YAMAMOTO KEISUKE 山本恵介

… Alternative Names

山本恵介ヤマモトケイスケ

YAMAMOTO Keisuke 山本恵介

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Researcher Number	10608532
Other IDs
Affiliation (Current)	2023: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2022: 東京大学, 医学部附属病院, 助教 2015 – 2017: 東京大学, 医学部附属病院, 助教 2014 – 2015: 東京大学, 医学部附属病院, 特任臨床医 2012 – 2013: 東京大学, 医学部附属病院, その他
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 膵癌 / エピジェネティクス / セリン生合成経路 / ヒストン修飾 / 癌微小環境 / 癌関連線維芽細胞 / アミノ酸代謝 / 合成致死 / 肝転移 / 代謝 … More Except Principal Investigator … More 膵癌 / KDM6B / 膵がん / エピジェネテイクス / クロマチン Less

セリン生合成経路に着目した膵癌に対する合成致死治療法の開発Principal Investigator
- Principal Investigator
  
  山本恵介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Analysis of chromatin structure for targeting pancreatic cancer
- Principal Investigator
  
  立石敬介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  St. Marianna University School of Medicine
肝細胞におけるセリン生合成経路を標的とした膵がん肝転移治療法開発の試みPrincipal Investigator
- Principal Investigator
  
  山本恵介
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  The University of Tokyo
患者由来膵癌異種移植腫瘍を用いたエピジェネティック因子を標的とした新規治療の開発Principal Investigator
- Principal Investigator
  
  山本恵介
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Identification of a molecular marker relating to the progression of pancreatic cancer cells
- Principal Investigator
  
  Nakai Yousuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
An investigation of histone modifications that modulate malignant properties of pancreatic cancer.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Keisuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Thromboembolisms in Advanced Pancreatic Cancer: A Retrospective Analysis of 475 Patients2017
- Author(s)
  Ishigaki K(1), Nakai Y, Isayama H, Saito K, Hamada T, Takahara N, Mizuno S, Mohri D, Kogure H, Matsubara S, Yamamoto N, Tada M, Koike K.
- Journal Title
  
  Pancreas
  
  Volume: 46 Pages: 1069-1075
- DOI
  10.1097/mpa.0000000000000889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09038, KAKENHI-PROJECT-15K09042
[Journal Article] The Role of Pancreatic Enzyme Replacement Therapy in Unresectable Pancreatic Cancer: A Prospective CohortStudy2017
- Author(s)
  Saito T, Hirano K, Isayama H, Nakai Y, Saito K, Umefune G, Akiyama D, Watanabe T, Takagi K, Hamada T, Takahara N, Uchino R, Mizuno S, Kogure H, Matsubara S, Yamamoto N, Tada M, Koike K.
- Journal Title
  
  Dig Endosc
  
  Volume: 46 Pages: 341-346
- DOI
  10.1097/mpa.0000000000000767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09042
[Journal Article] Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.2016
- Author(s)
  Yamamoto K, Tateishi K, Kudo Y, Hoshikawa M, Tanaka M, Nakatsuka T, Fujiwara H, Miyabayashi K, Takahashi R, Tanaka Y, Ijichi H, Nakai Y,Isayama H, Morishita Y, Aoki T, Sakamoto Y, Hasegawa K, Kokudo N, Fukayama M, Koike K.
- Journal Title
  
  Oncotarget.
  
  Volume: 7 Pages: 61469-61484
- DOI
  10.18632/oncotarget.11129
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09040, KAKENHI-PROJECT-26460985
[Journal Article] The inhibition of renin-angiotensin system in advanced pancreatic cancer: an exploratory analysis in 349 patients2015
- Author(s)
  Nakai Y, Isayama H, Sasaki T, Takahara N, Saito K, Ishigaki K, Hamada T, Mizuno S, Miyabayashi K, Yamamoto K, Mohri D, Kogure H, Yamamoto N, Ijichi H, Tateishi K, Tada M, Koike K.
- Journal Title
  
  J Cancer Res Clin Oncol.
  
  Volume: 144 Pages: 933-939
- DOI
  10.1007/s00432-014-1873-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09042
[Journal Article] Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα2014
- Author(s)
  Yamamoto K, Tateishi K, Kudo Y, Sato T, Yamamoto S, Miyabayashi K, Asaoka Y, Ijichi H, Hirata Y, Otsuka M, Nakai Y, Isayama H, Ikenoue T, Kurokawa M, Fukayama M, Kokudo N, Omata M and Koike K.
- Journal Title
  
  Carcinogenesis.
  
