Okae Hiroaki 岡江寛明

… Alternative Names

OKAE Hiroaki 岡江寛明

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Researcher Number	10582695
Other IDs
Affiliation (Current)	2025: 熊本大学, 発生医学研究所, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 熊本大学, 発生医学研究所, 教授 2019 – 2021: 東北大学, 医学系研究科, 准教授 2016 – 2018: 東北大学, 医学系研究科, 助教 2011 – 2015: 東北大学, 医学(系)研究科(研究院), 助教 2013: 東北大学, 医学系研究科, 助教 2011 – 2013: 東北大学, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Biological Sciences / Transformative Research Areas, Section (III) / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Obstetrics and gynecology / epigenetics Except Principal Investigator Obstetrics and gynecology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Biological Sciences
Keywords	Principal Investigator ゲノムインプリンティング / ヒト胎盤 / 胎盤 / DNAメチル化 / 幹細胞 / 栄養膜幹細胞 / 栄養膜幹細胞（TS細胞） / 栄養膜幹（TS）細胞 / 次世代シーケンサー / 胎盤幹（TS）細胞 … More / CRISPRスクリーニング / 妊娠合併症 / 妊娠高血圧腎症 / CRISPR / 妊娠高血圧症候群 / 人工胎盤 / 人工胚盤胞 / 原始内胚葉幹細胞 / 胚体外性幹細胞 / ES細胞 / 原始内胚葉幹細胞（PrES細胞） / ES/iPS細胞 / 全能性 / 胎盤トロフォブラスト幹（TS）細胞 / ダイレクトリプログラミング / エピジェネティクス / 胎盤トロフォブラスト幹（TS)細胞 / ヒト生殖細胞 / 生殖細胞 / 胎盤幹 (TS) 細胞 / ヒト胎盤幹（TS）細胞 / メチル化インプリント … More Except Principal Investigator ゲノムインプリンティング / エピジェネティクス / 生殖医学 / 生殖補助医療 / 胎盤 / エピジェネティックス / メチル化インプリント / DNAメチル化 / 数理モデル / シングル細胞マルチオーム解析 / 胚着床モデル / 免疫寛容 / 着床障害 / miRNA / 先天性インプリント異常症 / microRNA / 生殖補助医療（ART） / Oct3/4 / Cdx2 / TS細胞 / 胎盤発生 / 細胞分化 / ヒト胎盤幹細胞 / 細胞系譜 / 胎盤幹細胞 / 精子 / CHIP-on-chip法 / インプリント遺伝子 Less

ヒト幹細胞を用いた器官形成原理の構成的理解Principal Investigator
- Principal Investigator
  
  岡江寛明
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kumamoto University
ヒト胎盤の発生を支える分子基盤の包括的な理解Principal Investigator
- Principal Investigator
  
  岡江寛明
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kumamoto University
Implantation organoid model using human multilevel stem cells and elucidation of immune tolerance mechanism
- Principal Investigator
  
  有馬隆博
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
Investigation of a novel genomic imprinting mechanism in the human placentaPrincipal Investigator
- Principal Investigator
  
  岡江寛明
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kumamoto University
Innovative disease modeling of pregnancy complications using human trophoblast stem cellsPrincipal Investigator
- Principal Investigator
  
  Okae Hiroaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kumamoto University
  Tohoku University
Reconstruction of totipotency using stem cells derived from preimplantation embryosPrincipal Investigator
- Principal Investigator
  
  Hiroaki Okae
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
  Tohoku University
Investigation of the molecular basis of extraembryonic lineage specification in humansPrincipal Investigator
- Principal Investigator
  
  Hiroaki Okae
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
Epigenomic cohort study in the ART-derived children
- Principal Investigator
  
  ARIMA TAKAHIRO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Genomic imprinting in the human placentaPrincipal Investigator
- Principal Investigator
  
  Okae Hiroaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
DNA methylation analyses in the human placenta cells
- Principal Investigator
  
  Arima Takahiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
ヒト生殖細胞のエピゲノムダイナミクスとその制御機構Principal Investigator
- Principal Investigator
  
  岡江寛明
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Genomic imprinting
- Principal Investigator
  
  ARIMA TAKAHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Functional analysis of a placenta-specific imprinted gene Gab1 in the placentaPrincipal Investigator
- Principal Investigator
  
  OKAE Hiroaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  epigenetics
- Research Institution
  Tohoku University
新規ヒト・インプリンティング領域の探索と生殖補助医療への影響
- Principal Investigator
  
  ARIMA Takahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Aberrant DNA methylation of imprinted loci in sperm from infertile men and the causal mechanism
- Principal Investigator
  
  ARIMA Takahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Epigenetics of Cdx2 gene on the extraembryonic cell lineage and human trophoblastic stem cell.
- Principal Investigator
  
  SUGAWARA Junichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
The cell determination to extraembryonic tissue and the human placental stem cell.
- Principal Investigator
  
