SAKAI Yusuke 堺裕輔

Researcher Number	10608904
Other IDs
External Links
Affiliation (Current)	2022: 九州大学, 工学研究院, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 九州大学, 工学研究院, 助教 2014 – 2018: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2015: 長崎大学, 医歯薬学総合研究科 (医学系), 助教 2013: 長崎大学, 医歯(薬)学総合研究科, 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / General surgery / Biomedical engineering/Biomaterial science and engineering / Basic Section 90110:Biomedical engineering-related Except Principal Investigator General surgery / Digestive surgery / Biomedical engineering/Biomaterial science and engineering / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 肝細胞 / 再生医療 / 肝臓 / 細胞シート / 血管新生 / 内皮細胞 / 胆管 / 肝再生医療 / アレイ化 / 管腔 … More / 肝毛細胆管 / リプログラミング / 肝内胆管 / 類洞 / ECM / 構造タンパク質 / スポンジ / ニードル … More Except Principal Investigator 再生医療 / 細胞シート / 肝細胞 / 肝臓 / ヒト / 移植 / 脂肪組織由来多能性幹細胞 / 肝放射線照射 / 増殖刺激 / 脂肪由来幹細胞 / 急性肝不全 / 肝移植 / 胆道合併症 / 肝臓外科 / 3Dプリンター / 細胞工学 / 胆管 / 胆管狭窄 / 胆管合併症 / 組織工学 / 胆管上皮細胞 / 3D培養 / 人工胆管 / 生体吸収材料 / 細胞治療 / 筋芽細胞 / 括約筋 / 消化管再生 Less

Fabrication of detachable-liver based on liver-derived ECM sponge needlePrincipal Investigator
- Principal Investigator
  
  堺裕輔
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyushu University
Fabrication of bioengineered sphincter construct with myoblast sheet
- Principal Investigator
  
  金高賢悟
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nagasaki University
Reconstruction of liver from arranged-hepatocytes/liver sinusoidal endothelial cells/cholangiocytes tissuesPrincipal Investigator
- Principal Investigator
  
  SAKAI Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyushu University
In vitro reconstruction of functional bile canaliculus-intrahepatic bile duct structurePrincipal Investigator
- Principal Investigator
  
  SAKAI Yusuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyushu University
  Nagasaki University
Fabrication of human liver with mimicking hepatic lobule structures by alternately-arranged human hepatocyte/endotherial cell tissue transplantationPrincipal Investigator
- Principal Investigator
  
  SAKAI Yusuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Nagasaki University
Prevention of postoperative biliary stricture by application of hybrid bioartificial bile duct
- Principal Investigator
  
  SOYAMA Akihiko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Nagasaki University
Acute liver failure treatment using rapid fabricated engineered hepatocyte sheets
- Principal Investigator
  
  EGUCHI Susumu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nagasaki University
Construction of liver tissue in vivo with preparative partial hepatic irradiation and growth stimulus: investigations of less invasive techniques and progenitor cells.
- Principal Investigator
  
  YAMANOUCHI Kosho
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagasaki University
Construction of vascularized ectopic liver tissue from engineered human hepatocyte sheetPrincipal Investigator
- Principal Investigator
  
  SAKAI Yusuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Nagasaki University
Reconstruction of human liver sheet for preclinical study of liver regenerative medicine
- Principal Investigator
  
  EGUCHI Susumu
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nagasaki University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] 再生医療用語ハンドブック：　肝細胞移植2015
- Author(s)
  堺裕輔、江口晋
- Total Pages
  1
- Publisher
  株式会社メディカルトリビューン
- Data Source
  KAKENHI-PROJECT-25861161
[Journal Article] Successful induction of human chemically induced liver progenitors with small molecules from damaged liver2022
- Author(s)
  Miyoshi Takayuki、Hidaka Masaaki、Miyamoto Daisuke、Sakai Yusuke、Murakami Shunsuke、Huang Yu、Hara Takanobu、Soyama Akihiko、Kanetaka Kengo、Ochiya Takahiro、Eguchi Susumu
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: -
- DOI
  10.1007/s00535-022-01869-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04445
[Journal Article] Bioengineering of a CLiP‐derived tubular biliary‐duct‐like structure for bile transport in vitro2021
- Author(s)
  Huang Yu、Sakai Yusuke、Hara Takanobu、Katsuda Takeshi、Ochiya Takahiro、Gu Wei‐Li、Miyamoto Daisuke、Hamada Takashi、Hidaka Masaaki、Eguchi Susumu、Kanetaka Kengo、Adachi Tomohiko
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: － Pages: 2572-2584
- DOI
  10.1002/bit.27773
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932, KAKENHI-PROJECT-19H04445
[Journal Article] Functional changes of cocultured hepatocyte sheets subjected to continuous liver regeneration stimulation in cDNA-uPA/SCID mouse: Differences in transplantation sites2021
- Author(s)
  Miyamoto Daisuke、Sakai Yusuke、Huang Yu、Yamasaki Chihiro、Tateno Chise、Hasegawa Hideko、Murai Tomomi、Hara Takanobu、Adachi Tomohiko、Soyama Akihiko、Hidaka Masaaki、Ito Shinichiro、Kanetaka Kengo、Eguchi Susumu
- Journal Title
  
