TAKAHASHI KUNIHIKO 高橋邦彦

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TAKAHASHI Kunihiko 高橋邦彦

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Researcher Number	10610230
Affiliation (Current)	2022: 大阪大学, 大学院医学系研究科, 招へい教員
Affiliation (based on the past Project Information) *help	2016 – 2017: 大阪大学, 医学系研究科, 招へい教員 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2015: 大阪大学, 医学(系)研究科(研究院), 招へい教員 2014: 大阪大学, 医学系研究科, 助教 2013: 大阪大学, 医学部附属病院, 助教 2011 – 2013: 大阪大学, 医学(系)研究科(研究院), 特任助教(常勤)
Review Section/Research Field	Except Principal Investigator Pediatrics
Keywords	Except Principal Investigator 肺高血圧症 / CNP / ナトリウム利尿ペプチド受容体 / cGMP / PAH / NPR-B / cyclic GMP / 心不全 / 小児循環器学 / 遺伝子治療

Multiple development of treatment for pulmonary arterial hypertension by constitutive active natriuretic peptide receptor
- Principal Investigator
  
  Kogaki Shigetoyo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Overexpression of constitutively active NPR-B inhibits cardiac hypertrophy
- Principal Investigator
  
  OKADA YOKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Type B Human Natriuretic Peptide Receptor with a novel gain-of-function mutation provides therapeutic potential in the treatment of pulmonary arterial hypertension.
- Principal Investigator
  
  KOGAKI Shigetoyo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University

All 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Constitutively active form of natriuretic peptide receptor 2 ameliorates experimental pulmonary arterial hypertension.2016
- Author(s)
  Nawa N, Ishida H, Katsuragi S, Baden H, Takahashi K, Higeno R, Torigoe F, Mihara S, Narita J, Miura K, Nakamura K, Kogaki S, Ozono K.
- Journal Title
  