  ARIMA Takahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University

[Book] トロホブラスト幹細胞と展開2021
- Author(s)
  小林枝里、岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PLANNED-19H05757
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PLANNED-19H05757
[Book] トロホブラスト幹細胞と展開2021
- Author(s)
  小林枝里、岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21H03072
[Book] ヒト胎盤発生と幹細胞2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Total Pages
  5
- Publisher
  医学書院(金原出版）
- Data Source
  KAKENHI-PROJECT-21H03072
[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21H03072
[Book] ヒト初期発生におけるエピジェネティクス2021
- Author(s)
  岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21H03072
[Book] ヒト初期発生におけるエピジェネティクス2021
- Author(s)
  岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-19H05757
[Book] ヒト胎盤発生と幹細胞2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Total Pages
  5
- Publisher
  医学書院(金原出版）
- Data Source
  KAKENHI-PLANNED-19H05757
[Book] プラダー・ウィリ症候群2019
- Author(s)
  岡江寛明, 有馬隆博.
- Total Pages
  1
- Publisher
  雑誌診断と治療社
- Data Source
  KAKENHI-PROJECT-18K09216
[Book] プラダー・ウィリ症候群2019
- Author(s)
  岡江寛明, 有馬隆博
- Total Pages
  1
- Publisher
  雑誌診断と治療社
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] 加齢によるエピジェネティクス変異2019
- Author(s)
  服部裕充、小林記緒、岡江寛明、有馬隆博
- Total Pages
  7
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-18K09216
[Book] 加齢によるエピジェネティクス変異2019
- Author(s)
  服部裕充、小林記緒、岡江寛明、有馬隆博
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] 胎盤の遺伝子工学的応用（perinatal stem cell）2019
- Author(s)
  樋浦仁,岡江寛明, 有馬隆博
- Total Pages
  1
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] プラダー・ウィリ症候群.2019
- Author(s)
  岡江寛明, 有馬隆博.
- Total Pages
  1
- Publisher
  雑誌診断と治療社
- Data Source
  KAKENHI-PROJECT-18K09216
[Book] Epigenetics in Human Disease, Second Edition2018
- Author(s)
  Hiura H, Hattori H, Kobayashi N, Takahashi S, Okae H, Arima T
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] Therapeutic approaches to imprinting diseases. Epigenetics in Human Disease,2018
- Author(s)
  Hattori H, Hiura H, Kobayashi N, Takahashi S, Okae H, Arima T.
- Total Pages
  6
- Publisher
  Academic Press.
- Data Source
  KAKENHI-PROJECT-18K09216
[Book] Epigenetics in Human Disease, Second Edition2018
- Author(s)
  Hiura H, Hattori H, Kobayashi N, Takahashi S, Okae H, Arima T
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-15K10657
[Book] ヒト栄養膜幹細胞の樹立.2018
- Author(s)
  岡江寛明, 有馬隆博.
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18K09216
[Book] 新着論文レビュー2018
- Author(s)
  岡江寛明、有馬隆博
- Publisher
  ライフサイエンス
- Data Source
  KAKENHI-PROJECT-15K10657
[Book] 実験医学2018
- Author(s)
  岡江寛明、有馬隆博
- Total Pages
  1430
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K10657
[Book] 新着論文レビュー2018
- Author(s)
  岡江寛明、有馬隆博
- Publisher
  ライフサイエンス
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] ヒト栄養膜幹細胞の樹立.2018
- Author(s)
  岡江寛明, 有馬隆博.
- Total Pages
  4
- Publisher
  羊土社.
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] 実験医学2018
- Author(s)
  岡江寛明、有馬隆博
- Total Pages
  1430
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] Therapeutic approaches to imprinting diseases. Epigenetics in Human Disease2018
- Author(s)
  Hattori H, Hiura H, Kobayashi N, Takahashi S, Okae H, Arima T.
- Total Pages
  6
- Publisher
  Academic Press.
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] Handbook of Nutrition, Diet, and Epigenetics2017
- Author(s)
  Miyauchi N, Kitamura A, Hiura H, Okae H, Kobayashi N, Hattori H, Takahashi S, Arima T
- Publisher
  Springer International Publishing
- Data Source
  KAKENHI-PROJECT-15K10657
[Book] 生殖補助医療(ART)　-胚培養の理論と実際-2017
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子
- Total Pages
  352
- Publisher
  近代出版
- Data Source
  KAKENHI-PROJECT-15K15592
[Book] 生殖補助医療(ART)　-胚培養の理論と実際-2017
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子
- Total Pages
  352
- Publisher
  近代出版
- Data Source
  KAKENHI-PROJECT-15K10657
[Book] 産科と婦人科842017
- Author(s)
  濱田裕貴, 岡江寛明, 有馬隆博
- Total Pages
  110
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] Epigenetic Alterations in Human Sperm. Handbook of Nutrition, Diet, and Epigenetics2017
- Author(s)
  Miyauchi N, Kitamura A, Hiura H, Okae H, Kobayashi N, Hattori H, Takahashi S, Arima T
- Publisher
  Springer International Publishing
- Data Source
  KAKENHI-PROJECT-17H04335
[Book] Pharma Medica2016
- Author(s)
  有馬隆博、宮内尚子、北村茜、樋浦仁、岡江寛明、千葉初音
- Total Pages
  144
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15K10657
[Book] Pharma Medica2016
- Author(s)
  有馬隆博、宮内尚子、北村茜、樋浦仁、岡江寛明、千葉初音
- Total Pages
  144
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15K15592
[Book] 臨床婦人科産科2014
- Author(s)
  濱田裕貴、岡江寛明、有馬隆博
- Total Pages
  8
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24613001
[Book] 臨床婦人科産科2014
- Author(s)
  濱田裕貴、岡江寛明、有馬隆博
- Total Pages
  184
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25670691
[Book] 臨床婦人科産科2014
- Author(s)
  濱田裕貴、岡江寛明、有馬隆博
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23390385
[Book] 遺伝子医学MOOK 25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24613001
[Book] 遺伝子医学MOOK 25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社　メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23390385
[Book] 臨床婦人科産科2013
- Author(s)
  濱田裕貴、岡江寛明、有馬隆博
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25670691
[Book] 遺伝子医学MOOK 25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23659768
[Book] 遺伝子医学MOOK25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24613001
[Book] 遺伝子医学MOOK25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23390385
[Book] 遺伝子医学MOOK 25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社メディカルドゥ(印刷中)
- Data Source
  KAKENHI-PUBLICLY-23013003
[Book] 遺伝子医学MOOK25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23659768
[Book] 遺伝子医学MOOK25号2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-25670691
[Book] DNA METHYLATION, Aberrant DNA methylation of imprinted loci in male and female germ cells of infertile couples2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-23390385
[Book] DNA METHYLATION2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C.
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-23659768
[Book] Aberrant DNA methylation of imprinted loci in male and female germ cells of infertilecouples2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C
- Publisher
  INTECH. DNA METHYLATION
- Data Source
  KAKENHI-PROJECT-23659768
[Book] DNA METHYLATION2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C.
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-24613001
[Book] DNA METHYLATION2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C.
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-23390385
[Book] DNA METHYLATION2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C.
- Publisher
  INTECH
- Data Source
  KAKENHI-PUBLICLY-23013003
[Book] 産婦人科の実際2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子、阿部千鶴、林千賀
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-23659768
[Book] 助産雑誌2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子
- Total Pages
  11
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23390385
[Book] 癌と化学療法2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、宮内尚子、佐藤芙美
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-23390385
[Book] 卵子学2011
- Author(s)
  有馬隆博, 樋浦仁, 岡江寛明, 佐藤晶子, 宮内尚子
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-23390385
[Book] 卵子学2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-23659768
[Book] 産婦人科の実際2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子、阿部千鶴、林千賀
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-23390385
[Book] 助産雑誌2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23659768
[Book] 癌と化学療法2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、宮内尚子、佐藤芙美
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-23659768
[Book] 卵子学2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-23390385
[Journal Article] Modeling embryo-endometrial interface recapitulating human embryo implantation2024
- Author(s)
  Shibata Shun、Endo Shun、Nagai Luis A. E.、H. Kobayashi Eri、Oike Akira、Kobayashi Norio、Kitamura Akane、Hori Takeshi、Nashimoto Yuji、Nakato Ryuichiro、Hamada Hirotaka、Kaji Hirokazu、Kikutake Chie、Suyama Mikita、Saito Masatoshi、Yaegashi Nobuo、Okae Hiroaki、Arima Takahiro
- Journal Title
  
  Science Advances
  
  Volume: 10 Issue: 8
- DOI
  10.1126/sciadv.adi4819
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21H03803, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
[Journal Article] Trophoblast stem cell-based organoid models of the human placental barrier2024
- Author(s)
  Hori Takeshi、Okae Hiroaki、Shibata Shun、Kobayashi Norio、Kobayashi Eri H.、Oike Akira、Sekiya Asato、Arima Takahiro、Kaji Hirokazu
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41467-024-45279-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
[Journal Article] Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape2023
- Author(s)
  Varberg Kaela M.、Dominguez Esteban M.、Koseva Boryana、Varberg Joseph M.、McNally Ross P.、Moreno-Irusta Ayelen、Wesley Emily R.、Iqbal Khursheed、Cheung Warren A.、Schwendinger-Schreck Carl、Smail Craig、Okae Hiroaki、Arima Takahiro、Lydic Michael、Holoch Kristin、Marsh Courtney、Soares Michael J.、Grundberg Elin
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 4826-4826
- DOI
  10.1038/s41467-023-40424-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] Regulation of human trophoblast gene expression by endogenous retroviruses2023
- Author(s)
  Frost Jennifer M.、Amante Samuele M.、Okae Hiroaki、Jones Eleri M.、Ashley Brogan、Lewis Rohan M.、Cleal Jane K.、Caley Matthew P.、Arima Takahiro、Maffucci Tania、Branco Miguel R.
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: - Issue: 4 Pages: 527-538
- DOI
  10.1038/s41594-023-00960-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] CITED2 is a conserved regulator of the uterine-placental interface.2023
- Author(s)
  Kuna Marija、Dhakal Pramod、Iqbal Khursheed、Dominguez Esteban M.、Kent Lindsey N.、Muto Masanaga、Moreno-Irusta Ayelen、Kozai Keisuke、Varberg Kaela M.、Okae Hiroaki、Arima Takahiro、Sucov Henry M.、Soares Michael J.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 3 Pages: 120-123
- DOI
  10.1073/pnas.2213622120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-20K15699, KAKENHI-PLANNED-19H05757
[Journal Article] CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development2023
- Author(s)
  Takanori Shimizu*, Akira Oike*, Eri H. Kobayashi*, Asato Sekiya, Norio Kobayashi, Shun Shibata, Hirotaka Hamada, Masatoshi Saito, Nobuo Yaegashi, Mikita Suyama, Takahiro Arima, and Hiroaki Okae. *T.S., A.O., and E.H.K. contributed equally to this work.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 51
- DOI
  10.1073/pnas.2311372120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08838, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] Genomic imprinting in human placentation2022
- Author(s)
  Kobayashi Eri H.、Shibata Shun、Oike Akira、Kobayashi Norio、Hamada Hirotaka、Okae Hiroaki、Arima Takahiro
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 21 Issue: 1
- DOI
  10.1002/rmb2.12490
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022
- Author(s)
  Kobayashi Norio、Okae Hiroaki、Hiura Hitoshi、Kubota Naoto、Kobayashi Eri H.、Shibata Shun、Oike Akira、Hori Takeshi、Kikutake Chie、Hamada Hirotaka、Kaji Hirokazu、Suyama Mikita、Bortolin-Cavaill? Marie-Line、Cavaill? J?r?me、Arima Takahiro
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 3071-3071
- DOI
  10.1038/s41467-022-30775-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-22K15117, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05757
[Journal Article] The multifaceted role of GCM1 during trophoblast differentiation in the human placenta2022
- Author(s)
  Jeyarajah Mariyan J.、Jaju Bhattad Gargi、Kelly Rachel D.、Baines Kelly J.、Jaremek Adam、Yang Fei-Hung P.、Okae Hiroaki、Arima Takahiro、Dumeaux Vanessa、Renaud Stephen J.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 49
- DOI
  10.1073/pnas.2203071119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PLANNED-19H05757
[Journal Article] Intersection of regulatory pathways controlling hemostasis and hemochorial placentation2021
- Author(s)
  Muto Masanaga、Chakraborty Damayanti、Varberg Kaela M.、Moreno-Irusta Ayelen、Iqbal Khursheed、Scott Regan L.、McNally Ross P.、Choudhury Ruhul H.、Aplin John D.、Okae Hiroaki、Arima Takahiro、Matsumoto Shoma、Ema Masatsugu、Mast Alan E.、Grundberg Elin、Soares Michael J.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 50
- DOI
  10.1073/pnas.2111267118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-20K15699
[Journal Article] ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development2021
- Author(s)
  Varberg Kaela M.、Iqbal Khursheed、Muto Masanaga、Simon Mikaela E.、Scott Regan L.、Kozai Keisuke、Choudhury Ruhul H.、Aplin John D.、Biswell Rebecca、Gibson Margaret、Okae Hiroaki、Arima Takahiro、Vivian Jay L.、Grundberg Elin、Soares Michael J.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 10
- DOI
  10.1073/pnas.2016517118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-20K15699
[Journal Article] Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts2020
- Author(s)
  Jaju Bhattad Gargi、Jeyarajah Mariyan J.、McGill Megan G.、Dumeaux Vanessa、Okae Hiroaki、Arima Takahiro、Lajoie Patrick、B?rub? Nathalie G.、Renaud Stephen J.
- Journal Title
  
