討2013
- Author(s)
  辻本勇気、奥村直毅、Eunduck P Kay、沼田諒平、上野盛夫、羽室淳爾、木下茂、小泉範子
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 選択的Rhoキナーゼ阻害剤徐放化ポリ乳酸粒子の作製2013
- Author(s)
  迎田生、齋藤高志、北野絢嗣、奥村直毅、小泉範子、田畑泰彦
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤の角膜内皮細胞に対するアポトーシス抑制効果の検討2013
- Author(s)
  小田嶋愛、奥村直毅、Eunduck P Kay、陳文、上野盛夫、木下茂、小泉範子
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤の培養角膜内皮細胞に対する基質接着性促進機序の検討2013
- Author(s)
  奥村直毅、辻本勇気、Kay EunDuck、沼田諒平、太田礼、上野盛夫、羽室淳爾、木下茂、小泉範子
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] PPARγ作動薬による霊長類網膜色素上皮細胞の線維性変化への影響2012
- Author(s)
  畑中宏樹、奥村直毅、小泉範子、水原英理、羽室淳爾、木下茂
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 霊長類水疱性角膜症モデルを用いた培養角膜内皮細胞注入治療の開発2012
- Author(s)
  小泉範子, 奥村直毅, 上野盛夫, 坂本雄二, 山崎健太, 鳥居隆三, 羽室淳爾, 木下茂
- Organizer
  11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 水疱性角膜症に対する新しい治療法の開発2012
- Author(s)
  奥村直毅
- Organizer
  角膜カンファランス2012第36回日本角膜学会総会, 第28回日本角膜移植学会,学術奨励賞受賞記念講演
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rock inhibitor eye drops accelerate corneal endothelium wound healing in a primate model2012
- Author(s)
  Okumura N, Koizumi N, Ueno M, Sakamoto Y, Takahashi H, Yamasaki K,Torii R, Hamuro J, Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 水疱性角膜症患者における選択的Rhoキナーゼ阻害剤点眼の有用性の検討2012
- Author(s)
  奥村直毅、小泉範子、坂本雄二、上野盛夫、羽室淳爾、木下茂
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ウサギ水疱性角膜内皮症モデルを用いた培養角膜内皮細胞注入療法の開発2012
- Author(s)
  北野絢嗣, 奥村直毅, 山崎健太, 中原マキ子, 沼田諒平, 上野盛夫, 羽室淳爾, 木下茂, 小泉範子
- Organizer
  第33回日本炎症・再生医学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 水疱性角膜症に対する新しい治療法の開発2012
- Author(s)
  奥村直毅
- Organizer
  参天製薬講演会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Effect of the PPARγ agonist on the fibrotic change in primate retinal pigment epithelial cells2012
- Author(s)
  Hatanaka H, Okumura N, Koizumi N, Mizuhara E, Hamuro J, Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] New Therapeutic Modality of Using ROCK Inhibitor for Corneal Endothelial Disease2012
- Author(s)
  Okumura N
- Organizer
  27th Asia-Pacific Academy of Ophthalmology Congress
- Place of Presentation
  KOREA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮障害に対する新しい治療法の開発2012
- Author(s)
  奥村直毅
- Organizer
  第21回動物生命科学研究センター学術講演会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ヒト脱落膜由来間葉細胞から作成したマトリクスを用いたヒト角膜内皮細胞培養法の検討2012
- Author(s)
  沼田諒平, 奥村直毅, 中原マキ子, 上野盛夫, 木下茂, 金村米博, 笹井芳樹, 小泉範子
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Cell-injection therapy using cultivated human corneal endothelial cells in a primate model2012
- Author(s)
  Koizumi N, Okumura N, Sakamoto Y, Yamasaki K, Nakahara M, Torii R, Ueno M, Hamuro J, Kinoshita S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 結膜扁平上皮眼におけるGPR49の発現の検討2012
- Author(s)
  平田香菜、中村隆宏、外園知恵、稲富勉、奥村直毅、小泉範子、横井則彦、木下茂
- Organizer
  角膜カンファランス2012第36回日本角膜学会総会・第28回日本角膜移植学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ヒト脱落膜由来間葉細胞から作成したマトリクスを用いたヒト角膜内皮細胞培養法の検討2012
- Author(s)
  沼田諒平、奥村直毅、中原マキ子、上野盛夫、木下茂、金村米博、笹井芳樹、小泉範子
- Organizer
  角膜カンファランス、2012第36回日本角膜学会総会・第28回日本角膜移植学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ヒト培養角膜内皮細胞を用いた角膜内皮前房注入の試み2012
- Author(s)
  小泉範子, 奥村直毅, 坂本雄二, 中原マキ子, 山崎健太, 土屋英明, 上野盛夫,羽室淳爾, 木下茂
- Organizer
  第33回日本炎症・再生医学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮治療の新たな展開2012
- Author(s)
  奥村直毅
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮障害に対する選択的Rho キナーゼ阻害剤点眼の有用性の検討2012
- Author(s)
