Ishikawa Mitsuru 石川充

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ISHIKAWA Mitsuru 石川充

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Researcher Number	10613995
Other IDs
Affiliation (Current)	2023: 慶應義塾大学, 医学部(信濃町), 訪問講師
Affiliation (based on the past Project Information) *help	2023: 慶應義塾大学, 医学部, 講師 2022: 慶應義塾大学, 医学部(信濃町), 特任講師 2019 – 2021: 慶應義塾大学, 医学部(信濃町), 特任助教 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 特任助教 2014 – 2015: 慶應義塾大学, 医学部, 特任助教 2011: 富山大学, 大学院・医学薬学研究部(薬学), 助教
Review Section/Research Field	Principal Investigator Biological pharmacy / Neurophysiology / General neuroscience / Pediatrics / Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 52:General internal medicine and related fields / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Biological Sciences
Keywords	Principal Investigator iPS細胞 / 精神疾患 / 抑制性神経細胞 / スクリーニング / アクチン / SRF / 転写因子 / 樹状突起 / Rho / iPS 細胞 … More / ゲノム編集 / 大脳皮質 / オルガノイド / 神経発達 / 進化 / 霊長類 / 分節重複 / 重複遺伝子 / 興奮性神経細胞 / 進化生物学 / SRGAP2 / 細胞移動 / Neurogenin2 / 不死化リンパ芽球 / ダイレクトリプログラミング / iN / エピゲノム / 神経疾患 / 末梢血細胞 / 直接誘導 / 神経科学 / 脳神経疾患 / 発生・分化 / 脳・神経 / 神経分化 … More Except Principal Investigator 統合失調症 / 双極性障害 / iPS細胞 / 視床室傍核 / ミトコンドリアDNA / カルシウム / トランスクリプトーム解析 Less

発達性てんかん性脳症の個別化医療を促進させる細胞種特異的iPS神経系培養基盤の導出Principal Investigator
- Principal Investigator
  
  石川充
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Keio University
Custom generation of human brain cells: establishment of in vitro differentiation system for whole cell typesPrincipal Investigator
- Principal Investigator
  
  石川充
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Keio University
サブタイプ特異的な抑制性神経の選択作出が可能にする精神疾患神経活動スクリーニングPrincipal Investigator
- Principal Investigator
  
  石川充
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Keio University
Constructive understanding of bipolar disorder and schizophrenia by transomics and modeling
- Principal Investigator
  
  加藤忠史
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
  Institute of Physical and Chemical Research
Direct differentiation of peripheral blood cells into neurons for the analysis of epigenetic-related diseasesPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Mitsuru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Keio University
In vitro brain development analysis using iPS cells and genome editing technologiesPrincipal Investigator
- Principal Investigator
  
  Ishikawa Mitsuru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Keio University
Functional analysis of synapse morphology regulated by MKL, an actin-binding coactivatorPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Mitsuru
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Toyama

All 2021 2016 2015 2014 2011

All Journal Article Presentation

[Journal Article] Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region2021
- Author(s)
  1.Ikegame T, Hidaka Y, Nakachi Y, Murata Y, Watanabe R, Sugawara H, Asai T, Kiyota E, Saito T, Ikeda M, Sasaki T, Hashimoto M, Ishikawa T, Takebayashi M, Iwata N, Kakiuchi C, Kato T, Kasai K, Bundo M, Iwamoto K
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11;11(1) Pages: 119-119
- DOI
  10.1038/s41398-021-01242-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15486, KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-18H05435, KAKENHI-PROJECT-19K17056, KAKENHI-PLANNED-16H06399, KAKENHI-PLANNED-18H05430, KAKENHI-PROJECT-18H02753, KAKENHI-PROJECT-18H02756
[Journal Article] Functional neurons generated from T cell-derived iPSCs for neurological disease modeling2016
- Author(s)
  Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, Nishimura K, Kurosawa H, Yoshikawa T, Takahashi T, Nakanishi M, Ohyama M, Hattori N, Akamatsu W, Okano H.
- Journal Title
  