  Cell Death & Disease
  
  Volume: 11 Issue: 5 Pages: 311-327
- DOI
  10.1038/s41419-020-2500-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
[Journal Article] Unique features and emerging in vitro models of human placental development.2020
- Author(s)
  Shun Shibata, Eri H Kobayashi, Norio Kobayashi, Akira Oike, Hiroaki Okae, Takahiro Arima.
- Journal Title
  
  Reprod Med Biol .
  
  Volume: 12 Issue: 4 Pages: 301-313
- DOI
  10.1002/rmb2.12347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16135, KAKENHI-PROJECT-20K22615, KAKENHI-PROJECT-20K22943, KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
[Journal Article] G protein subunit β1 is an important mediator of the late stage of endochondral ossification2020
- Author(s)
  Ruengsinpinya Lerdluck、Murakami Tomohiko、Nakamura Eriko、Takahata Yoshifumi、Hata Kenji、Nakaminami Yuri、Okae Hiroaki、Nishimura Riko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 533 Issue: 1 Pages: 90-96
- DOI
  10.1016/j.bbrc.2020.08.119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-19H03824, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19K22708
[Journal Article] Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal?fetal exchange interface2020
- Author(s)
  Bhattacharya Bhaswati、Home Pratik、Ganguly Avishek、Ray Soma、Ghosh Ananya、Islam Md. Rashedul、French Valerie、Marsh Courtney、Gunewardena Sumedha、Okae Hiroaki、Arima Takahiro、Paul Soumen
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 25 Pages: 14280-14291
- DOI
  10.1073/pnas.1920201117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
[Journal Article] Naive Human Embryonic Stem Cells Can Give Rise to Cells with a Trophoblast-like Transcriptome and Methylome2020
- Author(s)
  Cinkornpumin Jessica K.、Kwon Sin Young、Guo Yixin、Hossain Ishtiaque、Sirois Jacinthe、Russett Colleen S.、Tseng Hsin-Wei、Okae Hiroaki、Arima Takahiro、Duchaine Thomas F.、Liu Wanlu、Pastor William A.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 15 Issue: 1 Pages: 198-213
- DOI
  10.1016/j.stemcr.2020.06.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
[Journal Article] Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells2020
- Author(s)
  Castel G, Meistermann D, Bretin B, Firmin J, Blin J, Loubersac S, Bruneau A, Chevolleau S, Kilens S, Chariau C, Gaignerie A, Francheteau Q, Kagawa H, Charpentier E, Flippe L, Francois-Campion V, Haider S, Dietrich B, Knofler M, Arima T, Bourdon J, Rivron N, Masson D, Fournier T, Okae H, Freour T, David L
- Journal Title
  
  Cell Reports
  
  Volume: 33 Issue: 8 Pages: 108419-108419
- DOI
  10.1016/j.celrep.2020.108419
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-18K09216
[Journal Article] Cutting Edge: G Protein Subunit b 1 Negatively Regulates NLRP3 Inflammasome Activation2019
- Author(s)
  Tomohiko Murakami, Lerdluck Ruengsinpinya, Eriko Nakamura,Yoshifumi Takahata, Kenji Hata, Hiroaki Okae,Shun’ichiro Taniguchi, Masafumi Takahashi and Riko Nishimura
- Journal Title
  
  The Journal of Immunology
  
  Volume: 202 Issue: 7 Pages: 1942-1947
- DOI
  10.4049/jimmunol.1801388
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K19640, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19H03824
[Journal Article] Association of four imprinting disorders and ART.2019
- Author(s)
  Hattori H, Hiura H, Kitamura A, Miyauchi N, Kobayashi N, Takahashi S, Okae H, Kyono K, Kagami M, Ogata T, Arima T.
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 11 Pages: 21-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09216
[Journal Article] Association of four imprinting disorders and ART2019
- Author(s)
  Hattori H, Hiura H, Kitamura A, Miyauchi N, Kobayashi N, Takahashi S, Okae H, Kyono K, Kagami M, Ogata T, Arima T.
- Journal Title
  
  Clin Epigenetics
  
  Volume: 11 Issue: 1 Pages: 21-21
- DOI
  10.1186/s13148-019-0623-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02355, KAKENHI-PROJECT-17K09188, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19K16135, KAKENHI-PROJECT-19K18660, KAKENHI-PROJECT-17H04204
[Journal Article] Loss of p57KIP2expression confers resistance to contact inhibition in human androgenetic trophoblast stem cells2019
- Author(s)
  Takahashi Sota、Okae Hiroaki、Kobayashi Norio、Kitamura Akane、Kumada Kanako、Yaegashi Nobuo、Arima Takahiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 52 Pages: 26606-26613
- DOI
  10.1073/pnas.1916019116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19K16135, KAKENHI-PROJECT-19K18660, KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-17H04335
[Journal Article] Association of four imprinting disorders and ART.2019
- Author(s)
  Hattori H, Hiura H, Kitamura A, Miyauchi N, Kobayashi N, Takahashi S, Okae H, Kyono K, Kagami M, Ogata T, Arima T.
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 11 Pages: 21-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04335
[Journal Article] Lactate Dehydrogenase C Is Required for the protein Expression of a Sperm-specific Isoform of Lactate Dehydrogenase A.2019
- Author(s)
  Dodo M, Kitamura H, Shima H, Wati S, Ota N, Chiba H, Okae H, Arima T, Igarashi K, Koseki H, Sekine H, Motohashi H.
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 印刷中
- NAID
  40021893390
- Open Access
- Data Source
  KAKENHI-PROJECT-17H04335
[Journal Article] Derivation of Human Trophoblast Stem Cells2018
- Author(s)
  Okae Hiroaki、Toh Hidehiro、Sato Tetsuya、Hiura Hitoshi、Takahashi Sota、Shirane Kenjiro、Kabayama Yuka、Suyama Mikita、Sasaki Hiroyuki、Arima Takahiro
- Journal Title
  
