Okada Toshiyuki 岡田季之

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OKADA Toshiyuki 岡田季之

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Researcher Number	10607328
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 久留米大学, 医学部, 助教 2016 – 2018: 久留米大学, 医学部, 助教 2015: 国立研究開発法人国立国際医療研究センター, 研究所, 研究員 2015: 国立国際医療研究センター, 研究所, 研究員 2014: 国立研究開発法人国立国際医療研究センター, 研究所, 流動研究員 2013: 独立行政法人国立国際医療研究センター, 研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Immunology
Keywords	Principal Investigator AICDA / AID / 異所性発現 / 炎症性腸疾患 / 慢性炎症 / 大腸炎関連がん / CAC / inflammation / colonic epithelial cells / ectopic expression … More / 大腸炎 / 細胞外マトリックス / 上皮再生 / 大腸上皮細胞 / DSS / メチル化 / クローン病 / DNAメチル化 / エピジェネティクス / 活性化誘導シチジンデアミナーゼ / 胆汁酸 … More Except Principal Investigator 制御性T細胞 / 免疫学 / Grb2 / Themis / 核 / シグナル伝達 / TCR / 胸腺 / T細胞 Less

慢性炎症環境に大腸陰窩が適応するためのAIDによる変異獲得メカニズムの解明Principal Investigator
- Principal Investigator
  
  岡田季之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
Novel function "regulation of extracellular matrix construction" of ectopic AID expression in wound healing process.Principal Investigator
- Principal Investigator
  
  Okada Toshiyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
Role of epigenetic modification by bile acidPrincipal Investigator
- Principal Investigator
  
  Okada Toshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Studies on nuclear signaling proteins required for T cell development
- Principal Investigator
  
  Nitta Takeshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
  独立行政法人国立国際医療研究センター

All 2023 2022 2021 2020 2018 2015 2014 Other

All Journal Article Presentation Book

[Book] 消化器病学サイエンス 5(2) 初心者でもわかるゲノム編集技術2021
- Author(s)
  岡田季之、皆川貴範、溝口恵美子
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-20K08318
[Journal Article] Landscape of inflammatory bowel disease in Singapore2022
- Author(s)
  Low Daren、Swarup Nidhi、Okada Toshiyuki、Mizoguchi Emiko
- Journal Title
  
  Intestinal Research
  
  Volume: 2021.00089. Issue: 3 Pages: 00089-00089
- DOI
  10.5217/ir.2021.00089
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08318, KAKENHI-PROJECT-21K07996
[Journal Article] Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell Adhesion Molecule 6, and Ectopic Claudin-2 in the Carcinogenic Processes of Ulcerative Colitis2022
- Author(s)
  KINUGASA TETSUSHI、TSUNODA TOSHIYUKI、MIZOGUCHI EMIKO、OKADA TOSHIYUKI、SUDO TOMOYA、KAWAHARA AKIHIKO、AKIBA JUN、AKAGI YOSHITO
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 8 Pages: 4119-4127
- DOI
  10.21873/anticanres.15910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08318, KAKENHI-PROJECT-20K09114
[Journal Article] A Review of Selected IBD Biomarkers: From Animal Models to Bedside2021
- Author(s)
  Emiko Mizoguchi, Renuka Subramaniam, Toshiyuki Okada, and Atsushi Mizoguchi
- Journal Title
  
  Diagnostics
  
  Volume: 11 Issue: 2 Pages: 207-207
- DOI
  10.3390/diagnostics11020207
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08318, KAKENHI-PROJECT-21K07996, KAKENHI-PROJECT-18K07987
[Journal Article] Biological Analyses-Derived Translational Findings in the T Cell Receptor Alpha Chain Knockout Mouse as an Experimental Model for Ulcerative Colitis2021
- Author(s)
  Mizoguchi Emiko、Sadanaga Takayuki、Okada Toshiyuki
- Journal Title
  
  International Journal of Translational Medicine
  
  Volume: 1 Issue: 3 Pages: 187-204
- DOI
  10.3390/ijtm1030014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08318, KAKENHI-PROJECT-21K07996
[Journal Article] Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models2020
- Author(s)
  Emiko Mizoguchi, Daren Low, Yui Ezaki, and Toshiyuki Okada
- Journal Title
  