  STEM CELL REPORTS
  
  Volume: 6 Pages: 422-35
- DOI
  10.1016/j.stemcr.2016.01.010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06780, KAKENHI-PROJECT-15K09849, KAKENHI-PROJECT-15K15041, KAKENHI-PROJECT-26830018, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-26870074, KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-16K08280
[Journal Article] Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.2016
- Author(s)
  Naoki Ichiyanagi, Koki Fujimori, Masato Yano, Chikako Ishihara-Fujisaki, Takefumi Sone, Tetsuya Akiyama, Yohei Okada, Wado Akamatsu, Takuya Matsumoto, Mitsuru Ishikawa, Yoshinori Nishimoto, Yasuharu Ishihara, Tetsushi Sakuma, Takashi Yamamoto, Hitomi Tsuiji, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 6 Pages: 496-510
- DOI
  10.1016/j.stemcr.2016.02.011
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-25430055, KAKENHI-PROJECT-26830018, KAKENHI-PROJECT-15H04278, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-25293199, KAKENHI-PLANNED-26117007, KAKENHI-PUBLICLY-15H01568, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K07247
[Journal Article] Cellular localization and dendritic function of rat isoforms of the SRF coactivator MKL1 in cortical neurons2014
- Author(s)
  Ishikawa M, Shiota J, Ishibashi Y, Hakamata T, Shoji S, Fukuchi M, Tsuda M, Shirao T, Sekino Y, Baraban JM, Tabuchi A.
- Journal Title
  
  Neuroreport
  
  Volume: 25 Pages: 585-592
- DOI
  10.1097/wnr.0000000000000141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460064, KAKENHI-PROJECT-26830018
[Presentation] Widespread analysis of TSSs in human iPSC-derived neurons using CAGE-SEQ2016
- Author(s)
  石川充
- Organizer
  日本神経科学大会
- Place of Presentation
  パシフィコ横浜、神奈川
- Data Source
  KAKENHI-PROJECT-26830018
[Presentation] 神経フェリチン症（Neuroferritinopathy）患者由来iPS細胞の樹立と病態モデルの検討2015
- Author(s)
  森本悟、石川充、西田勝也、岡本理志、駒野肇、赤松和土、Holly J Garringer、Vidal Ruben、白石泰三、高尾昌樹、岡野栄之
- Organizer
  第１４回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26830018
[Presentation] Expression analysis of imprinted genes in Angelman syndrome patient derived-iPSCs and iPSCs-derived neurons2015
- Author(s)
  Mitsuru Ishikawa, Hironobu Okuno, Shoma Tanaka, Wado Akamatsu, Shinji Saitoh, Kenjiro Kosaki, Hideyuki Okano
- Organizer
  The 11th International Workshop on Advanced Genomics
- Place of Presentation
  一ツ橋ホール（東京都千代田区）
- Year and Date
  2015-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830018
[Presentation] ヒトiPS細胞由来神経細胞における活動依存的遺伝子発現機構の解析2015
- Author(s)
  石川充、赤松和土、駒野肇、岡野栄之
- Organizer
  第１４回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26830018
[Presentation] Molecular and functional characterization of Angelman syndrome patient-derived iPSCs and neurons2015
- Author(s)
  Mitsuru Ishikawa, Hironobu Okuno, Shoma Tanaka, Yuki Nakatake, Wado Akamatsu, Shinji Saitoh, Kenjiro Kosaki, Minoru Ko, Hideyuki Okano
- Organizer
  29th International Mammalian Genome Conference
- Place of Presentation
  横浜開港記念館（神奈川県横浜市）
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830018
[Presentation] ヒトiPS細胞由来興奮性ニューロン分化誘導技術を用いた神経発達障害における遺伝子発現と細胞形態解析2015
- Author(s)
  石川充、奥野博庸、田中翔真、中武悠樹、赤松和土、小崎健次郎、齋藤伸治、洪実、岡野栄之
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26830018
[Presentation] an actin-binding coactivator for SRF, is involved in a novel signaling pathway for activin-regulated dendritic morphology in rat cortical neurons2011
- Author(s)
  石川充
- Organizer
  The 6th International Conference of Neurons and Brain Disease
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23890065
[Presentation] MKL, an actin-binding coactivator for SRF, is involved in a novel signa-ling pathway for activin-regulated dendritic morphology in rat cortical neurons2011
- Author(s)
  石川充
- Organizer
  The 6^<th> International Conference of Neurons and Brain Diseases
- Place of Presentation
  ANAクラウンプラザホテル(富山)
- Data Source
  KAKENHI-PROJECT-23890065
[Presentation] Identification and characterization of a novel transcript of rat MKL1, the actin-binding coactivator for SRF : the effect on transcriptional activation and neuronal morphology in rat cortical neurons2011
- Author(s)
  石川充
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-23890065
[Presentation] アクチン結合性転写活性化因子MKLが関与するアクチビン誘導性のラット大脳皮質ニューロン樹状突起形態制御における新規シグナル伝達経路の解析2011
- Author(s)
  石川充
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23890065
[Presentation] Identification and characterization of a novel transcript of rat MKL1, the actin-binding coactivator for SRF : the effect on transcriptional activity and neuronal morphology in rat cortical neurons2011
- Author(s)
  石川充
- Organizer
  第34回日本分子神経生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-23890065
[Presentation] アクチン結合性転写活性化因子MKLが関与するアクチビン誘導性のラット大脳皮質ニューロン樹状突起形態制御における新規シグナル伝達経路の解析2011
- Author(s)
  石川充
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23890065

