Koshimizu Hisatsugu 小清水久嗣

… Alternative Names

小清水久嗣コシミズヒサツグ

KOSHIMIZU Hisatsugu 小清水久嗣

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Researcher Number	10610842
Other IDs	https://orcid.org/0000-0002-8619-6678
Affiliation (Current)	2024: 藤田医科大学, その他部局等, 教授
Affiliation (based on the past Project Information) *help	2022: 藤田医科大学, その他部局等, 教授 2017: 藤田保健衛生大学, 総合医科学研究所, 助教 2013 – 2015: 藤田保健衛生大学, 総合医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Neurochemistry/Neuropharmacology Except Principal Investigator Basic / Social brain science
Keywords	Principal Investigator 脳由来神経栄養因子 / BDNF / ドパミンニューロン / CRH / CRH-BP / CRH結合蛋白質 / 細胞成熟度異常 / 神経細胞成熟度変化 / 精神疾患 / モデルマウス … More / うつ病 / 統合失調症 / 歯状回 / 海馬 / 細胞成熟度 … More Except Principal Investigator 神経科学 / バイオテクノロジー / 遺伝学 / トランスレーショナルリサーチ / 細胞・組織 / 脳神経疾患 / 脳・神経 / 神経成熟度 / Shn2欠損マウス / 3D電顕コネクトーム / 網羅的行動解析 / バイオインフォマティクス / 非成熟歯状回 Less

中脳黒質におけるCRH結合蛋白質の機能解析Principal Investigator
- Principal Investigator
  
  小清水久嗣
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Fujita Health University
Analysis and regulation of bi-directional changes in maturation status of brain cells utilising in vitro hightrokghput assay systemPrincipal Investigator
- Principal Investigator
  
  KOSHIMIZU Hisatsugu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Fujita Health University
Elucidation and regulation of bi-directional changes in neuronal maturation status
- Principal Investigator
  
  Miyakawa Tsuyoshi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Fujita Health University

All 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 脳科学辞典「行動テストバッテリー」2013
- Author(s)
  高雄啓三, 小清水久嗣, 宮川剛
- Total Pages
  1
- Publisher
  脳科学辞典編集委員会
- Data Source
  KAKENHI-PROJECT-25430077
[Journal Article] Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism.2017
- Author(s)
  Murano T, Koshimizu H, Hagihara H, *Miyakawa T.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 44531-44531
- DOI
  10.1038/srep44531
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078, KAKENHI-PLANNED-16H06462
[Journal Article] Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice2014
- Author(s)
  Koshimizu H, Takao K, Matozaki T, Ohnishi H, Miyakawa T
- Journal Title
  
  PLoSOne
  
  Volume: 9 Issue: 2 Pages: e89584-e89584
- DOI
  10.1371/journal.pone.0089584
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PUBLICLY-24111508, KAKENHI-PUBLICLY-24111546, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25242078, KAKENHI-PROJECT-25350989, KAKENHI-PROJECT-25430077, KAKENHI-PUBLICLY-26111703, KAKENHI-PROJECT-26670110
[Journal Article] ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response.2013
- Author(s)
  Umemori J, Takao K, Koshimizu H, Hattori S, Furuse T, Wakana S, Miyakawa T.
- Journal Title
  