  Regenerative Therapy
  
  Volume: 18 Pages: 7-11
- DOI
  10.1016/j.reth.2021.02.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04445
[Journal Article] Chemical conversion of aged hepatocytes into bipotent liver progenitor cells2021
- Author(s)
  Huang Yu、Miyamoto Daisuke、Li Pei‐Lin、Sakai Yusuke、Hara Takanobu、Adachi Tomohiko、Soyama Akihiko、Hidaka Masaaki、Kanetaka Kengo、Gu Wei‐Li、Eguchi Susumu
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Pages: 323-335
- DOI
  10.1111/hepr.13609
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932, KAKENHI-PROJECT-19H04445
[Journal Article] Highly feasible procedure for laparoscopic transplantation of cell sheets under pneumoperitoneum in porcine model2021
- Author(s)
  Yamaguchi Shun、Kanetaka Kengo、Maruya Yasuhiro、Higashi Miki、Kobayashi Shinichiro、Hashiguchi Keiichi、Oohashi Fumiya、Sakai Yusuke、Nakao Kazuhiko、Eguchi Susumu
- Journal Title
  
  Surgical Endoscopy
  
  Volume: －
- DOI
  10.1007/s00464-021-08708-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16368, KAKENHI-PROJECT-19H04445
[Journal Article] Bile duct reconstruction using scaffold-free tubular constructs created by Bio-3D printer2021
- Author(s)
  Takashi Hamada, Anna Nakamura, Akihiko Soyama, Yusuke Sakai, Takayuki Miyoshi, Shun Yamaguchi, Masaaki Hidaka, Takanobu Hara, Tota Kugiyama, Mitsuhisa Takatsuki, Akihide Kamiya, Koichi Nakayama, Susumu Eguchi.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 16 Pages: 81-89
- DOI
  10.1016/j.reth.2021.02.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23609, KAKENHI-PROJECT-19H04445, KAKENHI-PUBLICLY-20H04931, KAKENHI-PROJECT-19H03643
[Journal Article] Differentiation of chemically induced liver progenitor cells to cholangiocytes: Investigation of the optimal conditions2020
- Author(s)
  Huang Yu、Sakai Yusuke、Hara Takanobu、Katsuda Takeshi、Ochiya Takahiro、Gu Wei-Li、Miyamoto Daisuke、Hamada Takashi、Kanetaka Kengo、Adachi Tomohiko、Eguchi Susumu
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 130 Issue: 5 Pages: 545-552
- DOI
  10.1016/j.jbiosc.2020.07.009
- NAID
  40022414313
- ISSN
  1389-1723
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932, KAKENHI-PROJECT-19H04445
[Journal Article] The Relationship Between Lymphangiogenesis and Liver Regeneration After Partial Hepatectomy in Cholestatic Mice2020
- Author(s)
  Hamada Takashi、Hidaka Masaaki、Takatsuki Mitsuhisa、Sakai Yusuke、Yu Haung、Natsuda Koji、Ono Shinichiro、Adachi Tomohiko、Soyama Akihiko、Eguchi Susumu
- Journal Title
  
  Lymphatic Research and Biology
  
  Volume: 18 Pages: 322-328
- DOI
  10.1089/lrb.2019.0068
- NAID
  120006988539
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04445
[Journal Article] Role of HGF for reprogramming human liver progenitor cells: Non-essential but stimulative supplement2019
- Author(s)
  Huang Yu、Miyoshi Takayuki、Sakai Yusuke、Hara Takanobu、Gu Wei-li、Eguchi Susumu
- Journal Title
  
  Journal of Hepatology
  
  Volume: 71 Pages: 438-439
- DOI
  10.1016/j.jhep.2019.03.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932
[Journal Article] Development of Bifunctional Three-Dimensional Cysts from Chemically Induced Liver Progenitors2019
- Author(s)
  Huang Yu、Sakai Yusuke、Hara Takanobu、Katsuda Takeshi、Ochiya Takahiro、Adachi Tomohiko、Hidaka Masaaki、Gu Wei-Li、Eguchi Susumu
- Journal Title
  
  Stem Cells International
  
  Volume: 2019 Pages: 1-13
- DOI
  10.1155/2019/3975689
- NAID
  120006988396
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932
[Journal Article] Time‐dependent structural and functional characterization of subcutaneous human liver tissue2018
- Author(s)
  Sakai Yusuke、Koike Makiko、Yamanouchi Kosho、Soyama Akihiko、Hidaka Masaaki、Kuroki Tamotsu、Eguchi Susumu
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 12 Pages: 2287-2298
- DOI
  10.1002/term.2761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19932, KAKENHI-PROJECT-16H05908
[Journal Article] An engineered cell sheet composed of human islets and human fibroblast, bone marrow?derived mesenchymal stem cells, or adipose?derived mesenchymal stem cells: An in vitro comparison study2018
- Author(s)
  Imamura Hajime、Adachi Tomohiko、Kin Tatsuya、Ono Shinichiro、Sakai Yusuke、Adachi Toshiyuki、Soyama Akihiko、Hidaka Masaaki、Takatsuki Mitsuhisa、Shapiro A.M. James、Eguchi Susumu
- Journal Title
  
  Islets
  
  Volume: 10
- DOI
  10.1080/19382014.2018.1445948
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932, KAKENHI-PROJECT-16H05908
[Journal Article] In vivo construction of liver tissue by implantation of a hepatic non-parenchymal/adipose-derived stem cell sheet.2018
- Author(s)
  Mio Fujii, Kosho Yamanouchi, Yusuke Sakai, Zhassulan Baimakhanov, Izumi Yamaguchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Susumu Eguchi
- Journal Title
  
  J Tissue Eng Regen Med.
  
