Ohtsu Naoki 大津直樹

Researcher Number	10588403
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2020: 北海道大学, 遺伝子病制御研究所, 助教
Review Section/Research Field	Principal Investigator Tumor therapeutics / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator Eva1 / グリオブラストーマ / グリオーマ幹細胞 / Glioblastoma: multiform / Glioma-initiating cell / NF-kB pathway / Genome editing / RelA / RelB / NFｋB2 … More / Glioblastoma / NF-kB2 / Chemical Screening / NF-kB / 分子標的薬 / Chemical screening / NF-kN / 人工グリオーマ幹細胞 / ゲノム編集 / 遺伝子治療 / p53 / 人工グリオブラストーマ幹細胞 / 増殖抑制 Less

Development of growth inhibitory vectors for Eva1-positive glioma stem cells using genome editingPrincipal Investigator
- Principal Investigator
  
  Ohtsu Naoki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hokkaido University
Search of RelB-NFkB2 signal inhibitor using Glioma-initiating cellsPrincipal Investigator
- Principal Investigator
  
  Ohtsu Naoki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Hokkaido University

All 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Chemical screening identifies EUrd as a novel inhibitor against Temozolomide-resistant glioblastoma-initiating cells.2016
- Author(s)
  Tsukamoto Y, Ohtsu N, Echizenya S, Otsuguro S, Ogura R, Natsumeda M, Isogawa M, Aoki H, Ichikawa S, Sakaitani M, Matsuda A, Maenaka K, Fujii Y, Kondo T.
- Journal Title
  
  Stem Cells
  
  Volume: - Pages: 2016-2025
- DOI
  10.1002/stem.2380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861141, KAKENHI-PROJECT-25462247, KAKENHI-PROJECT-16K18447
[Presentation] Visualization of Eva1-positive glioma stem cell interactions with blood vessels2020
- Author(s)
  大津直樹
- Organizer
  第43回分子生物学会
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] 透明化脳を用いたグリオーマ浸潤の観察と分子メカニズムの解析2020
- Author(s)
  大津直樹
- Organizer
  第6回部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] ゲノム編集を介したグリオーマ幹細胞の誘導2019
- Author(s)
  大津直樹
- Organizer
  細胞を作る会
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] ゲノム編集を用いたEva1陽性細胞の検出と抑制2019
- Author(s)
  大津直樹
- Organizer
  北海道大学IGM交流会
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] ゲノム編集を用いたグリオーマ幹細胞の樹立と浸潤能について2019
- Author(s)
  大津直樹
- Organizer
  北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] ゲノム編集を用いたEva1+細胞の増殖抑制方法の開発2019
- Author(s)
  大津直樹
- Organizer
  北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-16K18447
[Presentation] ゲノム編集を用いたグリオーマ幹細胞の樹立及びEva1陽性細胞の検出と増殖抑制2019
- Author(s)
  大津直樹
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] ゲノム編集を用いたEva1+細胞の増殖抑制方法の開発2019
- Author(s)
  大津直樹
- Organizer
  北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] ゲノム編集を用いたグリオーマ幹細胞の樹立と浸潤について2019
- Author(s)
  大津直樹
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] ゲノム編集を用いたEva1陽性細胞の検出と抑制2019
- Author(s)
  大津直樹
- Organizer
  北海道大学IGM交流会
- Data Source
  KAKENHI-PROJECT-16K18447
[Presentation] 神経幹細胞がグリオーマ幹細胞に変化するプロセスにおけるEva1遺伝子の発現モニタリング2018
- Author(s)
  大津直樹、近藤亨
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K18447
[Presentation] 神経幹細胞がグリオーマ幹細胞に変化するプロセスにおけるEva1遺伝子の発現モニタリング2018
- Author(s)
  大津直樹、近藤亨
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K07317
[Presentation] Eva1はNF-kBシグナルを介してグリオーマを悪性化する2017
- Author(s)
  大津直樹
- Organizer
  第二回北大・部局横断シンポジウム「免疫・癌・感染」
- Place of Presentation
  北海道大学 (北海道札幌市)
- Data Source
  KAKENHI-PROJECT-16K18447
[Presentation] Inhibition of Eva1 degrade the formation and development of glioblastomas2017
- Author(s)
  Naoki Ohtsu
- Organizer
  2nd International conference on Tumor & Cancer Immunology and Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18447
[Presentation] Eva1 maintains the characteristics of GBM through the activation of non-canonical NF-kB signaling pathway2016
- Author(s)
  Ohtsu N.
- Organizer
  Kanazawa Univ-Hokkaido Univ International Cancer Forum for Young Scientists
- Place of Presentation
  Hokkaido University (Sapporo, Hokkaido, Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18447
[Presentation] グリオブラストーマ幹細胞に高発現している膜タンパク質Eva1の機能解析2016
- Author(s)
  大津直樹
- Organizer
  第112 回北海道癌談話会春期シンポジウム
- Place of Presentation
  TKP ガーデンシティ (北海道札幌市)
- Data Source
  KAKENHI-PROJECT-16K18447

1. FUJII Yukihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. AOKI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. TSUKAMOTO Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小倉良介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohtsu Naoki 大津 直樹

Research Projects

Research Products

Co-Researchers

Development of growth inhibitory vectors for Eva1-positive glioma stem cells using genome editingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search of RelB-NFkB2 signal inhibitor using Glioma-initiating cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Chemical screening identifies EUrd as a novel inhibitor against Temozolomide-resistant glioblastoma-initiating cells.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Visualization of Eva1-positive glioma stem cell interactions with blood vessels2020

Author(s)

Organizer

Data Source

[Presentation] 透明化脳を用いたグリオーマ浸潤の観察と分子メカニズムの解析2020

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を介したグリオーマ幹細胞の誘導2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を用いたEva1陽性細胞の検出と抑制2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を用いたグリオーマ幹細胞の樹立と浸潤能について2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を用いたEva1+細胞の増殖抑制方法の開発2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を用いたグリオーマ幹細胞の樹立及びEva1陽性細胞の検出と増殖抑制2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を用いたEva1+細胞の増殖抑制方法の開発2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を用いたグリオーマ幹細胞の樹立と浸潤について2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集を用いたEva1陽性細胞の検出と抑制2019

Author(s)

Organizer

Data Source

[Presentation] 神経幹細胞がグリオーマ幹細胞に変化するプロセスにおけるEva1遺伝子の発現モニタリング2018

Author(s)

Organizer

Data Source

[Presentation] 神経幹細胞がグリオーマ幹細胞に変化するプロセスにおけるEva1遺伝子の発現モニタリング2018

Author(s)

Organizer

Data Source

[Presentation] Eva1はNF-kBシグナルを介してグリオーマを悪性化する2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Inhibition of Eva1 degrade the formation and development of glioblastomas2017

Author(s)

Organizer

Data Source

[Presentation] Eva1 maintains the characteristics of GBM through the activation of non-canonical NF-kB signaling pathway2016

Author(s)

Ohtsu Naoki 大津直樹