  奥村直毅, 小泉範子, 坂本雄二, 上野盛夫, 鳥居隆三, 羽室淳爾, 木下茂
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮機能不全患者に対するRhoキナーゼ阻害剤点眼の有用性の検討2012
- Author(s)
  奥村直毅, 小泉範子, 坂本雄二, 上野盛夫, 羽室淳爾, 木下茂
- Organizer
  第33回日本炎症・再生医学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Cultivation of human corneal endothelial cells on a pericellular matrix prepared from human decidua-derived mesenchymal cells2012
- Author(s)
  Numata R, Okumura N, Nakahara M, Ueno M, Kinoshita S, Kanemura Y, Sasai Y, Koizumi N
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ヒト培養角膜内皮細胞を用いた角膜内皮前房注入治療の試み2012
- Author(s)
  小泉範子、奥村直毅、坂本雄二、山崎健太
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Elevated keratan sulphate in the corneal stroma cultured at low oxygen tension2012
- Author(s)
  Leona T. Y. Ho, Bruce Caterson, Keith M. Meek, Andrew J. Quantock, Naoki Okumura Noriko Koizumi
- Organizer
  角膜カンファランス2012第36回日本角膜学会総会・第28回日本角膜移植学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮の再生医療2012
- Author(s)
  奥村直毅
- Organizer
  日本角膜移植学会・日本角膜学会共催懇談会「角膜再生医療の最先端と将来展望」
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 霊長類角膜内皮障害モデルを用いた選択的Rhoキナーゼ阻害剤点眼治療法の開発2012
- Author(s)
  奥村直毅、小泉範子、坂本雄二、鳥居隆三、上野盛夫、羽室淳爾、木下茂
- Organizer
  角膜カンファランス2012第36回日本角膜学会総会・第28回日本角膜移植学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ROCK Inhibitor Regulates the G1-S Progression of Corneal Endothelial Cells2011
- Author(s)
  Naoki Okumura Noriko Koizumi, Kenta Yamasaki, Morio Ueno, Yuji Sakamoto, Yoshihiro Sowa, Toshiyuki Sakai, Junji Hamuro, Shigeru Kinoshita
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ROCK inhibitor as a new therapeutic modality for corneal endothelial dysfunction2011
- Author(s)
  Okumura N
- Organizer
  5th International Symposium of the UCSD-Doshisha Medical Imaging Research Center
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Cell-Injection Therapy using Cultivated Corneal Endothelial Cells Combined with a ROCK Inhibitor in a Primate Model2011
- Author(s)
  Noriko Koizumi, Naoki Okumura, Kenta Yamasaki, Morio Ueno, Yuji Sakamoto, Hiroaki Takahashi, Ryuzo Torii, Junji Hamuro, Shigeru Kinoshita
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale,Florida, USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 選択的Rhoキナーゼ阻害剤による角膜内皮細胞の細胞周期に対する影響2011
- Author(s)
  奥村直毅, 小泉範子, ほか
- Organizer
  第35回角膜カンファランス
- Place of Presentation
  品川プリンスホテル、東京
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-22890160
[Presentation] 水疱性角膜症患者における選択的Rhoキナーゼ阻害剤点眼の有用性の検討2011
- Author(s)
  奥村直毅、小泉範子、坂本雄二、上野盛夫、羽室淳爾、木下茂
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Effect of PPARγ agonist on the fibrotic change in retinal pigment epithelium and vitreous cells2011
- Author(s)
  Hatanaka H, Okumura N, Koizumi, N, Hamuro J, Kinoshita S
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 水疱性角膜症に対する培養角膜内皮細胞注入治療の試み2011
- Author(s)
  小泉範子、奥村直毅、山崎健太、上野盛夫、坂本雄二、高橋浩昭、鳥居隆三、羽室淳爾、木下茂
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮再生医療の現状と展望2011
- Author(s)
  小泉範子, 奥村直毅, 上野盛夫,羽室淳爾, 木下茂
- Organizer
  第65回日本臨床眼科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] The New Therapeutic Modality of Using a Rho Kinase (ROCK) Inhibitor for the Treatment of Corneal Endothelial Dysfunction2011
- Author(s)
  Okumura N
- Organizer
  TERMIS
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ROCK Inhibitor Regulates the G1-S Progression of Corneal Endothelial Cells.2011
- Author(s)