  Mol Ther Methods Clin Dev
  
  Volume: 3 Pages: 16044-16044
- DOI
  10.1038/mtm.2016.44
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09690, KAKENHI-PROJECT-16K10065
[Presentation] B型ナトリウム利尿ペプチド受容体（NPR-B）機能獲得変異体による心不全予防効果の検討2016
- Author(s)
  馬殿洋樹，桂木慎一，那波伸敏，石田秀和，成田淳，高橋邦彦，小垣滋豊，大薗恵一
- Organizer
  第52回日本小児循環器学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-06
- Data Source
  KAKENHI-PROJECT-15K09690
[Presentation] Intravascular injection of Sendai virus vector carrying continuously cGMP producing mutant of type B Natriuretic Peptide Receptor can ameliorate pulmonary arterial hypertension.2015
- Author(s)
  Nawa N, Ishida H, Katsuragi S, Baden H, Takahashi K, Kogaki S, Higeno R, Torigoe F, Mihara S, Narita J, Miura K, Ozono K
- Organizer
  American Heart Association (AHA) Scientific Sessions 2015
- Place of Presentation
  Orlando, Florida, United States
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09690
[Presentation] センダイウイルスベクターを用いた肺動脈性肺高血圧症(PAH)に対する新たな遺伝子治療の可能性2015
- Author(s)
  那波　伸敏、石田　秀和、馬殿　洋樹、高橋　邦彦、小垣　滋豊、廣瀬将樹、桂木慎一、髭野　亮太、三原聖子、成田淳、三浦　弘司、大薗　恵一
- Organizer
  第51回日本小児循環器学会総会・学術集会
- Place of Presentation
  ホテル日航東京
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K09690
[Presentation] CNP受容体恒常活性型変異体を用いた肺高血圧症の新たな治療法2015
- Author(s)
  那波　伸敏、石田　秀和、馬殿　洋樹、桂木慎一、高橋　邦彦、小垣　滋豊、廣瀬将樹、鳥越　史子、髭野　亮太、三原聖子、成田淳、三浦　弘司、大薗　恵一
- Organizer
  第4回日本肺循環学会・第3回日本肺高血圧学会　合同学術集会
- Place of Presentation
  ステーションコンファレンス東京
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-15K09690
[Presentation] Therapeutic application of constitutively active type B natriuretic peptide receptor for pulmonary arterial hypertension2015
- Author(s)
  Nawa N, Ishida H, Baden H, Takahashi K, Higeno R, Mihara S, Ishii R, Ichimori H, Yabushita-Okada Y, Miura K, Kogaki S, Ozono K
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-15K09690
[Presentation] Therapeutic Application of Type B Natriuretic Peptide Receptor With a Novel Gain-of-function Mutation in the Treatment of Pulmonaly Arterial Hypertension2013
- Author(s)
  Nawa N, Ishida H, Baden H, Takahashi K, Kogaki S, Yabushita-Okada Y, Ichimori H, Ishii R, Mihara S, Higeno R, Miura K, Ozono K.
- Organizer
  American Heart Association, Scientiic Sessions 2013
- Place of Presentation
  米国Dallas
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] Therapeutic application of type B natriuretic peptide receptor with a novel gain-of-function mutation in the treatment of pulmonary arterial hypertension2013
- Author(s)
  Nawa N, Ishida H, Baden H, Takahashi K, Kogaki S, Yabushita-Okada Y, Ichimori H, Ishii R, Mihara S, Higeno R, Miura K, Ozono K
- Organizer
  American Heart Association, Scientiic Sessions 2013
- Place of Presentation
  Dallas, Texas（アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] 機能獲得変異型N-PRBによる心不全治療戦略2013
- Author(s)
  馬殿洋樹, 髭野亮太, 那波伸敏, 石井良, 市森裕章, 内川俊毅, 高橋邦彦, 岡田陽子, 小垣滋豊, 大薗恵一
- Organizer
  第49回日本小児循環器学会総会
- Place of Presentation
  国立オリンピック記念青少年総合センター
- Data Source
  KAKENHI-PROJECT-25461620
[Presentation] Constitutively Active NPR-B (Type-B Human Natriuretic Peptide Receptor) Inhibits Cardiomyocyte Hypertrophy and Cardiac Fibroblast Fibrosis2013
- Author(s)
  Baden H, Nawa N, Ishida H, Takahashi K, Kogaki S, Yabushita-Okada Y, Ichimori H, Ishii R, Mihara S, Higeno R, Miura K, Ozono K.
- Organizer
  AHA2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-25461620
[Presentation] C-type natriuretic peptide (CNP)受容体(NPR-B)の機能獲得型変異体を用いた、肺動脈性高血圧症(PAH)に対する新たな治療アプローチ2013
- Author(s)
  那波伸敏,石田秀和,馬殿洋樹,高橋邦彦,小垣滋豊,市森裕章,内川俊毅,石井良,髭野亮太,岡田陽子,三浦弘司,大薗恵一
- Organizer
  第19回日本小児肺循環研究会
- Place of Presentation
  東京
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] C-type natriuretic peptide(CNP)受容体(NPR-B)の機能獲得型変異体を用いた、肺高血圧症に対する新たな治療アプローチ(第3報)2013
- Author(s)
  那波伸敏,石田秀和,馬殿洋樹,高橋邦彦,小垣滋豊,市森裕章,石井良,髭野亮太,藪下陽子,三浦弘司,大薗恵一
- Organizer
  第49回日本小児循環器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] C-type natriuretic peptide(CNP)受容体(NPR-B)の機能獲得型変異体を用いた、肺動脈性肺高血圧症に対する新たな治療アプローチ(第2報)2012
- Author(s)
  那波伸敏,石田秀和,高橋邦彦,小垣滋豊,市森裕章,内川俊毅,藪下陽子,三原聖子,馬殿洋樹,三浦弘司,大薗恵一
- Organizer
  第48回日本小児循環器学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] C-type natriuretic peptide (CNP)受容体(NPR-B)の機能獲得型変異体を用いた,肺動脈高血圧症(PAH)に対する新たな治療アプローチ2012
- Author(s)
  那波伸敏,石田秀和,高橋邦彦,小垣滋豊,市森裕章,内川俊毅,成田淳,岡田陽子,三浦弘司,大薗恵一
- Organizer
  第18回日本小児肺循環研究会
- Place of Presentation
  東京
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] C-type natriuretic peptide (CNP) 受容体(NPR-B)の機能獲得型変異体を用いた、肺動脈性肺高血圧症に対する新たな治療アプローチ第2報2012
- Author(s)
  那波　伸敏、石田　秀和、高橋　邦彦、小垣　滋豊、市森　裕章、内川　俊毅、藪下　陽子、三原聖子、馬殿洋樹、三浦　弘司、大薗　恵一
- Organizer
  第48回日本小児循環器学会総会・学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] C-type natriuretic peptid (CNP) 受容体　(NPR-B)の昨日獲得型変異体を用いた，肺動脈性肺高血圧症(PAH)に対する新たな治療アプローチ2012
- Author(s)
  那波伸敏，石田秀和，高橋邦彦，小垣滋豊，市森裕章，内川俊毅，成田淳，前川周，岡田陽子，三浦弘司，大薗恵一
- Organizer
  第18回日本小児肺循環研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] C-type natriuretic peptide (CNP) 受容体(NPR-B)の機能獲得型変異体を用いた、肺動脈性肺高血圧症(PAH)に対する新たな治療アプローチ
- Author(s)
  那波　伸敏、石田　秀和、馬殿　洋樹、高橋　邦彦、小垣　滋豊、市森　裕章、内川　俊毅、石井　良、髭野　亮太、岡田　陽子、三浦　弘司、大薗　恵一
- Organizer
  第19回日本小児肺循環研究会
- Place of Presentation
  笹川記念館
- Data Source
  KAKENHI-PROJECT-23591567
[Presentation] B型ナトリウム利尿ペプチド受容体(NPR-B)の機能獲得型変異体による心不全治療戦略
- Author(s)
  馬殿洋樹, 那波伸敏, 島越史子, 三原聖子, 石井良, 市森裕章, 高橋邦彦, 岡田陽子, 小垣滋豊, 大薗恵一
- Organizer
  第50回日本小児循環器学会学術集会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-07-03 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-25461620