  Cell Stem Cell
  
  Volume: 22 Issue: 1 Pages: 50-63.e6
- DOI
  10.1016/j.stem.2017.11.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19709, KAKENHI-PROJECT-17H04335, KAKENHI-PROJECT-15K10657
[Journal Article] Derivation of Human Trophoblast Stem Cells.2018
- Author(s)
  Okae H, Toh H, Sato T, Hiura H, Takahashi S, Shirane K, Kabayama Y, Suyama M, Sasaki H, Arima T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 22 Pages: 50-63
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04335
[Journal Article] Derivation of Human Trophoblast Stem Cells.2018
- Author(s)
  Okae H, Toh H, Sato T, Hiura H, Takahashi S, Shirane K, Kabayama Y, Suyama M, Sasaki H, Arima T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 22 Pages: 50-63
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09216
[Journal Article] Factors associated with aberrant imprint methylation and oligozoospermia2017
- Author(s)
  Kobayashi N, Miyauchi N, Tatsuta N, Kitamura A, Okae H, Hiura H, Sato A, Utsunomiya T, Yaegashi N, Nakai K, Arima T
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 42336-42336
- DOI
  10.1038/srep42336
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15592, KAKENHI-PROJECT-26870032, KAKENHI-PROJECT-26870033, KAKENHI-PROJECT-15K10657, KAKENHI-PROJECT-15K20121, KAKENHI-ORGANIZER-25112001
[Journal Article] Genome-wide microRNA expression profiling in placentae from frozen-thawed blastocyst transfer2017
- Author(s)
  Hiura Hitoshi、Hattori Hiromitsu、Kobayashi Norio、Okae Hiroaki、Chiba Hatsune、Miyauchi Naoko、Kitamura Akane、Kikuchi Hiroyuki、Yoshida Hiroaki、Arima Takahiro
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 9 Issue: 1
- DOI
  10.1186/s13148-017-0379-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19709, KAKENHI-PROJECT-15K20121, KAKENHI-PROJECT-17H04335, KAKENHI-PROJECT-17H06529, KAKENHI-PROJECT-15K10657
[Journal Article] Transcriptomic signature of the follicular somatic compartment surrounding an oocyte with high developmental competence2017
- Author(s)
  Sugimura Satoshi、Kobayashi Norio、Okae Hiroaki、Yamanouchi Tadayuki、Matsuda Hideo、Kojima Takumi、Yajima Akira、Hashiyada Yutaka、Kaneda Masahiro、Sato Kan、Imai Kei、Tanemura Kentaro、Arima Takahiro、Gilchrist Robert B.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 6815-6815
- DOI
  10.1038/s41598-017-07039-5
- NAID
  120006711707
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19709, KAKENHI-PROJECT-17H04335, KAKENHI-PROJECT-17H06529, KAKENHI-PROJECT-15K18768
[Journal Article] DNA methylation dynamics during early human development2016
- Author(s)
  Okae H, Arima T
- Journal Title
  
  Journal of Mammalian Ova Research
  
  Volume: 33 Issue: 2 Pages: 101-107
- DOI
  10.1274/jmor.33.101
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10657
[Journal Article] Allele-specific methylome and transcriptome analysis reveals widespread imprinting in the human placenta2016
- Author(s)
  Hamada, H., Okae, H., Toh, H., Chiba, H., Hiura, H., Shirane, K., Sato, T., Suyama, M., Yaegashi, N., Sasaki, H. & Arima
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: 99 Issue: 5 Pages: 1045-1058
- DOI
  10.1016/j.ajhg.2016.08.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J04310, KAKENHI-PROJECT-15K15592, KAKENHI-PROJECT-26870033, KAKENHI-PROJECT-15K10657, KAKENHI-ORGANIZER-25112001
[Journal Article] DNA methylation dynamics during early human development2016
- Author(s)
  Okae H, Arima T
- Journal Title
  
  Journal of Mammalian Ova Research
  
  Volume: 33 Pages: 2-2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15592
[Journal Article] Genome-Scale Assessment of Age-Related DNA Methylation Changes in Mouse Spermatozoa.2016
- Author(s)
  Kobayashi N, Okae H, Hiura H, Chiba H, Shirakata Y, Hara K, Tanemura K, Arima T.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 11 Pages: e0167127-e0167127
- DOI
  10.1371/journal.pone.0167127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01523, KAKENHI-PLANNED-25114004, KAKENHI-PROJECT-26450453, KAKENHI-PROJECT-15K15592, KAKENHI-PROJECT-26870033, KAKENHI-PROJECT-15K10657, KAKENHI-ORGANIZER-25112001
[Journal Article] DNA methylation errors in imprinting disorders and male infertility.2015
- Author(s)
  Kitamura A, Hiura H, Miyauchi N, Okae H, Chiba H, Arima T.
- Journal Title
  
  Congenit Anom (Kyoto)
  
  Volume: 55 Pages: 133-144
- Data Source
  KAKENHI-PROJECT-15K10657
[Journal Article] DNA methylation errors in imprinting disorders and male infertility.2015
- Author(s)
  Kitamura A, Hiura H, Miyauchi N, Okae H, Chiba H, Arima T.
- Journal Title
  
  Congenit Anom (Kyoto).
  
  Volume: 55 Pages: 133-144
- Data Source
  KAKENHI-PUBLICLY-26112502
[Journal Article] DNA methylation errors in imprinting disorders and male infertility.2015
- Author(s)
  Kitamura A, Hiura H, Miyauchi N, Okae H, Chiba H, Arima T.
- Journal Title
  
  Congenit Anom (Kyoto)
  
  Volume: 55 Pages: 133-144
- Data Source
  KAKENHI-PROJECT-15K15592
[Journal Article] Imprinting methylation errors in ART.2014
- Author(s)
  Hiura H, Okae H, Chiba H, Miyauchi N, Sato F, Sato A, Arima T.
- Journal Title
  
  Reproductive Medicine and Biology.
  
  Volume: 13 Pages: 193-202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670691
[Journal Article] RNA sequencing-based identification of aberrant imprinting in cloned mice.2014
- Author(s)
  Okae H, Matoba S, Nagashima T, Mizutani E, Inoue K, Ogonuki N, Chiba H, Funayama R, Tanaka S, Yaegashi N, Nakayama K, Sasaki H, Ogura A, Arima T.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 Pages: 992-1001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26112502
[Journal Article] Imprinting methylation errors in ART.2014
- Author(s)
  Hiura H, Okae H, Chiba H, Miyauchi N, Sato F, Sato A, Arima T.
- Journal Title
  
  Reproductive Medicine and Biology.
  