  Naoki Okumura, Noriko Koizumi, Kenta Yamasaki, Morio Ueno, Yuji Sakamoto, Yoshihiro Sowa, Toshiyuki Sakai, Junji Hamuro, Shigeru Kinoshita:
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Broward County Convention Center（Florida, USA)
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害薬の角膜内皮再生医療への応用2011
- Author(s)
  奥村直毅
- Organizer
  第1回角膜Eyeの会
- Place of Presentation
  シャングリラホテル、東京(招待講演)
- Year and Date
  2011-02-25
- Data Source
  KAKENHI-PROJECT-22890160
[Presentation] PPARγ作動薬による網膜色素上皮細胞および硝子体細胞の線維性変化への影響2011
- Author(s)
  畑中宏樹、奥村直毅、小泉範子、羽室淳爾、木下茂
- Organizer
  第65回日本臨床眼科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ROCK inhibitor as a new therapeutic modality for corneal endothelial dysfunction.2011
- Author(s)
  Okumura N
- Organizer
  5th International Symposium of the UCSD-Doshisha Medical Imaging Research Center(招待講演)
- Place of Presentation
  Doshisha MedicalImaging Research Center（San Diego, USA)
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮機能不全に対する選択的Rhoキナーゼ阻害剤点眼治療法の開発2011
- Author(s)
  奥村直毅、小泉範子、上野盛夫、坂本雄二、高橋浩昭、鳥居隆三、羽室淳爾、木下茂
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  京都国際会議場（京都）
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] ROCK Inhibition Regulates the Cell Adhesion of Corneal Endothelial Cells2011
- Author(s)
  Kyoko Kumagai, Noriko Koizumi, Naoki Okumura, Kenta Yamazaki, Morio Ueno, Yuji Sakamoto, Nagahisa Yoshimura1, Junji Hamuro, Shigeru Kinoshita
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮機能不全に対する選択的Rhoキナーゼ阻害剤点眼治療法の開発2011
- Author(s)
  奥村直毅、小泉範子、上野盛夫、坂本雄二、高橋浩昭、鳥居隆三、羽室淳爾、木下茂
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] New strategy for corneal endothelial tissue engineering2011
- Author(s)
  Koizumi N, Okumura N, Kinoshita S
- Organizer
  Schepens Eye Research Institute 27th Biennial Cornea Conference
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] A New Pharmaceutical Treatment for Corneal Endothelial Dysfunction2011
- Author(s)
  Okumura N
- Organizer
  Asia-ARVO 2011
- Place of Presentation
  シンガポール(招待講演)
- Year and Date
  2011-01-20
- Data Source
  KAKENHI-PROJECT-22890160
[Presentation] 選択的Rhoキナーゼ阻害剤の角膜内皮細胞遊走への影響2010
- Author(s)
  奥村直毅, 小泉範子, ほか
- Organizer
  第114回日本眼科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-22890160
[Presentation] The efficacy of a ROCK inhibitor containing corneal storage medium for corneal endothelial cells.2010
- Author(s)
  Takahashi H, Koizumi N, Okumura N, Ueno M, Sakamoto Y, Hamuro J, Kinoshita S
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO)
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-20592083
[Presentation] A ROCK Inhibitor Eye Drop Enhances Corneal Endothelial Cell Proliferation.2010
- Author(s)
  Okumura N., Koizumi N, ほか
- Organizer
  The 2nd Asia Cornea Society Biennial Scientific Meeting
- Place of Presentation
  Kyoto,日本(招待講演)
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22890160
[Presentation] The existence of dead cells in corneal endothelium preserved with storage media.2010
- Author(s)
  Tanioka H, Kawasaki S, Adachi H, Inatomi T, Hieda O, Fukuoka H, Okumura N, Koizumi N, Iliakis B, Kinoshita S
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO)
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-20592083
[Presentation] The Effect of a ROCK Inhibitor on Corneal Endothelial Cell Migration in an in Vitro Wound-Healing Model.2010
- Author(s)
  Okumura N, Koizumi N, ほか
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida,米国
