HOZUMI Shunya 穂積俊矢

Researcher Number	10597222
Other IDs
Affiliation (based on the past Project Information) *help	2019: 広島大学, 統合生命科学研究科(理), 助教 2016: 広島大学, 理学研究科, 助教 2012 – 2015: 広島大学, 理学(系)研究科(研究院), 助教 2013: 広島大学, 大学院理学研究科, 助教 2011: 広島大学, 理学(系)研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Medical genome science / Basic Section 50010:Tumor biology-related Except Principal Investigator epigenetics / Genome biology
Keywords	Principal Investigator 分化転換 / 神経細胞 / 内胚葉 / 中胚葉 / 遺伝子発現 / Notch / エピジェネティクス / 細胞運命 / 中枢神経系 / Notch情報伝達系 … More / ゼブラフィッシュ / 網膜 / 脊椎 / 中内胚葉 / 遺伝子発現制御 / がん微小環境 / 神経 / ライブイメージング … More Except Principal Investigator ゼブラフィッシュ / 再生 / 変異体 / スクリーニング / 脱メチル化 / 発生 / 脱メチル化因子 / トランスクリプトーム解析 / トランスクリプトーム Less

神経軸索のシナプスを介したメラノーマ細胞とがん微小環境の相互作用メカニズムの解明Principal Investigator
- Principal Investigator
  
  穂積俊矢
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hiroshima University
Elucidation of dedifferentiation mechanism by transcriptome analysis
- Principal Investigator
  
  Kikuchi Yutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Hiroshima University
Genome-wide analysis of novel molecular mechanism of direct reprogramming from retinal stem cell to pancreatic cellPrincipal Investigator
- Principal Investigator
  
  HOZUMI Shunya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical genome science
- Research Institution
  Hiroshima University
Genome wide screening of genomic DNA demethylation factors by genetic method.
- Principal Investigator
  
  KIKUCHI Yutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  epigenetics
- Research Institution
  Hiroshima University

All 2019 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Histone H3 Lysine 27 Trimethylation Leads to Loss of Mesendodermal Competence During Gastrulation in Zebrafish Ectodermal Cells2017
- Author(s)
  Shiomi T., Muto A., Hozumi S., Kimura H., and Kikuchi, Y.
- Journal Title
  
  Zoological Science
  
  Volume: 34 Issue: 1 Pages: 64-64
- DOI
  10.2108/zs160032
- NAID
  210000176852
- ISSN
  0289-0003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430185
[Journal Article] Expression patterns of dnmt3aa, dnmt3ab, and dnmt4 during development and fin regeneration in zebrafish.2014
- Author(s)
  Takayama, K., Shimoda, N., Takanaga, S., Hozumi, S. and Kikuchi, Y.
- Journal Title
  
  Gene Expression Patterns
  
  Volume: 14 Pages: 105-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23616002
[Journal Article] Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins.2014
- Author(s)
  Hirose K, Shiomi T, Hozumi S, Kikuchi Y.
- Journal Title
  
  BMC Developmental Biology
  
  Volume: 14 Pages: 42-42
- DOI
  10.1186/s12861-014-0042-9
- NAID
  120006579521
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J06771, KAKENHI-PROJECT-26430185
[Journal Article] Expression patterns of dnmt3aa, dnmt3ab, and dnmt4 during development and fin regeneration in zebrafish.2014
- Author(s)
  K Takayama, N Shimoda, S Takanaga, S Hozumi, Y Kikuchi.
- Journal Title
  
  Gene Expression Patterns
  
  Volume: 14(2) Pages: 105-110
- DOI
  10.1016/j.gep.2014.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710221, KAKENHI-PROJECT-26430185
[Journal Article] Ddx46 Is Required for Multi-Lineage Differentiation of Hematopoietic Stem Cells in Zebrafish2013
- Author(s)
  R Hirabayashi*, S Hozumi*, S Higashijima, Y Kikuchi. (*These two authors contributed equally to this work)
- Journal Title
  
  Stem Cells and Development
  
  Volume: 22(18) Pages: 2532-2542
- DOI
  10.1089/scd.2012.0623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710221
[Journal Article] Ddx46 Is Required for Multi-Lineage Differentiation of Hematopoietic Stem Cells in Zebrafish.2013
- Author(s)
  Hirabayashi, R., Hozumi, S., Higashijima, S. and Kikuchi, Y.
- Journal Title
  