1. KOGAKI Shigetoyo (00311754)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
2. NAWA Nobutoshi (30617543)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ICHIMORI Hiroaki (60467553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. ISHIDA Hidekazu (50467552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. OKADA YOKO (30457022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 馬殿洋樹 (60644614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. KATSURAGI SHINICHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 那波伸俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results
9. 成田淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI KUNIHIKO 高橋 邦彦

TAKAHASHI Kunihiko 高橋 邦彦

Research Projects

Research Products

Co-Researchers

Multiple development of treatment for pulmonary arterial hypertension by constitutive active natriuretic peptide receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Overexpression of constitutively active NPR-B inhibits cardiac hypertrophy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Type B Human Natriuretic Peptide Receptor with a novel gain-of-function mutation provides therapeutic potential in the treatment of pulmonary arterial hypertension.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Constitutively active form of natriuretic peptide receptor 2 ameliorates experimental pulmonary arterial hypertension.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] B型ナトリウム利尿ペプチド受容体（NPR-B）機能獲得変異体による心不全予防効果の検討2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Intravascular injection of Sendai virus vector carrying continuously cGMP producing mutant of type B Natriuretic Peptide Receptor can ameliorate pulmonary arterial hypertension.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] センダイウイルスベクターを用いた 肺動脈性肺高血圧症(PAH)に対する新たな遺伝子治療の可能性2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] CNP受容体恒常活性型変異体を用いた肺高血圧症の新たな治療法2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Therapeutic application of constitutively active type B natriuretic peptide receptor for pulmonary arterial hypertension2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Therapeutic Application of Type B Natriuretic Peptide Receptor With a Novel Gain-of-function Mutation in the Treatment of Pulmonaly Arterial Hypertension2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Therapeutic application of type B natriuretic peptide receptor with a novel gain-of-function mutation in the treatment of pulmonary arterial hypertension2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 機能獲得変異型N-PRBによる心不全治療戦略2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Constitutively Active NPR-B (Type-B Human Natriuretic Peptide Receptor) Inhibits Cardiomyocyte Hypertrophy and Cardiac Fibroblast Fibrosis2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] C-type natriuretic peptide (CNP)受容体(NPR-B)の機能獲得型変異体を用いた、肺動脈性高血圧症(PAH)に対する新たな治療アプローチ2013

Author(s)

TAKAHASHI KUNIHIKO 高橋邦彦

TAKAHASHI Kunihiko 高橋邦彦

[Presentation] センダイウイルスベクターを用いた肺動脈性肺高血圧症(PAH)に対する新たな遺伝子治療の可能性2015

[Presentation] C-type natriuretic peptide (CNP) 受容体(NPR-B)の機能獲得型変異体を用いた、肺動脈性肺高血圧症に対する新たな治療アプローチ第2報2012

[Presentation] C-type natriuretic peptid (CNP) 受容体　(NPR-B)の昨日獲得型変異体を用いた，肺動脈性肺高血圧症(PAH)に対する新たな治療アプローチ2012

[Presentation] C-type natriuretic peptide (CNP) 受容体(NPR-B)の機能獲得型変異体を用いた、肺動脈性肺高血圧症(PAH)に対する新たな治療アプローチ