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22890160
[Presentation] Rock inhibitor eye drops accelerate corneal endothelium wound healing in a primate model.
- Author(s)
  Okumura N
- Organizer
  The Association for Research in Vision and Ophthalmology 2012
- Place of Presentation
  Florida, USA
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Integral Analysis of Gene Signatures and MicroRNA Expression of Cultured Human Corneal Endothelial Cells in Relation to Their Functions, Cell Senescence, Epithelial-Mesenchymal Transition, and Fibrosis.（口頭）
- Author(s)
  Kazuko Asada, Munetoyo Toda, Michio Hagiya, Kana Nakata, Morio Ueno, Naoki Okumura, Noriko Koizumi, Junji Hamuro, Shigeru Kinoshita
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] The establishment of human corneal endothelial cell culture for clinical application（シンポジウム）
- Author(s)
  Naoki Okumura
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] 角膜内皮細胞培養におけるラミニン511および521の有用性（口頭）
- Author(s)
  奥村直毅、沼田諒平、角谷和哉、Ursula Schlotzer、Friendrich Kruse、木下茂、小泉範子
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] 再生医療研究の最前線！トランスレーショナル・リサーチの実践（口頭）
- Author(s)
  奥村直毅
- Organizer
  第67回日本臨床眼科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Efficacy and Safety Evaluation of Cell-Injection Therapy using Cultivated Human Corneal Endothelial Cells.（口頭）
- Author(s)
  Noriko Koizumi, Naoki Okumura, Takashi Shiina, Shingo Suzuki, Shinichiro Nakamura, Yuji Sakamoto, Kenta Yamasaki, Morio Ueno, Junji Hamuro, Shigeru Kinoshita
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] The Effect of EMT-Related Genes on the Regulation of Excessive Production of Extracellular Matrix in a Cellular Model of Fuchs’ Corneal Dystrophy.
- Author(s)
  Naoki Okumura, Leona Ho, EunDuck P. Kay, Satoshi Kawasaki, Theofilos Tourtas, Ursula Schlotzer-Schrehardt, Friedrich E. Kruse, Shigeru Kinoshita, Noriko Koizumi
- Organizer
  Gordon Research Conference.
- Place of Presentation
  California, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Proliferation Propensity of Cultured Human Corneal Endothelial Cells and Their Plasticity Dictated by Culture Microenvironments.（ポスター）
- Author(s)
  Munetoyo Toda, Kana Nakata, kazuko asada, Michio Hagiya, Morio Ueno, Naoki Okumura, Noriko Koizumi, Junji Hamuro, Shigeru Kinoshita
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Regenerative medicine for the treatment of corneal endothelial dysfunction.
- Author(s)
  Okumura N
- Organizer
  TERMIS-AP 2014
- Place of Presentation
  Daegu, Korea
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Involvement of transforming growth factor beta in extracellular matrix deposition and endoplasmic reticulum stress in Fuchs' corneal dystrophy.
- Author(s)
  Okumura N, Minamiyama R, Kay EP, Ho L, Kawasaki S, Young R, Quantock A, Schlotzer-Schrehardt U, Kruse F, Kinoshita S, Koizumi N
- Organizer
  The International Society for Eye Research XXI Biennial Meeting
- Place of Presentation
  San Francisco, California, USA
- Year and Date
  2014-07-20 – 2014-07-23
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Cell Line of Fuchs' Corneal Dystrophy Produces an Abnormal Extracellular Matrix.（ポスター)
- Author(s)
  Leona Ho, Naoki Okumura, EunDuck P. Kay, Kenta Yamasaki, Satoshi Kawasaki, Theofilos Tourtas, Ursula Schlotzer-Schrehardt, Friedrich E. Kruse, Shigeru Kinoshita, Noriko Koizumi