  Volume: 印刷中
- DOI
  10.1002/term.2424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461916, KAKENHI-PROJECT-26861087, KAKENHI-PROJECT-16H05908
[Journal Article] Controlled cell morphology and liver-specific function of engineered primary hepatocytes by fibroblast layer cell densities2018
- Author(s)
  Sakai Yusuke、Koike Makiko、Kawahara Daisuke、Hasegawa Hideko、Murai Tomomi、Yamanouchi Kosho、Soyama Akihiko、Hidaka Masaaki、Takatsuki Mitsuhisa、Fujita Fumihiko、Kuroki Tamotsu、Eguchi Susumu
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 印刷中 Issue: 2 Pages: 249-257
- DOI
  10.1016/j.jbiosc.2018.02.006
- NAID
  40021645454
- ISSN
  1389-1723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05908, KAKENHI-PROJECT-26461916
[Journal Article] Tissue Repair Promotion and Functional Tissue Fabrication of Digestive Organ by Cell Sheets2018
- Author(s)
  堺裕輔、江口晋
- Journal Title
  
  MEMBRANE
  
  Volume: 43 Issue: 2 Pages: 34-39
- DOI
  10.5360/membrane.43.34
- NAID
  130006638816
- ISSN
  0385-1036, 1884-6440
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-16H05908, KAKENHI-PROJECT-26461916
[Journal Article] Spontaneous hepatocyte migration towards an endothelial cell tube network2018
- Author(s)
  Baimakhanov Zhassulan、Sakai Yusuke、Yamanouchi Kosho、Hidaka Masaaki、Soyama Akihiko、Takatsuki Mitsuhisa、Eguchi Susumu
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 12
- DOI
  10.1002/term.2577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05908, KAKENHI-PROJECT-26461916
[Journal Article] 細胞を用いた肝再生医療の最前線2017
- Author(s)
  岡田尚子、堺裕輔、江口晋
- Journal Title
  
  PHARMSTAGE
  
  Volume: 17 Pages: 10-16
- Data Source
  KAKENHI-PROJECT-26461916
[Journal Article] Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice.2017
- Author(s)
  Ikuko Takahara, Yuko Akazawa, Maiko Tabuchi, Katsuya Matsuda, Hisamitsu Miyaaki, Youko Kido, Yasuko Kanda, Naota Taura, Ken Ohnita, Fuminao Takeshima, Yusuke Sakai, Susumu Egushi, Masahiro Nakashima, Kazuhiko Nakao
- Journal Title
  
  PLOS ONE
  
  Volume: 12
- DOI
  10.1371/journal.pone.0170591
- NAID
  120006987538
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05908, KAKENHI-PROJECT-16K09362, KAKENHI-PROJECT-26461916, KAKENHI-PROJECT-16K08714
[Journal Article] 細胞を用いた肝再生医療の最前線2017
- Author(s)
  岡田尚子、堺裕輔、江口晋
- Journal Title
  
  PHARMSTAGE
  
  Volume: 17 Pages: 10-16
- Data Source
  KAKENHI-PROJECT-16H05908
[Journal Article] Up-regulated extracellular matrix components and inflammatory chemokines may impair the regeneration of cholestatic liver.2016
- Author(s)
  Shuai Zhang, Tao-Sheng Li, Akihiko Soyama, Takayuki Tanaka, Chen Yan, Yusuke Sakai, Masaaki Hidaka, Ayaka Kinoshita, Koji Natsuda, Mio Fujii, Tota Kugiyama, Zhassulan Baimakhanov, Tamotsu Kuroki, Weili Gu, Susumu Eguchi
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 26540-26540
- DOI
  10.1038/srep26540
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05908, KAKENHI-PROJECT-15K01295, KAKENHI-PROJECT-26461916, KAKENHI-PROJECT-15K15509, KAKENHI-PROJECT-26861087
[Journal Article] Efficacy of Multilayered Hepatocyte Sheet Transplantation for Radiation-Induced Liver Damage and Partial Hepatectomy in a Rat Model.2016
- Author(s)
  Zhassulan Baimakhanov, Kosho Yamanouchi, Yusuke Sakai, Makiko Koike, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Fumihiko Fujita, Kengo Kanetaka, Tamotsu Kuroki, Susumu Eguchi
- Journal Title
  
  Cell Transplant.
  
  Volume: 25 Pages: 549-558
- DOI
  10.3727/096368915x688669
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461916, KAKENHI-PROJECT-26861087, KAKENHI-PROJECT-25462097
[Journal Article] Equal distribution of mesenchymal stem cells after hepatic ischemia-reperfusion injury.2016
- Author(s)
  Askhat Isbambetov, Zhassulan Baimakhanov, Akihiko Soyama, Masaaki Hidaka, Yusuke Sakai, Mitsuhisa Takatsuki, Tamotsu Kuroki, Susumu Eguchi
- Journal Title
  
  J Surg Res.
  
  Volume: 203 Pages: 360-367
- DOI
  10.1016/j.jss.2016.03.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05908, KAKENHI-PROJECT-26461916, KAKENHI-PROJECT-26861087
[Journal Article] 組織工学による低侵襲な肝疾患治療2015
- Author(s)
  堺裕輔、江口晋
- Journal Title
  
  細胞
  
  Volume: 47 Pages: 18-21
- Data Source
  KAKENHI-PROJECT-26461916
[Journal Article] Vascularized subcutaneous human liver tissue from engineered hepatocyte/fibroblast sheets in mice.2015
- Author(s)
  Yusuke Sakai, Kosho Yamanouchi, Kazuo Ohashi, Makiko Koike, Rie Utoh, Hideko Hasegawa, Izumi Muraoka, Takashi Suematsu, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Susumu Eguchi
- Journal Title
  
  Biomaterials.
  
  Volume: 65 Pages: 66-75
- DOI
  10.1016/j.biomaterials.2015.06.046
- NAID
  120006986875
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461916, KAKENHI-PROJECT-26861087, KAKENHI-PROJECT-26670587
[Journal Article] Rapid production of engineered human primary hepatocyte/fibroblast sheets.2015
- Author(s)
  Yusuke Sakai, Makiko Koike, Akihiko Soyama, Masaaki Hidaka, Tamotsu Kuroki, Susumu Eguchi
- Journal Title
  
  Data Brief.
  