  Volume: 35 Pages: 2404-14
- DOI
  10.1093/carcin/bgu136
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590932, KAKENHI-PROJECT-24591009, KAKENHI-PROJECT-26460985, KAKENHI-PROJECT-26461031, KAKENHI-PROJECT-26860257
[Presentation] Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer2016
- Author(s)
  Keisuke Yamamoto, Keisuke Tateishi, Mayumi Hoshikawa, Mariko Tanaka, Koji Miyabayashi, Ryota Takahashi, Hideaki Ijichi, Yosuke Nakai, Hiroyuki Isayama, Minoru Tada, Taku Aoki, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo, Masashi Fukayama, Kazuhiko Koike
- Organizer
  第47回日本膵臓学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-08-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09040
[Presentation] Epigenetic remodeling of cancer-associated fibroblasts through BET inhibition suppresses pancreatic cancer progression2016
- Author(s)
  Keisuke Yamamoto, Keisuke Tateishi, Takuma Nakatsuka, Yasuo Tanaka, Hideaki Ijichi, Norihiro Kokudo, Masashi Fukayama, Kazuhiko Koike
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09040
[Presentation] 臨床検体を用いた膵癌xenograft モデルの樹立とその応用2016
- Author(s)
  山本恵介, 立石敬介, 小池和彦
- Organizer
  第１０２回　日本消化器病学会総会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K09040
[Presentation] Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.2016
- Author(s)
  Keisuke Yamamoto, Keisuke Tateishi, Yotaro Kudo, Mayumi Hoshikawa, Mariko Tanaka, Hideaki Ijichi, Yousuke Nakai, Hiroyuki Isayama, Yasuyuki Morishita, Taku Aoki, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo, Masashi Fukayama, and Kazuhiko Koike
- Organizer
  AACR 2016, Special conference on pancreatic cancer
- Place of Presentation
  JW Marriott Orlando Grande Lakes in Orlando, FL.
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09040
[Presentation] Reduced expression of histone demethylase KDM6B promotes pancreatic cancer progression through downregulation of C/EBPα.2013
- Author(s)
  山本　恵介
- Organizer
  American Association of Cancer Research Annual Meeting 2013
- Place of Presentation
  Washingto, DC
- Data Source
  KAKENHI-PROJECT-24591009
[Presentation] ヒストン脱メチル化酵素KDM6Bの発現低下はCEBPAの発現低下を介し膵癌の進展を促進する
- Author(s)
  山本恵介、立石敬介、工藤洋太郎、佐藤智彦、松坂恵介、山本信三、宮林弘至、浅岡良成、伊地知秀明、中井陽介、伊佐山浩通、池上恒雄、黒川峰夫、深山正久、國土典宏、小俣政男、小池和彦
- Organizer
  第４５回大会　日本膵臓学会大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2014-07-11 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-24591009

1. TATEISHI Keisuke (20396948)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. IJICHI Hideaki (70463841)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. Nakai Yousuke (80466755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 松原三郎 (40750550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 工藤洋太郎 (90608358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKENOUE Tsuneo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. MATSUSAKA Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. TANAKA Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 建石良介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 山本夏代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAMOTO KEISUKE 山本 恵介

山本 恵介 ヤマモト ケイスケ

YAMAMOTO Keisuke 山本 恵介

Research Projects

Research Products

Co-Researchers

セリン生合成経路に着目した膵癌に対する合成致死治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of chromatin structure for targeting pancreatic cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝細胞におけるセリン生合成経路を標的とした膵がん肝転移治療法開発の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

患者由来膵癌異種移植腫瘍を用いたエピジェネティック因子を標的とした新規治療の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of a molecular marker relating to the progression of pancreatic cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An investigation of histone modifications that modulate malignant properties of pancreatic cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Thromboembolisms in Advanced Pancreatic Cancer: A Retrospective Analysis of 475 Patients2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Role of Pancreatic Enzyme Replacement Therapy in Unresectable Pancreatic Cancer: A Prospective CohortStudy2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The inhibition of renin-angiotensin system in advanced pancreatic cancer: an exploratory analysis in 349 patients2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Epigenetic remodeling of cancer-associated fibroblasts through BET inhibition suppresses pancreatic cancer progression2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 臨床検体を用いた膵癌xenograft モデルの樹立とその応用2016

YAMAMOTO KEISUKE 山本恵介

山本恵介ヤマモトケイスケ

YAMAMOTO Keisuke 山本恵介