  Volume: 13 Pages: 193-202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24613001
[Journal Article] RNA sequencing-based identification of aberrant imprinting in cloned mice.2014
- Author(s)
  Okae H, Matoba S, Nagashima T, Mizutani E, Inoue K, Ogonuki N, Chiba H, Funayama R, Tanaka S, Yaegashi N, Nakayama K, Sasaki H, Ogura A, Arima T.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 Issue: 4 Pages: 992-1001
- DOI
  10.1093/hmg/ddt495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23500507, KAKENHI-PUBLICLY-24116503, KAKENHI-PROJECT-24700951, KAKENHI-PROJECT-24780277, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112009, KAKENHI-PLANNED-25112010
[Journal Article] Genome-wide analysis of DNA methylation dynamics during early human development.2014
- Author(s)
  Okae H, Chiba H, Hiura H, Hamada H, Sato A, Utsunomiya T, Kikuchi H, Yoshida H, Tanaka A, Suyama M, Arima T.
- Journal Title
  
  PLOS Genetics
  
  Volume: 10
- Data Source
  KAKENHI-PROJECT-25670691
[Journal Article] RNA sequencing-based identification of aberrant imprinting in cloned mice.2014
- Author(s)
  Okae H, Matoba S, Nagashima T, Mizutani E, Inoue K, Ogonuki N, Chiba H, Funayama R, Tanaka S, Yaegashi N, Nakayama K, Sasaki H, Ogura A, Arima T.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 Pages: 992-1001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24613001
[Journal Article] RNA sequencing-based identification of aberrant imprinting in cloned mice.2014
- Author(s)
  Okae H, Matoba S, Nagashima T, Mizutani E, Inoue K, Ogonuki N, Chiba H, Funayama R, Tanaka S, Yaegashi N, Nakayama K, Sasaki H, Ogura A, Arima T.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 Pages: 992-1001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670691
[Journal Article] Genome-wide analysis of DNA methylation dynamics during early human development2014
- Author(s)
  Okae H, Chiba H, Hiura H, Hamada H, Sato A, Utsunomiya T, Kikuchi H, Yoshida H, Tanaka A, Suyama M, Arima T.
- Journal Title
  
  PLOS Genetics
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24613001
[Journal Article] Genome-wide analysis of DNA methylation dynamics during early human development.2014
- Author(s)
  Okae H, Chiba H, Hiura H, Hamada H, Sato A, Utsunomiya T, Kikuchi H, Yoshida H, Tanaka A, Suyama M, Arima T.
- Journal Title
  
  PLOS Genetics.
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26112502
[Journal Article] ヒト生殖補助医療（ART）とエピジェネティクスの異常2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Journal Title
  
  遺伝子医学MOOK（メディカルドゥ）
  
  Volume: 25 Pages: 178-183
- Data Source
  KAKENHI-PROJECT-23592390
[Journal Article] ヒト生殖補助医療(ART)とエピジェネティクスの異常2013
- Author(s)
  千葉初音、岡江寛明、有馬隆博
- Journal Title
  
  遺伝子医学MOOK(メディカルドゥ)
  
  Volume: 25 Pages: 178-183
- Data Source
  KAKENHI-PROJECT-23592390
[Journal Article] DNA methylation errors in imprinting disorders and assisted reproductive technologies.2013
- Author(s)
  Chiba H, Hiura H, Okae H, Miyauchi N, Sato F, Sato A, Arima T.
- Journal Title
  
  Pediatrics international.
  
  Volume: 55 Issue: 5 Pages: 542-549
- DOI
  10.1111/ped.12185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23592390, KAKENHI-PROJECT-23710223, KAKENHI-PROJECT-23791799, KAKENHI-PROJECT-24613001, KAKENHI-PROJECT-25670691
[Journal Article] Stability of the abnormal imprinting of human induced pluripotent stem cells2013
- Author(s)
  Hiura H, Toyoda M, Okae H, Sakurai M, Miyauchi N, Sato A, Kiyokawa N, Okita H, Miyagawa Y, Akutsu H, Nishino K, Umezawa A, Arima T
- Journal Title
  
  BMC Genetics
  
  Volume: 14 Issue: 1 Pages: 32-32
- DOI
  10.1186/1471-2156-14-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23710223, KAKENHI-PROJECT-23791799, KAKENHI-PROJECT-24613001, KAKENHI-PROJECT-25670691
[Journal Article] ヒト生殖補助医療(ART) とエピジェネティクスの異常2013
- Author(s)
  千葉初音, 岡江寛明, 有馬隆博
- Journal Title
  
  遺伝子医学
  
  Volume: MOOK25号 Pages: 178-183
- URL
  http://www.bioweb.ne.jp/content/idensi/idensi_mook0025.html
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390385
[Journal Article] 生殖補助医療由来の先天性ゲノムインプリンティング異常症2012
- Author(s)
  有馬隆博、樋浦仁、岡江寛明
- Journal Title
  
  日本生殖内分泌学会雑誌 Japanese Journal of Reproductive Endocrinology
  
  Volume: 17 Pages: 54-58
- NAID
  40019434316
- Data Source
  KAKENHI-PUBLICLY-23013003
[Journal Article] 生殖補助医療由来の先天性ゲノムインプリンティング異常症2012
- Author(s)
  有馬隆博、樋浦仁、岡江寛明
- Journal Title
  
  日本生殖内分泌学会雑誌 Japanese Journal of Reproductive Endocrinology
  
  Volume: 17 Pages: 54-58
- NAID
  40019434316
- Data Source
  KAKENHI-PROJECT-24613001
[Journal Article] 生殖補助医療由来の先天性ゲノムインプリンティング異常症2012
- Author(s)
  有馬隆博、樋浦仁、岡江寛明
- Journal Title
  
  日本生殖内分泌学会雑誌 Japanese Journal of Reproductive Endocrinology
  
  Volume: 17 Pages: 54-58
- NAID
  40019434316
- Data Source
  KAKENHI-PROJECT-23659768
[Journal Article] 生殖補助医療由来の先天性ゲノムインプリンティング異常症2012
- Author(s)
  有馬隆博、樋浦仁、岡江寛明
- Journal Title
  
  日本生殖内分泌学会雑誌 Japanese Journal of Reproductive Endocrinology
  
  Volume: 17 Pages: 54-58
- NAID
  40019434316
- Data Source
  KAKENHI-PROJECT-23390385
[Journal Article] Characterization of DNA methylation errors in patients with imprinting disorders conceived by assisted reproductive technologies.2012
- Author(s)
  Hiura H, Okae H, Miyauchi N, Sato F, Sato A , Van De Pette M, John R M, Kagami M, Nakai K, Soejima H, Ogata T, Arima T.
- Journal Title
  
  Human Reproduction
  
  Volume: 27(8) Issue: 8 Pages: 2541-2548
- DOI
  10.1093/humrep/des197
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23013003, KAKENHI-PROJECT-23390083, KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23659768, KAKENHI-PROJECT-23710223, KAKENHI-PROJECT-23791799, KAKENHI-PROJECT-24613001
[Journal Article] High-throughput detection of imprint methylation errors in the ovarian cancer by the bisulphite PCR-Luminex method2012
- Author(s)
  Hiura H, Okae H, Kobayashi H, Miyauchi N, Sato F, Sato A, Suzuki F, Nagase S, Junichi Sugawara J, Nakai K, Yaegashi N, Arima T
- Journal Title
  
  BMC medical Genomics
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390385
[Journal Article] Aberrant DNA Methylation of Imprinted Loci2012
- Author(s)
  Arima T, Okae H, Hiura H, Hayashi C et al
- Journal Title
  
  INTECH
  
  Volume: 29 Pages: 183-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659768
[Journal Article] Aberrant DNA Methylation of Imprinted Loci in Male and Female Germ Cells of Infertile Couples2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C
- Journal Title
  
  INTECH
  
  Volume: 29 Pages: 183-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390385
[Journal Article] JapaneseJournal of Reproductive Endocrinology「生殖補助医療由来の先天性ゲノムインプリンティング異常症」2012
- Author(s)
  有馬隆博、樋浦仁、岡江寛明
- Journal Title
  
  日本生殖内分泌学会雑誌
  
  Volume: 17 Pages: 54-58
- Data Source
  KAKENHI-PROJECT-23659768
[Journal Article] Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression2012
- Author(s)
  Hiroaki Okae, et al
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 21 Issue: 3 Pages: 548-558
- DOI
  10.1093/hmg/ddr488
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062003, KAKENHI-PLANNED-20062010, KAKENHI-PUBLICLY-23013003, KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23659768, KAKENHI-PROJECT-23710223, KAKENHI-PROJECT-24613001
[Journal Article] High-throughput detection of imprint methylation errors in the ovarian cancer by the bisulphite PCR-Luminex method2012
- Author(s)
  Hiura H, Okae H, Kobayashi H, Miyauchi N, Sato F, Sato A, Suzuki F, Nagase S, Junichi Sugawara J, Nakai K, Yaegashi N, Arima T
- Journal Title
  
  BMC medical Genomics
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23013003
[Journal Article] High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method.2012
- Author(s)
  Hiura H, Okae H, Kobayashi H, Miyauchi N, Sato F, Sato A, Suzuki F, Nagase S, Sugawara J, Nakai K, Yaegashi N, Arima T.
- Journal Title
  