  Volume: 5 Pages: 498-501
- DOI
  10.1016/j.dib.2015.09.044
- NAID
  120006986862
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461916, KAKENHI-PROJECT-26861087
[Journal Article] Efficacy of multi-layered hepatocyte sheet transplantation for radiation-induced liver damage and partial hepatectomy in a rat model2015
- Author(s)
  Zhassulan Baimakhanov, Kosho Yamanouchi, Yusuke Sakai, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Fumihiko Fujita, Kengo Kanetaka, Tamotsu Kuroki, Susumu Eguchi
- Journal Title
  
  Journal of the American College of Surgeons
  
  Volume: 221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461916
[Journal Article] Rapid fabrication of engineered liver tissue using novel fibroblast system2014
- Author(s)
  Yusuke Sakai, Makiko Koike, Hideko Hasegawa, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Teruo Okano, and Susumu Eguchi
- Journal Title
  
  ALTEX Proceedings
  
  Volume: 3 Pages: 44-44
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591868
[Journal Article] Micropatterned culture of HepG2 spheroids using microwell chip with honeycomb-patterned polymer film2014
- Author(s)
  Hidekazu Yamazaki, Shun Goto, Koju Ito, Souichi Kohashi, Yuki Goto, Yukiko Yoshiura, Yusuke Sakai, Hiroshi Yabu, Masatsugu Shimomura, and Kohji Nakazawa
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 118 Issue: 4 Pages: 455-460
- DOI
  10.1016/j.jbiosc.2014.03.006
- NAID
  110009865430
- ISSN
  1389-1723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861161
[Journal Article] Detachably assembled microfluidic device for perfusion culture and post-culture analysis of a spheroid array2014
- Author(s)
  Yusuke Sakai, Koji Hattori, Fumiki Yanagawa, Shinji Sugiura, Toshiyuki Kanamori, and Kohji Nakazawa
- Journal Title
  
  Biotechnology Journal
  
  Volume: 9 Pages: 971-979
- DOI
  10.1002/biot.201300559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861161
[Journal Article] Rapid fabrication of engineered liver tissue using novel fibroblast system2014
- Author(s)
  1.Yusuke Sakai, Makiko Koike, Hideko Hasegawa, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Teruo Okano, and Susumu Eguchi
- Journal Title
  
  ALTEX Proceedings
  
  Volume: 3 Pages: 44-44
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461916
[Journal Article] Rapid fabricating technique for multi-layered human hepatic cell sheets by forceful contraction of the fibroblast monolayer.2014
- Author(s)
  Yusuke Sakai, Makiko Koike, Hideko Hasegawa, Kosho Yamanouchi, Akihiko Soyama, Mitsuhisa Takatsuki, Tamotsu Kuroki, Kazuo Ohashi, Teruo Okano, and Susumu Eguchi
- Journal Title
  
  PLos One
  
  Volume: 8 (7)
- DOI
  10.1371/journal.pone.0070970
- NAID
  120006986139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591868, KAKENHI-PROJECT-24300174, KAKENHI-PROJECT-25861161
[Journal Article] Rapid fabrication of engineered liver tissue using novel fibroblast system2014
- Author(s)
  1.Yusuke Sakai, Makiko Koike, Hideko Hasegawa, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Teruo Okano, and Susumu Eguchi
- Journal Title
  
