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Nakamura Akiyoshi  中村 彰良

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NAKAMURA Akiyoshi  中村 彰良

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Researcher Number 10583891
Other IDs
Affiliation (Current) 2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help 2022 – 2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
2017 – 2022: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員
2016: 国立研究開発法人産業技術総合研究所, 生物プロセス研究部門, 研究員
2011: 北海道大学, 大学院・先端生命科学研究院, 博士研究員
2010: 北海道大学, 先端生命科学研究院, 博士研究員
Review Section/Research Field
Principal Investigator
Structural biochemistry / Basic Section 43010:Molecular biology-related / Basic Section 43020:Structural biochemistry-related
Keywords
Principal Investigator
アミノアシルtRNA合成酵素 / 鋳型依存伸長反応 / タンパク質 / 核酸 / DNA/RNAポリメラーゼ / tRNA / 逆向き重合 / タンパク質-核酸相互作用 / 酵素 / tRNA修飾 … More / X線結晶構造解析 / tRNA断片 / 立体構造解析 / 3'-5'方向塩基伸長 / 鋳型依存塩基伸長 / X線結晶構造 Less
  • Research Projects

    (4 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (1 People)
  •  The regulatory mechanism of gene expression via tRNA fragments generated by 3'-5' polymerasePrincipal Investigator

    • Principal Investigator
      中村 彰良
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Molecular basis of 3'-5' polymerase in a diverse RNA recognitionPrincipal Investigator

    • Principal Investigator
      NAKAMURA Akiyoshi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Study on a switching mechanism in RNA recognition by 3'-5' RNA polymerasePrincipal Investigator

    • Principal Investigator
      NAKAMURA Akiyoshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Structural basis for the indirect aminoacyl-tRNA synthesis pathway from H. pyroliPrincipal Investigator

    • Principal Investigator
      NAKAMURA Akiyoshi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Structural biochemistry
    • Research Institution
      Hokkaido University

All 2021 2020 2019 2018 2017 2012 2010

All Journal Article Presentation

  • [Journal Article] Analysis of GTP addition in the reverse (3′-5′) direction by human tRNA(His) guanylyltransferase2021

    • Author(s)
      Nakamura Akiyoshi、Wang Daole、Komatsu Yasuo
    • Journal Title

      RNA

      Volume: 27 Issue: 6 Pages: 665-675

    • DOI

      10.1261/rna.078287.120

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03372, KAKENHI-PROJECT-19K06519
  • [Journal Article] Biochemical analysis of human tRNAHis guanylyltransferase in mitochondrial tRNAHis maturation2018

    • Author(s)
      Nakamura Akiyoshi、Wang Daole、Komatsu Yasuo
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 503 Issue: 3 Pages: 2015-2021

    • DOI

      10.1016/j.bbrc.2018.07.150

    • NAID

      120006718707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K18511, KAKENHI-PROJECT-16H05106
  • [Journal Article] Molecular mechanism of substrate recognition and specificity of tRNAHis guanylyltransferase during nucleotide addition in the 3′-5′ direction2018

    • Author(s)
      Nakamura Akiyoshi、Wang Daole、Komatsu Yasuo
    • Journal Title

      RNA

      Volume: 24 Issue: 11 Pages: 1583-1593

    • DOI

      10.1261/rna.067330.118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K18511, KAKENHI-PROJECT-16H05106
  • [Presentation] Human tRNAHis guanylyltransferaseのヌクレオチド認識機構の解明2021

    • Author(s)
      中村 彰良、汪 道楽、小松 康雄
    • Organizer
      令和3年(2021年)度日本結晶学会年会
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] ヒト由来tRNAHisグアニルトランスフェラーゼによる逆方向(3′-5′)の塩基付加反応の解析とRNA5’末端修飾への応用2021

    • Author(s)
      中村 彰良、汪 道楽、小松 康雄
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] ヒト由来tRNAHis guanylyltransferaseのヌクレオチド認識機構2021

