SEKI Yuta 関優太

Researcher Number	10615636
Affiliation *help	2015 – 2018 : 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 2012 : 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 2011 : 財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員
Review Section/Research Field	Principal Investigator Laboratory animal science / Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator モデルマウス / 遺伝学 / ミオシンVI / ミオシン6 / 遺伝子 / ゲノム / 不動毛 / Myosin VI / 難聴モデルマウス / 進行性難聴 … More

内耳高発現ミオシン6アイソフォームの機能解析を起点した不動毛形成機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  関優太
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
マウス進行性難聴発症に作用する機能ゲノム多型の同定Principal InvestigatorOngoing
- Principal Investigator
  
  関優太
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Responsible gene identification and elucidation of molecular interaction to participate in the stereocilia formation based on mouse forward geneticsPrincipal Investigator
- Principal Investigator
  
  SEKI Yuta
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Otorhinolaryngology
- Research Institution
  公益財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research

All 2016 2015 2013 2012 2011

All Journal Article Presentation

[Journal Article] Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.2016
- Author(s)
  Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami R, Yonekawa H, Kikkawa Y
- Journal Title
  
  Hum Mol Genet
  
  Volume : 印刷中 Pages : 2045-2059
- DOI
  10.1093/hmg/ddw078
- Peer Reviewed / Int'l Joint Research / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J06119, KAKENHI-PROJECT-25430097, KAKENHI-PROJECT-25293058, KAKENHI-PROJECT-15H04291, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-15K18393
[Presentation] Myosin VI変異ヘテロ接合体が発症する進行性難聴の病態.2016
- Author(s)
  関　優太, 宮坂勇輝, 鈴木沙理, 吉川欣亮.
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール（神奈川県川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K18393
[Presentation] Myosin VI変異体の感覚毛－細胞間融合プロセスと機能低下型アレルに起因した難聴発症2015
- Author(s)
  関　優太，宮坂勇輝，鈴木沙理，吉川欣亮
- Organizer
  第12回北海道実験動物研究会総会・学術集会
- Place of Presentation
  北海道大学（北海道，札幌市）
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-15K18393
[Presentation] Myosin VI新規機能低下型アレルの解析で明らかとなった感覚毛－細胞間融合プロセスとハプロ不全2015
- Author(s)
  関　優太，宮坂勇輝，鈴木沙理，吉川欣亮
- Organizer
  第29回モロシヌス研究会
- Place of Presentation
  かんぽの宿有馬（兵庫県，神戸市）
- Year and Date
  2015-07-03
- Data Source
  KAKENHI-PROJECT-15K18393
[Presentation] A new spontaneous mutation in the mouse Myosin VI gene2013
- Author(s)
  Yuta Seki, Kunie Matsuoka, Sari Suzuki, Yuki Miyasaka, Yasuhiro Oshiba, Kenta Wada, Hirohide Takebayashi, Yoshiaki Kikkawa
- Organizer
  9th Molecular Biology of Hearing & Deafness Conference
- Place of Presentation
  Stanford School of Medicine
- Data Source
  KAKENHI-PROJECT-23890253
[Presentation] 内耳有毛細胞の不動毛形成・維持に必須なMyosin VIアイソフォームの存在.2012
- Author(s)
  関　優太，鈴木沙理，和田健太，若菜茂晴，中潟直己，竹林浩秀，吉川欣亮
- Organizer
  第59回日本実験動物学会総会
- Place of Presentation
  別府国際コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23890253
[Presentation] 内耳有毛細胞の不動毛形成・維持に必須なMyosin VIアイソフォームの存在2012
- Author(s)
  関優太
- Organizer
  日本実験動物科学・技術九州2012(第59回日本実験動物学会総会、第46回日本実験動物技術者協会総会)
- Place of Presentation
  別府国際コンベンションセンター
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-23890253
[Presentation] 内耳有毛細胞のstereocilia形成・維持に異常を示す2つのMyosin VI突然変異アレルの同定2012
- Author(s)
  関優太
- Organizer
  第26回モロシヌス研究会
- Place of Presentation
  東京大学
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-23890253
[Presentation] 行動異常および難聴を示す新規マウス突然変異体の原因遺伝子の同定2011
- Author(s)
  関優太
- Organizer
  北海道実験動物研究会・日本実験動物技術者協会北海道支部合同学術集会
- Place of Presentation
  北海道大学
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-23890253
[Presentation] 行動異常および難聴を示す新規マウス突然変異体の原因遺伝子の同定2011
- Author(s)
  関優太
- Organizer
  北海道実験動物研究会・日本実験動物技術者協会北海道支部合同学術集会
- Place of Presentation
  北海道大学
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-23890253

1. YASAKA TAKU

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
2. TAKADA TOYOYUKI

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
3. 日比野浩

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
4. 設楽浩志

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
5. 吉川欣亮

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
6. 米川博通

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

SEKI Yuta 関 優太

Research Projects

Research Products

Co-Researchers

内耳高発現ミオシン6アイソフォームの機能解析を起点した不動毛形成機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マウス進行性難聴発症に作用する機能ゲノム多型の同定Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Responsible gene identification and elucidation of molecular interaction to participate in the stereocilia formation based on mouse forward geneticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Myosin VI変異ヘテロ接合体が発症する進行性難聴の病態.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Myosin VI変異体の感覚毛－細胞間融合プロセスと機能低下型アレルに起因した難聴発症2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Myosin VI新規機能低下型アレルの解析で明らかとなった感覚毛－細胞間融合プロセスとハプロ不全2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A new spontaneous mutation in the mouse Myosin VI gene2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 内耳有毛細胞の不動毛形成・維持に必須なMyosin VIアイソフォームの存在.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 内耳有毛細胞の不動毛形成・維持に必須なMyosin VIアイソフォームの存在2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 内耳有毛細胞のstereocilia形成・維持に異常を示す2つのMyosin VI突然変異アレルの同定2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 行動異常および難聴を示す新規 マウス突然変異体の原因遺伝子の同定2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 行動異常および難聴を示す新規マウス突然変異体の原因遺伝子の同定2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

SEKI Yuta 関優太

[Presentation] 行動異常および難聴を示す新規マウス突然変異体の原因遺伝子の同定2011