  ALTEX Proceedings
  
  Volume: 3 Pages: 44-44
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861161
[Journal Article] Construction of liver tissue in vivo with preparative partial hepatic irradiation and growth stimulus: investigations of less invasive techniques and progenitor cells.2013
- Author(s)
  Kensuke Miyazaki, Kosho Yamanouchi, Yusuke Sakai, Izumi Yamaguchi, Mitsuhisa Takatsuki, Tamotsu Kuroki, Chandan Guha, and Susumu Eguchi
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 185 (2) Pages: 889-895
- DOI
  10.1016/j.jss.2013.06.016
- NAID
  120006986772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591868, KAKENHI-PROJECT-25462097, KAKENHI-PROJECT-25861161
[Patent] シート状物貼付デバイス2019
- Inventor(s)
  堺裕輔、江口晋、丸屋安広、大橋文哉、鮫島正
- Industrial Property Rights Holder
  堺裕輔、江口晋、丸屋安広、大橋文哉、鮫島正
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-19H04445
[Patent] 肝前駆細胞を含む細胞集団を製造する方法2019
- Inventor(s)
  堺裕輔、江口晋
- Industrial Property Rights Holder
  堺裕輔、江口晋
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H05908
[Patent] 肝前駆細胞を含む細胞集団を製造する方法2019
- Inventor(s)
  堺裕輔、江口晋
- Industrial Property Rights Holder
  堺裕輔、江口晋
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K19932
[Patent] 培養組織及びその製造方法2019
- Inventor(s)
  堺裕輔、江口晋、足立智彦、黄宇
- Industrial Property Rights Holder
  堺裕輔、江口晋、足立智彦、黄宇
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H05908
[Patent] 培養組織及びその製造方法2019
- Inventor(s)
  堺裕輔、江口晋、足立智彦、黄宇
- Industrial Property Rights Holder
  堺裕輔、江口晋、足立智彦、黄宇
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K19932
[Patent] シート状物貼付デバイス2018
- Inventor(s)
  堺裕輔、江口晋、丸屋安広、大橋文哉、鮫島正
- Industrial Property Rights Holder
  堺裕輔、江口晋、丸屋安広、大橋文哉、鮫島正
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K19932
[Patent] シート状物貼付デバイス2018
- Inventor(s)
  堺裕輔、江口晋、丸屋安広、大橋文哉、鮫島正
- Industrial Property Rights Holder
  堺裕輔、江口晋、丸屋安広、大橋文哉、鮫島正
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 肝臓表面における肝組織構築に向けた基材開発2022
- Author(s)
  白木川奈菜, 堺裕輔, 福村将成, 井嶋博之
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K19915
[Presentation] 胆管様組織と肝細胞スフェロイドの共培養による生体外での胆汁排泄機構の再構築2021
- Author(s)
  森翔一郎、堺裕輔、井嶋博之
- Organizer
  第43回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] リプログラミング技術を用いた肝内胆管の作製と胆汁排泄評価2021
- Author(s)
  森翔一郎、堺裕輔、井嶋博之
- Organizer
  第58回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] The successful induction of human liver progenitor cells by low-molecular compounds from mature hepatocytes in a severely cirrhotic liver undergoing liver transplantation2021
- Author(s)
  Miyoshi T, Hidaka M, Miyamoto D, Murakami S, Huang Y, Sakai Y, Kugiyama T, Hara T, Torashima Y, Ochiya T, Eguchi S
- Organizer
  第23回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] Chemical conversion of aged hepatocytes into bipotent liver progenitor cell2021
- Author(s)
  黄宇、宮本大輔、堺裕輔、原貴信、曽山明彦、日高匡章、村上俊介、松隈国仁、足立智彦、伊藤信一郎、金高賢悟、江口晋
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] Successful bile drainage through bile duct derived from chemically induced liver progenitors2020
- Author(s)
  黄宇、堺裕輔、原貴信、勝田毅、落谷孝広、足立智彦、宮本大輔、古維立、金高賢悟、江口晋
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] 胆道排出路を持った肝組織構築の試み2020
- Author(s)
  江口晋、宮本大輔、黄宇、原貴信、足立智彦、金高賢悟、堺裕輔、落谷孝広
- Organizer
  第19回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] 肝硬変組織から肝前駆細胞作製は可能か？2020
- Author(s)
  三好敬之、日高匡章、宮本大輔、堺裕輔、足立智彦、虎島泰洋、伊藤信一郎、金高賢悟、落谷孝広、江口晋
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] 管腔構造を有するヒト肝細胞／内皮細胞索状組織作製技術の確立2019
- Author(s)
  堺裕輔、中澤浩二、日高匡章、高槻光寿、江口晋
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 肝臓再構築に向けた研究と展望2019
- Author(s)
  堺裕輔、井嶋博之、落谷孝広、江口晋
- Organizer
  日本再生医療学会第1回秋季科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] Spontaneous formation of three－dimensional cell cysts from chemically-induced liver progenitors2019
- Author(s)
  Yu Huang, Yusuke Sakai, Takanobu Hara, Takeshi Katsuda, Takahiro Ochiya, Susumu Eguchi
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] 肝臓再構築に向けた研究と展望2019
- Author(s)
  堺裕輔、井嶋博之、落谷孝広、江口晋
- Organizer
  日本再生医療学会第1回秋季科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] ヒト肝分離における患者背景の検討2019
- Author(s)
  三好敬之、堺裕輔、濵田隆史、前川恭一郎、夏田孔史、大野慎一郎、足立智彦、日髙匡章、高槻光寿、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] 抗原性を消失させた肝細胞／肝癌細胞シート作製の試み2019
- Author(s)
  岡田怜美、高槻光寿、堺裕輔、日髙匡章、足立智彦、大野慎一郎、夏田孔史、濵田隆志、前川恭一郎、池田裕明、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] 胆汁うっ滞肝モデルにおける肝切除後の肝内リンパ管新生の影響2019
- Author(s)
  濵田隆史、日髙匡章、堺裕輔、夏田孔史、足立智彦、大野慎一郎、前川恭一郎、三好敬之、黄宇、飛永修一、田渕聡、高槻光寿、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 血管誘導を伴う皮下性ヒト肝組織構築での遺伝子発現解析2019
- Author(s)
  堺裕輔、高槻光寿、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] 血管誘導を伴う皮下性ヒト肝組織構築2019
- Author(s)
  堺裕輔、日髙匡章、高槻光寿、江口晋
- Organizer
  第38回長崎障害者支援再生医療研究会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 管腔構造を有するヒト肝細胞／内皮細胞索状組織作製技術の確立2019
- Author(s)
  堺裕輔、中澤浩二、日髙匡章、高槻光寿、井嶋博之、江口晋
- Organizer
  第1回細胞シート工学イノベーションフォーラム
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] Spontaneous formation of three－dimensional cell cysts from chemically-induced liver progenitors2019
- Author(s)
  Yu Huang, Yusuke Sakai, Takanobu Hara, Takeshi Katsuda, Takahiro Ochiya, Susumu Eguchi
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 管腔構造を有するヒト肝細胞／内皮細胞索状組織作製技術の確立2019
- Author(s)
  堺裕輔、中澤浩二、日高匡章、高槻光寿、江口晋
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] 血管誘導を伴う皮下性ヒト肝組織構築2019
- Author(s)
  堺裕輔、日髙匡章、高槻光寿、江口晋
- Organizer
  第38回長崎障害者支援再生医療研究会
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] 胆汁うっ滞肝モデルにおける肝切除後の肝内リンパ管新生の影響2019
- Author(s)
  濵田隆史、日髙匡章、堺裕輔、夏田孔史、足立智彦、大野慎一郎、前川恭一郎、三好敬之、黄宇、飛永修一、田渕聡、高槻光寿、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] ヒト肝分離における患者背景の検討2019
- Author(s)
  三好敬之、堺裕輔、濵田隆史、前川恭一郎、夏田孔史、大野慎一郎、足立智彦、日髙匡章、高槻光寿、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 管腔構造を有するヒト肝細胞／内皮細胞索状組織作製2019
- Author(s)
  堺裕輔、中澤浩二、江口晋、井嶋博之
- Organizer
  第55回九大生体材料・力学研究会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] 抗原性を消失させた肝細胞／肝癌細胞シート作製の試み2019
- Author(s)
  岡田怜美、高槻光寿、堺裕輔、日髙匡章、足立智彦、大野慎一郎、夏田孔史、濵田隆志、前川恭一郎、池田裕明、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 血管誘導を伴う皮下性ヒト肝組織構築での遺伝子発現解析2019