  BMC Medical Genomics
  
  Volume: 5 Issue: 1 Pages: 8-17
- DOI
  10.1186/1755-8794-5-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23013003, KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23659768, KAKENHI-PROJECT-23710223, KAKENHI-PROJECT-23791799, KAKENHI-PROJECT-24613001
[Journal Article] Aberrant DNA Methylation of Imprinted Loci in Male and Female Germ Cells of Infertile Couples2012
- Author(s)
  Arima T, Okae H, Hiura H, Miyauchi N, Sato F, Sato A, Hayashi C
- Journal Title
  
  INTECH
  
  Volume: 29 Pages: 183-192
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23013003
[Journal Article] ART におけるエピジェティクス異常産婦人科の実際2011
- Author(s)
  有馬隆博, 樋浦仁, 岡江寛明, 佐藤晶子, 宮内尚子, 阿部千鶴, 林千賀
- Journal Title
  
  金原出版株式会社
  
  Pages: 741-750
- URL
  http://search.jamas.or.jp/link/ui/2011191627
- Data Source
  KAKENHI-PROJECT-23390385
[Journal Article] 母子の健康と環境影響助産雑誌2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子
- Journal Title
  
  医学書院
  
  Volume: 62 Pages: 11-11
- URL
  http://www.medbook.jp/eshopdo/refer/refer.php?sid=ns13533&cid=37&scid=211&mcid=&me=&vmode=&view_id=665-65-11&PHPSESSID=95fa583906e9fda3b226b39bc36e7518
- Data Source
  KAKENHI-PROJECT-23659768
[Journal Article] ARTにおけるエピジェティクス異常産婦人科の実際2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、佐藤晶子、宮内尚子、阿部千鶴、林千賀
- Journal Title
  
  金原出版株式会社
  
  Pages: 741-750
- URL
  http://search.jamas.or.jp/link/ui/2011191627
- Data Source
  KAKENHI-PROJECT-23659768
[Journal Article] ゲノムインプリンティングと発がん癌と化学療法2011
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、宮内尚子、佐藤芙美
- Journal Title
  
  癌と化学療法社
  
  Pages: 1745-1749
- URL
  http://www.pieronline.jp/content/article/0385-0684/38110/1745
- Data Source
  KAKENHI-PROJECT-23659768
[Journal Article] Assessing loss of imprint methylation in sperm from subfertile men using novel methylation polymerase chain reaction Luminex analysis2011
- Author(s)
  Sato A, Hiura H, Okae H, Miyauchi N, Abe Y, Utsunomiya T, Yaegashi N, Arima T
- Journal Title
  
  Fertil and Steril
  
  Volume: 95 Pages: 129-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659768
[Journal Article] Assessing loss of imprint methylation in sperm from subfertile men using novel methylation PCR-Luminex analysis2011
- Author(s)
  Sato A, Hiura H, Okae H, Miyauchi N, Abe Y, Utsunomiya T, Yaegashi N, Arima T
- Journal Title
  
