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HAYASHI SANAE  林 佐奈衣

… Alternative Names

林 佐奈衣  ハヤシ サナエ

HAYASHI Sanae  林 佐奈衣

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Researcher Number 10597587
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9164-9152
Affiliation (Current) 2023: 熊本大学, 大学院生命科学研究部(医), 特任助教
Affiliation (based on the past Project Information) *help 2023: 熊本大学, その他の研究科, 助教
2021: 熊本大学, 大学院生命科学研究部(医), 学術研究員
2020: 熊本大学, 大学院生命科学研究部(医), 特定事業研究員
2016 – 2017: 名古屋市立大学, 大学院医学研究科, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords
Principal Investigator
B型肝炎ウイルス / 核酸アナログ / 肝臓学 / NK細胞 / 肝障害 / 免疫 / 炎症 / HBs抗原 / テノホビル / 変異 / 耐性 / genotype / 薬剤耐性
  • Research Projects

    (3 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (5 People)
  •  核酸アナログ耐性機序の解明及び多剤耐性HBVに有効な新規治療薬の開発Principal Investigator

    • Principal Investigator
      林 佐奈衣
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kumamoto University
  •  テノホビル(TDF)に対する新規耐性HBVの同定と耐性メカニズムの解明Principal Investigator

    • Principal Investigator
      林 佐奈衣
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kumamoto University
  •  Elucidating the mechanism of ameliorated liver disease and HBs antigen elimination by nucleos(t)ide analogs in chronic hepatitis B patientsPrincipal Investigator

    • Principal Investigator
      HAYASHI Sanae
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University

All 2022 2021 2020 2017

All Journal Article Presentation

  • [Journal Article] Droplet digital PCR assay provides intrahepatic HBV cccDNA quantification tool for clinical application.2022

    • Author(s)
      Hayashi Sanae、Isogawa Masanori、Kawashima Keigo、Ito Kyoko、Chuaypen Natthaya、Morine Yuji、Shimada Mitsuo、Higashi-Kuwata Nobuyo、Watanabe Takehisa、Tangkijvanich Pisit、Mitsuya Hiroaki、Tanaka Yasuhito
    • Journal Title

      Scientific Reports

      Volume: 12

    • DOI

      10.1038/s41598-022-05882-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08313, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-20K16996
  • [Journal Article] Identification of a novel long-acting 4’-modified nucleoside reverse transcriptase inhibitor against HBV2021

    • Author(s)
      Higashi-Kuwata Nobuyo、Hayashi Sanae、Kumamoto Hiroki、Ogata-Aoki Hiromi、Das Debananda、Venzon David、Hattori Shin-ichiro、Bulut Haydar、Hashimoto Mai、Otagiri Masaki、Takamune Nobutoki、Kishimoto Naoki、Davis David A.、Misumi Shogo、Kakuni Masakazu、Tanaka Yasuhito、Mitsuya Hiroaki
    • Journal Title

      Journal of Hepatology

      Volume: 15 Pages: 1075-1086

    • DOI

      10.1016/j.jhep.2020.12.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16996, KAKENHI-PROJECT-18K08460
  • [Journal Article] Blood-Based Biomarkers in Hepatitis B Virus-Related Hepatocellular Carcinoma, Including the Viral Genome and Glycosylated Proteins2021

    • Author(s)
      Hayashi Sanae、Nagaoka Katsuya、Tanaka Yasuhito
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Pages: 11051-11051

    • DOI

      10.3390/ijms222011051

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17403, KAKENHI-PROJECT-20K16996
  • [Presentation] In vivoで強力な抗HBV活性を発揮する長時間作用型新規核酸アナログE-CFCPの開発2021

    • Author(s)
      林 佐奈衣,田中 靖人,満屋 裕明
    • Organizer
      The Japan Society of Hepatology
    • Data Source
      KAKENHI-PROJECT-20K16996
  • [Presentation] A novel droplet digital PCR reveals the stability of intrahepatic hepatitis B virus cccDNA and its clinical application2021

    • Author(s)
      Sanae Hayashi, Masanori Isogawa, Keigo Kawashima, Kyoko Ito, Natthaya Chuaypen, Nobuyo Higashi-Kuwata, Pisit Tangkijvanich, Hiroaki Mitsuya, Yasuhito Tanaka
    • Organizer
      The Liver Meeting AASLD 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16996
  • [Presentation] 新規cccDNA絶対定量系の開発とその臨床応用2020

    • Author(s)
      Sanae Hayashi,Tangkijvanich Pisit,Yasuhito Tanaka
    • Organizer
      第56回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K16996
  • [Presentation] Novel Nucleosides, CMCP and CFCP, Potently Block the Infectivity and Replication of Wild-type and Drug-resistant HBVs in Culture and in Human-liver-chimeric Mice and Show Potential QW or Q2W.2017

    • Author(s)
      Higashi-kuwata N, Hayashi S, Kumamoto H, Kohgo S, Das D, Bulut H, Sarafianos S, Tanaka Y, Mitsuya H.
    • Organizer
      HEP DART
    • Data Source
      KAKENHI-PROJECT-16K19360
  • [Presentation] 新規4'-置換-7-デアザプリンヌクレオシド類の合成と抗HBV活性評価2017

    • Author(s)
      苫谷晃太, 大野裕太郎, 杉原匠, 山田浩平, 鍬田伸好, 林佐奈衣, 村上周子, 前田賢次, 田中靖人, 満屋裕明.
    • Organizer
      第27回抗ウイルス療法学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-16K19360
  • [Presentation] Entecavirよりも持続的かつ強力に抗HBV活性を有する新規核酸アナログCFCPの同定2017

    • Author(s)
      林佐奈衣, 鍬田伸好, 熊本浩樹, 村上周子, 尾曲克己, 五十川正記, 前田賢次, 満屋裕明, 田中靖人.
    • Organizer
      第27回抗ウイルス療法学会学術集会・総会.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19360
  • [Presentation] 新規抗HBV薬候補化合物CFCPのin vitroウイルス学・細胞生物学的特性2017

    • Author(s)
      鍬田伸好, 林佐奈衣, 熊本浩樹, 服部真一朗, 橋本麻衣, 林宏典, 松田幸樹, 青木学, 前田賢次, 小田切優樹, 田中靖人, 満屋裕明.
    • Organizer
      第27回抗ウイルス療法学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-16K19360
  • 1.  ISOGAWA Masanori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  TANAKA Yasuhito
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  WATANABE Takehisa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  NAGAOKA KATSUYA
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  東 伸好
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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