1. 加藤忠史 (30214381)

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# of Collaborated Products: 1 results
2. 吉川武男 (30249958)

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3. TANAKA Shoma

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# of Collaborated Products: 3 results
4. TOYOSHIMA Manabu

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5. FUKUCHI Mamoru

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6. SUGAWARA Hiroko

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7. TSUIJI Hitomi

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8. SUZUKI Naoki

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9. 佐藤栄人

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10. 多田敬典

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11. 服部信孝

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12. 小林俊秀

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13. 今居譲

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14. 西村健

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15. 葛巻直子

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16. 田渕明子

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17. 笠井清登

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18. 池亀天平

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19. 文東美紀

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20. 岩本和也

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21. 竹林実

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22. 曽根岳史

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23. 岡田洋平

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24. 岡野栄之

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25. 青木正志

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26. 割田仁

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27. 矢野真人

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Ishikawa Mitsuru 石川 充

ISHIKAWA Mitsuru 石川 充

Research Projects

Research Products

Co-Researchers

発達性てんかん性脳症の個別化医療を促進させる細胞種特異的iPS神経系培養基盤の導出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Custom generation of human brain cells: establishment of in vitro differentiation system for whole cell typesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

サブタイプ特異的な抑制性神経の選択作出が可能にする精神疾患神経活動スクリーニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Constructive understanding of bipolar disorder and schizophrenia by transomics and modeling

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Direct differentiation of peripheral blood cells into neurons for the analysis of epigenetic-related diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vitro brain development analysis using iPS cells and genome editing technologiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of synapse morphology regulated by MKL, an actin-binding coactivatorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional neurons generated from T cell-derived iPSCs for neurological disease modeling2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular localization and dendritic function of rat isoforms of the SRF coactivator MKL1 in cortical neurons2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Widespread analysis of TSSs in human iPSC-derived neurons using CAGE-SEQ2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 神経フェリチン症（Neuroferritinopathy）患者由来iPS細胞の樹立と病態モデルの検討2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Expression analysis of imprinted genes in Angelman syndrome patient derived-iPSCs and iPSCs-derived neurons2015

Author(s)

Ishikawa Mitsuru 石川充

ISHIKAWA Mitsuru 石川充