- Author(s)
  堺裕輔、高槻光寿、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 血管誘導を伴う皮下性ヒト肝組織構築での遺伝子発現解析2019
- Author(s)
  堺裕輔、高槻光寿、江口晋
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19H04445
[Presentation] Rapid fabrication of engineered human primary hepatocyte/fibroblast sheets for prevention of postoperative hepatic insufficiency2018
- Author(s)
  Yu Huang, Yusuke Sakai, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Susumu Eguchi
- Organizer
  5th TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] Time-dependent liver-specific gene expressions of vascularized subcutaneous human liver tissue2018
- Author(s)
  Yusuke Sakai, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Susumu Eguchi
- Organizer
  5th TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] Rapid fabrication of engineered human primary hepatocyte/fibroblast sheets for prevention of postoperative hepatic insufficiency2018
- Author(s)
  Yu Huang, Yusuke Sakai, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Susumu Eguchi
- Organizer
  5th TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] Unique cell morphologies and liver-specific gene expressions of chemically-induced liver progenitors2018
- Author(s)
  Yu Huang、Yusuke Sakai、Takanobu Hara、Takeshi Katsuda、Takahiro Ochiya、Susumu Eguchi
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 効率的・移植可能な肝胆膵領域での再生医療2018
- Author(s)
  江口晋、黄宇、堺裕輔
- Organizer
  第17回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 効率的・移植可能な肝胆膵領域での再生医療2018
- Author(s)
  江口晋、黄宇、堺裕輔
- Organizer
  第17回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] Time-dependent liver-specific gene expressions of vascularized subcutaneous human liver tissue2018
- Author(s)
  usuke Sakai, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Susumu Eguchi
- Organizer
  5th TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19932
[Presentation] 細胞シート工学を利用した血管網を有する皮下培養型ヒト肝組織作製2017
- Author(s)
  堺裕輔、高槻光寿、江口晋
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 術後急性肝不全予防のための迅速な肝細胞複合シート作製2017
- Author(s)
  堺裕輔、小池真章子、曽山明彦、日高匡章、高槻光寿、江口晋
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 細胞シート工学を利用した血管網を有する皮下培養型ヒト肝組織作製2017
- Author(s)
  堺裕輔、高槻光寿、江口晋
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 術後急性肝不全予防のための迅速な肝細胞複合シート作製2017
- Author(s)
  堺裕輔、小池真章子、曽山明彦、日高匡章、高槻光寿、江口晋
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 孔貫通型シリコーンフィルムを利用した肝類似パターニング2017
- Author(s)
  久賀千尋、堺裕輔、中澤浩二、江口晋
- Organizer
  第54回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 皮下性ヒト肝組織構築に伴う血管網と肝特異機能発現の評価2016
- Author(s)
  堺裕輔、小池真章子、山之内孝彰、曽山明彦、日高匡章、黒木保、江口晋
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 肝特異的な特徴を有するヒト肝組織の皮下構築と機能発現解析2016
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、曽山明彦、日高匡章、高槻光寿、江口晋
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター（大阪府、大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 安定した肝細胞複合シート作製のための線維芽細胞培養条件の検討2016
- Author(s)
  小池真章子、堺裕輔、川原大輔、高槻光寿、江口晋
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター（大阪府、大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16H05908
[Presentation] 肝特異的な特徴を有するヒト肝組織の皮下構築と機能発現解析2016
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、曽山明彦、日高匡章、高槻光寿、江口晋
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター（大阪府、大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 皮下性ヒト肝細胞/線維芽細胞シートによる肝再生医療2016
- Author(s)
  日高匡章, 堺裕輔, 曽山明彦, 小池真章子, 山之内孝彰, 夏田孔史, 大野慎一郎, 藤田文彦, 黒木保, 江口晋
- Organizer
  第24回 JDDW
- Place of Presentation
  兵庫県神戸市神戸コンベンションセンター
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K01295
[Presentation] 安定した肝細胞複合シート作製のための線維芽細胞培養条件の検討2016
- Author(s)
  小池真章子、堺裕輔、川原大輔、高槻光寿、江口晋
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター（大阪府、大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 放射線性肝障害と肝切除を組み合わせたラットモデルに対する多層肝細胞シートの移植効果2016
- Author(s)
  Zhassulan Baimakhanov / 長崎大学　移植・消化器外科共著者：山之内孝彰、堺裕輔、曽山明彦、日高匡章、高槻光寿、藤田文彦、金高賢悟、黒木保、江口晋
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25462097
[Presentation] Zhassulan Baimakhanov, Kosho Yamanouchi, Yusuke Sakai, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Fumihiko Fujita, Kengo Kanetaka, Kazuma Kobayashi, Tamotsu Kuroki, Susumu Eguchi2015
- Author(s)
  Baimakhanov Z, Yamanouchi K, Sakai Y, Koike M, Soyama A, Hidaka M, Takatsuki M, Fujita F, Kanetaka K, Kuroki T, Eguchi S.
- Organizer
  American College of Surgeon, Clinical Congress 2015
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462097
[Presentation] Efficacy of multi-layered hepatocyte sheet transplantation for radiation-induced liver damage and partial hepatectomy in a rat model2015
- Author(s)
  Zhassulan Baimakhanov, Kosho Yamanouchi, Yusuke Sakai, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Fumihiko Fujita, Kengo Kanetaka, Tamotsu Kuroki, Susumu Eguchi
- Organizer
  Clinical Congress 2015, American College of Surgeons
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] Reconstruction of vascularized subcutaneous liver tissue for minimally invasive cell therapy2015
- Author(s)
  Yusuke Sakai, Makiko Koike, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Susumu Eguchi
- Organizer
  ASGCT 18th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2015-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 支持細胞密度による初代肝細胞の形態および機能発現制御2015
- Author(s)
  小池真章子、堺裕輔、川原大輔、黒木保、江口晋
- Organizer
  第22回肝細胞研究会
- Place of Presentation
  米子コンベンションセンター（鳥取）
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 皮下性ヒト肝組織構築による肝疾患治療2015
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、曽山明彦、日高匡章、黒木保、江口晋
- Organizer
  第22回肝細胞研究会
- Place of Presentation
  米子コンベンションセンター（鳥取）
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 細胞シート工学を利用した血管誘導ヒト肝組織の迅速な自己構築2015
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、曽山明彦、日高匡章、高槻光寿、黒木保、江口晋
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-04-16
- Invited
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] Reversibly-assembled microfluidic device consists of microwells and microchannels for stable perfusion culture of spheroid array2012
- Author(s)