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Development of a Human Cultivated Nasal Mucosal Epithelial Cell Sheet for the Treatment of Severe Ocular Surface Diseases.（ポスター）
- Author(s)
  Masakazu Kobayashi, Takahiro Nakamura, Makoto Yasuda, Yuiko Hata, Shoki Okura, Naoki Okumura, Noriko Koizumi, Hisao Yasu, Shigeru Kinoshita
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Fuchs角膜内皮ジストロフィにおけるECM産生に対するTGF-βシグナルの影響（ポスター）
- Author(s)
  奥村直毅、Ho Leona、Kay EunDuck、川崎諭、Tourtas Theofilos、Schlotzer Ursula、Kruse Friendrich、木下茂、小泉範子
- Organizer
  角膜カンファランス2014第38回日本角膜学会総会・第30回日本角膜移植学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Rho kinase inhibitor promotes cell adhesion of corneal endothelial cells through inhibiting phosphorylation of MLC.（ポスター）
- Author(s)
  Yuki Tsujimoto, Naoki Okumura, EunDuck P. Kay, Ryohei Numata, Shigeru Kinoshita, Noriko Koizumi
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Cell-injection Therapy Using Rho Kinase Inhibitor in a Corneal Endothelial Dysfunction Rabbit Model.（ポスター）
- Author(s)
  Junji Kitano, Naoki Okumura, EunDuck P. Kay, Morio Ueno, Junji Hamuro, Shigeru Kinoshita, Noriko Koizumi
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] 水疱性角膜症患者における選択的Rhoキナーゼ阻害剤点眼の有用性の検討
- Author(s)
  奥村直毅
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Cell-Based Approach for the Treatment of Corneal Endothelial Dysfunction.（口頭）
- Author(s)
  Naoki Okumura
- Organizer
  Gordon Research Conference
- Place of Presentation
  California, USA
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] New Therapeutic Modality of Using ROCK Inhibitor for Corneal Endothelial Disease.
- Author(s)
  Okumura N
- Organizer
  Asia-Pacific Academy of Ophthalmology Congress
- Place of Presentation
  Busan, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤の培養角膜内皮細胞に対する基質接着性促進機序の検討
- Author(s)
  奥村直毅
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Rhoキナーゼ阻害剤の角膜内皮細胞に対するアポトーシス抑制効果の検討
- Author(s)
  奥村直毅、小田嶋愛、EunDuck Kay、陳文、上野盛夫、羽室淳爾、木下茂、小泉範子
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] 角膜内皮障害に対する選択的Rho キナーゼ阻害剤点眼の有用性の検討
- Author(s)
  奥村直毅
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 角膜内皮機能不全患者に対するRhoキナーゼ阻害剤点眼の有用性の検討
- Author(s)
  奥村直毅
- Organizer
  第33回日本炎症・再生医学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Paradigm Shift for Corneal Endothelial Regeneration
- Author(s)
  Okumura N
- Organizer
  Asia-Pacific Academy of Ophthalmology Congress.
- Place of Presentation
  Hyderabad, India
- Invited
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] 霊長類水疱性角膜症モデルを用いた培養角膜内皮細胞注入療法の有用性および安全性評価
- Author(s)
  奥村直毅
- Organizer
  角膜カンファランス2013第37回日本角膜学会総会・第29回日本角膜移植学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-23791998
[Presentation] Modulating Cell Adhesion Property Enables Cell-based Therapy for Corneal Endothelial Dysfunction.
- Author(s)
  Okumura N
- Organizer
  The Association for Research in Vision and Ophthalmology 2014
- Place of Presentation
  Florida, USA
- Year and Date
  2014-05-05 – 2014-05-08
- Data Source
  KAKENHI-PROJECT-25861660
[Presentation] Rho-kinase inhibitor enhances corneal endothelial cell proliferation via p27 degradation.（ポスター）
- Author(s)
  Ryohei Numata, Naoki Okumura, EunDuck P. Kay, Makiko Nakahara, Shinichiro Nakano, Morio Ueno, Shigeru Kinoshita, Noriko Koizumi
- Organizer
  The Association for Research in Vision and Ophthalmology 2013
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861660