  Fertil and Steril
  
  Volume: 95 Issue: 1 Pages: 129-134
- DOI
  10.1016/j.fertnstert.2010.06.076
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23013003, KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23659768, KAKENHI-PROJECT-23710223, KAKENHI-PROJECT-23791799
[Presentation] ヒト栄養膜幹細胞を用いた胎盤研究2024
- Author(s)
  岡江寛明
- Organizer
  第４回　有性生殖学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] ヒト栄養膜幹細胞を用いた胎盤研究2024
- Author(s)
  岡江寛明
- Organizer
  第４回　有性生殖学会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Unlocking the mysteries of pregnancy with stem cells2023
- Author(s)
  岡江寛明
- Organizer
  熊本大学発生医学研究所セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] C19MC confers differentiation potential into trophoblast lineages upon human PSCs2023
- Author(s)
  岡江寛明
- Organizer
  熊本大学発生医学研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] ヒトとマウス胎盤の対応関係の理解2023
- Author(s)
  岡江寛明
- Organizer
  新学術・全能性第5回公開シンポジウム
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] Disease modeling with human trophoblast stem cells2023
- Author(s)
  岡江寛明
- Organizer
  The 18th International Symposium of the Institute Network for Biomedical Sciences
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Disease modeling with human trophoblast stem cells2023
- Author(s)
  岡江寛明
- Organizer
  The 18th International Symposium of the Institute Network for Biomedical Sciences
- Invited
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] 遺伝子からひも解くヒトとマウス胎盤の対応関係2023
- Author(s)
  岡江寛明
- Organizer
  第68回日本生殖医学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human PSCs2023
- Author(s)
  岡江寛明
- Organizer
  IRCMS seminar "New Horizons in Developmental Biology"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] ヒトとマウス胎盤の対応関係の理解2023
- Author(s)
  岡江寛明
- Organizer
  新学術・全能性第5回公開シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] 遺伝子機能にもとづくヒトとマウス胎盤の進化的対応関係の理解2023
- Author(s)
  岡江寛明
- Organizer
  第41回日本受精着床学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] 遺伝子からひも解くヒトとマウス胎盤の対応関係2023
- Author(s)
  岡江寛明
- Organizer
  第68回日本生殖医学会学術講演会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] C19MC confers differentiation potential into trophoblast lineages upon human PSCs2023
- Author(s)
  岡江寛明
- Organizer
  熊本大学発生医学研究所セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] 遺伝子機能にもとづくヒトとマウス胎盤の進化的対応関係の理解2023
- Author(s)
  岡江寛明
- Organizer
  第41回日本受精着床学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Unlocking the mysteries of pregnancy with stem cells2023
- Author(s)
  岡江寛明
- Organizer
  熊本大学発生医学研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human PSCs2023
- Author(s)
  岡江寛明
- Organizer
  IRCMS seminar "New Horizons in Developmental Biology"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] Critical role of genomic imprinting in human placental development2022
- Author(s)
  岡江寛明
- Organizer
  新学術・全能性 The International Symposium “Totipotency and Germ Cell Development”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] C19MC is essential for the differentiation potential of hPSCs into trophoblast lineages2022
- Author(s)
  岡江寛明
- Organizer
  The 55th annual meeting of the Japanese Society of Developmental Biologists
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Critical role of genomic imprinting in human placental development2022
- Author(s)
  岡江寛明
- Organizer
  新学術・全能性 The International Symposium “Totipotency and Germ Cell Development”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] C19MC is essential for the differentiation potential of hPSCs into trophoblast lineages2022
- Author(s)
  岡江寛明
- Organizer
  The 55th annual meeting of the Japanese Society of Developmental Biologists
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Organizer
  ART FORUM’21 生殖の分子機構への新たなアプローチ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Modeling human placental development and disease with stem cells2021
- Author(s)
  岡江寛明
- Organizer
  第9回東北大学スマート・エイジング学際重点研究センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] ヒト胚着床モデル-母胎アセンブロイド-の開発2021
- Author(s)
  柴田峻、岡江寛明、有馬隆博
- Organizer
  ART FORUM’21 生殖の分子機構への新たなアプローチ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] ヒトES細胞からTS細胞への分化転換を阻害するエピジェネティックバリアの同定2021
- Author(s)
  岡江寛明
- Organizer
  AMED研究開発交流会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] 生殖医学研究の最前線　進歩し続ける基礎研究2021
- Author(s)
  岡江寛明、有馬隆博.
- Organizer
  66th生殖医学会学術講演会・総会：シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03072
[Presentation] ヒトES細胞からTS細胞への分化転換を阻害するエピジェネティックバリアの同定2021
- Author(s)
  岡江寛明
- Organizer
  AMED研究開発交流会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Modeling human placental development and disease with stem cells2021
- Author(s)
  岡江寛明
- Organizer
  第9回東北大学スマート・エイジング学際重点研究センターシンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] 生殖医学研究の最前線　進歩し続ける基礎研究2021
- Author(s)
  岡江寛明、有馬隆博.
- Organizer
  66th生殖医学会学術講演会・総会：シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] ヒトES細胞からTS細胞への運命転換2020
- Author(s)
  岡江寛明
- Organizer
  新学術領域研究「配偶子インテグリティの構築」「全能性プログラム」合同公開シンポジウム2020
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] 分化全能性の消失に関わるインプリント遺伝子の同定2020
- Author(s)
  岡江寛明、小林記緒、有馬隆博
- Organizer
  日本繁殖生物学会第113回大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Identification of an epigenetic barrier between human embryonic and trophoblast stem cells2020
- Author(s)
  岡江寛明
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] 分化全能性の消失に関わるインプリント遺伝子の同定2020
- Author(s)
  岡江寛明、小林記緒、有馬隆博
- Organizer
  日本繁殖生物学会第113回大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] Epigenetic restriction of human pluripotency by silencing of the chromosome 19 miRNA cluster2020
- Author(s)
  岡江寛明
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] ヒトES細胞からTS細胞への運命転換2020
- Author(s)
  岡江寛明
- Organizer
  新学術領域研究「配偶子インテグリティの構築」「全能性プログラム」合同公開シンポジウム2020
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] 着床前胚に由来する幹細胞を用いた全能性の再構築2020
- Author(s)
  岡江寛明
- Organizer
  新学術領域研究「全能性プログラム」Webinar
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] Identification of an epigenetic barrier between human embryonic and trophoblast stem cells2020
- Author(s)
  岡江寛明
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Epigenetic restriction of human pluripotency by silencing of the chromosome 19 miRNA cluster2020
- Author(s)
  岡江寛明
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] 着床前胚に由来する幹細胞を用いた全能性の再構築2020
- Author(s)
  岡江寛明
- Organizer
  新学術領域研究「全能性プログラム」Webinar
- Invited
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] ヒト胎盤幹（TS）細胞の樹立とその細胞特性2019
- Author(s)
  小林記緒、樋浦仁、岡江寛明、有馬隆博
- Organizer
  第14回日本生殖発生医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] 雄核発生胚に由来するヒトTS細胞の樹立2019
- Author(s)
  岡江　寛明
- Organizer
  新学術領域キックオフシンポジウム
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] 再生医療等に用いるヒト胎盤由来幹細胞の細胞特性の解明2019
- Author(s)
  岡江　寛明
- Organizer
  令和元年度AMED再生医療研究交流会
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] ヒト胚性幹細胞の栄養膜幹細胞への分化転換2019
- Author(s)
  小林記緒、岡江寛明,高橋聡太、樋浦仁、有馬隆博
- Organizer
  第42回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] Derivation of Human Trophoblast Stem Cells from Blastocysts and Villous Cytotrophoblast Cells.2019
- Author(s)
  Okae H. ArimaT.
- Organizer
  International Symposium on Epigenome 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] なぜ絨毛癌は稀なのか？ヒト栄養膜幹細胞を用いた胎盤の腫瘍化抑制機構の解析2019
- Author(s)
  岡江寛明, 高橋聡太、有馬隆博
- Organizer
  第42回日本分子生物学会年会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] Derivation of Human Trophoblast Stem Cells from Blastocysts and Villous Cytotrophoblast Cells.2019
- Author(s)
  Okae H. ArimaT.
- Organizer
  International Symposium on Epigenome 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] Disease modeling with human trophoblast stem cells2019
- Author(s)
  岡江　寛明
- Organizer
  幹細胞・再生医学イノベーション創出プログラム事業内交流会
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] Derivation of human trophoblast stem cells.2019
- Author(s)
  Okae H. ArimaT.
- Organizer
  The 35th Annual Meeting of ESHRE
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] なぜ絨毛癌は稀なのか？ヒト栄養膜幹細胞を用いた胎盤の腫瘍化抑制機構の解析2019
- Author(s)
  岡江　寛明
- Organizer
  第42回日本分子生物学会年会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05757
[Presentation] なぜ絨毛癌は稀なのか？ヒト栄養膜幹細胞を用いた胎盤の腫瘍化抑制機構の解析2019
- Author(s)
  岡江　寛明
- Organizer
  第42回日本分子生物学会年会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] ヒト胎盤幹（TS）細胞の樹立とその細胞特性2019
- Author(s)
  小林記緒、樋浦仁、岡江寛明、有馬隆博
- Organizer
  第14回日本生殖発生医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] Derivation of human trophoblast stem cells.2019
- Author(s)
  Okae H. ArimaT.
- Organizer
  Cold Spring Harbor Asia meeting on Stem Cell Crossroads.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] ヒト胎盤のトロフォブラスト幹細胞の樹立と臨床への応用2018
- Author(s)
  小林記緒、樋浦仁、岡江寛明、有馬隆博
- Organizer
  第70回日本産科婦人科学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] Derivation of human trophoblast stem cells.2018
- Author(s)
  Okae H. ArimaT.
- Organizer
  Cold Spring Harbor Asia meeting on Stem Cell Crossroads.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] Transposable element expression in placental development2018
- Author(s)
  Nehemiah S. Alvarez, Kesiuke Kozai, Damayanti Chakraborty, Khursheed Iqbal, Kaela M. Varberg, Pavla Brachova, Hiroaki Okae, Takahiro Arima, Gerald G. Schumann, Kathleen H. Burns and Michael J. Soares
- Organizer
  KEYSTONE SYMPOSIUM 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] Transposable element expression in placental development2018
- Author(s)
  Nehemiah S. Alvarez, Kesiuke Kozai, Damayanti Chakraborty, Khursheed Iqbal, Kaela M. Varberg, Pavla Brachova, Hiroaki Okae, Takahiro Arima, Gerald G. Schumann, Kathleen H. Burns and Michael J. Soares
- Organizer
  KEYSTONE SYMPOSIUM 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] ARTによるエピジェネティクスの変調2018
- Author(s)
  小林記緒、樋浦仁、岡江寛明、有馬隆博
- Organizer
  第63回日本生殖医学会学術講演会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] ARTによるエピジェネティクスの変調2018
- Author(s)
  小林記緒、樋浦仁、岡江寛明、有馬隆博
- Organizer
  第63回日本生殖医学会学術講演会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09216
[Presentation] ヒト胎盤のトロフォブラスト幹細胞の樹立と臨床への応用2018
- Author(s)
  小林記緒、樋浦仁、岡江寛明、有馬隆博
- Organizer
  第70回日本産科婦人科学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] Derivation of Human Trophoblast Stem Cells from Blastocysts and Villous Cytotrophoblast Cells2017
- Author(s)
  Arima T, Okae H
- Organizer
  IHEC Science Days & Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] ヒト胎盤栄養膜幹細胞の樹立とエピゲノム特性2017
- Author(s)
  岡江寛明、有馬隆博
- Organizer
  第25回日本胎盤学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04335
[Presentation] Derivation of Human Trophoblast Stem Cells from Blastocysts and Villous Cytotrophoblast Cells2017
- Author(s)
  Arima T, Okae H
- Organizer
  IHEC Science Days & Annual Meeting 2017
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] ヒト胎盤栄養膜幹細胞の樹立とエピゲノム特性2017
- Author(s)
  岡江寛明、有馬隆博
- Organizer
  第25回日本胎盤学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] Establishment of human trophoblast stem cells2017
- Author(s)
  岡江寛明
- Organizer
  京大医学部セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] 分化多能性を持つヒト胎盤栄養膜幹細胞の樹立2016
- Author(s)
  岡江寛明、有馬隆博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] 繁殖期におけるマウス精子DNAメチル化様式の加齢性変化2016
- Author(s)
  小林記緒、岡江寛明、樋浦仁、千葉初音、白形芳樹、原健士郎、種村健太郎、有馬隆博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] ウシ卵胞内卵子の発生能を制御する卵丘細胞シグナルネットワーク2016
- Author(s)
  杉村智史、岡江寛明、有馬隆博
- Organizer
  第109回日本繁殖生物学会大会
- Place of Presentation
  麻布大学（神奈川県相模原市）
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] Incomplete erasure of germline DNA methylation in the human placenta2016
- Author(s)
  岡江寛明
- Organizer
  1.新学術領域研究「生殖細胞のエピゲノムダイナミクスとその制御」International Symposium
- Place of Presentation
  京都大学百周年時計台記念館（京都府宇治市）
- Year and Date
  2016-02-17
- Data Source
  KAKENHI-PUBLICLY-26112502
[Presentation] ヒト凍結融解胚移植胎盤におけるmicroRNAの網羅的解析2016
- Author(s)
  樋浦仁、服部裕充、岡江寛明、千葉初音、宮内尚子、北村茜、菊地裕幸、吉田秋仁、有馬隆博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] Transcriptome profiling of purified human trophoblast cells2016
- Author(s)
  Hamada H, Sato T, Okae H, Yaegashi N, and Arima T.
- Organizer
  63th Annual Scientific Meeting
- Place of Presentation
  Montreal, QC, Canada
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112502
[Presentation] ヒト凍結融解胚移植胎盤におけるmicroRNAの網羅的解析2016
- Author(s)
  樋浦仁、服部裕充、岡江寛明、千葉初音、宮内尚子、北村茜、菊地裕幸、吉田秋仁、有馬隆博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] ウシ卵胞内卵子の発生能を制御する卵丘細胞シグナルネットワーク2016
- Author(s)
  杉村智史、岡江寛明、有馬隆博
- Organizer
  第109回日本繁殖生物学会大会
- Place of Presentation
  麻布大学（神奈川県相模原市）
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] Incomplete reprogramming of germline DNA methylation in the human placenta2016
- Author(s)
  Arima T, Okae H
- Organizer
  IHEC Science Days & Annual Meeting 2016
- Place of Presentation
  Crowne Plaza Brussels-LePalace（Belgium、Brussels）
- Year and Date
  2016-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] 分化多能性を持つヒト胎盤栄養膜幹細胞の樹立2016
- Author(s)
  岡江寛明、有馬隆博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] Incomplete reprogramming of germline DNA methylation in the human placenta2016
- Author(s)
  Arima T, Okae H
- Organizer
  IHEC Science Days & Annual Meeting 2016
- Place of Presentation
  Crowne Plaza Brussels-LePalace(Belgian, Brussels)
- Year and Date
  2016-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] Transcriptome profiling of purified human trophoblast cells2016
- Author(s)
  Hamada H, Sato T, Okae H, Yaegashi N, and Arima T.
- Organizer
  63th Annual Scientific Meeting
- Place of Presentation
  Montreal, QC, Canada
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] Transcriptome profiling of purified human trophoblast cells2016
- Author(s)
  Hamada H, Sato T, Okae H, Yaegashi N, and Arima T.
- Organizer
  63th Annual Scientific Meeting
- Place of Presentation
  Montreal, QC, Canada
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] 繁殖期におけるマウス精子DNAメチル化様式の加齢性変化2016
- Author(s)
  小林記緒、岡江寛明、樋浦仁、千葉初音、白形芳樹、原健士郎、種村健太郎、有馬隆博
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] ヒト胎盤におけるインプリント型X染色体不活性化2015
- Author(s)
  濱田裕貴、岡江寛明、八重樫伸生、有馬隆博
- Organizer
  第23回日本胎盤学会学術集会
- Place of Presentation
  JA共済ビル（東京都千代田区）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] ヒト胚発生におけるエピジェネティクスの変調2015
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、千葉初音、宮内尚子
- Organizer
  第33回受精着床学会
- Place of Presentation
  TFTホール（東京都江東区）
- Year and Date
  2015-11-26
- Invited
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] DNA methylation dynamics and regulation of genomic imprinting during human development2015
- Author(s)
  Okae H, Arima T.
- Organizer
  EMBO Workshop
- Place of Presentation
  Gottingen, Germany
- Year and Date
  2015-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10657
[Presentation] ヒト胎盤におけるインプリント型X染色体不活性化2015
- Author(s)
  濱田裕貴、岡江寛明、八重樫伸生、有馬隆博
- Organizer
  第23回日本胎盤学会学術集会
- Place of Presentation
  JA共済ホール（東京千代田区）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PUBLICLY-26112502
[Presentation] ヒト初期発生過程におけるインプリンティング制御2015
- Author(s)
  岡江寛明
- Organizer
  2.新学術領域研究「生殖細胞のエピゲノムダイナミクスとその制御」若手勉強会
- Place of Presentation
  ラフォーレ修繕寺（静岡県伊豆市）
- Year and Date
  2015-07-22
- Data Source
  KAKENHI-PUBLICLY-26112502
[Presentation] DNA methylation dynamics and regulation of genomic imprinting during human development2015
- Author(s)
  Okae H, Arima T
- Organizer
  EMBO Workshop
- Place of Presentation
  Montreal, QC, Canada
- Year and Date
  2015-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] DNA methylation dynamics and regulation of genomic imprinting during human development2015
- Author(s)
  Okae H, Arima T
- Organizer
  EMBO Workshop
- Place of Presentation
  Gottingen, Germany
- Year and Date
  2015-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112502
[Presentation] ヒト胎盤におけるインプリント型X染色体不活性化2015
- Author(s)
  濱田裕貴、岡江寛明、八重樫伸生、有馬隆博
- Organizer
  第23回日本胎盤学会学術集会
- Place of Presentation
  JA共済ビル（東京都千代田区）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-15K15592
[Presentation] ヒト胚発生におけるエピジェネティクスの変調2015
- Author(s)
  有馬隆博、樋浦仁、岡江寛明、千葉初音、宮内尚子
- Organizer
  第33回受精着床学会
- Place of Presentation
  TFTホール（東京都江東区）
- Year and Date
  2015-11-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112502
[Presentation] Non-random loss of imprinting in cloned mice2012
- Author(s)
  岡江寛明、有馬隆博
- Organizer
  第5回生殖系列の世代サイクルとエピゲノムネットワーク
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24613001
[Presentation] Genome-wide analysis of DNA methylation dynamics during early human development
- Author(s)
  Arima T. Okae H.
- Organizer
  12.International Human Epigenome Consortium (IHEC) Annual Meeting
- Place of Presentation
  Vancouver, Canada.
- Year and Date
  2014-10-06 – 2014-10-08
- Data Source
  KAKENHI-PUBLICLY-26112502
[Presentation] Genome-wide analysis of DNA methylation dynamics during early human development
- Author(s)
  Arima T. Okae H.
- Organizer
  International Human Epigenome Consortium (IHEC) Annual Meeting
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-10-06 – 2014-10-08
- Data Source
  KAKENHI-PROJECT-24613001
[]