  Yusuke Sakai, Koji Hattori, Shinji Sugiura, Toshiyuki Kanamori, and Kohji Nakazawa
- Organizer
  2012 IEEE EMBS Micro and Nanotechnology in Medicine Conference, Hawaii, USA
- Place of Presentation
  アメリカ
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] ヒト初代肝細胞/線維芽細胞複合シートが創造する第二の肝臓
- Author(s)
  堺裕輔、高槻光寿、江口晋
- Organizer
  JDDW2013
- Place of Presentation
  東京（グランドプリンスホテル新高輪）
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] 肝細胞／各種支持細胞共培養シートの構造と機能発現の評価
- Author(s)
  小池真章子、堺裕輔、黒木保、江口晋
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] Reconstruction of Vascularized Subcutaneous Liver Tissue for Minimally Invasive Cell Therapy
- Author(s)
  Yusuke Sakai, Makiko Koike, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, and Susumu Eguchi
- Organizer
  ASGCT 18th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2015-05-13 – 2015-05-16
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] 肝移植の代替または再生補助療法としてのヒト肝細胞シートを用いた再生医療デバイスの開発
- Author(s)
  高槻光寿、堺裕輔、江口晋
- Organizer
  第40回日本肝臓学会西部会
- Place of Presentation
  岐阜（長良川国際会議場）
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] 共培養型肝細胞シートにおける支持細胞の効果
- Author(s)
  小池真章子、堺裕輔、高槻光寿、曽山明彦、虎島泰洋、藤田文彦、金高賢悟、黒木保、江口晋
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] Reconstruction of Vascularized Subcutaneous Liver Tissue for Minimally Invasive Cell Therapy
- Author(s)
  Yusuke Sakai, Makiko Koike, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, and Susumu Eguchi
- Organizer
  ASGCT 18th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2015-05-13 – 2015-05-16
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 共培養技術に基づく重層化肝細胞シートの開発
- Author(s)
  堺裕輔、高槻光寿、山之内孝彰、曽山明彦、村岡いづみ、田中貴之、山口泉、木下綾華、原貴信、鵜頭理恵、大橋一夫、岡野光夫、黒木保、江口晋
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] ヒト初代肝細胞/線維芽細胞複合シートが創造する第二の肝臓
- Author(s)
  堺裕輔、高槻光寿、江口晋
- Organizer
  JDDW2013
- Place of Presentation
  東京（グランドプリンスホテル新高輪）
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] 異所性肝組織構築のための再生医療デバイスの創成
- Author(s)
  堺裕輔、小池真章子、山之内孝彰、曽山明彦、高槻光寿、黒木保、鵜頭理恵、大橋一夫、岡野光夫、江口晋
- Organizer
  第68回日本消化器外科学会総会
- Place of Presentation
  宮崎（シーガイアコンベンションセンター）
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] Rapid fabrication of engineered liver tissue using novel fibroblast system
- Author(s)
  Yusuke Sakai, Makiko Koike, Hideko Hasegawa, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Teruo Okano, and Susumu Eguchi
- Organizer
  9th World Congress on Alternatives and Animal Use in the Life Sciences (WC9)
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] 細胞シート工学を利用した血管誘導ヒト肝組織の迅速な自己構築
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、曽山明彦、日高匡章、高槻光寿、黒木保、江口晋
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-04-16 – 2015-04-18
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] ヒト肝細胞シートによる肝再生を目指して～ヒト肝細胞シート作製技術の確立～
- Author(s)
  堺裕輔、高槻光寿、山之内孝彰、曽山明彦、村岡いづみ、大橋一夫、江口晋
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  石川
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] Development of a multilayered fibroblast/hepatocyte sheet for regenerative medicine
- Author(s)
  Yusuke Sakai, Mitsuhisa Takatsuki, Kosho Yamanouchi, Akihiko Soyama, Izumi Muraoka, Rie Utoh, Kazuo Ohashi, Teruo Okano, Tamotsu Kuroki, and Susumu Eguchi
- Organizer
  3rd TERMIS World Congress in Vienna
- Place of Presentation
  オーストリア
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] 異所性肝組織構築のための再生医療デバイスの創成
- Author(s)
  堺裕輔、小池真章子、山之内孝彰、曽山明彦、高槻光寿、黒木保、鵜頭理恵、大橋一夫、岡野光夫、江口晋
- Organizer
  第68回日本消化器外科学会総会
- Place of Presentation
  宮崎（シーガイアコンベンションセンター）
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] ヒト初代肝細胞/線維芽細胞複合シートによる異所性肝組織構築
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、曽山明彦、高槻光寿、黒木保、鵜頭理恵、大橋一夫、岡野光夫、江口晋
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] ヒト初代肝細胞複合シート移植における支持細胞の種類の効果
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、日高匡章、曽山明彦、高槻光寿、黒木保、岡野光夫、江口晋
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] Rapid fabrication of engineered liver tissue using novel fibroblast system
- Author(s)
  Yusuke Sakai, Makiko Koike, Hideko Hasegawa, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Teruo Okano, and Susumu Eguchi
- Organizer
  9th World Congress on Alternatives and Animal Use in the Life Sciences (WC9)
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] ヒト初代肝細胞複合シート移植における支持細胞の種類の効果
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、日高匡章、曽山明彦、高槻光寿、黒木保、岡野光夫、江口晋
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] 肝細胞／各種支持細胞共培養シートの構造と機能発現の評価
- Author(s)
  小池真章子、堺裕輔、黒木保、江口晋
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] 再生医療のための肝細胞組織工学
- Author(s)
  堺裕輔、小池真章子、山之内孝彰、曽山明彦、高槻光寿、黒木保、江口晋
- Organizer
  第27回長崎DDS・再生医療研究会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] Reconstruction of Vascularized Subcutaneous Liver Tissue for Minimally Invasive Cell Therapy
- Author(s)
  Yusuke Sakai, Makiko Koike, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, and Susumu Eguchi
- Organizer
  ASGCT 18th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2014-05-13 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] 細胞シート工学を利用した血管誘導ヒト肝組織の迅速な自己構築
- Author(s)
  堺裕輔、小池真章子、長谷川英子、山之内孝彰、曽山明彦、日高匡章、高槻光寿、黒木保、江口晋
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-04-16 – 2015-04-18
- Data Source
  KAKENHI-PROJECT-23591868
[Presentation] 肝移植の代替または再生補助療法としてのヒト肝細胞シートを用いた再生医療デバイスの開発
- Author(s)
  高槻光寿、堺裕輔、江口晋
- Organizer
  第40回日本肝臓学会西部会
- Place of Presentation
  岐阜（長良川国際会議場）
- Data Source
  KAKENHI-PROJECT-25861161
[Presentation] Rapid fabrication of engineered liver tissue using novel fibroblast system
- Author(s)
  Yusuke Sakai, Makiko Koike, Hideko Hasegawa, Kosho Yamanouchi, Akihiko Soyama, Masaaki Hidaka, Mitsuhisa Takatsuki, Tamotsu Kuroki, Teruo Okano, and Susumu Eguchi
- Organizer
  9th World Congress on Alternatives and Animal Use in the Life Sciences (WC9)
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PROJECT-26461916
[Presentation] 線維芽細胞/肝細胞重層化シートの開発およびin vivo肝特異機能発現
- Author(s)
  堺裕輔、高槻光寿、山之内孝彰、曽山明彦、鵜頭理恵、大橋一夫、岡野光夫、黒木保、江口晋
- Organizer
  第19回肝細胞研究会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-23591868