1. KOIZUMI Noriko (20373087)

# of Collaborated Projects: 3 results

# of Collaborated Products: 43 results
2. KINOSHITA Shigeru (30116024)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
3. TORII Ryuzou (50106647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SOTOZONO Chie (30216585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 羽室淳爾 (80536095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 上野盛夫 (40426531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. NAKANO Masakazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
8. Baratz Keith H.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Schlötzer-Schrehardt Ursula

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Kruse Friedrich

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
11. Quantock Andrew

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 徳田雄市

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 田代啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okumura Naoki 奥村 直毅

OKUMURA Naoki 奥村 直毅

Research Projects

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Co-Researchers

フックス角膜内皮ジストロフィの病態におけるスプライシング異常の意義の解明Principal Investigator

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Protein Expression Analysis in Patients with Fuchs' Endothelial Corneal Dystrophy Using MALDIPrincipal Investigator

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Effect of CTG triplet repeat expansion in TCF4 on the pathophysiology of Fuchs endothelial corneal dystrophyPrincipal Investigator

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The effect of TGC triplet repeat expansion on the pathophysiology of Fuchs endothelial corneal dystrophyPrincipal Investigator

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Paracrine interactions among human cultured corneal endothlial cells regulated the ce state transition in a paracrine fashion

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Investigation of molecular mechanism of cellular-senescence of corneal endothelial cells in association with cell-culture and its application for corneal endothelial tissue engineering

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Development of Rho kinase inhibitor eye drop as the therapy for treating corneal endothelial dysfunctionPrincipal Investigator

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The effects of the amino acid profile in tear fluid on ocular surface homeostasis and disease condition

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Development of new therapy for corneal endothelial dysfunction by modulating epithelial-mesenchymal transitionPrincipal Investigator

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角膜内皮のアポトーシス、細胞死の制御による水疱性角膜症に対する新規治療法の開発Principal Investigator

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Corneal Tissue Engineering Using Alginate

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[Book] 医学のあゆみ2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 【眼科臨床エキスパート】角結膜疾患の治療戦略（薬物治療と手術の最前線）(島﨑 潤編)2016

Author(s)

Publisher

Data Source

Okumura Naoki 奥村直毅

OKUMURA Naoki 奥村直毅

[Book] 【眼科臨床エキスパート】角結膜疾患の治療戦略（薬物治療と手術の最前線）(島﨑　潤編)2016

[Book] 確定診断と治療の進め方／角膜内皮障害と水疱性角膜症, 敵状角膜とFuchs角膜内皮ジストロフィ. 角膜疾患外来でこう診てこう治せ　改訂第2版2015

[Book] 確定診断と治療の進め方／角膜内皮障害と水疱性角膜症, PPCDとPCV. 角膜疾患外来でこう診てこう治せ　改訂第2版2015