    • Author(s)
      中村 彰良
    • Organizer
      2020年度量子ビームサイエンスフェスタ
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] Human tRNAHis guanylyltransferaseのRNA複合体構造解析2020

    • Author(s)
      中村彰良、汪道楽、小松 康雄
    • Organizer
      2019年度量子ビームサイエンスフェスタ
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] Nucleotide recognition mechanism of human tRNAHis guanylyltransferase and its application to RNA 5′-modification2020

    • Author(s)
      中村 彰良、汪 道楽、小松 康雄
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] 2-セレノウリジン合成酵素SelUのtRNA選択性2020

    • Author(s)
      碓井 拓哉, 大江 花, 中村 彰良, 尾瀬 農之, 姚 閔
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] The nucleotide recognition mechanism of human tRNAHis guanylyltransferase in 3′-5′ nucleotide addition reaction2019

    • Author(s)
      Akiyoshi Nakamura, Daole Wang, Yasuo Komatsu
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] ヒト由来tRNAHis guanylyltransferaseの立体構造解析2019

    • Author(s)
      中村彰良
    • Organizer
      2018年度量子ビームサイエンスフェスタ
    • Data Source
      KAKENHI-PROJECT-16K18511
  • [Presentation] ヒト由来tRNAHis guanylyltransferaseによるミトコンドリアtRNAHisの5′末端修飾反応の解析2019

    • Author(s)
      中村彰良、汪道楽、小松 康雄
    • Organizer
      第21回日本RNA学会
    • Data Source
      KAKENHI-PROJECT-19K06519
  • [Presentation] Human tRNAHis guanylyltransferase の機能解析2018

    • Author(s)
      中村彰良, 汪道楽, 小松康雄
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K18511
  • [Presentation] 3′-5′方向塩基伸長を触媒するtRNA修飾酵素の基質特異性解析2017

    • Author(s)
      中村彰良、汪道楽、小松康雄
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      東北大学川内キャンパス (仙台市)
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K18511
  • [Presentation] Asn-tRNA(Asn) synthesis in a Bacterial Transamidosome2012

    • Author(s)
      Tateki Suzuki, Akiyoshi Nakamura, Min Yao, and Isao Tanaka
    • Organizer
      Sapporo Symposium on Advanced Protein Crystallography
    • Place of Presentation
      北海道大学(札幌市)
    • Data Source
      KAKENHI-PROJECT-22870001
  • [Presentation] Structural and Functional analysis of GatCAB Sapporo2012

    • Author(s)
      Akiyoshi Nakamura
    • Place of Presentation
      北海道大学(札幌市)
    • Data Source
      KAKENHI-PROJECT-22870001
  • [Presentation] Asn-tRNA (Asn) synthesis in a Bacterial Transamidosome2012

    • Author(s)
      Tateki Suzuki, Akiyoshi Nakamura, Min Yao, Isao Tanaka
    • Organizer
      Sapporo Symposium on Advanced Protein Crystallography
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-22870001
  • [Presentation] Structural and Functional analysis of GatCAB2012

    • Author(s)
      Akiyoshi Nakamura
    • Organizer
      Sapporo Symposium on Advanced Protein Crystallography
    • Place of Presentation
      北海道大学(札幌市)(招待講演)
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-22870001
  • [Presentation] 真正細菌型GatCABと古細菌型GatCABの構造比較2010

    • Author(s)
      中村彰良・周倩・朝野希美・姚閔・田中勲
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Data Source
      KAKENHI-PROJECT-22870001
  • [Presentation] 古細菌型GatCABと真正細菌型GatCABの比較2010

    • Author(s)
      周倩・中村彰良・朝野希美・姚閔・田中勲
    • Organizer
      第60回日本結晶学会年会
    • Place of Presentation
      大阪大学コンベンションセンター(大阪府)
    • Data Source
      KAKENHI-PROJECT-22870001
  • 1.  小松 康雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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