1. EGUCHI Susumu (80404218)

# of Collaborated Projects: 8 results

# of Collaborated Products: 89 results
2. YAMANOUCHI Kosho (10448508)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
3. SOYAMA Akihiko (10549447)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
4. 中澤浩二 (00304733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. KOIKE Makiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
6. TAKATSUKI Mitsuhisa

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
7. HIDAKA Masaaki

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
8. KANEMATSU Takashi (40128004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 金高賢悟 (10549570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 丸屋安広 (20817085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. HASEGAWA Hideko

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. OHASHI Kazuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. NAKAO Kazuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. AKAZAWA Yuuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 日高匡章

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
16. 中島正洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 李桃生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 浜田隆志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 紙谷聡英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAI Yusuke 堺 裕輔

Research Projects

Research Products

Co-Researchers

Fabrication of detachable-liver based on liver-derived ECM sponge needlePrincipal Investigator

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Fabrication of bioengineered sphincter construct with myoblast sheet

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Reconstruction of liver from arranged-hepatocytes/liver sinusoidal endothelial cells/cholangiocytes tissuesPrincipal Investigator

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In vitro reconstruction of functional bile canaliculus-intrahepatic bile duct structurePrincipal Investigator

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Fabrication of human liver with mimicking hepatic lobule structures by alternately-arranged human hepatocyte/endotherial cell tissue transplantationPrincipal Investigator

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Prevention of postoperative biliary stricture by application of hybrid bioartificial bile duct

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Acute liver failure treatment using rapid fabricated engineered hepatocyte sheets

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Construction of liver tissue in vivo with preparative partial hepatic irradiation and growth stimulus: investigations of less invasive techniques and progenitor cells.

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Construction of vascularized ectopic liver tissue from engineered human hepatocyte sheetPrincipal Investigator

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Reconstruction of human liver sheet for preclinical study of liver regenerative medicine

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[Book] 再生医療用語ハンドブック： 肝細胞移植2015

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[Journal Article] Successful induction of human chemically induced liver progenitors with small molecules from damaged liver2022

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[Journal Article] Bioengineering of a CLiP‐derived tubular biliary‐duct‐like structure for bile transport in vitro2021

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[Journal Article] Functional changes of cocultured hepatocyte sheets subjected to continuous liver regeneration stimulation in cDNA-uPA/SCID mouse: Differences in transplantation sites2021

SAKAI Yusuke 堺裕輔

[Book] 再生医療用語ハンドブック：　肝細胞移植2015