  Stem Cells and Development
  
  Volume: 22 Pages: 2532-2542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23616002
[Journal Article] DEAD-Box Protein Ddx46 Is Required for the Development of the Digestive Organs and Brain in Zebrafish.2012
- Author(s)
  Hozumi, S., Hirabayashi, R., Yoshizawa, A., Ogata, M., Ishitani, T., Tsutsumi, M., Kuroiwa, A., Itoh, M. and Kikuchi, Y.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23616002
[Journal Article] DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish.2012
- Author(s)
  Hozumi S.
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- DOI
  10.1371/journal.pone.0033675
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23128506, KAKENHI-PROJECT-24370080, KAKENHI-PROJECT-24710221
[Presentation] Tumor invasion and progression are associated with cholinergic-nerves via nicotinic acetylcholine receptors2019
- Author(s)
  Mohamed N. Bakr, Shunya Hozumi, Hiroya Katayama, Haruko Takahashi, Yukinari Haraoka, Tohru Ishitani, Yutaka Kikuchi
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07689
[Presentation] 核の移動制御を介したNodalシグナルによる内胚葉分化機構の解明2016
- Author(s)
  穂積俊矢，青木駿，菊池　裕
- Organizer
  日本遺伝学会
- Place of Presentation
  三島市
- Year and Date
  2016-09-07
- Invited
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] ゼブラフィッシュ初期発生における核内F-アクチンの機能解析2016
- Author(s)
  青木駿, 穂積俊矢, 菊池裕
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] 脊椎動物の中内胚葉分離における時空間的制御機構の解析2015
- Author(s)
  穂積俊矢，青木　駿，菊池　裕
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  東北大学川内北キャンパス
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] ゼブラフィッシュ尾ビレ再生におけるmTORC1の機能解析2015
- Author(s)
  廣瀬健太郎，高山和也，塩見太志，穂積俊矢，菊池　裕
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] 脊椎動物の中内胚葉分離における時空間的制御機構の解析2015
- Author(s)
  穂積俊矢，青木　駿，菊池　裕
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] The DEAD-box protein Ddx46 is involved in pre-mRNA splicing for development of digestive organs and brain in zebrafish.2011
- Author(s)
  Shunya Hozumi, Ryo Hirabayashi, Akio Yoshizawa, Mitsuko Ogata, Tohru Ishitani, Makiko Tsutsumi, Atsushi Kuroiwa, Motoyuki Itoh, Yutaka Kikuchi
- Organizer
  日本分子生物学会(招待講演)
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23616002
[Presentation] DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish.
- Author(s)
  Shunya Hozumi, Ryo Hirabayashi, Akio Yoshizawa, Mitsuko Ogata, Tohru Ishitani, Makiko Tsutsumi, Atsushi Kuroiwa, Motoyuki Itoh, Yutaka Kikuchi.
- Organizer
  10th International Conference Zebrafish Development and Genetics
- Place of Presentation
  アメリカ・ウィスコンシン
- Data Source
  KAKENHI-PROJECT-24710221
[Presentation] The DEAD-box protein Ddx46 is required for differentiation of definitive hematopietic stem cells in zebrafish
- Author(s)
  Hirabayashi, R., Hozumi, S., and Kikuchi, Y.
- Organizer
  日本分子生物学会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-23616002
[Presentation] ゼブラフィッシュにおけるDnmt4, Dnmt3aa, Dnmt3ab の発現解析
- Author(s)
  高山和也，高永俊佑，下田修義，穂積俊矢，菊池裕
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24710221
[Presentation] Ddx46 Is Required for Multi-Lineage Differentiation of Hematopoietic Stem Cells in zebrafish.
- Author(s)
  Hirabayashi, R., Hozumi, S., Higashijima, S. and Kikuchi, Y.
- Organizer
  日本発生生物学会
- Place of Presentation
  島根県
- Data Source
  KAKENHI-PROJECT-23616002
[Presentation] ターゲットオブラパマイシン複合体１（TORC1）は、ゼブラフィッシュ尾ビレ再生を制御する
- Author(s)
  廣瀬健太朗、塩見太志、穂積俊矢、菊池　裕
- Organizer
  日本動物学会
- Place of Presentation
  東北大学
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] mRNAスプライシング因子Ddx46は造血幹細胞の維持や血球分化に必要である
- Author(s)
  穂積俊矢、平林諒、東島眞一、菊池裕
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶應義塾大学日吉キャンパス
- Data Source
  KAKENHI-PROJECT-24710221
[Presentation] ゼブラフィッシュの発生・再生過程におけるマウスdnmt3相同遺伝子の発現・機能解析
- Author(s)
  髙山和也、下田修義、高永俊祐、穂積俊矢、菊池　裕
- Organizer
  日本遺伝学会
- Place of Presentation
  長浜バイオ大学
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] Mechanistic target of rapamycin complex１(mTORC1)はゼブラフィッシュ尾ビレ再生に必要である
- Author(s)
  廣瀬健太朗、塩見太志、穂積俊矢、菊池　裕
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] 遺伝子発現制御解析による細胞可塑性コントロール機構の解明
- Author(s)
  穂積俊矢、宮本　良祐、粂　昭苑、菊池　裕
- Organizer
  日本生化学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] bHLH型転写因子による神経細胞での内胚葉・中胚葉性遺伝子発現誘導機構の解明
- Author(s)
  穂積俊矢、宮本良祐、粂昭苑、菊池裕
- Organizer
  日本遺伝学会第８６回大会
- Place of Presentation
  長浜バイオ大学(滋賀県・長浜市)
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-24710221
[Presentation] 遺伝子発現制御解析による細胞可塑性コントロール機構の解明
- Author(s)
  穂積俊矢、宮本良祐、粂昭苑、菊池裕
- Organizer
  第８７回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府・京都市)
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24710221
[Presentation] 再生過程におけるマウスdnmt3相同遺伝子の発現・機能解析
- Author(s)
  髙山和也、下田修義、高永俊祐、穂積俊矢、菊池　裕
- Organizer
  日本動物学会中国四国支部
- Place of Presentation
  岡山理科大学
- Year and Date
  2014-05-10 – 2014-05-11
- Data Source
  KAKENHI-PROJECT-26430185
[Presentation] DEAD-box protein Ddx46 is required for the maintenance of hematopietic stem cells in zebrafish definitive hematopiesis
- Author(s)
  Hirabayashi, R., Hozumi, S., and Kikuchi, Y.
- Organizer
  Joint meeting of the 45th JSDB and the 64th JSCB
- Place of Presentation
  兵庫県神戸市
- Invited
- Data Source
  KAKENHI-PROJECT-23616002
[Presentation] ゼブラフィッシュ尾ビレ再生における脱分化機構の解析
- Author(s)
  菊池　裕、廣瀬健太朗、下田修義、髙山和也、塩見太志、穂積俊矢
- Organizer
  日本解剖学会
- Place of Presentation
  自治医大
- Invited
- Data Source
  KAKENHI-PROJECT-23616002

