SAKURAI Chiye 櫻井千恵

… Alternative Names

櫻井千恵サクライチエ

Sakurai Chiye 櫻井千恵

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Researcher Number	10589724
Other IDs
Affiliation (Current)	2025: 鳥取大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 鳥取大学, 医学部, 助教 2014 – 2016: 鳥取大学, 医学部, 助教 2013: 福島県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / General medical chemistry
Keywords	Principal Investigator ファゴソーム / ファゴサイトーシス / SNAREタンパク / メンブレントラフィック / リン酸化 / クラスリン / 受容体 / SNAREタンパク質 / FRET解析 / 膜輸送 / マクロファージ / 膜融合

自然免疫を制御する膜融合タンパクの協働性：新たな膜融合経路による制御機構Principal Investigator
- Principal Investigator
  
  櫻井千恵
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tottori University
Molecular mechanisms of biological defense in macrophages: Membrane transport control mechanisms dependent on foreign particlesPrincipal Investigator
- Principal Investigator
  
  SAKURAI Chiye
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tottori University
Analyses of the regulatory mechanism in phagosome maturation by phosphorylation of SNAP-23Principal Investigator
- Principal Investigator
  
  Sakurai Chiye
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tottori University
  Fukushima Medical University

All 2024 2023 2020 2019 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in macrophages2024
- Author(s)
  Sakurai Chiye、Yamashita Natsumi、Azuma Kento、Hatsuzawa Kiyotaka
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 35 Issue: 3
- DOI
  10.1091/mbc.e23-04-0149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06389
[Journal Article] Characterization of MORN2 stability and regulatory function in LC3-associated phagocytosis in macrophages2020
- Author(s)
  Maya Morita, Mayu Kajiye, Chiye Sakurai, Shuichi Kubo, Miki Takahashi, Daiki Kinoshita, Naohiro Hori, Kiyotaka Hatsuzawa
- Journal Title
  
  Biol Open.
  
  Volume: 9
- DOI
  10.1242/bio.051029
- NAID
  120007170660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06641, KAKENHI-PROJECT-19K16519
[Journal Article] Regulatory Mechanism of SNAP23 in Phagosome Formation and Maturation2020
- Author(s)
  Kiyotaka Hatsuzawa, Chiye Sakurai
- Journal Title
  
  Yonago Acta Med.
  
  Volume: 63 Issue: 3 Pages: 135-145
- DOI
  10.33160/yam.2020.08.001
- NAID
  130007888758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06641, KAKENHI-PROJECT-19K16519
[Journal Article] Increased PD-1-positive macrophages in the tissue of gastric cancer are closely associated with poor prognosis in gastric cancer patients2020
- Author(s)
  Kono, Y. Saito, H. Miyauchi, W. Shimizu, S. Murakami, Y. Shishido, Y. Miyatani, K. Matsunaga, T. Fukumoto, Y. Nakayama, Y. Sakurai, C. Hatsuzawa, K. Fujiwara, Y.
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 175-183
- DOI
  10.1186/s12885-020-6629-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06183, KAKENHI-PROJECT-19K16519
[Journal Article] Syntaxin 11 regulates the stimulus-dependent transport of Toll-like receptor 4 to the plasma membrane by cooperating with SNAP-23 in macrophages2019
- Author(s)
  Kinoshita Daiki、Sakurai Chiye、Morita Maya、Tsunematsu Masashi、Hori Naohiro、Hatsuzawa Kiyotaka
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 30 Issue: 9 Pages: 1085-1097
- DOI
  10.1091/mbc.e18-10-0653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16519
[Journal Article] ファゴソームの形成と成熟の分子機構2015
- Author(s)
  初沢清隆、櫻井千恵
- Journal Title
  