  BMC Res Notes
  
  Volume: 6(1) Issue: 1 Pages: 203-203
- DOI
  10.1186/1756-0500-6-203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24111546, KAKENHI-PUBLICLY-25116526, KAKENHI-PROJECT-25350989, KAKENHI-PROJECT-25430077
[Presentation] A genome-wide association study identifies a novel locus associated with depressive state in the Japanese population2017
- Author(s)
  Hisatsugu Koshimizu, Shinya Asano, Shoko Takahashi, Kenji Saito, and Tsuyoshi Miyakawa
- Organizer
  第47回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] A genome-wide association study identifies a novel locus associated with depressive state in the Japanese population2017
- Author(s)
  Koshimizu H., Asano S., Takahashi S., Saito K., Miyakawa T.
- Organizer
  The 25th World Congress of Psychiatric Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016
- Author(s)
  小清水久嗣, 萩原英雄, 宮川剛
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis2016
- Author(s)
  Koshimizu H., Hagihara H., Miyakawa T.
- Organizer
  15th Annual Molecular and Cellular Cognition Society Meeting
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016
- Author(s)
  Koshimizu H., Hagihara H., Miyakawa T.
- Organizer
  46th Annual meeting of Society for Neuroscience
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016
- Author(s)
  Koshimizu H., Hagihara H., Miyakawa T.
- Organizer
  (JSNP) 第46回日本神経精神薬理学会年会
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016
- Author(s)
  Koshimizu H., Hagihara H., Miyakawa T.
- Organizer
  30th CINP（The International College of Neuropsychopharmacology） World Congress of Neuropsychopharmacology
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Transcriptomic “hyper-maturity” of the hippocampus in mice2015
- Author(s)
  Koshimizu H., Hagihara H., Ohira K., Takao T., Miyakawa T.
- Organizer
  Society for Neuroscience 45th Annual Meeting
- Place of Presentation
  米国シカゴ
- Year and Date
  2015-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Transcriptomic “hyper-maturity” of the hippocampal dentate gyrus in mice2015
- Author(s)
  Hisatsugu Koshimizu, Hideo Hagihara, Koji Ohira, Keizo Takao, Tsuyoshi Miyakawa
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] マウス海馬歯状回における「過成熟」現象2015
- Author(s)
  Koshimizu H., Hagihara H., Ohira K., Keizo Takao K., Miyakawa T.
- Organizer
  第３８回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Transcriptomic “hyper-maturity” of the hippocampus in mice2015
- Author(s)
  Koshimizu H., Hagihara H., Ohira K., Takao T., Miyakawa T.
- Organizer
  15th Annual MCCS Symposium and Poster Session
- Place of Presentation
  米国シカゴ
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse lines with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014
- Author(s)
  Koshimizu H., Hagihara H., Takao T., Miyakawa T.
- Organizer
  Society for Neuroscience 44th Annual Meeting
- Place of Presentation
  Washington, DC
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Contrasting expression pattern for immaturity and maturity marker genes in the dentate gyrus between mouse lines with “immature dentate gyrus” and mice overexpressing glucocorticoid receptor2014
- Author(s)
  Hisatsugu Koshimizu, Hideo Hagihara, Keizo Takao, Tsuyoshi Miyakawa
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse lines with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014
- Author(s)
  Koshimizu H., Hagihara H., Takao T., Miyakawa T.
- Organizer
  Annual Molecular and Cellular Cognition Society Meeting
- Place of Presentation
  Washington, DC
- Year and Date
  2014-11-13
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse line with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014
- Author(s)
  Hisatsugu Koshimizu, Hideo Hagihara, Keizo Takao, Tsuyoshi Miyakawa
- Organizer
  Molecular and Cellular Cognition Society
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse lines with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014
- Author(s)
  Koshimizu H., Hagihara H., Takao T., Miyakawa T.
- Organizer
  日本神経科学学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Transcriptomic Effects of Antidepressant Treatment and Glucocorticoid Receptor-overexpression on the Maturational Status of Brain Cells in Mice2014
- Author(s)
  T Miyakawa, H Koshimizu, K Ohira, H Hagihara, R Takeuchi, K Takao
- Organizer
  American College of Neuropsychopharmacology 53rd Annual Meeting
- Place of Presentation
  Phoenix, AZ
- Year and Date
  2014-12-09
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Contrasting expression patterns for immaturity and maturity marker genes in the dentate gyrus between mouse line with ‘immature dentate gyrus’ and mice overexpressing glucocorticoid receptor2014
- Author(s)
  Hisatsugu Koshimizu, Hideo Hagihara, Keizo Takao, Tsuyoshi Miyakawa
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Contrasting expression paterns for immaturity and maturity marker genes in the dentate gyrus between mouse lines with ‘immature dentate gyrus’ and mice overexpressing glucocor8coid receptor2014
- Author(s)
  Koshimizu H., Ohira K., Hagihara H., Takao T., Miyakawa T.
- Organizer
  包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Dysregulation of BDNF-MAPK signaling pathway in the hippocampus of mice with “immature dentate gyrus”2013
- Author(s)
  Koshimizu H., Ohira K., Hagihara H., Takao K., Takagi T., Kataoka M., Ishii S., Takahashi M., Miyakawa T.
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Dysregulation of BDNF signaling pathway in the hippocampus of mice with “immature dentate gyrus”2013
- Author(s)
  Koshimizu H., Ohira K., Hagihara H., Takao K., Takagi T., Kataoka M., Ishii S., Takahashi M., Miyakawa T.
- Organizer
  Annual Molecular and Cellular Cognition Society Meeting
- Place of Presentation
  米国 San Diego
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Dysregulation of BDNF signaling pathway in the hippocampus of mice with “immature dentate gyrus”2013
- Author(s)
  Koshimizu H., Ohira K., Hagihara H., Takao K., Takagi T., Kataoka M., Ishii S., Takahashi M., Miyakawa T.
- Organizer
  Society for Neuroscience 43rd Annual Meeting
- Place of Presentation
  米国 San Diego
- Data Source
  KAKENHI-PROJECT-25430077
[Presentation] Dysregulation of BDNF-MAPK signaling pathway in the hippocampus of mice with “immature dentate gyrus.
- Author(s)
  Hisatsugu Koshimizu, Koji Ohira, Hideo Hagihara, Keizo Takao, Tsuyoshi Takagi, Masakazu Kataoka, Shunsuke Ishii, Masami Takahashi, Tsuyoshi Miyakawa
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego , USA
- Year and Date
  2013-11-09 – 2013-11-13
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] “Immature dentate gyrus”, a candidate endophenotype for psychotic disorders, emerges after adolescence in Schnurri-2 KO mice.
- Author(s)
  Keizo Takao, Hideo Hagihara, Koji Ohira, Hirotaka Shoji, Satoko Hattori, Hisatsugu Koshimizu, Juzoh Umemori, Tsuyoshi Takagi, Shunsuke Ishii, Tsuyoshi Miyakawa
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego , USA
- Year and Date
  2013-11-09 – 2013-11-13
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] Dysregulation of BDNF-MAPK signaling pathway in the hippocampus of mice with “immature dentate gyrus”
- Author(s)
  Hisatsugu Koshimizu, Koji Ohira, Hideo Hagihara, Keizo Takao, Tsuyoshi Takagi, Masakazu Kataoka, Shunsuke Ishii, Masami Takahashi, Tsuyoshi Miyakawa
- Organizer
  12th Annual Molecular and Cellular Congnition Society Meeting
- Place of Presentation
  San Diego , USA
- Year and Date
  2013-11-07 – 2013-11-08
- Data Source
  KAKENHI-PROJECT-25242078
[Presentation] “Immature dentate gyrus”, a candidate endophenotype for psychotic disorders, emerges after adolescence in Schnurri-2 KO mice.
- Author(s)
  Keizo Takao, Hideo Hagihara, Koji Ohira, Hirotaka Shoji, Satoko Hattori, Hisatsugu Koshimizu, Juzoh Umemori, Tsuyoshi Takagi, Shunsuke Ishii, Tsuyoshi Miyakawa
- Organizer
  12th Annual Molecular and Cellular Congnition Society Meeting
- Place of Presentation
  San Diego , USA
- Year and Date
  2013-11-07 – 2013-11-08
- Data Source
  KAKENHI-PROJECT-25242078