  Intestinal Research
  
  Volume: 18 Issue: 2 Pages: 151-167
- DOI
  10.5217/ir.2019.09154
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08318
[Journal Article] Rasal3-mediated T cell survival is essential for inflammatory responses2018
- Author(s)
  Muro Ryunosuke、Nitta Takeshi、Kitajima Masayuki、Okada Toshiyuki、Suzuki Harumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 496 Issue: 1 Pages: 25-30
- DOI
  10.1016/j.bbrc.2017.12.159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08803, KAKENHI-PROJECT-16K19102, KAKENHI-PROJECT-16K19375, KAKENHI-PROJECT-16H05202, KAKENHI-PROJECT-15H05703
[Journal Article] The Ras GTPase-activating protein Rasal3 supports survival of naïve T cells.2015
- Author(s)
  Muro R, Nitta T, Okada T, Ideta H, Tsubata T, Suzuki H
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0119898-e0119898
- DOI
  10.1371/journal.pone.0119898
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25111516, KAKENHI-PROJECT-25460606, KAKENHI-PROJECT-26293062
[Journal Article] Differential Function of Themis CABIT Domains during T Cell Development.2014
- Author(s)
  Okada T, Nitta T, Kaji K, Takashima A, Oda H, Tamehiro N, Goto M, Okamura T, Patrick MS, Suzuki H.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 2 Pages: e89115-e89115
- DOI
  10.1371/journal.pone.0089115
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790491, KAKENHI-PROJECT-25460606, KAKENHI-PROJECT-25871164
[Presentation] Loss of AID expression under inflammatory condition alters the Nid1 and Fbln2 induction and exacerbates intestinal injury2023
- Author(s)
  Toshiyuki Okada, Yusuke Toyoda, Takayuki Sadanaga, Tomoi Noda, Risako Onitsuka, Atsushi Mizoguchi, Emiko Mizoguchi, Shigeaki Saitoh
- Organizer
  Japanese society for Immunology 2023
- Data Source
  KAKENHI-PROJECT-23K07384
[Presentation] 炎症により大腸上皮細胞に異所性発現するAIDは、DNAの脱メチル化を引き起こすことで標的遺伝子の発現に影響を与える2023
- Author(s)
  岡田季之、豊田雄介、溝口充志、齋藤成昭
- Organizer
  分子生物学会2023
- Data Source
  KAKENHI-PROJECT-23K07384
[Presentation] Themis regulates CD8-dependent contact hyper sensitivity2023
- Author(s)
  Masayuki Kitajima, Toshiyuki Okada, and Harumi Suzuki
- Organizer
  Japanese society for Immunology 2023
- Data Source
  KAKENHI-PROJECT-23K07384
[Presentation] Themis in peripheral CD8 T cells regulates hapten-induced allergic skin inflammation2022
- Author(s)
  Masayuki Kitajima, Toshiyuki Okada, Harumi Suzuki.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08318
[Presentation] Role of a putative cyclin-binding domain in one of the nuclear localization sequences of Chitinase 3-like 1 in colonic epithelial cells2021
- Author(s)
  Emiko Mizoguchi, Toshiyuki Okada, Takanori Minagawa, Chun-Geun Lee, Jack A. Elia, Atsushi Mizoguchi.
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-20K08318
[Presentation] 大腸炎によって異所性発現するAIDの役割2020
- Author(s)
  岡田季之、溝口充志、溝口恵美子、齋藤成昭
- Organizer
  第57回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K08318
[Presentation] 口腔扁平上皮発癌におけるChitinase 3-like 1 の関与2020
- Author(s)
  寺谷由唯、楠川仁悟、岡田季之、溝口充志、溝口恵美子
- Organizer
  第57回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K08318
[Presentation] Themis is important for differentiation of regulatory T cells2014
- Author(s)
  Toshiyuki Okada, Takeshi Nitta, Masayuki Kitajima, Hiroyo Oda, Harumi Suzuki
- Organizer
  第４３回日本免疫学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25460606
[Presentation] Differential function of two CABIT domains in Themis
- Author(s)
  Toshiyuki Okada, Takeshi Nitta, Hiroyo Oda, Michael Scott Patrick, Harumi Suzuki
- Organizer
  日本免疫学会総会・学術集会 2013
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-25460606
[Presentation] Themis regulates cytokine production in mature naïve T cells
- Author(s)
  Toshiyuki Okada, Takeshi Nitta, Norimasa Tamehiro, Patrick Michael, Harumi Suzuki
- Organizer
  ThymOz International Conference
- Place of Presentation
  Heron Island, Queensland, Australia
- Year and Date
  2014-04-02 – 2014-04-07
- Data Source
  KAKENHI-PROJECT-25460606

1. Nitta Takeshi (30373343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. TAMEHIRO Norimasa (80597881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 溝口恵美子 (40782157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 長澤丘司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 北島雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okada Toshiyuki 岡田 季之

OKADA Toshiyuki 岡田 季之

Research Projects

Research Products

Co-Researchers

慢性炎症環境に大腸陰窩が適応するためのAIDによる変異獲得メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel function "regulation of extracellular matrix construction" of ectopic AID expression in wound healing process.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of epigenetic modification by bile acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on nuclear signaling proteins required for T cell development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 消化器病学サイエンス 5(2) 初心者でもわかるゲノム編集技術2021

Author(s)

Publisher

Data Source

[Journal Article] Landscape of inflammatory bowel disease in Singapore2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell Adhesion Molecule 6, and Ectopic Claudin-2 in the Carcinogenic Processes of Ulcerative Colitis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Review of Selected IBD Biomarkers: From Animal Models to Bedside2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biological Analyses-Derived Translational Findings in the T Cell Receptor Alpha Chain Knockout Mouse as an Experimental Model for Ulcerative Colitis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rasal3-mediated T cell survival is essential for inflammatory responses2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Ras GTPase-activating protein Rasal3 supports survival of naïve T cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential Function of Themis CABIT Domains during T Cell Development.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Loss of AID expression under inflammatory condition alters the Nid1 and Fbln2 induction and exacerbates intestinal injury2023

Author(s)

Organizer

Data Source

[Presentation] 炎症により大腸上皮細胞に異所性発現するAIDは、DNAの脱メチル化を引き起こすことで標的遺伝子の発現に影響を与える2023

Author(s)

Organizer

Okada Toshiyuki 岡田季之

OKADA Toshiyuki 岡田季之