  細胞工学
  
  Volume: 34（2） Pages: 155-160
- Data Source
  KAKENHI-PROJECT-25860218
[Presentation] VAMP5はSNAP23の構造を変化させることでファゴソーム成熟に間接的に機能する2023
- Author(s)
  櫻井千恵、河野信、初沢清隆
- Organizer
  第75回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-23K06389
[Presentation] MORN2はSNAP-23のファゴソーム膜局在量を増加させ、非標準的オートファジーを亢進する2020
- Author(s)
  森田真矢、梶江真由、櫻井千恵、初沢清隆
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-19K16519
[Presentation] Partial cleavage of MORN2, a LAP(LC3-associated phagocytosis)-related factor, is regulated by the ubiquitinproteasome system in macrophages2020
- Author(s)
  初沢清隆、梶江真由、髙橋美紀、森田真矢、櫻井千恵
- Organizer
  日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-19K16519
[Presentation] The role of phosphorylation of SNAP-23 at Ser95 in an immunoreceptor-dependent manner during phagocytosis2020
- Author(s)
  櫻井千恵、初沢清隆
- Organizer
  日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-19K16519
[Presentation] SNAP-23 is involved in MORN2-dependent LC3-associated phagocytosis2019
- Author(s)
  森田真矢，櫻井千恵，初沢清隆
- Organizer
  日本蛋白質科学会/日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-19K16519
[Presentation] Syntaxin11 regulates the toll-like receptor 4 trafficking from recycling endosomes to the plasma membrane in LPS-stimulated macrophages2019
- Author(s)
  木下大生，森田真矢，常松眞史，櫻井千恵，初沢清隆
- Organizer
  日本蛋白質科学会/日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-19K16519
[Presentation] VAMP5 regulates phagosome formation in an immunoreceptor-dependent manner2019
- Author(s)
  櫻井千恵，東健人，山下菜摘，初沢清隆
- Organizer
  日本蛋白質科学会/日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-19K16519
[Presentation] IKK2依存的なSNAP-23のリン酸化はファゴソームの成熟化を負に制御する2016
- Author(s)
  櫻井千恵、和田郁夫、初沢清隆
- Organizer
  日本生化学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-25860218
[Presentation] Ser95 phosphorylation of SNAP-23 by IKK2 regulates the process of phagocytosis in macrophages2015
- Author(s)
  櫻井千恵、和田郁夫、初沢清隆
- Organizer
  日本分子生物学会／日本生化学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25860218
[Presentation] Syntaxin11はtoll様受容体4の細胞膜局在化に関与する2015
- Author(s)
  木下大生、森田真矢、櫻井千恵、初沢清隆
- Organizer
  日本分子生物学会／日本生化学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25860218
[Presentation] Ser95 phosphorylation of SNAP-23 causes a decrease in phagocytosis2013
- Author(s)
  櫻井千恵、初沢清隆、和田郁夫
- Organizer
  日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-25860218
[Presentation] SNAP-23のSer95リン酸化はファゴサイトーシスを抑制する
- Author(s)
  櫻井千恵、和田郁夫、初沢清隆
- Organizer
  日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂、東大寺総合文化センター（奈良県奈良市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-25860218

1. 初沢清隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 中山祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKURAI Chiye 櫻井 千恵

櫻井 千恵 サクライ チエ

Sakurai Chiye 櫻井 千恵

Research Projects

Research Products

Co-Researchers

自然免疫を制御する膜融合タンパクの協働性：新たな膜融合経路による制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of biological defense in macrophages: Membrane transport control mechanisms dependent on foreign particlesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of the regulatory mechanism in phagosome maturation by phosphorylation of SNAP-23Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in macrophages2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of MORN2 stability and regulatory function in LC3-associated phagocytosis in macrophages2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Regulatory Mechanism of SNAP23 in Phagosome Formation and Maturation2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Increased PD-1-positive macrophages in the tissue of gastric cancer are closely associated with poor prognosis in gastric cancer patients2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Syntaxin 11 regulates the stimulus-dependent transport of Toll-like receptor 4 to the plasma membrane by cooperating with SNAP-23 in macrophages2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ファゴソームの形成と成熟の分子機構2015

Author(s)

Journal Title

Data Source

[Presentation] VAMP5はSNAP23の構造を変化させることでファゴソーム成熟に間接的に機能する2023

Author(s)

Organizer

Data Source

[Presentation] MORN2はSNAP-23のファゴソーム膜局在量を増加させ、非標準的オートファジーを亢進する2020

Author(s)

Organizer

Data Source

[Presentation] Partial cleavage of MORN2, a LAP(LC3-associated phagocytosis)-related factor, is regulated by the ubiquitinproteasome system in macrophages2020

Author(s)

Organizer

Data Source

[Presentation] The role of phosphorylation of SNAP-23 at Ser95 in an immunoreceptor-dependent manner during phagocytosis2020

Author(s)

Organizer

Data Source

[Presentation] SNAP-23 is involved in MORN2-dependent LC3-associated phagocytosis2019

Author(s)

Organizer

Data Source

[Presentation] Syntaxin11 regulates the toll-like receptor 4 trafficking from recycling endosomes to the plasma membrane in LPS-stimulated macrophages2019

Author(s)

Organizer

Data Source

[Presentation] VAMP5 regulates phagosome formation in an immunoreceptor-dependent manner2019

SAKURAI Chiye 櫻井千恵

櫻井千恵サクライチエ

Sakurai Chiye 櫻井千恵