1. MIYAKAWA Tsuyoshi (10301780)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
2. TAKAO Keizo (80420397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. Ohira Koji (80402832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. Hagihara Hideo (80514504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. UMEMORI Juzoh (20462913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 安達直樹 (00450601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 鈴木辰吾 (50451430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松岡秀忠 (90374991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大西浩史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 的崎尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koshimizu Hisatsugu 小清水 久嗣

小清水 久嗣 コシミズ ヒサツグ

KOSHIMIZU Hisatsugu 小清水 久嗣

Research Projects

Research Products

Co-Researchers

中脳黒質におけるCRH結合蛋白質の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis and regulation of bi-directional changes in maturation status of brain cells utilising in vitro hightrokghput assay systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation and regulation of bi-directional changes in neuronal maturation status

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 脳科学辞典「行動テストバッテリー」2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] A genome-wide association study identifies a novel locus associated with depressive state in the Japanese population2017

Author(s)

Organizer

Data Source

[Presentation] A genome-wide association study identifies a novel locus associated with depressive state in the Japanese population2017

Author(s)

Organizer

Data Source

[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Contrasting expression patterns of inflammation-related genes in mouse models of depression and psychosis.2016

Author(s)

Organizer

Place of Presentation

Koshimizu Hisatsugu 小清水久嗣

小清水久嗣コシミズヒサツグ

KOSHIMIZU Hisatsugu 小清水久嗣