1. ARIMA Takahiro (80253532)

# of Collaborated Projects: 11 results

# of Collaborated Products: 137 results
2. HIURA Hitoshi (70451523)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
3. 柴田峻 (40885670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. MIYAUCHI Naoko (60596162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. YAEGASHI Nobuo (00241597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. NAKAI Kunihiko (00291336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SUGAWARA Junichi (60280880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 大日向康秀 (70415107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HARA Kenshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 小林記緒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 堀武志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 梶弘和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 小林枝里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okae Hiroaki 岡江 寛明

OKAE Hiroaki 岡江 寛明

Research Projects

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ヒト幹細胞を用いた器官形成原理の構成的理解Principal Investigator

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ヒト胎盤の発生を支える分子基盤の包括的な理解Principal Investigator

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Investigation of a novel genomic imprinting mechanism in the human placentaPrincipal Investigator

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Innovative disease modeling of pregnancy complications using human trophoblast stem cellsPrincipal Investigator

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Reconstruction of totipotency using stem cells derived from preimplantation embryosPrincipal Investigator

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Investigation of the molecular basis of extraembryonic lineage specification in humansPrincipal Investigator

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Genomic imprinting in the human placentaPrincipal Investigator

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ヒト生殖細胞のエピゲノムダイナミクスとその制御機構Principal Investigator

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Functional analysis of a placenta-specific imprinted gene Gab1 in the placentaPrincipal Investigator

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Okae Hiroaki 岡江寛明

OKAE Hiroaki 岡江寛明