1. KIKUCHI Yutaka (20286438)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
2. Machida Masayuki (30358006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Kokubo Hiroki (10270480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 武藤彰彦 (70589366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 伊藤素行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HOZUMI Shunya 穂積 俊矢

Research Projects

Research Products

Co-Researchers

神経軸索のシナプスを介したメラノーマ細胞とがん微小環境の相互作用メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of dedifferentiation mechanism by transcriptome analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome-wide analysis of novel molecular mechanism of direct reprogramming from retinal stem cell to pancreatic cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome wide screening of genomic DNA demethylation factors by genetic method.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Histone H3 Lysine 27 Trimethylation Leads to Loss of Mesendodermal Competence During Gastrulation in Zebrafish Ectodermal Cells2017

Author(s)

Journal Title

DOI

NAID

ISSN

Data Source

[Journal Article] Expression patterns of dnmt3aa, dnmt3ab, and dnmt4 during development and fin regeneration in zebrafish.2014

Author(s)

Journal Title

Data Source

[Journal Article] Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Expression patterns of dnmt3aa, dnmt3ab, and dnmt4 during development and fin regeneration in zebrafish.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ddx46 Is Required for Multi-Lineage Differentiation of Hematopoietic Stem Cells in Zebrafish2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ddx46 Is Required for Multi-Lineage Differentiation of Hematopoietic Stem Cells in Zebrafish.2013

Author(s)

Journal Title

Data Source

[Journal Article] DEAD-Box Protein Ddx46 Is Required for the Development of the Digestive Organs and Brain in Zebrafish.2012

Author(s)

Journal Title

Data Source

[Journal Article] DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] Tumor invasion and progression are associated with cholinergic-nerves via nicotinic acetylcholine receptors2019

Author(s)

Organizer

Data Source

[Presentation] 核の移動制御を介したNodalシグナルによる内胚葉分化機構の解明2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ゼブラフィッシュ初期発生における核内F-アクチンの機能解析2016

Author(s)

HOZUMI Shunya 穂積俊矢

[Presentation] 脊椎動物の中内胚葉分離における時空間的制御機構の解析2015